3BB7A

Structure of prevotella intermedia prointerpain a fragment 39-359 (mutant c154a)
Total Genus 89
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
321
structure length
314
Chain Sequence
ANQLRELKQTHTYTVFGYTDGGFAVISADDLAPELLGVSESNFVETDNPSFKWWLKAIDEVITNAVKSNKPLNVIKPDPSKYAAEVSTLLTTTWGQQMPYNKLLPKTKKGRLITGAVATATAQVLNYFKYPVRGIGSHTVHYPANDPSGVAISADFGNTTYDWANMKDNYSGNYTEAEANAVATLMLHCGVASEMQYGGPNEGSGAYMTDCAAGLRTYFGFTDAEYITRANYTDEQWMDIVFSELTKGHPLIYGGVDAGHAFVIDGYNKAGLVSVNWGWNGDVDGYYKIDLLNPGNMYSFTAEQDMVRGVYGKP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A
pubmed doi rcsb
molecule tags Hydrolase
source organism Prevotella intermedia
molecule keywords interpain A
total genus 89
structure length 314
sequence length 321
ec nomenclature
pdb deposition date 2007-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01640 Peptidase_C10 Peptidase C10 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.910.30 Alpha Beta 2-Layer Sandwich Protein Binding, DinI Protein; Chain A Protein Binding, DinI Protein; Chain A 3bb7A02
3.90.70.50 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cathepsin B; Chain A 3bb7A01
1DKIA 1PVJA 3BB7A 4D8IA 4D8BA 4D8EA 2JTCA 3BBAA 2UZJA 4RKXA
chains in the Genus database with same CATH superfamily
4G54A 2Y5BA 1Y4HA 1ICFA 4CZWA 2UZJA 2AYOA 4QRVA 3I06A 4RKXA 2E03A 3KSEA 2VHFA 2O6XA 2PADA 1U5IA 2B1MA 4ZUXU 3S3QA 1QMYA 5CVMA 1PBHA 3P5VA 4CDCB 2AU1A 3W30A 1MEMA 3GCBA 2DZZA 3RNVA 4PI3A 1TU6A 3IMAA 1CQDA 1QOLA 4OVZB 1PADA 1BY8A 2ARYA 3W31A 2DCCA 2DC8A 3P5WA 3MP2A 4OEMA 1POPA 1F2BA 1PE6A 1MHWA 3N3KA 4W5BA 3NHEA 2ATOA 2FYEA 4BQVA 2DJFB 3BPMA 4D8BA 2B1NA 2E00A 2YJCA 1CPJA 2AYNA 4CDFB 1CB5A 3ERVA 4WURA 1NQCA 4RF1A 2GHUA 2G8JA 2P7UA 4CDDB 4MM3B 6PADA 1NB3A 5CHTA 2OULA 4BS6A 2CIOA 3KWZA 1BP4A 3OF9A 3IUTA 4RNAA 3MHSA 2HD5A 4AXLA 1ZCMA 3MHHA 1DF0A 3ZUAA 4YYVA 5F02A 4YYUA 4YV8A 3F75A 3PNRA 1ZIVA 1S4VA 3RVVA 3PHUA 4QRGA 4N8WA 1UKFA 5JA7A 3B79A 1CJLA 3OVZA 2IPPB 1CVZA 3RVWA 2G6DA 2OP3A 1TL9A 2ACTA 2JQGR 2AUZA 4GUAA 4WA6A 1NLJA 1QDQA 1K3BB 2BTWB 4I07A 3KW9A 1U9XA 1TLOA 1CS8A 4W5CA 1PIPA 4N79A 2R9NA 1PCIA 5JH3A 1EWLA 5CVOB 2CB5A 2XU5A 1F2CA 3IHPA 2FO5A 1HUCB 1BGOA 1YZBA 4PADA 2DC6A 3BC3A 2R9CA 1GLOA 1YALA 1PPOA 4FK5A 4MSXA 3TNXA 3BWKA 2XU3A 2JTCA 1U9VA 4BPVA 2P86A 3HHAA 1KHPA 3DF0A 1AIMA 2DC9A 2AVWA 1F2AA 2BDZA 1AECA 3C9EA 5EZSA 2J7QA 3O65A 1AYWA 2YJ2A 2HWKA 1PPDA 2PBHA 4CDEB 4Q8HA 2DCDA 2YJBA 3PW3A 4OW0A 3BCNA 2HHNA 1SG2A 5EF4A 5KO3A 1EF7A 3M99A 4AXMA 1PPPA 4P6EA 3PT2A 3CH2X 3BB7A 1AU3A 1M6DA 2R9FA 3PRMA 1GECE 1KHQA 4YVAA 4FJCA 3F5VA 2E02A 1AYUA 4Q8GA 4DMYA 2J7QC 3H89A 5EGWA 4BOPA 1SP4B 2F7DA 1EWMA 9PAPA 4QRXA 1X9YA 1XKGA 1ITOA 4ZTBA 3OF8A 2H7JA 1CTEA 3QJ3A 4HWYA 1DEUA 5A24A 4N4ZA 2NQAA 2Z84A 5FPWA 2GFOA 4YYQA 3MJ5A 3MTVA 3BY4A 3PHXA 4BS5A 2DCAA 2JQFR 1CV8A 4R3DA 2XU1A 4A5UA 2VHSA 4RF0A 3KWBX 1AU4A 3LXSA 3N4CA 2AGAA 4KLBA 2DC7A 3CBJA 3HWNA 2FUDA 2FTDA 1U2MA 2DJGB 2E01A 2NQGA 2FRAA 4KQTA 2NQIA 2DOSA 1AYVA 1BQIA 3H8CA 1ATKA 3AI8A 4PP2E 2G7YA 3HHIA 1YT7A 1PPNA 1MIRA 3IV2A 3U8EA 2R6NA 5EZQA 3WXFA 4BOSA 2AUXA 1DKIA 1EWPA 1U9WA 2HH5A 1IWDA 2DZYA 2P0RA 4BOUA 2C0YA 3IOQA 4X6IA 3OISA 4DMXA 1SNKA 3BPFA 4P6GA 3QSDA 3D6SA 1MDWA 3O1GA 3V6EA 1ME4A 3HD3A 2R9OA 2HXZA 3MTNA 1PXVA 1Y08A 1KFXL 4MZOA 2BDLA 1ME3A 3KX1A 4IP3A 4BOZA 4PP1A 1NB5A 2Y6EA 5E6JA 3N3GA 1F29A 1AU0A 3TMPA 3IFUA 4HXDB 4QBBA 3LFYA 4M0WA 5CHVA 1MEGA 3PHWA 3CBKA 4YYWA 4D8IA 3RVXA 4W4UA 4X6JA 4XR7A 5CVNB 1THEA 4XUIA 3S3RA 4IUMA 2BU3A 1Q6KA 1STFE 4REZA 3ZNHA 8PCHA 3TRKA 1VSNA 1KXRA 3OVXA 3K8UA 3IEJA 2FQ9A 3PDFA 3I3TA 1EWOA 3C0RA 4X6HA 2G8EA 1U9QX 3P5XA 3O0UA 1QXPA 2IBIA 1YK7A 7PCKA 1GHHA 4QH6A 2BTWA 4BSQA 3BOWA 4MZSA 1AU2A 4BOQA 5J94A 4FIPA 1A6RA 1GMYA 2WBFX 3K9MA 4K7CA 4P16A 4YYRA 1FH0A 4EVXA 1NPZA 3P5UA 3V6CA 3WXEA 3MORA 2FT2A 3KFQA 4D8EA 3BBAA 2FRQA 2YJ8A 1YVBA 1O0EA 4RY2A 1PVJA 2R9MA 2AS8A 4I04A 3OQCA 2NQDB 3PRPA 2JRIA 5K16A 3PSEA 4XZXA 2FE8A 3E1ZB 4MI7A 1NL6A 4OELA 3H7DA 2DCBA 1JQPA 2F1GA 1CSBB 2PNSA 2YJ9A 4OVZA 1KFUL 2PREA 5JZEA 3E9SA 3QT4A 3PBHA 2XU4A 5PADA 1MS6A 3CH3X 3K24A 3USVA 3WXGA 4I05A 1GCBA 2AIMA 1YK8A 4PT5A 2OZ2A 3KKUA 3H6SA 3B21A 1VJVA 3H8BA 4YYSA
chains in the Genus database with same CATH topology
3MTVA 2BTWB 3BY4A 3PHXA 2UZJA 4R3DA 3C0RA 4A5UA 4RKXA 4RF0A 2AGAA 2BTWA 4BOQA 1YZBA 3W30A 3RNVA 4P16A 2DOSA 4OVZB 4EVXA 3W31A 4D8EA 2JTCA 3BBAA 5EZQA 3MP2A 4BOSA 1DKIA 1PVJA 5EZSA 2J7QA 4D8BA 3O65A 3OQCA 2HWKA 4BOUA 3MJ5A 3PRPA 4OW0A 2JRIA 4WURA 3PSEA 4RF1A 4XZXA 2FE8A 5KO3A 4MI7A 3PT2A 3BB7A 4MM3B 3PRMA 4IP3A 4BOZA 4OVZA 5E6JA 2J7QC 4RNAA 4BOPA 3TMPA 3IFUA 5JZEA 4HXDB 3E9SA 4M0WA 4ZTBA 3PHUA 3PHWA 1UKFA 4D8IA 4PT5A 4GUAA 2Z84A 3B21A 2BU3A 4IUMA 3ZNHA 4REZA 3TRKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DKI A;  1PVJ A;  3BB7 A;  4D8I A;  4D8B A;  4D8E A;  2JTC A;  3BBA A;  2UZJ A;  4RKX A; 
#chains in the Genus database with same CATH topology
 4G54 A;  2Y5B A;  1Y4H A;  1ICF A;  4CZW A;  2UZJ A;  2AYO A;  4QRV A;  3I06 A;  4RKX A;  2E03 A;  3KSE A;  2VHF A;  2O6X A;  2PAD A;  1U5I A;  2B1M A;  4ZUX U;  3S3Q A;  1QMY A;  5CVM A;  1PBH A;  3P5V A;  4CDC B;  2AU1 A;  3W30 A;  1MEM A;  3GCB A;  2DZZ A;  3RNV A;  4PI3 A;  1TU6 A;  3IMA A;  1CQD A;  1QOL A;  4OVZ B;  1PAD A;  1BY8 A;  2ARY A;  3W31 A;  2DCC A;  2DC8 A;  3P5W A;  3MP2 A;  4OEM A;  1POP A;  1F2B A;  1PE6 A;  1MHW A;  3N3K A;  4W5B A;  3NHE A;  2ATO A;  2FYE A;  4BQV A;  2DJF B;  3BPM A;  4D8B A;  2B1N A;  2E00 A;  2YJC A;  1CPJ A;  2AYN A;  4CDF B;  1CB5 A;  3ERV A;  4WUR A;  1NQC A;  4RF1 A;  2GHU A;  2G8J A;  2P7U A;  4CDD B;  4MM3 B;  6PAD A;  1NB3 A;  5CHT A;  2OUL A;  4BS6 A;  2CIO A;  3KWZ A;  1BP4 A;  3OF9 A;  3IUT A;  4RNA A;  3MHS A;  2HD5 A;  4AXL A;  1ZCM A;  3MHH A;  1DF0 A;  3ZUA A;  4YYV A;  5F02 A;  4YYU A;  4YV8 A;  3F75 A;  3PNR A;  1ZIV A;  1S4V A;  3RVV A;  3PHU A;  4QRG A;  4N8W A;  1UKF A;  5JA7 A;  3B79 A;  1CJL A;  3OVZ A;  2IPP B;  1CVZ A;  3RVW A;  2G6D A;  2OP3 A;  1TL9 A;  2ACT A;  2JQG R;  2AUZ A;  4GUA A;  4WA6 A;  1NLJ A;  1QDQ A;  1K3B B;  2BTW B;  4I07 A;  3KW9 A;  1U9X A;  1TLO A;  1CS8 A;  4W5C A;  1PIP A;  4N79 A;  2R9N A;  1PCI A;  5JH3 A;  1EWL A;  5CVO B;  2CB5 A;  2XU5 A;  1F2C A;  3IHP A;  2FO5 A;  1HUC B;  1BGO A;  1YZB A;  4PAD A;  2DC6 A;  3BC3 A;  2R9C A;  1GLO A;  1YAL A;  1PPO A;  4FK5 A;  4MSX A;  3TNX A;  3BWK A;  2XU3 A;  2JTC A;  1U9V A;  4BPV A;  2P86 A;  3HHA A;  1KHP A;  3DF0 A;  1AIM A;  2DC9 A;  2AVW A;  1F2A A;  2BDZ A;  1AEC A;  3C9E A;  5EZS A;  2J7Q A;  3O65 A;  1AYW A;  2YJ2 A;  2HWK A;  1PPD A;  2PBH A;  4CDE B;  4Q8H A;  2DCD A;  2YJB A;  3PW3 A;  4OW0 A;  3BCN A;  2HHN A;  1SG2 A;  5EF4 A;  5KO3 A;  1EF7 A;  3M99 A;  4AXM A;  1PPP A;  4P6E A;  3PT2 A;  3CH2 X;  3BB7 A;  1AU3 A;  1M6D A;  2R9F A;  3PRM A;  1GEC E;  1KHQ A;  4YVA A;  4FJC A;  3F5V A;  2E02 A;  1AYU A;  4Q8G A;  4DMY A;  2J7Q C;  3H89 A;  5EGW A;  4BOP A;  1SP4 B;  2F7D A;  1EWM A;  9PAP A;  4QRX A;  1X9Y A;  1XKG A;  1ITO A;  4ZTB A;  3OF8 A;  2H7J A;  1CTE A;  3QJ3 A;  4HWY A;  1DEU A;  5A24 A;  4N4Z A;  2NQA A;  2Z84 A;  5FPW A;  2GFO A;  4YYQ A;  3MJ5 A;  3MTV A;  3BY4 A;  3PHX A;  4BS5 A;  2DCA A;  2JQF R;  1CV8 A;  4R3D A;  2XU1 A;  4A5U A;  2VHS A;  4RF0 A;  3KWB X;  1AU4 A;  3LXS A;  3N4C A;  2AGA A;  4KLB A;  2DC7 A;  3CBJ A;  3HWN A;  2FUD A;  2FTD A;  1U2M A;  2DJG B;  2E01 A;  2NQG A;  2FRA A;  4KQT A;  2NQI A;  2DOS A;  1AYV A;  1BQI A;  3H8C A;  1ATK A;  3AI8 A;  4PP2 E;  2G7Y A;  3HHI A;  1YT7 A;  1PPN A;  1MIR A;  3IV2 A;  3U8E A;  2R6N A;  5EZQ A;  3WXF A;  4BOS A;  2AUX A;  1DKI A;  1EWP A;  1U9W A;  2HH5 A;  1IWD A;  2DZY A;  2P0R A;  4BOU A;  2C0Y A;  3IOQ A;  4X6I A;  3OIS A;  4DMX A;  1SNK A;  3BPF A;  4P6G A;  3QSD A;  3D6S A;  1MDW A;  3O1G A;  3V6E A;  1ME4 A;  3HD3 A;  2R9O A;  2HXZ A;  3MTN A;  1PXV A;  1Y08 A;  1KFX L;  4MZO A;  2BDL A;  1ME3 A;  3KX1 A;  4IP3 A;  4BOZ A;  4PP1 A;  1NB5 A;  2Y6E A;  5E6J A;  3N3G A;  1F29 A;  1AU0 A;  3TMP A;  3IFU A;  4HXD B;  4QBB A;  3LFY A;  4M0W A;  5CHV A;  1MEG A;  3PHW A;  3CBK A;  4YYW A;  4D8I A;  3RVX A;  4W4U A;  4X6J A;  4XR7 A;  5CVN B;  1THE A;  4XUI A;  3S3R A;  4IUM A;  2BU3 A;  1Q6K A;  1STF E;  4REZ A;  3ZNH A;  8PCH A;  3TRK A;  1VSN A;  1KXR A;  3OVX A;  3K8U A;  3IEJ A;  2FQ9 A;  3PDF A;  3I3T A;  1EWO A;  3C0R A;  4X6H A;  2G8E A;  1U9Q X;  3P5X A;  3O0U A;  1QXP A;  2IBI A;  1YK7 A;  7PCK A;  1GHH A;  4QH6 A;  2BTW A;  4BSQ A;  3BOW A;  4MZS A;  1AU2 A;  4BOQ A;  5J94 A;  4FIP A;  1A6R A;  1GMY A;  2WBF X;  3K9M A;  4K7C A;  4P16 A;  4YYR A;  1FH0 A;  4EVX A;  1NPZ A;  3P5U A;  3V6C A;  3WXE A;  3MOR A;  2FT2 A;  3KFQ A;  4D8E A;  3BBA A;  2FRQ A;  2YJ8 A;  1YVB A;  1O0E A;  4RY2 A;  1PVJ A;  2R9M A;  2AS8 A;  4I04 A;  3OQC A;  2NQD B;  3PRP A;  2JRI A;  5K16 A;  3PSE A;  4XZX A;  2FE8 A;  3E1Z B;  4MI7 A;  1NL6 A;  4OEL A;  3H7D A;  2DCB A;  1JQP A;  2F1G A;  1CSB B;  2PNS A;  2YJ9 A;  4OVZ A;  1KFU L;  2PRE A;  5JZE A;  3E9S A;  3QT4 A;  3PBH A;  2XU4 A;  5PAD A;  1MS6 A;  3CH3 X;  3K24 A;  3USV A;  3WXG A;  4I05 A;  1GCB A;  2AIM A;  1YK8 A;  4PT5 A;  2OZ2 A;  3KKU A;  3H6S A;  3B21 A;  1VJV A;  3H8B A;  4YYS A; 
#chains in the Genus database with same CATH homology
 3MTV A;  2BTW B;  3BY4 A;  3PHX A;  2UZJ A;  4R3D A;  3C0R A;  4A5U A;  4RKX A;  4RF0 A;  2AGA A;  2BTW A;  4BOQ A;  1YZB A;  3W30 A;  3RNV A;  4P16 A;  2DOS A;  4OVZ B;  4EVX A;  3W31 A;  4D8E A;  2JTC A;  3BBA A;  5EZQ A;  3MP2 A;  4BOS A;  1DKI A;  1PVJ A;  5EZS A;  2J7Q A;  4D8B A;  3O65 A;  3OQC A;  2HWK A;  4BOU A;  3MJ5 A;  3PRP A;  4OW0 A;  2JRI A;  4WUR A;  3PSE A;  4RF1 A;  4XZX A;  2FE8 A;  5KO3 A;  4MI7 A;  3PT2 A;  3BB7 A;  4MM3 B;  3PRM A;  4IP3 A;  4BOZ A;  4OVZ A;  5E6J A;  2J7Q C;  4RNA A;  4BOP A;  3TMP A;  3IFU A;  5JZE A;  4HXD B;  3E9S A;  4M0W A;  4ZTB A;  3PHU A;  3PHW A;  1UKF A;  4D8I A;  4PT5 A;  4GUA A;  2Z84 A;  3B21 A;  2BU3 A;  4IUM A;  3ZNH A;  4REZ A;  3TRK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...