1HUCB

The refined 2.15 angstroms x-ray crystal structure of human liver cathepsin b: the structural basis for its specificity
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
205
structure length
205
Chain Sequence
VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity.
pubmed rcsb
molecule tags Thiol protease
source organism Homo sapiens
molecule keywords CATHEPSIN B
total genus 49
structure length 205
sequence length 205
chains with identical sequence D
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 1993-04-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1hucB00
4DMXA 2AVWA 1S4VA 1PPNA 3OISA 1PBHA 3D6SA 3ZUAA 3V6EA 1PCIA 2VHSA 2E01A 2AS8A 3K9MA 3P5VA 2DCBA 5CVMA 1SNKA 2HXZA 1DF0A 1K3BB 1MEGA 4YVAA 3PNRA 1XKGA 4K7CA 3F5VA 2OULA 3O1GA 2Y5BA 2AYOA 1MEMA 2DC9A 3NHEA 2HD5A 4YV8A 2OZ2A 3LXSA 3OF8A 4AXLA 1Q6KA 2DJGB 4RY2A 1MHWA 1U5IA 1GCBA 4CDCB 4YYSA 2PNSA 4X6JA 2CIOA 4W5CA 2FRQA 1QDQA 4CZWA 5PADA 4N4ZA 3N4CA 4BQVA 3IOQA 2NQGA 2FO5A 2H7JA 2XU3A 1F2AA 1A6RA 2XU4A 1PIPA 1KFUL 2DC8A 1TLOA 4W4UA 4FK5A 1MS6A 3OF9A 3H6SA 2IPPB 2FT2A 2JQFR 1AECA 3PW3A 3S3QA 2FRAA 1EWMA 3S3RA 5EF4A 3HWNA 4MSXA 3WXFA 4OELA 2O6XA 3P5WA 1CTEA 3K8UA 3MORA 4QBBA 1AU3A 2BDLA 2R6NA 3H89A 7PCKA 2DC7A 3I3TA 4HWYA 3U8EA 1TU6A 2NQAA 1X9YA 4PADA 4Q8GA 2JQGR 4MZSA 3BCNA 4QH6A 2HH5A 3CH3X 1JQPA 1SP4B 1MDWA 4PI3A 1O0EA 3KSEA 5F02A 1M6DA 3N3KA 1NB5A 1CQDA 3KFQA 4QRXA 2YJ2A 3K24A 2R9MA 1GECE 1AYUA 4QRGA 1F29A 1Y4HA 4PP2E 1U9XA 1EWLA 2G8EA 5JH3A 5CHVA 3M99A 2R9CA 1MIRA 4I05A 2Y6EA 2DZYA 4YYRA 3CH2X 3RVWA 2F7DA 5J94A 3IMAA 4BS6A 1DEUA 4XR7A 2B1MA 3MHHA 2DJFB 2ARYA 4P6EA 4XUIA 5A24A 1ITOA 3HD3A 1ATKA 3MHSA 2YJ8A 4KLBA 2PREA 1CJLA 3HHAA 1AU4A 1PPOA 3H7DA 1EWOA 4N79A 2P0RA 3IUTA 4FIPA 3BWKA 3E1ZB 1QMYA 4ZUXU 1KFXL 1PXVA 2R9FA 3H8CA 3WXGA 1YK8A 5K16A 2G7YA 1IWDA 6PADA 2VHFA 1PPDA 3BPMA 8PCHA 5CHTA 2OP3A 3CBJA 3PBHA 1KXRA 3QT4A 4AXMA 2F1GA 1THEA 1BQIA 1VJVA 4N8WA 1CV8A 3GCBA 4MZOA 4CDEB 4DMYA 1HUCB 2E00A 5EGWA 1CB5A 3CBKA 3C9EA 4X6IA 1CS8A 3F75A 2ACTA 4PP1A 2YJCA 1NLJA 2B1NA 2XU5A 2AIMA 4OEMA 4YYQA 1QOLA 3V6CA 1VSNA 1NPZA 3IEJA 2YJBA 1EWPA 3TNXA 1YVBA 2CB5A 1F2CA 1ME4A 2DCCA 1GLOA 3WXEA 3IV2A 3KWBX 1AIMA 2G8JA 1NB3A 2P7UA 1U9WA 5JA7A 3H8BA 4CDDB 4I07A 1YK7A 3RVXA 1EF7A 2AU1A 2FQ9A 1PADA 2XU1A 2E03A 2R9NA 1STFE 1CPJA 2ATOA 1PPPA 4YYVA 2AUXA 3O0UA 4QRVA 1KHPA 1NQCA 1BY8A 1ICFA 4BS5A 2FTDA 3OVXA 2G6DA 4YYWA 4P6GA 2DC6A 3P5XA 5CVOB 4CDFB 1BP4A 1AU0A 2AYNA 3P5UA 1ZIVA 3KWZA 5FPWA 3BPFA 2BDZA 2GHUA 3ERVA 1ME3A 3OVZA 1KHQA 1PE6A 2FYEA 2DZZA 3IHPA 4BSQA 1NL6A 1YT7A 2DCDA 3KKUA 1AYVA 3B79A 4X6HA 1Y08A 4BPVA 1U9QX 3BC3A 4I04A 4W5BA 3QJ3A 2DCAA 1YALA 1U9VA 2IBIA 9PAPA 5CVNB 3MTNA 2E02A 2C0YA 4Q8HA 2YJ9A 1AU2A 4G54A 1POPA 4WA6A 1F2BA 2WBFX 1CSBB 3HHIA 3DF0A 2PADA 1GMYA 3USVA 3KW9A 2R9OA 3N3GA 4FJCA 3LFYA 2NQIA 1TL9A 3AI8A 3QSDA 1ZCMA 1QXPA 3BOWA 1AYWA 3I06A 2P86A 2FUDA 2HHNA 3RVVA 1CVZA 1BGOA 2GFOA 2NQDB 3KX1A 2PBHA 1FH0A 2AUZA 4YYUA 3PDFA
chains in the Genus database with same CATH superfamily
4DMXA 2AVWA 4PT5A 1S4VA 1PPNA 3OISA 1PBHA 3D6SA 4RKXA 3ZUAA 3V6EA 1PCIA 2VHSA 2E01A 2AS8A 3K9MA 3P5VA 2DCBA 5CVMA 1SNKA 2HXZA 4OW0A 1DF0A 1K3BB 1MEGA 4YVAA 3PNRA 1XKGA 4K7CA 3F5VA 2OULA 3O1GA 2Y5BA 2AYOA 1MEMA 2DC9A 3NHEA 2HD5A 4YV8A 2OZ2A 3LXSA 3OF8A 4AXLA 4GUAA 1Q6KA 4BOPA 2DJGB 4RY2A 3PHUA 1MHWA 2HWKA 1U5IA 1GCBA 3O65A 4CDCB 4YYSA 2PNSA 4X6JA 5E6JA 2CIOA 4W5CA 2FRQA 1QDQA 4BOZA 4CZWA 5PADA 4N4ZA 3N4CA 3PT2A 4BQVA 3IOQA 2NQGA 2FO5A 2H7JA 2XU3A 1F2AA 2JRIA 1A6RA 2XU4A 1PIPA 2BU3A 1KFUL 2DC8A 1TLOA 4W4UA 4FK5A 1MS6A 3OF9A 3H6SA 2IPPB 2FT2A 2JQFR 1AECA 3PW3A 3S3QA 3BY4A 2FRAA 1EWMA 3S3RA 5EF4A 3HWNA 5KO3A 4HXDB 4MSXA 3WXFA 4OELA 4OVZB 2O6XA 3P5WA 1CTEA 3K8UA 3MORA 4QBBA 1AU3A 2BDLA 2R6NA 3H89A 2DOSA 7PCKA 2DC7A 3I3TA 2FE8A 4HWYA 1TU6A 2NQAA 3U8EA 4IP3A 4M0WA 1X9YA 4PADA 4Q8GA 2JQGR 4MZSA 3BCNA 4QH6A 2HH5A 3CH3X 1JQPA 1SP4B 1MDWA 3MP2A 4PI3A 5JZEA 1O0EA 3KSEA 5F02A 1M6DA 3N3KA 1NB5A 1CQDA 3KFQA 4QRXA 2YJ2A 3K24A 2R9MA 1GECE 1AYUA 4QRGA 3IFUA 3B21A 1F29A 1Y4HA 4PP2E 1U9XA 1EWLA 2G8EA 5JH3A 5CHVA 4IUMA 3M99A 4MM3B 2R9CA 3PHXA 3MTVA 1MIRA 4I05A 4RF0A 2BTWB 2Y6EA 2DZYA 4YYRA 3CH2X 3RVWA 2F7DA 5J94A 3IMAA 4BS6A 1DEUA 4XR7A 4A5UA 2B1MA 3MHHA 2DJFB 2ARYA 4P6EA 3PRPA 4XUIA 5A24A 1ITOA 3HD3A 1ATKA 3MHSA 2YJ8A 4KLBA 2PREA 1CJLA 3HHAA 1AU4A 1PPOA 3H7DA 1EWOA 4N79A 2P0RA 3IUTA 4FIPA 3BWKA 3E1ZB 1QMYA 4ZUXU 1KFXL 1PXVA 2R9FA 4XZXA 3H8CA 2J7QC 3WXGA 4WURA 1YK8A 5K16A 2UZJA 2G7YA 1IWDA 6PADA 2VHFA 1PPDA 3BPMA 8PCHA 5CHTA 2Z84A 2OP3A 3CBJA 2AGAA 3PBHA 1KXRA 4RNAA 3QT4A 4AXMA 2F1GA 1THEA 1BQIA 1VJVA 4N8WA 1CV8A 3GCBA 4MZOA 4BOQA 4CDEB 4DMYA 1HUCB 2E00A 3W31A 3E9SA 5EGWA 1CB5A 3CBKA 3C9EA 4X6IA 1CS8A 3F75A 2ACTA 4PP1A 2YJCA 1NLJA 4OVZA 5EZQA 2B1NA 2XU5A 2AIMA 4OEMA 4YYQA 1QOLA 3V6CA 1VSNA 1NPZA 2J7QA 3IEJA 2YJBA 1EWPA 3TNXA 1YVBA 2CB5A 1F2CA 1ME4A 2DCCA 1GLOA 3WXEA 3IV2A 1YZBA 3KWBX 1AIMA 2G8JA 4BOSA 4D8EA 1NB3A 3BB7A 2P7UA 1U9WA 5JA7A 3H8BA 4CDDB 4I07A 3ZNHA 1YK7A 3MJ5A 3RVXA 4D8IA 1EF7A 2AU1A 2FQ9A 3TRKA 1PADA 2XU1A 3PHWA 2E03A 1UKFA 2R9NA 1STFE 1CPJA 2ATOA 1PPPA 4YYVA 3PRMA 2AUXA 3O0UA 4QRVA 1KHPA 2JTCA 1NQCA 1BY8A 2BTWA 1ICFA 4BS5A 2FTDA 3OVXA 2G6DA 4YYWA 5EZSA 4ZTBA 4P6GA 2DC6A 3P5XA 5CVOB 4CDFB 1BP4A 1AU0A 2AYNA 3P5UA 3W30A 1ZIVA 3KWZA 5FPWA 3BPFA 2BDZA 3RNVA 2GHUA 3ERVA 1ME3A 3OVZA 1KHQA 1PE6A 2FYEA 3TMPA 2DZZA 3IHPA 4BSQA 1NL6A 1YT7A 4D8BA 3PSEA 2DCDA 3KKUA 1AYVA 3B79A 4X6HA 4RF1A 1Y08A 4BPVA 1U9QX 3BC3A 4I04A 4W5BA 3QJ3A 2DCAA 1YALA 1U9VA 3BBAA 2IBIA 9PAPA 5CVNB 3MTNA 2E02A 2C0YA 4Q8HA 2YJ9A 1AU2A 4REZA 4G54A 1POPA 4WA6A 1F2BA 2WBFX 4MI7A 1CSBB 3HHIA 3OQCA 3DF0A 2PADA 1PVJA 1GMYA 3USVA 3KW9A 2R9OA 3N3GA 4FJCA 3LFYA 2NQIA 1TL9A 3AI8A 3QSDA 1ZCMA 1QXPA 3BOWA 3C0RA 1AYWA 3I06A 4BOUA 2P86A 2FUDA 2HHNA 1DKIA 4P16A 4R3DA 3RVVA 1CVZA 1BGOA 2GFOA 2NQDB 3KX1A 2PBHA 1FH0A 2AUZA 4YYUA 3PDFA
chains in the Genus database with same CATH topology
4DMXA 2AVWA 1S4VA 1W4TA 1PPNA 3OISA 1PBHA 3D6SA 3ZUAA 3V6EA 1PCIA 2VHSA 2E01A 2AS8A 3K9MA 3P5VA 2DCBA 5CVMA 1SNKA 2HXZA 1DF0A 1K3BB 4BGFA 1MEGA 4YVAA 3PNRA 1XKGA 4K7CA 3F5VA 2OULA 3O1GA 2Y5BA 4NV7A 2AYOA 1MEMA 2DC9A 3NHEA 2HD5A 4YV8A 2OZ2A 3LXSA 3OF8A 4AXLA 1Q6KA 2DJGB 4RY2A 1MHWA 1U5IA 1GCBA 4CDCB 4YYSA 2PNSA 4X6JA 2CIOA 4W5CA 2FRQA 1QDQA 4CZWA 5PADA 4N4ZA 3N4CA 4BQVA 3IOQA 2NQGA 2FO5A 2H7JA 2XU3A 1F2AA 1A6RA 2XU4A 1PIPA 4C5PA 1KFUL 2DC8A 1TLOA 4W4UA 4FK5A 1MS6A 3OF9A 3H6SA 2IPPB 2FT2A 2JQFR 1AECA 3PW3A 3S3QA 2FRAA 1EWMA 3S3RA 5EF4A 3HWNA 4MSXA 3WXFA 4OELA 2O6XA 3P5WA 1CTEA 3K8UA 3MORA 4QBBA 1AU3A 2BDLA 2R6NA 3H89A 7PCKA 2DC7A 3I3TA 4HWYA 3U8EA 1TU6A 2NQAA 1X9YA 4PADA 4Q8GA 2JQGR 4MZSA 3BCNA 4QH6A 2HH5A 3CH3X 1JQPA 1SP4B 1MDWA 4PI3A 1O0EA 3KSEA 5F02A 1M6DA 3N3KA 1NB5A 1CQDA 3KFQA 4QRXA 2YJ2A 3K24A 2R9MA 1GECE 1AYUA 4QRGA 1F29A 2VFCA 1Y4HA 4PP2E 1U9XA 1EWLA 2G8EA 5JH3A 5CHVA 3M99A 2R9CA 1MIRA 4I05A 2Y6EA 2DZYA 4YYRA 3CH2X 3RVWA 2F7DA 5J94A 3D9WA 1W6FA 3IMAA 4BS6A 1DEUA 4XR7A 2B1MA 3MHHA 2DJFB 2ARYA 4P6EA 4XUIA 5A24A 1ITOA 3HD3A 1ATKA 3MHSA 4GUZA 2YJ8A 4KLBA 2PREA 1CJLA 3HHAA 1AU4A 1PPOA 3H7DA 1EWOA 4N79A 2P0RA 3IUTA 4FIPA 3BWKA 3E1ZB 1QMYA 4ZUXU 1KFXL 1PXVA 2R9FA 3H8CA 3WXGA 1YK8A 5K16A 4B55A 2G7YA 1IWDA 2BSZA 6PADA 2VHFA 1PPDA 3BPMA 8PCHA 5CHTA 2OP3A 3CBJA 3PBHA 1KXRA 3QT4A 4AXMA 2F1GA 1THEA 1BQIA 1VJVA 4N8WA 1CV8A 3GCBA 4MZOA 4CDEB 4DMYA 1HUCB 2E00A 5EGWA 1CB5A 3CBKA 3C9EA 4X6IA 1CS8A 3F75A 2ACTA 4PP1A 2YJCA 1NLJA 2B1NA 2XU5A 2AIMA 4OEMA 4YYQA 1QOLA 3V6CA 1VSNA 1NPZA 3IEJA 2YJBA 1EWPA 3TNXA 1YVBA 2CB5A 1F2CA 1ME4A 2DCCA 1GLOA 2VFBA 3WXEA 3IV2A 3KWBX 1AIMA 2G8JA 1NB3A 2P7UA 1U9WA 5JA7A 3H8BA 4CDDB 4I07A 1YK7A 3RVXA 1E2TA 1EF7A 2AU1A 2FQ9A 1PADA 2XU1A 2E03A 2R9NA 1STFE 1CPJA 2ATOA 1PPPA 4YYVA 2AUXA 3O0UA 4QRVA 1KHPA 1NQCA 1BY8A 4NV8A 1ICFA 4BS5A 2FTDA 3OVXA 2G6DA 4YYWA 4P6GA 3LTWA 2DC6A 3P5XA 5CVOB 4CDFB 1BP4A 1AU0A 2AYNA 3P5UA 1ZIVA 1GX3A 3KWZA 5FPWA 3BPFA 2BDZA 2GHUA 3ERVA 1ME3A 3OVZA 1KHQA 1PE6A 2FYEA 2DZZA 3IHPA 4BSQA 1NL6A 1YT7A 2DCDA 3KKUA 1AYVA 3B79A 4X6HA 1Y08A 4BPVA 1U9QX 3BC3A 4I04A 4W5BA 3QJ3A 2DCAA 1YALA 1U9VA 2IBIA 9PAPA 5CVNB 3MTNA 2E02A 2C0YA 4Q8HA 2YJ9A 1AU2A 4G54A 1POPA 4WA6A 1F2BA 2WBFX 1CSBB 3HHIA 3DF0A 2PADA 1W5RA 1GMYA 3USVA 3KW9A 2R9OA 3N3GA 4FJCA 3LFYA 2NQIA 1TL9A 3AI8A 3QSDA 1ZCMA 1QXPA 3BOWA 1AYWA 3I06A 2P86A 2FUDA 2HHNA 3RVVA 1CVZA 1BGOA 2GFOA 2NQDB 3KX1A 2PBHA 1FH0A 2AUZA 4YYUA 3PDFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DMX A;  2AVW A;  1S4V A;  1PPN A;  3OIS A;  1PBH A;  3D6S A;  3ZUA A;  3V6E A;  1PCI A;  2VHS A;  2E01 A;  2AS8 A;  3K9M A;  3P5V A;  2DCB A;  5CVM A;  1SNK A;  2HXZ A;  1DF0 A;  1K3B B;  1MEG A;  4YVA A;  3PNR A;  1XKG A;  4K7C A;  3F5V A;  2OUL A;  3O1G A;  2Y5B A;  2AYO A;  1MEM A;  2DC9 A;  3NHE A;  2HD5 A;  4YV8 A;  2OZ2 A;  3LXS A;  3OF8 A;  4AXL A;  1Q6K A;  2DJG B;  4RY2 A;  1MHW A;  1U5I A;  1GCB A;  4CDC B;  4YYS A;  2PNS A;  4X6J A;  2CIO A;  4W5C A;  2FRQ A;  1QDQ A;  4CZW A;  5PAD A;  4N4Z A;  3N4C A;  4BQV A;  3IOQ A;  2NQG A;  2FO5 A;  2H7J A;  2XU3 A;  1F2A A;  1A6R A;  2XU4 A;  1PIP A;  1KFU L;  2DC8 A;  1TLO A;  4W4U A;  4FK5 A;  1MS6 A;  3OF9 A;  3H6S A;  2IPP B;  2FT2 A;  2JQF R;  1AEC A;  3PW3 A;  3S3Q A;  2FRA A;  1EWM A;  3S3R A;  5EF4 A;  3HWN A;  4MSX A;  3WXF A;  4OEL A;  2O6X A;  3P5W A;  1CTE A;  3K8U A;  3MOR A;  4QBB A;  1AU3 A;  2BDL A;  2R6N A;  3H89 A;  7PCK A;  2DC7 A;  3I3T A;  4HWY A;  3U8E A;  1TU6 A;  2NQA A;  1X9Y A;  4PAD A;  4Q8G A;  2JQG R;  4MZS A;  3BCN A;  4QH6 A;  2HH5 A;  3CH3 X;  1JQP A;  1SP4 B;  1MDW A;  4PI3 A;  1O0E A;  3KSE A;  5F02 A;  1M6D A;  3N3K A;  1NB5 A;  1CQD A;  3KFQ A;  4QRX A;  2YJ2 A;  3K24 A;  2R9M A;  1GEC E;  1AYU A;  4QRG A;  1F29 A;  1Y4H A;  4PP2 E;  1U9X A;  1EWL A;  2G8E A;  5JH3 A;  5CHV A;  3M99 A;  2R9C A;  1MIR A;  4I05 A;  2Y6E A;  2DZY A;  4YYR A;  3CH2 X;  3RVW A;  2F7D A;  5J94 A;  3IMA A;  4BS6 A;  1DEU A;  4XR7 A;  2B1M A;  3MHH A;  2DJF B;  2ARY A;  4P6E A;  4XUI A;  5A24 A;  1ITO A;  3HD3 A;  1ATK A;  3MHS A;  2YJ8 A;  4KLB A;  2PRE A;  1CJL A;  3HHA A;  1AU4 A;  1PPO A;  3H7D A;  1EWO A;  4N79 A;  2P0R A;  3IUT A;  4FIP A;  3BWK A;  3E1Z B;  1QMY A;  4ZUX U;  1KFX L;  1PXV A;  2R9F A;  3H8C A;  3WXG A;  1YK8 A;  5K16 A;  2G7Y A;  1IWD A;  6PAD A;  2VHF A;  1PPD A;  3BPM A;  8PCH A;  5CHT A;  2OP3 A;  3CBJ A;  3PBH A;  1KXR A;  3QT4 A;  4AXM A;  2F1G A;  1THE A;  1BQI A;  1VJV A;  4N8W A;  1CV8 A;  3GCB A;  4MZO A;  4CDE B;  4DMY A;  1HUC B;  2E00 A;  5EGW A;  1CB5 A;  3CBK A;  3C9E A;  4X6I A;  1CS8 A;  3F75 A;  2ACT A;  4PP1 A;  2YJC A;  1NLJ A;  2B1N A;  2XU5 A;  2AIM A;  4OEM A;  4YYQ A;  1QOL A;  3V6C A;  1VSN A;  1NPZ A;  3IEJ A;  2YJB A;  1EWP A;  3TNX A;  1YVB A;  2CB5 A;  1F2C A;  1ME4 A;  2DCC A;  1GLO A;  3WXE A;  3IV2 A;  3KWB X;  1AIM A;  2G8J A;  1NB3 A;  2P7U A;  1U9W A;  5JA7 A;  3H8B A;  4CDD B;  4I07 A;  1YK7 A;  3RVX A;  1EF7 A;  2AU1 A;  2FQ9 A;  1PAD A;  2XU1 A;  2E03 A;  2R9N A;  1STF E;  1CPJ A;  2ATO A;  1PPP A;  4YYV A;  2AUX A;  3O0U A;  4QRV A;  1KHP A;  1NQC A;  1BY8 A;  1ICF A;  4BS5 A;  2FTD A;  3OVX A;  2G6D A;  4YYW A;  4P6G A;  2DC6 A;  3P5X A;  5CVO B;  4CDF B;  1BP4 A;  1AU0 A;  2AYN A;  3P5U A;  1ZIV A;  3KWZ A;  5FPW A;  3BPF A;  2BDZ A;  2GHU A;  3ERV A;  1ME3 A;  3OVZ A;  1KHQ A;  1PE6 A;  2FYE A;  2DZZ A;  3IHP A;  4BSQ A;  1NL6 A;  1YT7 A;  2DCD A;  3KKU A;  1AYV A;  3B79 A;  4X6H A;  1Y08 A;  4BPV A;  1U9Q X;  3BC3 A;  4I04 A;  4W5B A;  3QJ3 A;  2DCA A;  1YAL A;  1U9V A;  2IBI A;  9PAP A;  5CVN B;  3MTN A;  2E02 A;  2C0Y A;  4Q8H A;  2YJ9 A;  1AU2 A;  4G54 A;  1POP A;  4WA6 A;  1F2B A;  2WBF X;  1CSB B;  3HHI A;  3DF0 A;  2PAD A;  1GMY A;  3USV A;  3KW9 A;  2R9O A;  3N3G A;  4FJC A;  3LFY A;  2NQI A;  1TL9 A;  3AI8 A;  3QSD A;  1ZCM A;  1QXP A;  3BOW A;  1AYW A;  3I06 A;  2P86 A;  2FUD A;  2HHN A;  3RVV A;  1CVZ A;  1BGO A;  2GFO A;  2NQD B;  3KX1 A;  2PBH A;  1FH0 A;  2AUZ A;  4YYU A;  3PDF A; 
#chains in the Genus database with same CATH topology
 4DMX A;  2AVW A;  4PT5 A;  1S4V A;  1PPN A;  3OIS A;  1PBH A;  3D6S A;  4RKX A;  3ZUA A;  3V6E A;  1PCI A;  2VHS A;  2E01 A;  2AS8 A;  3K9M A;  3P5V A;  2DCB A;  5CVM A;  1SNK A;  2HXZ A;  4OW0 A;  1DF0 A;  1K3B B;  1MEG A;  4YVA A;  3PNR A;  1XKG A;  4K7C A;  3F5V A;  2OUL A;  3O1G A;  2Y5B A;  2AYO A;  1MEM A;  2DC9 A;  3NHE A;  2HD5 A;  4YV8 A;  2OZ2 A;  3LXS A;  3OF8 A;  4AXL A;  4GUA A;  1Q6K A;  4BOP A;  2DJG B;  4RY2 A;  3PHU A;  1MHW A;  2HWK A;  1U5I A;  1GCB A;  3O65 A;  4CDC B;  4YYS A;  2PNS A;  4X6J A;  5E6J A;  2CIO A;  4W5C A;  2FRQ A;  1QDQ A;  4BOZ A;  4CZW A;  5PAD A;  4N4Z A;  3N4C A;  3PT2 A;  4BQV A;  3IOQ A;  2NQG A;  2FO5 A;  2H7J A;  2XU3 A;  1F2A A;  2JRI A;  1A6R A;  2XU4 A;  1PIP A;  2BU3 A;  1KFU L;  2DC8 A;  1TLO A;  4W4U A;  4FK5 A;  1MS6 A;  3OF9 A;  3H6S A;  2IPP B;  2FT2 A;  2JQF R;  1AEC A;  3PW3 A;  3S3Q A;  3BY4 A;  2FRA A;  1EWM A;  3S3R A;  5EF4 A;  3HWN A;  5KO3 A;  4HXD B;  4MSX A;  3WXF A;  4OEL A;  4OVZ B;  2O6X A;  3P5W A;  1CTE A;  3K8U A;  3MOR A;  4QBB A;  1AU3 A;  2BDL A;  2R6N A;  3H89 A;  2DOS A;  7PCK A;  2DC7 A;  3I3T A;  2FE8 A;  4HWY A;  1TU6 A;  2NQA A;  3U8E A;  4IP3 A;  4M0W A;  1X9Y A;  4PAD A;  4Q8G A;  2JQG R;  4MZS A;  3BCN A;  4QH6 A;  2HH5 A;  3CH3 X;  1JQP A;  1SP4 B;  1MDW A;  3MP2 A;  4PI3 A;  5JZE A;  1O0E A;  3KSE A;  5F02 A;  1M6D A;  3N3K A;  1NB5 A;  1CQD A;  3KFQ A;  4QRX A;  2YJ2 A;  3K24 A;  2R9M A;  1GEC E;  1AYU A;  4QRG A;  3IFU A;  3B21 A;  1F29 A;  1Y4H A;  4PP2 E;  1U9X A;  1EWL A;  2G8E A;  5JH3 A;  5CHV A;  4IUM A;  3M99 A;  4MM3 B;  2R9C A;  3PHX A;  3MTV A;  1MIR A;  4I05 A;  4RF0 A;  2BTW B;  2Y6E A;  2DZY A;  4YYR A;  3CH2 X;  3RVW A;  2F7D A;  5J94 A;  3IMA A;  4BS6 A;  1DEU A;  4XR7 A;  4A5U A;  2B1M A;  3MHH A;  2DJF B;  2ARY A;  4P6E A;  3PRP A;  4XUI A;  5A24 A;  1ITO A;  3HD3 A;  1ATK A;  3MHS A;  2YJ8 A;  4KLB A;  2PRE A;  1CJL A;  3HHA A;  1AU4 A;  1PPO A;  3H7D A;  1EWO A;  4N79 A;  2P0R A;  3IUT A;  4FIP A;  3BWK A;  3E1Z B;  1QMY A;  4ZUX U;  1KFX L;  1PXV A;  2R9F A;  4XZX A;  3H8C A;  2J7Q C;  3WXG A;  4WUR A;  1YK8 A;  5K16 A;  2UZJ A;  2G7Y A;  1IWD A;  6PAD A;  2VHF A;  1PPD A;  3BPM A;  8PCH A;  5CHT A;  2Z84 A;  2OP3 A;  3CBJ A;  2AGA A;  3PBH A;  1KXR A;  4RNA A;  3QT4 A;  4AXM A;  2F1G A;  1THE A;  1BQI A;  1VJV A;  4N8W A;  1CV8 A;  3GCB A;  4MZO A;  4BOQ A;  4CDE B;  4DMY A;  1HUC B;  2E00 A;  3W31 A;  3E9S A;  5EGW A;  1CB5 A;  3CBK A;  3C9E A;  4X6I A;  1CS8 A;  3F75 A;  2ACT A;  4PP1 A;  2YJC A;  1NLJ A;  4OVZ A;  5EZQ A;  2B1N A;  2XU5 A;  2AIM A;  4OEM A;  4YYQ A;  1QOL A;  3V6C A;  1VSN A;  1NPZ A;  2J7Q A;  3IEJ A;  2YJB A;  1EWP A;  3TNX A;  1YVB A;  2CB5 A;  1F2C A;  1ME4 A;  2DCC A;  1GLO A;  3WXE A;  3IV2 A;  1YZB A;  3KWB X;  1AIM A;  2G8J A;  4BOS A;  4D8E A;  1NB3 A;  3BB7 A;  2P7U A;  1U9W A;  5JA7 A;  3H8B A;  4CDD B;  4I07 A;  3ZNH A;  1YK7 A;  3MJ5 A;  3RVX A;  4D8I A;  1EF7 A;  2AU1 A;  2FQ9 A;  3TRK A;  1PAD A;  2XU1 A;  3PHW A;  2E03 A;  1UKF A;  2R9N A;  1STF E;  1CPJ A;  2ATO A;  1PPP A;  4YYV A;  3PRM A;  2AUX A;  3O0U A;  4QRV A;  1KHP A;  2JTC A;  1NQC A;  1BY8 A;  2BTW A;  1ICF A;  4BS5 A;  2FTD A;  3OVX A;  2G6D A;  4YYW A;  5EZS A;  4ZTB A;  4P6G A;  2DC6 A;  3P5X A;  5CVO B;  4CDF B;  1BP4 A;  1AU0 A;  2AYN A;  3P5U A;  3W30 A;  1ZIV A;  3KWZ A;  5FPW A;  3BPF A;  2BDZ A;  3RNV A;  2GHU A;  3ERV A;  1ME3 A;  3OVZ A;  1KHQ A;  1PE6 A;  2FYE A;  3TMP A;  2DZZ A;  3IHP A;  4BSQ A;  1NL6 A;  1YT7 A;  4D8B A;  3PSE A;  2DCD A;  3KKU A;  1AYV A;  3B79 A;  4X6H A;  4RF1 A;  1Y08 A;  4BPV A;  1U9Q X;  3BC3 A;  4I04 A;  4W5B A;  3QJ3 A;  2DCA A;  1YAL A;  1U9V A;  3BBA A;  2IBI A;  9PAP A;  5CVN B;  3MTN A;  2E02 A;  2C0Y A;  4Q8H A;  2YJ9 A;  1AU2 A;  4REZ A;  4G54 A;  1POP A;  4WA6 A;  1F2B A;  2WBF X;  4MI7 A;  1CSB B;  3HHI A;  3OQC A;  3DF0 A;  2PAD A;  1PVJ A;  1GMY A;  3USV A;  3KW9 A;  2R9O A;  3N3G A;  4FJC A;  3LFY A;  2NQI A;  1TL9 A;  3AI8 A;  3QSD A;  1ZCM A;  1QXP A;  3BOW A;  3C0R A;  1AYW A;  3I06 A;  4BOU A;  2P86 A;  2FUD A;  2HHN A;  1DKI A;  4P16 A;  4R3D A;  3RVV A;  1CVZ A;  1BGO A;  2GFO A;  2NQD B;  3KX1 A;  2PBH A;  1FH0 A;  2AUZ A;  4YYU A;  3PDF A; 
#chains in the Genus database with same CATH homology
 4DMX A;  2AVW A;  1S4V A;  1W4T A;  1PPN A;  3OIS A;  1PBH A;  3D6S A;  3ZUA A;  3V6E A;  1PCI A;  2VHS A;  2E01 A;  2AS8 A;  3K9M A;  3P5V A;  2DCB A;  5CVM A;  1SNK A;  2HXZ A;  1DF0 A;  1K3B B;  4BGF A;  1MEG A;  4YVA A;  3PNR A;  1XKG A;  4K7C A;  3F5V A;  2OUL A;  3O1G A;  2Y5B A;  4NV7 A;  2AYO A;  1MEM A;  2DC9 A;  3NHE A;  2HD5 A;  4YV8 A;  2OZ2 A;  3LXS A;  3OF8 A;  4AXL A;  1Q6K A;  2DJG B;  4RY2 A;  1MHW A;  1U5I A;  1GCB A;  4CDC B;  4YYS A;  2PNS A;  4X6J A;  2CIO A;  4W5C A;  2FRQ A;  1QDQ A;  4CZW A;  5PAD A;  4N4Z A;  3N4C A;  4BQV A;  3IOQ A;  2NQG A;  2FO5 A;  2H7J A;  2XU3 A;  1F2A A;  1A6R A;  2XU4 A;  1PIP A;  4C5P A;  1KFU L;  2DC8 A;  1TLO A;  4W4U A;  4FK5 A;  1MS6 A;  3OF9 A;  3H6S A;  2IPP B;  2FT2 A;  2JQF R;  1AEC A;  3PW3 A;  3S3Q A;  2FRA A;  1EWM A;  3S3R A;  5EF4 A;  3HWN A;  4MSX A;  3WXF A;  4OEL A;  2O6X A;  3P5W A;  1CTE A;  3K8U A;  3MOR A;  4QBB A;  1AU3 A;  2BDL A;  2R6N A;  3H89 A;  7PCK A;  2DC7 A;  3I3T A;  4HWY A;  3U8E A;  1TU6 A;  2NQA A;  1X9Y A;  4PAD A;  4Q8G A;  2JQG R;  4MZS A;  3BCN A;  4QH6 A;  2HH5 A;  3CH3 X;  1JQP A;  1SP4 B;  1MDW A;  4PI3 A;  1O0E A;  3KSE A;  5F02 A;  1M6D A;  3N3K A;  1NB5 A;  1CQD A;  3KFQ A;  4QRX A;  2YJ2 A;  3K24 A;  2R9M A;  1GEC E;  1AYU A;  4QRG A;  1F29 A;  2VFC A;  1Y4H A;  4PP2 E;  1U9X A;  1EWL A;  2G8E A;  5JH3 A;  5CHV A;  3M99 A;  2R9C A;  1MIR A;  4I05 A;  2Y6E A;  2DZY A;  4YYR A;  3CH2 X;  3RVW A;  2F7D A;  5J94 A;  3D9W A;  1W6F A;  3IMA A;  4BS6 A;  1DEU A;  4XR7 A;  2B1M A;  3MHH A;  2DJF B;  2ARY A;  4P6E A;  4XUI A;  5A24 A;  1ITO A;  3HD3 A;  1ATK A;  3MHS A;  4GUZ A;  2YJ8 A;  4KLB A;  2PRE A;  1CJL A;  3HHA A;  1AU4 A;  1PPO A;  3H7D A;  1EWO A;  4N79 A;  2P0R A;  3IUT A;  4FIP A;  3BWK A;  3E1Z B;  1QMY A;  4ZUX U;  1KFX L;  1PXV A;  2R9F A;  3H8C A;  3WXG A;  1YK8 A;  5K16 A;  4B55 A;  2G7Y A;  1IWD A;  2BSZ A;  6PAD A;  2VHF A;  1PPD A;  3BPM A;  8PCH A;  5CHT A;  2OP3 A;  3CBJ A;  3PBH A;  1KXR A;  3QT4 A;  4AXM A;  2F1G A;  1THE A;  1BQI A;  1VJV A;  4N8W A;  1CV8 A;  3GCB A;  4MZO A;  4CDE B;  4DMY A;  1HUC B;  2E00 A;  5EGW A;  1CB5 A;  3CBK A;  3C9E A;  4X6I A;  1CS8 A;  3F75 A;  2ACT A;  4PP1 A;  2YJC A;  1NLJ A;  2B1N A;  2XU5 A;  2AIM A;  4OEM A;  4YYQ A;  1QOL A;  3V6C A;  1VSN A;  1NPZ A;  3IEJ A;  2YJB A;  1EWP A;  3TNX A;  1YVB A;  2CB5 A;  1F2C A;  1ME4 A;  2DCC A;  1GLO A;  2VFB A;  3WXE A;  3IV2 A;  3KWB X;  1AIM A;  2G8J A;  1NB3 A;  2P7U A;  1U9W A;  5JA7 A;  3H8B A;  4CDD B;  4I07 A;  1YK7 A;  3RVX A;  1E2T A;  1EF7 A;  2AU1 A;  2FQ9 A;  1PAD A;  2XU1 A;  2E03 A;  2R9N A;  1STF E;  1CPJ A;  2ATO A;  1PPP A;  4YYV A;  2AUX A;  3O0U A;  4QRV A;  1KHP A;  1NQC A;  1BY8 A;  4NV8 A;  1ICF A;  4BS5 A;  2FTD A;  3OVX A;  2G6D A;  4YYW A;  4P6G A;  3LTW A;  2DC6 A;  3P5X A;  5CVO B;  4CDF B;  1BP4 A;  1AU0 A;  2AYN A;  3P5U A;  1ZIV A;  1GX3 A;  3KWZ A;  5FPW A;  3BPF A;  2BDZ A;  2GHU A;  3ERV A;  1ME3 A;  3OVZ A;  1KHQ A;  1PE6 A;  2FYE A;  2DZZ A;  3IHP A;  4BSQ A;  1NL6 A;  1YT7 A;  2DCD A;  3KKU A;  1AYV A;  3B79 A;  4X6H A;  1Y08 A;  4BPV A;  1U9Q X;  3BC3 A;  4I04 A;  4W5B A;  3QJ3 A;  2DCA A;  1YAL A;  1U9V A;  2IBI A;  9PAP A;  5CVN B;  3MTN A;  2E02 A;  2C0Y A;  4Q8H A;  2YJ9 A;  1AU2 A;  4G54 A;  1POP A;  4WA6 A;  1F2B A;  2WBF X;  1CSB B;  3HHI A;  3DF0 A;  2PAD A;  1W5R A;  1GMY A;  3USV A;  3KW9 A;  2R9O A;  3N3G A;  4FJC A;  3LFY A;  2NQI A;  1TL9 A;  3AI8 A;  3QSD A;  1ZCM A;  1QXP A;  3BOW A;  1AYW A;  3I06 A;  2P86 A;  2FUD A;  2HHN A;  3RVV A;  1CVZ A;  1BGO A;  2GFO A;  2NQD B;  3KX1 A;  2PBH A;  1FH0 A;  2AUZ A;  4YYU A;  3PDF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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