1PVJA

Crystal structure of the streptococcal pyrogenic exotoxin b (speb)- inhibitor complex
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
368
structure length
339
Chain Sequence
FARNEKEAKDSAITFIQKIKLDKVNLGGELSGSNMYVYNISTGGFVIVSGDKRSPEILGYSTSGSFDANGKENIASFMESYVEQIKENKKLDTTYAQPVVKSLLDSKGIHYNQGNPYNLLTPVIEKVKPGEQSFVGQHAATGCVATATAQIMKYHNYPNKGLKDYTYTLSSNNPYFNHPKNLFAAISTRQYNWNNILPTYSGRESNVQKMAISELMADVGISVDMDYGPSSGSAGSSRVQRALKENFGYNQSVHQINRGDFSKQDWEAQIDKELSQNQPVYYQGVGKVGGHAFVIDGADGRNFYHVNWGWGGVSDGFFRLDALNPGFNGYQSAVVGIKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
publication title Inhibition of autoprocessing of the streptococcal pyrogenic exotoxin B (speB). Crystal structure of the proenzyme-inhibitor complex
rcsb
molecule keywords pyrogenic exotoxin B
total genus 105
structure length 339
sequence length 368
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.10: Streptopain.
pdb deposition date 2003-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01640 Peptidase_C10 Peptidase C10 family
A PF13734 Inhibitor_I69 Spi protease inhibitor
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.910.30 Alpha Beta 2-Layer Sandwich Protein Binding, DinI Protein; Chain A Protein Binding, DinI Protein; Chain A 1pvjA02
3.90.70.50 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 1pvjA01
1DKIA 3BB7A 2JTCA 1PVJA 4D8BA 3BBAA 4RKXA 4D8EA 2UZJA 4D8IA
chains in the Genus database with same CATH superfamily
3V6CA 3NHEA 3GCBA 2R6NA 3PRMA 4WA6A 1ICFA 3PW3A 4RKXA 3F5VA 3BCNA 1PADA 1MDWA 2NQIA 1CS8A 3KWBX 1MHWA 2C0YA 1F29A 3TMPA 4OEMA 3MP2A 1QOLA 1YZBA 4D8EA 1SP4B 1U9QX 2GFOA 4I04A 3B21A 2OULA 3W30A 2VHSA 4PP1A 3V6EA 2YJ8A 3H7DA 4N8WA 3BB7A 4Q8HA 8PCHA 4FJCA 2F1GA 4BS5A 1FH0A 3E9SA 3K9MA 4MI7A 2FTDA 1AU0A 4YYWA 1BY8A 3I06A 2R9NA 4YYSA 4D8IA 3IHPA 2B1MA 3CBKA 3KX1A 1MS6A 3HWNA 4BPVA 3OVXA 1U2MA 2PNSA 2DCAA 1GHHA 1DEUA 3P5XA 1NQCA 4X6HA 3N3GA 4R3DA 1NB3A 3C0RA 1U9VA 4I07A 1DKIA 3D6SA 1U5IA 1KXRA 4P6GA 1CPJA 2FRAA 3N3KA 1BGOA 4RF0A 1KHQA 4FIPA 1AYUA 1EWOA 5J94A 4CDEB 3WXFA 2FYEA 5EZSA 3PDFA 4IP3A 2Y6EA 5JZEA 4AXLA 4PT5A 2FO5A 2DZZA 2DC8A 3LXSA 4BQVA 4FK5A 2HD5A 2CIOA 3RNVA 1HUCB 4QH6A 1PBHA 4I05A 1PXVA 4N79A 2AU1A 5CHTA 2DCBA 1YVBA 3H89A 1CV8A 1CQDA 1Y4HA 3OISA 3MHHA 3BY4A 4ZUXU 2AYOA 1CB5A 1TLOA 4CDFB 1BQIA 1POPA 4BOPA 4BOSA 1KHPA 3PHUA 2IBIA 2AS8A 4BSQA 3OF9A 2AUZA 1EWMA 4IUMA 1AU4A 1EF7A 2DC9A 5KO3A 4REZA 4K7CA 1QXPA 2ATOA 2JQFR 2Z84A 3USVA 4XR7A 1VJVA 2BDLA 4YYUA 1QMYA 2R9CA 3P5UA 3P5WA 1M6DA 1GLOA 2HH5A 1IWDA 1PCIA 4MM3B 3P5VA 4MZSA 3BC3A 3KWZA 2FT2A 5F02A 3F75A 2ARYA 3HHAA 2YJCA 3WXEA 1MEMA 4OVZA 4GUAA 3BOWA 4W4UA 1TL9A 4XZXA 4YYRA 3KFQA 1F2CA 1AU3A 4MZOA 2H7JA 2XU5A 2R9FA 3PT2A 2UZJA 4PI3A 2E00A 1XKGA 2XU1A 2R9OA 3TRKA 1SNKA 3BWKA 3S3QA 1EWPA 3N4CA 2CB5A 4ZTBA 1O0EA 2FE8A 2FRQA 3DF0A 4AXMA 1ME4A 3K24A 3IV2A 1AYVA 1K3BB 2JQGR 3IUTA 4WURA 5EF4A 5FPWA 2Y5BA 3OQCA 3CH3X 1ZIVA 3HD3A 3LFYA 1STFE 2NQAA 3MTNA 5EZQA 4YV8A 5E6JA 3QSDA 2XU3A 2AYNA 1F2BA 2DC7A 2PREA 3O0UA 1NLJA 3H8CA 1NL6A 4KLBA 1ATKA 4OELA 3BBAA 4P6EA 2P86A 2DJFB 2P7UA 2J7QC 2XU4A 2E03A 1CSBB 2PADA 2AVWA 2AIMA 4BOUA 3OF8A 4X6IA 1YK7A 5A24A 1THEA 1YT7A 3CBJA 1A6RA 3BPFA 2AUXA 1ZCMA 1AYWA 1KFUL 4YVAA 3W31A 3RVWA 4HXDB 7PCKA 2BTWB 4XUIA 4RNAA 2OP3A 4KQTA 4YYQA 2FQ9A 4P16A 1F2AA 2GHUA 2HHNA 1ITOA 1U9XA 1TU6A 4RF1A 4W5CA 1PPOA 1MIRA 3PNRA 4OW0A 2DCDA 5CVOB 4W5BA 5CVMA 3AI8A 3ZUAA 2NQDB 1U9WA 2O6XA 1YALA 1JQPA 2G7YA 2HXZA 3O65A 1PPPA 1GCBA 3ZNHA 2VHFA 2R9MA 1AECA 3OVZA 1NB5A 2JTCA 1AU2A 4EVXA 4QRXA 3IMAA 2DCCA 3U8EA 1DF0A 3KW9A 4YYVA 1PPNA 4BS6A 3QT4A 2BU3A 5K16A 4CZWA 5CVNB 1CTEA 4DMXA 3PHWA 3IEJA 3RVVA 2F7DA 3MTVA 3C9EA 1YK8A 3E1ZB 1Q6KA 3IFUA 1MEGA 4Q8GA 2E01A 3KSEA 1PIPA 4QRGA 4CDDB 5JA7A 5EGWA 2ACTA 2NQGA 4M0WA 1S4VA 2JRIA 1SG2A 1EWLA 4PADA 3K8UA 4G54A 1QDQA 2B1NA 3TNXA 3KKUA 3ERVA 2DZYA 9PAPA 1PPDA 4MSXA 1GMYA 4D8BA 1AIMA 4PP2E 2G8EA 2PBHA 4BOZA 2AGAA 5CHVA 1CVZA 2HWKA 2G8JA 4OVZB 2YJ9A 4X6JA 4RY2A 2BTWA 3CH2X 4DMYA 5JH3A 1ME3A 3B79A 2DJGB 3WXGA 5PADA 2J7QA 2YJ2A 4N4ZA 3RVXA 2FUDA 4HWYA 3BPMA 1PE6A 6PADA 1UKFA 1GECE 1PVJA 1CJLA 2IPPB 2DOSA 2BDZA 1Y08A 3MORA 2P0RA 1KFXL 3IOQA 3MJ5A 4CDCB 3I3TA 4QRVA 1BP4A 2WBFX 4A5UA 1VSNA 3S3RA 3PRPA 2E02A 3M99A 3MHSA 2G6DA 4BOQA 3H8BA 1X9YA 4QBBA 3QJ3A 3H6SA 1NPZA 3O1GA 2DC6A 2YJBA 3PSEA 3HHIA 2OZ2A 3PHXA 3PBHA
chains in the Genus database with same CATH topology
2BU3A 4WURA 3PRMA 3OQCA 3BY4A 3PHWA 3MTVA 4RKXA 3IFUA 5EZQA 5E6JA 4BOPA 4BOSA 4M0WA 3TMPA 3PHUA 2JRIA 3MP2A 1YZBA 4D8EA 4IUMA 3BBAA 3B21A 3W30A 5KO3A 4REZA 2J7QC 4D8BA 4BOZA 4BOUA 2AGAA 2HWKA 2Z84A 3BB7A 4OVZB 3E9SA 4MI7A 2BTWA 4MM3B 4D8IA 3W31A 4HXDB 2BTWB 4RNAA 2J7QA 4P16A 4OVZA 4GUAA 4R3DA 4RF1A 1UKFA 3C0RA 4XZXA 1DKIA 1PVJA 2DOSA 4RF0A 4OW0A 3MJ5A 3PT2A 2UZJA 5EZSA 3TRKA 4A5UA 4IP3A 5JZEA 3PRPA 4PT5A 3O65A 4ZTBA 3ZNHA 4BOQA 2FE8A 3RNVA 3PSEA 2JTCA 4EVXA 3PHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DKI A;  3BB7 A;  2JTC A;  1PVJ A;  4D8B A;  3BBA A;  4RKX A;  4D8E A;  2UZJ A;  4D8I A; 
#chains in the Genus database with same CATH topology
 3V6C A;  3NHE A;  3GCB A;  2R6N A;  3PRM A;  4WA6 A;  1ICF A;  3PW3 A;  4RKX A;  3F5V A;  3BCN A;  1PAD A;  1MDW A;  2NQI A;  1CS8 A;  3KWB X;  1MHW A;  2C0Y A;  1F29 A;  3TMP A;  4OEM A;  3MP2 A;  1QOL A;  1YZB A;  4D8E A;  1SP4 B;  1U9Q X;  2GFO A;  4I04 A;  3B21 A;  2OUL A;  3W30 A;  2VHS A;  4PP1 A;  3V6E A;  2YJ8 A;  3H7D A;  4N8W A;  3BB7 A;  4Q8H A;  8PCH A;  4FJC A;  2F1G A;  4BS5 A;  1FH0 A;  3E9S A;  3K9M A;  4MI7 A;  2FTD A;  1AU0 A;  4YYW A;  1BY8 A;  3I06 A;  2R9N A;  4YYS A;  4D8I A;  3IHP A;  2B1M A;  3CBK A;  3KX1 A;  1MS6 A;  3HWN A;  4BPV A;  3OVX A;  1U2M A;  2PNS A;  2DCA A;  1GHH A;  1DEU A;  3P5X A;  1NQC A;  4X6H A;  3N3G A;  4R3D A;  1NB3 A;  3C0R A;  1U9V A;  4I07 A;  1DKI A;  3D6S A;  1U5I A;  1KXR A;  4P6G A;  1CPJ A;  2FRA A;  3N3K A;  1BGO A;  4RF0 A;  1KHQ A;  4FIP A;  1AYU A;  1EWO A;  5J94 A;  4CDE B;  3WXF A;  2FYE A;  5EZS A;  3PDF A;  4IP3 A;  2Y6E A;  5JZE A;  4AXL A;  4PT5 A;  2FO5 A;  2DZZ A;  2DC8 A;  3LXS A;  4BQV A;  4FK5 A;  2HD5 A;  2CIO A;  3RNV A;  1HUC B;  4QH6 A;  1PBH A;  4I05 A;  1PXV A;  4N79 A;  2AU1 A;  5CHT A;  2DCB A;  1YVB A;  3H89 A;  1CV8 A;  1CQD A;  1Y4H A;  3OIS A;  3MHH A;  3BY4 A;  4ZUX U;  2AYO A;  1CB5 A;  1TLO A;  4CDF B;  1BQI A;  1POP A;  4BOP A;  4BOS A;  1KHP A;  3PHU A;  2IBI A;  2AS8 A;  4BSQ A;  3OF9 A;  2AUZ A;  1EWM A;  4IUM A;  1AU4 A;  1EF7 A;  2DC9 A;  5KO3 A;  4REZ A;  4K7C A;  1QXP A;  2ATO A;  2JQF R;  2Z84 A;  3USV A;  4XR7 A;  1VJV A;  2BDL A;  4YYU A;  1QMY A;  2R9C A;  3P5U A;  3P5W A;  1M6D A;  1GLO A;  2HH5 A;  1IWD A;  1PCI A;  4MM3 B;  3P5V A;  4MZS A;  3BC3 A;  3KWZ A;  2FT2 A;  5F02 A;  3F75 A;  2ARY A;  3HHA A;  2YJC A;  3WXE A;  1MEM A;  4OVZ A;  4GUA A;  3BOW A;  4W4U A;  1TL9 A;  4XZX A;  4YYR A;  3KFQ A;  1F2C A;  1AU3 A;  4MZO A;  2H7J A;  2XU5 A;  2R9F A;  3PT2 A;  2UZJ A;  4PI3 A;  2E00 A;  1XKG A;  2XU1 A;  2R9O A;  3TRK A;  1SNK A;  3BWK A;  3S3Q A;  1EWP A;  3N4C A;  2CB5 A;  4ZTB A;  1O0E A;  2FE8 A;  2FRQ A;  3DF0 A;  4AXM A;  1ME4 A;  3K24 A;  3IV2 A;  1AYV A;  1K3B B;  2JQG R;  3IUT A;  4WUR A;  5EF4 A;  5FPW A;  2Y5B A;  3OQC A;  3CH3 X;  1ZIV A;  3HD3 A;  3LFY A;  1STF E;  2NQA A;  3MTN A;  5EZQ A;  4YV8 A;  5E6J A;  3QSD A;  2XU3 A;  2AYN A;  1F2B A;  2DC7 A;  2PRE A;  3O0U A;  1NLJ A;  3H8C A;  1NL6 A;  4KLB A;  1ATK A;  4OEL A;  3BBA A;  4P6E A;  2P86 A;  2DJF B;  2P7U A;  2J7Q C;  2XU4 A;  2E03 A;  1CSB B;  2PAD A;  2AVW A;  2AIM A;  4BOU A;  3OF8 A;  4X6I A;  1YK7 A;  5A24 A;  1THE A;  1YT7 A;  3CBJ A;  1A6R A;  3BPF A;  2AUX A;  1ZCM A;  1AYW A;  1KFU L;  4YVA A;  3W31 A;  3RVW A;  4HXD B;  7PCK A;  2BTW B;  4XUI A;  4RNA A;  2OP3 A;  4KQT A;  4YYQ A;  2FQ9 A;  4P16 A;  1F2A A;  2GHU A;  2HHN A;  1ITO A;  1U9X A;  1TU6 A;  4RF1 A;  4W5C A;  1PPO A;  1MIR A;  3PNR A;  4OW0 A;  2DCD A;  5CVO B;  4W5B A;  5CVM A;  3AI8 A;  3ZUA A;  2NQD B;  1U9W A;  2O6X A;  1YAL A;  1JQP A;  2G7Y A;  2HXZ A;  3O65 A;  1PPP A;  1GCB A;  3ZNH A;  2VHF A;  2R9M A;  1AEC A;  3OVZ A;  1NB5 A;  2JTC A;  1AU2 A;  4EVX A;  4QRX A;  3IMA A;  2DCC A;  3U8E A;  1DF0 A;  3KW9 A;  4YYV A;  1PPN A;  4BS6 A;  3QT4 A;  2BU3 A;  5K16 A;  4CZW A;  5CVN B;  1CTE A;  4DMX A;  3PHW A;  3IEJ A;  3RVV A;  2F7D A;  3MTV A;  3C9E A;  1YK8 A;  3E1Z B;  1Q6K A;  3IFU A;  1MEG A;  4Q8G A;  2E01 A;  3KSE A;  1PIP A;  4QRG A;  4CDD B;  5JA7 A;  5EGW A;  2ACT A;  2NQG A;  4M0W A;  1S4V A;  2JRI A;  1SG2 A;  1EWL A;  4PAD A;  3K8U A;  4G54 A;  1QDQ A;  2B1N A;  3TNX A;  3KKU A;  3ERV A;  2DZY A;  9PAP A;  1PPD A;  4MSX A;  1GMY A;  4D8B A;  1AIM A;  4PP2 E;  2G8E A;  2PBH A;  4BOZ A;  2AGA A;  5CHV A;  1CVZ A;  2HWK A;  2G8J A;  4OVZ B;  2YJ9 A;  4X6J A;  4RY2 A;  2BTW A;  3CH2 X;  4DMY A;  5JH3 A;  1ME3 A;  3B79 A;  2DJG B;  3WXG A;  5PAD A;  2J7Q A;  2YJ2 A;  4N4Z A;  3RVX A;  2FUD A;  4HWY A;  3BPM A;  1PE6 A;  6PAD A;  1UKF A;  1GEC E;  1PVJ A;  1CJL A;  2IPP B;  2DOS A;  2BDZ A;  1Y08 A;  3MOR A;  2P0R A;  1KFX L;  3IOQ A;  3MJ5 A;  4CDC B;  3I3T A;  4QRV A;  1BP4 A;  2WBF X;  4A5U A;  1VSN A;  3S3R A;  3PRP A;  2E02 A;  3M99 A;  3MHS A;  2G6D A;  4BOQ A;  3H8B A;  1X9Y A;  4QBB A;  3QJ3 A;  3H6S A;  1NPZ A;  3O1G A;  2DC6 A;  2YJB A;  3PSE A;  3HHI A;  2OZ2 A;  3PHX A;  3PBH A; 
#chains in the Genus database with same CATH homology
 2BU3 A;  4WUR A;  3PRM A;  3OQC A;  3BY4 A;  3PHW A;  3MTV A;  4RKX A;  3IFU A;  5EZQ A;  5E6J A;  4BOP A;  4BOS A;  4M0W A;  3TMP A;  3PHU A;  2JRI A;  3MP2 A;  1YZB A;  4D8E A;  4IUM A;  3BBA A;  3B21 A;  3W30 A;  5KO3 A;  4REZ A;  2J7Q C;  4D8B A;  4BOZ A;  4BOU A;  2AGA A;  2HWK A;  2Z84 A;  3BB7 A;  4OVZ B;  3E9S A;  4MI7 A;  2BTW A;  4MM3 B;  4D8I A;  3W31 A;  4HXD B;  2BTW B;  4RNA A;  2J7Q A;  4P16 A;  4OVZ A;  4GUA A;  4R3D A;  4RF1 A;  1UKF A;  3C0R A;  4XZX A;  1DKI A;  1PVJ A;  2DOS A;  4RF0 A;  4OW0 A;  3MJ5 A;  3PT2 A;  2UZJ A;  5EZS A;  3TRK A;  4A5U A;  4IP3 A;  5JZE A;  3PRP A;  4PT5 A;  3O65 A;  4ZTB A;  3ZNH A;  4BOQ A;  2FE8 A;  3RNV A;  3PSE A;  2JTC A;  4EVX A;  3PHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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