3BB7A

Structure of prevotella intermedia prointerpain a fragment 39-359 (mutant c154a)
Total Genus 89
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
321
structure length
314
Chain Sequence
ANQLRELKQTHTYTVFGYTDGGFAVISADDLAPELLGVSESNFVETDNPSFKWWLKAIDEVITNAVKSNKPLNVIKPDPSKYAAEVSTLLTTTWGQQMPYNKLLPKTKKGRLITGAVATATAQVLNYFKYPVRGIGSHTVHYPANDPSGVAISADFGNTTYDWANMKDNYSGNYTEAEANAVATLMLHCGVASEMQYGGPNEGSGAYMTDCAAGLRTYFGFTDAEYITRANYTDEQWMDIVFSELTKGHPLIYGGVDAGHAFVIDGYNKAGLVSVNWGWNGDVDGYYKIDLLNPGNMYSFTAEQDMVRGVYGKP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A
pubmed doi rcsb
molecule tags Hydrolase
source organism Prevotella intermedia
molecule keywords interpain A
total genus 89
structure length 314
sequence length 321
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01640 Peptidase_C10 Peptidase C10 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.910.30 Alpha Beta 2-Layer Sandwich Protein Binding, DinI Protein; Chain A Protein Binding, DinI Protein; Chain A 3bb7A02
3.90.70.50 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3bb7A01
1DKIA 3BB7A 3BBAA 4RKXA 2JTCA 2UZJA 4D8EA 4D8IA 1PVJA 4D8BA
chains in the Genus database with same CATH superfamily
2GFOA 3WXFA 4W4UA 1ZIVA 3ZUAA 2FRAA 3N3KA 3TMPA 2YJ8A 2JRIA 3WXEA 1BQIA 3P5WA 4YYRA 3BB7A 3PT2A 3QSDA 4A5UA 3GCBA 3C9EA 4D8BA 1THEA 3WXGA 1YK8A 3HHAA 3OVZA 2FE8A 1YT7A 3O65A 1ME4A 1KHQA 5CHVA 1UKFA 3H7DA 1MDWA 1CS8A 5J94A 5EF4A 3TNXA 1BY8A 2DC8A 1EWLA 2JQFR 4W5BA 3I06A 1IWDA 1NB3A 1ICFA 2AYOA 4XR7A 3MJ5A 2AUXA 3W30A 3ZNHA 1U9QX 4RKXA 2DJGB 4CDDB 2E02A 4FIPA 2G8JA 1AU0A 4P16A 1U5IA 3PW3A 2DC7A 1BP4A 4RNAA 1TLOA 4I04A 3MHHA 2DOSA 4Q8HA 1VSNA 1Y08A 3N3GA 1F2CA 2G8EA 4RY2A 4FJCA 2HD5A 2F7DA 2DC6A 4BS5A 4RF0A 3K24A 5CVMA 2NQAA 2XU3A 8PCHA 1GHHA 1F2BA 2JTCA 4OVZA 2FQ9A 2WBFX 4D8EA 2E00A 3BOWA 1U9XA 3E9SA 3MORA 4PT5A 1VJVA 2AS8A 2P0RA 3AI8A 3LXSA 1EF7A 2FYEA 1STFE 2VHFA 4MM3B 9PAPA 2PNSA 3IHPA 3HD3A 4K7CA 3BCNA 2YJ9A 4MZOA 4X6HA 5E6JA 4PADA 1CB5A 3B79A 4R3DA 4EVXA 2YJCA 2XU4A 2E01A 3N4CA 4WA6A 1KFUL 2IBIA 2HH5A 2Y5BA 3M99A 3MTNA 2BDZA 1ATKA 4N79A 3IMAA 2DCAA 3V6EA 2FTDA 1NL6A 1PADA 3USVA 3H6SA 1CJLA 1AU4A 4MSXA 1Q6KA 4MI7A 1MEGA 4X6JA 3KX1A 1GECE 1EWMA 1YALA 4YYVA 3IV2A 3BY4A 2AIMA 3OQCA 2B1MA 2YJ2A 1JQPA 1ZCMA 3MTVA 2O6XA 3PHWA 1TL9A 2XU5A 6PADA 1X9YA 2H7JA 2VHSA 5JZEA 1U9WA 3KWBX 2P86A 3BPFA 2ARYA 3F5VA 4RF1A 4BS6A 4I07A 3PDFA 3H8BA 3QJ3A 3NHEA 1YK7A 1F2AA 2IPPB 5EGWA 4G54A 4AXLA 3I3TA 1ITOA 3QT4A 1F29A 3CH2X 1EWPA 3TRKA 1EWOA 1S4VA 1YZBA 1POPA 2OULA 4YYQA 1PXVA 1QDQA 2P7UA 3RVVA 4CDEB 1U9VA 3E1ZB 4QRGA 2CB5A 4PI3A 2BU3A 4YYUA 1AECA 1AIMA 2HHNA 5KO3A 4D8IA 1CPJA 3P5XA 5CVNB 1AYUA 2CIOA 3H89A 4CDCB 2JQGR 2YJBA 4IUMA 2G7YA 3PRMA 1XKGA 1AU2A 3HWNA 1QMYA 4BSQA 3PHXA 3OVXA 7PCKA 2GHUA 1FH0A 1GCBA 3OF9A 2DCCA 1PE6A 4PP1A 2FT2A 1AYVA 2NQDB 5PADA 2DZZA 4CZWA 3BBAA 3KFQA 2C0YA 3O1GA 1CTEA 1DKIA 2R9OA 1SG2A 2DCDA 2R6NA 4HXDB 4OW0A 4BPVA 2NQIA 1MHWA 4M0WA 1CV8A 3KW9A 3RVWA 1CQDA 3W31A 2Y6EA 4QRVA 1KXRA 2PREA 3S3RA 2AYNA 3CBJA 2AGAA 3MP2A 2DC9A 3RVXA 1O0EA 4PP2E 1KHPA 1Y4HA 1HUCB 4I05A 4CDFB 3BWKA 1NB5A 4W5CA 2HWKA 4DMYA 3KSEA 5JH3A 3P5UA 1ME3A 5F02A 3IFUA 2J7QC 2B1NA 1AYWA 3IUTA 5JA7A 1DF0A 1GMYA 4HWYA 1AU3A 3V6CA 2PADA 3HHIA 1PPDA 3PRPA 2R9FA 5A24A 4MZSA 4REZA 5EZSA 2OP3A 1PIPA 3F75A 4BOSA 1CVZA 4XUIA 4WURA 5CVOB 3PSEA 2BTWB 2AUZA 3PNRA 4N4ZA 2G6DA 2FUDA 4OELA 4BOQA 1QXPA 1MIRA 1YVBA 4BOZA 2R9MA 4ZTBA 2Z84A 2E03A 1CSBB 2NQGA 4P6GA 1A6RA 2AVWA 4YV8A 5FPWA 2AU1A 1BGOA 3ERVA 1NQCA 3PHUA 1PPPA 3S3QA 2FO5A 2DCBA 1PCIA 4BQVA 4X6IA 1NPZA 1MS6A 3DF0A 1SP4B 3IOQA 5CHTA 2ACTA 3H8CA 3OISA 1KFXL 3KKUA 4Q8GA 1PPOA 3KWZA 3C0RA 4KQTA 2J7QA 2PBHA 2FRQA 3LFYA 4BOUA 3K9MA 1GLOA 2F1GA 4QBBA 1DEUA 2HXZA 3PBHA 3O0UA 1TU6A 3BPMA 3OF8A 2DZYA 4DMXA 4YYSA 3IEJA 2BDLA 2XU1A 3D6SA 3P5VA 5K16A 4QH6A 1PBHA 1SNKA 2OZ2A 2R9CA 5EZQA 3RNVA 3BC3A 2BTWA 3U8EA 4OVZB 4ZUXU 2UZJA 1U2MA 2DJFB 1M6DA 3CBKA 2R9NA 1QOLA 4BOPA 4YYWA 1MEMA 4YVAA 4KLBA 4FK5A 3K8UA 4GUAA 4P6EA 1K3BB 2ATOA 4AXMA 3MHSA 4XZXA 4QRXA 1PVJA 1PPNA 3B21A 1NLJA 4IP3A 4N8WA 3CH3X 4OEMA
chains in the Genus database with same CATH topology
4BOZA 3PHXA 3TMPA 4ZTBA 2Z84A 2JRIA 3BB7A 3PT2A 4A5UA 4D8BA 3BBAA 4MI7A 2FE8A 3PHUA 3O65A 1DKIA 3BY4A 3OQCA 1UKFA 4HXDB 4OW0A 3MTVA 3PHWA 3MJ5A 4M0WA 3W30A 3ZNHA 5JZEA 4RKXA 3W31A 3C0RA 4P16A 4RF1A 4RNAA 2AGAA 3MP2A 2J7QA 2DOSA 4BOUA 2HWKA 3TRKA 3IFUA 4RF0A 2J7QC 1YZBA 2JTCA 4OVZA 3PRPA 4D8EA 3E9SA 4REZA 5EZQA 3RNVA 5EZSA 2BTWA 4PT5A 4OVZB 4BOSA 2UZJA 4WURA 2BU3A 4MM3B 4BOPA 3PSEA 5KO3A 2BTWB 4GUAA 4D8IA 5E6JA 4R3DA 4XZXA 4BOQA 4EVXA 1PVJA 3B21A 4IP3A 4IUMA 3PRMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DKI A;  3BB7 A;  3BBA A;  4RKX A;  2JTC A;  2UZJ A;  4D8E A;  4D8I A;  1PVJ A;  4D8B A; 
#chains in the Genus database with same CATH topology
 2GFO A;  3WXF A;  4W4U A;  1ZIV A;  3ZUA A;  2FRA A;  3N3K A;  3TMP A;  2YJ8 A;  2JRI A;  3WXE A;  1BQI A;  3P5W A;  4YYR A;  3BB7 A;  3PT2 A;  3QSD A;  4A5U A;  3GCB A;  3C9E A;  4D8B A;  1THE A;  3WXG A;  1YK8 A;  3HHA A;  3OVZ A;  2FE8 A;  1YT7 A;  3O65 A;  1ME4 A;  1KHQ A;  5CHV A;  1UKF A;  3H7D A;  1MDW A;  1CS8 A;  5J94 A;  5EF4 A;  3TNX A;  1BY8 A;  2DC8 A;  1EWL A;  2JQF R;  4W5B A;  3I06 A;  1IWD A;  1NB3 A;  1ICF A;  2AYO A;  4XR7 A;  3MJ5 A;  2AUX A;  3W30 A;  3ZNH A;  1U9Q X;  4RKX A;  2DJG B;  4CDD B;  2E02 A;  4FIP A;  2G8J A;  1AU0 A;  4P16 A;  1U5I A;  3PW3 A;  2DC7 A;  1BP4 A;  4RNA A;  1TLO A;  4I04 A;  3MHH A;  2DOS A;  4Q8H A;  1VSN A;  1Y08 A;  3N3G A;  1F2C A;  2G8E A;  4RY2 A;  4FJC A;  2HD5 A;  2F7D A;  2DC6 A;  4BS5 A;  4RF0 A;  3K24 A;  5CVM A;  2NQA A;  2XU3 A;  8PCH A;  1GHH A;  1F2B A;  2JTC A;  4OVZ A;  2FQ9 A;  2WBF X;  4D8E A;  2E00 A;  3BOW A;  1U9X A;  3E9S A;  3MOR A;  4PT5 A;  1VJV A;  2AS8 A;  2P0R A;  3AI8 A;  3LXS A;  1EF7 A;  2FYE A;  1STF E;  2VHF A;  4MM3 B;  9PAP A;  2PNS A;  3IHP A;  3HD3 A;  4K7C A;  3BCN A;  2YJ9 A;  4MZO A;  4X6H A;  5E6J A;  4PAD A;  1CB5 A;  3B79 A;  4R3D A;  4EVX A;  2YJC A;  2XU4 A;  2E01 A;  3N4C A;  4WA6 A;  1KFU L;  2IBI A;  2HH5 A;  2Y5B A;  3M99 A;  3MTN A;  2BDZ A;  1ATK A;  4N79 A;  3IMA A;  2DCA A;  3V6E A;  2FTD A;  1NL6 A;  1PAD A;  3USV A;  3H6S A;  1CJL A;  1AU4 A;  4MSX A;  1Q6K A;  4MI7 A;  1MEG A;  4X6J A;  3KX1 A;  1GEC E;  1EWM A;  1YAL A;  4YYV A;  3IV2 A;  3BY4 A;  2AIM A;  3OQC A;  2B1M A;  2YJ2 A;  1JQP A;  1ZCM A;  3MTV A;  2O6X A;  3PHW A;  1TL9 A;  2XU5 A;  6PAD A;  1X9Y A;  2H7J A;  2VHS A;  5JZE A;  1U9W A;  3KWB X;  2P86 A;  3BPF A;  2ARY A;  3F5V A;  4RF1 A;  4BS6 A;  4I07 A;  3PDF A;  3H8B A;  3QJ3 A;  3NHE A;  1YK7 A;  1F2A A;  2IPP B;  5EGW A;  4G54 A;  4AXL A;  3I3T A;  1ITO A;  3QT4 A;  1F29 A;  3CH2 X;  1EWP A;  3TRK A;  1EWO A;  1S4V A;  1YZB A;  1POP A;  2OUL A;  4YYQ A;  1PXV A;  1QDQ A;  2P7U A;  3RVV A;  4CDE B;  1U9V A;  3E1Z B;  4QRG A;  2CB5 A;  4PI3 A;  2BU3 A;  4YYU A;  1AEC A;  1AIM A;  2HHN A;  5KO3 A;  4D8I A;  1CPJ A;  3P5X A;  5CVN B;  1AYU A;  2CIO A;  3H89 A;  4CDC B;  2JQG R;  2YJB A;  4IUM A;  2G7Y A;  3PRM A;  1XKG A;  1AU2 A;  3HWN A;  1QMY A;  4BSQ A;  3PHX A;  3OVX A;  7PCK A;  2GHU A;  1FH0 A;  1GCB A;  3OF9 A;  2DCC A;  1PE6 A;  4PP1 A;  2FT2 A;  1AYV A;  2NQD B;  5PAD A;  2DZZ A;  4CZW A;  3BBA A;  3KFQ A;  2C0Y A;  3O1G A;  1CTE A;  1DKI A;  2R9O A;  1SG2 A;  2DCD A;  2R6N A;  4HXD B;  4OW0 A;  4BPV A;  2NQI A;  1MHW A;  4M0W A;  1CV8 A;  3KW9 A;  3RVW A;  1CQD A;  3W31 A;  2Y6E A;  4QRV A;  1KXR A;  2PRE A;  3S3R A;  2AYN A;  3CBJ A;  2AGA A;  3MP2 A;  2DC9 A;  3RVX A;  1O0E A;  4PP2 E;  1KHP A;  1Y4H A;  1HUC B;  4I05 A;  4CDF B;  3BWK A;  1NB5 A;  4W5C A;  2HWK A;  4DMY A;  3KSE A;  5JH3 A;  3P5U A;  1ME3 A;  5F02 A;  3IFU A;  2J7Q C;  2B1N A;  1AYW A;  3IUT A;  5JA7 A;  1DF0 A;  1GMY A;  4HWY A;  1AU3 A;  3V6C A;  2PAD A;  3HHI A;  1PPD A;  3PRP A;  2R9F A;  5A24 A;  4MZS A;  4REZ A;  5EZS A;  2OP3 A;  1PIP A;  3F75 A;  4BOS A;  1CVZ A;  4XUI A;  4WUR A;  5CVO B;  3PSE A;  2BTW B;  2AUZ A;  3PNR A;  4N4Z A;  2G6D A;  2FUD A;  4OEL A;  4BOQ A;  1QXP A;  1MIR A;  1YVB A;  4BOZ A;  2R9M A;  4ZTB A;  2Z84 A;  2E03 A;  1CSB B;  2NQG A;  4P6G A;  1A6R A;  2AVW A;  4YV8 A;  5FPW A;  2AU1 A;  1BGO A;  3ERV A;  1NQC A;  3PHU A;  1PPP A;  3S3Q A;  2FO5 A;  2DCB A;  1PCI A;  4BQV A;  4X6I A;  1NPZ A;  1MS6 A;  3DF0 A;  1SP4 B;  3IOQ A;  5CHT A;  2ACT A;  3H8C A;  3OIS A;  1KFX L;  3KKU A;  4Q8G A;  1PPO A;  3KWZ A;  3C0R A;  4KQT A;  2J7Q A;  2PBH A;  2FRQ A;  3LFY A;  4BOU A;  3K9M A;  1GLO A;  2F1G A;  4QBB A;  1DEU A;  2HXZ A;  3PBH A;  3O0U A;  1TU6 A;  3BPM A;  3OF8 A;  2DZY A;  4DMX A;  4YYS A;  3IEJ A;  2BDL A;  2XU1 A;  3D6S A;  3P5V A;  5K16 A;  4QH6 A;  1PBH A;  1SNK A;  2OZ2 A;  2R9C A;  5EZQ A;  3RNV A;  3BC3 A;  2BTW A;  3U8E A;  4OVZ B;  4ZUX U;  2UZJ A;  1U2M A;  2DJF B;  1M6D A;  3CBK A;  2R9N A;  1QOL A;  4BOP A;  4YYW A;  1MEM A;  4YVA A;  4KLB A;  4FK5 A;  3K8U A;  4GUA A;  4P6E A;  1K3B B;  2ATO A;  4AXM A;  3MHS A;  4XZX A;  4QRX A;  1PVJ A;  1PPN A;  3B21 A;  1NLJ A;  4IP3 A;  4N8W A;  3CH3 X;  4OEM A; 
#chains in the Genus database with same CATH homology
 4BOZ A;  3PHX A;  3TMP A;  4ZTB A;  2Z84 A;  2JRI A;  3BB7 A;  3PT2 A;  4A5U A;  4D8B A;  3BBA A;  4MI7 A;  2FE8 A;  3PHU A;  3O65 A;  1DKI A;  3BY4 A;  3OQC A;  1UKF A;  4HXD B;  4OW0 A;  3MTV A;  3PHW A;  3MJ5 A;  4M0W A;  3W30 A;  3ZNH A;  5JZE A;  4RKX A;  3W31 A;  3C0R A;  4P16 A;  4RF1 A;  4RNA A;  2AGA A;  3MP2 A;  2J7Q A;  2DOS A;  4BOU A;  2HWK A;  3TRK A;  3IFU A;  4RF0 A;  2J7Q C;  1YZB A;  2JTC A;  4OVZ A;  3PRP A;  4D8E A;  3E9S A;  4REZ A;  5EZQ A;  3RNV A;  5EZS A;  2BTW A;  4PT5 A;  4OVZ B;  4BOS A;  2UZJ A;  4WUR A;  2BU3 A;  4MM3 B;  4BOP A;  3PSE A;  5KO3 A;  2BTW B;  4GUA A;  4D8I A;  5E6J A;  4R3D A;  4XZX A;  4BOQ A;  4EVX A;  1PVJ A;  3B21 A;  4IP3 A;  4IUM A;  3PRM A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...