1TL9A

High resolution crystal structure of calpain i protease core in complex with leupeptin
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
321
structure length
321
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords Calpain 1, large [catalytic] subunit
total genus 96
structure length 321
sequence length 321
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2004-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1tl9A02
3CBKA 4QBBA 2DJFB 3BCNA 1AECA 2NQIA 4P6EA 2F7DA 1CV8A 1AYVA 3LXSA 1PPNA 4N4ZA 3PDFA 3RVVA 3OF9A 2C0YA 1MDWA 2R9NA 2AVWA 3KW9A 1F2CA 2XU4A 5J94A 4W4UA 2AIMA 8PCHA 1EWMA 1ATKA 2DCBA 3IEJA 3USVA 1BP4A 3IUTA 4X6JA 4HWYA 1AU0A 1PPPA 3N4CA 1TLOA 1S4VA 1F29A 3H8BA 3H8CA 3KX1A 3HWNA 4XUIA 3E1ZB 2G6DA 2BDZA 3AI8A 3OVXA 4AXMA 1BY8A 4QRGA 2FUDA 2IPPB 2YJ8A 5EF4A 1GCBA 5CHVA 2PADA 1MHWA 1Y4HA 4BQVA 9PAPA 2PREA 3K9MA 2R9OA 2H7JA 4G54A 1XKGA 2HXZA 4XR7A 6PADA 3WXEA 1MS6A 1Q6KA 4BS6A 4ZUXU 1PBHA 1JQPA 2ATOA 2CB5A 3WXFA 1AYUA 1TL9A 1QXPA 1CB5A 3KFQA 4WA6A 2AYNA 1AU2A 4MZSA 1PIPA 1MIRA 2OZ2A 1U9XA 2DCDA 2Y5BA 2FQ9A 2E00A 3B79A 5F02A 1GMYA 1ICFA 4I05A 1PADA 1ME3A 1STFE 2GHUA 2Y6EA 3MHSA 2AU1A 4I07A 1A6RA 4YYUA 5FPWA 2NQDB 2F1GA 4K7CA 1X9YA 2HH5A 2YJ2A 4FIPA 1IWDA 1FH0A 4RY2A 2FO5A 1U5IA 1CPJA 1F2BA 1EWLA 2E01A 5CVMA 3BWKA 4YYRA 4X6HA 3V6CA 3U8EA 4PADA 1CVZA 4X6IA 1NB3A 1VSNA 3D6SA 5EGWA 4YYQA 2B1NA 1GECE 1AU3A 1EWPA 2CIOA 2XU3A 1KXRA 1QOLA 3N3GA 2ARYA 2VHFA 3WXGA 1NQCA 1O0EA 3TNXA 2JQFR 3RVXA 1KFUL 3PW3A 2AYOA 7PCKA 1VJVA 1BQIA 1PCIA 2E02A 3BC3A 1TU6A 2BDLA 3K24A 2DC7A 4CZWA 3IHPA 1PE6A 3M99A 2FT2A 2R6NA 5JH3A 5A24A 4OELA 2DZZA 1PXVA 1THEA 3MHHA 2GFOA 3LFYA 2DZYA 2VHSA 4W5BA 4Q8HA 3IMAA 1SNKA 2P7UA 2DC9A 4W5CA 1CS8A 2B1MA 2FYEA 3N3KA 1YVBA 2IBIA 1YK7A 3H7DA 3QJ3A 4DMXA 3S3RA 2DCAA 4YV8A 1Y08A 3P5VA 1YT7A 2R9CA 3CH3X 2FRQA 4MSXA 2ACTA 1NLJA 4MZOA 4YYVA 4FK5A 3H89A 4P6GA 3OF8A 1SP4B 3MTNA 3I3TA 4Q8GA 3HD3A 3O1GA 3H6SA 4DMYA 2P86A 2G8JA 4AXLA 2FTDA 1GLOA 2AS8A 1K3BB 1ME4A 2DCCA 1U9WA 4CDFB 2P0RA 1DF0A 3HHAA 5PADA 5K16A 1KFXL 2JQGR 1AIMA 4BS5A 4QH6A 2O6XA 2E03A 3OISA 4PP2E 3P5XA 2FRAA 4QRXA 3KWBX 3S3QA 1HUCB 3NHEA 3CH2X 1BGOA 1F2AA 1U9QX 3P5WA 5CHTA 1QMYA 1CJLA 3ZUAA 4OEMA 1POPA 1YALA 3GCBA 5JA7A 2AUXA 2YJ9A 2R9FA 1EWOA 1CTEA 5CVOB 4CDEB 3F75A 3PBHA 2AUZA 1M6DA 5CVNB 1AYWA 3KWZA 2XU1A 3BPFA 1QDQA 1EF7A 1NPZA 2PBHA 3V6EA 1PPOA 1PPDA 4CDCB 2G7YA 2HHNA 2OP3A 2NQAA 3PNRA 4YVAA 1DEUA 2XU5A 1YK8A 3CBJA 2NQGA 2DC6A 1MEGA 4CDDB 3IOQA 3RVWA 3QT4A 3DF0A 2R9MA 3QSDA 4QRVA 2PNSA 4PP1A 2YJBA 4N8WA 1CQDA 3C9EA 2G8EA 3MORA 4FJCA 1AU4A 2HD5A 3BOWA 4BSQA 1MEMA 4PI3A 1U9VA 4BPVA 2YJCA 3IV2A 3ERVA 4YYSA 3P5UA 4N79A 1CSBB 2DC8A 3HHIA 2DJGB 4I04A 3KSEA 1NL6A 1KHQA 1ZIVA 2WBFX 3I06A 4KLBA 1KHPA 3BPMA 3K8UA 2OULA 3KKUA 3F5VA 1NB5A 3OVZA 4YYWA 1ITOA 3O0UA 1ZCMA
chains in the Genus database with same CATH superfamily
3CBKA 4QBBA 3MJ5A 2DJFB 3BCNA 1AECA 2NQIA 4P6EA 2F7DA 1CV8A 1AYVA 3LXSA 1PPNA 4N4ZA 3PDFA 3RVVA 4P16A 3OF9A 2C0YA 1MDWA 4RF1A 2R9NA 3PHUA 2AVWA 3KW9A 1F2CA 2XU4A 4RNAA 5J94A 4BOUA 4W4UA 2AIMA 8PCHA 1EWMA 1ATKA 2DCBA 3IEJA 3USVA 1BP4A 3PRPA 3IUTA 2HWKA 4X6JA 4HWYA 1AU0A 1PPPA 3N4CA 1DKIA 3W31A 4HXDB 4REZA 4RF0A 1TLOA 1S4VA 4MI7A 1F29A 3H8BA 3H8CA 3KX1A 3HWNA 4XUIA 3E1ZB 2G6DA 2BDZA 4A5UA 3AI8A 3OVXA 4AXMA 3OQCA 1BY8A 4QRGA 2FUDA 2IPPB 2YJ8A 4IUMA 5EF4A 1GCBA 5CHVA 2PADA 2FE8A 1PVJA 1MHWA 1Y4HA 4BQVA 9PAPA 2PREA 3K9MA 2R9OA 2H7JA 4G54A 1XKGA 2HXZA 4XR7A 2JTCA 6PADA 3WXEA 1MS6A 4BOQA 1Q6KA 3PRMA 4BS6A 4ZUXU 1PBHA 2BTWB 1JQPA 2ATOA 1UKFA 2CB5A 3WXFA 1AYUA 1TL9A 1QXPA 1CB5A 3KFQA 3BBAA 4WA6A 2AYNA 1AU2A 2JRIA 4MZSA 1PIPA 1MIRA 5EZSA 2OZ2A 1U9XA 2DCDA 2Y5BA 2FQ9A 2E00A 3B79A 5F02A 3PSEA 1GMYA 1ICFA 4I05A 1PADA 1ME3A 1STFE 2GHUA 2Y6EA 3MHSA 2AU1A 4I07A 1A6RA 3E9SA 4YYUA 5FPWA 2NQDB 2F1GA 4K7CA 1X9YA 2HH5A 4BOPA 2YJ2A 4FIPA 1IWDA 1FH0A 4RY2A 2FO5A 1U5IA 1CPJA 1F2BA 1EWLA 2E01A 5CVMA 3BWKA 4YYRA 4X6HA 3V6CA 5KO3A 3U8EA 4PADA 1CVZA 4X6IA 1NB3A 1VSNA 3D6SA 5EGWA 4YYQA 2B1NA 1GECE 1AU3A 1EWPA 3BY4A 2CIOA 2XU3A 3PHWA 1KXRA 1QOLA 3N3GA 4D8IA 2ARYA 2VHFA 3WXGA 1NQCA 1O0EA 3TNXA 2JQFR 3RVXA 1KFUL 3W30A 3PW3A 4MM3B 2AYOA 7PCKA 1VJVA 1BQIA 1PCIA 2E02A 3BC3A 1TU6A 2BDLA 3K24A 2DC7A 4D8BA 4CZWA 3IHPA 1PE6A 3M99A 2FT2A 2R6NA 5JH3A 4OVZA 5A24A 4OELA 3ZNHA 2DZZA 1PXVA 1THEA 3MHHA 2GFOA 3LFYA 5EZQA 2DZYA 2VHSA 4ZTBA 4W5BA 4Q8HA 3IMAA 3MP2A 1SNKA 2P7UA 2DC9A 4OW0A 4W5CA 1CS8A 2B1MA 2FYEA 3N3KA 1YZBA 2BU3A 1YVBA 2IBIA 1YK7A 3H7DA 4XZXA 3QJ3A 4DMXA 3S3RA 2DCAA 4YV8A 1Y08A 3P5VA 5E6JA 1YT7A 2R9CA 3CH3X 2FRQA 4MSXA 2ACTA 1NLJA 4MZOA 4YYVA 4FK5A 2J7QA 3H89A 4P6GA 3TRKA 3OF8A 2AGAA 1SP4B 3MTNA 3I3TA 4Q8GA 3HD3A 3O1GA 3H6SA 4DMYA 2P86A 2G8JA 4AXLA 2FTDA 3O65A 3MTVA 1GLOA 3BB7A 2AS8A 2Z84A 1K3BB 1ME4A 2DCCA 1U9WA 4CDFB 4PT5A 4R3DA 4M0WA 2UZJA 3PT2A 2P0RA 1DF0A 3HHAA 5PADA 5K16A 1KFXL 2JQGR 1AIMA 4BS5A 4QH6A 2O6XA 2E03A 3OISA 4PP2E 3P5XA 2FRAA 4QRXA 3KWBX 3S3QA 1HUCB 3NHEA 3CH2X 3B21A 4IP3A 1BGOA 1F2AA 1U9QX 3P5WA 5CHTA 1QMYA 1CJLA 3ZUAA 4OEMA 3RNVA 1POPA 4GUAA 1YALA 4RKXA 4D8EA 3GCBA 5JA7A 2AUXA 2YJ9A 2R9FA 1EWOA 3C0RA 1CTEA 5CVOB 3TMPA 3PHXA 4CDEB 2J7QC 3F75A 3PBHA 2AUZA 1M6DA 2DOSA 5CVNB 1AYWA 3KWZA 2XU1A 3BPFA 1QDQA 4OVZB 1EF7A 1NPZA 2PBHA 3V6EA 1PPOA 1PPDA 4CDCB 2G7YA 2HHNA 2OP3A 2NQAA 3PNRA 4YVAA 1DEUA 2XU5A 1YK8A 3CBJA 4BOZA 2NQGA 2DC6A 1MEGA 4CDDB 3IOQA 3RVWA 3QT4A 3DF0A 2R9MA 3QSDA 4QRVA 3IFUA 2PNSA 4PP1A 2YJBA 4N8WA 1CQDA 3C9EA 2G8EA 3MORA 4FJCA 1AU4A 2HD5A 3BOWA 4WURA 1MEMA 4PI3A 4BSQA 5JZEA 1U9VA 4BPVA 4BOSA 2YJCA 3IV2A 3ERVA 4YYSA 3P5UA 4N79A 2BTWA 1CSBB 2DC8A 3HHIA 2DJGB 4I04A 3KSEA 1NL6A 1KHQA 1ZIVA 2WBFX 3I06A 4KLBA 1KHPA 3BPMA 3K8UA 2OULA 3KKUA 3F5VA 1NB5A 3OVZA 4YYWA 1ITOA 3O0UA 1ZCMA
chains in the Genus database with same CATH topology
3CBKA 4QBBA 2DJFB 3BCNA 4B55A 1AECA 2NQIA 4P6EA 2F7DA 1CV8A 1AYVA 3LXSA 1PPNA 4N4ZA 3PDFA 3RVVA 3OF9A 2C0YA 1MDWA 2R9NA 2AVWA 3KW9A 4NV8A 1F2CA 2XU4A 5J94A 4W4UA 2AIMA 8PCHA 1EWMA 1ATKA 2DCBA 3IEJA 3USVA 1BP4A 3IUTA 4X6JA 4HWYA 1AU0A 1PPPA 3N4CA 4C5PA 1TLOA 1S4VA 1F29A 3H8BA 3H8CA 3KX1A 3HWNA 4XUIA 3E1ZB 2G6DA 2BDZA 3AI8A 3OVXA 4AXMA 1BY8A 4QRGA 2FUDA 2IPPB 2YJ8A 5EF4A 1GCBA 5CHVA 2PADA 1MHWA 1Y4HA 4BQVA 9PAPA 2PREA 3K9MA 2R9OA 2H7JA 4G54A 1XKGA 2HXZA 4XR7A 6PADA 3WXEA 1MS6A 1Q6KA 4BS6A 4ZUXU 1PBHA 1JQPA 2ATOA 2CB5A 3WXFA 1AYUA 1TL9A 1QXPA 1CB5A 3KFQA 4WA6A 2AYNA 1AU2A 4MZSA 1PIPA 1MIRA 2OZ2A 1U9XA 2DCDA 2Y5BA 2FQ9A 2E00A 3B79A 5F02A 1W6FA 1GMYA 1ICFA 4I05A 1PADA 1ME3A 1STFE 2GHUA 2Y6EA 3MHSA 2AU1A 4I07A 1A6RA 4YYUA 5FPWA 2NQDB 2F1GA 4K7CA 1X9YA 2HH5A 2YJ2A 4FIPA 1IWDA 1FH0A 4RY2A 2FO5A 1U5IA 1CPJA 1F2BA 1EWLA 2E01A 5CVMA 3BWKA 1E2TA 4YYRA 4X6HA 3V6CA 3U8EA 4PADA 1CVZA 4X6IA 1NB3A 1VSNA 3D6SA 5EGWA 4YYQA 2B1NA 1GECE 1AU3A 1EWPA 2CIOA 2XU3A 1KXRA 1QOLA 3N3GA 2ARYA 2VHFA 3WXGA 1NQCA 1O0EA 3TNXA 2JQFR 3RVXA 1KFUL 3PW3A 2AYOA 7PCKA 1VJVA 2BSZA 1BQIA 1PCIA 2E02A 3BC3A 1TU6A 2BDLA 3K24A 2DC7A 4CZWA 3IHPA 1PE6A 3M99A 2FT2A 2R6NA 5JH3A 5A24A 4OELA 2DZZA 1PXVA 1THEA 3MHHA 2GFOA 3LFYA 2DZYA 2VHSA 4GUZA 4W5BA 4Q8HA 3IMAA 1SNKA 2P7UA 2DC9A 4W5CA 1CS8A 2B1MA 2FYEA 3N3KA 1YVBA 2IBIA 1YK7A 3H7DA 3QJ3A 4DMXA 3S3RA 2DCAA 4YV8A 1Y08A 3P5VA 1YT7A 2R9CA 3CH3X 2FRQA 4MSXA 2ACTA 1NLJA 4MZOA 4YYVA 4FK5A 3H89A 4P6GA 3OF8A 1SP4B 3MTNA 3I3TA 4Q8GA 3HD3A 3O1GA 3H6SA 4DMYA 2P86A 2G8JA 4AXLA 2FTDA 1GLOA 2AS8A 1K3BB 1ME4A 2DCCA 1U9WA 4CDFB 2P0RA 1DF0A 3HHAA 5PADA 5K16A 1KFXL 2JQGR 1AIMA 4BS5A 4QH6A 2O6XA 2E03A 3OISA 4PP2E 3P5XA 2FRAA 4QRXA 3KWBX 3S3QA 1HUCB 3NHEA 3CH2X 1BGOA 1F2AA 1U9QX 3P5WA 5CHTA 1QMYA 1CJLA 3ZUAA 4OEMA 1POPA 1YALA 3GCBA 5JA7A 4BGFA 2AUXA 2YJ9A 2R9FA 1EWOA 1CTEA 5CVOB 1W4TA 4CDEB 3F75A 3PBHA 2AUZA 1M6DA 5CVNB 1AYWA 3KWZA 2XU1A 3BPFA 2VFCA 1QDQA 3D9WA 1EF7A 1NPZA 2PBHA 3V6EA 1PPOA 1PPDA 4CDCB 2G7YA 2HHNA 2OP3A 2NQAA 3PNRA 4YVAA 1DEUA 2XU5A 1YK8A 3CBJA 2NQGA 2DC6A 1MEGA 4CDDB 3IOQA 3RVWA 3QT4A 3DF0A 2R9MA 3QSDA 4QRVA 2PNSA 4PP1A 2YJBA 4N8WA 1CQDA 3C9EA 2G8EA 3MORA 4FJCA 1AU4A 2HD5A 3BOWA 4BSQA 1MEMA 4PI3A 1U9VA 4BPVA 2YJCA 3IV2A 3ERVA 1W5RA 3LTWA 4YYSA 3P5UA 4N79A 1CSBB 2DC8A 3HHIA 2DJGB 4I04A 3KSEA 1NL6A 1KHQA 1ZIVA 2WBFX 3I06A 4KLBA 1KHPA 3BPMA 3K8UA 2OULA 3KKUA 3F5VA 1NB5A 4NV7A 3OVZA 2VFBA 4YYWA 1ITOA 3O0UA 1ZCMA 1GX3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CBK A;  4QBB A;  2DJF B;  3BCN A;  1AEC A;  2NQI A;  4P6E A;  2F7D A;  1CV8 A;  1AYV A;  3LXS A;  1PPN A;  4N4Z A;  3PDF A;  3RVV A;  3OF9 A;  2C0Y A;  1MDW A;  2R9N A;  2AVW A;  3KW9 A;  1F2C A;  2XU4 A;  5J94 A;  4W4U A;  2AIM A;  8PCH A;  1EWM A;  1ATK A;  2DCB A;  3IEJ A;  3USV A;  1BP4 A;  3IUT A;  4X6J A;  4HWY A;  1AU0 A;  1PPP A;  3N4C A;  1TLO A;  1S4V A;  1F29 A;  3H8B A;  3H8C A;  3KX1 A;  3HWN A;  4XUI A;  3E1Z B;  2G6D A;  2BDZ A;  3AI8 A;  3OVX A;  4AXM A;  1BY8 A;  4QRG A;  2FUD A;  2IPP B;  2YJ8 A;  5EF4 A;  1GCB A;  5CHV A;  2PAD A;  1MHW A;  1Y4H A;  4BQV A;  9PAP A;  2PRE A;  3K9M A;  2R9O A;  2H7J A;  4G54 A;  1XKG A;  2HXZ A;  4XR7 A;  6PAD A;  3WXE A;  1MS6 A;  1Q6K A;  4BS6 A;  4ZUX U;  1PBH A;  1JQP A;  2ATO A;  2CB5 A;  3WXF A;  1AYU A;  1TL9 A;  1QXP A;  1CB5 A;  3KFQ A;  4WA6 A;  2AYN A;  1AU2 A;  4MZS A;  1PIP A;  1MIR A;  2OZ2 A;  1U9X A;  2DCD A;  2Y5B A;  2FQ9 A;  2E00 A;  3B79 A;  5F02 A;  1GMY A;  1ICF A;  4I05 A;  1PAD A;  1ME3 A;  1STF E;  2GHU A;  2Y6E A;  3MHS A;  2AU1 A;  4I07 A;  1A6R A;  4YYU A;  5FPW A;  2NQD B;  2F1G A;  4K7C A;  1X9Y A;  2HH5 A;  2YJ2 A;  4FIP A;  1IWD A;  1FH0 A;  4RY2 A;  2FO5 A;  1U5I A;  1CPJ A;  1F2B A;  1EWL A;  2E01 A;  5CVM A;  3BWK A;  4YYR A;  4X6H A;  3V6C A;  3U8E A;  4PAD A;  1CVZ A;  4X6I A;  1NB3 A;  1VSN A;  3D6S A;  5EGW A;  4YYQ A;  2B1N A;  1GEC E;  1AU3 A;  1EWP A;  2CIO A;  2XU3 A;  1KXR A;  1QOL A;  3N3G A;  2ARY A;  2VHF A;  3WXG A;  1NQC A;  1O0E A;  3TNX A;  2JQF R;  3RVX A;  1KFU L;  3PW3 A;  2AYO A;  7PCK A;  1VJV A;  1BQI A;  1PCI A;  2E02 A;  3BC3 A;  1TU6 A;  2BDL A;  3K24 A;  2DC7 A;  4CZW A;  3IHP A;  1PE6 A;  3M99 A;  2FT2 A;  2R6N A;  5JH3 A;  5A24 A;  4OEL A;  2DZZ A;  1PXV A;  1THE A;  3MHH A;  2GFO A;  3LFY A;  2DZY A;  2VHS A;  4W5B A;  4Q8H A;  3IMA A;  1SNK A;  2P7U A;  2DC9 A;  4W5C A;  1CS8 A;  2B1M A;  2FYE A;  3N3K A;  1YVB A;  2IBI A;  1YK7 A;  3H7D A;  3QJ3 A;  4DMX A;  3S3R A;  2DCA A;  4YV8 A;  1Y08 A;  3P5V A;  1YT7 A;  2R9C A;  3CH3 X;  2FRQ A;  4MSX A;  2ACT A;  1NLJ A;  4MZO A;  4YYV A;  4FK5 A;  3H89 A;  4P6G A;  3OF8 A;  1SP4 B;  3MTN A;  3I3T A;  4Q8G A;  3HD3 A;  3O1G A;  3H6S A;  4DMY A;  2P86 A;  2G8J A;  4AXL A;  2FTD A;  1GLO A;  2AS8 A;  1K3B B;  1ME4 A;  2DCC A;  1U9W A;  4CDF B;  2P0R A;  1DF0 A;  3HHA A;  5PAD A;  5K16 A;  1KFX L;  2JQG R;  1AIM A;  4BS5 A;  4QH6 A;  2O6X A;  2E03 A;  3OIS A;  4PP2 E;  3P5X A;  2FRA A;  4QRX A;  3KWB X;  3S3Q A;  1HUC B;  3NHE A;  3CH2 X;  1BGO A;  1F2A A;  1U9Q X;  3P5W A;  5CHT A;  1QMY A;  1CJL A;  3ZUA A;  4OEM A;  1POP A;  1YAL A;  3GCB A;  5JA7 A;  2AUX A;  2YJ9 A;  2R9F A;  1EWO A;  1CTE A;  5CVO B;  4CDE B;  3F75 A;  3PBH A;  2AUZ A;  1M6D A;  5CVN B;  1AYW A;  3KWZ A;  2XU1 A;  3BPF A;  1QDQ A;  1EF7 A;  1NPZ A;  2PBH A;  3V6E A;  1PPO A;  1PPD A;  4CDC B;  2G7Y A;  2HHN A;  2OP3 A;  2NQA A;  3PNR A;  4YVA A;  1DEU A;  2XU5 A;  1YK8 A;  3CBJ A;  2NQG A;  2DC6 A;  1MEG A;  4CDD B;  3IOQ A;  3RVW A;  3QT4 A;  3DF0 A;  2R9M A;  3QSD A;  4QRV A;  2PNS A;  4PP1 A;  2YJB A;  4N8W A;  1CQD A;  3C9E A;  2G8E A;  3MOR A;  4FJC A;  1AU4 A;  2HD5 A;  3BOW A;  4BSQ A;  1MEM A;  4PI3 A;  1U9V A;  4BPV A;  2YJC A;  3IV2 A;  3ERV A;  4YYS A;  3P5U A;  4N79 A;  1CSB B;  2DC8 A;  3HHI A;  2DJG B;  4I04 A;  3KSE A;  1NL6 A;  1KHQ A;  1ZIV A;  2WBF X;  3I06 A;  4KLB A;  1KHP A;  3BPM A;  3K8U A;  2OUL A;  3KKU A;  3F5V A;  1NB5 A;  3OVZ A;  4YYW A;  1ITO A;  3O0U A;  1ZCM A; 
#chains in the Genus database with same CATH topology
 3CBK A;  4QBB A;  3MJ5 A;  2DJF B;  3BCN A;  1AEC A;  2NQI A;  4P6E A;  2F7D A;  1CV8 A;  1AYV A;  3LXS A;  1PPN A;  4N4Z A;  3PDF A;  3RVV A;  4P16 A;  3OF9 A;  2C0Y A;  1MDW A;  4RF1 A;  2R9N A;  3PHU A;  2AVW A;  3KW9 A;  1F2C A;  2XU4 A;  4RNA A;  5J94 A;  4BOU A;  4W4U A;  2AIM A;  8PCH A;  1EWM A;  1ATK A;  2DCB A;  3IEJ A;  3USV A;  1BP4 A;  3PRP A;  3IUT A;  2HWK A;  4X6J A;  4HWY A;  1AU0 A;  1PPP A;  3N4C A;  1DKI A;  3W31 A;  4HXD B;  4REZ A;  4RF0 A;  1TLO A;  1S4V A;  4MI7 A;  1F29 A;  3H8B A;  3H8C A;  3KX1 A;  3HWN A;  4XUI A;  3E1Z B;  2G6D A;  2BDZ A;  4A5U A;  3AI8 A;  3OVX A;  4AXM A;  3OQC A;  1BY8 A;  4QRG A;  2FUD A;  2IPP B;  2YJ8 A;  4IUM A;  5EF4 A;  1GCB A;  5CHV A;  2PAD A;  2FE8 A;  1PVJ A;  1MHW A;  1Y4H A;  4BQV A;  9PAP A;  2PRE A;  3K9M A;  2R9O A;  2H7J A;  4G54 A;  1XKG A;  2HXZ A;  4XR7 A;  2JTC A;  6PAD A;  3WXE A;  1MS6 A;  4BOQ A;  1Q6K A;  3PRM A;  4BS6 A;  4ZUX U;  1PBH A;  2BTW B;  1JQP A;  2ATO A;  1UKF A;  2CB5 A;  3WXF A;  1AYU A;  1TL9 A;  1QXP A;  1CB5 A;  3KFQ A;  3BBA A;  4WA6 A;  2AYN A;  1AU2 A;  2JRI A;  4MZS A;  1PIP A;  1MIR A;  5EZS A;  2OZ2 A;  1U9X A;  2DCD A;  2Y5B A;  2FQ9 A;  2E00 A;  3B79 A;  5F02 A;  3PSE A;  1GMY A;  1ICF A;  4I05 A;  1PAD A;  1ME3 A;  1STF E;  2GHU A;  2Y6E A;  3MHS A;  2AU1 A;  4I07 A;  1A6R A;  3E9S A;  4YYU A;  5FPW A;  2NQD B;  2F1G A;  4K7C A;  1X9Y A;  2HH5 A;  4BOP A;  2YJ2 A;  4FIP A;  1IWD A;  1FH0 A;  4RY2 A;  2FO5 A;  1U5I A;  1CPJ A;  1F2B A;  1EWL A;  2E01 A;  5CVM A;  3BWK A;  4YYR A;  4X6H A;  3V6C A;  5KO3 A;  3U8E A;  4PAD A;  1CVZ A;  4X6I A;  1NB3 A;  1VSN A;  3D6S A;  5EGW A;  4YYQ A;  2B1N A;  1GEC E;  1AU3 A;  1EWP A;  3BY4 A;  2CIO A;  2XU3 A;  3PHW A;  1KXR A;  1QOL A;  3N3G A;  4D8I A;  2ARY A;  2VHF A;  3WXG A;  1NQC A;  1O0E A;  3TNX A;  2JQF R;  3RVX A;  1KFU L;  3W30 A;  3PW3 A;  4MM3 B;  2AYO A;  7PCK A;  1VJV A;  1BQI A;  1PCI A;  2E02 A;  3BC3 A;  1TU6 A;  2BDL A;  3K24 A;  2DC7 A;  4D8B A;  4CZW A;  3IHP A;  1PE6 A;  3M99 A;  2FT2 A;  2R6N A;  5JH3 A;  4OVZ A;  5A24 A;  4OEL A;  3ZNH A;  2DZZ A;  1PXV A;  1THE A;  3MHH A;  2GFO A;  3LFY A;  5EZQ A;  2DZY A;  2VHS A;  4ZTB A;  4W5B A;  4Q8H A;  3IMA A;  3MP2 A;  1SNK A;  2P7U A;  2DC9 A;  4OW0 A;  4W5C A;  1CS8 A;  2B1M A;  2FYE A;  3N3K A;  1YZB A;  2BU3 A;  1YVB A;  2IBI A;  1YK7 A;  3H7D A;  4XZX A;  3QJ3 A;  4DMX A;  3S3R A;  2DCA A;  4YV8 A;  1Y08 A;  3P5V A;  5E6J A;  1YT7 A;  2R9C A;  3CH3 X;  2FRQ A;  4MSX A;  2ACT A;  1NLJ A;  4MZO A;  4YYV A;  4FK5 A;  2J7Q A;  3H89 A;  4P6G A;  3TRK A;  3OF8 A;  2AGA A;  1SP4 B;  3MTN A;  3I3T A;  4Q8G A;  3HD3 A;  3O1G A;  3H6S A;  4DMY A;  2P86 A;  2G8J A;  4AXL A;  2FTD A;  3O65 A;  3MTV A;  1GLO A;  3BB7 A;  2AS8 A;  2Z84 A;  1K3B B;  1ME4 A;  2DCC A;  1U9W A;  4CDF B;  4PT5 A;  4R3D A;  4M0W A;  2UZJ A;  3PT2 A;  2P0R A;  1DF0 A;  3HHA A;  5PAD A;  5K16 A;  1KFX L;  2JQG R;  1AIM A;  4BS5 A;  4QH6 A;  2O6X A;  2E03 A;  3OIS A;  4PP2 E;  3P5X A;  2FRA A;  4QRX A;  3KWB X;  3S3Q A;  1HUC B;  3NHE A;  3CH2 X;  3B21 A;  4IP3 A;  1BGO A;  1F2A A;  1U9Q X;  3P5W A;  5CHT A;  1QMY A;  1CJL A;  3ZUA A;  4OEM A;  3RNV A;  1POP A;  4GUA A;  1YAL A;  4RKX A;  4D8E A;  3GCB A;  5JA7 A;  2AUX A;  2YJ9 A;  2R9F A;  1EWO A;  3C0R A;  1CTE A;  5CVO B;  3TMP A;  3PHX A;  4CDE B;  2J7Q C;  3F75 A;  3PBH A;  2AUZ A;  1M6D A;  2DOS A;  5CVN B;  1AYW A;  3KWZ A;  2XU1 A;  3BPF A;  1QDQ A;  4OVZ B;  1EF7 A;  1NPZ A;  2PBH A;  3V6E A;  1PPO A;  1PPD A;  4CDC B;  2G7Y A;  2HHN A;  2OP3 A;  2NQA A;  3PNR A;  4YVA A;  1DEU A;  2XU5 A;  1YK8 A;  3CBJ A;  4BOZ A;  2NQG A;  2DC6 A;  1MEG A;  4CDD B;  3IOQ A;  3RVW A;  3QT4 A;  3DF0 A;  2R9M A;  3QSD A;  4QRV A;  3IFU A;  2PNS A;  4PP1 A;  2YJB A;  4N8W A;  1CQD A;  3C9E A;  2G8E A;  3MOR A;  4FJC A;  1AU4 A;  2HD5 A;  3BOW A;  4WUR A;  1MEM A;  4PI3 A;  4BSQ A;  5JZE A;  1U9V A;  4BPV A;  4BOS A;  2YJC A;  3IV2 A;  3ERV A;  4YYS A;  3P5U A;  4N79 A;  2BTW A;  1CSB B;  2DC8 A;  3HHI A;  2DJG B;  4I04 A;  3KSE A;  1NL6 A;  1KHQ A;  1ZIV A;  2WBF X;  3I06 A;  4KLB A;  1KHP A;  3BPM A;  3K8U A;  2OUL A;  3KKU A;  3F5V A;  1NB5 A;  3OVZ A;  4YYW A;  1ITO A;  3O0U A;  1ZCM A; 
#chains in the Genus database with same CATH homology
 3CBK A;  4QBB A;  2DJF B;  3BCN A;  4B55 A;  1AEC A;  2NQI A;  4P6E A;  2F7D A;  1CV8 A;  1AYV A;  3LXS A;  1PPN A;  4N4Z A;  3PDF A;  3RVV A;  3OF9 A;  2C0Y A;  1MDW A;  2R9N A;  2AVW A;  3KW9 A;  4NV8 A;  1F2C A;  2XU4 A;  5J94 A;  4W4U A;  2AIM A;  8PCH A;  1EWM A;  1ATK A;  2DCB A;  3IEJ A;  3USV A;  1BP4 A;  3IUT A;  4X6J A;  4HWY A;  1AU0 A;  1PPP A;  3N4C A;  4C5P A;  1TLO A;  1S4V A;  1F29 A;  3H8B A;  3H8C A;  3KX1 A;  3HWN A;  4XUI A;  3E1Z B;  2G6D A;  2BDZ A;  3AI8 A;  3OVX A;  4AXM A;  1BY8 A;  4QRG A;  2FUD A;  2IPP B;  2YJ8 A;  5EF4 A;  1GCB A;  5CHV A;  2PAD A;  1MHW A;  1Y4H A;  4BQV A;  9PAP A;  2PRE A;  3K9M A;  2R9O A;  2H7J A;  4G54 A;  1XKG A;  2HXZ A;  4XR7 A;  6PAD A;  3WXE A;  1MS6 A;  1Q6K A;  4BS6 A;  4ZUX U;  1PBH A;  1JQP A;  2ATO A;  2CB5 A;  3WXF A;  1AYU A;  1TL9 A;  1QXP A;  1CB5 A;  3KFQ A;  4WA6 A;  2AYN A;  1AU2 A;  4MZS A;  1PIP A;  1MIR A;  2OZ2 A;  1U9X A;  2DCD A;  2Y5B A;  2FQ9 A;  2E00 A;  3B79 A;  5F02 A;  1W6F A;  1GMY A;  1ICF A;  4I05 A;  1PAD A;  1ME3 A;  1STF E;  2GHU A;  2Y6E A;  3MHS A;  2AU1 A;  4I07 A;  1A6R A;  4YYU A;  5FPW A;  2NQD B;  2F1G A;  4K7C A;  1X9Y A;  2HH5 A;  2YJ2 A;  4FIP A;  1IWD A;  1FH0 A;  4RY2 A;  2FO5 A;  1U5I A;  1CPJ A;  1F2B A;  1EWL A;  2E01 A;  5CVM A;  3BWK A;  1E2T A;  4YYR A;  4X6H A;  3V6C A;  3U8E A;  4PAD A;  1CVZ A;  4X6I A;  1NB3 A;  1VSN A;  3D6S A;  5EGW A;  4YYQ A;  2B1N A;  1GEC E;  1AU3 A;  1EWP A;  2CIO A;  2XU3 A;  1KXR A;  1QOL A;  3N3G A;  2ARY A;  2VHF A;  3WXG A;  1NQC A;  1O0E A;  3TNX A;  2JQF R;  3RVX A;  1KFU L;  3PW3 A;  2AYO A;  7PCK A;  1VJV A;  2BSZ A;  1BQI A;  1PCI A;  2E02 A;  3BC3 A;  1TU6 A;  2BDL A;  3K24 A;  2DC7 A;  4CZW A;  3IHP A;  1PE6 A;  3M99 A;  2FT2 A;  2R6N A;  5JH3 A;  5A24 A;  4OEL A;  2DZZ A;  1PXV A;  1THE A;  3MHH A;  2GFO A;  3LFY A;  2DZY A;  2VHS A;  4GUZ A;  4W5B A;  4Q8H A;  3IMA A;  1SNK A;  2P7U A;  2DC9 A;  4W5C A;  1CS8 A;  2B1M A;  2FYE A;  3N3K A;  1YVB A;  2IBI A;  1YK7 A;  3H7D A;  3QJ3 A;  4DMX A;  3S3R A;  2DCA A;  4YV8 A;  1Y08 A;  3P5V A;  1YT7 A;  2R9C A;  3CH3 X;  2FRQ A;  4MSX A;  2ACT A;  1NLJ A;  4MZO A;  4YYV A;  4FK5 A;  3H89 A;  4P6G A;  3OF8 A;  1SP4 B;  3MTN A;  3I3T A;  4Q8G A;  3HD3 A;  3O1G A;  3H6S A;  4DMY A;  2P86 A;  2G8J A;  4AXL A;  2FTD A;  1GLO A;  2AS8 A;  1K3B B;  1ME4 A;  2DCC A;  1U9W A;  4CDF B;  2P0R A;  1DF0 A;  3HHA A;  5PAD A;  5K16 A;  1KFX L;  2JQG R;  1AIM A;  4BS5 A;  4QH6 A;  2O6X A;  2E03 A;  3OIS A;  4PP2 E;  3P5X A;  2FRA A;  4QRX A;  3KWB X;  3S3Q A;  1HUC B;  3NHE A;  3CH2 X;  1BGO A;  1F2A A;  1U9Q X;  3P5W A;  5CHT A;  1QMY A;  1CJL A;  3ZUA A;  4OEM A;  1POP A;  1YAL A;  3GCB A;  5JA7 A;  4BGF A;  2AUX A;  2YJ9 A;  2R9F A;  1EWO A;  1CTE A;  5CVO B;  1W4T A;  4CDE B;  3F75 A;  3PBH A;  2AUZ A;  1M6D A;  5CVN B;  1AYW A;  3KWZ A;  2XU1 A;  3BPF A;  2VFC A;  1QDQ A;  3D9W A;  1EF7 A;  1NPZ A;  2PBH A;  3V6E A;  1PPO A;  1PPD A;  4CDC B;  2G7Y A;  2HHN A;  2OP3 A;  2NQA A;  3PNR A;  4YVA A;  1DEU A;  2XU5 A;  1YK8 A;  3CBJ A;  2NQG A;  2DC6 A;  1MEG A;  4CDD B;  3IOQ A;  3RVW A;  3QT4 A;  3DF0 A;  2R9M A;  3QSD A;  4QRV A;  2PNS A;  4PP1 A;  2YJB A;  4N8W A;  1CQD A;  3C9E A;  2G8E A;  3MOR A;  4FJC A;  1AU4 A;  2HD5 A;  3BOW A;  4BSQ A;  1MEM A;  4PI3 A;  1U9V A;  4BPV A;  2YJC A;  3IV2 A;  3ERV A;  1W5R A;  3LTW A;  4YYS A;  3P5U A;  4N79 A;  1CSB B;  2DC8 A;  3HHI A;  2DJG B;  4I04 A;  3KSE A;  1NL6 A;  1KHQ A;  1ZIV A;  2WBF X;  3I06 A;  4KLB A;  1KHP A;  3BPM A;  3K8U A;  2OUL A;  3KKU A;  3F5V A;  1NB5 A;  4NV7 A;  3OVZ A;  2VFB A;  4YYW A;  1ITO A;  3O0U A;  1ZCM A;  1GX3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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