1U9VA

Crystal structure of the cysteine protease human cathepsin k in complex with the covalent inhibitor nvp-abe854
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 62
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2004-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1u9vA00
1U5IA 3BPMA 1YALA 5JA7A 1MDWA 2OZ2A 3DF0A 3TNXA 3IHPA 1CSBB 1PPDA 2XU3A 3ZUAA 2XU5A 3CH3X 1GECE 2G7YA 1ME3A 4QH6A 1QDQA 2YJ2A 1NQCA 4YV8A 1TU6A 3OVXA 5JH3A 2FRAA 2E00A 4MSXA 2P0RA 3PW3A 5K16A 1TL9A 5CVOB 3BWKA 1MEMA 4W4UA 3IUTA 1S4VA 2NQAA 3H6SA 4YYSA 5CVMA 3C9EA 2IPPB 3IV2A 4PP1A 3K9MA 1A6RA 4MZOA 3IOQA 5CHTA 1BGOA 2PREA 4KLBA 4FJCA 5PADA 1NPZA 4MZSA 3KW9A 2Y6EA 2Y5BA 1MEGA 1U9QX 5EF4A 1AU4A 2DCAA 3N4CA 3BCNA 1F29A 1Y08A 4YYQA 2AIMA 1NLJA 1NB3A 2DJGB 4BS6A 1F2AA 3BOWA 4Q8HA 3LFYA 3H8CA 2DJFB 2ACTA 2HD5A 3B79A 3KSEA 2DZZA 1THEA 1AIMA 1GLOA 4AXLA 1CQDA 1CVZA 5F02A 2FT2A 3HHAA 3KWZA 1PADA 1KFXL 4YVAA 1AYUA 1PE6A 8PCHA 2AUXA 4ZUXU 1CS8A 1YK7A 2JQFR 9PAPA 3P5WA 1M6DA 3F75A 3HHIA 1YVBA 2G8JA 1F2CA 1PIPA 2DC9A 2JQGR 5CVNB 1ITOA 1KHQA 4K7CA 2ATOA 1NB5A 5J94A 3KKUA 2FUDA 2G8EA 3LXSA 4QRXA 4XUIA 2E02A 2YJBA 3KWBX 5CHVA 2E01A 3H7DA 3F5VA 3HD3A 1KFUL 2FTDA 2E03A 4N4ZA 2IBIA 4YYVA 1U9VA 1CV8A 1DEUA 1PPNA 2GHUA 2PADA 4QRGA 3S3QA 1AU2A 1TLOA 3V6CA 3OF9A 3QSDA 3P5XA 4FK5A 1Y4HA 1VJVA 3WXEA 1ATKA 4YYRA 3H8BA 1PPOA 2AYNA 2AUZA 1EWPA 2R9CA 3O0UA 1ZIVA 2HXZA 1GMYA 5FPWA 2P86A 2F1GA 3O1GA 3V6EA 2AVWA 1CTEA 4BS5A 1U9WA 3P5UA 2BDZA 1QXPA 1PBHA 3PNRA 2AU1A 2DC8A 4QBBA 1GCBA 3D6SA 3N3GA 2R9OA 2HH5A 1MS6A 3RVXA 1SP4B 1CJLA 3QT4A 2C0YA 4X6HA 3MORA 1STFE 2AYOA 2DCCA 3BPFA 4WA6A 3NHEA 3CH2X 1EWMA 3GCBA 2PBHA 3OVZA 1YT7A 2WBFX 3MTNA 4Q8GA 4P6EA 3H89A 3I3TA 1EWLA 1K3BB 4G54A 4CDEB 1F2BA 1AU0A 2XU4A 1X9YA 1CB5A 4N8WA 1BQIA 2B1NA 2R9NA 4X6IA 4CZWA 4CDFB 4RY2A 3N3KA 1U9XA 2CIOA 4AXMA 3OISA 4W5BA 1XKGA 2CB5A 4X6JA 3QJ3A 1SNKA 1QMYA 2B1MA 2HHNA 2NQDB 2DC7A 7PCKA 1EF7A 1HUCB 4PP2E 1FH0A 3MHHA 3CBKA 3RVWA 2VHSA 2FRQA 2P7UA 1ME4A 3PDFA 2YJ8A 4P6GA 3RVVA 4OELA 4FIPA 2VHFA 1PXVA 2OULA 2ARYA 3K24A 3KFQA 3PBHA 3IMAA 1AYVA 3ERVA 1AECA 4DMXA 3WXFA 2FYEA 1QOLA 3USVA 2H7JA 2NQGA 1ICFA 4PI3A 3M99A 2O6XA 4OEMA 2YJ9A 2DZYA 2DCBA 4N79A 5EGWA 2PNSA 3KX1A 2XU1A 1AU3A 4CDCB 3CBJA 1PCIA 4CDDB 4BQVA 1ZCMA 2AS8A 2GFOA 1IWDA 3I06A 1BP4A 4YYWA 4BPVA 2R6NA 3S3RA 1Q6KA 2DCDA 1VSNA 2R9FA 3WXGA 1MIRA 1JQPA 3K8UA 2FO5A 4DMYA 1DF0A 3MHSA 2F7DA 2BDLA 4XR7A 1CPJA 1EWOA 2FQ9A 3BC3A 6PADA 3OF8A 4QRVA 4PADA 2R9MA 4BSQA 1KXRA 3U8EA 4YYUA 1O0EA 2NQIA 4W5CA 4I04A 1MHWA 1KHPA 3IEJA 2YJCA 3P5VA 4I07A 2DC6A 1PPPA 1AYWA 3HWNA 4I05A 2OP3A 1POPA 4HWYA 3AI8A 5A24A 1YK8A 2G6DA 1BY8A 3E1ZB 1NL6A
chains in the Genus database with same CATH superfamily
1U5IA 3PT2A 3TMPA 3BPMA 3RNVA 1YALA 5JA7A 1MDWA 2OZ2A 3DF0A 3TNXA 3IHPA 1CSBB 1PPDA 2XU3A 3ZUAA 2XU5A 3CH3X 1GECE 2G7YA 4M0WA 1ME3A 3PRMA 4PT5A 4QH6A 2UZJA 4BOSA 1QDQA 4D8IA 2YJ2A 1NQCA 4YV8A 1TU6A 3OVXA 5JH3A 2FRAA 2E00A 4MSXA 2P0RA 3PW3A 5K16A 1TL9A 4RF1A 5CVOB 3BWKA 4D8EA 1MEMA 4RKXA 3MTVA 4W4UA 3IUTA 1S4VA 2NQAA 3W30A 3H6SA 4YYSA 5CVMA 3C9EA 2IPPB 3IV2A 4PP1A 3K9MA 1A6RA 4MZOA 3IOQA 5CHTA 3PSEA 1BGOA 2PREA 4KLBA 4FJCA 5PADA 1NPZA 4MZSA 5EZQA 3KW9A 2Y6EA 2Y5BA 1MEGA 1U9QX 5EF4A 3PRPA 1AU4A 2DCAA 3N4CA 3BCNA 1F29A 1Y08A 4IP3A 4YYQA 2AIMA 1NLJA 1NB3A 1PVJA 2DJGB 4BS6A 1F2AA 3BOWA 4Q8HA 3LFYA 4OVZA 3H8CA 2DJFB 2ACTA 2HD5A 3B79A 3KSEA 2DZZA 1THEA 1AIMA 1GLOA 4AXLA 1CQDA 3PHUA 1CVZA 5F02A 4BOQA 2FT2A 3HHAA 3KWZA 1PADA 1KFXL 4WURA 4YVAA 1AYUA 1PE6A 5JZEA 8PCHA 2AUXA 4ZUXU 1CS8A 1UKFA 1YK7A 2JQFR 9PAPA 3P5WA 1M6DA 3F75A 3HHIA 1YVBA 3E9SA 2G8JA 1F2CA 1PIPA 2DC9A 2JQGR 2BTWB 5CVNB 1ITOA 1KHQA 4HXDB 4K7CA 2ATOA 1NB5A 3B21A 5J94A 3KKUA 2FUDA 2G8EA 5E6JA 3LXSA 4QRXA 4XUIA 2E02A 2YJBA 3KWBX 5CHVA 2E01A 3H7DA 3F5VA 4IUMA 3BB7A 3HD3A 1KFUL 2FTDA 4MM3B 2E03A 4N4ZA 2IBIA 4YYVA 1U9VA 1CV8A 1DEUA 1PPNA 2GHUA 2PADA 4QRGA 3S3QA 1AU2A 1TLOA 3V6CA 3OF9A 3QSDA 3P5XA 4FK5A 1Y4HA 4RF0A 1VJVA 5EZSA 3BBAA 3WXEA 1ATKA 4YYRA 3H8BA 1PPOA 2AYNA 2AUZA 3BY4A 1EWPA 2R9CA 3O0UA 1ZIVA 4GUAA 2HXZA 1GMYA 5FPWA 2P86A 2F1GA 4MI7A 3O1GA 5KO3A 3V6EA 2AVWA 1CTEA 4BS5A 1U9WA 3P5UA 2BDZA 1QXPA 2BU3A 3IFUA 4REZA 4BOZA 1PBHA 3PNRA 2AU1A 2DC8A 4QBBA 1GCBA 3D6SA 3N3GA 2R9OA 2HH5A 1MS6A 3RVXA 1SP4B 1CJLA 3QT4A 2C0YA 4X6HA 2FE8A 3MORA 1STFE 2AYOA 2DCCA 3BPFA 4WA6A 3NHEA 3CH2X 1EWMA 3GCBA 2PBHA 3OVZA 1YT7A 2WBFX 3MTNA 4RNAA 4Q8GA 4P6EA 3H89A 3I3TA 1EWLA 1K3BB 4G54A 4CDEB 1F2BA 1AU0A 2XU4A 1X9YA 1CB5A 4N8WA 1BQIA 2B1NA 2R9NA 4X6IA 4CZWA 2DOSA 4CDFB 4RY2A 3N3KA 1U9XA 2CIOA 4AXMA 4A5UA 3OISA 4W5BA 1XKGA 4BOUA 2CB5A 4X6JA 3QJ3A 1SNKA 1QMYA 2B1MA 2HHNA 2NQDB 3PHWA 2DC7A 7PCKA 1EF7A 1HUCB 3ZNHA 4PP2E 3MP2A 1FH0A 3MHHA 3CBKA 3RVWA 2VHSA 2FRQA 2P7UA 1ME4A 3PDFA 2YJ8A 4P6GA 3RVVA 2JTCA 4OELA 2BTWA 3W31A 4FIPA 2VHFA 1PXVA 2OULA 2ARYA 3K24A 4ZTBA 2J7QC 3KFQA 3PBHA 3IMAA 1AYVA 2Z84A 3ERVA 1AECA 4DMXA 3WXFA 2FYEA 1QOLA 3USVA 2H7JA 2NQGA 1ICFA 4D8BA 4PI3A 3M99A 2O6XA 4OEMA 2YJ9A 2DZYA 2DCBA 4N79A 5EGWA 2PNSA 3KX1A 2XU1A 1AU3A 4CDCB 3CBJA 1PCIA 4OVZB 4CDDB 4BQVA 1ZCMA 3C0RA 2AS8A 2GFOA 3PHXA 1IWDA 3I06A 4BOPA 1BP4A 4YYWA 4XZXA 4BPVA 2R6NA 3S3RA 1Q6KA 2DCDA 1VSNA 2R9FA 1YZBA 3WXGA 1MIRA 1JQPA 2AGAA 2HWKA 3K8UA 2FO5A 4DMYA 1DF0A 3MHSA 2F7DA 2BDLA 4XR7A 1CPJA 1EWOA 2FQ9A 3BC3A 6PADA 3OF8A 4QRVA 4PADA 4P16A 2R9MA 4BSQA 1KXRA 3U8EA 4YYUA 1O0EA 2JRIA 2NQIA 3O65A 3TRKA 4W5CA 4I04A 1MHWA 1KHPA 4R3DA 3IEJA 3OQCA 2YJCA 3P5VA 4I07A 3MJ5A 2DC6A 1PPPA 1AYWA 3HWNA 4I05A 2OP3A 1POPA 4OW0A 4HWYA 3AI8A 5A24A 1YK8A 2G6DA 1DKIA 1BY8A 3E1ZB 1NL6A 2J7QA
chains in the Genus database with same CATH topology
1U5IA 4B55A 3BPMA 1YALA 5JA7A 1MDWA 2OZ2A 3DF0A 3TNXA 3IHPA 4NV7A 1CSBB 1PPDA 2XU3A 3ZUAA 2XU5A 3CH3X 1GECE 2G7YA 1ME3A 4BGFA 4QH6A 1QDQA 2YJ2A 1NQCA 4YV8A 1TU6A 3OVXA 4GUZA 5JH3A 2FRAA 2E00A 4MSXA 2P0RA 3PW3A 5K16A 1TL9A 5CVOB 3BWKA 1MEMA 4W4UA 2VFBA 3IUTA 1S4VA 2NQAA 3H6SA 4YYSA 5CVMA 3C9EA 2IPPB 3IV2A 4PP1A 3K9MA 1A6RA 4MZOA 3IOQA 4NV8A 5CHTA 1BGOA 2PREA 4KLBA 4FJCA 5PADA 1NPZA 4MZSA 3KW9A 2Y6EA 2Y5BA 1W5RA 1MEGA 1U9QX 5EF4A 1AU4A 2DCAA 3N4CA 3BCNA 1F29A 1Y08A 4YYQA 2AIMA 1NLJA 1NB3A 2DJGB 4BS6A 1F2AA 3BOWA 4Q8HA 3LFYA 3H8CA 2DJFB 2ACTA 2HD5A 3B79A 3KSEA 2DZZA 1THEA 1AIMA 1GLOA 4AXLA 1CQDA 1CVZA 5F02A 2FT2A 3HHAA 3KWZA 1PADA 1KFXL 4YVAA 1AYUA 1PE6A 4C5PA 8PCHA 2AUXA 4ZUXU 1CS8A 1YK7A 2JQFR 9PAPA 3P5WA 1M6DA 3F75A 3HHIA 1YVBA 2G8JA 1F2CA 1PIPA 2DC9A 2JQGR 5CVNB 1ITOA 1KHQA 4K7CA 2ATOA 1NB5A 5J94A 3KKUA 2FUDA 2G8EA 3LXSA 4QRXA 4XUIA 2E02A 2YJBA 3KWBX 5CHVA 2E01A 3H7DA 3F5VA 3HD3A 1KFUL 2FTDA 2E03A 4N4ZA 2IBIA 4YYVA 1U9VA 1CV8A 1DEUA 1PPNA 2GHUA 2PADA 4QRGA 3S3QA 1AU2A 1TLOA 3V6CA 3OF9A 3QSDA 3P5XA 4FK5A 1Y4HA 1VJVA 3WXEA 1ATKA 4YYRA 3H8BA 1PPOA 2AYNA 2AUZA 1EWPA 2R9CA 3O0UA 1ZIVA 2HXZA 1GMYA 5FPWA 2P86A 2F1GA 3O1GA 3V6EA 2AVWA 1CTEA 4BS5A 1U9WA 3P5UA 2BDZA 1QXPA 1PBHA 3PNRA 2AU1A 2DC8A 4QBBA 1GCBA 3D6SA 3N3GA 2R9OA 2HH5A 1MS6A 3RVXA 1SP4B 1CJLA 3QT4A 2C0YA 4X6HA 3MORA 1STFE 2AYOA 2DCCA 3BPFA 4WA6A 3NHEA 3CH2X 1EWMA 3GCBA 2PBHA 3OVZA 1YT7A 2WBFX 3MTNA 4Q8GA 4P6EA 3H89A 3I3TA 1EWLA 1K3BB 4G54A 4CDEB 1F2BA 1AU0A 1W6FA 2XU4A 1X9YA 1CB5A 4N8WA 1BQIA 2B1NA 2R9NA 4X6IA 4CZWA 4CDFB 4RY2A 1E2TA 3N3KA 1U9XA 2CIOA 4AXMA 3OISA 4W5BA 1XKGA 2CB5A 4X6JA 3QJ3A 1SNKA 1QMYA 2B1MA 2HHNA 2NQDB 2DC7A 7PCKA 1EF7A 1HUCB 4PP2E 1FH0A 3MHHA 3CBKA 3RVWA 2VHSA 2FRQA 2P7UA 1ME4A 3PDFA 2YJ8A 4P6GA 3RVVA 4OELA 4FIPA 2VHFA 1PXVA 2OULA 2ARYA 3K24A 3KFQA 3PBHA 3IMAA 1AYVA 1W4TA 3ERVA 1AECA 4DMXA 3WXFA 2FYEA 1QOLA 3USVA 2H7JA 2NQGA 1ICFA 4PI3A 3M99A 2O6XA 4OEMA 2YJ9A 2DZYA 2DCBA 4N79A 5EGWA 2PNSA 3KX1A 2XU1A 1AU3A 2VFCA 2BSZA 4CDCB 3CBJA 1PCIA 4CDDB 4BQVA 1ZCMA 2AS8A 2GFOA 1IWDA 3I06A 1BP4A 4YYWA 4BPVA 2R6NA 3S3RA 1Q6KA 2DCDA 1VSNA 2R9FA 3WXGA 1MIRA 1JQPA 3K8UA 2FO5A 4DMYA 1DF0A 3MHSA 2F7DA 2BDLA 4XR7A 1CPJA 1EWOA 2FQ9A 3BC3A 6PADA 3OF8A 4QRVA 4PADA 2R9MA 4BSQA 1KXRA 3U8EA 1GX3A 4YYUA 1O0EA 3LTWA 2NQIA 4W5CA 4I04A 1MHWA 1KHPA 3D9WA 3IEJA 2YJCA 3P5VA 4I07A 2DC6A 1PPPA 1AYWA 3HWNA 4I05A 2OP3A 1POPA 4HWYA 3AI8A 5A24A 1YK8A 2G6DA 1BY8A 3E1ZB 1NL6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U5I A;  3BPM A;  1YAL A;  5JA7 A;  1MDW A;  2OZ2 A;  3DF0 A;  3TNX A;  3IHP A;  1CSB B;  1PPD A;  2XU3 A;  3ZUA A;  2XU5 A;  3CH3 X;  1GEC E;  2G7Y A;  1ME3 A;  4QH6 A;  1QDQ A;  2YJ2 A;  1NQC A;  4YV8 A;  1TU6 A;  3OVX A;  5JH3 A;  2FRA A;  2E00 A;  4MSX A;  2P0R A;  3PW3 A;  5K16 A;  1TL9 A;  5CVO B;  3BWK A;  1MEM A;  4W4U A;  3IUT A;  1S4V A;  2NQA A;  3H6S A;  4YYS A;  5CVM A;  3C9E A;  2IPP B;  3IV2 A;  4PP1 A;  3K9M A;  1A6R A;  4MZO A;  3IOQ A;  5CHT A;  1BGO A;  2PRE A;  4KLB A;  4FJC A;  5PAD A;  1NPZ A;  4MZS A;  3KW9 A;  2Y6E A;  2Y5B A;  1MEG A;  1U9Q X;  5EF4 A;  1AU4 A;  2DCA A;  3N4C A;  3BCN A;  1F29 A;  1Y08 A;  4YYQ A;  2AIM A;  1NLJ A;  1NB3 A;  2DJG B;  4BS6 A;  1F2A A;  3BOW A;  4Q8H A;  3LFY A;  3H8C A;  2DJF B;  2ACT A;  2HD5 A;  3B79 A;  3KSE A;  2DZZ A;  1THE A;  1AIM A;  1GLO A;  4AXL A;  1CQD A;  1CVZ A;  5F02 A;  2FT2 A;  3HHA A;  3KWZ A;  1PAD A;  1KFX L;  4YVA A;  1AYU A;  1PE6 A;  8PCH A;  2AUX A;  4ZUX U;  1CS8 A;  1YK7 A;  2JQF R;  9PAP A;  3P5W A;  1M6D A;  3F75 A;  3HHI A;  1YVB A;  2G8J A;  1F2C A;  1PIP A;  2DC9 A;  2JQG R;  5CVN B;  1ITO A;  1KHQ A;  4K7C A;  2ATO A;  1NB5 A;  5J94 A;  3KKU A;  2FUD A;  2G8E A;  3LXS A;  4QRX A;  4XUI A;  2E02 A;  2YJB A;  3KWB X;  5CHV A;  2E01 A;  3H7D A;  3F5V A;  3HD3 A;  1KFU L;  2FTD A;  2E03 A;  4N4Z A;  2IBI A;  4YYV A;  1U9V A;  1CV8 A;  1DEU A;  1PPN A;  2GHU A;  2PAD A;  4QRG A;  3S3Q A;  1AU2 A;  1TLO A;  3V6C A;  3OF9 A;  3QSD A;  3P5X A;  4FK5 A;  1Y4H A;  1VJV A;  3WXE A;  1ATK A;  4YYR A;  3H8B A;  1PPO A;  2AYN A;  2AUZ A;  1EWP A;  2R9C A;  3O0U A;  1ZIV A;  2HXZ A;  1GMY A;  5FPW A;  2P86 A;  2F1G A;  3O1G A;  3V6E A;  2AVW A;  1CTE A;  4BS5 A;  1U9W A;  3P5U A;  2BDZ A;  1QXP A;  1PBH A;  3PNR A;  2AU1 A;  2DC8 A;  4QBB A;  1GCB A;  3D6S A;  3N3G A;  2R9O A;  2HH5 A;  1MS6 A;  3RVX A;  1SP4 B;  1CJL A;  3QT4 A;  2C0Y A;  4X6H A;  3MOR A;  1STF E;  2AYO A;  2DCC A;  3BPF A;  4WA6 A;  3NHE A;  3CH2 X;  1EWM A;  3GCB A;  2PBH A;  3OVZ A;  1YT7 A;  2WBF X;  3MTN A;  4Q8G A;  4P6E A;  3H89 A;  3I3T A;  1EWL A;  1K3B B;  4G54 A;  4CDE B;  1F2B A;  1AU0 A;  2XU4 A;  1X9Y A;  1CB5 A;  4N8W A;  1BQI A;  2B1N A;  2R9N A;  4X6I A;  4CZW A;  4CDF B;  4RY2 A;  3N3K A;  1U9X A;  2CIO A;  4AXM A;  3OIS A;  4W5B A;  1XKG A;  2CB5 A;  4X6J A;  3QJ3 A;  1SNK A;  1QMY A;  2B1M A;  2HHN A;  2NQD B;  2DC7 A;  7PCK A;  1EF7 A;  1HUC B;  4PP2 E;  1FH0 A;  3MHH A;  3CBK A;  3RVW A;  2VHS A;  2FRQ A;  2P7U A;  1ME4 A;  3PDF A;  2YJ8 A;  4P6G A;  3RVV A;  4OEL A;  4FIP A;  2VHF A;  1PXV A;  2OUL A;  2ARY A;  3K24 A;  3KFQ A;  3PBH A;  3IMA A;  1AYV A;  3ERV A;  1AEC A;  4DMX A;  3WXF A;  2FYE A;  1QOL A;  3USV A;  2H7J A;  2NQG A;  1ICF A;  4PI3 A;  3M99 A;  2O6X A;  4OEM A;  2YJ9 A;  2DZY A;  2DCB A;  4N79 A;  5EGW A;  2PNS A;  3KX1 A;  2XU1 A;  1AU3 A;  4CDC B;  3CBJ A;  1PCI A;  4CDD B;  4BQV A;  1ZCM A;  2AS8 A;  2GFO A;  1IWD A;  3I06 A;  1BP4 A;  4YYW A;  4BPV A;  2R6N A;  3S3R A;  1Q6K A;  2DCD A;  1VSN A;  2R9F A;  3WXG A;  1MIR A;  1JQP A;  3K8U A;  2FO5 A;  4DMY A;  1DF0 A;  3MHS A;  2F7D A;  2BDL A;  4XR7 A;  1CPJ A;  1EWO A;  2FQ9 A;  3BC3 A;  6PAD A;  3OF8 A;  4QRV A;  4PAD A;  2R9M A;  4BSQ A;  1KXR A;  3U8E A;  4YYU A;  1O0E A;  2NQI A;  4W5C A;  4I04 A;  1MHW A;  1KHP A;  3IEJ A;  2YJC A;  3P5V A;  4I07 A;  2DC6 A;  1PPP A;  1AYW A;  3HWN A;  4I05 A;  2OP3 A;  1POP A;  4HWY A;  3AI8 A;  5A24 A;  1YK8 A;  2G6D A;  1BY8 A;  3E1Z B;  1NL6 A; 
#chains in the Genus database with same CATH topology
 1U5I A;  3PT2 A;  3TMP A;  3BPM A;  3RNV A;  1YAL A;  5JA7 A;  1MDW A;  2OZ2 A;  3DF0 A;  3TNX A;  3IHP A;  1CSB B;  1PPD A;  2XU3 A;  3ZUA A;  2XU5 A;  3CH3 X;  1GEC E;  2G7Y A;  4M0W A;  1ME3 A;  3PRM A;  4PT5 A;  4QH6 A;  2UZJ A;  4BOS A;  1QDQ A;  4D8I A;  2YJ2 A;  1NQC A;  4YV8 A;  1TU6 A;  3OVX A;  5JH3 A;  2FRA A;  2E00 A;  4MSX A;  2P0R A;  3PW3 A;  5K16 A;  1TL9 A;  4RF1 A;  5CVO B;  3BWK A;  4D8E A;  1MEM A;  4RKX A;  3MTV A;  4W4U A;  3IUT A;  1S4V A;  2NQA A;  3W30 A;  3H6S A;  4YYS A;  5CVM A;  3C9E A;  2IPP B;  3IV2 A;  4PP1 A;  3K9M A;  1A6R A;  4MZO A;  3IOQ A;  5CHT A;  3PSE A;  1BGO A;  2PRE A;  4KLB A;  4FJC A;  5PAD A;  1NPZ A;  4MZS A;  5EZQ A;  3KW9 A;  2Y6E A;  2Y5B A;  1MEG A;  1U9Q X;  5EF4 A;  3PRP A;  1AU4 A;  2DCA A;  3N4C A;  3BCN A;  1F29 A;  1Y08 A;  4IP3 A;  4YYQ A;  2AIM A;  1NLJ A;  1NB3 A;  1PVJ A;  2DJG B;  4BS6 A;  1F2A A;  3BOW A;  4Q8H A;  3LFY A;  4OVZ A;  3H8C A;  2DJF B;  2ACT A;  2HD5 A;  3B79 A;  3KSE A;  2DZZ A;  1THE A;  1AIM A;  1GLO A;  4AXL A;  1CQD A;  3PHU A;  1CVZ A;  5F02 A;  4BOQ A;  2FT2 A;  3HHA A;  3KWZ A;  1PAD A;  1KFX L;  4WUR A;  4YVA A;  1AYU A;  1PE6 A;  5JZE A;  8PCH A;  2AUX A;  4ZUX U;  1CS8 A;  1UKF A;  1YK7 A;  2JQF R;  9PAP A;  3P5W A;  1M6D A;  3F75 A;  3HHI A;  1YVB A;  3E9S A;  2G8J A;  1F2C A;  1PIP A;  2DC9 A;  2JQG R;  2BTW B;  5CVN B;  1ITO A;  1KHQ A;  4HXD B;  4K7C A;  2ATO A;  1NB5 A;  3B21 A;  5J94 A;  3KKU A;  2FUD A;  2G8E A;  5E6J A;  3LXS A;  4QRX A;  4XUI A;  2E02 A;  2YJB A;  3KWB X;  5CHV A;  2E01 A;  3H7D A;  3F5V A;  4IUM A;  3BB7 A;  3HD3 A;  1KFU L;  2FTD A;  4MM3 B;  2E03 A;  4N4Z A;  2IBI A;  4YYV A;  1U9V A;  1CV8 A;  1DEU A;  1PPN A;  2GHU A;  2PAD A;  4QRG A;  3S3Q A;  1AU2 A;  1TLO A;  3V6C A;  3OF9 A;  3QSD A;  3P5X A;  4FK5 A;  1Y4H A;  4RF0 A;  1VJV A;  5EZS A;  3BBA A;  3WXE A;  1ATK A;  4YYR A;  3H8B A;  1PPO A;  2AYN A;  2AUZ A;  3BY4 A;  1EWP A;  2R9C A;  3O0U A;  1ZIV A;  4GUA A;  2HXZ A;  1GMY A;  5FPW A;  2P86 A;  2F1G A;  4MI7 A;  3O1G A;  5KO3 A;  3V6E A;  2AVW A;  1CTE A;  4BS5 A;  1U9W A;  3P5U A;  2BDZ A;  1QXP A;  2BU3 A;  3IFU A;  4REZ A;  4BOZ A;  1PBH A;  3PNR A;  2AU1 A;  2DC8 A;  4QBB A;  1GCB A;  3D6S A;  3N3G A;  2R9O A;  2HH5 A;  1MS6 A;  3RVX A;  1SP4 B;  1CJL A;  3QT4 A;  2C0Y A;  4X6H A;  2FE8 A;  3MOR A;  1STF E;  2AYO A;  2DCC A;  3BPF A;  4WA6 A;  3NHE A;  3CH2 X;  1EWM A;  3GCB A;  2PBH A;  3OVZ A;  1YT7 A;  2WBF X;  3MTN A;  4RNA A;  4Q8G A;  4P6E A;  3H89 A;  3I3T A;  1EWL A;  1K3B B;  4G54 A;  4CDE B;  1F2B A;  1AU0 A;  2XU4 A;  1X9Y A;  1CB5 A;  4N8W A;  1BQI A;  2B1N A;  2R9N A;  4X6I A;  4CZW A;  2DOS A;  4CDF B;  4RY2 A;  3N3K A;  1U9X A;  2CIO A;  4AXM A;  4A5U A;  3OIS A;  4W5B A;  1XKG A;  4BOU A;  2CB5 A;  4X6J A;  3QJ3 A;  1SNK A;  1QMY A;  2B1M A;  2HHN A;  2NQD B;  3PHW A;  2DC7 A;  7PCK A;  1EF7 A;  1HUC B;  3ZNH A;  4PP2 E;  3MP2 A;  1FH0 A;  3MHH A;  3CBK A;  3RVW A;  2VHS A;  2FRQ A;  2P7U A;  1ME4 A;  3PDF A;  2YJ8 A;  4P6G A;  3RVV A;  2JTC A;  4OEL A;  2BTW A;  3W31 A;  4FIP A;  2VHF A;  1PXV A;  2OUL A;  2ARY A;  3K24 A;  4ZTB A;  2J7Q C;  3KFQ A;  3PBH A;  3IMA A;  1AYV A;  2Z84 A;  3ERV A;  1AEC A;  4DMX A;  3WXF A;  2FYE A;  1QOL A;  3USV A;  2H7J A;  2NQG A;  1ICF A;  4D8B A;  4PI3 A;  3M99 A;  2O6X A;  4OEM A;  2YJ9 A;  2DZY A;  2DCB A;  4N79 A;  5EGW A;  2PNS A;  3KX1 A;  2XU1 A;  1AU3 A;  4CDC B;  3CBJ A;  1PCI A;  4OVZ B;  4CDD B;  4BQV A;  1ZCM A;  3C0R A;  2AS8 A;  2GFO A;  3PHX A;  1IWD A;  3I06 A;  4BOP A;  1BP4 A;  4YYW A;  4XZX A;  4BPV A;  2R6N A;  3S3R A;  1Q6K A;  2DCD A;  1VSN A;  2R9F A;  1YZB A;  3WXG A;  1MIR A;  1JQP A;  2AGA A;  2HWK A;  3K8U A;  2FO5 A;  4DMY A;  1DF0 A;  3MHS A;  2F7D A;  2BDL A;  4XR7 A;  1CPJ A;  1EWO A;  2FQ9 A;  3BC3 A;  6PAD A;  3OF8 A;  4QRV A;  4PAD A;  4P16 A;  2R9M A;  4BSQ A;  1KXR A;  3U8E A;  4YYU A;  1O0E A;  2JRI A;  2NQI A;  3O65 A;  3TRK A;  4W5C A;  4I04 A;  1MHW A;  1KHP A;  4R3D A;  3IEJ A;  3OQC A;  2YJC A;  3P5V A;  4I07 A;  3MJ5 A;  2DC6 A;  1PPP A;  1AYW A;  3HWN A;  4I05 A;  2OP3 A;  1POP A;  4OW0 A;  4HWY A;  3AI8 A;  5A24 A;  1YK8 A;  2G6D A;  1DKI A;  1BY8 A;  3E1Z B;  1NL6 A;  2J7Q A; 
#chains in the Genus database with same CATH homology
 1U5I A;  4B55 A;  3BPM A;  1YAL A;  5JA7 A;  1MDW A;  2OZ2 A;  3DF0 A;  3TNX A;  3IHP A;  4NV7 A;  1CSB B;  1PPD A;  2XU3 A;  3ZUA A;  2XU5 A;  3CH3 X;  1GEC E;  2G7Y A;  1ME3 A;  4BGF A;  4QH6 A;  1QDQ A;  2YJ2 A;  1NQC A;  4YV8 A;  1TU6 A;  3OVX A;  4GUZ A;  5JH3 A;  2FRA A;  2E00 A;  4MSX A;  2P0R A;  3PW3 A;  5K16 A;  1TL9 A;  5CVO B;  3BWK A;  1MEM A;  4W4U A;  2VFB A;  3IUT A;  1S4V A;  2NQA A;  3H6S A;  4YYS A;  5CVM A;  3C9E A;  2IPP B;  3IV2 A;  4PP1 A;  3K9M A;  1A6R A;  4MZO A;  3IOQ A;  4NV8 A;  5CHT A;  1BGO A;  2PRE A;  4KLB A;  4FJC A;  5PAD A;  1NPZ A;  4MZS A;  3KW9 A;  2Y6E A;  2Y5B A;  1W5R A;  1MEG A;  1U9Q X;  5EF4 A;  1AU4 A;  2DCA A;  3N4C A;  3BCN A;  1F29 A;  1Y08 A;  4YYQ A;  2AIM A;  1NLJ A;  1NB3 A;  2DJG B;  4BS6 A;  1F2A A;  3BOW A;  4Q8H A;  3LFY A;  3H8C A;  2DJF B;  2ACT A;  2HD5 A;  3B79 A;  3KSE A;  2DZZ A;  1THE A;  1AIM A;  1GLO A;  4AXL A;  1CQD A;  1CVZ A;  5F02 A;  2FT2 A;  3HHA A;  3KWZ A;  1PAD A;  1KFX L;  4YVA A;  1AYU A;  1PE6 A;  4C5P A;  8PCH A;  2AUX A;  4ZUX U;  1CS8 A;  1YK7 A;  2JQF R;  9PAP A;  3P5W A;  1M6D A;  3F75 A;  3HHI A;  1YVB A;  2G8J A;  1F2C A;  1PIP A;  2DC9 A;  2JQG R;  5CVN B;  1ITO A;  1KHQ A;  4K7C A;  2ATO A;  1NB5 A;  5J94 A;  3KKU A;  2FUD A;  2G8E A;  3LXS A;  4QRX A;  4XUI A;  2E02 A;  2YJB A;  3KWB X;  5CHV A;  2E01 A;  3H7D A;  3F5V A;  3HD3 A;  1KFU L;  2FTD A;  2E03 A;  4N4Z A;  2IBI A;  4YYV A;  1U9V A;  1CV8 A;  1DEU A;  1PPN A;  2GHU A;  2PAD A;  4QRG A;  3S3Q A;  1AU2 A;  1TLO A;  3V6C A;  3OF9 A;  3QSD A;  3P5X A;  4FK5 A;  1Y4H A;  1VJV A;  3WXE A;  1ATK A;  4YYR A;  3H8B A;  1PPO A;  2AYN A;  2AUZ A;  1EWP A;  2R9C A;  3O0U A;  1ZIV A;  2HXZ A;  1GMY A;  5FPW A;  2P86 A;  2F1G A;  3O1G A;  3V6E A;  2AVW A;  1CTE A;  4BS5 A;  1U9W A;  3P5U A;  2BDZ A;  1QXP A;  1PBH A;  3PNR A;  2AU1 A;  2DC8 A;  4QBB A;  1GCB A;  3D6S A;  3N3G A;  2R9O A;  2HH5 A;  1MS6 A;  3RVX A;  1SP4 B;  1CJL A;  3QT4 A;  2C0Y A;  4X6H A;  3MOR A;  1STF E;  2AYO A;  2DCC A;  3BPF A;  4WA6 A;  3NHE A;  3CH2 X;  1EWM A;  3GCB A;  2PBH A;  3OVZ A;  1YT7 A;  2WBF X;  3MTN A;  4Q8G A;  4P6E A;  3H89 A;  3I3T A;  1EWL A;  1K3B B;  4G54 A;  4CDE B;  1F2B A;  1AU0 A;  1W6F A;  2XU4 A;  1X9Y A;  1CB5 A;  4N8W A;  1BQI A;  2B1N A;  2R9N A;  4X6I A;  4CZW A;  4CDF B;  4RY2 A;  1E2T A;  3N3K A;  1U9X A;  2CIO A;  4AXM A;  3OIS A;  4W5B A;  1XKG A;  2CB5 A;  4X6J A;  3QJ3 A;  1SNK A;  1QMY A;  2B1M A;  2HHN A;  2NQD B;  2DC7 A;  7PCK A;  1EF7 A;  1HUC B;  4PP2 E;  1FH0 A;  3MHH A;  3CBK A;  3RVW A;  2VHS A;  2FRQ A;  2P7U A;  1ME4 A;  3PDF A;  2YJ8 A;  4P6G A;  3RVV A;  4OEL A;  4FIP A;  2VHF A;  1PXV A;  2OUL A;  2ARY A;  3K24 A;  3KFQ A;  3PBH A;  3IMA A;  1AYV A;  1W4T A;  3ERV A;  1AEC A;  4DMX A;  3WXF A;  2FYE A;  1QOL A;  3USV A;  2H7J A;  2NQG A;  1ICF A;  4PI3 A;  3M99 A;  2O6X A;  4OEM A;  2YJ9 A;  2DZY A;  2DCB A;  4N79 A;  5EGW A;  2PNS A;  3KX1 A;  2XU1 A;  1AU3 A;  2VFC A;  2BSZ A;  4CDC B;  3CBJ A;  1PCI A;  4CDD B;  4BQV A;  1ZCM A;  2AS8 A;  2GFO A;  1IWD A;  3I06 A;  1BP4 A;  4YYW A;  4BPV A;  2R6N A;  3S3R A;  1Q6K A;  2DCD A;  1VSN A;  2R9F A;  3WXG A;  1MIR A;  1JQP A;  3K8U A;  2FO5 A;  4DMY A;  1DF0 A;  3MHS A;  2F7D A;  2BDL A;  4XR7 A;  1CPJ A;  1EWO A;  2FQ9 A;  3BC3 A;  6PAD A;  3OF8 A;  4QRV A;  4PAD A;  2R9M A;  4BSQ A;  1KXR A;  3U8E A;  1GX3 A;  4YYU A;  1O0E A;  3LTW A;  2NQI A;  4W5C A;  4I04 A;  1MHW A;  1KHP A;  3D9W A;  3IEJ A;  2YJC A;  3P5V A;  4I07 A;  2DC6 A;  1PPP A;  1AYW A;  3HWN A;  4I05 A;  2OP3 A;  1POP A;  4HWY A;  3AI8 A;  5A24 A;  1YK8 A;  2G6D A;  1BY8 A;  3E1Z B;  1NL6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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