1EWPA

Cruzain bound to mor-leu-hpq
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
215
structure length
215
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Trypanosoma cruzi
publication title Chapter 3: X-ray Structures of Complexes of Cruzain with Designed Covalent Inhibitors
pubmed rcsb
molecule keywords CRUZAIN
total genus 67
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2000-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1ewpA00
4BQVA 3IMAA 1AU3A 3MHHA 1ME3A 1XKGA 2HD5A 2XU4A 2OP3A 3WXEA 4YYRA 1HUCB 1YT7A 3MORA 4FJCA 4QRVA 3PDFA 4CDCB 3BPFA 4BS6A 1AYWA 2FQ9A 1SNKA 5A24A 3CBKA 1BQIA 3LFYA 1KFXL 1Y4HA 4N8WA 4KLBA 4PP1A 1K3BB 1PADA 3RVWA 1AECA 2B1MA 2DCDA 1PPNA 3HWNA 1CJLA 1Q6KA 2R9FA 4AXMA 2NQDB 1YALA 1A6RA 1MEMA 2HH5A 3BCNA 1EWOA 4BSQA 3N4CA 4I04A 3D6SA 4QRGA 1PIPA 1ATKA 2AUXA 3F75A 3P5XA 2YJ8A 2FO5A 3HHAA 3QT4A 3BPMA 2O6XA 4AXLA 2DC7A 1PE6A 3IV2A 4HWYA 3KWZA 1QMYA 4PI3A 2F7DA 4P6GA 4X6HA 2NQAA 2P86A 3KW9A 2AYOA 3TNXA 3USVA 2FT2A 2NQGA 2OZ2A 3GCBA 1MS6A 1ME4A 1AU0A 3H89A 2YJCA 1YVBA 1PBHA 2PREA 5CVNB 4I07A 5EGWA 2E01A 3RVVA 1THEA 3K8UA 3RVXA 2VHSA 1AYUA 4CDDB 3NHEA 5JH3A 9PAPA 3S3RA 1YK7A 2P7UA 3OF9A 2G8JA 2F1GA 2R9NA 1GCBA 2YJBA 2IBIA 1PPPA 3IEJA 3WXGA 1U5IA 2DCCA 3BWKA 1TL9A 3HHIA 1AU4A 3PNRA 1YK8A 3KKUA 1MDWA 5EF4A 3U8EA 3IHPA 2YJ9A 3AI8A 3H8BA 7PCKA 2CIOA 3PW3A 3O0UA 2VHFA 5CVOB 4YYSA 3MTNA 3N3KA 2HHNA 2ATOA 4MSXA 1GECE 4K7CA 1F29A 2AUZA 1U9VA 3QJ3A 2IPPB 2E03A 2C0YA 1JQPA 1Y08A 2R9MA 4YYQA 2R6NA 3IUTA 4FIPA 3H7DA 2B1NA 3QSDA 1S4VA 2DZYA 3CBJA 1KHQA 1M6DA 2R9OA 3K9MA 1ICFA 3I3TA 1MEGA 1PXVA 2AYNA 5CHTA 1DF0A 3WXFA 4YYUA 5J94A 1PCIA 2DCAA 4XUIA 6PADA 4G54A 4OELA 3HD3A 2JQGR 1CSBB 3KSEA 4MZSA 4Q8HA 3BOWA 3K24A 4QH6A 2XU1A 4CDEB 3M99A 2BDZA 4BS5A 3C9EA 4DMYA 3F5VA 2G6DA 4XR7A 4OEMA 3DF0A 2WBFX 5CHVA 1CTEA 1QXPA 1TLOA 1IWDA 4W5BA 3OF8A 4QRXA 1NLJA 4P6EA 1KXRA 4N79A 4QBBA 1NB5A 1ZCMA 1SP4B 2Y6EA 2FTDA 3V6EA 2G7YA 1CB5A 2DC8A 2CB5A 1NL6A 3KFQA 1QDQA 4RY2A 2FRQA 2PADA 1CVZA 5JA7A 1BP4A 4PADA 2OULA 3IOQA 2DJFB 1NQCA 1VJVA 2FUDA 3S3QA 3OVXA 2P0RA 3LXSA 2GFOA 2FRAA 4YV8A 1FH0A 3ERVA 2NQIA 1BGOA 3I06A 3KX1A 5PADA 1MHWA 2PBHA 3B79A 3KWBX 5FPWA 3CH2X 4W5CA 1NPZA 1AIMA 4WA6A 1CQDA 2DJGB 3O1GA 3PBHA 1TU6A 4FK5A 3BC3A 1BY8A 1EF7A 4X6IA 2HXZA 4BPVA 2DCBA 1AYVA 3H8CA 4Q8GA 1QOLA 1KFUL 1X9YA 2DC6A 2DZZA 5F02A 2BDLA 1GLOA 1U9WA 1EWLA 2AS8A 1U9XA 1ITOA 2PNSA 2YJ2A 4I05A 4PP2E 1CV8A 4YYVA 1O0EA 4MZOA 2AVWA 4X6JA 2GHUA 3P5UA 4YVAA 2ACTA 1PPDA 2H7JA 3N3GA 3V6CA 2DC9A 3H6SA 8PCHA 2XU5A 1PPOA 5K16A 2AU1A 2R9CA 4DMXA 4CZWA 1AU2A 2Y5BA 1GMYA 3P5VA 1F2CA 1EWMA 3E1ZB 1EWPA 1CS8A 4CDFB 1VSNA 2ARYA 1MIRA 3P5WA 4W4UA 5CVMA 2JQFR 1NB3A 2G8EA 1CPJA 3OISA 3CH3X 4ZUXU 2XU3A 4YYWA 3ZUAA 2E00A 3MHSA 1KHPA 2AIMA 2FYEA 1ZIVA 1DEUA 1U9QX 3OVZA 4N4ZA 1POPA 1F2AA 1F2BA 1STFE 2E02A
chains in the Genus database with same CATH superfamily
4BQVA 3IMAA 1AU3A 3MHHA 1ME3A 1XKGA 2HD5A 2XU4A 2OP3A 3WXEA 4YYRA 1HUCB 1YT7A 3MORA 4FJCA 4QRVA 3PDFA 4CDCB 3BPFA 4BS6A 2JRIA 1AYWA 2FQ9A 1SNKA 5A24A 3CBKA 1BQIA 3LFYA 1KFXL 4XZXA 1Y4HA 4N8WA 4KLBA 4PP1A 1K3BB 1PADA 3RNVA 3RVWA 1AECA 1PVJA 4BOZA 2B1MA 2DCDA 3B21A 1PPNA 3HWNA 1CJLA 1Q6KA 2R9FA 4AXMA 2NQDB 1YALA 1A6RA 1MEMA 2HH5A 3BCNA 1EWOA 4BSQA 3N4CA 4I04A 3D6SA 4QRGA 1PIPA 1ATKA 2AUXA 1UKFA 4D8BA 3F75A 3P5XA 2YJ8A 2FO5A 4RF1A 3HHAA 3QT4A 3BPMA 2O6XA 4AXLA 2DC7A 1PE6A 3IV2A 4HWYA 3KWZA 1QMYA 4PI3A 3PHUA 2F7DA 4P6GA 4X6HA 2NQAA 3PT2A 2P86A 3KW9A 2AYOA 3TNXA 3USVA 4GUAA 2FT2A 2NQGA 2OZ2A 3GCBA 1MS6A 1ME4A 1AU0A 4WURA 3H89A 4IP3A 2YJCA 2J7QC 5E6JA 1YVBA 4BOUA 1PBHA 3PRMA 2JTCA 2PREA 5CVNB 4I07A 5EGWA 2E01A 3RVVA 1THEA 3K8UA 3RVXA 2VHSA 1AYUA 4CDDB 4PT5A 3NHEA 5JH3A 9PAPA 3S3RA 2Z84A 1YK7A 2P7UA 4R3DA 3OF9A 2G8JA 2F1GA 2R9NA 1GCBA 4BOQA 2YJBA 2IBIA 1PPPA 3IEJA 3WXGA 1U5IA 2DCCA 3BWKA 1TL9A 3HHIA 1AU4A 3PNRA 4RNAA 1YK8A 3KKUA 1MDWA 5EF4A 3U8EA 3IHPA 2YJ9A 2J7QA 3AI8A 3H8BA 4BOSA 7PCKA 2CIOA 3PW3A 4A5UA 3E9SA 3O0UA 2VHFA 5CVOB 4YYSA 3MTNA 3N3KA 2HHNA 2ATOA 4MSXA 1GECE 4K7CA 1F29A 2AUZA 1U9VA 2IPPB 3QJ3A 4RF0A 2E03A 2C0YA 1JQPA 3C0RA 1Y08A 2R9MA 4YYQA 2R6NA 3IUTA 4OW0A 3H7DA 2B1NA 4FIPA 3QSDA 1S4VA 2DZYA 3CBJA 1KHQA 1M6DA 2R9OA 3K9MA 1ICFA 3I3TA 1MEGA 3MTVA 1PXVA 2AYNA 5CHTA 1DF0A 4MI7A 3WXFA 4YYUA 5J94A 3W31A 1PCIA 2DCAA 4XUIA 3TMPA 6PADA 4G54A 4OELA 3HD3A 3MJ5A 2JQGR 2UZJA 1CSBB 4REZA 3KSEA 3PSEA 4MZSA 4Q8HA 3TRKA 3BOWA 3K24A 4QH6A 2XU1A 4CDEB 3M99A 2BDZA 2HWKA 4BS5A 3C9EA 4DMYA 3F5VA 2G6DA 4XR7A 4OEMA 3W30A 3DF0A 2WBFX 3BY4A 5CHVA 1CTEA 1QXPA 4P16A 1TLOA 1IWDA 4BOPA 4W5BA 3OF8A 4QRXA 4IUMA 1NLJA 4MM3B 4P6EA 1KXRA 4N79A 4QBBA 1NB5A 1ZCMA 1SP4B 2Y6EA 2FTDA 5KO3A 3V6EA 2G7YA 1CB5A 2DC8A 2CB5A 1NL6A 3KFQA 1QDQA 4RY2A 2FRQA 2PADA 4HXDB 1CVZA 5JA7A 1BP4A 4PADA 2OULA 3IOQA 2DJFB 1NQCA 1VJVA 2DOSA 4RKXA 2FUDA 4ZTBA 2FE8A 3S3QA 3OVXA 2P0RA 3LXSA 1DKIA 2GFOA 2FRAA 4YV8A 1FH0A 4OVZA 3ERVA 2NQIA 1BGOA 3I06A 3KX1A 5PADA 3O65A 1MHWA 4M0WA 2PBHA 3B79A 3KWBX 5FPWA 3CH2X 4W5CA 1NPZA 1AIMA 4WA6A 1CQDA 2DJGB 3O1GA 3PBHA 3ZNHA 1TU6A 4FK5A 3BC3A 3IFUA 1BY8A 1EF7A 4X6IA 2HXZA 4BPVA 4D8EA 2DCBA 1AYVA 3H8CA 4OVZB 4Q8GA 1QOLA 1KFUL 1X9YA 2BU3A 5EZQA 2DC6A 2DZZA 3BB7A 5F02A 2BDLA 1GLOA 1U9WA 1YZBA 1EWLA 2BTWA 3PHXA 2AS8A 1U9XA 1ITOA 2PNSA 2YJ2A 4I05A 4PP2E 3PRPA 1CV8A 5EZSA 4YYVA 1O0EA 4MZOA 2AVWA 4X6JA 2GHUA 3P5UA 4YVAA 2AGAA 2ACTA 1PPDA 2H7JA 3N3GA 3V6CA 2DC9A 3H6SA 8PCHA 2XU5A 1PPOA 3PHWA 3BBAA 5K16A 2AU1A 2R9CA 4D8IA 4DMXA 4CZWA 1AU2A 2BTWB 2Y5BA 1GMYA 3P5VA 1F2CA 1EWMA 3E1ZB 3OQCA 1EWPA 1CS8A 4CDFB 1VSNA 2ARYA 1MIRA 3P5WA 4W4UA 5CVMA 2JQFR 1NB3A 2G8EA 1CPJA 3OISA 3CH3X 4ZUXU 2XU3A 4YYWA 3ZUAA 5JZEA 2E00A 3MHSA 1KHPA 2AIMA 2FYEA 1ZIVA 1DEUA 1U9QX 3OVZA 4N4ZA 1POPA 1F2AA 1F2BA 1STFE 3MP2A 2E02A
chains in the Genus database with same CATH topology
4BQVA 3IMAA 1AU3A 3MHHA 1ME3A 1XKGA 2HD5A 2XU4A 2OP3A 2VFBA 3WXEA 4YYRA 1HUCB 4GUZA 1YT7A 4BGFA 3MORA 4FJCA 4QRVA 3PDFA 4CDCB 3BPFA 4BS6A 1AYWA 2FQ9A 1SNKA 5A24A 3CBKA 1BQIA 3LFYA 1KFXL 1Y4HA 4N8WA 4KLBA 4PP1A 1K3BB 1PADA 3RVWA 1AECA 2B1MA 2DCDA 1PPNA 3HWNA 1CJLA 1Q6KA 2R9FA 4AXMA 2NQDB 1YALA 1A6RA 1MEMA 2HH5A 3BCNA 1EWOA 4BSQA 3N4CA 4I04A 3D6SA 4QRGA 1PIPA 1ATKA 2AUXA 3F75A 3P5XA 2YJ8A 1W4TA 2FO5A 3HHAA 3QT4A 3BPMA 2O6XA 4AXLA 2DC7A 1PE6A 3IV2A 4HWYA 3KWZA 1QMYA 4PI3A 2F7DA 4P6GA 4X6HA 2NQAA 4B55A 2P86A 3KW9A 2AYOA 3TNXA 3USVA 2FT2A 2NQGA 2OZ2A 3GCBA 1MS6A 1ME4A 1AU0A 3H89A 2YJCA 1YVBA 1PBHA 2PREA 5CVNB 4I07A 1W5RA 5EGWA 2E01A 3RVVA 1THEA 3K8UA 3RVXA 2VHSA 1AYUA 3D9WA 4CDDB 3NHEA 5JH3A 9PAPA 3S3RA 1YK7A 2P7UA 3OF9A 2G8JA 2F1GA 2R9NA 1GCBA 2YJBA 2IBIA 1PPPA 3IEJA 3WXGA 1U5IA 2DCCA 3BWKA 1TL9A 3HHIA 1AU4A 3PNRA 1YK8A 3KKUA 1MDWA 5EF4A 3U8EA 3IHPA 2YJ9A 3AI8A 3H8BA 7PCKA 2CIOA 3PW3A 3O0UA 2VHFA 5CVOB 4YYSA 3MTNA 3N3KA 2HHNA 2ATOA 4MSXA 1GECE 4K7CA 1F29A 2AUZA 1U9VA 3QJ3A 2IPPB 2E03A 2C0YA 1JQPA 1Y08A 2R9MA 4YYQA 2R6NA 3IUTA 4FIPA 3H7DA 2B1NA 3QSDA 1S4VA 2DZYA 3CBJA 1W6FA 1KHQA 1M6DA 2R9OA 3K9MA 1ICFA 3I3TA 1MEGA 1PXVA 2AYNA 5CHTA 1DF0A 3WXFA 4YYUA 5J94A 1PCIA 2DCAA 4XUIA 6PADA 4NV7A 4G54A 4OELA 3HD3A 2JQGR 1CSBB 3KSEA 4MZSA 4Q8HA 3BOWA 3K24A 4QH6A 2XU1A 4CDEB 3M99A 2BDZA 4BS5A 3C9EA 4DMYA 3F5VA 2G6DA 4XR7A 4OEMA 3DF0A 2WBFX 5CHVA 1CTEA 1QXPA 1TLOA 1IWDA 4W5BA 3OF8A 4QRXA 1NLJA 4P6EA 1KXRA 4N79A 4QBBA 1NB5A 1ZCMA 1SP4B 2Y6EA 2FTDA 3V6EA 2G7YA 1CB5A 2DC8A 2CB5A 1NL6A 3KFQA 1QDQA 4RY2A 2FRQA 2PADA 1CVZA 5JA7A 1BP4A 4PADA 2OULA 3IOQA 2DJFB 1NQCA 1VJVA 2FUDA 3S3QA 2BSZA 3OVXA 2P0RA 3LXSA 2GFOA 2FRAA 4YV8A 1FH0A 3ERVA 2NQIA 1BGOA 3I06A 3KX1A 5PADA 1MHWA 2PBHA 3B79A 4C5PA 3KWBX 5FPWA 3CH2X 4W5CA 1E2TA 1NPZA 1AIMA 4WA6A 1CQDA 2DJGB 3O1GA 3PBHA 1TU6A 4FK5A 3BC3A 1BY8A 1EF7A 4X6IA 2HXZA 4BPVA 2DCBA 1AYVA 3H8CA 4Q8GA 1QOLA 1KFUL 1X9YA 2DC6A 2DZZA 5F02A 2BDLA 1GLOA 1U9WA 1EWLA 3LTWA 2AS8A 1U9XA 1ITOA 2PNSA 2YJ2A 4I05A 4PP2E 1CV8A 4YYVA 1O0EA 4MZOA 2AVWA 4X6JA 2GHUA 3P5UA 4YVAA 2ACTA 1PPDA 2H7JA 3N3GA 3V6CA 2DC9A 3H6SA 8PCHA 2XU5A 1PPOA 5K16A 2AU1A 2R9CA 4DMXA 4CZWA 1AU2A 2Y5BA 1GMYA 3P5VA 1F2CA 1EWMA 3E1ZB 1EWPA 1CS8A 4CDFB 1VSNA 2ARYA 1GX3A 1MIRA 3P5WA 4NV8A 4W4UA 5CVMA 2VFCA 2JQFR 1NB3A 2G8EA 1CPJA 3OISA 3CH3X 4ZUXU 2XU3A 4YYWA 3ZUAA 2E00A 3MHSA 1KHPA 2AIMA 2FYEA 1ZIVA 1DEUA 1U9QX 3OVZA 4N4ZA 1POPA 1F2AA 1F2BA 1STFE 2E02A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BQV A;  3IMA A;  1AU3 A;  3MHH A;  1ME3 A;  1XKG A;  2HD5 A;  2XU4 A;  2OP3 A;  3WXE A;  4YYR A;  1HUC B;  1YT7 A;  3MOR A;  4FJC A;  4QRV A;  3PDF A;  4CDC B;  3BPF A;  4BS6 A;  1AYW A;  2FQ9 A;  1SNK A;  5A24 A;  3CBK A;  1BQI A;  3LFY A;  1KFX L;  1Y4H A;  4N8W A;  4KLB A;  4PP1 A;  1K3B B;  1PAD A;  3RVW A;  1AEC A;  2B1M A;  2DCD A;  1PPN A;  3HWN A;  1CJL A;  1Q6K A;  2R9F A;  4AXM A;  2NQD B;  1YAL A;  1A6R A;  1MEM A;  2HH5 A;  3BCN A;  1EWO A;  4BSQ A;  3N4C A;  4I04 A;  3D6S A;  4QRG A;  1PIP A;  1ATK A;  2AUX A;  3F75 A;  3P5X A;  2YJ8 A;  2FO5 A;  3HHA A;  3QT4 A;  3BPM A;  2O6X A;  4AXL A;  2DC7 A;  1PE6 A;  3IV2 A;  4HWY A;  3KWZ A;  1QMY A;  4PI3 A;  2F7D A;  4P6G A;  4X6H A;  2NQA A;  2P86 A;  3KW9 A;  2AYO A;  3TNX A;  3USV A;  2FT2 A;  2NQG A;  2OZ2 A;  3GCB A;  1MS6 A;  1ME4 A;  1AU0 A;  3H89 A;  2YJC A;  1YVB A;  1PBH A;  2PRE A;  5CVN B;  4I07 A;  5EGW A;  2E01 A;  3RVV A;  1THE A;  3K8U A;  3RVX A;  2VHS A;  1AYU A;  4CDD B;  3NHE A;  5JH3 A;  9PAP A;  3S3R A;  1YK7 A;  2P7U A;  3OF9 A;  2G8J A;  2F1G A;  2R9N A;  1GCB A;  2YJB A;  2IBI A;  1PPP A;  3IEJ A;  3WXG A;  1U5I A;  2DCC A;  3BWK A;  1TL9 A;  3HHI A;  1AU4 A;  3PNR A;  1YK8 A;  3KKU A;  1MDW A;  5EF4 A;  3U8E A;  3IHP A;  2YJ9 A;  3AI8 A;  3H8B A;  7PCK A;  2CIO A;  3PW3 A;  3O0U A;  2VHF A;  5CVO B;  4YYS A;  3MTN A;  3N3K A;  2HHN A;  2ATO A;  4MSX A;  1GEC E;  4K7C A;  1F29 A;  2AUZ A;  1U9V A;  3QJ3 A;  2IPP B;  2E03 A;  2C0Y A;  1JQP A;  1Y08 A;  2R9M A;  4YYQ A;  2R6N A;  3IUT A;  4FIP A;  3H7D A;  2B1N A;  3QSD A;  1S4V A;  2DZY A;  3CBJ A;  1KHQ A;  1M6D A;  2R9O A;  3K9M A;  1ICF A;  3I3T A;  1MEG A;  1PXV A;  2AYN A;  5CHT A;  1DF0 A;  3WXF A;  4YYU A;  5J94 A;  1PCI A;  2DCA A;  4XUI A;  6PAD A;  4G54 A;  4OEL A;  3HD3 A;  2JQG R;  1CSB B;  3KSE A;  4MZS A;  4Q8H A;  3BOW A;  3K24 A;  4QH6 A;  2XU1 A;  4CDE B;  3M99 A;  2BDZ A;  4BS5 A;  3C9E A;  4DMY A;  3F5V A;  2G6D A;  4XR7 A;  4OEM A;  3DF0 A;  2WBF X;  5CHV A;  1CTE A;  1QXP A;  1TLO A;  1IWD A;  4W5B A;  3OF8 A;  4QRX A;  1NLJ A;  4P6E A;  1KXR A;  4N79 A;  4QBB A;  1NB5 A;  1ZCM A;  1SP4 B;  2Y6E A;  2FTD A;  3V6E A;  2G7Y A;  1CB5 A;  2DC8 A;  2CB5 A;  1NL6 A;  3KFQ A;  1QDQ A;  4RY2 A;  2FRQ A;  2PAD A;  1CVZ A;  5JA7 A;  1BP4 A;  4PAD A;  2OUL A;  3IOQ A;  2DJF B;  1NQC A;  1VJV A;  2FUD A;  3S3Q A;  3OVX A;  2P0R A;  3LXS A;  2GFO A;  2FRA A;  4YV8 A;  1FH0 A;  3ERV A;  2NQI A;  1BGO A;  3I06 A;  3KX1 A;  5PAD A;  1MHW A;  2PBH A;  3B79 A;  3KWB X;  5FPW A;  3CH2 X;  4W5C A;  1NPZ A;  1AIM A;  4WA6 A;  1CQD A;  2DJG B;  3O1G A;  3PBH A;  1TU6 A;  4FK5 A;  3BC3 A;  1BY8 A;  1EF7 A;  4X6I A;  2HXZ A;  4BPV A;  2DCB A;  1AYV A;  3H8C A;  4Q8G A;  1QOL A;  1KFU L;  1X9Y A;  2DC6 A;  2DZZ A;  5F02 A;  2BDL A;  1GLO A;  1U9W A;  1EWL A;  2AS8 A;  1U9X A;  1ITO A;  2PNS A;  2YJ2 A;  4I05 A;  4PP2 E;  1CV8 A;  4YYV A;  1O0E A;  4MZO A;  2AVW A;  4X6J A;  2GHU A;  3P5U A;  4YVA A;  2ACT A;  1PPD A;  2H7J A;  3N3G A;  3V6C A;  2DC9 A;  3H6S A;  8PCH A;  2XU5 A;  1PPO A;  5K16 A;  2AU1 A;  2R9C A;  4DMX A;  4CZW A;  1AU2 A;  2Y5B A;  1GMY A;  3P5V A;  1F2C A;  1EWM A;  3E1Z B;  1EWP A;  1CS8 A;  4CDF B;  1VSN A;  2ARY A;  1MIR A;  3P5W A;  4W4U A;  5CVM A;  2JQF R;  1NB3 A;  2G8E A;  1CPJ A;  3OIS A;  3CH3 X;  4ZUX U;  2XU3 A;  4YYW A;  3ZUA A;  2E00 A;  3MHS A;  1KHP A;  2AIM A;  2FYE A;  1ZIV A;  1DEU A;  1U9Q X;  3OVZ A;  4N4Z A;  1POP A;  1F2A A;  1F2B A;  1STF E;  2E02 A; 
#chains in the Genus database with same CATH topology
 4BQV A;  3IMA A;  1AU3 A;  3MHH A;  1ME3 A;  1XKG A;  2HD5 A;  2XU4 A;  2OP3 A;  3WXE A;  4YYR A;  1HUC B;  1YT7 A;  3MOR A;  4FJC A;  4QRV A;  3PDF A;  4CDC B;  3BPF A;  4BS6 A;  2JRI A;  1AYW A;  2FQ9 A;  1SNK A;  5A24 A;  3CBK A;  1BQI A;  3LFY A;  1KFX L;  4XZX A;  1Y4H A;  4N8W A;  4KLB A;  4PP1 A;  1K3B B;  1PAD A;  3RNV A;  3RVW A;  1AEC A;  1PVJ A;  4BOZ A;  2B1M A;  2DCD A;  3B21 A;  1PPN A;  3HWN A;  1CJL A;  1Q6K A;  2R9F A;  4AXM A;  2NQD B;  1YAL A;  1A6R A;  1MEM A;  2HH5 A;  3BCN A;  1EWO A;  4BSQ A;  3N4C A;  4I04 A;  3D6S A;  4QRG A;  1PIP A;  1ATK A;  2AUX A;  1UKF A;  4D8B A;  3F75 A;  3P5X A;  2YJ8 A;  2FO5 A;  4RF1 A;  3HHA A;  3QT4 A;  3BPM A;  2O6X A;  4AXL A;  2DC7 A;  1PE6 A;  3IV2 A;  4HWY A;  3KWZ A;  1QMY A;  4PI3 A;  3PHU A;  2F7D A;  4P6G A;  4X6H A;  2NQA A;  3PT2 A;  2P86 A;  3KW9 A;  2AYO A;  3TNX A;  3USV A;  4GUA A;  2FT2 A;  2NQG A;  2OZ2 A;  3GCB A;  1MS6 A;  1ME4 A;  1AU0 A;  4WUR A;  3H89 A;  4IP3 A;  2YJC A;  2J7Q C;  5E6J A;  1YVB A;  4BOU A;  1PBH A;  3PRM A;  2JTC A;  2PRE A;  5CVN B;  4I07 A;  5EGW A;  2E01 A;  3RVV A;  1THE A;  3K8U A;  3RVX A;  2VHS A;  1AYU A;  4CDD B;  4PT5 A;  3NHE A;  5JH3 A;  9PAP A;  3S3R A;  2Z84 A;  1YK7 A;  2P7U A;  4R3D A;  3OF9 A;  2G8J A;  2F1G A;  2R9N A;  1GCB A;  4BOQ A;  2YJB A;  2IBI A;  1PPP A;  3IEJ A;  3WXG A;  1U5I A;  2DCC A;  3BWK A;  1TL9 A;  3HHI A;  1AU4 A;  3PNR A;  4RNA A;  1YK8 A;  3KKU A;  1MDW A;  5EF4 A;  3U8E A;  3IHP A;  2YJ9 A;  2J7Q A;  3AI8 A;  3H8B A;  4BOS A;  7PCK A;  2CIO A;  3PW3 A;  4A5U A;  3E9S A;  3O0U A;  2VHF A;  5CVO B;  4YYS A;  3MTN A;  3N3K A;  2HHN A;  2ATO A;  4MSX A;  1GEC E;  4K7C A;  1F29 A;  2AUZ A;  1U9V A;  2IPP B;  3QJ3 A;  4RF0 A;  2E03 A;  2C0Y A;  1JQP A;  3C0R A;  1Y08 A;  2R9M A;  4YYQ A;  2R6N A;  3IUT A;  4OW0 A;  3H7D A;  2B1N A;  4FIP A;  3QSD A;  1S4V A;  2DZY A;  3CBJ A;  1KHQ A;  1M6D A;  2R9O A;  3K9M A;  1ICF A;  3I3T A;  1MEG A;  3MTV A;  1PXV A;  2AYN A;  5CHT A;  1DF0 A;  4MI7 A;  3WXF A;  4YYU A;  5J94 A;  3W31 A;  1PCI A;  2DCA A;  4XUI A;  3TMP A;  6PAD A;  4G54 A;  4OEL A;  3HD3 A;  3MJ5 A;  2JQG R;  2UZJ A;  1CSB B;  4REZ A;  3KSE A;  3PSE A;  4MZS A;  4Q8H A;  3TRK A;  3BOW A;  3K24 A;  4QH6 A;  2XU1 A;  4CDE B;  3M99 A;  2BDZ A;  2HWK A;  4BS5 A;  3C9E A;  4DMY A;  3F5V A;  2G6D A;  4XR7 A;  4OEM A;  3W30 A;  3DF0 A;  2WBF X;  3BY4 A;  5CHV A;  1CTE A;  1QXP A;  4P16 A;  1TLO A;  1IWD A;  4BOP A;  4W5B A;  3OF8 A;  4QRX A;  4IUM A;  1NLJ A;  4MM3 B;  4P6E A;  1KXR A;  4N79 A;  4QBB A;  1NB5 A;  1ZCM A;  1SP4 B;  2Y6E A;  2FTD A;  5KO3 A;  3V6E A;  2G7Y A;  1CB5 A;  2DC8 A;  2CB5 A;  1NL6 A;  3KFQ A;  1QDQ A;  4RY2 A;  2FRQ A;  2PAD A;  4HXD B;  1CVZ A;  5JA7 A;  1BP4 A;  4PAD A;  2OUL A;  3IOQ A;  2DJF B;  1NQC A;  1VJV A;  2DOS A;  4RKX A;  2FUD A;  4ZTB A;  2FE8 A;  3S3Q A;  3OVX A;  2P0R A;  3LXS A;  1DKI A;  2GFO A;  2FRA A;  4YV8 A;  1FH0 A;  4OVZ A;  3ERV A;  2NQI A;  1BGO A;  3I06 A;  3KX1 A;  5PAD A;  3O65 A;  1MHW A;  4M0W A;  2PBH A;  3B79 A;  3KWB X;  5FPW A;  3CH2 X;  4W5C A;  1NPZ A;  1AIM A;  4WA6 A;  1CQD A;  2DJG B;  3O1G A;  3PBH A;  3ZNH A;  1TU6 A;  4FK5 A;  3BC3 A;  3IFU A;  1BY8 A;  1EF7 A;  4X6I A;  2HXZ A;  4BPV A;  4D8E A;  2DCB A;  1AYV A;  3H8C A;  4OVZ B;  4Q8G A;  1QOL A;  1KFU L;  1X9Y A;  2BU3 A;  5EZQ A;  2DC6 A;  2DZZ A;  3BB7 A;  5F02 A;  2BDL A;  1GLO A;  1U9W A;  1YZB A;  1EWL A;  2BTW A;  3PHX A;  2AS8 A;  1U9X A;  1ITO A;  2PNS A;  2YJ2 A;  4I05 A;  4PP2 E;  3PRP A;  1CV8 A;  5EZS A;  4YYV A;  1O0E A;  4MZO A;  2AVW A;  4X6J A;  2GHU A;  3P5U A;  4YVA A;  2AGA A;  2ACT A;  1PPD A;  2H7J A;  3N3G A;  3V6C A;  2DC9 A;  3H6S A;  8PCH A;  2XU5 A;  1PPO A;  3PHW A;  3BBA A;  5K16 A;  2AU1 A;  2R9C A;  4D8I A;  4DMX A;  4CZW A;  1AU2 A;  2BTW B;  2Y5B A;  1GMY A;  3P5V A;  1F2C A;  1EWM A;  3E1Z B;  3OQC A;  1EWP A;  1CS8 A;  4CDF B;  1VSN A;  2ARY A;  1MIR A;  3P5W A;  4W4U A;  5CVM A;  2JQF R;  1NB3 A;  2G8E A;  1CPJ A;  3OIS A;  3CH3 X;  4ZUX U;  2XU3 A;  4YYW A;  3ZUA A;  5JZE A;  2E00 A;  3MHS A;  1KHP A;  2AIM A;  2FYE A;  1ZIV A;  1DEU A;  1U9Q X;  3OVZ A;  4N4Z A;  1POP A;  1F2A A;  1F2B A;  1STF E;  3MP2 A;  2E02 A; 
#chains in the Genus database with same CATH homology
 4BQV A;  3IMA A;  1AU3 A;  3MHH A;  1ME3 A;  1XKG A;  2HD5 A;  2XU4 A;  2OP3 A;  2VFB A;  3WXE A;  4YYR A;  1HUC B;  4GUZ A;  1YT7 A;  4BGF A;  3MOR A;  4FJC A;  4QRV A;  3PDF A;  4CDC B;  3BPF A;  4BS6 A;  1AYW A;  2FQ9 A;  1SNK A;  5A24 A;  3CBK A;  1BQI A;  3LFY A;  1KFX L;  1Y4H A;  4N8W A;  4KLB A;  4PP1 A;  1K3B B;  1PAD A;  3RVW A;  1AEC A;  2B1M A;  2DCD A;  1PPN A;  3HWN A;  1CJL A;  1Q6K A;  2R9F A;  4AXM A;  2NQD B;  1YAL A;  1A6R A;  1MEM A;  2HH5 A;  3BCN A;  1EWO A;  4BSQ A;  3N4C A;  4I04 A;  3D6S A;  4QRG A;  1PIP A;  1ATK A;  2AUX A;  3F75 A;  3P5X A;  2YJ8 A;  1W4T A;  2FO5 A;  3HHA A;  3QT4 A;  3BPM A;  2O6X A;  4AXL A;  2DC7 A;  1PE6 A;  3IV2 A;  4HWY A;  3KWZ A;  1QMY A;  4PI3 A;  2F7D A;  4P6G A;  4X6H A;  2NQA A;  4B55 A;  2P86 A;  3KW9 A;  2AYO A;  3TNX A;  3USV A;  2FT2 A;  2NQG A;  2OZ2 A;  3GCB A;  1MS6 A;  1ME4 A;  1AU0 A;  3H89 A;  2YJC A;  1YVB A;  1PBH A;  2PRE A;  5CVN B;  4I07 A;  1W5R A;  5EGW A;  2E01 A;  3RVV A;  1THE A;  3K8U A;  3RVX A;  2VHS A;  1AYU A;  3D9W A;  4CDD B;  3NHE A;  5JH3 A;  9PAP A;  3S3R A;  1YK7 A;  2P7U A;  3OF9 A;  2G8J A;  2F1G A;  2R9N A;  1GCB A;  2YJB A;  2IBI A;  1PPP A;  3IEJ A;  3WXG A;  1U5I A;  2DCC A;  3BWK A;  1TL9 A;  3HHI A;  1AU4 A;  3PNR A;  1YK8 A;  3KKU A;  1MDW A;  5EF4 A;  3U8E A;  3IHP A;  2YJ9 A;  3AI8 A;  3H8B A;  7PCK A;  2CIO A;  3PW3 A;  3O0U A;  2VHF A;  5CVO B;  4YYS A;  3MTN A;  3N3K A;  2HHN A;  2ATO A;  4MSX A;  1GEC E;  4K7C A;  1F29 A;  2AUZ A;  1U9V A;  3QJ3 A;  2IPP B;  2E03 A;  2C0Y A;  1JQP A;  1Y08 A;  2R9M A;  4YYQ A;  2R6N A;  3IUT A;  4FIP A;  3H7D A;  2B1N A;  3QSD A;  1S4V A;  2DZY A;  3CBJ A;  1W6F A;  1KHQ A;  1M6D A;  2R9O A;  3K9M A;  1ICF A;  3I3T A;  1MEG A;  1PXV A;  2AYN A;  5CHT A;  1DF0 A;  3WXF A;  4YYU A;  5J94 A;  1PCI A;  2DCA A;  4XUI A;  6PAD A;  4NV7 A;  4G54 A;  4OEL A;  3HD3 A;  2JQG R;  1CSB B;  3KSE A;  4MZS A;  4Q8H A;  3BOW A;  3K24 A;  4QH6 A;  2XU1 A;  4CDE B;  3M99 A;  2BDZ A;  4BS5 A;  3C9E A;  4DMY A;  3F5V A;  2G6D A;  4XR7 A;  4OEM A;  3DF0 A;  2WBF X;  5CHV A;  1CTE A;  1QXP A;  1TLO A;  1IWD A;  4W5B A;  3OF8 A;  4QRX A;  1NLJ A;  4P6E A;  1KXR A;  4N79 A;  4QBB A;  1NB5 A;  1ZCM A;  1SP4 B;  2Y6E A;  2FTD A;  3V6E A;  2G7Y A;  1CB5 A;  2DC8 A;  2CB5 A;  1NL6 A;  3KFQ A;  1QDQ A;  4RY2 A;  2FRQ A;  2PAD A;  1CVZ A;  5JA7 A;  1BP4 A;  4PAD A;  2OUL A;  3IOQ A;  2DJF B;  1NQC A;  1VJV A;  2FUD A;  3S3Q A;  2BSZ A;  3OVX A;  2P0R A;  3LXS A;  2GFO A;  2FRA A;  4YV8 A;  1FH0 A;  3ERV A;  2NQI A;  1BGO A;  3I06 A;  3KX1 A;  5PAD A;  1MHW A;  2PBH A;  3B79 A;  4C5P A;  3KWB X;  5FPW A;  3CH2 X;  4W5C A;  1E2T A;  1NPZ A;  1AIM A;  4WA6 A;  1CQD A;  2DJG B;  3O1G A;  3PBH A;  1TU6 A;  4FK5 A;  3BC3 A;  1BY8 A;  1EF7 A;  4X6I A;  2HXZ A;  4BPV A;  2DCB A;  1AYV A;  3H8C A;  4Q8G A;  1QOL A;  1KFU L;  1X9Y A;  2DC6 A;  2DZZ A;  5F02 A;  2BDL A;  1GLO A;  1U9W A;  1EWL A;  3LTW A;  2AS8 A;  1U9X A;  1ITO A;  2PNS A;  2YJ2 A;  4I05 A;  4PP2 E;  1CV8 A;  4YYV A;  1O0E A;  4MZO A;  2AVW A;  4X6J A;  2GHU A;  3P5U A;  4YVA A;  2ACT A;  1PPD A;  2H7J A;  3N3G A;  3V6C A;  2DC9 A;  3H6S A;  8PCH A;  2XU5 A;  1PPO A;  5K16 A;  2AU1 A;  2R9C A;  4DMX A;  4CZW A;  1AU2 A;  2Y5B A;  1GMY A;  3P5V A;  1F2C A;  1EWM A;  3E1Z B;  1EWP A;  1CS8 A;  4CDF B;  1VSN A;  2ARY A;  1GX3 A;  1MIR A;  3P5W A;  4NV8 A;  4W4U A;  5CVM A;  2VFC A;  2JQF R;  1NB3 A;  2G8E A;  1CPJ A;  3OIS A;  3CH3 X;  4ZUX U;  2XU3 A;  4YYW A;  3ZUA A;  2E00 A;  3MHS A;  1KHP A;  2AIM A;  2FYE A;  1ZIV A;  1DEU A;  1U9Q X;  3OVZ A;  4N4Z A;  1POP A;  1F2A A;  1F2B A;  1STF E;  2E02 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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