1AU3A

Crystal structure of the cysteine protease human cathepsin k in complex with a covalent pyrrolidinone inhibitor
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformationally constrained 1,3-diamino ketones: a series of potent inhibitors of the cysteine protease cathepsin K.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CATHEPSIN K
total genus 60
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 1997-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1au3A00
2NQAA 1PPDA 3HHIA 1CTEA 3IUTA 1MIRA 1MEGA 1Q6KA 3P5VA 3HD3A 2PADA 1TLOA 2GFOA 3IV2A 1MEMA 3KFQA 2ACTA 3N4CA 2AUZA 2R6NA 1VJVA 2DZYA 2G7YA 4P6EA 3PNRA 3U8EA 3LFYA 1Y4HA 3MORA 5A24A 3KX1A 3BC3A 3TNXA 1CJLA 3H7DA 3H8BA 2PREA 2R9MA 3K24A 1EWMA 2AYNA 1ME4A 3PW3A 1STFE 5JH3A 3KWZA 4MZOA 1PPPA 2FQ9A 4QRVA 8PCHA 4KLBA 1U5IA 4W4UA 1K3BB 4XR7A 4QRGA 3ERVA 4BSQA 1EF7A 4DMYA 2FRAA 2R9FA 3OVZA 4PP2E 2G6DA 2JQGR 3V6CA 4RY2A 4N4ZA 4YYUA 1NB3A 1BGOA 1F29A 3CBJA 4PADA 3C9EA 1DEUA 2DCAA 1AU4A 4CDCB 1CQDA 5CVMA 2YJ8A 1YALA 1NL6A 2FRQA 6PADA 3S3QA 1CPJA 1JQPA 1AYVA 3IOQA 2P86A 1CS8A 1AYWA 1MDWA 4N79A 1M6DA 2VHFA 1KFXL 2XU3A 2XU4A 1GLOA 1YK7A 2B1NA 2P7UA 2CIOA 4YYQA 1GMYA 4PI3A 1MS6A 2DC8A 3OF8A 2DJFB 5FPWA 1IWDA 1O0EA 4I07A 2FO5A 5J94A 4WA6A 5K16A 2AS8A 3E1ZB 1PADA 4ZUXU 1FH0A 3F75A 2JQFR 3USVA 3RVWA 1PCIA 2Y5BA 3QT4A 1PPOA 2FUDA 4FK5A 1Y08A 1AIMA 3MHHA 2DCCA 1HUCB 1KHQA 3F5VA 1BY8A 1AECA 1ATKA 3CBKA 1ZCMA 2FT2A 1CSBB 2DJGB 4XUIA 4CDFB 3N3GA 2AYOA 3I3TA 3QSDA 2FYEA 4OELA 2BDZA 3P5UA 1EWLA 3D6SA 9PAPA 4X6IA 4BS5A 2G8JA 2YJBA 3O0UA 4QH6A 1BP4A 2ARYA 1THEA 3H6SA 3KW9A 3V6EA 4AXLA 1ZIVA 4AXMA 2VHSA 3OVXA 4CZWA 3ZUAA 3OF9A 2HHNA 3B79A 1AU2A 3CH3X 2Y6EA 1PIPA 3PDFA 3P5WA 5CVNB 3O1GA 1QDQA 4YYSA 2NQDB 4YV8A 4X6JA 1U9VA 1POPA 7PCKA 2H7JA 4MSXA 4MZSA 1TL9A 3RVVA 2YJCA 4CDEB 2C0YA 1GCBA 2XU1A 1CV8A 1F2BA 2YJ2A 3MTNA 4FIPA 1TU6A 4YYVA 1A6RA 1AU3A 2OZ2A 2FTDA 4I04A 4HWYA 3CH2X 3K9MA 3P5XA 4W5BA 3HWNA 2E01A 1F2AA 1BQIA 3PBHA 2OULA 4CDDB 3IEJA 3AI8A 5EF4A 2G8EA 1XKGA 2F7DA 2P0RA 3NHEA 4X6HA 3KWBX 3BPFA 4N8WA 1EWPA 4P6GA 1U9QX 3BPMA 2DC6A 5JA7A 3WXEA 2CB5A 3BWKA 5CVOB 1NQCA 1YK8A 2HH5A 3M99A 1NPZA 3H89A 3QJ3A 1SNKA 3BOWA 2NQIA 1KXRA 3IHPA 3S3RA 5CHVA 4YYRA 2R9NA 2BDLA 1QXPA 2HD5A 4K7CA 3LXSA 1QOLA 3KKUA 3RVXA 1PPNA 2AVWA 1F2CA 2AUXA 5F02A 1NLJA 1CVZA 3BCNA 1X9YA 4BPVA 3HHAA 1PE6A 1GECE 4YYWA 4I05A 2PBHA 2DC7A 2IBIA 2NQGA 3OISA 4BS6A 2E03A 4FJCA 1KHPA 5CHTA 2O6XA 3N3KA 1MHWA 5PADA 2WBFX 3IMAA 2OP3A 1AU0A 2F1GA 2HXZA 1EWOA 3WXGA 2DCDA 4YVAA 1ITOA 2YJ9A 4PP1A 2IPPB 5EGWA 2GHUA 3WXFA 2AIMA 2DZZA 1ICFA 1CB5A 1SP4B 4G54A 1S4VA 2AU1A 3H8CA 2R9CA 1KFUL 1YT7A 4QBBA 2ATOA 2E02A 3I06A 3K8UA 1ME3A 3GCBA 3KSEA 1YVBA 4Q8HA 1PXVA 4DMXA 1AYUA 2B1MA 1NB5A 1QMYA 2PNSA 2XU5A 1U9WA 2DCBA 4W5CA 1U9XA 4OEMA 1DF0A 4BQVA 4QRXA 3DF0A 1VSNA 2R9OA 3MHSA 2E00A 1PBHA 4Q8GA 2DC9A
chains in the Genus database with same CATH superfamily
3MP2A 2NQAA 1PPDA 3HHIA 1CTEA 5EZSA 3C0RA 3IUTA 1MIRA 1MEGA 1Q6KA 3P5VA 3HD3A 2PADA 1TLOA 2GFOA 4D8IA 3IV2A 1MEMA 3KFQA 2ACTA 3N4CA 2AUZA 2R6NA 1VJVA 2DZYA 2G7YA 4P6EA 3PNRA 4XZXA 3PRMA 3U8EA 3LFYA 1Y4HA 3MORA 5A24A 3KX1A 3BC3A 3PT2A 3TNXA 1CJLA 3H7DA 1DKIA 3PHXA 3H8BA 2PREA 2R9MA 3K24A 2BTWA 1EWMA 1YZBA 2AYNA 4PT5A 1ME4A 3PW3A 1STFE 4HXDB 3KWZA 4MZOA 5JH3A 1PPPA 2FQ9A 4QRVA 8PCHA 4KLBA 1U5IA 4W4UA 1K3BB 4XR7A 4QRGA 3ERVA 4IUMA 4BSQA 4BOSA 1EF7A 4MI7A 4REZA 4DMYA 2FRAA 2J7QA 2R9FA 3OVZA 4PP2E 2G6DA 2JQGR 3V6CA 4RY2A 4N4ZA 4YYUA 1NB3A 1BGOA 1F29A 3CBJA 4PADA 3C9EA 1DEUA 3OQCA 2DCAA 1AU4A 4CDCB 1CQDA 5CVMA 2YJ8A 1YALA 1NL6A 2FRQA 6PADA 3S3QA 1CPJA 1JQPA 1AYVA 3IOQA 2P86A 1CS8A 1AYWA 2AGAA 3W30A 1MDWA 4N79A 1M6DA 4OVZB 2VHFA 2J7QC 4RF0A 3MTVA 1KFXL 2XU3A 2XU4A 1GLOA 1YK7A 2B1NA 2P7UA 2CIOA 4BOPA 4YYQA 1GMYA 4PI3A 3ZNHA 1MS6A 2DC8A 3OF8A 2DJFB 5FPWA 1IWDA 1O0EA 4I07A 2FO5A 5J94A 5EZQA 4WA6A 5K16A 2AS8A 3E1ZB 1PADA 4D8EA 4M0WA 3B21A 4OW0A 4ZUXU 1FH0A 3F75A 2JQFR 4GUAA 3RVWA 3USVA 1PCIA 2Y5BA 3QT4A 1PPOA 2FUDA 4FK5A 1Y08A 1AIMA 3MHHA 2DCCA 1HUCB 1KHQA 5E6JA 3F5VA 1BY8A 1AECA 1ATKA 3CBKA 1ZCMA 2FT2A 1CSBB 2DJGB 3PSEA 4XUIA 4CDFB 3N3GA 2AYOA 3I3TA 3QSDA 2FYEA 4RKXA 4OELA 2BDZA 3P5UA 1EWLA 3D6SA 3PRPA 9PAPA 4X6IA 4BS5A 2G8JA 2YJBA 3O0UA 4QH6A 1BP4A 2ARYA 1THEA 3PHWA 3H6SA 3KW9A 3V6EA 4AXLA 1ZIVA 4AXMA 3TMPA 2VHSA 3PHUA 3OVXA 4CZWA 3MJ5A 3ZUAA 3OF9A 2HHNA 3B79A 1AU2A 3CH3X 2Y6EA 1PIPA 3PDFA 3P5WA 5CVNB 3O1GA 4BOZA 3TRKA 1QDQA 4MM3B 4YYSA 2NQDB 4YV8A 4X6JA 1U9VA 1POPA 7PCKA 2H7JA 4RNAA 4MSXA 2HWKA 3W31A 4MZSA 4P16A 2FE8A 1TL9A 3RVVA 2YJCA 4CDEB 2C0YA 1GCBA 2XU1A 1CV8A 3BBAA 1F2BA 2YJ2A 3MTNA 4FIPA 1TU6A 4YYVA 5JZEA 1A6RA 1AU3A 2OZ2A 2FTDA 4I04A 4HWYA 2BTWB 3CH2X 3K9MA 3P5XA 4W5BA 3RNVA 3HWNA 2E01A 1F2AA 1BQIA 3O65A 3PBHA 2OULA 4CDDB 3IEJA 3AI8A 5EF4A 2G8EA 1XKGA 2F7DA 2P0RA 3NHEA 4X6HA 3KWBX 3BPFA 4N8WA 1EWPA 4P6GA 1U9QX 3BPMA 2DC6A 5KO3A 5JA7A 3WXEA 2CB5A 3BWKA 5CVOB 1NQCA 1YK8A 2HH5A 3M99A 1NPZA 3H89A 3QJ3A 4R3DA 1SNKA 3BOWA 2NQIA 1KXRA 3IHPA 3S3RA 5CHVA 4YYRA 2R9NA 2BDLA 1QXPA 2HD5A 4K7CA 2Z84A 3LXSA 1QOLA 3KKUA 4BOUA 3RVXA 1UKFA 1PPNA 4RF1A 2AVWA 1F2CA 2AUXA 4OVZA 5F02A 1NLJA 4BOQA 1CVZA 3BCNA 1X9YA 3E9SA 4BPVA 3HHAA 1PE6A 1GECE 4YYWA 4I05A 2PBHA 4D8BA 2DC7A 2IBIA 2NQGA 3OISA 3IFUA 4BS6A 4A5UA 2BU3A 2E03A 4FJCA 1KHPA 5CHTA 2DOSA 2O6XA 3N3KA 1MHWA 5PADA 2WBFX 3BY4A 3IMAA 2OP3A 1AU0A 2F1GA 2HXZA 1EWOA 3WXGA 2DCDA 4YVAA 1ITOA 2YJ9A 4PP1A 2IPPB 3BB7A 5EGWA 2GHUA 3WXFA 2AIMA 2DZZA 4ZTBA 1ICFA 1CB5A 2JTCA 1SP4B 4G54A 1S4VA 2AU1A 3H8CA 4IP3A 2R9CA 1KFUL 1PVJA 1YT7A 4QBBA 2ATOA 2E02A 3I06A 3K8UA 2JRIA 1ME3A 3GCBA 3KSEA 1YVBA 4Q8HA 1PXVA 4WURA 4DMXA 1AYUA 2B1MA 1NB5A 1QMYA 2PNSA 2XU5A 1U9WA 2DCBA 2UZJA 4W5CA 1U9XA 4OEMA 1DF0A 4BQVA 4QRXA 3DF0A 1VSNA 2R9OA 3MHSA 2E00A 1PBHA 4Q8GA 2DC9A
chains in the Genus database with same CATH topology
2NQAA 1PPDA 3HHIA 1CTEA 3IUTA 1MIRA 1MEGA 1Q6KA 3P5VA 3HD3A 2PADA 1TLOA 2GFOA 3IV2A 1MEMA 3KFQA 2ACTA 3N4CA 2AUZA 2R6NA 1VJVA 2DZYA 2G7YA 4P6EA 3PNRA 3U8EA 3LFYA 1Y4HA 3MORA 5A24A 3KX1A 3BC3A 3D9WA 3TNXA 1CJLA 3H7DA 2VFBA 3H8BA 2PREA 2R9MA 3K24A 1EWMA 2AYNA 1ME4A 3PW3A 1STFE 5JH3A 3KWZA 4MZOA 1PPPA 4BGFA 2FQ9A 4QRVA 8PCHA 4KLBA 1U5IA 4W4UA 1K3BB 4XR7A 4QRGA 3ERVA 4BSQA 1EF7A 4DMYA 2FRAA 2R9FA 3OVZA 4PP2E 1GX3A 2G6DA 2JQGR 3V6CA 4RY2A 4N4ZA 4YYUA 1NB3A 1BGOA 1F29A 3LTWA 3CBJA 4PADA 3C9EA 1DEUA 2DCAA 1AU4A 4CDCB 1CQDA 5CVMA 2YJ8A 1YALA 1NL6A 2FRQA 6PADA 3S3QA 1CPJA 1JQPA 1AYVA 3IOQA 4GUZA 2P86A 1CS8A 1AYWA 1MDWA 4N79A 1M6DA 2VHFA 1KFXL 2XU3A 2XU4A 1GLOA 1YK7A 2B1NA 2P7UA 2CIOA 4YYQA 1GMYA 4PI3A 1MS6A 2DC8A 4NV7A 3OF8A 2DJFB 5FPWA 1IWDA 1O0EA 4I07A 2FO5A 5J94A 4WA6A 5K16A 2AS8A 2BSZA 3E1ZB 1PADA 4C5PA 4ZUXU 1FH0A 4B55A 3F75A 2JQFR 3USVA 3RVWA 1PCIA 4NV8A 2Y5BA 3QT4A 1PPOA 2FUDA 4FK5A 1Y08A 1AIMA 3MHHA 2DCCA 1HUCB 1KHQA 3F5VA 1BY8A 1AECA 1ATKA 3CBKA 1ZCMA 2FT2A 1CSBB 2DJGB 4XUIA 4CDFB 3N3GA 2AYOA 3I3TA 3QSDA 2FYEA 4OELA 2BDZA 3P5UA 1EWLA 3D6SA 9PAPA 4X6IA 4BS5A 2G8JA 2YJBA 3O0UA 4QH6A 1BP4A 2ARYA 1THEA 3H6SA 3KW9A 3V6EA 4AXLA 1ZIVA 4AXMA 2VHSA 3OVXA 4CZWA 1W6FA 3ZUAA 3OF9A 2HHNA 3B79A 1AU2A 3CH3X 2Y6EA 1PIPA 3PDFA 3P5WA 5CVNB 3O1GA 1QDQA 4YYSA 2NQDB 4YV8A 4X6JA 1U9VA 1POPA 7PCKA 2H7JA 4MSXA 4MZSA 1TL9A 3RVVA 2YJCA 4CDEB 2C0YA 1GCBA 2XU1A 1E2TA 1CV8A 1F2BA 2YJ2A 3MTNA 4FIPA 1TU6A 4YYVA 1A6RA 1AU3A 2OZ2A 2FTDA 4I04A 4HWYA 3CH2X 3K9MA 3P5XA 4W5BA 3HWNA 2E01A 1F2AA 1BQIA 3PBHA 2OULA 4CDDB 3IEJA 3AI8A 1W5RA 1W4TA 5EF4A 2G8EA 1XKGA 2F7DA 2P0RA 3NHEA 2VFCA 4X6HA 3KWBX 3BPFA 4N8WA 1EWPA 4P6GA 1U9QX 3BPMA 2DC6A 5JA7A 3WXEA 2CB5A 3BWKA 5CVOB 1NQCA 1YK8A 2HH5A 3M99A 1NPZA 3H89A 3QJ3A 1SNKA 3BOWA 2NQIA 1KXRA 3IHPA 3S3RA 5CHVA 4YYRA 2R9NA 2BDLA 1QXPA 2HD5A 4K7CA 3LXSA 1QOLA 3KKUA 3RVXA 1PPNA 2AVWA 1F2CA 2AUXA 5F02A 1NLJA 1CVZA 3BCNA 1X9YA 4BPVA 3HHAA 1PE6A 1GECE 4YYWA 4I05A 2PBHA 2DC7A 2IBIA 2NQGA 3OISA 4BS6A 2E03A 4FJCA 1KHPA 5CHTA 2O6XA 3N3KA 1MHWA 5PADA 2WBFX 3IMAA 2OP3A 1AU0A 2F1GA 2HXZA 1EWOA 3WXGA 2DCDA 4YVAA 1ITOA 2YJ9A 4PP1A 2IPPB 5EGWA 2GHUA 3WXFA 2AIMA 2DZZA 1ICFA 1CB5A 1SP4B 4G54A 1S4VA 2AU1A 3H8CA 2R9CA 1KFUL 1YT7A 4QBBA 2ATOA 2E02A 3I06A 3K8UA 1ME3A 3GCBA 3KSEA 1YVBA 4Q8HA 1PXVA 4DMXA 1AYUA 2B1MA 1NB5A 1QMYA 2PNSA 2XU5A 1U9WA 2DCBA 4W5CA 1U9XA 4OEMA 1DF0A 4BQVA 4QRXA 3DF0A 1VSNA 2R9OA 3MHSA 2E00A 1PBHA 4Q8GA 2DC9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NQA A;  1PPD A;  3HHI A;  1CTE A;  3IUT A;  1MIR A;  1MEG A;  1Q6K A;  3P5V A;  3HD3 A;  2PAD A;  1TLO A;  2GFO A;  3IV2 A;  1MEM A;  3KFQ A;  2ACT A;  3N4C A;  2AUZ A;  2R6N A;  1VJV A;  2DZY A;  2G7Y A;  4P6E A;  3PNR A;  3U8E A;  3LFY A;  1Y4H A;  3MOR A;  5A24 A;  3KX1 A;  3BC3 A;  3TNX A;  1CJL A;  3H7D A;  3H8B A;  2PRE A;  2R9M A;  3K24 A;  1EWM A;  2AYN A;  1ME4 A;  3PW3 A;  1STF E;  5JH3 A;  3KWZ A;  4MZO A;  1PPP A;  2FQ9 A;  4QRV A;  8PCH A;  4KLB A;  1U5I A;  4W4U A;  1K3B B;  4XR7 A;  4QRG A;  3ERV A;  4BSQ A;  1EF7 A;  4DMY A;  2FRA A;  2R9F A;  3OVZ A;  4PP2 E;  2G6D A;  2JQG R;  3V6C A;  4RY2 A;  4N4Z A;  4YYU A;  1NB3 A;  1BGO A;  1F29 A;  3CBJ A;  4PAD A;  3C9E A;  1DEU A;  2DCA A;  1AU4 A;  4CDC B;  1CQD A;  5CVM A;  2YJ8 A;  1YAL A;  1NL6 A;  2FRQ A;  6PAD A;  3S3Q A;  1CPJ A;  1JQP A;  1AYV A;  3IOQ A;  2P86 A;  1CS8 A;  1AYW A;  1MDW A;  4N79 A;  1M6D A;  2VHF A;  1KFX L;  2XU3 A;  2XU4 A;  1GLO A;  1YK7 A;  2B1N A;  2P7U A;  2CIO A;  4YYQ A;  1GMY A;  4PI3 A;  1MS6 A;  2DC8 A;  3OF8 A;  2DJF B;  5FPW A;  1IWD A;  1O0E A;  4I07 A;  2FO5 A;  5J94 A;  4WA6 A;  5K16 A;  2AS8 A;  3E1Z B;  1PAD A;  4ZUX U;  1FH0 A;  3F75 A;  2JQF R;  3USV A;  3RVW A;  1PCI A;  2Y5B A;  3QT4 A;  1PPO A;  2FUD A;  4FK5 A;  1Y08 A;  1AIM A;  3MHH A;  2DCC A;  1HUC B;  1KHQ A;  3F5V A;  1BY8 A;  1AEC A;  1ATK A;  3CBK A;  1ZCM A;  2FT2 A;  1CSB B;  2DJG B;  4XUI A;  4CDF B;  3N3G A;  2AYO A;  3I3T A;  3QSD A;  2FYE A;  4OEL A;  2BDZ A;  3P5U A;  1EWL A;  3D6S A;  9PAP A;  4X6I A;  4BS5 A;  2G8J A;  2YJB A;  3O0U A;  4QH6 A;  1BP4 A;  2ARY A;  1THE A;  3H6S A;  3KW9 A;  3V6E A;  4AXL A;  1ZIV A;  4AXM A;  2VHS A;  3OVX A;  4CZW A;  3ZUA A;  3OF9 A;  2HHN A;  3B79 A;  1AU2 A;  3CH3 X;  2Y6E A;  1PIP A;  3PDF A;  3P5W A;  5CVN B;  3O1G A;  1QDQ A;  4YYS A;  2NQD B;  4YV8 A;  4X6J A;  1U9V A;  1POP A;  7PCK A;  2H7J A;  4MSX A;  4MZS A;  1TL9 A;  3RVV A;  2YJC A;  4CDE B;  2C0Y A;  1GCB A;  2XU1 A;  1CV8 A;  1F2B A;  2YJ2 A;  3MTN A;  4FIP A;  1TU6 A;  4YYV A;  1A6R A;  1AU3 A;  2OZ2 A;  2FTD A;  4I04 A;  4HWY A;  3CH2 X;  3K9M A;  3P5X A;  4W5B A;  3HWN A;  2E01 A;  1F2A A;  1BQI A;  3PBH A;  2OUL A;  4CDD B;  3IEJ A;  3AI8 A;  5EF4 A;  2G8E A;  1XKG A;  2F7D A;  2P0R A;  3NHE A;  4X6H A;  3KWB X;  3BPF A;  4N8W A;  1EWP A;  4P6G A;  1U9Q X;  3BPM A;  2DC6 A;  5JA7 A;  3WXE A;  2CB5 A;  3BWK A;  5CVO B;  1NQC A;  1YK8 A;  2HH5 A;  3M99 A;  1NPZ A;  3H89 A;  3QJ3 A;  1SNK A;  3BOW A;  2NQI A;  1KXR A;  3IHP A;  3S3R A;  5CHV A;  4YYR A;  2R9N A;  2BDL A;  1QXP A;  2HD5 A;  4K7C A;  3LXS A;  1QOL A;  3KKU A;  3RVX A;  1PPN A;  2AVW A;  1F2C A;  2AUX A;  5F02 A;  1NLJ A;  1CVZ A;  3BCN A;  1X9Y A;  4BPV A;  3HHA A;  1PE6 A;  1GEC E;  4YYW A;  4I05 A;  2PBH A;  2DC7 A;  2IBI A;  2NQG A;  3OIS A;  4BS6 A;  2E03 A;  4FJC A;  1KHP A;  5CHT A;  2O6X A;  3N3K A;  1MHW A;  5PAD A;  2WBF X;  3IMA A;  2OP3 A;  1AU0 A;  2F1G A;  2HXZ A;  1EWO A;  3WXG A;  2DCD A;  4YVA A;  1ITO A;  2YJ9 A;  4PP1 A;  2IPP B;  5EGW A;  2GHU A;  3WXF A;  2AIM A;  2DZZ A;  1ICF A;  1CB5 A;  1SP4 B;  4G54 A;  1S4V A;  2AU1 A;  3H8C A;  2R9C A;  1KFU L;  1YT7 A;  4QBB A;  2ATO A;  2E02 A;  3I06 A;  3K8U A;  1ME3 A;  3GCB A;  3KSE A;  1YVB A;  4Q8H A;  1PXV A;  4DMX A;  1AYU A;  2B1M A;  1NB5 A;  1QMY A;  2PNS A;  2XU5 A;  1U9W A;  2DCB A;  4W5C A;  1U9X A;  4OEM A;  1DF0 A;  4BQV A;  4QRX A;  3DF0 A;  1VSN A;  2R9O A;  3MHS A;  2E00 A;  1PBH A;  4Q8G A;  2DC9 A; 
#chains in the Genus database with same CATH topology
 3MP2 A;  2NQA A;  1PPD A;  3HHI A;  1CTE A;  5EZS A;  3C0R A;  3IUT A;  1MIR A;  1MEG A;  1Q6K A;  3P5V A;  3HD3 A;  2PAD A;  1TLO A;  2GFO A;  4D8I A;  3IV2 A;  1MEM A;  3KFQ A;  2ACT A;  3N4C A;  2AUZ A;  2R6N A;  1VJV A;  2DZY A;  2G7Y A;  4P6E A;  3PNR A;  4XZX A;  3PRM A;  3U8E A;  3LFY A;  1Y4H A;  3MOR A;  5A24 A;  3KX1 A;  3BC3 A;  3PT2 A;  3TNX A;  1CJL A;  3H7D A;  1DKI A;  3PHX A;  3H8B A;  2PRE A;  2R9M A;  3K24 A;  2BTW A;  1EWM A;  1YZB A;  2AYN A;  4PT5 A;  1ME4 A;  3PW3 A;  1STF E;  4HXD B;  3KWZ A;  4MZO A;  5JH3 A;  1PPP A;  2FQ9 A;  4QRV A;  8PCH A;  4KLB A;  1U5I A;  4W4U A;  1K3B B;  4XR7 A;  4QRG A;  3ERV A;  4IUM A;  4BSQ A;  4BOS A;  1EF7 A;  4MI7 A;  4REZ A;  4DMY A;  2FRA A;  2J7Q A;  2R9F A;  3OVZ A;  4PP2 E;  2G6D A;  2JQG R;  3V6C A;  4RY2 A;  4N4Z A;  4YYU A;  1NB3 A;  1BGO A;  1F29 A;  3CBJ A;  4PAD A;  3C9E A;  1DEU A;  3OQC A;  2DCA A;  1AU4 A;  4CDC B;  1CQD A;  5CVM A;  2YJ8 A;  1YAL A;  1NL6 A;  2FRQ A;  6PAD A;  3S3Q A;  1CPJ A;  1JQP A;  1AYV A;  3IOQ A;  2P86 A;  1CS8 A;  1AYW A;  2AGA A;  3W30 A;  1MDW A;  4N79 A;  1M6D A;  4OVZ B;  2VHF A;  2J7Q C;  4RF0 A;  3MTV A;  1KFX L;  2XU3 A;  2XU4 A;  1GLO A;  1YK7 A;  2B1N A;  2P7U A;  2CIO A;  4BOP A;  4YYQ A;  1GMY A;  4PI3 A;  3ZNH A;  1MS6 A;  2DC8 A;  3OF8 A;  2DJF B;  5FPW A;  1IWD A;  1O0E A;  4I07 A;  2FO5 A;  5J94 A;  5EZQ A;  4WA6 A;  5K16 A;  2AS8 A;  3E1Z B;  1PAD A;  4D8E A;  4M0W A;  3B21 A;  4OW0 A;  4ZUX U;  1FH0 A;  3F75 A;  2JQF R;  4GUA A;  3RVW A;  3USV A;  1PCI A;  2Y5B A;  3QT4 A;  1PPO A;  2FUD A;  4FK5 A;  1Y08 A;  1AIM A;  3MHH A;  2DCC A;  1HUC B;  1KHQ A;  5E6J A;  3F5V A;  1BY8 A;  1AEC A;  1ATK A;  3CBK A;  1ZCM A;  2FT2 A;  1CSB B;  2DJG B;  3PSE A;  4XUI A;  4CDF B;  3N3G A;  2AYO A;  3I3T A;  3QSD A;  2FYE A;  4RKX A;  4OEL A;  2BDZ A;  3P5U A;  1EWL A;  3D6S A;  3PRP A;  9PAP A;  4X6I A;  4BS5 A;  2G8J A;  2YJB A;  3O0U A;  4QH6 A;  1BP4 A;  2ARY A;  1THE A;  3PHW A;  3H6S A;  3KW9 A;  3V6E A;  4AXL A;  1ZIV A;  4AXM A;  3TMP A;  2VHS A;  3PHU A;  3OVX A;  4CZW A;  3MJ5 A;  3ZUA A;  3OF9 A;  2HHN A;  3B79 A;  1AU2 A;  3CH3 X;  2Y6E A;  1PIP A;  3PDF A;  3P5W A;  5CVN B;  3O1G A;  4BOZ A;  3TRK A;  1QDQ A;  4MM3 B;  4YYS A;  2NQD B;  4YV8 A;  4X6J A;  1U9V A;  1POP A;  7PCK A;  2H7J A;  4RNA A;  4MSX A;  2HWK A;  3W31 A;  4MZS A;  4P16 A;  2FE8 A;  1TL9 A;  3RVV A;  2YJC A;  4CDE B;  2C0Y A;  1GCB A;  2XU1 A;  1CV8 A;  3BBA A;  1F2B A;  2YJ2 A;  3MTN A;  4FIP A;  1TU6 A;  4YYV A;  5JZE A;  1A6R A;  1AU3 A;  2OZ2 A;  2FTD A;  4I04 A;  4HWY A;  2BTW B;  3CH2 X;  3K9M A;  3P5X A;  4W5B A;  3RNV A;  3HWN A;  2E01 A;  1F2A A;  1BQI A;  3O65 A;  3PBH A;  2OUL A;  4CDD B;  3IEJ A;  3AI8 A;  5EF4 A;  2G8E A;  1XKG A;  2F7D A;  2P0R A;  3NHE A;  4X6H A;  3KWB X;  3BPF A;  4N8W A;  1EWP A;  4P6G A;  1U9Q X;  3BPM A;  2DC6 A;  5KO3 A;  5JA7 A;  3WXE A;  2CB5 A;  3BWK A;  5CVO B;  1NQC A;  1YK8 A;  2HH5 A;  3M99 A;  1NPZ A;  3H89 A;  3QJ3 A;  4R3D A;  1SNK A;  3BOW A;  2NQI A;  1KXR A;  3IHP A;  3S3R A;  5CHV A;  4YYR A;  2R9N A;  2BDL A;  1QXP A;  2HD5 A;  4K7C A;  2Z84 A;  3LXS A;  1QOL A;  3KKU A;  4BOU A;  3RVX A;  1UKF A;  1PPN A;  4RF1 A;  2AVW A;  1F2C A;  2AUX A;  4OVZ A;  5F02 A;  1NLJ A;  4BOQ A;  1CVZ A;  3BCN A;  1X9Y A;  3E9S A;  4BPV A;  3HHA A;  1PE6 A;  1GEC E;  4YYW A;  4I05 A;  2PBH A;  4D8B A;  2DC7 A;  2IBI A;  2NQG A;  3OIS A;  3IFU A;  4BS6 A;  4A5U A;  2BU3 A;  2E03 A;  4FJC A;  1KHP A;  5CHT A;  2DOS A;  2O6X A;  3N3K A;  1MHW A;  5PAD A;  2WBF X;  3BY4 A;  3IMA A;  2OP3 A;  1AU0 A;  2F1G A;  2HXZ A;  1EWO A;  3WXG A;  2DCD A;  4YVA A;  1ITO A;  2YJ9 A;  4PP1 A;  2IPP B;  3BB7 A;  5EGW A;  2GHU A;  3WXF A;  2AIM A;  2DZZ A;  4ZTB A;  1ICF A;  1CB5 A;  2JTC A;  1SP4 B;  4G54 A;  1S4V A;  2AU1 A;  3H8C A;  4IP3 A;  2R9C A;  1KFU L;  1PVJ A;  1YT7 A;  4QBB A;  2ATO A;  2E02 A;  3I06 A;  3K8U A;  2JRI A;  1ME3 A;  3GCB A;  3KSE A;  1YVB A;  4Q8H A;  1PXV A;  4WUR A;  4DMX A;  1AYU A;  2B1M A;  1NB5 A;  1QMY A;  2PNS A;  2XU5 A;  1U9W A;  2DCB A;  2UZJ A;  4W5C A;  1U9X A;  4OEM A;  1DF0 A;  4BQV A;  4QRX A;  3DF0 A;  1VSN A;  2R9O A;  3MHS A;  2E00 A;  1PBH A;  4Q8G A;  2DC9 A; 
#chains in the Genus database with same CATH homology
 2NQA A;  1PPD A;  3HHI A;  1CTE A;  3IUT A;  1MIR A;  1MEG A;  1Q6K A;  3P5V A;  3HD3 A;  2PAD A;  1TLO A;  2GFO A;  3IV2 A;  1MEM A;  3KFQ A;  2ACT A;  3N4C A;  2AUZ A;  2R6N A;  1VJV A;  2DZY A;  2G7Y A;  4P6E A;  3PNR A;  3U8E A;  3LFY A;  1Y4H A;  3MOR A;  5A24 A;  3KX1 A;  3BC3 A;  3D9W A;  3TNX A;  1CJL A;  3H7D A;  2VFB A;  3H8B A;  2PRE A;  2R9M A;  3K24 A;  1EWM A;  2AYN A;  1ME4 A;  3PW3 A;  1STF E;  5JH3 A;  3KWZ A;  4MZO A;  1PPP A;  4BGF A;  2FQ9 A;  4QRV A;  8PCH A;  4KLB A;  1U5I A;  4W4U A;  1K3B B;  4XR7 A;  4QRG A;  3ERV A;  4BSQ A;  1EF7 A;  4DMY A;  2FRA A;  2R9F A;  3OVZ A;  4PP2 E;  1GX3 A;  2G6D A;  2JQG R;  3V6C A;  4RY2 A;  4N4Z A;  4YYU A;  1NB3 A;  1BGO A;  1F29 A;  3LTW A;  3CBJ A;  4PAD A;  3C9E A;  1DEU A;  2DCA A;  1AU4 A;  4CDC B;  1CQD A;  5CVM A;  2YJ8 A;  1YAL A;  1NL6 A;  2FRQ A;  6PAD A;  3S3Q A;  1CPJ A;  1JQP A;  1AYV A;  3IOQ A;  4GUZ A;  2P86 A;  1CS8 A;  1AYW A;  1MDW A;  4N79 A;  1M6D A;  2VHF A;  1KFX L;  2XU3 A;  2XU4 A;  1GLO A;  1YK7 A;  2B1N A;  2P7U A;  2CIO A;  4YYQ A;  1GMY A;  4PI3 A;  1MS6 A;  2DC8 A;  4NV7 A;  3OF8 A;  2DJF B;  5FPW A;  1IWD A;  1O0E A;  4I07 A;  2FO5 A;  5J94 A;  4WA6 A;  5K16 A;  2AS8 A;  2BSZ A;  3E1Z B;  1PAD A;  4C5P A;  4ZUX U;  1FH0 A;  4B55 A;  3F75 A;  2JQF R;  3USV A;  3RVW A;  1PCI A;  4NV8 A;  2Y5B A;  3QT4 A;  1PPO A;  2FUD A;  4FK5 A;  1Y08 A;  1AIM A;  3MHH A;  2DCC A;  1HUC B;  1KHQ A;  3F5V A;  1BY8 A;  1AEC A;  1ATK A;  3CBK A;  1ZCM A;  2FT2 A;  1CSB B;  2DJG B;  4XUI A;  4CDF B;  3N3G A;  2AYO A;  3I3T A;  3QSD A;  2FYE A;  4OEL A;  2BDZ A;  3P5U A;  1EWL A;  3D6S A;  9PAP A;  4X6I A;  4BS5 A;  2G8J A;  2YJB A;  3O0U A;  4QH6 A;  1BP4 A;  2ARY A;  1THE A;  3H6S A;  3KW9 A;  3V6E A;  4AXL A;  1ZIV A;  4AXM A;  2VHS A;  3OVX A;  4CZW A;  1W6F A;  3ZUA A;  3OF9 A;  2HHN A;  3B79 A;  1AU2 A;  3CH3 X;  2Y6E A;  1PIP A;  3PDF A;  3P5W A;  5CVN B;  3O1G A;  1QDQ A;  4YYS A;  2NQD B;  4YV8 A;  4X6J A;  1U9V A;  1POP A;  7PCK A;  2H7J A;  4MSX A;  4MZS A;  1TL9 A;  3RVV A;  2YJC A;  4CDE B;  2C0Y A;  1GCB A;  2XU1 A;  1E2T A;  1CV8 A;  1F2B A;  2YJ2 A;  3MTN A;  4FIP A;  1TU6 A;  4YYV A;  1A6R A;  1AU3 A;  2OZ2 A;  2FTD A;  4I04 A;  4HWY A;  3CH2 X;  3K9M A;  3P5X A;  4W5B A;  3HWN A;  2E01 A;  1F2A A;  1BQI A;  3PBH A;  2OUL A;  4CDD B;  3IEJ A;  3AI8 A;  1W5R A;  1W4T A;  5EF4 A;  2G8E A;  1XKG A;  2F7D A;  2P0R A;  3NHE A;  2VFC A;  4X6H A;  3KWB X;  3BPF A;  4N8W A;  1EWP A;  4P6G A;  1U9Q X;  3BPM A;  2DC6 A;  5JA7 A;  3WXE A;  2CB5 A;  3BWK A;  5CVO B;  1NQC A;  1YK8 A;  2HH5 A;  3M99 A;  1NPZ A;  3H89 A;  3QJ3 A;  1SNK A;  3BOW A;  2NQI A;  1KXR A;  3IHP A;  3S3R A;  5CHV A;  4YYR A;  2R9N A;  2BDL A;  1QXP A;  2HD5 A;  4K7C A;  3LXS A;  1QOL A;  3KKU A;  3RVX A;  1PPN A;  2AVW A;  1F2C A;  2AUX A;  5F02 A;  1NLJ A;  1CVZ A;  3BCN A;  1X9Y A;  4BPV A;  3HHA A;  1PE6 A;  1GEC E;  4YYW A;  4I05 A;  2PBH A;  2DC7 A;  2IBI A;  2NQG A;  3OIS A;  4BS6 A;  2E03 A;  4FJC A;  1KHP A;  5CHT A;  2O6X A;  3N3K A;  1MHW A;  5PAD A;  2WBF X;  3IMA A;  2OP3 A;  1AU0 A;  2F1G A;  2HXZ A;  1EWO A;  3WXG A;  2DCD A;  4YVA A;  1ITO A;  2YJ9 A;  4PP1 A;  2IPP B;  5EGW A;  2GHU A;  3WXF A;  2AIM A;  2DZZ A;  1ICF A;  1CB5 A;  1SP4 B;  4G54 A;  1S4V A;  2AU1 A;  3H8C A;  2R9C A;  1KFU L;  1YT7 A;  4QBB A;  2ATO A;  2E02 A;  3I06 A;  3K8U A;  1ME3 A;  3GCB A;  3KSE A;  1YVB A;  4Q8H A;  1PXV A;  4DMX A;  1AYU A;  2B1M A;  1NB5 A;  1QMY A;  2PNS A;  2XU5 A;  1U9W A;  2DCB A;  4W5C A;  1U9X A;  4OEM A;  1DF0 A;  4BQV A;  4QRX A;  3DF0 A;  1VSN A;  2R9O A;  3MHS A;  2E00 A;  1PBH A;  4Q8G A;  2DC9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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