1NL6A

Crystal structure of the cysteine protease human cathepsin k in complex with a covalent azepanone inhibitor
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Azepanone-based inhibitors of human and rat cathepsin K
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 54
structure length 215
sequence length 215
chains with identical sequence B
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2003-01-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1nl6A00
2DJFB 2R6NA 3ZUAA 4HWYA 2DCAA 4YYUA 2DCCA 5JA7A 1U5IA 2HHNA 1TLOA 4RY2A 2BDZA 1CB5A 2ATOA 2XU1A 2DC8A 1XKGA 3CH2X 5F02A 3OISA 2Y6EA 2DCDA 1SNKA 1U9VA 3V6EA 2H7JA 3E1ZB 3IMAA 1AU3A 1PPOA 4BSQA 1PE6A 3LXSA 1ITOA 3BOWA 1KHPA 1Y08A 3C9EA 4W5BA 2O6XA 3D6SA 4Q8HA 2FO5A 2F7DA 3MTNA 1QDQA 2P86A 1AIMA 2OZ2A 1KFUL 1KXRA 4BS5A 4MZOA 4PADA 2AYOA 4YV8A 1ZCMA 3S3QA 2FUDA 2P0RA 1STFE 3K24A 1SP4B 1ME4A 1PCIA 5A24A 3MHHA 2WBFX 2OP3A 5CVMA 1GMYA 1NB5A 1QOLA 1VSNA 4YYWA 2ACTA 3MHSA 4MZSA 1AU2A 1F2AA 2AYNA 4QH6A 3MORA 4P6EA 2DC9A 4PI3A 1AU4A 3AI8A 2XU4A 1BGOA 3KSEA 1NQCA 3KFQA 2HD5A 4KLBA 4W5CA 1HUCB 2AUXA 4MSXA 2P7UA 2Y5BA 1QXPA 2B1MA 3H8CA 2R9FA 7PCKA 4QRGA 2FTDA 1NPZA 1MHWA 3K8UA 4DMYA 3PNRA 4BPVA 2JQFR 3RVXA 4K7CA 5JH3A 3CBKA 1ZIVA 2F1GA 1PXVA 1YK7A 5EGWA 3HD3A 1QMYA 1EWLA 2R9OA 2PNSA 2XU5A 4N4ZA 3B79A 3N3GA 1KHQA 4BS6A 2C0YA 3KWBX 3WXEA 3O1GA 2E00A 1Y4HA 1FH0A 4CZWA 4W4UA 2R9CA 4BQVA 1YALA 2FRAA 1F2CA 2XU3A 2YJ2A 1GECE 3U8EA 1BP4A 3M99A 1U9QX 1NB3A 3CH3X 3QT4A 1CJLA 1CV8A 1KFXL 3BCNA 3N4CA 2DCBA 2YJ9A 3USVA 1U9XA 2DC7A 4DMXA 2YJCA 3V6CA 4X6IA 1X9YA 4QBBA 4G54A 2YJBA 1YK8A 1O0EA 4N79A 4CDCB 1MEMA 3H7DA 1S4VA 2FYEA 1JQPA 4OEMA 1AU0A 3LFYA 4N8WA 1ME3A 4AXMA 4FK5A 4Q8GA 1PPNA 1GCBA 1YVBA 2E01A 1AYWA 1F2BA 1VJVA 3HHAA 2FT2A 3H6SA 3IEJA 1F29A 1ICFA 1PIPA 1PPPA 2DZZA 4YYRA 4I07A 2NQGA 4CDEB 5K16A 3P5XA 3IHPA 1AYVA 3OF8A 3P5UA 3F5VA 1PBHA 4XUIA 1CPJA 1MS6A 3CBJA 1IWDA 2NQIA 3DF0A 2AUZA 1EWMA 3O0UA 2GHUA 4WA6A 2BDLA 1Q6KA 1ATKA 2G7YA 4I05A 1AYUA 4YVAA 4FJCA 3OVXA 1EWPA 1CQDA 2VHSA 3PW3A 3H89A 4XR7A 6PADA 3S3RA 5PADA 4X6HA 3HWNA 5CVNB 5J94A 3WXGA 2E03A 4YYSA 3BPFA 2IPPB 2FQ9A 3K9MA 4YYVA 2AIMA 3IOQA 3HHIA 4P6GA 1A6RA 4FIPA 1CS8A 2ARYA 3WXFA 3ERVA 3KWZA 3IV2A 1DEUA 2PREA 3BPMA 2AVWA 2VHFA 2JQGR 3P5VA 4AXLA 1CTEA 4CDDB 2NQAA 8PCHA 3IUTA 4PP1A 1THEA 1CVZA 3RVWA 4ZUXU 2PBHA 1NLJA 1TU6A 3I06A 3OF9A 2CIOA 1CSBB 2FRQA 5FPWA 2PADA 1EF7A 1BQIA 4QRVA 3BC3A 3KX1A 3RVVA 1EWOA 3GCBA 3N3KA 1MEGA 2HXZA 1U9WA 1NL6A 1TL9A 1YT7A 3I3TA 4CDFB 2AU1A 3QSDA 1AECA 9PAPA 2DC6A 1BY8A 4YYQA 1GLOA 2R9MA 3BWKA 3H8BA 3KKUA 3F75A 2IBIA 1PADA 2E02A 2G6DA 5CVOB 1PPDA 3P5WA 1M6DA 3KW9A 2B1NA 1DF0A 2AS8A 4I04A 2DZYA 3NHEA 2DJGB 4QRXA 2GFOA 1K3BB 2G8EA 4PP2E 3TNXA 3OVZA 1MIRA 5CHTA 2R9NA 4X6JA 2OULA 2NQDB 3PBHA 2CB5A 3PDFA 3QJ3A 4OELA 5CHVA 2HH5A 5EF4A 1POPA 2YJ8A 2G8JA 1MDWA
chains in the Genus database with same CATH superfamily
2DJFB 2R6NA 3ZUAA 4HWYA 2DCAA 5JZEA 4XZXA 4YYUA 5EZQA 2DCCA 4A5UA 5JA7A 1U5IA 2HHNA 1TLOA 4RY2A 2BDZA 1CB5A 4D8EA 2ATOA 2XU1A 2DC8A 1XKGA 3CH2X 5F02A 2J7QA 3OISA 2Y6EA 2DCDA 1SNKA 2DOSA 1U9VA 2JTCA 3V6EA 2H7JA 3E1ZB 3IMAA 1AU3A 1PPOA 4HXDB 4D8BA 4BSQA 2JRIA 1PE6A 3LXSA 1ITOA 3BOWA 1KHPA 1Y08A 3C9EA 3TRKA 4W5BA 3PRPA 2O6XA 3D6SA 3MJ5A 4Q8HA 2FO5A 2F7DA 3MTNA 4MM3B 1QDQA 3MP2A 4BOQA 2P86A 3PRMA 1AIMA 2OZ2A 1KFUL 2BU3A 3C0RA 1KXRA 4BS5A 4MZOA 4PADA 2AYOA 4YV8A 1ZCMA 5E6JA 3S3QA 2FUDA 2P0RA 1STFE 3K24A 1SP4B 1ME4A 3PSEA 1PCIA 5A24A 3MHHA 2WBFX 2OP3A 4ZTBA 5CVMA 1GMYA 1NB5A 1QOLA 3B21A 5EZSA 1VSNA 4YYWA 1YZBA 2ACTA 3BY4A 3MHSA 4MZSA 1AU2A 1F2AA 2AYNA 4QH6A 3MORA 4P6EA 2DC9A 4PI3A 1AU4A 3AI8A 2XU4A 1BGOA 3KSEA 1NQCA 4WURA 3KFQA 2HD5A 4KLBA 4W5CA 1HUCB 2AUXA 4MSXA 2HWKA 2P7UA 2Y5BA 1QXPA 2B1MA 1UKFA 3H8CA 2R9FA 7PCKA 4QRGA 2FTDA 1NPZA 1MHWA 3K8UA 4DMYA 3PNRA 4BPVA 2JQFR 3RVXA 4K7CA 5JH3A 3CBKA 1ZIVA 2F1GA 3PHUA 1PXVA 1YK7A 5EGWA 3HD3A 1QMYA 4IUMA 1EWLA 4REZA 4M0WA 2R9OA 2PNSA 2XU5A 4N4ZA 3B79A 3PT2A 2BTWB 3N3GA 1KHQA 4BS6A 2C0YA 3KWBX 3WXEA 3O1GA 2E00A 1Y4HA 1FH0A 4CZWA 4W4UA 2R9CA 4BQVA 1YALA 3W31A 2FRAA 1F2CA 2XU3A 2FE8A 4RNAA 2YJ2A 1GECE 4RF0A 3U8EA 1BP4A 3M99A 1U9QX 1NB3A 3CH3X 3QT4A 1CJLA 1CV8A 1KFXL 3BCNA 3N4CA 2DCBA 2YJ9A 3USVA 1U9XA 2DC7A 4DMXA 2YJCA 3V6CA 4X6IA 1X9YA 4QBBA 3MTVA 4G54A 2Z84A 2YJBA 1YK8A 4OVZB 1O0EA 4N79A 4CDCB 1MEMA 3H7DA 1S4VA 2FYEA 1JQPA 4OEMA 1AU0A 3LFYA 4N8WA 1ME3A 4AXMA 4FK5A 4Q8GA 1PPNA 1MDWA 1GCBA 1YVBA 2E01A 1AYWA 1F2BA 1DKIA 1VJVA 3HHAA 2FT2A 3H6SA 3IEJA 1F29A 4OW0A 4RKXA 1ICFA 1PIPA 1PPPA 3PHXA 2DZZA 4YYRA 4I07A 2NQGA 4CDEB 4BOPA 5K16A 3P5XA 2J7QC 4MI7A 3IHPA 1AYVA 3OF8A 3RNVA 3P5UA 3F5VA 1PBHA 4XUIA 1CPJA 1MS6A 3CBJA 1IWDA 2NQIA 3DF0A 2AUZA 1EWMA 3O0UA 2GHUA 4WA6A 2BDLA 1Q6KA 1ATKA 2G7YA 4I05A 4PT5A 1AYUA 4YVAA 4R3DA 4FJCA 5KO3A 3OVXA 1EWPA 1CQDA 2VHSA 3PW3A 3H89A 4XR7A 6PADA 3O65A 3S3RA 5PADA 3ZNHA 4X6HA 3HWNA 5CVNB 5J94A 3WXGA 3W30A 2E03A 4YYSA 3BPFA 2IPPB 2FQ9A 3K9MA 3PHWA 4YYVA 2AIMA 4BOSA 3IOQA 3HHIA 4GUAA 4P6GA 1A6RA 4FIPA 1CS8A 2ARYA 3WXFA 4D8IA 3ERVA 3KWZA 3IV2A 1DEUA 2PREA 3BPMA 2AVWA 2VHFA 2JQGR 3P5VA 2BTWA 4AXLA 1CTEA 4CDDB 2NQAA 8PCHA 3IUTA 4PP1A 1THEA 3TMPA 1CVZA 3RVWA 4BOUA 4ZUXU 2PBHA 1NLJA 1TU6A 3I06A 3OF9A 2CIOA 1CSBB 2FRQA 5FPWA 4RF1A 2PADA 1EF7A 1BQIA 4QRVA 3BC3A 3KX1A 4IP3A 3RVVA 1EWOA 3GCBA 3N3KA 1MEGA 2HXZA 1PVJA 1U9WA 1NL6A 3BB7A 1TL9A 1YT7A 3I3TA 4CDFB 2AU1A 3QSDA 1AECA 9PAPA 2DC6A 1BY8A 4YYQA 1GLOA 2R9MA 3BWKA 3H8BA 3KKUA 4OVZA 3F75A 4BOZA 2IBIA 1PADA 2E02A 3E9SA 2G6DA 5CVOB 1PPDA 3P5WA 1M6DA 3KW9A 2B1NA 1DF0A 2AS8A 3OQCA 2AGAA 4I04A 2DZYA 3NHEA 2DJGB 4QRXA 2GFOA 1K3BB 2G8EA 4PP2E 3TNXA 3OVZA 4P16A 1MIRA 3IFUA 5CHTA 2R9NA 4X6JA 2OULA 2NQDB 3PBHA 2CB5A 3PDFA 3QJ3A 4OELA 5CHVA 2HH5A 5EF4A 1POPA 2YJ8A 2G8JA 2UZJA 3BBAA
chains in the Genus database with same CATH topology
2DJFB 2R6NA 3ZUAA 4HWYA 2DCAA 4YYUA 2DCCA 5JA7A 1U5IA 2HHNA 1TLOA 4RY2A 2BDZA 1CB5A 4GUZA 2ATOA 1W4TA 2XU1A 2DC8A 1XKGA 3CH2X 5F02A 3OISA 2Y6EA 2DCDA 1SNKA 1U9VA 3V6EA 2H7JA 3E1ZB 3IMAA 1AU3A 1PPOA 4BSQA 1PE6A 3LXSA 1ITOA 3BOWA 1KHPA 1Y08A 3C9EA 4W5BA 2O6XA 3D6SA 4Q8HA 2FO5A 2F7DA 3MTNA 1QDQA 2P86A 1AIMA 2OZ2A 1KFUL 1KXRA 4BS5A 4MZOA 4PADA 2AYOA 4YV8A 1ZCMA 3S3QA 2FUDA 2P0RA 1STFE 3K24A 1SP4B 1ME4A 1PCIA 5A24A 3MHHA 2WBFX 2OP3A 5CVMA 1GMYA 1W5RA 1NB5A 1QOLA 1VSNA 4YYWA 2ACTA 3MHSA 4MZSA 1AU2A 1F2AA 2AYNA 4QH6A 3MORA 4P6EA 2DC9A 4PI3A 1AU4A 3AI8A 2XU4A 1BGOA 3KSEA 1NQCA 3KFQA 1GX3A 2HD5A 4KLBA 4W5CA 1HUCB 2AUXA 4MSXA 2P7UA 2Y5BA 1QXPA 2B1MA 3H8CA 2R9FA 7PCKA 4QRGA 2FTDA 1NPZA 1MHWA 1E2TA 3K8UA 4DMYA 3PNRA 4BPVA 2JQFR 3RVXA 4K7CA 5JH3A 3CBKA 1ZIVA 2F1GA 1PXVA 1YK7A 5EGWA 3HD3A 1QMYA 1EWLA 2R9OA 2PNSA 2XU5A 4N4ZA 4B55A 3B79A 3N3GA 1KHQA 4BS6A 2C0YA 3KWBX 3WXEA 3O1GA 2E00A 1Y4HA 1FH0A 4CZWA 4W4UA 2R9CA 4BQVA 1YALA 2FRAA 1F2CA 2XU3A 2YJ2A 1GECE 3U8EA 1BP4A 3M99A 1U9QX 1NB3A 3CH3X 3D9WA 3QT4A 4NV8A 1CJLA 1CV8A 1KFXL 3BCNA 3N4CA 2DCBA 3LTWA 2YJ9A 3USVA 1U9XA 2DC7A 4DMXA 2YJCA 3V6CA 4X6IA 1X9YA 4QBBA 4G54A 2YJBA 1YK8A 1O0EA 4N79A 4CDCB 1MEMA 3H7DA 1S4VA 2FYEA 1JQPA 4OEMA 1AU0A 3LFYA 4N8WA 1ME3A 4AXMA 4FK5A 4Q8GA 1PPNA 1GCBA 1YVBA 2E01A 1AYWA 1F2BA 1VJVA 3HHAA 2FT2A 4NV7A 3H6SA 3IEJA 1F29A 1ICFA 1PIPA 1PPPA 2DZZA 4YYRA 4I07A 2NQGA 4CDEB 5K16A 3P5XA 3IHPA 1W6FA 1AYVA 3OF8A 3P5UA 3F5VA 1PBHA 4XUIA 1CPJA 1MS6A 3CBJA 1IWDA 2NQIA 3DF0A 2AUZA 1EWMA 2BSZA 3O0UA 2GHUA 4WA6A 2BDLA 1Q6KA 1ATKA 2G7YA 2VFBA 4I05A 1AYUA 4YVAA 4FJCA 3OVXA 1EWPA 1CQDA 2VHSA 3PW3A 3H89A 4XR7A 6PADA 3S3RA 5PADA 4X6HA 3HWNA 5CVNB 5J94A 3WXGA 2E03A 4YYSA 3BPFA 2IPPB 2FQ9A 3K9MA 4YYVA 2AIMA 3IOQA 3HHIA 4P6GA 1A6RA 4FIPA 1CS8A 2ARYA 3WXFA 3ERVA 3KWZA 3IV2A 1DEUA 2PREA 3BPMA 2AVWA 2VHFA 2JQGR 3P5VA 4AXLA 1CTEA 4CDDB 2NQAA 8PCHA 3IUTA 4PP1A 1THEA 2VFCA 1CVZA 3RVWA 4ZUXU 2PBHA 1NLJA 1TU6A 3I06A 3OF9A 2CIOA 1CSBB 2FRQA 5FPWA 2PADA 1EF7A 1BQIA 4QRVA 3BC3A 3KX1A 3RVVA 1EWOA 3GCBA 3N3KA 4C5PA 1MEGA 2HXZA 1U9WA 1NL6A 1TL9A 1YT7A 3I3TA 4CDFB 2AU1A 3QSDA 1AECA 9PAPA 2DC6A 1BY8A 4YYQA 1GLOA 2R9MA 3BWKA 3H8BA 3KKUA 3F75A 2IBIA 1PADA 2E02A 2G6DA 5CVOB 1PPDA 3P5WA 1M6DA 3KW9A 2B1NA 1DF0A 2AS8A 4I04A 2DZYA 3NHEA 2DJGB 4QRXA 2GFOA 1K3BB 2G8EA 4PP2E 3TNXA 3OVZA 4BGFA 1MIRA 5CHTA 2R9NA 4X6JA 2OULA 2NQDB 3PBHA 2CB5A 3PDFA 3QJ3A 4OELA 5CHVA 2HH5A 5EF4A 1POPA 2YJ8A 2G8JA 1MDWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DJF B;  2R6N A;  3ZUA A;  4HWY A;  2DCA A;  4YYU A;  2DCC A;  5JA7 A;  1U5I A;  2HHN A;  1TLO A;  4RY2 A;  2BDZ A;  1CB5 A;  2ATO A;  2XU1 A;  2DC8 A;  1XKG A;  3CH2 X;  5F02 A;  3OIS A;  2Y6E A;  2DCD A;  1SNK A;  1U9V A;  3V6E A;  2H7J A;  3E1Z B;  3IMA A;  1AU3 A;  1PPO A;  4BSQ A;  1PE6 A;  3LXS A;  1ITO A;  3BOW A;  1KHP A;  1Y08 A;  3C9E A;  4W5B A;  2O6X A;  3D6S A;  4Q8H A;  2FO5 A;  2F7D A;  3MTN A;  1QDQ A;  2P86 A;  1AIM A;  2OZ2 A;  1KFU L;  1KXR A;  4BS5 A;  4MZO A;  4PAD A;  2AYO A;  4YV8 A;  1ZCM A;  3S3Q A;  2FUD A;  2P0R A;  1STF E;  3K24 A;  1SP4 B;  1ME4 A;  1PCI A;  5A24 A;  3MHH A;  2WBF X;  2OP3 A;  5CVM A;  1GMY A;  1NB5 A;  1QOL A;  1VSN A;  4YYW A;  2ACT A;  3MHS A;  4MZS A;  1AU2 A;  1F2A A;  2AYN A;  4QH6 A;  3MOR A;  4P6E A;  2DC9 A;  4PI3 A;  1AU4 A;  3AI8 A;  2XU4 A;  1BGO A;  3KSE A;  1NQC A;  3KFQ A;  2HD5 A;  4KLB A;  4W5C A;  1HUC B;  2AUX A;  4MSX A;  2P7U A;  2Y5B A;  1QXP A;  2B1M A;  3H8C A;  2R9F A;  7PCK A;  4QRG A;  2FTD A;  1NPZ A;  1MHW A;  3K8U A;  4DMY A;  3PNR A;  4BPV A;  2JQF R;  3RVX A;  4K7C A;  5JH3 A;  3CBK A;  1ZIV A;  2F1G A;  1PXV A;  1YK7 A;  5EGW A;  3HD3 A;  1QMY A;  1EWL A;  2R9O A;  2PNS A;  2XU5 A;  4N4Z A;  3B79 A;  3N3G A;  1KHQ A;  4BS6 A;  2C0Y A;  3KWB X;  3WXE A;  3O1G A;  2E00 A;  1Y4H A;  1FH0 A;  4CZW A;  4W4U A;  2R9C A;  4BQV A;  1YAL A;  2FRA A;  1F2C A;  2XU3 A;  2YJ2 A;  1GEC E;  3U8E A;  1BP4 A;  3M99 A;  1U9Q X;  1NB3 A;  3CH3 X;  3QT4 A;  1CJL A;  1CV8 A;  1KFX L;  3BCN A;  3N4C A;  2DCB A;  2YJ9 A;  3USV A;  1U9X A;  2DC7 A;  4DMX A;  2YJC A;  3V6C A;  4X6I A;  1X9Y A;  4QBB A;  4G54 A;  2YJB A;  1YK8 A;  1O0E A;  4N79 A;  4CDC B;  1MEM A;  3H7D A;  1S4V A;  2FYE A;  1JQP A;  4OEM A;  1AU0 A;  3LFY A;  4N8W A;  1ME3 A;  4AXM A;  4FK5 A;  4Q8G A;  1PPN A;  1GCB A;  1YVB A;  2E01 A;  1AYW A;  1F2B A;  1VJV A;  3HHA A;  2FT2 A;  3H6S A;  3IEJ A;  1F29 A;  1ICF A;  1PIP A;  1PPP A;  2DZZ A;  4YYR A;  4I07 A;  2NQG A;  4CDE B;  5K16 A;  3P5X A;  3IHP A;  1AYV A;  3OF8 A;  3P5U A;  3F5V A;  1PBH A;  4XUI A;  1CPJ A;  1MS6 A;  3CBJ A;  1IWD A;  2NQI A;  3DF0 A;  2AUZ A;  1EWM A;  3O0U A;  2GHU A;  4WA6 A;  2BDL A;  1Q6K A;  1ATK A;  2G7Y A;  4I05 A;  1AYU A;  4YVA A;  4FJC A;  3OVX A;  1EWP A;  1CQD A;  2VHS A;  3PW3 A;  3H89 A;  4XR7 A;  6PAD A;  3S3R A;  5PAD A;  4X6H A;  3HWN A;  5CVN B;  5J94 A;  3WXG A;  2E03 A;  4YYS A;  3BPF A;  2IPP B;  2FQ9 A;  3K9M A;  4YYV A;  2AIM A;  3IOQ A;  3HHI A;  4P6G A;  1A6R A;  4FIP A;  1CS8 A;  2ARY A;  3WXF A;  3ERV A;  3KWZ A;  3IV2 A;  1DEU A;  2PRE A;  3BPM A;  2AVW A;  2VHF A;  2JQG R;  3P5V A;  4AXL A;  1CTE A;  4CDD B;  2NQA A;  8PCH A;  3IUT A;  4PP1 A;  1THE A;  1CVZ A;  3RVW A;  4ZUX U;  2PBH A;  1NLJ A;  1TU6 A;  3I06 A;  3OF9 A;  2CIO A;  1CSB B;  2FRQ A;  5FPW A;  2PAD A;  1EF7 A;  1BQI A;  4QRV A;  3BC3 A;  3KX1 A;  3RVV A;  1EWO A;  3GCB A;  3N3K A;  1MEG A;  2HXZ A;  1U9W A;  1NL6 A;  1TL9 A;  1YT7 A;  3I3T A;  4CDF B;  2AU1 A;  3QSD A;  1AEC A;  9PAP A;  2DC6 A;  1BY8 A;  4YYQ A;  1GLO A;  2R9M A;  3BWK A;  3H8B A;  3KKU A;  3F75 A;  2IBI A;  1PAD A;  2E02 A;  2G6D A;  5CVO B;  1PPD A;  3P5W A;  1M6D A;  3KW9 A;  2B1N A;  1DF0 A;  2AS8 A;  4I04 A;  2DZY A;  3NHE A;  2DJG B;  4QRX A;  2GFO A;  1K3B B;  2G8E A;  4PP2 E;  3TNX A;  3OVZ A;  1MIR A;  5CHT A;  2R9N A;  4X6J A;  2OUL A;  2NQD B;  3PBH A;  2CB5 A;  3PDF A;  3QJ3 A;  4OEL A;  5CHV A;  2HH5 A;  5EF4 A;  1POP A;  2YJ8 A;  2G8J A;  1MDW A; 
#chains in the Genus database with same CATH topology
 2DJF B;  2R6N A;  3ZUA A;  4HWY A;  2DCA A;  5JZE A;  4XZX A;  4YYU A;  5EZQ A;  2DCC A;  4A5U A;  5JA7 A;  1U5I A;  2HHN A;  1TLO A;  4RY2 A;  2BDZ A;  1CB5 A;  4D8E A;  2ATO A;  2XU1 A;  2DC8 A;  1XKG A;  3CH2 X;  5F02 A;  2J7Q A;  3OIS A;  2Y6E A;  2DCD A;  1SNK A;  2DOS A;  1U9V A;  2JTC A;  3V6E A;  2H7J A;  3E1Z B;  3IMA A;  1AU3 A;  1PPO A;  4HXD B;  4D8B A;  4BSQ A;  2JRI A;  1PE6 A;  3LXS A;  1ITO A;  3BOW A;  1KHP A;  1Y08 A;  3C9E A;  3TRK A;  4W5B A;  3PRP A;  2O6X A;  3D6S A;  3MJ5 A;  4Q8H A;  2FO5 A;  2F7D A;  3MTN A;  4MM3 B;  1QDQ A;  3MP2 A;  4BOQ A;  2P86 A;  3PRM A;  1AIM A;  2OZ2 A;  1KFU L;  2BU3 A;  3C0R A;  1KXR A;  4BS5 A;  4MZO A;  4PAD A;  2AYO A;  4YV8 A;  1ZCM A;  5E6J A;  3S3Q A;  2FUD A;  2P0R A;  1STF E;  3K24 A;  1SP4 B;  1ME4 A;  3PSE A;  1PCI A;  5A24 A;  3MHH A;  2WBF X;  2OP3 A;  4ZTB A;  5CVM A;  1GMY A;  1NB5 A;  1QOL A;  3B21 A;  5EZS A;  1VSN A;  4YYW A;  1YZB A;  2ACT A;  3BY4 A;  3MHS A;  4MZS A;  1AU2 A;  1F2A A;  2AYN A;  4QH6 A;  3MOR A;  4P6E A;  2DC9 A;  4PI3 A;  1AU4 A;  3AI8 A;  2XU4 A;  1BGO A;  3KSE A;  1NQC A;  4WUR A;  3KFQ A;  2HD5 A;  4KLB A;  4W5C A;  1HUC B;  2AUX A;  4MSX A;  2HWK A;  2P7U A;  2Y5B A;  1QXP A;  2B1M A;  1UKF A;  3H8C A;  2R9F A;  7PCK A;  4QRG A;  2FTD A;  1NPZ A;  1MHW A;  3K8U A;  4DMY A;  3PNR A;  4BPV A;  2JQF R;  3RVX A;  4K7C A;  5JH3 A;  3CBK A;  1ZIV A;  2F1G A;  3PHU A;  1PXV A;  1YK7 A;  5EGW A;  3HD3 A;  1QMY A;  4IUM A;  1EWL A;  4REZ A;  4M0W A;  2R9O A;  2PNS A;  2XU5 A;  4N4Z A;  3B79 A;  3PT2 A;  2BTW B;  3N3G A;  1KHQ A;  4BS6 A;  2C0Y A;  3KWB X;  3WXE A;  3O1G A;  2E00 A;  1Y4H A;  1FH0 A;  4CZW A;  4W4U A;  2R9C A;  4BQV A;  1YAL A;  3W31 A;  2FRA A;  1F2C A;  2XU3 A;  2FE8 A;  4RNA A;  2YJ2 A;  1GEC E;  4RF0 A;  3U8E A;  1BP4 A;  3M99 A;  1U9Q X;  1NB3 A;  3CH3 X;  3QT4 A;  1CJL A;  1CV8 A;  1KFX L;  3BCN A;  3N4C A;  2DCB A;  2YJ9 A;  3USV A;  1U9X A;  2DC7 A;  4DMX A;  2YJC A;  3V6C A;  4X6I A;  1X9Y A;  4QBB A;  3MTV A;  4G54 A;  2Z84 A;  2YJB A;  1YK8 A;  4OVZ B;  1O0E A;  4N79 A;  4CDC B;  1MEM A;  3H7D A;  1S4V A;  2FYE A;  1JQP A;  4OEM A;  1AU0 A;  3LFY A;  4N8W A;  1ME3 A;  4AXM A;  4FK5 A;  4Q8G A;  1PPN A;  1MDW A;  1GCB A;  1YVB A;  2E01 A;  1AYW A;  1F2B A;  1DKI A;  1VJV A;  3HHA A;  2FT2 A;  3H6S A;  3IEJ A;  1F29 A;  4OW0 A;  4RKX A;  1ICF A;  1PIP A;  1PPP A;  3PHX A;  2DZZ A;  4YYR A;  4I07 A;  2NQG A;  4CDE B;  4BOP A;  5K16 A;  3P5X A;  2J7Q C;  4MI7 A;  3IHP A;  1AYV A;  3OF8 A;  3RNV A;  3P5U A;  3F5V A;  1PBH A;  4XUI A;  1CPJ A;  1MS6 A;  3CBJ A;  1IWD A;  2NQI A;  3DF0 A;  2AUZ A;  1EWM A;  3O0U A;  2GHU A;  4WA6 A;  2BDL A;  1Q6K A;  1ATK A;  2G7Y A;  4I05 A;  4PT5 A;  1AYU A;  4YVA A;  4R3D A;  4FJC A;  5KO3 A;  3OVX A;  1EWP A;  1CQD A;  2VHS A;  3PW3 A;  3H89 A;  4XR7 A;  6PAD A;  3O65 A;  3S3R A;  5PAD A;  3ZNH A;  4X6H A;  3HWN A;  5CVN B;  5J94 A;  3WXG A;  3W30 A;  2E03 A;  4YYS A;  3BPF A;  2IPP B;  2FQ9 A;  3K9M A;  3PHW A;  4YYV A;  2AIM A;  4BOS A;  3IOQ A;  3HHI A;  4GUA A;  4P6G A;  1A6R A;  4FIP A;  1CS8 A;  2ARY A;  3WXF A;  4D8I A;  3ERV A;  3KWZ A;  3IV2 A;  1DEU A;  2PRE A;  3BPM A;  2AVW A;  2VHF A;  2JQG R;  3P5V A;  2BTW A;  4AXL A;  1CTE A;  4CDD B;  2NQA A;  8PCH A;  3IUT A;  4PP1 A;  1THE A;  3TMP A;  1CVZ A;  3RVW A;  4BOU A;  4ZUX U;  2PBH A;  1NLJ A;  1TU6 A;  3I06 A;  3OF9 A;  2CIO A;  1CSB B;  2FRQ A;  5FPW A;  4RF1 A;  2PAD A;  1EF7 A;  1BQI A;  4QRV A;  3BC3 A;  3KX1 A;  4IP3 A;  3RVV A;  1EWO A;  3GCB A;  3N3K A;  1MEG A;  2HXZ A;  1PVJ A;  1U9W A;  1NL6 A;  3BB7 A;  1TL9 A;  1YT7 A;  3I3T A;  4CDF B;  2AU1 A;  3QSD A;  1AEC A;  9PAP A;  2DC6 A;  1BY8 A;  4YYQ A;  1GLO A;  2R9M A;  3BWK A;  3H8B A;  3KKU A;  4OVZ A;  3F75 A;  4BOZ A;  2IBI A;  1PAD A;  2E02 A;  3E9S A;  2G6D A;  5CVO B;  1PPD A;  3P5W A;  1M6D A;  3KW9 A;  2B1N A;  1DF0 A;  2AS8 A;  3OQC A;  2AGA A;  4I04 A;  2DZY A;  3NHE A;  2DJG B;  4QRX A;  2GFO A;  1K3B B;  2G8E A;  4PP2 E;  3TNX A;  3OVZ A;  4P16 A;  1MIR A;  3IFU A;  5CHT A;  2R9N A;  4X6J A;  2OUL A;  2NQD B;  3PBH A;  2CB5 A;  3PDF A;  3QJ3 A;  4OEL A;  5CHV A;  2HH5 A;  5EF4 A;  1POP A;  2YJ8 A;  2G8J A;  2UZJ A;  3BBA A; 
#chains in the Genus database with same CATH homology
 2DJF B;  2R6N A;  3ZUA A;  4HWY A;  2DCA A;  4YYU A;  2DCC A;  5JA7 A;  1U5I A;  2HHN A;  1TLO A;  4RY2 A;  2BDZ A;  1CB5 A;  4GUZ A;  2ATO A;  1W4T A;  2XU1 A;  2DC8 A;  1XKG A;  3CH2 X;  5F02 A;  3OIS A;  2Y6E A;  2DCD A;  1SNK A;  1U9V A;  3V6E A;  2H7J A;  3E1Z B;  3IMA A;  1AU3 A;  1PPO A;  4BSQ A;  1PE6 A;  3LXS A;  1ITO A;  3BOW A;  1KHP A;  1Y08 A;  3C9E A;  4W5B A;  2O6X A;  3D6S A;  4Q8H A;  2FO5 A;  2F7D A;  3MTN A;  1QDQ A;  2P86 A;  1AIM A;  2OZ2 A;  1KFU L;  1KXR A;  4BS5 A;  4MZO A;  4PAD A;  2AYO A;  4YV8 A;  1ZCM A;  3S3Q A;  2FUD A;  2P0R A;  1STF E;  3K24 A;  1SP4 B;  1ME4 A;  1PCI A;  5A24 A;  3MHH A;  2WBF X;  2OP3 A;  5CVM A;  1GMY A;  1W5R A;  1NB5 A;  1QOL A;  1VSN A;  4YYW A;  2ACT A;  3MHS A;  4MZS A;  1AU2 A;  1F2A A;  2AYN A;  4QH6 A;  3MOR A;  4P6E A;  2DC9 A;  4PI3 A;  1AU4 A;  3AI8 A;  2XU4 A;  1BGO A;  3KSE A;  1NQC A;  3KFQ A;  1GX3 A;  2HD5 A;  4KLB A;  4W5C A;  1HUC B;  2AUX A;  4MSX A;  2P7U A;  2Y5B A;  1QXP A;  2B1M A;  3H8C A;  2R9F A;  7PCK A;  4QRG A;  2FTD A;  1NPZ A;  1MHW A;  1E2T A;  3K8U A;  4DMY A;  3PNR A;  4BPV A;  2JQF R;  3RVX A;  4K7C A;  5JH3 A;  3CBK A;  1ZIV A;  2F1G A;  1PXV A;  1YK7 A;  5EGW A;  3HD3 A;  1QMY A;  1EWL A;  2R9O A;  2PNS A;  2XU5 A;  4N4Z A;  4B55 A;  3B79 A;  3N3G A;  1KHQ A;  4BS6 A;  2C0Y A;  3KWB X;  3WXE A;  3O1G A;  2E00 A;  1Y4H A;  1FH0 A;  4CZW A;  4W4U A;  2R9C A;  4BQV A;  1YAL A;  2FRA A;  1F2C A;  2XU3 A;  2YJ2 A;  1GEC E;  3U8E A;  1BP4 A;  3M99 A;  1U9Q X;  1NB3 A;  3CH3 X;  3D9W A;  3QT4 A;  4NV8 A;  1CJL A;  1CV8 A;  1KFX L;  3BCN A;  3N4C A;  2DCB A;  3LTW A;  2YJ9 A;  3USV A;  1U9X A;  2DC7 A;  4DMX A;  2YJC A;  3V6C A;  4X6I A;  1X9Y A;  4QBB A;  4G54 A;  2YJB A;  1YK8 A;  1O0E A;  4N79 A;  4CDC B;  1MEM A;  3H7D A;  1S4V A;  2FYE A;  1JQP A;  4OEM A;  1AU0 A;  3LFY A;  4N8W A;  1ME3 A;  4AXM A;  4FK5 A;  4Q8G A;  1PPN A;  1GCB A;  1YVB A;  2E01 A;  1AYW A;  1F2B A;  1VJV A;  3HHA A;  2FT2 A;  4NV7 A;  3H6S A;  3IEJ A;  1F29 A;  1ICF A;  1PIP A;  1PPP A;  2DZZ A;  4YYR A;  4I07 A;  2NQG A;  4CDE B;  5K16 A;  3P5X A;  3IHP A;  1W6F A;  1AYV A;  3OF8 A;  3P5U A;  3F5V A;  1PBH A;  4XUI A;  1CPJ A;  1MS6 A;  3CBJ A;  1IWD A;  2NQI A;  3DF0 A;  2AUZ A;  1EWM A;  2BSZ A;  3O0U A;  2GHU A;  4WA6 A;  2BDL A;  1Q6K A;  1ATK A;  2G7Y A;  2VFB A;  4I05 A;  1AYU A;  4YVA A;  4FJC A;  3OVX A;  1EWP A;  1CQD A;  2VHS A;  3PW3 A;  3H89 A;  4XR7 A;  6PAD A;  3S3R A;  5PAD A;  4X6H A;  3HWN A;  5CVN B;  5J94 A;  3WXG A;  2E03 A;  4YYS A;  3BPF A;  2IPP B;  2FQ9 A;  3K9M A;  4YYV A;  2AIM A;  3IOQ A;  3HHI A;  4P6G A;  1A6R A;  4FIP A;  1CS8 A;  2ARY A;  3WXF A;  3ERV A;  3KWZ A;  3IV2 A;  1DEU A;  2PRE A;  3BPM A;  2AVW A;  2VHF A;  2JQG R;  3P5V A;  4AXL A;  1CTE A;  4CDD B;  2NQA A;  8PCH A;  3IUT A;  4PP1 A;  1THE A;  2VFC A;  1CVZ A;  3RVW A;  4ZUX U;  2PBH A;  1NLJ A;  1TU6 A;  3I06 A;  3OF9 A;  2CIO A;  1CSB B;  2FRQ A;  5FPW A;  2PAD A;  1EF7 A;  1BQI A;  4QRV A;  3BC3 A;  3KX1 A;  3RVV A;  1EWO A;  3GCB A;  3N3K A;  4C5P A;  1MEG A;  2HXZ A;  1U9W A;  1NL6 A;  1TL9 A;  1YT7 A;  3I3T A;  4CDF B;  2AU1 A;  3QSD A;  1AEC A;  9PAP A;  2DC6 A;  1BY8 A;  4YYQ A;  1GLO A;  2R9M A;  3BWK A;  3H8B A;  3KKU A;  3F75 A;  2IBI A;  1PAD A;  2E02 A;  2G6D A;  5CVO B;  1PPD A;  3P5W A;  1M6D A;  3KW9 A;  2B1N A;  1DF0 A;  2AS8 A;  4I04 A;  2DZY A;  3NHE A;  2DJG B;  4QRX A;  2GFO A;  1K3B B;  2G8E A;  4PP2 E;  3TNX A;  3OVZ A;  4BGF A;  1MIR A;  5CHT A;  2R9N A;  4X6J A;  2OUL A;  2NQD B;  3PBH A;  2CB5 A;  3PDF A;  3QJ3 A;  4OEL A;  5CHV A;  2HH5 A;  5EF4 A;  1POP A;  2YJ8 A;  2G8J A;  1MDW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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