1AYVA

Crystal structure of cysteine protease human cathepsin k in complex with a covalent thiazolhydrazide inhibitor
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Design of potent and selective human cathepsin K inhibitors that span the active site.
pubmed doi rcsb
molecule keywords CATHEPSIN K
total genus 61
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 1997-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1ayvA00
1YVBA 4N4ZA 4W5BA 2VHFA 3D6SA 1FH0A 1QXPA 1F29A 1ICFA 1U9VA 1GLOA 4HWYA 2OZ2A 3OVZA 3S3RA 2DJGB 1AU3A 1NL6A 4X6HA 2NQAA 5CHVA 3B79A 2XU4A 4X6IA 3HHAA 1PCIA 4CDCB 2AUZA 2R6NA 2JQGR 3NHEA 5EGWA 2ATOA 1TL9A 1VSNA 1PPOA 1NQCA 3MHHA 1MIRA 2NQIA 5JH3A 1MDWA 1MS6A 5F02A 1BY8A 1TLOA 1PPDA 3RVVA 1U9WA 4MSXA 3IMAA 2R9FA 2YJBA 4FJCA 3QJ3A 1EWPA 4CDDB 4PI3A 3USVA 2DCBA 5CVMA 2NQGA 1F2CA 2HXZA 3O1GA 1ATKA 4P6GA 3CBKA 3N3GA 1AU4A 4BPVA 2R9CA 2IPPB 3K9MA 1AYVA 4I05A 3H8BA 4Q8GA 1NLJA 1JQPA 2FQ9A 1XKGA 1ITOA 3GCBA 2P7UA 1X9YA 8PCHA 1F2AA 3PBHA 1POPA 3CBJA 1KXRA 2CB5A 4PP2E 1CB5A 2B1MA 2R9NA 4YYWA 2VHSA 3IEJA 2P0RA 2HHNA 3KWZA 3U8EA 1AIMA 2AVWA 1O0EA 4OELA 3TNXA 3BC3A 3AI8A 3PDFA 3HD3A 5CVNB 1TU6A 3BOWA 2P86A 2GHUA 3WXEA 1PE6A 4AXLA 3H6SA 3CH2X 3V6EA 3KX1A 1Y4HA 3IUTA 5JA7A 2XU1A 3IOQA 1AU2A 3OVXA 2AYNA 1CVZA 3MORA 5K16A 1MEGA 2PREA 1THEA 2DC6A 3H8CA 4YYSA 1YK8A 2YJ8A 2XU3A 4YYUA 2AIMA 1QOLA 4YYRA 1GCBA 3O0UA 2IBIA 1PPPA 3OF9A 3KSEA 3ZUAA 4MZOA 4AXMA 3WXFA 4QRGA 3C9EA 1MEMA 2YJ2A 3P5UA 4KLBA 1BP4A 1K3BB 1MHWA 1F2BA 3CH3X 2FT2A 2B1NA 4OEMA 2CIOA 3KKUA 3RVXA 4QRVA 2DC9A 2YJ9A 3LFYA 3QSDA 5CVOB 4XR7A 4N79A 3QT4A 3S3QA 4N8WA 2FYEA 5PADA 1EWLA 2BDZA 1M6DA 2NQDB 2DJFB 2FRAA 2BDLA 3PW3A 1YALA 3P5WA 1KFUL 4P6EA 2ARYA 1BGOA 2FO5A 1A6RA 3RVWA 3BPMA 3P5XA 1CSBB 3I3TA 1CJLA 4I07A 2ACTA 5EF4A 1KHQA 1BQIA 2DCDA 2PNSA 3K24A 4FIPA 2FUDA 2AUXA 3M99A 4G54A 3PNRA 1QMYA 5FPWA 2AYOA 1U5IA 4BSQA 4PADA 4CDEB 1CV8A 1DF0A 3MTNA 2E03A 1HUCB 4PP1A 1Y08A 3OF8A 1ME3A 1CTEA 1GECE 4RY2A 2YJCA 1CQDA 4BS5A 3IV2A 1U9QX 4YV8A 1PXVA 4I04A 1CS8A 2R9OA 5A24A 1YK7A 1QDQA 2DCAA 4YVAA 1PIPA 4YYQA 6PADA 2O6XA 1KHPA 5J94A 2G6DA 3BPFA 1GMYA 2G8EA 2G7YA 4K7CA 2XU5A 3KFQA 2DCCA 2DC8A 2E01A 4DMXA 2AS8A 1KFXL 2Y6EA 4W5CA 1YT7A 1AYWA 3OISA 1ME4A 1NPZA 2FRQA 4CDFB 1PPNA 1EF7A 2Y5BA 1STFE 2E00A 3H7DA 1ZIVA 3HWNA 4YYVA 2AU1A 1CPJA 3I06A 1EWOA 2PADA 3HHIA 3F5VA 2WBFX 3DF0A 5CHTA 2OULA 2DZYA 4QH6A 4QBBA 4Q8HA 3P5VA 2DZZA 3BCNA 2F1GA 1S4VA 4XUIA 4QRXA 1DEUA 3KWBX 3MHSA 1AECA 4BS6A 3ERVA 2HD5A 1PBHA 3WXGA 4WA6A 3KW9A 2C0YA 2DC7A 1VJVA 4DMYA 2OP3A 4W4UA 4X6JA 1SNKA 3BWKA 4BQVA 3IHPA 1SP4B 3V6CA 1U9XA 4ZUXU 3E1ZB 3LXSA 1ZCMA 1IWDA 3N3KA 1PADA 4FK5A 4MZSA 2JQFR 3F75A 1EWMA 2PBHA 2GFOA 2E02A 1NB3A 3N4CA 3H89A 2H7JA 9PAPA 3K8UA 4CZWA 1Q6KA 2FTDA 7PCKA 1AYUA 2R9MA 1AU0A 2G8JA 1NB5A 2HH5A 2F7DA
chains in the Genus database with same CATH superfamily
1YVBA 2JTCA 4N4ZA 4W5BA 2VHFA 3D6SA 1FH0A 1QXPA 1F29A 1ICFA 1U9VA 1GLOA 4HWYA 2OZ2A 3OVZA 3S3RA 2DJGB 1AU3A 3TRKA 1NL6A 4X6HA 2NQAA 5CHVA 3B79A 2XU4A 4X6IA 3HHAA 1PCIA 4CDCB 3W30A 2AUZA 3PHUA 2R6NA 2JQGR 3NHEA 5EGWA 2ATOA 1TL9A 1VSNA 1PPOA 1NQCA 3OQCA 3MHHA 1MIRA 2NQIA 5JH3A 4RKXA 1MDWA 1MS6A 5F02A 1BY8A 1TLOA 1PPDA 3RVVA 1U9WA 4MSXA 3IMAA 2FE8A 2R9FA 2YJBA 4FJCA 3QJ3A 3PHXA 1EWPA 4CDDB 4PI3A 3USVA 2DCBA 4OVZA 5CVMA 2NQGA 4MM3B 1F2CA 2HXZA 3O1GA 1ATKA 4P6GA 3CBKA 3N3GA 1AU4A 4BPVA 2R9CA 4IUMA 4HXDB 2IPPB 3K9MA 1AYVA 4I05A 3H8BA 4Q8GA 4XZXA 1NLJA 1JQPA 2FQ9A 1XKGA 1ITOA 3GCBA 2BTWA 2P7UA 1X9YA 8PCHA 1F2AA 3PBHA 1POPA 3CBJA 1KXRA 2CB5A 4M0WA 4PP2E 1CB5A 2B1MA 2R9NA 4YYWA 2VHSA 3IEJA 2P0RA 3C0RA 2HHNA 3KWZA 3U8EA 1AIMA 2AVWA 1O0EA 4OELA 3TNXA 3BC3A 3AI8A 3PDFA 3HD3A 5CVNB 1TU6A 3BOWA 2P86A 2GHUA 3WXEA 1PE6A 4AXLA 3H6SA 3TMPA 3CH2X 4R3DA 3KX1A 3V6EA 1Y4HA 3IUTA 5JA7A 2XU1A 3IOQA 1AU2A 3OVXA 3PRPA 2AYNA 1CVZA 2BU3A 3MORA 5K16A 1MEGA 2PREA 1THEA 2DC6A 3H8CA 4YYSA 1YK8A 2YJ8A 2XU3A 4YYUA 2AIMA 4GUAA 1QOLA 4ZTBA 3MJ5A 4YYRA 1GCBA 3O0UA 2IBIA 1PPPA 3OF9A 3KSEA 3ZUAA 4MZOA 4AXMA 3O65A 3WXFA 4QRGA 3C9EA 1MEMA 4OVZB 2YJ2A 3P5UA 4KLBA 1BP4A 1K3BB 1MHWA 1F2BA 4P16A 3CH3X 2FT2A 4BOQA 2B1NA 4OEMA 3MTVA 2CIOA 3KKUA 3RVXA 4QRVA 2DC9A 4MI7A 2YJ9A 3LFYA 3QSDA 5CVOB 4XR7A 1PVJA 3MP2A 2BTWB 4N79A 3QT4A 3S3QA 4D8BA 4N8WA 1YZBA 2FYEA 5PADA 4D8EA 1EWLA 2BDZA 1M6DA 2NQDB 2DJFB 2FRAA 2BDLA 3PW3A 1YALA 3P5WA 1KFUL 4P6EA 2ARYA 4BOPA 1BGOA 2FO5A 2AGAA 3W31A 1A6RA 3RVWA 3BPMA 3P5XA 2HWKA 1CSBB 3BB7A 3I3TA 1CJLA 4I07A 2ACTA 2Z84A 4BOZA 5EF4A 1KHQA 1BQIA 2DCDA 2PNSA 3K24A 4FIPA 2FUDA 2AUXA 3M99A 4G54A 3PNRA 1QMYA 5FPWA 2AYOA 1U5IA 4BSQA 4PADA 4CDEB 1CV8A 1DF0A 4D8IA 3MTNA 2E03A 1HUCB 4PP1A 1Y08A 3OF8A 1ME3A 4REZA 1CTEA 1GECE 4RY2A 2YJCA 1CQDA 4BS5A 3IV2A 1U9QX 4YV8A 3E9SA 1PXVA 4I04A 1CS8A 2R9OA 5A24A 1YK7A 1QDQA 2DCAA 4YVAA 1PIPA 2DOSA 4YYQA 6PADA 2O6XA 1KHPA 5EZSA 5J94A 2G6DA 3BPFA 1GMYA 2G8EA 2G7YA 1DKIA 4OW0A 4K7CA 3B21A 2XU5A 3KFQA 2DCCA 2DC8A 4RNAA 3PT2A 2E01A 4DMXA 2AS8A 1KFXL 2Y6EA 4W5CA 1YT7A 1AYWA 3OISA 1ME4A 4BOUA 2UZJA 1UKFA 1NPZA 5EZQA 2FRQA 4CDFB 1PPNA 2JRIA 1EF7A 2Y5BA 1STFE 2E00A 3H7DA 1ZIVA 3HWNA 4YYVA 2AU1A 1CPJA 3I06A 1EWOA 2PADA 3HHIA 3F5VA 2WBFX 3DF0A 5CHTA 2OULA 2DZYA 3PHWA 4QH6A 4QBBA 4PT5A 3P5VA 4Q8HA 2DZZA 3BCNA 2F1GA 1S4VA 4XUIA 4QRXA 2J7QC 4WURA 4IP3A 2J7QA 1DEUA 3KWBX 3MHSA 1AECA 4BS6A 3ERVA 3BY4A 4A5UA 2HD5A 1PBHA 3WXGA 3RNVA 4WA6A 3KW9A 2C0YA 2DC7A 3IFUA 1VJVA 4DMYA 2OP3A 4RF1A 4W4UA 3PRMA 4X6JA 1SNKA 3BWKA 4BQVA 5E6JA 4RF0A 3IHPA 1SP4B 3V6CA 1U9XA 4ZUXU 3E1ZB 3LXSA 1ZCMA 1IWDA 3N3KA 1PADA 4FK5A 4MZSA 2JQFR 3F75A 1EWMA 2PBHA 2GFOA 5KO3A 2E02A 4BOSA 1NB3A 3N4CA 3H89A 2H7JA 9PAPA 3K8UA 3ZNHA 3PSEA 4CZWA 5JZEA 1Q6KA 2FTDA 3BBAA 7PCKA 1AYUA 2R9MA 1AU0A 2G8JA 1NB5A 2HH5A 2F7DA
chains in the Genus database with same CATH topology
1YVBA 4N4ZA 4W5BA 2VHFA 3D6SA 1FH0A 1QXPA 1F29A 1ICFA 1U9VA 1GLOA 4HWYA 2OZ2A 3OVZA 3S3RA 2DJGB 1AU3A 4NV8A 1NL6A 4X6HA 2NQAA 5CHVA 3B79A 2XU4A 4X6IA 3HHAA 1PCIA 4CDCB 2AUZA 2R6NA 2JQGR 3NHEA 5EGWA 2ATOA 1TL9A 1VSNA 1PPOA 1NQCA 3MHHA 1MIRA 2NQIA 5JH3A 1MDWA 1MS6A 5F02A 1BY8A 1TLOA 1PPDA 3RVVA 1U9WA 4MSXA 3IMAA 3D9WA 2R9FA 2YJBA 4FJCA 3QJ3A 4B55A 1EWPA 4CDDB 4PI3A 3USVA 2DCBA 5CVMA 2NQGA 1F2CA 2HXZA 1W5RA 3O1GA 1ATKA 4P6GA 3CBKA 3N3GA 1AU4A 4BPVA 2R9CA 2IPPB 3K9MA 1AYVA 4I05A 3H8BA 4Q8GA 1NLJA 1JQPA 2FQ9A 1XKGA 1ITOA 3GCBA 2P7UA 1X9YA 8PCHA 1F2AA 3PBHA 1POPA 3CBJA 1KXRA 2CB5A 4PP2E 1CB5A 2B1MA 2R9NA 4YYWA 2VHSA 3IEJA 2P0RA 2HHNA 3KWZA 3U8EA 1AIMA 2AVWA 1O0EA 4OELA 3TNXA 3BC3A 3AI8A 3PDFA 3HD3A 1GX3A 1TU6A 5CVNB 3BOWA 2P86A 2GHUA 3WXEA 1PE6A 4AXLA 3H6SA 3CH2X 3V6EA 3KX1A 1Y4HA 3IUTA 5JA7A 2XU1A 3IOQA 1AU2A 3OVXA 2AYNA 1CVZA 4NV7A 3MORA 5K16A 1MEGA 2PREA 1THEA 2DC6A 3H8CA 4YYSA 1YK8A 2YJ8A 2XU3A 4YYUA 2AIMA 1QOLA 4YYRA 1GCBA 3O0UA 2IBIA 1PPPA 3OF9A 3KSEA 3ZUAA 4MZOA 4AXMA 3WXFA 4QRGA 3C9EA 1MEMA 2YJ2A 3P5UA 4KLBA 1BP4A 1K3BB 1MHWA 1F2BA 3CH3X 2FT2A 2B1NA 4OEMA 2CIOA 3KKUA 4C5PA 3RVXA 4QRVA 2DC9A 2YJ9A 3LFYA 3QSDA 5CVOB 4XR7A 4N79A 3QT4A 4GUZA 3S3QA 4N8WA 2FYEA 5PADA 1EWLA 2BDZA 1M6DA 1W6FA 2NQDB 2DJFB 2FRAA 2BDLA 3PW3A 1YALA 3P5WA 1KFUL 4P6EA 2ARYA 1BGOA 2FO5A 1A6RA 3RVWA 3BPMA 3P5XA 1CSBB 3I3TA 1CJLA 4I07A 2ACTA 5EF4A 1KHQA 2VFBA 1BQIA 2DCDA 2PNSA 3K24A 4FIPA 2FUDA 2AUXA 3M99A 4G54A 3PNRA 1QMYA 5FPWA 2AYOA 1U5IA 4BSQA 4PADA 4CDEB 1CV8A 1DF0A 3MTNA 2E03A 1HUCB 4PP1A 1Y08A 3OF8A 1E2TA 1ME3A 1CTEA 1GECE 4RY2A 2YJCA 1CQDA 4BS5A 2BSZA 3IV2A 1U9QX 4YV8A 1PXVA 4I04A 1CS8A 2R9OA 5A24A 1YK7A 1QDQA 2DCAA 3LTWA 4YVAA 1PIPA 4YYQA 6PADA 2O6XA 1KHPA 5J94A 2G6DA 3BPFA 1GMYA 2G8EA 2G7YA 4K7CA 2XU5A 3KFQA 2DCCA 2DC8A 2E01A 4DMXA 2AS8A 1KFXL 1W4TA 2Y6EA 4W5CA 1YT7A 1AYWA 3OISA 1ME4A 1NPZA 2FRQA 4CDFB 1PPNA 1EF7A 2Y5BA 1STFE 2E00A 3H7DA 1ZIVA 3HWNA 4YYVA 2AU1A 1CPJA 3I06A 1EWOA 2PADA 3HHIA 3F5VA 2WBFX 3DF0A 5CHTA 2OULA 2DZYA 4QH6A 4QBBA 4Q8HA 3P5VA 2DZZA 3BCNA 2F1GA 1S4VA 4XUIA 4QRXA 4BGFA 1DEUA 3KWBX 3MHSA 1AECA 4BS6A 3ERVA 2HD5A 1PBHA 3WXGA 4WA6A 3KW9A 2C0YA 2DC7A 1VJVA 4DMYA 2OP3A 4W4UA 4X6JA 1SNKA 3BWKA 4BQVA 2VFCA 3IHPA 1SP4B 3V6CA 1U9XA 4ZUXU 3E1ZB 3LXSA 1ZCMA 1IWDA 3N3KA 1PADA 4FK5A 4MZSA 2JQFR 3F75A 1EWMA 2PBHA 2GFOA 2E02A 1NB3A 3N4CA 3H89A 2H7JA 9PAPA 3K8UA 4CZWA 1Q6KA 2FTDA 7PCKA 1AYUA 2R9MA 1AU0A 2G8JA 1NB5A 2HH5A 2F7DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YVB A;  4N4Z A;  4W5B A;  2VHF A;  3D6S A;  1FH0 A;  1QXP A;  1F29 A;  1ICF A;  1U9V A;  1GLO A;  4HWY A;  2OZ2 A;  3OVZ A;  3S3R A;  2DJG B;  1AU3 A;  1NL6 A;  4X6H A;  2NQA A;  5CHV A;  3B79 A;  2XU4 A;  4X6I A;  3HHA A;  1PCI A;  4CDC B;  2AUZ A;  2R6N A;  2JQG R;  3NHE A;  5EGW A;  2ATO A;  1TL9 A;  1VSN A;  1PPO A;  1NQC A;  3MHH A;  1MIR A;  2NQI A;  5JH3 A;  1MDW A;  1MS6 A;  5F02 A;  1BY8 A;  1TLO A;  1PPD A;  3RVV A;  1U9W A;  4MSX A;  3IMA A;  2R9F A;  2YJB A;  4FJC A;  3QJ3 A;  1EWP A;  4CDD B;  4PI3 A;  3USV A;  2DCB A;  5CVM A;  2NQG A;  1F2C A;  2HXZ A;  3O1G A;  1ATK A;  4P6G A;  3CBK A;  3N3G A;  1AU4 A;  4BPV A;  2R9C A;  2IPP B;  3K9M A;  1AYV A;  4I05 A;  3H8B A;  4Q8G A;  1NLJ A;  1JQP A;  2FQ9 A;  1XKG A;  1ITO A;  3GCB A;  2P7U A;  1X9Y A;  8PCH A;  1F2A A;  3PBH A;  1POP A;  3CBJ A;  1KXR A;  2CB5 A;  4PP2 E;  1CB5 A;  2B1M A;  2R9N A;  4YYW A;  2VHS A;  3IEJ A;  2P0R A;  2HHN A;  3KWZ A;  3U8E A;  1AIM A;  2AVW A;  1O0E A;  4OEL A;  3TNX A;  3BC3 A;  3AI8 A;  3PDF A;  3HD3 A;  5CVN B;  1TU6 A;  3BOW A;  2P86 A;  2GHU A;  3WXE A;  1PE6 A;  4AXL A;  3H6S A;  3CH2 X;  3V6E A;  3KX1 A;  1Y4H A;  3IUT A;  5JA7 A;  2XU1 A;  3IOQ A;  1AU2 A;  3OVX A;  2AYN A;  1CVZ A;  3MOR A;  5K16 A;  1MEG A;  2PRE A;  1THE A;  2DC6 A;  3H8C A;  4YYS A;  1YK8 A;  2YJ8 A;  2XU3 A;  4YYU A;  2AIM A;  1QOL A;  4YYR A;  1GCB A;  3O0U A;  2IBI A;  1PPP A;  3OF9 A;  3KSE A;  3ZUA A;  4MZO A;  4AXM A;  3WXF A;  4QRG A;  3C9E A;  1MEM A;  2YJ2 A;  3P5U A;  4KLB A;  1BP4 A;  1K3B B;  1MHW A;  1F2B A;  3CH3 X;  2FT2 A;  2B1N A;  4OEM A;  2CIO A;  3KKU A;  3RVX A;  4QRV A;  2DC9 A;  2YJ9 A;  3LFY A;  3QSD A;  5CVO B;  4XR7 A;  4N79 A;  3QT4 A;  3S3Q A;  4N8W A;  2FYE A;  5PAD A;  1EWL A;  2BDZ A;  1M6D A;  2NQD B;  2DJF B;  2FRA A;  2BDL A;  3PW3 A;  1YAL A;  3P5W A;  1KFU L;  4P6E A;  2ARY A;  1BGO A;  2FO5 A;  1A6R A;  3RVW A;  3BPM A;  3P5X A;  1CSB B;  3I3T A;  1CJL A;  4I07 A;  2ACT A;  5EF4 A;  1KHQ A;  1BQI A;  2DCD A;  2PNS A;  3K24 A;  4FIP A;  2FUD A;  2AUX A;  3M99 A;  4G54 A;  3PNR A;  1QMY A;  5FPW A;  2AYO A;  1U5I A;  4BSQ A;  4PAD A;  4CDE B;  1CV8 A;  1DF0 A;  3MTN A;  2E03 A;  1HUC B;  4PP1 A;  1Y08 A;  3OF8 A;  1ME3 A;  1CTE A;  1GEC E;  4RY2 A;  2YJC A;  1CQD A;  4BS5 A;  3IV2 A;  1U9Q X;  4YV8 A;  1PXV A;  4I04 A;  1CS8 A;  2R9O A;  5A24 A;  1YK7 A;  1QDQ A;  2DCA A;  4YVA A;  1PIP A;  4YYQ A;  6PAD A;  2O6X A;  1KHP A;  5J94 A;  2G6D A;  3BPF A;  1GMY A;  2G8E A;  2G7Y A;  4K7C A;  2XU5 A;  3KFQ A;  2DCC A;  2DC8 A;  2E01 A;  4DMX A;  2AS8 A;  1KFX L;  2Y6E A;  4W5C A;  1YT7 A;  1AYW A;  3OIS A;  1ME4 A;  1NPZ A;  2FRQ A;  4CDF B;  1PPN A;  1EF7 A;  2Y5B A;  1STF E;  2E00 A;  3H7D A;  1ZIV A;  3HWN A;  4YYV A;  2AU1 A;  1CPJ A;  3I06 A;  1EWO A;  2PAD A;  3HHI A;  3F5V A;  2WBF X;  3DF0 A;  5CHT A;  2OUL A;  2DZY A;  4QH6 A;  4QBB A;  4Q8H A;  3P5V A;  2DZZ A;  3BCN A;  2F1G A;  1S4V A;  4XUI A;  4QRX A;  1DEU A;  3KWB X;  3MHS A;  1AEC A;  4BS6 A;  3ERV A;  2HD5 A;  1PBH A;  3WXG A;  4WA6 A;  3KW9 A;  2C0Y A;  2DC7 A;  1VJV A;  4DMY A;  2OP3 A;  4W4U A;  4X6J A;  1SNK A;  3BWK A;  4BQV A;  3IHP A;  1SP4 B;  3V6C A;  1U9X A;  4ZUX U;  3E1Z B;  3LXS A;  1ZCM A;  1IWD A;  3N3K A;  1PAD A;  4FK5 A;  4MZS A;  2JQF R;  3F75 A;  1EWM A;  2PBH A;  2GFO A;  2E02 A;  1NB3 A;  3N4C A;  3H89 A;  2H7J A;  9PAP A;  3K8U A;  4CZW A;  1Q6K A;  2FTD A;  7PCK A;  1AYU A;  2R9M A;  1AU0 A;  2G8J A;  1NB5 A;  2HH5 A;  2F7D A; 
#chains in the Genus database with same CATH topology
 1YVB A;  2JTC A;  4N4Z A;  4W5B A;  2VHF A;  3D6S A;  1FH0 A;  1QXP A;  1F29 A;  1ICF A;  1U9V A;  1GLO A;  4HWY A;  2OZ2 A;  3OVZ A;  3S3R A;  2DJG B;  1AU3 A;  3TRK A;  1NL6 A;  4X6H A;  2NQA A;  5CHV A;  3B79 A;  2XU4 A;  4X6I A;  3HHA A;  1PCI A;  4CDC B;  3W30 A;  2AUZ A;  3PHU A;  2R6N A;  2JQG R;  3NHE A;  5EGW A;  2ATO A;  1TL9 A;  1VSN A;  1PPO A;  1NQC A;  3OQC A;  3MHH A;  1MIR A;  2NQI A;  5JH3 A;  4RKX A;  1MDW A;  1MS6 A;  5F02 A;  1BY8 A;  1TLO A;  1PPD A;  3RVV A;  1U9W A;  4MSX A;  3IMA A;  2FE8 A;  2R9F A;  2YJB A;  4FJC A;  3QJ3 A;  3PHX A;  1EWP A;  4CDD B;  4PI3 A;  3USV A;  2DCB A;  4OVZ A;  5CVM A;  2NQG A;  4MM3 B;  1F2C A;  2HXZ A;  3O1G A;  1ATK A;  4P6G A;  3CBK A;  3N3G A;  1AU4 A;  4BPV A;  2R9C A;  4IUM A;  4HXD B;  2IPP B;  3K9M A;  1AYV A;  4I05 A;  3H8B A;  4Q8G A;  4XZX A;  1NLJ A;  1JQP A;  2FQ9 A;  1XKG A;  1ITO A;  3GCB A;  2BTW A;  2P7U A;  1X9Y A;  8PCH A;  1F2A A;  3PBH A;  1POP A;  3CBJ A;  1KXR A;  2CB5 A;  4M0W A;  4PP2 E;  1CB5 A;  2B1M A;  2R9N A;  4YYW A;  2VHS A;  3IEJ A;  2P0R A;  3C0R A;  2HHN A;  3KWZ A;  3U8E A;  1AIM A;  2AVW A;  1O0E A;  4OEL A;  3TNX A;  3BC3 A;  3AI8 A;  3PDF A;  3HD3 A;  5CVN B;  1TU6 A;  3BOW A;  2P86 A;  2GHU A;  3WXE A;  1PE6 A;  4AXL A;  3H6S A;  3TMP A;  3CH2 X;  4R3D A;  3KX1 A;  3V6E A;  1Y4H A;  3IUT A;  5JA7 A;  2XU1 A;  3IOQ A;  1AU2 A;  3OVX A;  3PRP A;  2AYN A;  1CVZ A;  2BU3 A;  3MOR A;  5K16 A;  1MEG A;  2PRE A;  1THE A;  2DC6 A;  3H8C A;  4YYS A;  1YK8 A;  2YJ8 A;  2XU3 A;  4YYU A;  2AIM A;  4GUA A;  1QOL A;  4ZTB A;  3MJ5 A;  4YYR A;  1GCB A;  3O0U A;  2IBI A;  1PPP A;  3OF9 A;  3KSE A;  3ZUA A;  4MZO A;  4AXM A;  3O65 A;  3WXF A;  4QRG A;  3C9E A;  1MEM A;  4OVZ B;  2YJ2 A;  3P5U A;  4KLB A;  1BP4 A;  1K3B B;  1MHW A;  1F2B A;  4P16 A;  3CH3 X;  2FT2 A;  4BOQ A;  2B1N A;  4OEM A;  3MTV A;  2CIO A;  3KKU A;  3RVX A;  4QRV A;  2DC9 A;  4MI7 A;  2YJ9 A;  3LFY A;  3QSD A;  5CVO B;  4XR7 A;  1PVJ A;  3MP2 A;  2BTW B;  4N79 A;  3QT4 A;  3S3Q A;  4D8B A;  4N8W A;  1YZB A;  2FYE A;  5PAD A;  4D8E A;  1EWL A;  2BDZ A;  1M6D A;  2NQD B;  2DJF B;  2FRA A;  2BDL A;  3PW3 A;  1YAL A;  3P5W A;  1KFU L;  4P6E A;  2ARY A;  4BOP A;  1BGO A;  2FO5 A;  2AGA A;  3W31 A;  1A6R A;  3RVW A;  3BPM A;  3P5X A;  2HWK A;  1CSB B;  3BB7 A;  3I3T A;  1CJL A;  4I07 A;  2ACT A;  2Z84 A;  4BOZ A;  5EF4 A;  1KHQ A;  1BQI A;  2DCD A;  2PNS A;  3K24 A;  4FIP A;  2FUD A;  2AUX A;  3M99 A;  4G54 A;  3PNR A;  1QMY A;  5FPW A;  2AYO A;  1U5I A;  4BSQ A;  4PAD A;  4CDE B;  1CV8 A;  1DF0 A;  4D8I A;  3MTN A;  2E03 A;  1HUC B;  4PP1 A;  1Y08 A;  3OF8 A;  1ME3 A;  4REZ A;  1CTE A;  1GEC E;  4RY2 A;  2YJC A;  1CQD A;  4BS5 A;  3IV2 A;  1U9Q X;  4YV8 A;  3E9S A;  1PXV A;  4I04 A;  1CS8 A;  2R9O A;  5A24 A;  1YK7 A;  1QDQ A;  2DCA A;  4YVA A;  1PIP A;  2DOS A;  4YYQ A;  6PAD A;  2O6X A;  1KHP A;  5EZS A;  5J94 A;  2G6D A;  3BPF A;  1GMY A;  2G8E A;  2G7Y A;  1DKI A;  4OW0 A;  4K7C A;  3B21 A;  2XU5 A;  3KFQ A;  2DCC A;  2DC8 A;  4RNA A;  3PT2 A;  2E01 A;  4DMX A;  2AS8 A;  1KFX L;  2Y6E A;  4W5C A;  1YT7 A;  1AYW A;  3OIS A;  1ME4 A;  4BOU A;  2UZJ A;  1UKF A;  1NPZ A;  5EZQ A;  2FRQ A;  4CDF B;  1PPN A;  2JRI A;  1EF7 A;  2Y5B A;  1STF E;  2E00 A;  3H7D A;  1ZIV A;  3HWN A;  4YYV A;  2AU1 A;  1CPJ A;  3I06 A;  1EWO A;  2PAD A;  3HHI A;  3F5V A;  2WBF X;  3DF0 A;  5CHT A;  2OUL A;  2DZY A;  3PHW A;  4QH6 A;  4QBB A;  4PT5 A;  3P5V A;  4Q8H A;  2DZZ A;  3BCN A;  2F1G A;  1S4V A;  4XUI A;  4QRX A;  2J7Q C;  4WUR A;  4IP3 A;  2J7Q A;  1DEU A;  3KWB X;  3MHS A;  1AEC A;  4BS6 A;  3ERV A;  3BY4 A;  4A5U A;  2HD5 A;  1PBH A;  3WXG A;  3RNV A;  4WA6 A;  3KW9 A;  2C0Y A;  2DC7 A;  3IFU A;  1VJV A;  4DMY A;  2OP3 A;  4RF1 A;  4W4U A;  3PRM A;  4X6J A;  1SNK A;  3BWK A;  4BQV A;  5E6J A;  4RF0 A;  3IHP A;  1SP4 B;  3V6C A;  1U9X A;  4ZUX U;  3E1Z B;  3LXS A;  1ZCM A;  1IWD A;  3N3K A;  1PAD A;  4FK5 A;  4MZS A;  2JQF R;  3F75 A;  1EWM A;  2PBH A;  2GFO A;  5KO3 A;  2E02 A;  4BOS A;  1NB3 A;  3N4C A;  3H89 A;  2H7J A;  9PAP A;  3K8U A;  3ZNH A;  3PSE A;  4CZW A;  5JZE A;  1Q6K A;  2FTD A;  3BBA A;  7PCK A;  1AYU A;  2R9M A;  1AU0 A;  2G8J A;  1NB5 A;  2HH5 A;  2F7D A; 
#chains in the Genus database with same CATH homology
 1YVB A;  4N4Z A;  4W5B A;  2VHF A;  3D6S A;  1FH0 A;  1QXP A;  1F29 A;  1ICF A;  1U9V A;  1GLO A;  4HWY A;  2OZ2 A;  3OVZ A;  3S3R A;  2DJG B;  1AU3 A;  4NV8 A;  1NL6 A;  4X6H A;  2NQA A;  5CHV A;  3B79 A;  2XU4 A;  4X6I A;  3HHA A;  1PCI A;  4CDC B;  2AUZ A;  2R6N A;  2JQG R;  3NHE A;  5EGW A;  2ATO A;  1TL9 A;  1VSN A;  1PPO A;  1NQC A;  3MHH A;  1MIR A;  2NQI A;  5JH3 A;  1MDW A;  1MS6 A;  5F02 A;  1BY8 A;  1TLO A;  1PPD A;  3RVV A;  1U9W A;  4MSX A;  3IMA A;  3D9W A;  2R9F A;  2YJB A;  4FJC A;  3QJ3 A;  4B55 A;  1EWP A;  4CDD B;  4PI3 A;  3USV A;  2DCB A;  5CVM A;  2NQG A;  1F2C A;  2HXZ A;  1W5R A;  3O1G A;  1ATK A;  4P6G A;  3CBK A;  3N3G A;  1AU4 A;  4BPV A;  2R9C A;  2IPP B;  3K9M A;  1AYV A;  4I05 A;  3H8B A;  4Q8G A;  1NLJ A;  1JQP A;  2FQ9 A;  1XKG A;  1ITO A;  3GCB A;  2P7U A;  1X9Y A;  8PCH A;  1F2A A;  3PBH A;  1POP A;  3CBJ A;  1KXR A;  2CB5 A;  4PP2 E;  1CB5 A;  2B1M A;  2R9N A;  4YYW A;  2VHS A;  3IEJ A;  2P0R A;  2HHN A;  3KWZ A;  3U8E A;  1AIM A;  2AVW A;  1O0E A;  4OEL A;  3TNX A;  3BC3 A;  3AI8 A;  3PDF A;  3HD3 A;  1GX3 A;  1TU6 A;  5CVN B;  3BOW A;  2P86 A;  2GHU A;  3WXE A;  1PE6 A;  4AXL A;  3H6S A;  3CH2 X;  3V6E A;  3KX1 A;  1Y4H A;  3IUT A;  5JA7 A;  2XU1 A;  3IOQ A;  1AU2 A;  3OVX A;  2AYN A;  1CVZ A;  4NV7 A;  3MOR A;  5K16 A;  1MEG A;  2PRE A;  1THE A;  2DC6 A;  3H8C A;  4YYS A;  1YK8 A;  2YJ8 A;  2XU3 A;  4YYU A;  2AIM A;  1QOL A;  4YYR A;  1GCB A;  3O0U A;  2IBI A;  1PPP A;  3OF9 A;  3KSE A;  3ZUA A;  4MZO A;  4AXM A;  3WXF A;  4QRG A;  3C9E A;  1MEM A;  2YJ2 A;  3P5U A;  4KLB A;  1BP4 A;  1K3B B;  1MHW A;  1F2B A;  3CH3 X;  2FT2 A;  2B1N A;  4OEM A;  2CIO A;  3KKU A;  4C5P A;  3RVX A;  4QRV A;  2DC9 A;  2YJ9 A;  3LFY A;  3QSD A;  5CVO B;  4XR7 A;  4N79 A;  3QT4 A;  4GUZ A;  3S3Q A;  4N8W A;  2FYE A;  5PAD A;  1EWL A;  2BDZ A;  1M6D A;  1W6F A;  2NQD B;  2DJF B;  2FRA A;  2BDL A;  3PW3 A;  1YAL A;  3P5W A;  1KFU L;  4P6E A;  2ARY A;  1BGO A;  2FO5 A;  1A6R A;  3RVW A;  3BPM A;  3P5X A;  1CSB B;  3I3T A;  1CJL A;  4I07 A;  2ACT A;  5EF4 A;  1KHQ A;  2VFB A;  1BQI A;  2DCD A;  2PNS A;  3K24 A;  4FIP A;  2FUD A;  2AUX A;  3M99 A;  4G54 A;  3PNR A;  1QMY A;  5FPW A;  2AYO A;  1U5I A;  4BSQ A;  4PAD A;  4CDE B;  1CV8 A;  1DF0 A;  3MTN A;  2E03 A;  1HUC B;  4PP1 A;  1Y08 A;  3OF8 A;  1E2T A;  1ME3 A;  1CTE A;  1GEC E;  4RY2 A;  2YJC A;  1CQD A;  4BS5 A;  2BSZ A;  3IV2 A;  1U9Q X;  4YV8 A;  1PXV A;  4I04 A;  1CS8 A;  2R9O A;  5A24 A;  1YK7 A;  1QDQ A;  2DCA A;  3LTW A;  4YVA A;  1PIP A;  4YYQ A;  6PAD A;  2O6X A;  1KHP A;  5J94 A;  2G6D A;  3BPF A;  1GMY A;  2G8E A;  2G7Y A;  4K7C A;  2XU5 A;  3KFQ A;  2DCC A;  2DC8 A;  2E01 A;  4DMX A;  2AS8 A;  1KFX L;  1W4T A;  2Y6E A;  4W5C A;  1YT7 A;  1AYW A;  3OIS A;  1ME4 A;  1NPZ A;  2FRQ A;  4CDF B;  1PPN A;  1EF7 A;  2Y5B A;  1STF E;  2E00 A;  3H7D A;  1ZIV A;  3HWN A;  4YYV A;  2AU1 A;  1CPJ A;  3I06 A;  1EWO A;  2PAD A;  3HHI A;  3F5V A;  2WBF X;  3DF0 A;  5CHT A;  2OUL A;  2DZY A;  4QH6 A;  4QBB A;  4Q8H A;  3P5V A;  2DZZ A;  3BCN A;  2F1G A;  1S4V A;  4XUI A;  4QRX A;  4BGF A;  1DEU A;  3KWB X;  3MHS A;  1AEC A;  4BS6 A;  3ERV A;  2HD5 A;  1PBH A;  3WXG A;  4WA6 A;  3KW9 A;  2C0Y A;  2DC7 A;  1VJV A;  4DMY A;  2OP3 A;  4W4U A;  4X6J A;  1SNK A;  3BWK A;  4BQV A;  2VFC A;  3IHP A;  1SP4 B;  3V6C A;  1U9X A;  4ZUX U;  3E1Z B;  3LXS A;  1ZCM A;  1IWD A;  3N3K A;  1PAD A;  4FK5 A;  4MZS A;  2JQF R;  3F75 A;  1EWM A;  2PBH A;  2GFO A;  2E02 A;  1NB3 A;  3N4C A;  3H89 A;  2H7J A;  9PAP A;  3K8U A;  4CZW A;  1Q6K A;  2FTD A;  7PCK A;  1AYU A;  2R9M A;  1AU0 A;  2G8J A;  1NB5 A;  2HH5 A;  2F7D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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