1AYWA

Crystal structure of cysteine protease human cathepsin k in complex with a covalent benzyloxybenzoylcarbohydrazide inhibitor
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Design of potent and selective human cathepsin K inhibitors that span the active site.
pubmed doi rcsb
molecule keywords CATHEPSIN K
total genus 57
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 1997-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1aywA00
1YALA 1KXRA 4CZWA 3BC3A 3K24A 3OF8A 3H89A 3K8UA 3HD3A 1CS8A 3H8BA 3OF9A 1YK8A 4CDEB 3IEJA 1BP4A 4ZUXU 9PAPA 2VHFA 2CB5A 2G8EA 5EGWA 4CDDB 1ZCMA 4MZOA 1EWLA 2YJ9A 3IMAA 1AU3A 1CV8A 3RVVA 3RVWA 2R9OA 3H7DA 1Y08A 1PPNA 4RY2A 1ICFA 1ME3A 4BQVA 3K9MA 2HH5A 2AUZA 2VHSA 2NQIA 1IWDA 2R9NA 4I07A 2E03A 1NB3A 2DC6A 3P5VA 4CDFB 4Q8HA 3E1ZB 2YJ2A 5FPWA 2DJGB 2R6NA 3QJ3A 1HUCB 5J94A 8PCHA 2R9MA 2B1MA 1U9QX 4W5BA 2AU1A 1PXVA 3V6EA 3P5XA 4N8WA 2DCAA 5F02A 4BS6A 4YYQA 3LFYA 1NQCA 4MSXA 4OELA 2G6DA 2E00A 3MTNA 4FIPA 3MHSA 4K7CA 1F2BA 1THEA 2AIMA 4YYVA 3O1GA 4YYWA 2NQAA 4G54A 1BGOA 3BPFA 1CJLA 2ATOA 4FK5A 4PP2E 2YJ8A 3KWBX 1S4VA 2AVWA 3D6SA 5EF4A 3KFQA 1MIRA 2NQDB 1ZIVA 1Y4HA 1A6RA 3N3GA 4BS5A 3KWZA 2H7JA 3PW3A 1ITOA 1EF7A 5JA7A 3BCNA 2DCBA 1F29A 5CVMA 2P0RA 4FJCA 2F1GA 1ATKA 1TL9A 2AYOA 3P5WA 3KSEA 2GHUA 4QH6A 3H6SA 1U5IA 3ZUAA 2NQGA 1CVZA 1NL6A 2F7DA 1XKGA 1SP4B 1MEGA 3OVXA 1AYVA 1GECE 4PI3A 3F75A 2BDZA 3P5UA 3MORA 2JQFR 2G8JA 3F5VA 2FUDA 4P6EA 3MHHA 4BSQA 1AIMA 3U8EA 3DF0A 4DMYA 2FTDA 3QT4A 1CTEA 2FO5A 1YVBA 4YYRA 1MHWA 3IOQA 1TLOA 7PCKA 3HHIA 1BY8A 4YV8A 2G7YA 2E02A 2IPPB 2XU1A 3CBJA 2OULA 3OVZA 3TNXA 1U9XA 3O0UA 3NHEA 2WBFX 2HXZA 3WXGA 1DF0A 1AU4A 1NPZA 3WXEA 4I05A 3GCBA 1PE6A 2DC8A 2OP3A 1U9VA 3I3TA 2BDLA 1CB5A 3C9EA 2PNSA 1PPDA 1NB5A 1YK7A 4MZSA 2ACTA 5CHVA 2XU5A 1EWPA 1AYWA 1PPPA 1NLJA 1VSNA 2DC7A 3V6CA 2R9CA 1GCBA 1MEMA 2CIOA 3S3RA 1PIPA 2DJFB 2E01A 3N3KA 3USVA 5PADA 2C0YA 3QSDA 1K3BB 4QRGA 4BPVA 2PREA 2FT2A 2FYEA 2XU3A 2P86A 1KHQA 1POPA 4OEMA 3AI8A 4YYUA 2YJCA 1JQPA 2DZYA 2YJBA 1MS6A 2FRQA 3OISA 4N4ZA 3IUTA 4X6IA 4N79A 4YYSA 2GFOA 1VJVA 3HWNA 4PADA 4XUIA 1CSBB 4Q8GA 2B1NA 2AUXA 4YVAA 1ME4A 2AYNA 4CDCB 3I06A 2DZZA 2HHNA 2O6XA 1PADA 4KLBA 1AECA 2P7UA 1FH0A 1O0EA 2PADA 2ARYA 1GMYA 4XR7A 1U9WA 3H8CA 4AXMA 3BOWA 4DMXA 2Y6EA 1AU0A 1CPJA 3N4CA 2HD5A 3KKUA 1YT7A 4QRVA 2PBHA 1M6DA 4W4UA 2Y5BA 1SNKA 5JH3A 1KFXL 1F2AA 2AS8A 1GLOA 3IHPA 2IBIA 1PBHA 1STFE 4QBBA 6PADA 4P6GA 5A24A 1Q6KA 3BWKA 1PPOA 2DCDA 1X9YA 2XU4A 1PCIA 3BPMA 1QXPA 3B79A 3CBKA 3CH3X 1QMYA 5CVNB 1KFUL 2JQGR 3WXFA 1EWOA 3IV2A 3PDFA 4QRXA 2R9FA 4X6JA 1EWMA 1CQDA 2DC9A 5CHTA 3ERVA 3S3QA 3PBHA 2DCCA 3LXSA 3PNRA 4WA6A 1BQIA 2FQ9A 5K16A 4PP1A 3KW9A 1MDWA 4I04A 3RVXA 1DEUA 4W5CA 2FRAA 4HWYA 1AU2A 3HHAA 1F2CA 3CH2X 1AYUA 4X6HA 5CVOB 2OZ2A 3M99A 1KHPA 1QDQA 1QOLA 3KX1A 1TU6A 4AXLA
chains in the Genus database with same CATH superfamily
1YALA 1KXRA 4CZWA 3BC3A 3K24A 3OF8A 3H89A 3K8UA 3HD3A 1CS8A 3H8BA 3OF9A 1YK8A 4CDEB 3IEJA 1BP4A 4ZUXU 9PAPA 2VHFA 2CB5A 2G8EA 5EGWA 4CDDB 1ZCMA 4MZOA 1EWLA 2YJ9A 3IMAA 1AU3A 1CV8A 3RVVA 3RVWA 2R9OA 3H7DA 1Y08A 5E6JA 4HXDB 1PPNA 4RY2A 1ICFA 1ME3A 4BQVA 3K9MA 2HH5A 2AUZA 2VHSA 2NQIA 1IWDA 2R9NA 2E03A 4I07A 1NB3A 2DC6A 3P5VA 1DKIA 4CDFB 4Q8HA 3E1ZB 2YJ2A 2AGAA 5FPWA 3MTVA 2DJGB 2R6NA 1PVJA 3QJ3A 1HUCB 5J94A 8PCHA 3PRPA 2R9MA 2JTCA 2B1MA 3TRKA 1U9QX 4W5BA 2AU1A 1PXVA 3V6EA 3P5XA 3W31A 2Z84A 4N8WA 2DCAA 5F02A 4BS6A 4RKXA 4YYQA 4OVZB 3LFYA 3PHWA 1NQCA 4REZA 4MSXA 4OELA 4BOUA 2G6DA 2E00A 3MTNA 4FIPA 3MHSA 4K7CA 1F2BA 1THEA 4D8EA 2AIMA 4YYVA 3IFUA 3O1GA 4YYWA 4RF0A 2NQAA 4G54A 4IUMA 1BGOA 3BPFA 1YZBA 1CJLA 2ATOA 4FK5A 4D8IA 3OQCA 4PP2E 2YJ8A 3KWBX 1S4VA 3ZNHA 2AVWA 3D6SA 5EF4A 3KFQA 1MIRA 2NQDB 1ZIVA 1Y4HA 5EZQA 1A6RA 3N3GA 4BS5A 3KWZA 2H7JA 3PW3A 3TMPA 1ITOA 3PHUA 1EF7A 5JA7A 3BCNA 2DCBA 3BB7A 1F29A 4XZXA 5CVMA 2P0RA 4FJCA 2F1GA 1ATKA 1TL9A 2AYOA 4ZTBA 4MI7A 3P5WA 3KSEA 3PRMA 2GHUA 4IP3A 4QH6A 3H6SA 1U5IA 3ZUAA 2NQGA 1CVZA 1NL6A 2F7DA 5KO3A 1XKGA 1SP4B 1MEGA 4A5UA 3OVXA 1AYVA 1GECE 4PI3A 3F75A 2BDZA 3P5UA 3MORA 5JZEA 2JQFR 2HWKA 2G8JA 3F5VA 4M0WA 4MM3B 2FUDA 4P6EA 3MHHA 3BY4A 4BSQA 1AIMA 3U8EA 3DF0A 4DMYA 2FTDA 3QT4A 1CTEA 2FO5A 1YVBA 4PT5A 4YYRA 1MHWA 4BOSA 3IOQA 1TLOA 7PCKA 3HHIA 1BY8A 4YV8A 2G7YA 2E02A 2IPPB 2XU1A 3CBJA 2OULA 3OVZA 3TNXA 4BOPA 1U9XA 3E9SA 3O0UA 4D8BA 3C0RA 3NHEA 2WBFX 2HXZA 3WXGA 4BOZA 1DF0A 1AU4A 2BTWB 1NPZA 3WXEA 4I05A 3GCBA 4OVZA 4WURA 1PE6A 2DC8A 2OP3A 1U9VA 3I3TA 2BDLA 1CB5A 3C9EA 2PNSA 1PPDA 1NB5A 1YK7A 3B21A 5EZSA 4MZSA 2ACTA 5CHVA 2XU5A 1EWPA 1AYWA 1PPPA 1NLJA 1VSNA 2DC7A 3V6CA 2R9CA 1GCBA 1MEMA 2CIOA 3S3RA 1PIPA 2DJFB 2E01A 3N3KA 3USVA 5PADA 2C0YA 3QSDA 1K3BB 4QRGA 4BPVA 2PREA 2FT2A 2FYEA 2XU3A 4RF1A 2P86A 1KHQA 1POPA 4OW0A 4OEMA 4GUAA 3AI8A 4YYUA 2YJCA 3W30A 1JQPA 2DZYA 2YJBA 1MS6A 2FRQA 3OISA 4N4ZA 3IUTA 4X6IA 4N79A 4YYSA 2GFOA 1VJVA 3HWNA 2BU3A 4PADA 3BBAA 4XUIA 3PT2A 1CSBB 4Q8GA 2B1NA 2AUXA 4YVAA 1ME4A 2AYNA 4CDCB 3I06A 3O65A 2DZZA 2HHNA 2O6XA 4P16A 1PADA 4KLBA 1AECA 3RNVA 2P7UA 4BOQA 1FH0A 1O0EA 2PADA 2ARYA 1GMYA 2FE8A 4XR7A 1U9WA 3H8CA 4AXMA 3BOWA 2J7QC 4DMXA 2Y6EA 1AU0A 1CPJA 3N4CA 2HD5A 3KKUA 1YT7A 4QRVA 2BTWA 2PBHA 1M6DA 4W4UA 2Y5BA 1SNKA 5JH3A 1KFXL 1F2AA 2AS8A 1GLOA 3IHPA 2IBIA 1PBHA 1STFE 4QBBA 6PADA 4P6GA 5A24A 1Q6KA 3BWKA 1PPOA 2JRIA 2DCDA 1X9YA 2XU4A 1PCIA 3BPMA 1QXPA 3B79A 3CBKA 3CH3X 1QMYA 5CVNB 1KFUL 2JQGR 3MP2A 3MJ5A 3WXFA 1EWOA 3IV2A 3PDFA 2UZJA 4QRXA 1UKFA 2R9FA 4X6JA 3PHXA 2J7QA 1EWMA 1CQDA 2DC9A 5CHTA 3ERVA 3S3QA 4R3DA 2DOSA 3PBHA 2DCCA 3LXSA 3PNRA 4WA6A 1BQIA 2FQ9A 5K16A 4PP1A 3KW9A 1MDWA 4I04A 3RVXA 1DEUA 4W5CA 2FRAA 4HWYA 1AU2A 3HHAA 1F2CA 3PSEA 3CH2X 1AYUA 4X6HA 5CVOB 2OZ2A 3M99A 4RNAA 1KHPA 1QDQA 1QOLA 3KX1A 1TU6A 4AXLA
chains in the Genus database with same CATH topology
1YALA 1KXRA 4CZWA 3BC3A 3K24A 3OF8A 3H89A 3K8UA 3HD3A 1CS8A 3H8BA 3OF9A 1YK8A 4CDEB 3IEJA 1BP4A 4ZUXU 9PAPA 2VHFA 2CB5A 2G8EA 2BSZA 5EGWA 4CDDB 1ZCMA 4MZOA 1EWLA 2YJ9A 3IMAA 1AU3A 1CV8A 3RVVA 3RVWA 2R9OA 3H7DA 1Y08A 1PPNA 4RY2A 1ICFA 1ME3A 4BQVA 3K9MA 2HH5A 2AUZA 2VHSA 1W5RA 2NQIA 1IWDA 2R9NA 4I07A 2E03A 1NB3A 2DC6A 3P5VA 4CDFB 4Q8HA 3E1ZB 2YJ2A 5FPWA 2DJGB 2R6NA 3QJ3A 1HUCB 5J94A 8PCHA 2R9MA 2B1MA 1U9QX 4W5BA 2AU1A 1PXVA 3V6EA 3P5XA 4N8WA 2DCAA 5F02A 4BS6A 4YYQA 3LFYA 1NQCA 4MSXA 4OELA 2G6DA 2E00A 3MTNA 4FIPA 3MHSA 4K7CA 1F2BA 1THEA 2AIMA 4YYVA 3O1GA 4YYWA 2NQAA 4G54A 1BGOA 3BPFA 1CJLA 2ATOA 4FK5A 4PP2E 2YJ8A 3KWBX 1S4VA 2AVWA 4NV8A 3D6SA 5EF4A 3KFQA 1MIRA 2NQDB 1ZIVA 1Y4HA 1A6RA 3N3GA 4BS5A 3KWZA 2H7JA 3PW3A 1ITOA 1EF7A 5JA7A 3BCNA 2DCBA 1F29A 5CVMA 2P0RA 4FJCA 2F1GA 1ATKA 1TL9A 4C5PA 2AYOA 3P5WA 3KSEA 2GHUA 4QH6A 3H6SA 1U5IA 3ZUAA 2NQGA 1CVZA 1NL6A 2F7DA 1XKGA 1SP4B 1MEGA 3OVXA 1AYVA 1GECE 4PI3A 3F75A 2BDZA 3P5UA 3MORA 2JQFR 2G8JA 3F5VA 2FUDA 4P6EA 3MHHA 4BSQA 1AIMA 3U8EA 3DF0A 4DMYA 2FTDA 3QT4A 1CTEA 2FO5A 1YVBA 4YYRA 1MHWA 3IOQA 1TLOA 7PCKA 3HHIA 1BY8A 4YV8A 2G7YA 2E02A 2IPPB 2XU1A 3CBJA 2OULA 3OVZA 3TNXA 1U9XA 3O0UA 3NHEA 2WBFX 2HXZA 3WXGA 1DF0A 1AU4A 1NPZA 3D9WA 3WXEA 4I05A 3GCBA 1PE6A 2DC8A 2OP3A 1U9VA 4GUZA 3I3TA 4BGFA 2BDLA 1CB5A 3C9EA 2PNSA 1PPDA 1NB5A 1YK7A 4MZSA 2ACTA 5CHVA 2XU5A 1EWPA 1AYWA 1PPPA 1NLJA 1VSNA 2DC7A 3V6CA 2R9CA 1GCBA 1MEMA 2CIOA 3S3RA 1PIPA 2DJFB 2E01A 3N3KA 3USVA 5PADA 2C0YA 3QSDA 1K3BB 4QRGA 4BPVA 2PREA 2FT2A 2FYEA 2XU3A 2P86A 1KHQA 1POPA 4OEMA 3AI8A 4YYUA 2YJCA 1JQPA 2DZYA 2YJBA 1MS6A 2FRQA 3OISA 4N4ZA 3IUTA 4X6IA 4N79A 4YYSA 2VFCA 2GFOA 1W4TA 1VJVA 3HWNA 4PADA 4XUIA 1CSBB 4Q8GA 2B1NA 2AUXA 4YVAA 1ME4A 2AYNA 4CDCB 3I06A 4B55A 2DZZA 2HHNA 2O6XA 1PADA 4KLBA 1AECA 1GX3A 2P7UA 1FH0A 1O0EA 2PADA 2ARYA 1GMYA 4XR7A 1U9WA 3H8CA 4AXMA 3BOWA 4DMXA 2Y6EA 1AU0A 1CPJA 3N4CA 4NV7A 2HD5A 3KKUA 1YT7A 4QRVA 2VFBA 2PBHA 1M6DA 4W4UA 1E2TA 2Y5BA 1SNKA 5JH3A 1KFXL 1F2AA 2AS8A 1GLOA 3IHPA 2IBIA 1PBHA 1STFE 4QBBA 6PADA 4P6GA 5A24A 1Q6KA 3BWKA 1PPOA 2DCDA 1X9YA 2XU4A 1PCIA 3BPMA 1QXPA 3B79A 3CBKA 3CH3X 1QMYA 5CVNB 1KFUL 2JQGR 3WXFA 1EWOA 3IV2A 3PDFA 4QRXA 2R9FA 4X6JA 1EWMA 1CQDA 2DC9A 5CHTA 3ERVA 3S3QA 1W6FA 3PBHA 2DCCA 3LXSA 3PNRA 3LTWA 4WA6A 1BQIA 2FQ9A 5K16A 4PP1A 3KW9A 1MDWA 4I04A 3RVXA 1DEUA 4W5CA 2FRAA 4HWYA 1AU2A 3HHAA 1F2CA 3CH2X 1AYUA 4X6HA 5CVOB 2OZ2A 3M99A 1KHPA 1QDQA 1QOLA 3KX1A 1TU6A 4AXLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YAL A;  1KXR A;  4CZW A;  3BC3 A;  3K24 A;  3OF8 A;  3H89 A;  3K8U A;  3HD3 A;  1CS8 A;  3H8B A;  3OF9 A;  1YK8 A;  4CDE B;  3IEJ A;  1BP4 A;  4ZUX U;  9PAP A;  2VHF A;  2CB5 A;  2G8E A;  5EGW A;  4CDD B;  1ZCM A;  4MZO A;  1EWL A;  2YJ9 A;  3IMA A;  1AU3 A;  1CV8 A;  3RVV A;  3RVW A;  2R9O A;  3H7D A;  1Y08 A;  1PPN A;  4RY2 A;  1ICF A;  1ME3 A;  4BQV A;  3K9M A;  2HH5 A;  2AUZ A;  2VHS A;  2NQI A;  1IWD A;  2R9N A;  4I07 A;  2E03 A;  1NB3 A;  2DC6 A;  3P5V A;  4CDF B;  4Q8H A;  3E1Z B;  2YJ2 A;  5FPW A;  2DJG B;  2R6N A;  3QJ3 A;  1HUC B;  5J94 A;  8PCH A;  2R9M A;  2B1M A;  1U9Q X;  4W5B A;  2AU1 A;  1PXV A;  3V6E A;  3P5X A;  4N8W A;  2DCA A;  5F02 A;  4BS6 A;  4YYQ A;  3LFY A;  1NQC A;  4MSX A;  4OEL A;  2G6D A;  2E00 A;  3MTN A;  4FIP A;  3MHS A;  4K7C A;  1F2B A;  1THE A;  2AIM A;  4YYV A;  3O1G A;  4YYW A;  2NQA A;  4G54 A;  1BGO A;  3BPF A;  1CJL A;  2ATO A;  4FK5 A;  4PP2 E;  2YJ8 A;  3KWB X;  1S4V A;  2AVW A;  3D6S A;  5EF4 A;  3KFQ A;  1MIR A;  2NQD B;  1ZIV A;  1Y4H A;  1A6R A;  3N3G A;  4BS5 A;  3KWZ A;  2H7J A;  3PW3 A;  1ITO A;  1EF7 A;  5JA7 A;  3BCN A;  2DCB A;  1F29 A;  5CVM A;  2P0R A;  4FJC A;  2F1G A;  1ATK A;  1TL9 A;  2AYO A;  3P5W A;  3KSE A;  2GHU A;  4QH6 A;  3H6S A;  1U5I A;  3ZUA A;  2NQG A;  1CVZ A;  1NL6 A;  2F7D A;  1XKG A;  1SP4 B;  1MEG A;  3OVX A;  1AYV A;  1GEC E;  4PI3 A;  3F75 A;  2BDZ A;  3P5U A;  3MOR A;  2JQF R;  2G8J A;  3F5V A;  2FUD A;  4P6E A;  3MHH A;  4BSQ A;  1AIM A;  3U8E A;  3DF0 A;  4DMY A;  2FTD A;  3QT4 A;  1CTE A;  2FO5 A;  1YVB A;  4YYR A;  1MHW A;  3IOQ A;  1TLO A;  7PCK A;  3HHI A;  1BY8 A;  4YV8 A;  2G7Y A;  2E02 A;  2IPP B;  2XU1 A;  3CBJ A;  2OUL A;  3OVZ A;  3TNX A;  1U9X A;  3O0U A;  3NHE A;  2WBF X;  2HXZ A;  3WXG A;  1DF0 A;  1AU4 A;  1NPZ A;  3WXE A;  4I05 A;  3GCB A;  1PE6 A;  2DC8 A;  2OP3 A;  1U9V A;  3I3T A;  2BDL A;  1CB5 A;  3C9E A;  2PNS A;  1PPD A;  1NB5 A;  1YK7 A;  4MZS A;  2ACT A;  5CHV A;  2XU5 A;  1EWP A;  1AYW A;  1PPP A;  1NLJ A;  1VSN A;  2DC7 A;  3V6C A;  2R9C A;  1GCB A;  1MEM A;  2CIO A;  3S3R A;  1PIP A;  2DJF B;  2E01 A;  3N3K A;  3USV A;  5PAD A;  2C0Y A;  3QSD A;  1K3B B;  4QRG A;  4BPV A;  2PRE A;  2FT2 A;  2FYE A;  2XU3 A;  2P86 A;  1KHQ A;  1POP A;  4OEM A;  3AI8 A;  4YYU A;  2YJC A;  1JQP A;  2DZY A;  2YJB A;  1MS6 A;  2FRQ A;  3OIS A;  4N4Z A;  3IUT A;  4X6I A;  4N79 A;  4YYS A;  2GFO A;  1VJV A;  3HWN A;  4PAD A;  4XUI A;  1CSB B;  4Q8G A;  2B1N A;  2AUX A;  4YVA A;  1ME4 A;  2AYN A;  4CDC B;  3I06 A;  2DZZ A;  2HHN A;  2O6X A;  1PAD A;  4KLB A;  1AEC A;  2P7U A;  1FH0 A;  1O0E A;  2PAD A;  2ARY A;  1GMY A;  4XR7 A;  1U9W A;  3H8C A;  4AXM A;  3BOW A;  4DMX A;  2Y6E A;  1AU0 A;  1CPJ A;  3N4C A;  2HD5 A;  3KKU A;  1YT7 A;  4QRV A;  2PBH A;  1M6D A;  4W4U A;  2Y5B A;  1SNK A;  5JH3 A;  1KFX L;  1F2A A;  2AS8 A;  1GLO A;  3IHP A;  2IBI A;  1PBH A;  1STF E;  4QBB A;  6PAD A;  4P6G A;  5A24 A;  1Q6K A;  3BWK A;  1PPO A;  2DCD A;  1X9Y A;  2XU4 A;  1PCI A;  3BPM A;  1QXP A;  3B79 A;  3CBK A;  3CH3 X;  1QMY A;  5CVN B;  1KFU L;  2JQG R;  3WXF A;  1EWO A;  3IV2 A;  3PDF A;  4QRX A;  2R9F A;  4X6J A;  1EWM A;  1CQD A;  2DC9 A;  5CHT A;  3ERV A;  3S3Q A;  3PBH A;  2DCC A;  3LXS A;  3PNR A;  4WA6 A;  1BQI A;  2FQ9 A;  5K16 A;  4PP1 A;  3KW9 A;  1MDW A;  4I04 A;  3RVX A;  1DEU A;  4W5C A;  2FRA A;  4HWY A;  1AU2 A;  3HHA A;  1F2C A;  3CH2 X;  1AYU A;  4X6H A;  5CVO B;  2OZ2 A;  3M99 A;  1KHP A;  1QDQ A;  1QOL A;  3KX1 A;  1TU6 A;  4AXL A; 
#chains in the Genus database with same CATH topology
 1YAL A;  1KXR A;  4CZW A;  3BC3 A;  3K24 A;  3OF8 A;  3H89 A;  3K8U A;  3HD3 A;  1CS8 A;  3H8B A;  3OF9 A;  1YK8 A;  4CDE B;  3IEJ A;  1BP4 A;  4ZUX U;  9PAP A;  2VHF A;  2CB5 A;  2G8E A;  5EGW A;  4CDD B;  1ZCM A;  4MZO A;  1EWL A;  2YJ9 A;  3IMA A;  1AU3 A;  1CV8 A;  3RVV A;  3RVW A;  2R9O A;  3H7D A;  1Y08 A;  5E6J A;  4HXD B;  1PPN A;  4RY2 A;  1ICF A;  1ME3 A;  4BQV A;  3K9M A;  2HH5 A;  2AUZ A;  2VHS A;  2NQI A;  1IWD A;  2R9N A;  2E03 A;  4I07 A;  1NB3 A;  2DC6 A;  3P5V A;  1DKI A;  4CDF B;  4Q8H A;  3E1Z B;  2YJ2 A;  2AGA A;  5FPW A;  3MTV A;  2DJG B;  2R6N A;  1PVJ A;  3QJ3 A;  1HUC B;  5J94 A;  8PCH A;  3PRP A;  2R9M A;  2JTC A;  2B1M A;  3TRK A;  1U9Q X;  4W5B A;  2AU1 A;  1PXV A;  3V6E A;  3P5X A;  3W31 A;  2Z84 A;  4N8W A;  2DCA A;  5F02 A;  4BS6 A;  4RKX A;  4YYQ A;  4OVZ B;  3LFY A;  3PHW A;  1NQC A;  4REZ A;  4MSX A;  4OEL A;  4BOU A;  2G6D A;  2E00 A;  3MTN A;  4FIP A;  3MHS A;  4K7C A;  1F2B A;  1THE A;  4D8E A;  2AIM A;  4YYV A;  3IFU A;  3O1G A;  4YYW A;  4RF0 A;  2NQA A;  4G54 A;  4IUM A;  1BGO A;  3BPF A;  1YZB A;  1CJL A;  2ATO A;  4FK5 A;  4D8I A;  3OQC A;  4PP2 E;  2YJ8 A;  3KWB X;  1S4V A;  3ZNH A;  2AVW A;  3D6S A;  5EF4 A;  3KFQ A;  1MIR A;  2NQD B;  1ZIV A;  1Y4H A;  5EZQ A;  1A6R A;  3N3G A;  4BS5 A;  3KWZ A;  2H7J A;  3PW3 A;  3TMP A;  1ITO A;  3PHU A;  1EF7 A;  5JA7 A;  3BCN A;  2DCB A;  3BB7 A;  1F29 A;  4XZX A;  5CVM A;  2P0R A;  4FJC A;  2F1G A;  1ATK A;  1TL9 A;  2AYO A;  4ZTB A;  4MI7 A;  3P5W A;  3KSE A;  3PRM A;  2GHU A;  4IP3 A;  4QH6 A;  3H6S A;  1U5I A;  3ZUA A;  2NQG A;  1CVZ A;  1NL6 A;  2F7D A;  5KO3 A;  1XKG A;  1SP4 B;  1MEG A;  4A5U A;  3OVX A;  1AYV A;  1GEC E;  4PI3 A;  3F75 A;  2BDZ A;  3P5U A;  3MOR A;  5JZE A;  2JQF R;  2HWK A;  2G8J A;  3F5V A;  4M0W A;  4MM3 B;  2FUD A;  4P6E A;  3MHH A;  3BY4 A;  4BSQ A;  1AIM A;  3U8E A;  3DF0 A;  4DMY A;  2FTD A;  3QT4 A;  1CTE A;  2FO5 A;  1YVB A;  4PT5 A;  4YYR A;  1MHW A;  4BOS A;  3IOQ A;  1TLO A;  7PCK A;  3HHI A;  1BY8 A;  4YV8 A;  2G7Y A;  2E02 A;  2IPP B;  2XU1 A;  3CBJ A;  2OUL A;  3OVZ A;  3TNX A;  4BOP A;  1U9X A;  3E9S A;  3O0U A;  4D8B A;  3C0R A;  3NHE A;  2WBF X;  2HXZ A;  3WXG A;  4BOZ A;  1DF0 A;  1AU4 A;  2BTW B;  1NPZ A;  3WXE A;  4I05 A;  3GCB A;  4OVZ A;  4WUR A;  1PE6 A;  2DC8 A;  2OP3 A;  1U9V A;  3I3T A;  2BDL A;  1CB5 A;  3C9E A;  2PNS A;  1PPD A;  1NB5 A;  1YK7 A;  3B21 A;  5EZS A;  4MZS A;  2ACT A;  5CHV A;  2XU5 A;  1EWP A;  1AYW A;  1PPP A;  1NLJ A;  1VSN A;  2DC7 A;  3V6C A;  2R9C A;  1GCB A;  1MEM A;  2CIO A;  3S3R A;  1PIP A;  2DJF B;  2E01 A;  3N3K A;  3USV A;  5PAD A;  2C0Y A;  3QSD A;  1K3B B;  4QRG A;  4BPV A;  2PRE A;  2FT2 A;  2FYE A;  2XU3 A;  4RF1 A;  2P86 A;  1KHQ A;  1POP A;  4OW0 A;  4OEM A;  4GUA A;  3AI8 A;  4YYU A;  2YJC A;  3W30 A;  1JQP A;  2DZY A;  2YJB A;  1MS6 A;  2FRQ A;  3OIS A;  4N4Z A;  3IUT A;  4X6I A;  4N79 A;  4YYS A;  2GFO A;  1VJV A;  3HWN A;  2BU3 A;  4PAD A;  3BBA A;  4XUI A;  3PT2 A;  1CSB B;  4Q8G A;  2B1N A;  2AUX A;  4YVA A;  1ME4 A;  2AYN A;  4CDC B;  3I06 A;  3O65 A;  2DZZ A;  2HHN A;  2O6X A;  4P16 A;  1PAD A;  4KLB A;  1AEC A;  3RNV A;  2P7U A;  4BOQ A;  1FH0 A;  1O0E A;  2PAD A;  2ARY A;  1GMY A;  2FE8 A;  4XR7 A;  1U9W A;  3H8C A;  4AXM A;  3BOW A;  2J7Q C;  4DMX A;  2Y6E A;  1AU0 A;  1CPJ A;  3N4C A;  2HD5 A;  3KKU A;  1YT7 A;  4QRV A;  2BTW A;  2PBH A;  1M6D A;  4W4U A;  2Y5B A;  1SNK A;  5JH3 A;  1KFX L;  1F2A A;  2AS8 A;  1GLO A;  3IHP A;  2IBI A;  1PBH A;  1STF E;  4QBB A;  6PAD A;  4P6G A;  5A24 A;  1Q6K A;  3BWK A;  1PPO A;  2JRI A;  2DCD A;  1X9Y A;  2XU4 A;  1PCI A;  3BPM A;  1QXP A;  3B79 A;  3CBK A;  3CH3 X;  1QMY A;  5CVN B;  1KFU L;  2JQG R;  3MP2 A;  3MJ5 A;  3WXF A;  1EWO A;  3IV2 A;  3PDF A;  2UZJ A;  4QRX A;  1UKF A;  2R9F A;  4X6J A;  3PHX A;  2J7Q A;  1EWM A;  1CQD A;  2DC9 A;  5CHT A;  3ERV A;  3S3Q A;  4R3D A;  2DOS A;  3PBH A;  2DCC A;  3LXS A;  3PNR A;  4WA6 A;  1BQI A;  2FQ9 A;  5K16 A;  4PP1 A;  3KW9 A;  1MDW A;  4I04 A;  3RVX A;  1DEU A;  4W5C A;  2FRA A;  4HWY A;  1AU2 A;  3HHA A;  1F2C A;  3PSE A;  3CH2 X;  1AYU A;  4X6H A;  5CVO B;  2OZ2 A;  3M99 A;  4RNA A;  1KHP A;  1QDQ A;  1QOL A;  3KX1 A;  1TU6 A;  4AXL A; 
#chains in the Genus database with same CATH homology
 1YAL A;  1KXR A;  4CZW A;  3BC3 A;  3K24 A;  3OF8 A;  3H89 A;  3K8U A;  3HD3 A;  1CS8 A;  3H8B A;  3OF9 A;  1YK8 A;  4CDE B;  3IEJ A;  1BP4 A;  4ZUX U;  9PAP A;  2VHF A;  2CB5 A;  2G8E A;  2BSZ A;  5EGW A;  4CDD B;  1ZCM A;  4MZO A;  1EWL A;  2YJ9 A;  3IMA A;  1AU3 A;  1CV8 A;  3RVV A;  3RVW A;  2R9O A;  3H7D A;  1Y08 A;  1PPN A;  4RY2 A;  1ICF A;  1ME3 A;  4BQV A;  3K9M A;  2HH5 A;  2AUZ A;  2VHS A;  1W5R A;  2NQI A;  1IWD A;  2R9N A;  4I07 A;  2E03 A;  1NB3 A;  2DC6 A;  3P5V A;  4CDF B;  4Q8H A;  3E1Z B;  2YJ2 A;  5FPW A;  2DJG B;  2R6N A;  3QJ3 A;  1HUC B;  5J94 A;  8PCH A;  2R9M A;  2B1M A;  1U9Q X;  4W5B A;  2AU1 A;  1PXV A;  3V6E A;  3P5X A;  4N8W A;  2DCA A;  5F02 A;  4BS6 A;  4YYQ A;  3LFY A;  1NQC A;  4MSX A;  4OEL A;  2G6D A;  2E00 A;  3MTN A;  4FIP A;  3MHS A;  4K7C A;  1F2B A;  1THE A;  2AIM A;  4YYV A;  3O1G A;  4YYW A;  2NQA A;  4G54 A;  1BGO A;  3BPF A;  1CJL A;  2ATO A;  4FK5 A;  4PP2 E;  2YJ8 A;  3KWB X;  1S4V A;  2AVW A;  4NV8 A;  3D6S A;  5EF4 A;  3KFQ A;  1MIR A;  2NQD B;  1ZIV A;  1Y4H A;  1A6R A;  3N3G A;  4BS5 A;  3KWZ A;  2H7J A;  3PW3 A;  1ITO A;  1EF7 A;  5JA7 A;  3BCN A;  2DCB A;  1F29 A;  5CVM A;  2P0R A;  4FJC A;  2F1G A;  1ATK A;  1TL9 A;  4C5P A;  2AYO A;  3P5W A;  3KSE A;  2GHU A;  4QH6 A;  3H6S A;  1U5I A;  3ZUA A;  2NQG A;  1CVZ A;  1NL6 A;  2F7D A;  1XKG A;  1SP4 B;  1MEG A;  3OVX A;  1AYV A;  1GEC E;  4PI3 A;  3F75 A;  2BDZ A;  3P5U A;  3MOR A;  2JQF R;  2G8J A;  3F5V A;  2FUD A;  4P6E A;  3MHH A;  4BSQ A;  1AIM A;  3U8E A;  3DF0 A;  4DMY A;  2FTD A;  3QT4 A;  1CTE A;  2FO5 A;  1YVB A;  4YYR A;  1MHW A;  3IOQ A;  1TLO A;  7PCK A;  3HHI A;  1BY8 A;  4YV8 A;  2G7Y A;  2E02 A;  2IPP B;  2XU1 A;  3CBJ A;  2OUL A;  3OVZ A;  3TNX A;  1U9X A;  3O0U A;  3NHE A;  2WBF X;  2HXZ A;  3WXG A;  1DF0 A;  1AU4 A;  1NPZ A;  3D9W A;  3WXE A;  4I05 A;  3GCB A;  1PE6 A;  2DC8 A;  2OP3 A;  1U9V A;  4GUZ A;  3I3T A;  4BGF A;  2BDL A;  1CB5 A;  3C9E A;  2PNS A;  1PPD A;  1NB5 A;  1YK7 A;  4MZS A;  2ACT A;  5CHV A;  2XU5 A;  1EWP A;  1AYW A;  1PPP A;  1NLJ A;  1VSN A;  2DC7 A;  3V6C A;  2R9C A;  1GCB A;  1MEM A;  2CIO A;  3S3R A;  1PIP A;  2DJF B;  2E01 A;  3N3K A;  3USV A;  5PAD A;  2C0Y A;  3QSD A;  1K3B B;  4QRG A;  4BPV A;  2PRE A;  2FT2 A;  2FYE A;  2XU3 A;  2P86 A;  1KHQ A;  1POP A;  4OEM A;  3AI8 A;  4YYU A;  2YJC A;  1JQP A;  2DZY A;  2YJB A;  1MS6 A;  2FRQ A;  3OIS A;  4N4Z A;  3IUT A;  4X6I A;  4N79 A;  4YYS A;  2VFC A;  2GFO A;  1W4T A;  1VJV A;  3HWN A;  4PAD A;  4XUI A;  1CSB B;  4Q8G A;  2B1N A;  2AUX A;  4YVA A;  1ME4 A;  2AYN A;  4CDC B;  3I06 A;  4B55 A;  2DZZ A;  2HHN A;  2O6X A;  1PAD A;  4KLB A;  1AEC A;  1GX3 A;  2P7U A;  1FH0 A;  1O0E A;  2PAD A;  2ARY A;  1GMY A;  4XR7 A;  1U9W A;  3H8C A;  4AXM A;  3BOW A;  4DMX A;  2Y6E A;  1AU0 A;  1CPJ A;  3N4C A;  4NV7 A;  2HD5 A;  3KKU A;  1YT7 A;  4QRV A;  2VFB A;  2PBH A;  1M6D A;  4W4U A;  1E2T A;  2Y5B A;  1SNK A;  5JH3 A;  1KFX L;  1F2A A;  2AS8 A;  1GLO A;  3IHP A;  2IBI A;  1PBH A;  1STF E;  4QBB A;  6PAD A;  4P6G A;  5A24 A;  1Q6K A;  3BWK A;  1PPO A;  2DCD A;  1X9Y A;  2XU4 A;  1PCI A;  3BPM A;  1QXP A;  3B79 A;  3CBK A;  3CH3 X;  1QMY A;  5CVN B;  1KFU L;  2JQG R;  3WXF A;  1EWO A;  3IV2 A;  3PDF A;  4QRX A;  2R9F A;  4X6J A;  1EWM A;  1CQD A;  2DC9 A;  5CHT A;  3ERV A;  3S3Q A;  1W6F A;  3PBH A;  2DCC A;  3LXS A;  3PNR A;  3LTW A;  4WA6 A;  1BQI A;  2FQ9 A;  5K16 A;  4PP1 A;  3KW9 A;  1MDW A;  4I04 A;  3RVX A;  1DEU A;  4W5C A;  2FRA A;  4HWY A;  1AU2 A;  3HHA A;  1F2C A;  3CH2 X;  1AYU A;  4X6H A;  5CVO B;  2OZ2 A;  3M99 A;  1KHP A;  1QDQ A;  1QOL A;  3KX1 A;  1TU6 A;  4AXL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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