1BY8A

The crystal structure of human procathepsin k
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
310
structure length
310
Chain Sequence
EILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human procathepsin K.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROTEIN (PROCATHEPSIN K)
total genus 82
structure length 310
sequence length 310
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 1998-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1by8A00
2HH5A 3WXFA 1X9YA 1THEA 9PAPA 2IBIA 2E03A 3HHIA 2AYOA 2P7UA 5A24A 2XU4A 4QRXA 4MZSA 4DMYA 1AECA 4MZOA 3WXEA 2R9MA 5PADA 3OISA 4CZWA 4G54A 4X6HA 1CPJA 3K9MA 2XU5A 3BC3A 2PBHA 3F75A 4N4ZA 1NQCA 3ERVA 3OF9A 2BDZA 3USVA 1CS8A 1F2CA 2AUZA 1ZCMA 4CDCB 1VSNA 2HXZA 7PCKA 1SNKA 1IWDA 1KXRA 3PDFA 3KSEA 2FO5A 2FYEA 1NPZA 2PREA 1MEGA 1PPPA 1M6DA 2OP3A 3H8BA 4YYQA 5CHVA 2FQ9A 1ATKA 4ZUXU 4YYVA 1ITOA 1JQPA 5CVOB 1PPNA 4QH6A 1U9WA 1TU6A 2NQDB 3O1GA 2DZYA 2ARYA 1QOLA 4OELA 1ME3A 1PIPA 2JQFR 3N4CA 1KFUL 2HD5A 1YALA 5K16A 1ME4A 3BCNA 2ATOA 4QRGA 1QXPA 1MHWA 2JQGR 4FK5A 2YJ2A 2R9CA 2GHUA 4RY2A 2H7JA 1CB5A 1AU0A 2NQAA 3KWZA 3H8CA 3MHHA 1CV8A 2DJGB 4PI3A 3OVXA 1MEMA 4W5BA 2P0RA 4KLBA 1POPA 2C0YA 3BPFA 3PNRA 2E00A 4XR7A 1EWOA 2FUDA 3KFQA 4X6JA 1BGOA 1F29A 4MSXA 4AXLA 3V6EA 1AYUA 3B79A 3LXSA 3H89A 3AI8A 3E1ZB 2G7YA 1ICFA 1AYVA 1GECE 2R9NA 1PXVA 1YVBA 1PADA 2G6DA 4I07A 3BPMA 4CDFB 1NLJA 3BOWA 4BS5A 4HWYA 5CHTA 3RVWA 1Y4HA 1QDQA 4N8WA 2AIMA 2E01A 2FRAA 5JA7A 3P5UA 5CVMA 1MDWA 3P5XA 4WA6A 2AS8A 1NL6A 2F7DA 4DMXA 2YJCA 2Y6EA 5JH3A 1STFE 4BQVA 1O0EA 1BP4A 1AIMA 1XKGA 3GCBA 2OZ2A 3NHEA 5EGWA 3PW3A 2VHSA 2DZZA 1YT7A 3CH3X 3TNXA 4P6EA 4Q8HA 2FRQA 3DF0A 2XU3A 4X6IA 2DCCA 1YK7A 2DCAA 1EWPA 1U9VA 1PE6A 1DEUA 3H6SA 3HHAA 2Y5BA 1CJLA 4QBBA 1S4VA 4FIPA 4OEMA 2XU1A 1EWMA 2PADA 4W5CA 2R9FA 2B1NA 2GFOA 3CBKA 1NB5A 2G8EA 3MHSA 3OVZA 3V6CA 1YK8A 3IMAA 3O0UA 3IUTA 1BQIA 2DCDA 6PADA 2NQIA 1CTEA 3D6SA 4YVAA 2P86A 1K3BB 2YJ9A 4YV8A 1KFXL 1GMYA 5FPWA 2YJBA 2WBFX 2E02A 2F1GA 2CB5A 1AYWA 1AU4A 3RVXA 3N3GA 1AU2A 1KHQA 1GCBA 1U5IA 1Y08A 1KHPA 2IPPB 3BWKA 1PCIA 2DC7A 1TLOA 1PPDA 1FH0A 4PP2E 2DC8A 2R9OA 3WXGA 3LFYA 1MS6A 1CVZA 5EF4A 1AU3A 2ACTA 2DCBA 3IV2A 2O6XA 5F02A 2NQGA 4CDEB 1SP4B 3K24A 1EWLA 3MTNA 4XUIA 2VHFA 3S3RA 3KW9A 4PP1A 2BDLA 2AVWA 2B1MA 2HHNA 4YYUA 1DF0A 2DC6A 1U9QX 3RVVA 4YYSA 2AYNA 2DC9A 3HD3A 1TL9A 2DJFB 4YYWA 3H7DA 3P5WA 2FTDA 3F5VA 3CH2X 4YYRA 3S3QA 3I06A 2R6NA 1PPOA 5CVNB 4K7CA 8PCHA 3P5VA 4CDDB 3QSDA 3M99A 3ZUAA 3KKUA 1Q6KA 4BSQA 1PBHA 4AXMA 3U8EA 1U9XA 1ZIVA 2CIOA 4P6GA 3HWNA 3IOQA 4Q8GA 1F2AA 1VJVA 3PBHA 4PADA 1GLOA 2AU1A 4FJCA 4BS6A 2YJ8A 1EF7A 1A6RA 1F2BA 2PNSA 3KWBX 3CBJA 1HUCB 4QRVA 2G8JA 3MORA 3KX1A 3QJ3A 3C9EA 3I3TA 4W4UA 1BY8A 2FT2A 3QT4A 2AUXA 3OF8A 3IHPA 1CQDA 4I05A 4BPVA 4N79A 5J94A 1MIRA 2OULA 1CSBB 3IEJA 3K8UA 1QMYA 4I04A 1NB3A 3N3KA
chains in the Genus database with same CATH superfamily
2HH5A 3WXFA 1X9YA 4IP3A 4P16A 1THEA 9PAPA 2IBIA 1UKFA 2E03A 2JRIA 3HHIA 2AYOA 2P7UA 5A24A 2XU4A 4QRXA 4MZSA 4DMYA 1AECA 4MZOA 3WXEA 2R9MA 5PADA 3TRKA 3OISA 3TMPA 4CZWA 4G54A 4X6HA 1CPJA 4BOSA 3K9MA 2XU5A 3BC3A 2PBHA 3F75A 4N4ZA 1NQCA 3ERVA 3OF9A 2BDZA 3USVA 1CS8A 4D8EA 1F2CA 2AUZA 1ZCMA 3RNVA 1VSNA 4CDCB 2HXZA 7PCKA 1SNKA 1IWDA 4BOZA 1KXRA 3PDFA 3KSEA 2FO5A 2FYEA 1NPZA 2PREA 1MEGA 1PPPA 1M6DA 2OP3A 3H8BA 4YYQA 5CHVA 2FQ9A 1ATKA 4ZUXU 4YYVA 1ITOA 1JQPA 5CVOB 5E6JA 1PPNA 4QH6A 4GUAA 1U9WA 1TU6A 2NQDB 3O1GA 2DZYA 4IUMA 2ARYA 1QOLA 4OELA 1ME3A 1PIPA 2JQFR 4M0WA 3N4CA 1KFUL 2HD5A 3PT2A 1YALA 5K16A 5KO3A 1ME4A 3BCNA 2ATOA 4QRGA 1QXPA 1MHWA 2JQGR 4FK5A 2YJ2A 2R9CA 2GHUA 4RKXA 4RY2A 2H7JA 1CB5A 3OQCA 4OVZA 1AU0A 2NQAA 4WURA 3KWZA 3H8CA 3MHHA 1CV8A 2DJGB 4RF1A 4D8BA 4PI3A 3OVXA 1MEMA 4W5BA 2P0RA 3BY4A 4KLBA 1POPA 2C0YA 3BPFA 3PNRA 2E00A 3BB7A 4XR7A 1EWOA 2FUDA 3KFQA 3PRMA 4X6JA 1BGOA 1F29A 4MSXA 4AXLA 3V6EA 1AYUA 3B79A 3LXSA 3H89A 3AI8A 3E1ZB 4RNAA 2G7YA 1ICFA 1AYVA 1GECE 2R9NA 1PXVA 1YVBA 1PADA 2G6DA 2UZJA 4I07A 2AGAA 3BPMA 4CDFB 4ZTBA 1NLJA 3BOWA 4BS5A 4HWYA 5CHTA 3IFUA 3BBAA 3RVWA 1Y4HA 1QDQA 2BU3A 4N8WA 2AIMA 2E01A 2FRAA 5JA7A 3P5UA 4MI7A 5CVMA 1MDWA 2Z84A 3P5XA 4WA6A 2FE8A 4XZXA 2AS8A 1NL6A 1YZBA 2F7DA 4DMXA 2YJCA 2Y6EA 5JH3A 1STFE 4BQVA 1O0EA 4OW0A 1BP4A 1AIMA 4OVZB 1XKGA 3GCBA 2OZ2A 3NHEA 3MTVA 3PW3A 5EGWA 2HWKA 2DZZA 2VHSA 1YT7A 3CH3X 3TNXA 4P6EA 4Q8HA 2FRQA 3DF0A 3C0RA 2XU3A 3PHUA 1PVJA 4X6IA 2DCCA 1YK7A 2DCAA 1EWPA 1U9VA 1PE6A 5JZEA 1DEUA 3H6SA 3PHWA 2DOSA 3HHAA 2Y5BA 1CJLA 4QBBA 1S4VA 4FIPA 4OEMA 2XU1A 1EWMA 2PADA 4PT5A 4W5CA 3PHXA 2R9FA 2B1NA 2GFOA 3CBKA 1NB5A 2J7QA 2G8EA 3MHSA 3OVZA 3V6CA 1YK8A 3IMAA 3O0UA 3IUTA 1BQIA 2DCDA 6PADA 2NQIA 4A5UA 1CTEA 3W31A 3D6SA 4YVAA 2P86A 1K3BB 2YJ9A 4YV8A 1KFXL 1GMYA 5FPWA 2YJBA 2WBFX 2E02A 3MP2A 2F1GA 2CB5A 1AYWA 1AU4A 3RVXA 3N3GA 1AU2A 1KHQA 3O65A 1GCBA 1U5IA 1Y08A 1KHPA 2IPPB 3BWKA 1PCIA 2DC7A 1TLOA 4D8IA 1PPDA 1FH0A 4PP2E 2DC8A 2R9OA 2BTWB 3WXGA 3LFYA 1MS6A 1CVZA 4REZA 5EF4A 1AU3A 2ACTA 2DCBA 3IV2A 2O6XA 5F02A 2NQGA 3W30A 4CDEB 1SP4B 4R3DA 3K24A 1EWLA 5EZSA 3ZNHA 3MTNA 4XUIA 2VHFA 3S3RA 3KW9A 4PP1A 4BOQA 2BDLA 2AVWA 2B1MA 2HHNA 4YYUA 1DF0A 2DC6A 1U9QX 3RVVA 4YYSA 2AYNA 2DC9A 3HD3A 1TL9A 2DJFB 4YYWA 3H7DA 3P5WA 2FTDA 3F5VA 3CH2X 2BTWA 4YYRA 3S3QA 3PRPA 2JTCA 3E9SA 3I06A 2R6NA 1PPOA 5CVNB 4K7CA 8PCHA 3P5VA 4CDDB 3QSDA 3PSEA 3M99A 3ZUAA 3KKUA 1Q6KA 4BSQA 1PBHA 4AXMA 3U8EA 1U9XA 1ZIVA 1DKIA 2CIOA 4P6GA 3HWNA 3IOQA 4Q8GA 1F2AA 1VJVA 3PBHA 4PADA 1GLOA 4MM3B 2AU1A 4FJCA 4BS6A 5EZQA 2YJ8A 1EF7A 1A6RA 1F2BA 2PNSA 4BOPA 3KWBX 3CBJA 1HUCB 4QRVA 2G8JA 3MORA 3KX1A 3QJ3A 3C9EA 3I3TA 4W4UA 1BY8A 2FT2A 3B21A 2AUXA 3QT4A 3OF8A 4RF0A 3IHPA 1CQDA 3MJ5A 4I05A 4BOUA 4BPVA 4N79A 5J94A 1MIRA 4HXDB 2OULA 1CSBB 2J7QC 3IEJA 3K8UA 1QMYA 4I04A 1NB3A 3N3KA
chains in the Genus database with same CATH topology
2HH5A 3WXFA 1X9YA 1THEA 9PAPA 2IBIA 2E03A 3HHIA 2AYOA 2P7UA 5A24A 2XU4A 4QRXA 4MZSA 4DMYA 1AECA 4MZOA 3WXEA 2R9MA 5PADA 3OISA 4CZWA 4G54A 4X6HA 1CPJA 3K9MA 2XU5A 3BC3A 2PBHA 3F75A 4N4ZA 1NQCA 3ERVA 3OF9A 2BDZA 3USVA 1CS8A 1F2CA 4BGFA 2AUZA 1ZCMA 4CDCB 1VSNA 2HXZA 7PCKA 1SNKA 1IWDA 1KXRA 3PDFA 3KSEA 4C5PA 2FO5A 2FYEA 1NPZA 2PREA 1MEGA 1PPPA 1M6DA 2OP3A 3H8BA 4YYQA 5CHVA 1W4TA 2FQ9A 4NV7A 1ATKA 4ZUXU 4YYVA 1ITOA 1JQPA 2VFCA 5CVOB 1PPNA 4QH6A 1U9WA 1TU6A 2NQDB 3O1GA 2DZYA 2ARYA 1QOLA 4OELA 1ME3A 1PIPA 2JQFR 1W5RA 3N4CA 1KFUL 2HD5A 1YALA 5K16A 1GX3A 1ME4A 3BCNA 2ATOA 4QRGA 1QXPA 1MHWA 2JQGR 4FK5A 2YJ2A 2R9CA 2GHUA 4RY2A 2H7JA 1CB5A 1AU0A 2NQAA 3KWZA 3H8CA 3MHHA 1CV8A 2DJGB 4PI3A 3OVXA 1MEMA 4W5BA 2P0RA 4KLBA 1POPA 2C0YA 3BPFA 3PNRA 2E00A 4XR7A 1EWOA 2FUDA 3KFQA 4X6JA 1BGOA 1F29A 4MSXA 4AXLA 3V6EA 1AYUA 3B79A 3LXSA 3H89A 3AI8A 3E1ZB 2G7YA 1ICFA 1AYVA 1GECE 2R9NA 1PXVA 1YVBA 1PADA 2G6DA 4I07A 3BPMA 4CDFB 1NLJA 3BOWA 4BS5A 4HWYA 5CHTA 3RVWA 1Y4HA 1QDQA 4N8WA 2AIMA 2E01A 2FRAA 5JA7A 3P5UA 5CVMA 1MDWA 3P5XA 4WA6A 2AS8A 3LTWA 1NL6A 2F7DA 4DMXA 2YJCA 2Y6EA 5JH3A 1STFE 4BQVA 1O0EA 1BP4A 1AIMA 1XKGA 3GCBA 2OZ2A 3NHEA 5EGWA 3PW3A 2VHSA 2DZZA 1YT7A 3CH3X 3TNXA 4P6EA 4Q8HA 4NV8A 2FRQA 3DF0A 2XU3A 4X6IA 2DCCA 1YK7A 2DCAA 1EWPA 1U9VA 1PE6A 1DEUA 3H6SA 3HHAA 2Y5BA 1CJLA 4QBBA 1S4VA 4FIPA 4OEMA 2XU1A 1EWMA 1E2TA 2PADA 4W5CA 2R9FA 2B1NA 2GFOA 3CBKA 1NB5A 2G8EA 3MHSA 3OVZA 3V6CA 1YK8A 3IMAA 3O0UA 3IUTA 1BQIA 2DCDA 6PADA 2NQIA 1CTEA 3D6SA 4YVAA 2P86A 1K3BB 2YJ9A 4YV8A 1KFXL 1GMYA 5FPWA 2YJBA 2WBFX 2E02A 2F1GA 2CB5A 1AYWA 1AU4A 3RVXA 3N3GA 1AU2A 1KHQA 1GCBA 1U5IA 1Y08A 1KHPA 2IPPB 3BWKA 1PCIA 2DC7A 1TLOA 1PPDA 1FH0A 4PP2E 2DC8A 2R9OA 3WXGA 3LFYA 1MS6A 1CVZA 5EF4A 1AU3A 2ACTA 2DCBA 3IV2A 2O6XA 5F02A 2NQGA 4B55A 4CDEB 1SP4B 3K24A 1EWLA 1W6FA 4GUZA 3MTNA 4XUIA 2VHFA 3S3RA 2BSZA 3KW9A 4PP1A 2BDLA 2AVWA 2B1MA 2HHNA 4YYUA 1DF0A 2DC6A 1U9QX 3RVVA 4YYSA 2AYNA 2DC9A 3HD3A 1TL9A 2DJFB 4YYWA 3H7DA 3P5WA 2FTDA 3F5VA 3CH2X 4YYRA 3S3QA 3I06A 2R6NA 1PPOA 5CVNB 4K7CA 8PCHA 3P5VA 4CDDB 3QSDA 3M99A 3ZUAA 3KKUA 1Q6KA 4BSQA 1PBHA 4AXMA 3U8EA 1U9XA 1ZIVA 2CIOA 4P6GA 3HWNA 3IOQA 4Q8GA 1F2AA 1VJVA 3PBHA 4PADA 1GLOA 2VFBA 2AU1A 4FJCA 4BS6A 2YJ8A 1EF7A 1A6RA 1F2BA 2PNSA 3KWBX 3CBJA 1HUCB 4QRVA 2G8JA 3MORA 3KX1A 3QJ3A 3C9EA 3I3TA 4W4UA 1BY8A 2FT2A 3QT4A 2AUXA 3OF8A 3IHPA 1CQDA 4I05A 4BPVA 4N79A 5J94A 1MIRA 2OULA 1CSBB 3IEJA 3K8UA 3D9WA 1QMYA 4I04A 1NB3A 3N3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HH5 A;  3WXF A;  1X9Y A;  1THE A;  9PAP A;  2IBI A;  2E03 A;  3HHI A;  2AYO A;  2P7U A;  5A24 A;  2XU4 A;  4QRX A;  4MZS A;  4DMY A;  1AEC A;  4MZO A;  3WXE A;  2R9M A;  5PAD A;  3OIS A;  4CZW A;  4G54 A;  4X6H A;  1CPJ A;  3K9M A;  2XU5 A;  3BC3 A;  2PBH A;  3F75 A;  4N4Z A;  1NQC A;  3ERV A;  3OF9 A;  2BDZ A;  3USV A;  1CS8 A;  1F2C A;  2AUZ A;  1ZCM A;  4CDC B;  1VSN A;  2HXZ A;  7PCK A;  1SNK A;  1IWD A;  1KXR A;  3PDF A;  3KSE A;  2FO5 A;  2FYE A;  1NPZ A;  2PRE A;  1MEG A;  1PPP A;  1M6D A;  2OP3 A;  3H8B A;  4YYQ A;  5CHV A;  2FQ9 A;  1ATK A;  4ZUX U;  4YYV A;  1ITO A;  1JQP A;  5CVO B;  1PPN A;  4QH6 A;  1U9W A;  1TU6 A;  2NQD B;  3O1G A;  2DZY A;  2ARY A;  1QOL A;  4OEL A;  1ME3 A;  1PIP A;  2JQF R;  3N4C A;  1KFU L;  2HD5 A;  1YAL A;  5K16 A;  1ME4 A;  3BCN A;  2ATO A;  4QRG A;  1QXP A;  1MHW A;  2JQG R;  4FK5 A;  2YJ2 A;  2R9C A;  2GHU A;  4RY2 A;  2H7J A;  1CB5 A;  1AU0 A;  2NQA A;  3KWZ A;  3H8C A;  3MHH A;  1CV8 A;  2DJG B;  4PI3 A;  3OVX A;  1MEM A;  4W5B A;  2P0R A;  4KLB A;  1POP A;  2C0Y A;  3BPF A;  3PNR A;  2E00 A;  4XR7 A;  1EWO A;  2FUD A;  3KFQ A;  4X6J A;  1BGO A;  1F29 A;  4MSX A;  4AXL A;  3V6E A;  1AYU A;  3B79 A;  3LXS A;  3H89 A;  3AI8 A;  3E1Z B;  2G7Y A;  1ICF A;  1AYV A;  1GEC E;  2R9N A;  1PXV A;  1YVB A;  1PAD A;  2G6D A;  4I07 A;  3BPM A;  4CDF B;  1NLJ A;  3BOW A;  4BS5 A;  4HWY A;  5CHT A;  3RVW A;  1Y4H A;  1QDQ A;  4N8W A;  2AIM A;  2E01 A;  2FRA A;  5JA7 A;  3P5U A;  5CVM A;  1MDW A;  3P5X A;  4WA6 A;  2AS8 A;  1NL6 A;  2F7D A;  4DMX A;  2YJC A;  2Y6E A;  5JH3 A;  1STF E;  4BQV A;  1O0E A;  1BP4 A;  1AIM A;  1XKG A;  3GCB A;  2OZ2 A;  3NHE A;  5EGW A;  3PW3 A;  2VHS A;  2DZZ A;  1YT7 A;  3CH3 X;  3TNX A;  4P6E A;  4Q8H A;  2FRQ A;  3DF0 A;  2XU3 A;  4X6I A;  2DCC A;  1YK7 A;  2DCA A;  1EWP A;  1U9V A;  1PE6 A;  1DEU A;  3H6S A;  3HHA A;  2Y5B A;  1CJL A;  4QBB A;  1S4V A;  4FIP A;  4OEM A;  2XU1 A;  1EWM A;  2PAD A;  4W5C A;  2R9F A;  2B1N A;  2GFO A;  3CBK A;  1NB5 A;  2G8E A;  3MHS A;  3OVZ A;  3V6C A;  1YK8 A;  3IMA A;  3O0U A;  3IUT A;  1BQI A;  2DCD A;  6PAD A;  2NQI A;  1CTE A;  3D6S A;  4YVA A;  2P86 A;  1K3B B;  2YJ9 A;  4YV8 A;  1KFX L;  1GMY A;  5FPW A;  2YJB A;  2WBF X;  2E02 A;  2F1G A;  2CB5 A;  1AYW A;  1AU4 A;  3RVX A;  3N3G A;  1AU2 A;  1KHQ A;  1GCB A;  1U5I A;  1Y08 A;  1KHP A;  2IPP B;  3BWK A;  1PCI A;  2DC7 A;  1TLO A;  1PPD A;  1FH0 A;  4PP2 E;  2DC8 A;  2R9O A;  3WXG A;  3LFY A;  1MS6 A;  1CVZ A;  5EF4 A;  1AU3 A;  2ACT A;  2DCB A;  3IV2 A;  2O6X A;  5F02 A;  2NQG A;  4CDE B;  1SP4 B;  3K24 A;  1EWL A;  3MTN A;  4XUI A;  2VHF A;  3S3R A;  3KW9 A;  4PP1 A;  2BDL A;  2AVW A;  2B1M A;  2HHN A;  4YYU A;  1DF0 A;  2DC6 A;  1U9Q X;  3RVV A;  4YYS A;  2AYN A;  2DC9 A;  3HD3 A;  1TL9 A;  2DJF B;  4YYW A;  3H7D A;  3P5W A;  2FTD A;  3F5V A;  3CH2 X;  4YYR A;  3S3Q A;  3I06 A;  2R6N A;  1PPO A;  5CVN B;  4K7C A;  8PCH A;  3P5V A;  4CDD B;  3QSD A;  3M99 A;  3ZUA A;  3KKU A;  1Q6K A;  4BSQ A;  1PBH A;  4AXM A;  3U8E A;  1U9X A;  1ZIV A;  2CIO A;  4P6G A;  3HWN A;  3IOQ A;  4Q8G A;  1F2A A;  1VJV A;  3PBH A;  4PAD A;  1GLO A;  2AU1 A;  4FJC A;  4BS6 A;  2YJ8 A;  1EF7 A;  1A6R A;  1F2B A;  2PNS A;  3KWB X;  3CBJ A;  1HUC B;  4QRV A;  2G8J A;  3MOR A;  3KX1 A;  3QJ3 A;  3C9E A;  3I3T A;  4W4U A;  1BY8 A;  2FT2 A;  3QT4 A;  2AUX A;  3OF8 A;  3IHP A;  1CQD A;  4I05 A;  4BPV A;  4N79 A;  5J94 A;  1MIR A;  2OUL A;  1CSB B;  3IEJ A;  3K8U A;  1QMY A;  4I04 A;  1NB3 A;  3N3K A; 
#chains in the Genus database with same CATH topology
 2HH5 A;  3WXF A;  1X9Y A;  4IP3 A;  4P16 A;  1THE A;  9PAP A;  2IBI A;  1UKF A;  2E03 A;  2JRI A;  3HHI A;  2AYO A;  2P7U A;  5A24 A;  2XU4 A;  4QRX A;  4MZS A;  4DMY A;  1AEC A;  4MZO A;  3WXE A;  2R9M A;  5PAD A;  3TRK A;  3OIS A;  3TMP A;  4CZW A;  4G54 A;  4X6H A;  1CPJ A;  4BOS A;  3K9M A;  2XU5 A;  3BC3 A;  2PBH A;  3F75 A;  4N4Z A;  1NQC A;  3ERV A;  3OF9 A;  2BDZ A;  3USV A;  1CS8 A;  4D8E A;  1F2C A;  2AUZ A;  1ZCM A;  3RNV A;  1VSN A;  4CDC B;  2HXZ A;  7PCK A;  1SNK A;  1IWD A;  4BOZ A;  1KXR A;  3PDF A;  3KSE A;  2FO5 A;  2FYE A;  1NPZ A;  2PRE A;  1MEG A;  1PPP A;  1M6D A;  2OP3 A;  3H8B A;  4YYQ A;  5CHV A;  2FQ9 A;  1ATK A;  4ZUX U;  4YYV A;  1ITO A;  1JQP A;  5CVO B;  5E6J A;  1PPN A;  4QH6 A;  4GUA A;  1U9W A;  1TU6 A;  2NQD B;  3O1G A;  2DZY A;  4IUM A;  2ARY A;  1QOL A;  4OEL A;  1ME3 A;  1PIP A;  2JQF R;  4M0W A;  3N4C A;  1KFU L;  2HD5 A;  3PT2 A;  1YAL A;  5K16 A;  5KO3 A;  1ME4 A;  3BCN A;  2ATO A;  4QRG A;  1QXP A;  1MHW A;  2JQG R;  4FK5 A;  2YJ2 A;  2R9C A;  2GHU A;  4RKX A;  4RY2 A;  2H7J A;  1CB5 A;  3OQC A;  4OVZ A;  1AU0 A;  2NQA A;  4WUR A;  3KWZ A;  3H8C A;  3MHH A;  1CV8 A;  2DJG B;  4RF1 A;  4D8B A;  4PI3 A;  3OVX A;  1MEM A;  4W5B A;  2P0R A;  3BY4 A;  4KLB A;  1POP A;  2C0Y A;  3BPF A;  3PNR A;  2E00 A;  3BB7 A;  4XR7 A;  1EWO A;  2FUD A;  3KFQ A;  3PRM A;  4X6J A;  1BGO A;  1F29 A;  4MSX A;  4AXL A;  3V6E A;  1AYU A;  3B79 A;  3LXS A;  3H89 A;  3AI8 A;  3E1Z B;  4RNA A;  2G7Y A;  1ICF A;  1AYV A;  1GEC E;  2R9N A;  1PXV A;  1YVB A;  1PAD A;  2G6D A;  2UZJ A;  4I07 A;  2AGA A;  3BPM A;  4CDF B;  4ZTB A;  1NLJ A;  3BOW A;  4BS5 A;  4HWY A;  5CHT A;  3IFU A;  3BBA A;  3RVW A;  1Y4H A;  1QDQ A;  2BU3 A;  4N8W A;  2AIM A;  2E01 A;  2FRA A;  5JA7 A;  3P5U A;  4MI7 A;  5CVM A;  1MDW A;  2Z84 A;  3P5X A;  4WA6 A;  2FE8 A;  4XZX A;  2AS8 A;  1NL6 A;  1YZB A;  2F7D A;  4DMX A;  2YJC A;  2Y6E A;  5JH3 A;  1STF E;  4BQV A;  1O0E A;  4OW0 A;  1BP4 A;  1AIM A;  4OVZ B;  1XKG A;  3GCB A;  2OZ2 A;  3NHE A;  3MTV A;  3PW3 A;  5EGW A;  2HWK A;  2DZZ A;  2VHS A;  1YT7 A;  3CH3 X;  3TNX A;  4P6E A;  4Q8H A;  2FRQ A;  3DF0 A;  3C0R A;  2XU3 A;  3PHU A;  1PVJ A;  4X6I A;  2DCC A;  1YK7 A;  2DCA A;  1EWP A;  1U9V A;  1PE6 A;  5JZE A;  1DEU A;  3H6S A;  3PHW A;  2DOS A;  3HHA A;  2Y5B A;  1CJL A;  4QBB A;  1S4V A;  4FIP A;  4OEM A;  2XU1 A;  1EWM A;  2PAD A;  4PT5 A;  4W5C A;  3PHX A;  2R9F A;  2B1N A;  2GFO A;  3CBK A;  1NB5 A;  2J7Q A;  2G8E A;  3MHS A;  3OVZ A;  3V6C A;  1YK8 A;  3IMA A;  3O0U A;  3IUT A;  1BQI A;  2DCD A;  6PAD A;  2NQI A;  4A5U A;  1CTE A;  3W31 A;  3D6S A;  4YVA A;  2P86 A;  1K3B B;  2YJ9 A;  4YV8 A;  1KFX L;  1GMY A;  5FPW A;  2YJB A;  2WBF X;  2E02 A;  3MP2 A;  2F1G A;  2CB5 A;  1AYW A;  1AU4 A;  3RVX A;  3N3G A;  1AU2 A;  1KHQ A;  3O65 A;  1GCB A;  1U5I A;  1Y08 A;  1KHP A;  2IPP B;  3BWK A;  1PCI A;  2DC7 A;  1TLO A;  4D8I A;  1PPD A;  1FH0 A;  4PP2 E;  2DC8 A;  2R9O A;  2BTW B;  3WXG A;  3LFY A;  1MS6 A;  1CVZ A;  4REZ A;  5EF4 A;  1AU3 A;  2ACT A;  2DCB A;  3IV2 A;  2O6X A;  5F02 A;  2NQG A;  3W30 A;  4CDE B;  1SP4 B;  4R3D A;  3K24 A;  1EWL A;  5EZS A;  3ZNH A;  3MTN A;  4XUI A;  2VHF A;  3S3R A;  3KW9 A;  4PP1 A;  4BOQ A;  2BDL A;  2AVW A;  2B1M A;  2HHN A;  4YYU A;  1DF0 A;  2DC6 A;  1U9Q X;  3RVV A;  4YYS A;  2AYN A;  2DC9 A;  3HD3 A;  1TL9 A;  2DJF B;  4YYW A;  3H7D A;  3P5W A;  2FTD A;  3F5V A;  3CH2 X;  2BTW A;  4YYR A;  3S3Q A;  3PRP A;  2JTC A;  3E9S A;  3I06 A;  2R6N A;  1PPO A;  5CVN B;  4K7C A;  8PCH A;  3P5V A;  4CDD B;  3QSD A;  3PSE A;  3M99 A;  3ZUA A;  3KKU A;  1Q6K A;  4BSQ A;  1PBH A;  4AXM A;  3U8E A;  1U9X A;  1ZIV A;  1DKI A;  2CIO A;  4P6G A;  3HWN A;  3IOQ A;  4Q8G A;  1F2A A;  1VJV A;  3PBH A;  4PAD A;  1GLO A;  4MM3 B;  2AU1 A;  4FJC A;  4BS6 A;  5EZQ A;  2YJ8 A;  1EF7 A;  1A6R A;  1F2B A;  2PNS A;  4BOP A;  3KWB X;  3CBJ A;  1HUC B;  4QRV A;  2G8J A;  3MOR A;  3KX1 A;  3QJ3 A;  3C9E A;  3I3T A;  4W4U A;  1BY8 A;  2FT2 A;  3B21 A;  2AUX A;  3QT4 A;  3OF8 A;  4RF0 A;  3IHP A;  1CQD A;  3MJ5 A;  4I05 A;  4BOU A;  4BPV A;  4N79 A;  5J94 A;  1MIR A;  4HXD B;  2OUL A;  1CSB B;  2J7Q C;  3IEJ A;  3K8U A;  1QMY A;  4I04 A;  1NB3 A;  3N3K A; 
#chains in the Genus database with same CATH homology
 2HH5 A;  3WXF A;  1X9Y A;  1THE A;  9PAP A;  2IBI A;  2E03 A;  3HHI A;  2AYO A;  2P7U A;  5A24 A;  2XU4 A;  4QRX A;  4MZS A;  4DMY A;  1AEC A;  4MZO A;  3WXE A;  2R9M A;  5PAD A;  3OIS A;  4CZW A;  4G54 A;  4X6H A;  1CPJ A;  3K9M A;  2XU5 A;  3BC3 A;  2PBH A;  3F75 A;  4N4Z A;  1NQC A;  3ERV A;  3OF9 A;  2BDZ A;  3USV A;  1CS8 A;  1F2C A;  4BGF A;  2AUZ A;  1ZCM A;  4CDC B;  1VSN A;  2HXZ A;  7PCK A;  1SNK A;  1IWD A;  1KXR A;  3PDF A;  3KSE A;  4C5P A;  2FO5 A;  2FYE A;  1NPZ A;  2PRE A;  1MEG A;  1PPP A;  1M6D A;  2OP3 A;  3H8B A;  4YYQ A;  5CHV A;  1W4T A;  2FQ9 A;  4NV7 A;  1ATK A;  4ZUX U;  4YYV A;  1ITO A;  1JQP A;  2VFC A;  5CVO B;  1PPN A;  4QH6 A;  1U9W A;  1TU6 A;  2NQD B;  3O1G A;  2DZY A;  2ARY A;  1QOL A;  4OEL A;  1ME3 A;  1PIP A;  2JQF R;  1W5R A;  3N4C A;  1KFU L;  2HD5 A;  1YAL A;  5K16 A;  1GX3 A;  1ME4 A;  3BCN A;  2ATO A;  4QRG A;  1QXP A;  1MHW A;  2JQG R;  4FK5 A;  2YJ2 A;  2R9C A;  2GHU A;  4RY2 A;  2H7J A;  1CB5 A;  1AU0 A;  2NQA A;  3KWZ A;  3H8C A;  3MHH A;  1CV8 A;  2DJG B;  4PI3 A;  3OVX A;  1MEM A;  4W5B A;  2P0R A;  4KLB A;  1POP A;  2C0Y A;  3BPF A;  3PNR A;  2E00 A;  4XR7 A;  1EWO A;  2FUD A;  3KFQ A;  4X6J A;  1BGO A;  1F29 A;  4MSX A;  4AXL A;  3V6E A;  1AYU A;  3B79 A;  3LXS A;  3H89 A;  3AI8 A;  3E1Z B;  2G7Y A;  1ICF A;  1AYV A;  1GEC E;  2R9N A;  1PXV A;  1YVB A;  1PAD A;  2G6D A;  4I07 A;  3BPM A;  4CDF B;  1NLJ A;  3BOW A;  4BS5 A;  4HWY A;  5CHT A;  3RVW A;  1Y4H A;  1QDQ A;  4N8W A;  2AIM A;  2E01 A;  2FRA A;  5JA7 A;  3P5U A;  5CVM A;  1MDW A;  3P5X A;  4WA6 A;  2AS8 A;  3LTW A;  1NL6 A;  2F7D A;  4DMX A;  2YJC A;  2Y6E A;  5JH3 A;  1STF E;  4BQV A;  1O0E A;  1BP4 A;  1AIM A;  1XKG A;  3GCB A;  2OZ2 A;  3NHE A;  5EGW A;  3PW3 A;  2VHS A;  2DZZ A;  1YT7 A;  3CH3 X;  3TNX A;  4P6E A;  4Q8H A;  4NV8 A;  2FRQ A;  3DF0 A;  2XU3 A;  4X6I A;  2DCC A;  1YK7 A;  2DCA A;  1EWP A;  1U9V A;  1PE6 A;  1DEU A;  3H6S A;  3HHA A;  2Y5B A;  1CJL A;  4QBB A;  1S4V A;  4FIP A;  4OEM A;  2XU1 A;  1EWM A;  1E2T A;  2PAD A;  4W5C A;  2R9F A;  2B1N A;  2GFO A;  3CBK A;  1NB5 A;  2G8E A;  3MHS A;  3OVZ A;  3V6C A;  1YK8 A;  3IMA A;  3O0U A;  3IUT A;  1BQI A;  2DCD A;  6PAD A;  2NQI A;  1CTE A;  3D6S A;  4YVA A;  2P86 A;  1K3B B;  2YJ9 A;  4YV8 A;  1KFX L;  1GMY A;  5FPW A;  2YJB A;  2WBF X;  2E02 A;  2F1G A;  2CB5 A;  1AYW A;  1AU4 A;  3RVX A;  3N3G A;  1AU2 A;  1KHQ A;  1GCB A;  1U5I A;  1Y08 A;  1KHP A;  2IPP B;  3BWK A;  1PCI A;  2DC7 A;  1TLO A;  1PPD A;  1FH0 A;  4PP2 E;  2DC8 A;  2R9O A;  3WXG A;  3LFY A;  1MS6 A;  1CVZ A;  5EF4 A;  1AU3 A;  2ACT A;  2DCB A;  3IV2 A;  2O6X A;  5F02 A;  2NQG A;  4B55 A;  4CDE B;  1SP4 B;  3K24 A;  1EWL A;  1W6F A;  4GUZ A;  3MTN A;  4XUI A;  2VHF A;  3S3R A;  2BSZ A;  3KW9 A;  4PP1 A;  2BDL A;  2AVW A;  2B1M A;  2HHN A;  4YYU A;  1DF0 A;  2DC6 A;  1U9Q X;  3RVV A;  4YYS A;  2AYN A;  2DC9 A;  3HD3 A;  1TL9 A;  2DJF B;  4YYW A;  3H7D A;  3P5W A;  2FTD A;  3F5V A;  3CH2 X;  4YYR A;  3S3Q A;  3I06 A;  2R6N A;  1PPO A;  5CVN B;  4K7C A;  8PCH A;  3P5V A;  4CDD B;  3QSD A;  3M99 A;  3ZUA A;  3KKU A;  1Q6K A;  4BSQ A;  1PBH A;  4AXM A;  3U8E A;  1U9X A;  1ZIV A;  2CIO A;  4P6G A;  3HWN A;  3IOQ A;  4Q8G A;  1F2A A;  1VJV A;  3PBH A;  4PAD A;  1GLO A;  2VFB A;  2AU1 A;  4FJC A;  4BS6 A;  2YJ8 A;  1EF7 A;  1A6R A;  1F2B A;  2PNS A;  3KWB X;  3CBJ A;  1HUC B;  4QRV A;  2G8J A;  3MOR A;  3KX1 A;  3QJ3 A;  3C9E A;  3I3T A;  4W4U A;  1BY8 A;  2FT2 A;  3QT4 A;  2AUX A;  3OF8 A;  3IHP A;  1CQD A;  4I05 A;  4BPV A;  4N79 A;  5J94 A;  1MIR A;  2OUL A;  1CSB B;  3IEJ A;  3K8U A;  3D9W A;  1QMY A;  4I04 A;  1NB3 A;  3N3K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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