1CJLA

Crystal structure of a cysteine protease proform
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
312
structure length
307
Chain Sequence
DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGLQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
pubmed rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROCATHEPSIN L
total genus 60
structure length 307
sequence length 312
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 1996-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1cjlA00
2DJGB 1MEGA 4X6HA 1MHWA 2ARYA 3IMAA 2FT2A 2BDLA 1U9WA 1SP4B 3OF8A 1ZCMA 1EWMA 1YT7A 1PPNA 4PP1A 1ME4A 3KW9A 2JQFR 1MEMA 2OP3A 4I07A 3V6CA 1AECA 1STFE 1AU2A 1PXVA 3K24A 3K8UA 2JQGR 2C0YA 3IUTA 1ATKA 1Y4HA 5CHVA 3P5WA 1AIMA 1CVZA 5EGWA 1GLOA 1DF0A 2E00A 5CVNB 2Y5BA 2R9MA 4N4ZA 2R6NA 2DJFB 3E1ZB 4AXMA 2AUZA 2NQAA 2ACTA 3M99A 3OISA 2PADA 3PNRA 1JQPA 1EWLA 2HHNA 3WXFA 1U9VA 3F5VA 4I04A 1NPZA 3I3TA 1PIPA 2PREA 3P5VA 1MDWA 2YJ9A 4OELA 2DCBA 3LXSA 1CB5A 1YK7A 2XU1A 1PCIA 2PBHA 1ICFA 4MZOA 3OVXA 4BSQA 2H7JA 4G54A 1ZIVA 2DCCA 3IOQA 1CTEA 2R9CA 4PP2E 1F2AA 1PBHA 3S3RA 2NQIA 4QH6A 4PADA 2GFOA 3K9MA 1BQIA 1AU0A 2E01A 3KKUA 4YYQA 1EF7A 2BDZA 3BC3A 5EF4A 1K3BB 4DMYA 4P6GA 3BOWA 5FPWA 3AI8A 4FIPA 4BPVA 4X6IA 1SNKA 1FH0A 2YJBA 1ITOA 2P86A 4HWYA 3CBKA 2F1GA 1POPA 1HUCB 4QRGA 3NHEA 3MHSA 2E03A 3BPFA 2VHSA 4CDDB 4N8WA 2B1MA 3KWZA 4PI3A 2VHFA 1EWPA 2HXZA 1QOLA 2NQGA 3BWKA 4W4UA 3RVXA 2IPPB 3IV2A 1F2BA 2CIOA 2WBFX 3OF9A 1KHQA 3KFQA 4XUIA 4QBBA 5JH3A 2B1NA 1AYVA 1GECE 1AU3A 2FTDA 4I05A 5K16A 3N3KA 4X6JA 4MSXA 4BQVA 2DC8A 4W5CA 2R9NA 1Q6KA 1NLJA 4FJCA 2FUDA 4P6EA 1DEUA 2YJ2A 1IWDA 4YYRA 1YVBA 3BCNA 3H7DA 2E02A 2DZZA 1PE6A 2XU4A 3PBHA 2HH5A 4DMXA 1CJLA 1Y08A 2O6XA 2DC9A 3CBJA 1PADA 1PPDA 4Q8GA 9PAPA 1U9XA 3CH3X 3IEJA 2R9FA 1NB5A 3MHHA 3HWNA 1GMYA 3O0UA 1AYUA 1AU4A 4RY2A 4W5BA 3ZUAA 4BS6A 4YYUA 2AYNA 2FYEA 3P5UA 3C9EA 3V6EA 4XR7A 4YV8A 2IBIA 3HHIA 1ME3A 2XU5A 3IHPA 1MIRA 3O1GA 1KHPA 5PADA 5F02A 4N79A 2NQDB 3KX1A 4KLBA 2OZ2A 1XKGA 1NQCA 1TLOA 3QSDA 1U9QX 1X9YA 1BY8A 1CV8A 2FO5A 2AU1A 2HD5A 1CS8A 1MS6A 1F29A 3WXGA 3H8CA 2FQ9A 3KWBX 1YALA 4QRVA 3RVWA 4CZWA 4CDCB 2Y6EA 2AYOA 1NB3A 4YYWA 6PADA 1BP4A 5CHTA 3USVA 1EWOA 5CVOB 1A6RA 2P0RA 3I06A 3P5XA 1NL6A 1QXPA 3QT4A 1TL9A 3QJ3A 1THEA 1TU6A 2R9OA 4MZSA 3GCBA 3F75A 5J94A 5CVMA 2YJCA 4BS5A 2FRAA 2ATOA 2DC6A 3TNXA 2G8JA 1KXRA 3U8EA 1CSBB 1O0EA 3PDFA 3CH2X 1KFXL 2DC7A 3RVVA 3H8BA 1GCBA 2DZYA 3KSEA 3D6SA 2FRQA 3MORA 3H89A 1KFUL 2OULA 3OVZA 1VJVA 2YJ8A 2DCAA 1PPPA 3DF0A 3MTNA 1M6DA 3LFYA 2GHUA 3PW3A 2XU3A 4WA6A 1PPOA 3N4CA 1BGOA 4AXLA 4YYVA 4ZUXU 2F7DA 3N3GA 2P7UA 4YVAA 4OEMA 4QRXA 1S4VA 3BPMA 2G6DA 4K7CA 1YK8A 3WXEA 2AUXA 2G7YA 7PCKA 4CDEB 4Q8HA 4FK5A 3B79A 2CB5A 1U5IA 1QDQA 2AVWA 4CDFB 2AIMA 1F2CA 1CQDA 3S3QA 8PCHA 1AYWA 3HD3A 5A24A 1VSNA 2AS8A 2DCDA 1CPJA 3HHAA 1QMYA 3ERVA 5JA7A 4YYSA 2PNSA 2G8EA 3H6SA
chains in the Genus database with same CATH superfamily
4RF1A 5E6JA 2DJGB 1MEGA 4X6HA 1MHWA 2ARYA 3IMAA 2FT2A 2BDLA 1U9WA 1SP4B 3OF8A 1ZCMA 1EWMA 1YT7A 1PPNA 4PP1A 1ME4A 3KW9A 2JQFR 1MEMA 2OP3A 3O65A 4I07A 3V6CA 1AECA 1STFE 1AU2A 1PXVA 3K24A 3K8UA 3PSEA 2JQGR 2C0YA 3IUTA 1ATKA 1Y4HA 5CHVA 3P5WA 1AIMA 2BU3A 1CVZA 5EGWA 1GLOA 1DF0A 3BB7A 2E00A 5CVNB 2Y5BA 2R9MA 4N4ZA 2R6NA 2DJFB 3E1ZB 4AXMA 2AUZA 2NQAA 2ACTA 3M99A 3OISA 2PADA 3PNRA 1JQPA 1EWLA 2HHNA 3WXFA 3E9SA 3PHWA 1U9VA 3F5VA 4I04A 1NPZA 3I3TA 1PIPA 2PREA 3P5VA 4REZA 1MDWA 2YJ9A 4OELA 2DCBA 4BOSA 3LXSA 1CB5A 1YK7A 4R3DA 2XU1A 1PCIA 2PBHA 1ICFA 5EZSA 4MZOA 3OVXA 4BSQA 2H7JA 4G54A 1ZIVA 2DCCA 3IOQA 1CTEA 2R9CA 4RKXA 4PP2E 1F2AA 1PBHA 4OW0A 3S3RA 2NQIA 4QH6A 4PADA 2GFOA 3K9MA 1BQIA 2JTCA 1AU0A 2E01A 4ZTBA 3KKUA 4YYQA 4D8BA 1EF7A 2BDZA 3BC3A 2AGAA 5EF4A 1K3BB 4DMYA 5EZQA 4P6GA 3BOWA 5FPWA 3AI8A 4FIPA 4WURA 4BPVA 4X6IA 3PHUA 1SNKA 1FH0A 2YJBA 1ITOA 4XZXA 2P86A 4HWYA 3CBKA 2F1GA 1POPA 1HUCB 4QRGA 3NHEA 3MHSA 2E03A 3BPFA 2VHSA 4CDDB 4N8WA 2B1MA 1YZBA 3KWZA 4PI3A 3C0RA 2VHFA 1EWPA 2HXZA 1QOLA 2NQGA 3BWKA 4W4UA 3RVXA 2IPPB 3IV2A 1F2BA 2CIOA 2DOSA 2WBFX 3BY4A 3OF9A 1KHQA 1DKIA 3KFQA 4XUIA 4GUAA 4RF0A 4QBBA 2J7QA 3PRMA 5JH3A 2B1NA 1AYVA 1GECE 1AU3A 2FTDA 4I05A 5K16A 3N3KA 4X6JA 3MTVA 4MSXA 4BQVA 2DC8A 4W5CA 2R9NA 1Q6KA 4IP3A 1NLJA 4OVZB 4FJCA 2FUDA 4P6EA 4BOPA 1DEUA 2YJ2A 2BTWB 1IWDA 4YYRA 1YVBA 3BCNA 3H7DA 2Z84A 2E02A 2DZZA 1PE6A 2XU4A 4BOUA 3PBHA 4BOZA 2HH5A 4DMXA 1CJLA 1Y08A 2O6XA 2DC9A 3CBJA 4D8IA 1PADA 1PPDA 4Q8GA 9PAPA 1U9XA 4P16A 3CH3X 3IEJA 2R9FA 1NB5A 3ZNHA 3MHHA 3HWNA 1GMYA 3O0UA 1AYUA 1AU4A 4RY2A 4W5BA 3ZUAA 4BS6A 4YYUA 2AYNA 2FYEA 3P5UA 3C9EA 3V6EA 4XR7A 2HWKA 4YV8A 2IBIA 3HHIA 4MI7A 1ME3A 2XU5A 3IHPA 1MIRA 3O1GA 1KHPA 5PADA 4MM3B 5F02A 4N79A 2NQDB 3KX1A 4KLBA 2OZ2A 1XKGA 1NQCA 4PT5A 1TLOA 3QSDA 1U9QX 1X9YA 1BY8A 3PHXA 1CV8A 2FO5A 2AU1A 1UKFA 2HD5A 1CS8A 1MS6A 1F29A 3WXGA 3H8CA 2FQ9A 3KWBX 1YALA 4QRVA 3RVWA 4CZWA 4CDCB 2Y6EA 2AYOA 1NB3A 4YYWA 6PADA 1BP4A 5CHTA 3USVA 1EWOA 5CVOB 1A6RA 2P0RA 4A5UA 3MJ5A 3I06A 2FE8A 3P5XA 1NL6A 1PVJA 1QXPA 3QT4A 4D8EA 1TL9A 2JRIA 3QJ3A 5JZEA 1THEA 1TU6A 2R9OA 4MZSA 3GCBA 3F75A 5J94A 3B21A 5CVMA 2YJCA 4BS5A 2FRAA 3IFUA 3W30A 2ATOA 2DC6A 2J7QC 3TNXA 2G8JA 1KXRA 3MP2A 1CSBB 1O0EA 3U8EA 3PDFA 3CH2X 1KFXL 3BBAA 4OVZA 2DC7A 4HXDB 3RVVA 3H8BA 1GCBA 2BTWA 2UZJA 2DZYA 3KSEA 3D6SA 2FRQA 3MORA 3H89A 3TRKA 1KFUL 2OULA 3OVZA 3W31A 4BOQA 3RNVA 1VJVA 3PRPA 2YJ8A 2DCAA 4RNAA 1PPPA 3DF0A 3MTNA 3TMPA 1M6DA 3LFYA 2GHUA 3PW3A 2XU3A 4WA6A 1PPOA 3N4CA 1BGOA 4AXLA 4YYVA 4ZUXU 2F7DA 3N3GA 2P7UA 4YVAA 4OEMA 4QRXA 1S4VA 5KO3A 3BPMA 2G6DA 4K7CA 1YK8A 3WXEA 2AUXA 2G7YA 7PCKA 3PT2A 4CDEB 4Q8HA 4FK5A 3B79A 2CB5A 1U5IA 1QDQA 2AVWA 4CDFB 2AIMA 1F2CA 1CQDA 3S3QA 8PCHA 1AYWA 3HD3A 4M0WA 5A24A 1VSNA 2AS8A 2DCDA 1CPJA 4IUMA 3HHAA 3OQCA 1QMYA 3ERVA 5JA7A 4YYSA 2PNSA 2G8EA 3H6SA
chains in the Genus database with same CATH topology
1E2TA 2DJGB 1MEGA 3D9WA 4X6HA 1MHWA 2ARYA 3IMAA 2FT2A 2BDLA 1U9WA 1SP4B 3OF8A 4C5PA 1ZCMA 1EWMA 1YT7A 1PPNA 4PP1A 1ME4A 3KW9A 2JQFR 1MEMA 2OP3A 4I07A 3V6CA 1AECA 1STFE 1AU2A 1PXVA 3K24A 3K8UA 2JQGR 2C0YA 3IUTA 1ATKA 1Y4HA 5CHVA 3P5WA 1AIMA 1CVZA 5EGWA 1GLOA 1DF0A 2E00A 5CVNB 1W4TA 2Y5BA 2R9MA 4N4ZA 2R6NA 2DJFB 3E1ZB 4AXMA 2AUZA 2NQAA 2ACTA 3M99A 3OISA 2PADA 3PNRA 1JQPA 1EWLA 2HHNA 3WXFA 1U9VA 3F5VA 4I04A 1NPZA 3I3TA 1PIPA 2PREA 3P5VA 1MDWA 2YJ9A 4OELA 2DCBA 3LXSA 1CB5A 1YK7A 2VFCA 2XU1A 1PCIA 2PBHA 1ICFA 4MZOA 3OVXA 4BSQA 2H7JA 4G54A 1ZIVA 2DCCA 3IOQA 1CTEA 2R9CA 4PP2E 1F2AA 1PBHA 3S3RA 2NQIA 4QH6A 4PADA 2GFOA 3K9MA 1BQIA 1AU0A 2E01A 3KKUA 4YYQA 1W6FA 1EF7A 2BDZA 3BC3A 5EF4A 1K3BB 4DMYA 4P6GA 3BOWA 5FPWA 3AI8A 4FIPA 4BPVA 4X6IA 1SNKA 1FH0A 2YJBA 1ITOA 4B55A 2P86A 4HWYA 3CBKA 2F1GA 1POPA 1HUCB 4QRGA 3NHEA 3MHSA 2E03A 3BPFA 2VHSA 4CDDB 4N8WA 2B1MA 3KWZA 4PI3A 2VHFA 1EWPA 2HXZA 4NV7A 1QOLA 2NQGA 3BWKA 4W4UA 3RVXA 2IPPB 3IV2A 1F2BA 2CIOA 2WBFX 3OF9A 1KHQA 3KFQA 4BGFA 4XUIA 4QBBA 5JH3A 2B1NA 1AYVA 1GECE 1AU3A 2FTDA 4I05A 5K16A 2VFBA 3N3KA 4X6JA 4MSXA 4BQVA 2DC8A 4W5CA 2R9NA 1Q6KA 1NLJA 3LTWA 4FJCA 2FUDA 4P6EA 1DEUA 2YJ2A 1IWDA 4YYRA 1YVBA 3BCNA 3H7DA 2E02A 2DZZA 1PE6A 2XU4A 3PBHA 2HH5A 4DMXA 1CJLA 1Y08A 2O6XA 2DC9A 3CBJA 1PADA 1PPDA 4Q8GA 9PAPA 1U9XA 3CH3X 3IEJA 2R9FA 1NB5A 3MHHA 3HWNA 1GMYA 3O0UA 1AYUA 1AU4A 4RY2A 4W5BA 3ZUAA 4BS6A 4YYUA 2AYNA 2FYEA 3P5UA 3C9EA 3V6EA 4XR7A 4YV8A 2IBIA 3HHIA 1ME3A 2XU5A 3IHPA 1MIRA 3O1GA 1KHPA 5PADA 5F02A 4N79A 2NQDB 1W5RA 3KX1A 4KLBA 2OZ2A 1XKGA 1NQCA 1TLOA 3QSDA 1U9QX 1X9YA 1BY8A 1CV8A 2FO5A 2AU1A 2HD5A 1CS8A 1MS6A 1F29A 3WXGA 3H8CA 2FQ9A 3KWBX 1YALA 4QRVA 3RVWA 4CZWA 4CDCB 2Y6EA 2AYOA 1NB3A 4GUZA 4YYWA 6PADA 1BP4A 5CHTA 3USVA 1EWOA 5CVOB 1GX3A 1A6RA 2P0RA 3I06A 3P5XA 1NL6A 1QXPA 3QT4A 1TL9A 3QJ3A 1THEA 1TU6A 2R9OA 4MZSA 3GCBA 3F75A 5J94A 5CVMA 2YJCA 4BS5A 2FRAA 2ATOA 2DC6A 3TNXA 2G8JA 1KXRA 3U8EA 1CSBB 1O0EA 3PDFA 3CH2X 1KFXL 2DC7A 3RVVA 3H8BA 1GCBA 2DZYA 3KSEA 3D6SA 2FRQA 3MORA 3H89A 1KFUL 2OULA 3OVZA 1VJVA 2YJ8A 2DCAA 1PPPA 3DF0A 3MTNA 1M6DA 3LFYA 2GHUA 3PW3A 2XU3A 4WA6A 1PPOA 3N4CA 1BGOA 4AXLA 4YYVA 4ZUXU 2F7DA 3N3GA 2P7UA 4YVAA 4OEMA 4QRXA 1S4VA 3BPMA 2G6DA 4K7CA 1YK8A 3WXEA 2AUXA 2G7YA 7PCKA 4CDEB 4Q8HA 4NV8A 4FK5A 3B79A 2CB5A 1U5IA 1QDQA 2AVWA 4CDFB 2AIMA 1F2CA 1CQDA 3S3QA 8PCHA 1AYWA 3HD3A 5A24A 1VSNA 2AS8A 2DCDA 1CPJA 3HHAA 1QMYA 3ERVA 5JA7A 4YYSA 2PNSA 2BSZA 2G8EA 3H6SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DJG B;  1MEG A;  4X6H A;  1MHW A;  2ARY A;  3IMA A;  2FT2 A;  2BDL A;  1U9W A;  1SP4 B;  3OF8 A;  1ZCM A;  1EWM A;  1YT7 A;  1PPN A;  4PP1 A;  1ME4 A;  3KW9 A;  2JQF R;  1MEM A;  2OP3 A;  4I07 A;  3V6C A;  1AEC A;  1STF E;  1AU2 A;  1PXV A;  3K24 A;  3K8U A;  2JQG R;  2C0Y A;  3IUT A;  1ATK A;  1Y4H A;  5CHV A;  3P5W A;  1AIM A;  1CVZ A;  5EGW A;  1GLO A;  1DF0 A;  2E00 A;  5CVN B;  2Y5B A;  2R9M A;  4N4Z A;  2R6N A;  2DJF B;  3E1Z B;  4AXM A;  2AUZ A;  2NQA A;  2ACT A;  3M99 A;  3OIS A;  2PAD A;  3PNR A;  1JQP A;  1EWL A;  2HHN A;  3WXF A;  1U9V A;  3F5V A;  4I04 A;  1NPZ A;  3I3T A;  1PIP A;  2PRE A;  3P5V A;  1MDW A;  2YJ9 A;  4OEL A;  2DCB A;  3LXS A;  1CB5 A;  1YK7 A;  2XU1 A;  1PCI A;  2PBH A;  1ICF A;  4MZO A;  3OVX A;  4BSQ A;  2H7J A;  4G54 A;  1ZIV A;  2DCC A;  3IOQ A;  1CTE A;  2R9C A;  4PP2 E;  1F2A A;  1PBH A;  3S3R A;  2NQI A;  4QH6 A;  4PAD A;  2GFO A;  3K9M A;  1BQI A;  1AU0 A;  2E01 A;  3KKU A;  4YYQ A;  1EF7 A;  2BDZ A;  3BC3 A;  5EF4 A;  1K3B B;  4DMY A;  4P6G A;  3BOW A;  5FPW A;  3AI8 A;  4FIP A;  4BPV A;  4X6I A;  1SNK A;  1FH0 A;  2YJB A;  1ITO A;  2P86 A;  4HWY A;  3CBK A;  2F1G A;  1POP A;  1HUC B;  4QRG A;  3NHE A;  3MHS A;  2E03 A;  3BPF A;  2VHS A;  4CDD B;  4N8W A;  2B1M A;  3KWZ A;  4PI3 A;  2VHF A;  1EWP A;  2HXZ A;  1QOL A;  2NQG A;  3BWK A;  4W4U A;  3RVX A;  2IPP B;  3IV2 A;  1F2B A;  2CIO A;  2WBF X;  3OF9 A;  1KHQ A;  3KFQ A;  4XUI A;  4QBB A;  5JH3 A;  2B1N A;  1AYV A;  1GEC E;  1AU3 A;  2FTD A;  4I05 A;  5K16 A;  3N3K A;  4X6J A;  4MSX A;  4BQV A;  2DC8 A;  4W5C A;  2R9N A;  1Q6K A;  1NLJ A;  4FJC A;  2FUD A;  4P6E A;  1DEU A;  2YJ2 A;  1IWD A;  4YYR A;  1YVB A;  3BCN A;  3H7D A;  2E02 A;  2DZZ A;  1PE6 A;  2XU4 A;  3PBH A;  2HH5 A;  4DMX A;  1CJL A;  1Y08 A;  2O6X A;  2DC9 A;  3CBJ A;  1PAD A;  1PPD A;  4Q8G A;  9PAP A;  1U9X A;  3CH3 X;  3IEJ A;  2R9F A;  1NB5 A;  3MHH A;  3HWN A;  1GMY A;  3O0U A;  1AYU A;  1AU4 A;  4RY2 A;  4W5B A;  3ZUA A;  4BS6 A;  4YYU A;  2AYN A;  2FYE A;  3P5U A;  3C9E A;  3V6E A;  4XR7 A;  4YV8 A;  2IBI A;  3HHI A;  1ME3 A;  2XU5 A;  3IHP A;  1MIR A;  3O1G A;  1KHP A;  5PAD A;  5F02 A;  4N79 A;  2NQD B;  3KX1 A;  4KLB A;  2OZ2 A;  1XKG A;  1NQC A;  1TLO A;  3QSD A;  1U9Q X;  1X9Y A;  1BY8 A;  1CV8 A;  2FO5 A;  2AU1 A;  2HD5 A;  1CS8 A;  1MS6 A;  1F29 A;  3WXG A;  3H8C A;  2FQ9 A;  3KWB X;  1YAL A;  4QRV A;  3RVW A;  4CZW A;  4CDC B;  2Y6E A;  2AYO A;  1NB3 A;  4YYW A;  6PAD A;  1BP4 A;  5CHT A;  3USV A;  1EWO A;  5CVO B;  1A6R A;  2P0R A;  3I06 A;  3P5X A;  1NL6 A;  1QXP A;  3QT4 A;  1TL9 A;  3QJ3 A;  1THE A;  1TU6 A;  2R9O A;  4MZS A;  3GCB A;  3F75 A;  5J94 A;  5CVM A;  2YJC A;  4BS5 A;  2FRA A;  2ATO A;  2DC6 A;  3TNX A;  2G8J A;  1KXR A;  3U8E A;  1CSB B;  1O0E A;  3PDF A;  3CH2 X;  1KFX L;  2DC7 A;  3RVV A;  3H8B A;  1GCB A;  2DZY A;  3KSE A;  3D6S A;  2FRQ A;  3MOR A;  3H89 A;  1KFU L;  2OUL A;  3OVZ A;  1VJV A;  2YJ8 A;  2DCA A;  1PPP A;  3DF0 A;  3MTN A;  1M6D A;  3LFY A;  2GHU A;  3PW3 A;  2XU3 A;  4WA6 A;  1PPO A;  3N4C A;  1BGO A;  4AXL A;  4YYV A;  4ZUX U;  2F7D A;  3N3G A;  2P7U A;  4YVA A;  4OEM A;  4QRX A;  1S4V A;  3BPM A;  2G6D A;  4K7C A;  1YK8 A;  3WXE A;  2AUX A;  2G7Y A;  7PCK A;  4CDE B;  4Q8H A;  4FK5 A;  3B79 A;  2CB5 A;  1U5I A;  1QDQ A;  2AVW A;  4CDF B;  2AIM A;  1F2C A;  1CQD A;  3S3Q A;  8PCH A;  1AYW A;  3HD3 A;  5A24 A;  1VSN A;  2AS8 A;  2DCD A;  1CPJ A;  3HHA A;  1QMY A;  3ERV A;  5JA7 A;  4YYS A;  2PNS A;  2G8E A;  3H6S A; 
#chains in the Genus database with same CATH topology
 4RF1 A;  5E6J A;  2DJG B;  1MEG A;  4X6H A;  1MHW A;  2ARY A;  3IMA A;  2FT2 A;  2BDL A;  1U9W A;  1SP4 B;  3OF8 A;  1ZCM A;  1EWM A;  1YT7 A;  1PPN A;  4PP1 A;  1ME4 A;  3KW9 A;  2JQF R;  1MEM A;  2OP3 A;  3O65 A;  4I07 A;  3V6C A;  1AEC A;  1STF E;  1AU2 A;  1PXV A;  3K24 A;  3K8U A;  3PSE A;  2JQG R;  2C0Y A;  3IUT A;  1ATK A;  1Y4H A;  5CHV A;  3P5W A;  1AIM A;  2BU3 A;  1CVZ A;  5EGW A;  1GLO A;  1DF0 A;  3BB7 A;  2E00 A;  5CVN B;  2Y5B A;  2R9M A;  4N4Z A;  2R6N A;  2DJF B;  3E1Z B;  4AXM A;  2AUZ A;  2NQA A;  2ACT A;  3M99 A;  3OIS A;  2PAD A;  3PNR A;  1JQP A;  1EWL A;  2HHN A;  3WXF A;  3E9S A;  3PHW A;  1U9V A;  3F5V A;  4I04 A;  1NPZ A;  3I3T A;  1PIP A;  2PRE A;  3P5V A;  4REZ A;  1MDW A;  2YJ9 A;  4OEL A;  2DCB A;  4BOS A;  3LXS A;  1CB5 A;  1YK7 A;  4R3D A;  2XU1 A;  1PCI A;  2PBH A;  1ICF A;  5EZS A;  4MZO A;  3OVX A;  4BSQ A;  2H7J A;  4G54 A;  1ZIV A;  2DCC A;  3IOQ A;  1CTE A;  2R9C A;  4RKX A;  4PP2 E;  1F2A A;  1PBH A;  4OW0 A;  3S3R A;  2NQI A;  4QH6 A;  4PAD A;  2GFO A;  3K9M A;  1BQI A;  2JTC A;  1AU0 A;  2E01 A;  4ZTB A;  3KKU A;  4YYQ A;  4D8B A;  1EF7 A;  2BDZ A;  3BC3 A;  2AGA A;  5EF4 A;  1K3B B;  4DMY A;  5EZQ A;  4P6G A;  3BOW A;  5FPW A;  3AI8 A;  4FIP A;  4WUR A;  4BPV A;  4X6I A;  3PHU A;  1SNK A;  1FH0 A;  2YJB A;  1ITO A;  4XZX A;  2P86 A;  4HWY A;  3CBK A;  2F1G A;  1POP A;  1HUC B;  4QRG A;  3NHE A;  3MHS A;  2E03 A;  3BPF A;  2VHS A;  4CDD B;  4N8W A;  2B1M A;  1YZB A;  3KWZ A;  4PI3 A;  3C0R A;  2VHF A;  1EWP A;  2HXZ A;  1QOL A;  2NQG A;  3BWK A;  4W4U A;  3RVX A;  2IPP B;  3IV2 A;  1F2B A;  2CIO A;  2DOS A;  2WBF X;  3BY4 A;  3OF9 A;  1KHQ A;  1DKI A;  3KFQ A;  4XUI A;  4GUA A;  4RF0 A;  4QBB A;  2J7Q A;  3PRM A;  5JH3 A;  2B1N A;  1AYV A;  1GEC E;  1AU3 A;  2FTD A;  4I05 A;  5K16 A;  3N3K A;  4X6J A;  3MTV A;  4MSX A;  4BQV A;  2DC8 A;  4W5C A;  2R9N A;  1Q6K A;  4IP3 A;  1NLJ A;  4OVZ B;  4FJC A;  2FUD A;  4P6E A;  4BOP A;  1DEU A;  2YJ2 A;  2BTW B;  1IWD A;  4YYR A;  1YVB A;  3BCN A;  3H7D A;  2Z84 A;  2E02 A;  2DZZ A;  1PE6 A;  2XU4 A;  4BOU A;  3PBH A;  4BOZ A;  2HH5 A;  4DMX A;  1CJL A;  1Y08 A;  2O6X A;  2DC9 A;  3CBJ A;  4D8I A;  1PAD A;  1PPD A;  4Q8G A;  9PAP A;  1U9X A;  4P16 A;  3CH3 X;  3IEJ A;  2R9F A;  1NB5 A;  3ZNH A;  3MHH A;  3HWN A;  1GMY A;  3O0U A;  1AYU A;  1AU4 A;  4RY2 A;  4W5B A;  3ZUA A;  4BS6 A;  4YYU A;  2AYN A;  2FYE A;  3P5U A;  3C9E A;  3V6E A;  4XR7 A;  2HWK A;  4YV8 A;  2IBI A;  3HHI A;  4MI7 A;  1ME3 A;  2XU5 A;  3IHP A;  1MIR A;  3O1G A;  1KHP A;  5PAD A;  4MM3 B;  5F02 A;  4N79 A;  2NQD B;  3KX1 A;  4KLB A;  2OZ2 A;  1XKG A;  1NQC A;  4PT5 A;  1TLO A;  3QSD A;  1U9Q X;  1X9Y A;  1BY8 A;  3PHX A;  1CV8 A;  2FO5 A;  2AU1 A;  1UKF A;  2HD5 A;  1CS8 A;  1MS6 A;  1F29 A;  3WXG A;  3H8C A;  2FQ9 A;  3KWB X;  1YAL A;  4QRV A;  3RVW A;  4CZW A;  4CDC B;  2Y6E A;  2AYO A;  1NB3 A;  4YYW A;  6PAD A;  1BP4 A;  5CHT A;  3USV A;  1EWO A;  5CVO B;  1A6R A;  2P0R A;  4A5U A;  3MJ5 A;  3I06 A;  2FE8 A;  3P5X A;  1NL6 A;  1PVJ A;  1QXP A;  3QT4 A;  4D8E A;  1TL9 A;  2JRI A;  3QJ3 A;  5JZE A;  1THE A;  1TU6 A;  2R9O A;  4MZS A;  3GCB A;  3F75 A;  5J94 A;  3B21 A;  5CVM A;  2YJC A;  4BS5 A;  2FRA A;  3IFU A;  3W30 A;  2ATO A;  2DC6 A;  2J7Q C;  3TNX A;  2G8J A;  1KXR A;  3MP2 A;  1CSB B;  1O0E A;  3U8E A;  3PDF A;  3CH2 X;  1KFX L;  3BBA A;  4OVZ A;  2DC7 A;  4HXD B;  3RVV A;  3H8B A;  1GCB A;  2BTW A;  2UZJ A;  2DZY A;  3KSE A;  3D6S A;  2FRQ A;  3MOR A;  3H89 A;  3TRK A;  1KFU L;  2OUL A;  3OVZ A;  3W31 A;  4BOQ A;  3RNV A;  1VJV A;  3PRP A;  2YJ8 A;  2DCA A;  4RNA A;  1PPP A;  3DF0 A;  3MTN A;  3TMP A;  1M6D A;  3LFY A;  2GHU A;  3PW3 A;  2XU3 A;  4WA6 A;  1PPO A;  3N4C A;  1BGO A;  4AXL A;  4YYV A;  4ZUX U;  2F7D A;  3N3G A;  2P7U A;  4YVA A;  4OEM A;  4QRX A;  1S4V A;  5KO3 A;  3BPM A;  2G6D A;  4K7C A;  1YK8 A;  3WXE A;  2AUX A;  2G7Y A;  7PCK A;  3PT2 A;  4CDE B;  4Q8H A;  4FK5 A;  3B79 A;  2CB5 A;  1U5I A;  1QDQ A;  2AVW A;  4CDF B;  2AIM A;  1F2C A;  1CQD A;  3S3Q A;  8PCH A;  1AYW A;  3HD3 A;  4M0W A;  5A24 A;  1VSN A;  2AS8 A;  2DCD A;  1CPJ A;  4IUM A;  3HHA A;  3OQC A;  1QMY A;  3ERV A;  5JA7 A;  4YYS A;  2PNS A;  2G8E A;  3H6S A; 
#chains in the Genus database with same CATH homology
 1E2T A;  2DJG B;  1MEG A;  3D9W A;  4X6H A;  1MHW A;  2ARY A;  3IMA A;  2FT2 A;  2BDL A;  1U9W A;  1SP4 B;  3OF8 A;  4C5P A;  1ZCM A;  1EWM A;  1YT7 A;  1PPN A;  4PP1 A;  1ME4 A;  3KW9 A;  2JQF R;  1MEM A;  2OP3 A;  4I07 A;  3V6C A;  1AEC A;  1STF E;  1AU2 A;  1PXV A;  3K24 A;  3K8U A;  2JQG R;  2C0Y A;  3IUT A;  1ATK A;  1Y4H A;  5CHV A;  3P5W A;  1AIM A;  1CVZ A;  5EGW A;  1GLO A;  1DF0 A;  2E00 A;  5CVN B;  1W4T A;  2Y5B A;  2R9M A;  4N4Z A;  2R6N A;  2DJF B;  3E1Z B;  4AXM A;  2AUZ A;  2NQA A;  2ACT A;  3M99 A;  3OIS A;  2PAD A;  3PNR A;  1JQP A;  1EWL A;  2HHN A;  3WXF A;  1U9V A;  3F5V A;  4I04 A;  1NPZ A;  3I3T A;  1PIP A;  2PRE A;  3P5V A;  1MDW A;  2YJ9 A;  4OEL A;  2DCB A;  3LXS A;  1CB5 A;  1YK7 A;  2VFC A;  2XU1 A;  1PCI A;  2PBH A;  1ICF A;  4MZO A;  3OVX A;  4BSQ A;  2H7J A;  4G54 A;  1ZIV A;  2DCC A;  3IOQ A;  1CTE A;  2R9C A;  4PP2 E;  1F2A A;  1PBH A;  3S3R A;  2NQI A;  4QH6 A;  4PAD A;  2GFO A;  3K9M A;  1BQI A;  1AU0 A;  2E01 A;  3KKU A;  4YYQ A;  1W6F A;  1EF7 A;  2BDZ A;  3BC3 A;  5EF4 A;  1K3B B;  4DMY A;  4P6G A;  3BOW A;  5FPW A;  3AI8 A;  4FIP A;  4BPV A;  4X6I A;  1SNK A;  1FH0 A;  2YJB A;  1ITO A;  4B55 A;  2P86 A;  4HWY A;  3CBK A;  2F1G A;  1POP A;  1HUC B;  4QRG A;  3NHE A;  3MHS A;  2E03 A;  3BPF A;  2VHS A;  4CDD B;  4N8W A;  2B1M A;  3KWZ A;  4PI3 A;  2VHF A;  1EWP A;  2HXZ A;  4NV7 A;  1QOL A;  2NQG A;  3BWK A;  4W4U A;  3RVX A;  2IPP B;  3IV2 A;  1F2B A;  2CIO A;  2WBF X;  3OF9 A;  1KHQ A;  3KFQ A;  4BGF A;  4XUI A;  4QBB A;  5JH3 A;  2B1N A;  1AYV A;  1GEC E;  1AU3 A;  2FTD A;  4I05 A;  5K16 A;  2VFB A;  3N3K A;  4X6J A;  4MSX A;  4BQV A;  2DC8 A;  4W5C A;  2R9N A;  1Q6K A;  1NLJ A;  3LTW A;  4FJC A;  2FUD A;  4P6E A;  1DEU A;  2YJ2 A;  1IWD A;  4YYR A;  1YVB A;  3BCN A;  3H7D A;  2E02 A;  2DZZ A;  1PE6 A;  2XU4 A;  3PBH A;  2HH5 A;  4DMX A;  1CJL A;  1Y08 A;  2O6X A;  2DC9 A;  3CBJ A;  1PAD A;  1PPD A;  4Q8G A;  9PAP A;  1U9X A;  3CH3 X;  3IEJ A;  2R9F A;  1NB5 A;  3MHH A;  3HWN A;  1GMY A;  3O0U A;  1AYU A;  1AU4 A;  4RY2 A;  4W5B A;  3ZUA A;  4BS6 A;  4YYU A;  2AYN A;  2FYE A;  3P5U A;  3C9E A;  3V6E A;  4XR7 A;  4YV8 A;  2IBI A;  3HHI A;  1ME3 A;  2XU5 A;  3IHP A;  1MIR A;  3O1G A;  1KHP A;  5PAD A;  5F02 A;  4N79 A;  2NQD B;  1W5R A;  3KX1 A;  4KLB A;  2OZ2 A;  1XKG A;  1NQC A;  1TLO A;  3QSD A;  1U9Q X;  1X9Y A;  1BY8 A;  1CV8 A;  2FO5 A;  2AU1 A;  2HD5 A;  1CS8 A;  1MS6 A;  1F29 A;  3WXG A;  3H8C A;  2FQ9 A;  3KWB X;  1YAL A;  4QRV A;  3RVW A;  4CZW A;  4CDC B;  2Y6E A;  2AYO A;  1NB3 A;  4GUZ A;  4YYW A;  6PAD A;  1BP4 A;  5CHT A;  3USV A;  1EWO A;  5CVO B;  1GX3 A;  1A6R A;  2P0R A;  3I06 A;  3P5X A;  1NL6 A;  1QXP A;  3QT4 A;  1TL9 A;  3QJ3 A;  1THE A;  1TU6 A;  2R9O A;  4MZS A;  3GCB A;  3F75 A;  5J94 A;  5CVM A;  2YJC A;  4BS5 A;  2FRA A;  2ATO A;  2DC6 A;  3TNX A;  2G8J A;  1KXR A;  3U8E A;  1CSB B;  1O0E A;  3PDF A;  3CH2 X;  1KFX L;  2DC7 A;  3RVV A;  3H8B A;  1GCB A;  2DZY A;  3KSE A;  3D6S A;  2FRQ A;  3MOR A;  3H89 A;  1KFU L;  2OUL A;  3OVZ A;  1VJV A;  2YJ8 A;  2DCA A;  1PPP A;  3DF0 A;  3MTN A;  1M6D A;  3LFY A;  2GHU A;  3PW3 A;  2XU3 A;  4WA6 A;  1PPO A;  3N4C A;  1BGO A;  4AXL A;  4YYV A;  4ZUX U;  2F7D A;  3N3G A;  2P7U A;  4YVA A;  4OEM A;  4QRX A;  1S4V A;  3BPM A;  2G6D A;  4K7C A;  1YK8 A;  3WXE A;  2AUX A;  2G7Y A;  7PCK A;  4CDE B;  4Q8H A;  4NV8 A;  4FK5 A;  3B79 A;  2CB5 A;  1U5I A;  1QDQ A;  2AVW A;  4CDF B;  2AIM A;  1F2C A;  1CQD A;  3S3Q A;  8PCH A;  1AYW A;  3HD3 A;  5A24 A;  1VSN A;  2AS8 A;  2DCD A;  1CPJ A;  3HHA A;  1QMY A;  3ERV A;  5JA7 A;  4YYS A;  2PNS A;  2BSZ A;  2G8E A;  3H6S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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