1ME4A

High resolution crystal structure analysis of cruzain non-covalently bound to a hydroxymethyl ketone inhibitor (i)
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
215
structure length
215
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Reversible Ketone-based Inhibitors of the Cysteine Protease Cruzain
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords CRUZIPAIN
total genus 62
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2002-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1me4A00
3IV2A 4DMXA 2GFOA 1PBHA 3BCNA 2ATOA 1GMYA 1PADA 4AXMA 1YALA 2DZYA 3WXFA 3PNRA 5CHTA 1CPJA 1Y4HA 4YYQA 2Y5BA 3IMAA 4QRXA 4I07A 1KFUL 2OULA 1QDQA 1YVBA 4X6JA 1PXVA 3HWNA 1GCBA 1CS8A 4N4ZA 1PCIA 2VHSA 2DJFB 2OZ2A 4BPVA 1GECE 1S4VA 2ARYA 3KSEA 5EF4A 3OF8A 1TL9A 3DF0A 3KKUA 3P5VA 3WXEA 3BWKA 4BS6A 1FH0A 1QMYA 5A24A 3PBHA 5K16A 4FIPA 4X6IA 3KWZA 1A6RA 3WXGA 2E02A 1U9VA 1MEMA 1AECA 2DCAA 2DJGB 2CB5A 1AYUA 4QRGA 1AYWA 3ZUAA 2XU4A 2DC9A 2OP3A 3KFQA 3CBJA 1KFXL 3IOQA 2DC6A 5CVNB 2R9FA 4QRVA 4MSXA 1YT7A 1MEGA 1NLJA 2H7JA 3P5XA 1VJVA 4W5BA 1U9XA 2FRAA 4OELA 3BC3A 3RVXA 2XU3A 2HD5A 4MZOA 2PREA 2AVWA 4CZWA 1K3BB 4RY2A 4FJCA 1EWPA 1CVZA 2F1GA 2E03A 3N3KA 2YJCA 1PPPA 4QBBA 3S3RA 2R9CA 5CVMA 2DC8A 3KWBX 4YYRA 2FTDA 2G7YA 3LXSA 3QSDA 1ATKA 1ME3A 3HD3A 4G54A 4N8WA 2P7UA 4W4UA 5CHVA 1NL6A 2G6DA 4WA6A 3H8BA 2AU1A 2VHFA 3PDFA 4DMYA 2P86A 3F5VA 1DEUA 1HUCB 4P6EA 4OEMA 1DF0A 2FQ9A 3B79A 4CDDB 5JH3A 5CVOB 2JQFR 2C0YA 4N79A 3OVXA 2XU5A 3P5UA 4YV8A 3O1GA 3BPMA 2DCDA 2NQIA 3TNXA 3OVZA 4MZSA 1U9WA 1ZCMA 3F75A 1PPOA 3P5WA 4K7CA 2HHNA 4BQVA 1F29A 1KHPA 3C9EA 5F02A 1KXRA 3HHIA 3QT4A 3CH3X 2PADA 2GHUA 1AYVA 2NQAA 2YJ9A 2HH5A 3GCBA 3MTNA 1F2CA 3OISA 2CIOA 2FO5A 3MHHA 2NQDB 4I05A 2R6NA 2R9MA 1NB5A 2FUDA 4AXLA 4XUIA 4PI3A 1M6DA 4BS5A 2B1MA 3S3QA 1EWMA 2HXZA 4BSQA 4I04A 2FT2A 1AU0A 1NB3A 4CDEB 1U5IA 1PE6A 2G8JA 1NPZA 3N3GA 1XKGA 3O0UA 2PNSA 1POPA 1STFE 3ERVA 2Y6EA 3I3TA 1BGOA 4Q8GA 3BOWA 1CJLA 1SNKA 1BY8A 1YK7A 1AU4A 1TLOA 5EGWA 2O6XA 3IHPA 2F7DA 4YVAA 1JQPA 4P6GA 2R9OA 3AI8A 5FPWA 1F2AA 1Y08A 2B1NA 1AU3A 3KW9A 1NQCA 1TU6A 1Q6KA 1PPNA 4Q8HA 2DCCA 4CDCB 5JA7A 1PPDA 2FRQA 7PCKA 3N4CA 4ZUXU 2ACTA 3IUTA 4PP1A 2AYNA 2YJBA 2PBHA 3RVWA 1U9QX 3OF9A 4PP2E 1PIPA 2G8EA 3K8UA 3USVA 1AIMA 3D6SA 4YYUA 2AIMA 2R9NA 3H6SA 1QXPA 3CH2X 4YYSA 4HWYA 1KHQA 3V6CA 9PAPA 1BQIA 4KLBA 1ITOA 4YYVA 1BP4A 3NHEA 3K9MA 2E01A 3CBKA 3MHSA 1O0EA 1MDWA 1THEA 2DCBA 2XU1A 4QH6A 2AYOA 1CQDA 2BDZA 1AU2A 5PADA 1EWOA 3QJ3A 4YYWA 1X9YA 2NQGA 2FYEA 2IBIA 1SP4B 2P0RA 3RVVA 1EF7A 3H7DA 2BDLA 3MORA 2AS8A 4W5CA 2AUZA 5J94A 1ICFA 2IPPB 2YJ8A 3H89A 1MHWA 8PCHA 1ZIVA 2DC7A 1YK8A 3U8EA 2DZZA 3BPFA 3PW3A 1CSBB 3KX1A 1CV8A 1QOLA 2JQGR 6PADA 1EWLA 2WBFX 1GLOA 3M99A 1ME4A 3IEJA 1MIRA 2E00A 3LFYA 2AUXA 1IWDA 4FK5A 3HHAA 1VSNA 3E1ZB 1CTEA 1F2BA 3K24A 4CDFB 3H8CA 4X6HA 3V6EA 1CB5A 2YJ2A 3I06A 4XR7A 4PADA 1MS6A
chains in the Genus database with same CATH superfamily
3IV2A 3IFUA 2J7QC 2AGAA 4DMXA 2GFOA 1PBHA 3BCNA 2ATOA 1GMYA 1PADA 4AXMA 1YALA 2DZYA 3WXFA 3PNRA 5CHTA 1CPJA 1Y4HA 4YYQA 2Y5BA 3IMAA 4QRXA 4I07A 1KFUL 2OULA 1QDQA 1YVBA 4X6JA 1PXVA 3HWNA 1GCBA 1CS8A 2BU3A 4N4ZA 1PCIA 2VHSA 2DJFB 2OZ2A 4BPVA 1GECE 1S4VA 2ARYA 1YZBA 3KSEA 5EF4A 3OF8A 1TL9A 3DF0A 3KKUA 3P5VA 3WXEA 3BWKA 4BS6A 1FH0A 1QMYA 5A24A 3PBHA 5K16A 4FIPA 4X6IA 3KWZA 1A6RA 3WXGA 2E02A 1U9VA 1UKFA 1MEMA 1AECA 2DCAA 2DJGB 2CB5A 1AYUA 3C0RA 4QRGA 1AYWA 3ZUAA 2XU4A 2DC9A 2OP3A 3KFQA 3CBJA 4BOSA 1KFXL 3IOQA 2DC6A 5CVNB 2R9FA 4QRVA 4MSXA 4A5UA 1YT7A 1MEGA 1NLJA 2H7JA 3P5XA 5JZEA 1VJVA 4W5BA 1U9XA 2FRAA 3PRMA 4OELA 3PT2A 4XZXA 3BC3A 3RVXA 4BOQA 2XU3A 2HD5A 4MZOA 3B21A 2PREA 2AVWA 1DKIA 4ZTBA 4CZWA 1K3BB 3TMPA 4RY2A 4FJCA 1EWPA 2FE8A 1CVZA 2F1GA 4BOPA 2E03A 3N3KA 2YJCA 4RNAA 1PPPA 4QBBA 4M0WA 3S3RA 2R9CA 4BOUA 5CVMA 2DC8A 3BY4A 3KWBX 4YYRA 2FTDA 2G7YA 3LXSA 3QSDA 1ATKA 1ME3A 3HD3A 4G54A 4N8WA 2P7UA 4W4UA 5CHVA 1NL6A 2G6DA 4WA6A 3TRKA 3H8BA 2AU1A 5KO3A 2VHFA 4OVZB 3PDFA 4GUAA 4DMYA 3W31A 2P86A 3F5VA 1DEUA 1HUCB 4P6EA 4OEMA 4REZA 1DF0A 2FQ9A 3B79A 4CDDB 2JTCA 5JH3A 4RF1A 5CVOB 2JQFR 2C0YA 4N79A 3OVXA 2JRIA 2XU5A 3P5UA 4YV8A 3O1GA 3PRPA 3BPMA 2DCDA 2NQIA 3TNXA 3OVZA 4MZSA 1U9WA 1ZCMA 3F75A 1PPOA 4BOZA 3P5WA 4K7CA 2HHNA 4BQVA 1F29A 1KHPA 3C9EA 5F02A 1KXRA 3HHIA 3QT4A 5EZSA 3CH3X 2PADA 2GHUA 1AYVA 2NQAA 2YJ9A 2HH5A 3GCBA 3MTNA 1F2CA 3OISA 2CIOA 2FO5A 3MHHA 2NQDB 4I05A 2R6NA 2R9MA 1NB5A 2FUDA 4AXLA 3MJ5A 4XUIA 4PI3A 1M6DA 4HXDB 4BS5A 4RF0A 2B1MA 3S3QA 5E6JA 1EWMA 2HXZA 4BSQA 4I04A 2FT2A 1AU0A 1NB3A 4CDEB 1U5IA 1PE6A 2G8JA 1NPZA 3N3GA 1XKGA 3PSEA 3O0UA 2PNSA 1POPA 1STFE 3ERVA 4IUMA 2Y6EA 3I3TA 1BGOA 4Q8GA 3BOWA 1CJLA 3ZNHA 3PHUA 1SNKA 1BY8A 1YK7A 3MP2A 2UZJA 3PHWA 1AU4A 1TLOA 5EGWA 2O6XA 3IHPA 4PT5A 4MI7A 2F7DA 4YVAA 1JQPA 4P6GA 2R9OA 3AI8A 5FPWA 1F2AA 1Y08A 4D8IA 2B1NA 1AU3A 4D8EA 3KW9A 1NQCA 1TU6A 4MM3B 1Q6KA 1PPNA 3O65A 4Q8HA 2DCCA 2BTWA 4CDCB 5JA7A 1PPDA 2FRQA 7PCKA 3N4CA 4ZUXU 2ACTA 3IUTA 4RKXA 4PP1A 2AYNA 2YJBA 2PBHA 3RVWA 1U9QX 3OF9A 4PP2E 1PVJA 1PIPA 4OW0A 2G8EA 3K8UA 3USVA 1AIMA 4IP3A 2DOSA 3D6SA 4P16A 4YYUA 2AIMA 2R9NA 3H6SA 1QXPA 3CH2X 4YYSA 4HWYA 1KHQA 3V6CA 9PAPA 3RNVA 1BQIA 2J7QA 4KLBA 1ITOA 4YYVA 1BP4A 3NHEA 3K9MA 2E01A 3CBKA 3MHSA 1O0EA 1MDWA 1THEA 2DCBA 2XU1A 4QH6A 2AYOA 1CQDA 2BDZA 1AU2A 4WURA 5PADA 1EWOA 3QJ3A 4YYWA 1X9YA 2BTWB 2NQGA 2FYEA 2IBIA 1SP4B 3BB7A 2P0RA 3RVVA 1EF7A 3BBAA 3H7DA 2BDLA 3MORA 2AS8A 4W5CA 2AUZA 5J94A 5EZQA 1ICFA 2Z84A 2IPPB 2YJ8A 3H89A 4D8BA 3E9SA 1MHWA 3OQCA 8PCHA 1ZIVA 2DC7A 1YK8A 3U8EA 2DZZA 3BPFA 3PW3A 4OVZA 1CSBB 3KX1A 1CV8A 1QOLA 2JQGR 6PADA 1EWLA 3MTVA 2WBFX 1GLOA 3M99A 1ME4A 3IEJA 1MIRA 3PHXA 2E00A 3LFYA 2AUXA 1IWDA 4FK5A 3HHAA 1VSNA 2HWKA 3E1ZB 1CTEA 1F2BA 3K24A 4CDFB 3W30A 3H8CA 4X6HA 3V6EA 1CB5A 2YJ2A 4R3DA 3I06A 4XR7A 4PADA 1MS6A
chains in the Genus database with same CATH topology
3IV2A 4DMXA 2GFOA 1PBHA 3BCNA 2ATOA 1GMYA 1PADA 4AXMA 1YALA 2DZYA 3WXFA 3PNRA 5CHTA 1CPJA 1Y4HA 4YYQA 2Y5BA 3IMAA 4QRXA 4I07A 1KFUL 2OULA 1QDQA 1YVBA 4X6JA 1PXVA 4GUZA 3HWNA 4NV7A 1GCBA 1CS8A 4N4ZA 1PCIA 2VHSA 2DJFB 2OZ2A 4BPVA 1GECE 1S4VA 2ARYA 3KSEA 5EF4A 3OF8A 1TL9A 3DF0A 3KKUA 3P5VA 3WXEA 3BWKA 4BS6A 1FH0A 1QMYA 5A24A 3PBHA 5K16A 4FIPA 4X6IA 3KWZA 1A6RA 3WXGA 2E02A 1U9VA 3LTWA 1W5RA 1MEMA 1AECA 2DCAA 2DJGB 2CB5A 1AYUA 1GX3A 4QRGA 1AYWA 3ZUAA 2XU4A 2DC9A 2OP3A 3KFQA 3CBJA 1KFXL 3IOQA 2DC6A 5CVNB 2R9FA 2VFCA 4QRVA 4MSXA 1E2TA 1YT7A 1MEGA 1NLJA 2H7JA 3P5XA 1VJVA 4W5BA 1U9XA 2FRAA 4OELA 3BC3A 3RVXA 2XU3A 2HD5A 4MZOA 2PREA 2AVWA 4CZWA 1K3BB 4RY2A 4FJCA 1W6FA 1EWPA 4C5PA 1CVZA 2F1GA 2E03A 3N3KA 2YJCA 1PPPA 4QBBA 3S3RA 2R9CA 5CVMA 2DC8A 3KWBX 4YYRA 2FTDA 2G7YA 3LXSA 3QSDA 1ATKA 1ME3A 3HD3A 4G54A 4N8WA 2P7UA 4W4UA 5CHVA 1NL6A 2G6DA 4WA6A 3H8BA 2AU1A 2VHFA 3PDFA 4DMYA 2P86A 3F5VA 1DEUA 1HUCB 4P6EA 4OEMA 1DF0A 2FQ9A 3B79A 4NV8A 4CDDB 5JH3A 5CVOB 2JQFR 2C0YA 4N79A 3OVXA 2VFBA 2XU5A 3P5UA 4YV8A 3O1GA 3BPMA 3D9WA 2DCDA 2NQIA 3TNXA 3OVZA 4MZSA 1U9WA 1ZCMA 3F75A 1PPOA 3P5WA 4K7CA 2HHNA 4BQVA 1F29A 1KHPA 3C9EA 5F02A 1KXRA 3HHIA 3QT4A 3CH3X 2PADA 2GHUA 1AYVA 2NQAA 2YJ9A 2HH5A 3GCBA 3MTNA 1F2CA 3OISA 2CIOA 2FO5A 3MHHA 2NQDB 4I05A 2R6NA 2R9MA 1NB5A 2FUDA 4AXLA 4XUIA 4PI3A 1M6DA 4BS5A 2B1MA 3S3QA 1EWMA 2HXZA 4BSQA 4I04A 2FT2A 1AU0A 1NB3A 4CDEB 1U5IA 1PE6A 2G8JA 1NPZA 3N3GA 1XKGA 3O0UA 2PNSA 1POPA 1STFE 3ERVA 2Y6EA 1W4TA 3I3TA 1BGOA 4Q8GA 3BOWA 1CJLA 1SNKA 1BY8A 1YK7A 4B55A 1AU4A 1TLOA 5EGWA 2O6XA 3IHPA 2F7DA 4YVAA 1JQPA 4P6GA 2R9OA 3AI8A 5FPWA 1F2AA 1Y08A 2B1NA 1AU3A 3KW9A 1NQCA 1TU6A 1Q6KA 1PPNA 4Q8HA 2DCCA 4CDCB 5JA7A 1PPDA 2FRQA 7PCKA 3N4CA 4ZUXU 2ACTA 3IUTA 4PP1A 2AYNA 2YJBA 2PBHA 3RVWA 1U9QX 3OF9A 4PP2E 1PIPA 2G8EA 3K8UA 3USVA 1AIMA 3D6SA 4YYUA 2AIMA 2R9NA 3H6SA 1QXPA 3CH2X 4YYSA 4HWYA 1KHQA 3V6CA 9PAPA 1BQIA 4KLBA 1ITOA 4YYVA 1BP4A 3NHEA 3K9MA 2E01A 3CBKA 3MHSA 1O0EA 1MDWA 1THEA 2DCBA 2XU1A 4QH6A 2AYOA 1CQDA 2BDZA 1AU2A 5PADA 1EWOA 3QJ3A 4YYWA 1X9YA 2NQGA 2FYEA 4BGFA 2IBIA 1SP4B 2P0RA 3RVVA 1EF7A 3H7DA 2BDLA 3MORA 2AS8A 4W5CA 2AUZA 5J94A 1ICFA 2IPPB 2YJ8A 3H89A 1MHWA 8PCHA 1ZIVA 2DC7A 1YK8A 3U8EA 2DZZA 3BPFA 3PW3A 1CSBB 3KX1A 1CV8A 1QOLA 2JQGR 6PADA 1EWLA 2WBFX 1GLOA 3M99A 1ME4A 3IEJA 1MIRA 2BSZA 2E00A 3LFYA 2AUXA 1IWDA 4FK5A 3HHAA 1VSNA 3E1ZB 1CTEA 1F2BA 3K24A 4CDFB 3H8CA 4X6HA 3V6EA 1CB5A 2YJ2A 3I06A 4XR7A 4PADA 1MS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IV2 A;  4DMX A;  2GFO A;  1PBH A;  3BCN A;  2ATO A;  1GMY A;  1PAD A;  4AXM A;  1YAL A;  2DZY A;  3WXF A;  3PNR A;  5CHT A;  1CPJ A;  1Y4H A;  4YYQ A;  2Y5B A;  3IMA A;  4QRX A;  4I07 A;  1KFU L;  2OUL A;  1QDQ A;  1YVB A;  4X6J A;  1PXV A;  3HWN A;  1GCB A;  1CS8 A;  4N4Z A;  1PCI A;  2VHS A;  2DJF B;  2OZ2 A;  4BPV A;  1GEC E;  1S4V A;  2ARY A;  3KSE A;  5EF4 A;  3OF8 A;  1TL9 A;  3DF0 A;  3KKU A;  3P5V A;  3WXE A;  3BWK A;  4BS6 A;  1FH0 A;  1QMY A;  5A24 A;  3PBH A;  5K16 A;  4FIP A;  4X6I A;  3KWZ A;  1A6R A;  3WXG A;  2E02 A;  1U9V A;  1MEM A;  1AEC A;  2DCA A;  2DJG B;  2CB5 A;  1AYU A;  4QRG A;  1AYW A;  3ZUA A;  2XU4 A;  2DC9 A;  2OP3 A;  3KFQ A;  3CBJ A;  1KFX L;  3IOQ A;  2DC6 A;  5CVN B;  2R9F A;  4QRV A;  4MSX A;  1YT7 A;  1MEG A;  1NLJ A;  2H7J A;  3P5X A;  1VJV A;  4W5B A;  1U9X A;  2FRA A;  4OEL A;  3BC3 A;  3RVX A;  2XU3 A;  2HD5 A;  4MZO A;  2PRE A;  2AVW A;  4CZW A;  1K3B B;  4RY2 A;  4FJC A;  1EWP A;  1CVZ A;  2F1G A;  2E03 A;  3N3K A;  2YJC A;  1PPP A;  4QBB A;  3S3R A;  2R9C A;  5CVM A;  2DC8 A;  3KWB X;  4YYR A;  2FTD A;  2G7Y A;  3LXS A;  3QSD A;  1ATK A;  1ME3 A;  3HD3 A;  4G54 A;  4N8W A;  2P7U A;  4W4U A;  5CHV A;  1NL6 A;  2G6D A;  4WA6 A;  3H8B A;  2AU1 A;  2VHF A;  3PDF A;  4DMY A;  2P86 A;  3F5V A;  1DEU A;  1HUC B;  4P6E A;  4OEM A;  1DF0 A;  2FQ9 A;  3B79 A;  4CDD B;  5JH3 A;  5CVO B;  2JQF R;  2C0Y A;  4N79 A;  3OVX A;  2XU5 A;  3P5U A;  4YV8 A;  3O1G A;  3BPM A;  2DCD A;  2NQI A;  3TNX A;  3OVZ A;  4MZS A;  1U9W A;  1ZCM A;  3F75 A;  1PPO A;  3P5W A;  4K7C A;  2HHN A;  4BQV A;  1F29 A;  1KHP A;  3C9E A;  5F02 A;  1KXR A;  3HHI A;  3QT4 A;  3CH3 X;  2PAD A;  2GHU A;  1AYV A;  2NQA A;  2YJ9 A;  2HH5 A;  3GCB A;  3MTN A;  1F2C A;  3OIS A;  2CIO A;  2FO5 A;  3MHH A;  2NQD B;  4I05 A;  2R6N A;  2R9M A;  1NB5 A;  2FUD A;  4AXL A;  4XUI A;  4PI3 A;  1M6D A;  4BS5 A;  2B1M A;  3S3Q A;  1EWM A;  2HXZ A;  4BSQ A;  4I04 A;  2FT2 A;  1AU0 A;  1NB3 A;  4CDE B;  1U5I A;  1PE6 A;  2G8J A;  1NPZ A;  3N3G A;  1XKG A;  3O0U A;  2PNS A;  1POP A;  1STF E;  3ERV A;  2Y6E A;  3I3T A;  1BGO A;  4Q8G A;  3BOW A;  1CJL A;  1SNK A;  1BY8 A;  1YK7 A;  1AU4 A;  1TLO A;  5EGW A;  2O6X A;  3IHP A;  2F7D A;  4YVA A;  1JQP A;  4P6G A;  2R9O A;  3AI8 A;  5FPW A;  1F2A A;  1Y08 A;  2B1N A;  1AU3 A;  3KW9 A;  1NQC A;  1TU6 A;  1Q6K A;  1PPN A;  4Q8H A;  2DCC A;  4CDC B;  5JA7 A;  1PPD A;  2FRQ A;  7PCK A;  3N4C A;  4ZUX U;  2ACT A;  3IUT A;  4PP1 A;  2AYN A;  2YJB A;  2PBH A;  3RVW A;  1U9Q X;  3OF9 A;  4PP2 E;  1PIP A;  2G8E A;  3K8U A;  3USV A;  1AIM A;  3D6S A;  4YYU A;  2AIM A;  2R9N A;  3H6S A;  1QXP A;  3CH2 X;  4YYS A;  4HWY A;  1KHQ A;  3V6C A;  9PAP A;  1BQI A;  4KLB A;  1ITO A;  4YYV A;  1BP4 A;  3NHE A;  3K9M A;  2E01 A;  3CBK A;  3MHS A;  1O0E A;  1MDW A;  1THE A;  2DCB A;  2XU1 A;  4QH6 A;  2AYO A;  1CQD A;  2BDZ A;  1AU2 A;  5PAD A;  1EWO A;  3QJ3 A;  4YYW A;  1X9Y A;  2NQG A;  2FYE A;  2IBI A;  1SP4 B;  2P0R A;  3RVV A;  1EF7 A;  3H7D A;  2BDL A;  3MOR A;  2AS8 A;  4W5C A;  2AUZ A;  5J94 A;  1ICF A;  2IPP B;  2YJ8 A;  3H89 A;  1MHW A;  8PCH A;  1ZIV A;  2DC7 A;  1YK8 A;  3U8E A;  2DZZ A;  3BPF A;  3PW3 A;  1CSB B;  3KX1 A;  1CV8 A;  1QOL A;  2JQG R;  6PAD A;  1EWL A;  2WBF X;  1GLO A;  3M99 A;  1ME4 A;  3IEJ A;  1MIR A;  2E00 A;  3LFY A;  2AUX A;  1IWD A;  4FK5 A;  3HHA A;  1VSN A;  3E1Z B;  1CTE A;  1F2B A;  3K24 A;  4CDF B;  3H8C A;  4X6H A;  3V6E A;  1CB5 A;  2YJ2 A;  3I06 A;  4XR7 A;  4PAD A;  1MS6 A; 
#chains in the Genus database with same CATH topology
 3IV2 A;  3IFU A;  2J7Q C;  2AGA A;  4DMX A;  2GFO A;  1PBH A;  3BCN A;  2ATO A;  1GMY A;  1PAD A;  4AXM A;  1YAL A;  2DZY A;  3WXF A;  3PNR A;  5CHT A;  1CPJ A;  1Y4H A;  4YYQ A;  2Y5B A;  3IMA A;  4QRX A;  4I07 A;  1KFU L;  2OUL A;  1QDQ A;  1YVB A;  4X6J A;  1PXV A;  3HWN A;  1GCB A;  1CS8 A;  2BU3 A;  4N4Z A;  1PCI A;  2VHS A;  2DJF B;  2OZ2 A;  4BPV A;  1GEC E;  1S4V A;  2ARY A;  1YZB A;  3KSE A;  5EF4 A;  3OF8 A;  1TL9 A;  3DF0 A;  3KKU A;  3P5V A;  3WXE A;  3BWK A;  4BS6 A;  1FH0 A;  1QMY A;  5A24 A;  3PBH A;  5K16 A;  4FIP A;  4X6I A;  3KWZ A;  1A6R A;  3WXG A;  2E02 A;  1U9V A;  1UKF A;  1MEM A;  1AEC A;  2DCA A;  2DJG B;  2CB5 A;  1AYU A;  3C0R A;  4QRG A;  1AYW A;  3ZUA A;  2XU4 A;  2DC9 A;  2OP3 A;  3KFQ A;  3CBJ A;  4BOS A;  1KFX L;  3IOQ A;  2DC6 A;  5CVN B;  2R9F A;  4QRV A;  4MSX A;  4A5U A;  1YT7 A;  1MEG A;  1NLJ A;  2H7J A;  3P5X A;  5JZE A;  1VJV A;  4W5B A;  1U9X A;  2FRA A;  3PRM A;  4OEL A;  3PT2 A;  4XZX A;  3BC3 A;  3RVX A;  4BOQ A;  2XU3 A;  2HD5 A;  4MZO A;  3B21 A;  2PRE A;  2AVW A;  1DKI A;  4ZTB A;  4CZW A;  1K3B B;  3TMP A;  4RY2 A;  4FJC A;  1EWP A;  2FE8 A;  1CVZ A;  2F1G A;  4BOP A;  2E03 A;  3N3K A;  2YJC A;  4RNA A;  1PPP A;  4QBB A;  4M0W A;  3S3R A;  2R9C A;  4BOU A;  5CVM A;  2DC8 A;  3BY4 A;  3KWB X;  4YYR A;  2FTD A;  2G7Y A;  3LXS A;  3QSD A;  1ATK A;  1ME3 A;  3HD3 A;  4G54 A;  4N8W A;  2P7U A;  4W4U A;  5CHV A;  1NL6 A;  2G6D A;  4WA6 A;  3TRK A;  3H8B A;  2AU1 A;  5KO3 A;  2VHF A;  4OVZ B;  3PDF A;  4GUA A;  4DMY A;  3W31 A;  2P86 A;  3F5V A;  1DEU A;  1HUC B;  4P6E A;  4OEM A;  4REZ A;  1DF0 A;  2FQ9 A;  3B79 A;  4CDD B;  2JTC A;  5JH3 A;  4RF1 A;  5CVO B;  2JQF R;  2C0Y A;  4N79 A;  3OVX A;  2JRI A;  2XU5 A;  3P5U A;  4YV8 A;  3O1G A;  3PRP A;  3BPM A;  2DCD A;  2NQI A;  3TNX A;  3OVZ A;  4MZS A;  1U9W A;  1ZCM A;  3F75 A;  1PPO A;  4BOZ A;  3P5W A;  4K7C A;  2HHN A;  4BQV A;  1F29 A;  1KHP A;  3C9E A;  5F02 A;  1KXR A;  3HHI A;  3QT4 A;  5EZS A;  3CH3 X;  2PAD A;  2GHU A;  1AYV A;  2NQA A;  2YJ9 A;  2HH5 A;  3GCB A;  3MTN A;  1F2C A;  3OIS A;  2CIO A;  2FO5 A;  3MHH A;  2NQD B;  4I05 A;  2R6N A;  2R9M A;  1NB5 A;  2FUD A;  4AXL A;  3MJ5 A;  4XUI A;  4PI3 A;  1M6D A;  4HXD B;  4BS5 A;  4RF0 A;  2B1M A;  3S3Q A;  5E6J A;  1EWM A;  2HXZ A;  4BSQ A;  4I04 A;  2FT2 A;  1AU0 A;  1NB3 A;  4CDE B;  1U5I A;  1PE6 A;  2G8J A;  1NPZ A;  3N3G A;  1XKG A;  3PSE A;  3O0U A;  2PNS A;  1POP A;  1STF E;  3ERV A;  4IUM A;  2Y6E A;  3I3T A;  1BGO A;  4Q8G A;  3BOW A;  1CJL A;  3ZNH A;  3PHU A;  1SNK A;  1BY8 A;  1YK7 A;  3MP2 A;  2UZJ A;  3PHW A;  1AU4 A;  1TLO A;  5EGW A;  2O6X A;  3IHP A;  4PT5 A;  4MI7 A;  2F7D A;  4YVA A;  1JQP A;  4P6G A;  2R9O A;  3AI8 A;  5FPW A;  1F2A A;  1Y08 A;  4D8I A;  2B1N A;  1AU3 A;  4D8E A;  3KW9 A;  1NQC A;  1TU6 A;  4MM3 B;  1Q6K A;  1PPN A;  3O65 A;  4Q8H A;  2DCC A;  2BTW A;  4CDC B;  5JA7 A;  1PPD A;  2FRQ A;  7PCK A;  3N4C A;  4ZUX U;  2ACT A;  3IUT A;  4RKX A;  4PP1 A;  2AYN A;  2YJB A;  2PBH A;  3RVW A;  1U9Q X;  3OF9 A;  4PP2 E;  1PVJ A;  1PIP A;  4OW0 A;  2G8E A;  3K8U A;  3USV A;  1AIM A;  4IP3 A;  2DOS A;  3D6S A;  4P16 A;  4YYU A;  2AIM A;  2R9N A;  3H6S A;  1QXP A;  3CH2 X;  4YYS A;  4HWY A;  1KHQ A;  3V6C A;  9PAP A;  3RNV A;  1BQI A;  2J7Q A;  4KLB A;  1ITO A;  4YYV A;  1BP4 A;  3NHE A;  3K9M A;  2E01 A;  3CBK A;  3MHS A;  1O0E A;  1MDW A;  1THE A;  2DCB A;  2XU1 A;  4QH6 A;  2AYO A;  1CQD A;  2BDZ A;  1AU2 A;  4WUR A;  5PAD A;  1EWO A;  3QJ3 A;  4YYW A;  1X9Y A;  2BTW B;  2NQG A;  2FYE A;  2IBI A;  1SP4 B;  3BB7 A;  2P0R A;  3RVV A;  1EF7 A;  3BBA A;  3H7D A;  2BDL A;  3MOR A;  2AS8 A;  4W5C A;  2AUZ A;  5J94 A;  5EZQ A;  1ICF A;  2Z84 A;  2IPP B;  2YJ8 A;  3H89 A;  4D8B A;  3E9S A;  1MHW A;  3OQC A;  8PCH A;  1ZIV A;  2DC7 A;  1YK8 A;  3U8E A;  2DZZ A;  3BPF A;  3PW3 A;  4OVZ A;  1CSB B;  3KX1 A;  1CV8 A;  1QOL A;  2JQG R;  6PAD A;  1EWL A;  3MTV A;  2WBF X;  1GLO A;  3M99 A;  1ME4 A;  3IEJ A;  1MIR A;  3PHX A;  2E00 A;  3LFY A;  2AUX A;  1IWD A;  4FK5 A;  3HHA A;  1VSN A;  2HWK A;  3E1Z B;  1CTE A;  1F2B A;  3K24 A;  4CDF B;  3W30 A;  3H8C A;  4X6H A;  3V6E A;  1CB5 A;  2YJ2 A;  4R3D A;  3I06 A;  4XR7 A;  4PAD A;  1MS6 A; 
#chains in the Genus database with same CATH homology
 3IV2 A;  4DMX A;  2GFO A;  1PBH A;  3BCN A;  2ATO A;  1GMY A;  1PAD A;  4AXM A;  1YAL A;  2DZY A;  3WXF A;  3PNR A;  5CHT A;  1CPJ A;  1Y4H A;  4YYQ A;  2Y5B A;  3IMA A;  4QRX A;  4I07 A;  1KFU L;  2OUL A;  1QDQ A;  1YVB A;  4X6J A;  1PXV A;  4GUZ A;  3HWN A;  4NV7 A;  1GCB A;  1CS8 A;  4N4Z A;  1PCI A;  2VHS A;  2DJF B;  2OZ2 A;  4BPV A;  1GEC E;  1S4V A;  2ARY A;  3KSE A;  5EF4 A;  3OF8 A;  1TL9 A;  3DF0 A;  3KKU A;  3P5V A;  3WXE A;  3BWK A;  4BS6 A;  1FH0 A;  1QMY A;  5A24 A;  3PBH A;  5K16 A;  4FIP A;  4X6I A;  3KWZ A;  1A6R A;  3WXG A;  2E02 A;  1U9V A;  3LTW A;  1W5R A;  1MEM A;  1AEC A;  2DCA A;  2DJG B;  2CB5 A;  1AYU A;  1GX3 A;  4QRG A;  1AYW A;  3ZUA A;  2XU4 A;  2DC9 A;  2OP3 A;  3KFQ A;  3CBJ A;  1KFX L;  3IOQ A;  2DC6 A;  5CVN B;  2R9F A;  2VFC A;  4QRV A;  4MSX A;  1E2T A;  1YT7 A;  1MEG A;  1NLJ A;  2H7J A;  3P5X A;  1VJV A;  4W5B A;  1U9X A;  2FRA A;  4OEL A;  3BC3 A;  3RVX A;  2XU3 A;  2HD5 A;  4MZO A;  2PRE A;  2AVW A;  4CZW A;  1K3B B;  4RY2 A;  4FJC A;  1W6F A;  1EWP A;  4C5P A;  1CVZ A;  2F1G A;  2E03 A;  3N3K A;  2YJC A;  1PPP A;  4QBB A;  3S3R A;  2R9C A;  5CVM A;  2DC8 A;  3KWB X;  4YYR A;  2FTD A;  2G7Y A;  3LXS A;  3QSD A;  1ATK A;  1ME3 A;  3HD3 A;  4G54 A;  4N8W A;  2P7U A;  4W4U A;  5CHV A;  1NL6 A;  2G6D A;  4WA6 A;  3H8B A;  2AU1 A;  2VHF A;  3PDF A;  4DMY A;  2P86 A;  3F5V A;  1DEU A;  1HUC B;  4P6E A;  4OEM A;  1DF0 A;  2FQ9 A;  3B79 A;  4NV8 A;  4CDD B;  5JH3 A;  5CVO B;  2JQF R;  2C0Y A;  4N79 A;  3OVX A;  2VFB A;  2XU5 A;  3P5U A;  4YV8 A;  3O1G A;  3BPM A;  3D9W A;  2DCD A;  2NQI A;  3TNX A;  3OVZ A;  4MZS A;  1U9W A;  1ZCM A;  3F75 A;  1PPO A;  3P5W A;  4K7C A;  2HHN A;  4BQV A;  1F29 A;  1KHP A;  3C9E A;  5F02 A;  1KXR A;  3HHI A;  3QT4 A;  3CH3 X;  2PAD A;  2GHU A;  1AYV A;  2NQA A;  2YJ9 A;  2HH5 A;  3GCB A;  3MTN A;  1F2C A;  3OIS A;  2CIO A;  2FO5 A;  3MHH A;  2NQD B;  4I05 A;  2R6N A;  2R9M A;  1NB5 A;  2FUD A;  4AXL A;  4XUI A;  4PI3 A;  1M6D A;  4BS5 A;  2B1M A;  3S3Q A;  1EWM A;  2HXZ A;  4BSQ A;  4I04 A;  2FT2 A;  1AU0 A;  1NB3 A;  4CDE B;  1U5I A;  1PE6 A;  2G8J A;  1NPZ A;  3N3G A;  1XKG A;  3O0U A;  2PNS A;  1POP A;  1STF E;  3ERV A;  2Y6E A;  1W4T A;  3I3T A;  1BGO A;  4Q8G A;  3BOW A;  1CJL A;  1SNK A;  1BY8 A;  1YK7 A;  4B55 A;  1AU4 A;  1TLO A;  5EGW A;  2O6X A;  3IHP A;  2F7D A;  4YVA A;  1JQP A;  4P6G A;  2R9O A;  3AI8 A;  5FPW A;  1F2A A;  1Y08 A;  2B1N A;  1AU3 A;  3KW9 A;  1NQC A;  1TU6 A;  1Q6K A;  1PPN A;  4Q8H A;  2DCC A;  4CDC B;  5JA7 A;  1PPD A;  2FRQ A;  7PCK A;  3N4C A;  4ZUX U;  2ACT A;  3IUT A;  4PP1 A;  2AYN A;  2YJB A;  2PBH A;  3RVW A;  1U9Q X;  3OF9 A;  4PP2 E;  1PIP A;  2G8E A;  3K8U A;  3USV A;  1AIM A;  3D6S A;  4YYU A;  2AIM A;  2R9N A;  3H6S A;  1QXP A;  3CH2 X;  4YYS A;  4HWY A;  1KHQ A;  3V6C A;  9PAP A;  1BQI A;  4KLB A;  1ITO A;  4YYV A;  1BP4 A;  3NHE A;  3K9M A;  2E01 A;  3CBK A;  3MHS A;  1O0E A;  1MDW A;  1THE A;  2DCB A;  2XU1 A;  4QH6 A;  2AYO A;  1CQD A;  2BDZ A;  1AU2 A;  5PAD A;  1EWO A;  3QJ3 A;  4YYW A;  1X9Y A;  2NQG A;  2FYE A;  4BGF A;  2IBI A;  1SP4 B;  2P0R A;  3RVV A;  1EF7 A;  3H7D A;  2BDL A;  3MOR A;  2AS8 A;  4W5C A;  2AUZ A;  5J94 A;  1ICF A;  2IPP B;  2YJ8 A;  3H89 A;  1MHW A;  8PCH A;  1ZIV A;  2DC7 A;  1YK8 A;  3U8E A;  2DZZ A;  3BPF A;  3PW3 A;  1CSB B;  3KX1 A;  1CV8 A;  1QOL A;  2JQG R;  6PAD A;  1EWL A;  2WBF X;  1GLO A;  3M99 A;  1ME4 A;  3IEJ A;  1MIR A;  2BSZ A;  2E00 A;  3LFY A;  2AUX A;  1IWD A;  4FK5 A;  3HHA A;  1VSN A;  3E1Z B;  1CTE A;  1F2B A;  3K24 A;  4CDF B;  3H8C A;  4X6H A;  3V6E A;  1CB5 A;  2YJ2 A;  3I06 A;  4XR7 A;  4PAD A;  1MS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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