1U9WA

Crystal structure of the cysteine protease human cathepsin k in complex with the covalent inhibitor nvp-abi491
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
216
structure length
216
Chain Sequence
RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
pubmed doi rcsb
molecule keywords Cathepsin K
total genus 61
structure length 216
sequence length 216
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2004-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1u9wA00
1BY8A 2R9MA 3E1ZB 4CDFB 4AXMA 3H89A 2FRAA 3CBJA 3KW9A 1THEA 1AYWA 2JQGR 1EF7A 3P5XA 2FYEA 3O0UA 2AYOA 2P0RA 1AIMA 3RVXA 5PADA 3S3QA 4CDDB 2BDZA 1GMYA 1ICFA 2IBIA 3IEJA 5F02A 3U8EA 4P6GA 1NQCA 4FJCA 3ZUAA 3BC3A 3CBKA 2C0YA 3S3RA 2G6DA 3N4CA 1Y08A 1O0EA 4MSXA 1F2BA 3CH3X 3I3TA 1F2AA 1YALA 2AUZA 1Y4HA 3KFQA 3MTNA 3MHHA 2XU5A 2FRQA 1NB3A 4OELA 2Y5BA 2E01A 2H7JA 5EGWA 4FIPA 1PBHA 3HD3A 4CDEB 1MEGA 4N4ZA 2G7YA 1STFE 1S4VA 3V6CA 2GFOA 4BS6A 3MHSA 2E03A 3ERVA 3HWNA 4W4UA 1GECE 1HUCB 2DCDA 3PDFA 4BSQA 1YT7A 2ACTA 5A24A 8PCHA 3N3GA 1PE6A 1U9XA 2DCCA 4YYWA 4YYVA 3OISA 3WXGA 1KHPA 2NQGA 2R6NA 4BQVA 3HHAA 1U5IA 1IWDA 1ZIVA 4KLBA 4X6HA 4DMXA 2FTDA 4G54A 4RY2A 4QBBA 3NHEA 1YK7A 2NQIA 4QRXA 3C9EA 2DZYA 4W5BA 3KWBX 4BS5A 2DCAA 1KFXL 2P7UA 3LFYA 4W5CA 1Q6KA 2FO5A 3PNRA 3F5VA 2OZ2A 3AI8A 2E02A 3V6EA 2FQ9A 1A6RA 3CH2X 4PP1A 2IPPB 2CB5A 4PADA 2FUDA 4QRGA 2YJCA 3RVVA 1AYVA 1BQIA 5CHTA 4CZWA 3OF9A 2DJGB 1KHQA 3OVZA 4K7CA 1CJLA 3H7DA 4DMYA 1QXPA 3MORA 4FK5A 1ZCMA 1MDWA 1GCBA 4XUIA 2G8EA 2R9CA 3KKUA 2DC9A 2P86A 1X9YA 2VHFA 1CB5A 1CPJA 1K3BB 1AU2A 2B1MA 3IV2A 3KX1A 1QDQA 7PCKA 1DF0A 2FT2A 2BDLA 1AU0A 4YYSA 3K24A 3TNXA 1VJVA 2PREA 1U9VA 3P5WA 3F75A 4X6JA 3IOQA 1QMYA 3RVWA 3USVA 4QRVA 1DEUA 1CVZA 5JH3A 2AIMA 3BPFA 1F2CA 1EWMA 1AYUA 3IHPA 2AVWA 1PPNA 1AU4A 2DC6A 2AUXA 1EWOA 4X6IA 1PPPA 3B79A 1TLOA 2B1NA 1EWPA 1FH0A 2GHUA 5EF4A 1MHWA 2ATOA 2WBFX 3BWKA 3HHIA 1YK8A 2CIOA 2XU1A 2NQDB 5JA7A 2NQAA 2XU3A 1QOLA 2AU1A 4N79A 3QJ3A 4YYQA 3KSEA 1ME3A 2YJ2A 1MEMA 2PBHA 4YYRA 2F1GA 3QSDA 3GCBA 4MZOA 4OEMA 3K8UA 2YJBA 2AS8A 2YJ8A 1JQPA 1VSNA 1GLOA 4QH6A 3WXEA 3D6SA 4XR7A 1M6DA 1KXRA 3QT4A 1NB5A 3BOWA 3BCNA 2AYNA 1XKGA 2DC7A 1PPDA 4MZSA 3DF0A 3WXFA 1NL6A 2VHSA 1MIRA 1ME4A 2HH5A 1SNKA 1ATKA 1AU3A 3IUTA 5CVNB 2YJ9A 1BGOA 2DC8A 2JQFR 3M99A 4HWYA 1PPOA 1CQDA 1PXVA 3H8CA 4ZUXU 3K9MA 1TL9A 3OVXA 2HHNA 2HD5A 4I07A 1ITOA 2PNSA 2R9OA 1SP4B 3N3KA 4AXLA 1KFUL 3LXSA 4CDCB 2DCBA 1PCIA 2ARYA 4I05A 3P5VA 1CSBB 1NLJA 4PI3A 2R9NA 1NPZA 3OF8A 2PADA 1CTEA 4BPVA 2G8JA 3IMAA 1BP4A 5CVMA 4PP2E 1F29A 9PAPA 2OP3A 3PW3A 4Q8HA 2R9FA 5J94A 1POPA 1EWLA 4YYUA 3I06A 1PIPA 1CV8A 5CVOB 6PADA 3H6SA 1MS6A 2OULA 2XU4A 1AECA 4Q8GA 1YVBA 2O6XA 4WA6A 1TU6A 1U9QX 1U9WA 3O1GA 3KWZA 2E00A 2Y6EA 5FPWA 4YVAA 1CS8A 3BPMA 4I04A 3PBHA 3P5UA 2DZZA 4P6EA 1PADA 4N8WA 5CHVA 5K16A 3H8BA 2F7DA 2DJFB 4YV8A 2HXZA
chains in the Genus database with same CATH superfamily
1BY8A 2R9MA 3E1ZB 4CDFB 4AXMA 3H89A 2FRAA 3CBJA 3KW9A 1THEA 1AYWA 2JQGR 1EF7A 1PVJA 3P5XA 2FYEA 3O0UA 4BOSA 2AYOA 2P0RA 1AIMA 3RVXA 5PADA 3S3QA 4CDDB 2BDZA 1GMYA 1ICFA 3PHXA 2IBIA 3IEJA 4RF1A 5F02A 3U8EA 4P6GA 1NQCA 4FJCA 4BOUA 3ZUAA 3BC3A 3CBKA 2C0YA 3S3RA 2G6DA 3N4CA 3B21A 1Y08A 1O0EA 4MSXA 1F2BA 3CH3X 3I3TA 4GUAA 1F2AA 1YALA 2AUZA 1Y4HA 3KFQA 3IFUA 3MTNA 3MHHA 2XU5A 2FRQA 1NB3A 2JRIA 4OELA 2Y5BA 4IUMA 2E01A 2H7JA 5EGWA 4FIPA 1PBHA 3W31A 5EZQA 3HD3A 4CDEB 1MEGA 4N4ZA 2G7YA 1STFE 2FE8A 1S4VA 3V6CA 2GFOA 4BS6A 3MHSA 2E03A 3ERVA 3MTVA 3HWNA 3PRPA 4W4UA 1GECE 5E6JA 1HUCB 2DCDA 1YZBA 3PDFA 4BSQA 1YT7A 2ACTA 5A24A 8PCHA 3N3GA 4PT5A 1PE6A 1U9XA 4OVZA 2DCCA 4YYWA 4YYVA 3OISA 3WXGA 4HXDB 1KHPA 2NQGA 2BU3A 2R6NA 4BQVA 3HHAA 1U5IA 4A5UA 1IWDA 1ZIVA 4KLBA 4X6HA 4DMXA 2FTDA 3PSEA 4G54A 4RY2A 4QBBA 3NHEA 1YK7A 3PHUA 2NQIA 4QRXA 3C9EA 4BOPA 2DZYA 4W5BA 3KWBX 4BS5A 4IP3A 2DCAA 1KFXL 2P7UA 3LFYA 4W5CA 1Q6KA 2FO5A 3PNRA 3C0RA 4R3DA 3F5VA 2OZ2A 3AI8A 2E02A 3V6EA 2FQ9A 1A6RA 3BBAA 3CH2X 4PP1A 2IPPB 2CB5A 4PADA 2FUDA 4QRGA 2YJCA 3PHWA 3TMPA 3RVVA 1AYVA 1BQIA 5CHTA 4CZWA 3OF9A 2DJGB 1KHQA 3OVZA 4K7CA 4RF0A 4RKXA 3ZNHA 1CJLA 3H7DA 4DMYA 1QXPA 3MORA 4FK5A 1ZCMA 3PRMA 1MDWA 1GCBA 4XUIA 2G8EA 2R9CA 3KKUA 2DC9A 2P86A 1X9YA 4MI7A 2VHFA 1CB5A 1CPJA 1K3BB 1AU2A 2B1MA 3IV2A 3KX1A 2J7QC 1QDQA 7PCKA 1DF0A 2J7QA 2FT2A 2BDLA 1AU0A 4YYSA 2UZJA 3K24A 3TNXA 1VJVA 1DKIA 1U9VA 2PREA 3P5WA 3F75A 4X6JA 3PT2A 2BTWA 3IOQA 1QMYA 3RVWA 3USVA 4QRVA 1DEUA 1CVZA 5JH3A 2AIMA 3BPFA 1F2CA 1EWMA 1AYUA 3IHPA 2AVWA 1PPNA 1AU4A 2DC6A 2AUXA 1EWOA 4X6IA 1PPPA 3B79A 1TLOA 2B1NA 1EWPA 5EZSA 1FH0A 2GHUA 5EF4A 1MHWA 2ATOA 2WBFX 3BWKA 3HHIA 4XZXA 1YK8A 2CIOA 2XU1A 2NQDB 5JA7A 2NQAA 2XU3A 1QOLA 2AU1A 4N79A 3QJ3A 4YYQA 2Z84A 3KSEA 1ME3A 2YJ2A 1MEMA 2PBHA 4YYRA 2F1GA 4BOQA 3E9SA 3QSDA 3GCBA 4MZOA 4OEMA 2AGAA 3TRKA 3K8UA 2YJBA 2AS8A 2YJ8A 1JQPA 1VSNA 1GLOA 4QH6A 4RNAA 3WXEA 3D6SA 4XR7A 1M6DA 1KXRA 3QT4A 1NB5A 4P16A 3BOWA 3BCNA 2AYNA 1XKGA 4ZTBA 2DC7A 1PPDA 4MZSA 3DF0A 3WXFA 1NL6A 2VHSA 1MIRA 1ME4A 2HH5A 3BB7A 1SNKA 4OVZB 1ATKA 1AU3A 3IUTA 4OW0A 4BOZA 5CVNB 4D8EA 2YJ9A 1BGOA 2DC8A 2JQFR 3M99A 4HWYA 1PPOA 1CQDA 1PXVA 4D8IA 3H8CA 4ZUXU 3K9MA 4WURA 1TL9A 3OVXA 5JZEA 2HHNA 2HD5A 4I07A 1ITOA 2PNSA 2HWKA 2R9OA 1SP4B 3N3KA 4AXLA 1KFUL 3LXSA 4CDCB 2DCBA 1PCIA 2ARYA 4I05A 3P5VA 1CSBB 1NLJA 2JTCA 4PI3A 2R9NA 1NPZA 3OF8A 2PADA 1CTEA 4BPVA 2G8JA 1UKFA 3MP2A 3IMAA 1BP4A 5CVMA 4PP2E 1F29A 3BY4A 5KO3A 9PAPA 2OP3A 3PW3A 4MM3B 4Q8HA 3OQCA 2R9FA 4REZA 2DOSA 5J94A 1POPA 1EWLA 4YYUA 3I06A 1PIPA 1CV8A 5CVOB 6PADA 3W30A 3H6SA 1MS6A 2OULA 2XU4A 1AECA 4Q8GA 1YVBA 2O6XA 4WA6A 1TU6A 1U9QX 1U9WA 3O1GA 3KWZA 2E00A 2Y6EA 3MJ5A 4D8BA 5FPWA 3O65A 1CS8A 3BPMA 4YVAA 3RNVA 4I04A 3PBHA 3P5UA 2DZZA 4P6EA 1PADA 4N8WA 5CHVA 4M0WA 5K16A 2BTWB 3H8BA 2F7DA 2DJFB 4YV8A 2HXZA
chains in the Genus database with same CATH topology
1BY8A 2R9MA 3E1ZB 4CDFB 4AXMA 3H89A 2FRAA 3CBJA 3KW9A 1THEA 1AYWA 2JQGR 1EF7A 3P5XA 2FYEA 3O0UA 2AYOA 2P0RA 1AIMA 3RVXA 5PADA 3S3QA 4CDDB 2BDZA 1GMYA 1ICFA 2IBIA 3IEJA 1E2TA 5F02A 3U8EA 4P6GA 1NQCA 4FJCA 3ZUAA 3BC3A 3CBKA 2C0YA 3S3RA 2G6DA 3N4CA 1Y08A 1O0EA 4MSXA 1F2BA 3CH3X 3I3TA 1F2AA 1YALA 2AUZA 1W5RA 1Y4HA 3KFQA 3MTNA 3MHHA 2XU5A 2FRQA 1NB3A 4OELA 2Y5BA 4NV8A 2E01A 2H7JA 5EGWA 4FIPA 1PBHA 3HD3A 4CDEB 1MEGA 4N4ZA 2G7YA 1STFE 1S4VA 3V6CA 2GFOA 4BS6A 3MHSA 2E03A 3ERVA 3HWNA 4W4UA 1GECE 2VFCA 1HUCB 4C5PA 2DCDA 1GX3A 3PDFA 4BSQA 1YT7A 2ACTA 5A24A 8PCHA 3N3GA 1PE6A 1U9XA 2DCCA 4YYWA 4YYVA 3OISA 3WXGA 1KHPA 2NQGA 2R6NA 4BQVA 3HHAA 1U5IA 1IWDA 1ZIVA 4KLBA 4X6HA 4NV7A 4DMXA 4B55A 2FTDA 4G54A 4RY2A 4QBBA 3NHEA 1YK7A 2NQIA 4QRXA 3C9EA 2DZYA 4W5BA 3KWBX 4BS5A 4GUZA 2DCAA 1KFXL 2P7UA 3LFYA 4W5CA 1Q6KA 2FO5A 3PNRA 3F5VA 2OZ2A 3AI8A 2E02A 3V6EA 2FQ9A 1A6RA 3CH2X 4PP1A 2IPPB 2CB5A 4PADA 2FUDA 4QRGA 2YJCA 3RVVA 1AYVA 1BQIA 5CHTA 4CZWA 3OF9A 1W4TA 2DJGB 1KHQA 3OVZA 4K7CA 1CJLA 3H7DA 4DMYA 1QXPA 3MORA 4FK5A 1ZCMA 1MDWA 1GCBA 4XUIA 2G8EA 2R9CA 3KKUA 2DC9A 2P86A 1X9YA 2VHFA 1CB5A 1CPJA 1K3BB 1AU2A 2B1MA 3IV2A 3KX1A 1QDQA 7PCKA 1DF0A 2FT2A 2BDLA 1AU0A 4YYSA 3K24A 3TNXA 1VJVA 2PREA 1U9VA 1W6FA 3P5WA 3F75A 4X6JA 3IOQA 1QMYA 3RVWA 3USVA 4QRVA 1DEUA 1CVZA 5JH3A 2AIMA 3BPFA 1F2CA 1EWMA 1AYUA 3IHPA 2AVWA 1PPNA 1AU4A 2DC6A 2AUXA 1EWOA 4X6IA 1PPPA 3B79A 1TLOA 2B1NA 1EWPA 1FH0A 2GHUA 5EF4A 1MHWA 2ATOA 2WBFX 3BWKA 3HHIA 1YK8A 2CIOA 2XU1A 2NQDB 5JA7A 2NQAA 2XU3A 1QOLA 2AU1A 4N79A 3QJ3A 4YYQA 3KSEA 1ME3A 2YJ2A 1MEMA 2PBHA 4YYRA 2F1GA 3QSDA 3GCBA 4MZOA 4OEMA 3K8UA 2YJBA 2AS8A 2YJ8A 1JQPA 1VSNA 1GLOA 4QH6A 3WXEA 3D6SA 4XR7A 1M6DA 1KXRA 3QT4A 1NB5A 3BOWA 3BCNA 2AYNA 1XKGA 2DC7A 1PPDA 4MZSA 3DF0A 3WXFA 1NL6A 2VHSA 1MIRA 1ME4A 2HH5A 1SNKA 1ATKA 1AU3A 3IUTA 5CVNB 2YJ9A 1BGOA 2DC8A 2JQFR 3M99A 4HWYA 1PPOA 1CQDA 1PXVA 3H8CA 4ZUXU 3K9MA 1TL9A 3OVXA 2HHNA 2HD5A 4I07A 1ITOA 2PNSA 2R9OA 1SP4B 3N3KA 4AXLA 1KFUL 3LXSA 4CDCB 2DCBA 1PCIA 2ARYA 4I05A 3P5VA 1CSBB 1NLJA 4PI3A 2R9NA 1NPZA 3OF8A 2PADA 1CTEA 4BPVA 2G8JA 3IMAA 1BP4A 5CVMA 4PP2E 1F29A 2BSZA 9PAPA 2OP3A 3PW3A 4Q8HA 2R9FA 5J94A 1POPA 1EWLA 4YYUA 3I06A 1PIPA 1CV8A 3LTWA 5CVOB 6PADA 3H6SA 1MS6A 2OULA 2XU4A 1AECA 4Q8GA 1YVBA 2O6XA 4WA6A 1TU6A 1U9QX 1U9WA 4BGFA 3O1GA 3KWZA 2E00A 2Y6EA 5FPWA 4YVAA 1CS8A 3BPMA 4I04A 2VFBA 3PBHA 3P5UA 2DZZA 4P6EA 1PADA 4N8WA 5CHVA 5K16A 3H8BA 2F7DA 3D9WA 2DJFB 4YV8A 2HXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BY8 A;  2R9M A;  3E1Z B;  4CDF B;  4AXM A;  3H89 A;  2FRA A;  3CBJ A;  3KW9 A;  1THE A;  1AYW A;  2JQG R;  1EF7 A;  3P5X A;  2FYE A;  3O0U A;  2AYO A;  2P0R A;  1AIM A;  3RVX A;  5PAD A;  3S3Q A;  4CDD B;  2BDZ A;  1GMY A;  1ICF A;  2IBI A;  3IEJ A;  5F02 A;  3U8E A;  4P6G A;  1NQC A;  4FJC A;  3ZUA A;  3BC3 A;  3CBK A;  2C0Y A;  3S3R A;  2G6D A;  3N4C A;  1Y08 A;  1O0E A;  4MSX A;  1F2B A;  3CH3 X;  3I3T A;  1F2A A;  1YAL A;  2AUZ A;  1Y4H A;  3KFQ A;  3MTN A;  3MHH A;  2XU5 A;  2FRQ A;  1NB3 A;  4OEL A;  2Y5B A;  2E01 A;  2H7J A;  5EGW A;  4FIP A;  1PBH A;  3HD3 A;  4CDE B;  1MEG A;  4N4Z A;  2G7Y A;  1STF E;  1S4V A;  3V6C A;  2GFO A;  4BS6 A;  3MHS A;  2E03 A;  3ERV A;  3HWN A;  4W4U A;  1GEC E;  1HUC B;  2DCD A;  3PDF A;  4BSQ A;  1YT7 A;  2ACT A;  5A24 A;  8PCH A;  3N3G A;  1PE6 A;  1U9X A;  2DCC A;  4YYW A;  4YYV A;  3OIS A;  3WXG A;  1KHP A;  2NQG A;  2R6N A;  4BQV A;  3HHA A;  1U5I A;  1IWD A;  1ZIV A;  4KLB A;  4X6H A;  4DMX A;  2FTD A;  4G54 A;  4RY2 A;  4QBB A;  3NHE A;  1YK7 A;  2NQI A;  4QRX A;  3C9E A;  2DZY A;  4W5B A;  3KWB X;  4BS5 A;  2DCA A;  1KFX L;  2P7U A;  3LFY A;  4W5C A;  1Q6K A;  2FO5 A;  3PNR A;  3F5V A;  2OZ2 A;  3AI8 A;  2E02 A;  3V6E A;  2FQ9 A;  1A6R A;  3CH2 X;  4PP1 A;  2IPP B;  2CB5 A;  4PAD A;  2FUD A;  4QRG A;  2YJC A;  3RVV A;  1AYV A;  1BQI A;  5CHT A;  4CZW A;  3OF9 A;  2DJG B;  1KHQ A;  3OVZ A;  4K7C A;  1CJL A;  3H7D A;  4DMY A;  1QXP A;  3MOR A;  4FK5 A;  1ZCM A;  1MDW A;  1GCB A;  4XUI A;  2G8E A;  2R9C A;  3KKU A;  2DC9 A;  2P86 A;  1X9Y A;  2VHF A;  1CB5 A;  1CPJ A;  1K3B B;  1AU2 A;  2B1M A;  3IV2 A;  3KX1 A;  1QDQ A;  7PCK A;  1DF0 A;  2FT2 A;  2BDL A;  1AU0 A;  4YYS A;  3K24 A;  3TNX A;  1VJV A;  2PRE A;  1U9V A;  3P5W A;  3F75 A;  4X6J A;  3IOQ A;  1QMY A;  3RVW A;  3USV A;  4QRV A;  1DEU A;  1CVZ A;  5JH3 A;  2AIM A;  3BPF A;  1F2C A;  1EWM A;  1AYU A;  3IHP A;  2AVW A;  1PPN A;  1AU4 A;  2DC6 A;  2AUX A;  1EWO A;  4X6I A;  1PPP A;  3B79 A;  1TLO A;  2B1N A;  1EWP A;  1FH0 A;  2GHU A;  5EF4 A;  1MHW A;  2ATO A;  2WBF X;  3BWK A;  3HHI A;  1YK8 A;  2CIO A;  2XU1 A;  2NQD B;  5JA7 A;  2NQA A;  2XU3 A;  1QOL A;  2AU1 A;  4N79 A;  3QJ3 A;  4YYQ A;  3KSE A;  1ME3 A;  2YJ2 A;  1MEM A;  2PBH A;  4YYR A;  2F1G A;  3QSD A;  3GCB A;  4MZO A;  4OEM A;  3K8U A;  2YJB A;  2AS8 A;  2YJ8 A;  1JQP A;  1VSN A;  1GLO A;  4QH6 A;  3WXE A;  3D6S A;  4XR7 A;  1M6D A;  1KXR A;  3QT4 A;  1NB5 A;  3BOW A;  3BCN A;  2AYN A;  1XKG A;  2DC7 A;  1PPD A;  4MZS A;  3DF0 A;  3WXF A;  1NL6 A;  2VHS A;  1MIR A;  1ME4 A;  2HH5 A;  1SNK A;  1ATK A;  1AU3 A;  3IUT A;  5CVN B;  2YJ9 A;  1BGO A;  2DC8 A;  2JQF R;  3M99 A;  4HWY A;  1PPO A;  1CQD A;  1PXV A;  3H8C A;  4ZUX U;  3K9M A;  1TL9 A;  3OVX A;  2HHN A;  2HD5 A;  4I07 A;  1ITO A;  2PNS A;  2R9O A;  1SP4 B;  3N3K A;  4AXL A;  1KFU L;  3LXS A;  4CDC B;  2DCB A;  1PCI A;  2ARY A;  4I05 A;  3P5V A;  1CSB B;  1NLJ A;  4PI3 A;  2R9N A;  1NPZ A;  3OF8 A;  2PAD A;  1CTE A;  4BPV A;  2G8J A;  3IMA A;  1BP4 A;  5CVM A;  4PP2 E;  1F29 A;  9PAP A;  2OP3 A;  3PW3 A;  4Q8H A;  2R9F A;  5J94 A;  1POP A;  1EWL A;  4YYU A;  3I06 A;  1PIP A;  1CV8 A;  5CVO B;  6PAD A;  3H6S A;  1MS6 A;  2OUL A;  2XU4 A;  1AEC A;  4Q8G A;  1YVB A;  2O6X A;  4WA6 A;  1TU6 A;  1U9Q X;  1U9W A;  3O1G A;  3KWZ A;  2E00 A;  2Y6E A;  5FPW A;  4YVA A;  1CS8 A;  3BPM A;  4I04 A;  3PBH A;  3P5U A;  2DZZ A;  4P6E A;  1PAD A;  4N8W A;  5CHV A;  5K16 A;  3H8B A;  2F7D A;  2DJF B;  4YV8 A;  2HXZ A; 
#chains in the Genus database with same CATH topology
 1BY8 A;  2R9M A;  3E1Z B;  4CDF B;  4AXM A;  3H89 A;  2FRA A;  3CBJ A;  3KW9 A;  1THE A;  1AYW A;  2JQG R;  1EF7 A;  1PVJ A;  3P5X A;  2FYE A;  3O0U A;  4BOS A;  2AYO A;  2P0R A;  1AIM A;  3RVX A;  5PAD A;  3S3Q A;  4CDD B;  2BDZ A;  1GMY A;  1ICF A;  3PHX A;  2IBI A;  3IEJ A;  4RF1 A;  5F02 A;  3U8E A;  4P6G A;  1NQC A;  4FJC A;  4BOU A;  3ZUA A;  3BC3 A;  3CBK A;  2C0Y A;  3S3R A;  2G6D A;  3N4C A;  3B21 A;  1Y08 A;  1O0E A;  4MSX A;  1F2B A;  3CH3 X;  3I3T A;  4GUA A;  1F2A A;  1YAL A;  2AUZ A;  1Y4H A;  3KFQ A;  3IFU A;  3MTN A;  3MHH A;  2XU5 A;  2FRQ A;  1NB3 A;  2JRI A;  4OEL A;  2Y5B A;  4IUM A;  2E01 A;  2H7J A;  5EGW A;  4FIP A;  1PBH A;  3W31 A;  5EZQ A;  3HD3 A;  4CDE B;  1MEG A;  4N4Z A;  2G7Y A;  1STF E;  2FE8 A;  1S4V A;  3V6C A;  2GFO A;  4BS6 A;  3MHS A;  2E03 A;  3ERV A;  3MTV A;  3HWN A;  3PRP A;  4W4U A;  1GEC E;  5E6J A;  1HUC B;  2DCD A;  1YZB A;  3PDF A;  4BSQ A;  1YT7 A;  2ACT A;  5A24 A;  8PCH A;  3N3G A;  4PT5 A;  1PE6 A;  1U9X A;  4OVZ A;  2DCC A;  4YYW A;  4YYV A;  3OIS A;  3WXG A;  4HXD B;  1KHP A;  2NQG A;  2BU3 A;  2R6N A;  4BQV A;  3HHA A;  1U5I A;  4A5U A;  1IWD A;  1ZIV A;  4KLB A;  4X6H A;  4DMX A;  2FTD A;  3PSE A;  4G54 A;  4RY2 A;  4QBB A;  3NHE A;  1YK7 A;  3PHU A;  2NQI A;  4QRX A;  3C9E A;  4BOP A;  2DZY A;  4W5B A;  3KWB X;  4BS5 A;  4IP3 A;  2DCA A;  1KFX L;  2P7U A;  3LFY A;  4W5C A;  1Q6K A;  2FO5 A;  3PNR A;  3C0R A;  4R3D A;  3F5V A;  2OZ2 A;  3AI8 A;  2E02 A;  3V6E A;  2FQ9 A;  1A6R A;  3BBA A;  3CH2 X;  4PP1 A;  2IPP B;  2CB5 A;  4PAD A;  2FUD A;  4QRG A;  2YJC A;  3PHW A;  3TMP A;  3RVV A;  1AYV A;  1BQI A;  5CHT A;  4CZW A;  3OF9 A;  2DJG B;  1KHQ A;  3OVZ A;  4K7C A;  4RF0 A;  4RKX A;  3ZNH A;  1CJL A;  3H7D A;  4DMY A;  1QXP A;  3MOR A;  4FK5 A;  1ZCM A;  3PRM A;  1MDW A;  1GCB A;  4XUI A;  2G8E A;  2R9C A;  3KKU A;  2DC9 A;  2P86 A;  1X9Y A;  4MI7 A;  2VHF A;  1CB5 A;  1CPJ A;  1K3B B;  1AU2 A;  2B1M A;  3IV2 A;  3KX1 A;  2J7Q C;  1QDQ A;  7PCK A;  1DF0 A;  2J7Q A;  2FT2 A;  2BDL A;  1AU0 A;  4YYS A;  2UZJ A;  3K24 A;  3TNX A;  1VJV A;  1DKI A;  1U9V A;  2PRE A;  3P5W A;  3F75 A;  4X6J A;  3PT2 A;  2BTW A;  3IOQ A;  1QMY A;  3RVW A;  3USV A;  4QRV A;  1DEU A;  1CVZ A;  5JH3 A;  2AIM A;  3BPF A;  1F2C A;  1EWM A;  1AYU A;  3IHP A;  2AVW A;  1PPN A;  1AU4 A;  2DC6 A;  2AUX A;  1EWO A;  4X6I A;  1PPP A;  3B79 A;  1TLO A;  2B1N A;  1EWP A;  5EZS A;  1FH0 A;  2GHU A;  5EF4 A;  1MHW A;  2ATO A;  2WBF X;  3BWK A;  3HHI A;  4XZX A;  1YK8 A;  2CIO A;  2XU1 A;  2NQD B;  5JA7 A;  2NQA A;  2XU3 A;  1QOL A;  2AU1 A;  4N79 A;  3QJ3 A;  4YYQ A;  2Z84 A;  3KSE A;  1ME3 A;  2YJ2 A;  1MEM A;  2PBH A;  4YYR A;  2F1G A;  4BOQ A;  3E9S A;  3QSD A;  3GCB A;  4MZO A;  4OEM A;  2AGA A;  3TRK A;  3K8U A;  2YJB A;  2AS8 A;  2YJ8 A;  1JQP A;  1VSN A;  1GLO A;  4QH6 A;  4RNA A;  3WXE A;  3D6S A;  4XR7 A;  1M6D A;  1KXR A;  3QT4 A;  1NB5 A;  4P16 A;  3BOW A;  3BCN A;  2AYN A;  1XKG A;  4ZTB A;  2DC7 A;  1PPD A;  4MZS A;  3DF0 A;  3WXF A;  1NL6 A;  2VHS A;  1MIR A;  1ME4 A;  2HH5 A;  3BB7 A;  1SNK A;  4OVZ B;  1ATK A;  1AU3 A;  3IUT A;  4OW0 A;  4BOZ A;  5CVN B;  4D8E A;  2YJ9 A;  1BGO A;  2DC8 A;  2JQF R;  3M99 A;  4HWY A;  1PPO A;  1CQD A;  1PXV A;  4D8I A;  3H8C A;  4ZUX U;  3K9M A;  4WUR A;  1TL9 A;  3OVX A;  5JZE A;  2HHN A;  2HD5 A;  4I07 A;  1ITO A;  2PNS A;  2HWK A;  2R9O A;  1SP4 B;  3N3K A;  4AXL A;  1KFU L;  3LXS A;  4CDC B;  2DCB A;  1PCI A;  2ARY A;  4I05 A;  3P5V A;  1CSB B;  1NLJ A;  2JTC A;  4PI3 A;  2R9N A;  1NPZ A;  3OF8 A;  2PAD A;  1CTE A;  4BPV A;  2G8J A;  1UKF A;  3MP2 A;  3IMA A;  1BP4 A;  5CVM A;  4PP2 E;  1F29 A;  3BY4 A;  5KO3 A;  9PAP A;  2OP3 A;  3PW3 A;  4MM3 B;  4Q8H A;  3OQC A;  2R9F A;  4REZ A;  2DOS A;  5J94 A;  1POP A;  1EWL A;  4YYU A;  3I06 A;  1PIP A;  1CV8 A;  5CVO B;  6PAD A;  3W30 A;  3H6S A;  1MS6 A;  2OUL A;  2XU4 A;  1AEC A;  4Q8G A;  1YVB A;  2O6X A;  4WA6 A;  1TU6 A;  1U9Q X;  1U9W A;  3O1G A;  3KWZ A;  2E00 A;  2Y6E A;  3MJ5 A;  4D8B A;  5FPW A;  3O65 A;  1CS8 A;  3BPM A;  4YVA A;  3RNV A;  4I04 A;  3PBH A;  3P5U A;  2DZZ A;  4P6E A;  1PAD A;  4N8W A;  5CHV A;  4M0W A;  5K16 A;  2BTW B;  3H8B A;  2F7D A;  2DJF B;  4YV8 A;  2HXZ A; 
#chains in the Genus database with same CATH homology
 1BY8 A;  2R9M A;  3E1Z B;  4CDF B;  4AXM A;  3H89 A;  2FRA A;  3CBJ A;  3KW9 A;  1THE A;  1AYW A;  2JQG R;  1EF7 A;  3P5X A;  2FYE A;  3O0U A;  2AYO A;  2P0R A;  1AIM A;  3RVX A;  5PAD A;  3S3Q A;  4CDD B;  2BDZ A;  1GMY A;  1ICF A;  2IBI A;  3IEJ A;  1E2T A;  5F02 A;  3U8E A;  4P6G A;  1NQC A;  4FJC A;  3ZUA A;  3BC3 A;  3CBK A;  2C0Y A;  3S3R A;  2G6D A;  3N4C A;  1Y08 A;  1O0E A;  4MSX A;  1F2B A;  3CH3 X;  3I3T A;  1F2A A;  1YAL A;  2AUZ A;  1W5R A;  1Y4H A;  3KFQ A;  3MTN A;  3MHH A;  2XU5 A;  2FRQ A;  1NB3 A;  4OEL A;  2Y5B A;  4NV8 A;  2E01 A;  2H7J A;  5EGW A;  4FIP A;  1PBH A;  3HD3 A;  4CDE B;  1MEG A;  4N4Z A;  2G7Y A;  1STF E;  1S4V A;  3V6C A;  2GFO A;  4BS6 A;  3MHS A;  2E03 A;  3ERV A;  3HWN A;  4W4U A;  1GEC E;  2VFC A;  1HUC B;  4C5P A;  2DCD A;  1GX3 A;  3PDF A;  4BSQ A;  1YT7 A;  2ACT A;  5A24 A;  8PCH A;  3N3G A;  1PE6 A;  1U9X A;  2DCC A;  4YYW A;  4YYV A;  3OIS A;  3WXG A;  1KHP A;  2NQG A;  2R6N A;  4BQV A;  3HHA A;  1U5I A;  1IWD A;  1ZIV A;  4KLB A;  4X6H A;  4NV7 A;  4DMX A;  4B55 A;  2FTD A;  4G54 A;  4RY2 A;  4QBB A;  3NHE A;  1YK7 A;  2NQI A;  4QRX A;  3C9E A;  2DZY A;  4W5B A;  3KWB X;  4BS5 A;  4GUZ A;  2DCA A;  1KFX L;  2P7U A;  3LFY A;  4W5C A;  1Q6K A;  2FO5 A;  3PNR A;  3F5V A;  2OZ2 A;  3AI8 A;  2E02 A;  3V6E A;  2FQ9 A;  1A6R A;  3CH2 X;  4PP1 A;  2IPP B;  2CB5 A;  4PAD A;  2FUD A;  4QRG A;  2YJC A;  3RVV A;  1AYV A;  1BQI A;  5CHT A;  4CZW A;  3OF9 A;  1W4T A;  2DJG B;  1KHQ A;  3OVZ A;  4K7C A;  1CJL A;  3H7D A;  4DMY A;  1QXP A;  3MOR A;  4FK5 A;  1ZCM A;  1MDW A;  1GCB A;  4XUI A;  2G8E A;  2R9C A;  3KKU A;  2DC9 A;  2P86 A;  1X9Y A;  2VHF A;  1CB5 A;  1CPJ A;  1K3B B;  1AU2 A;  2B1M A;  3IV2 A;  3KX1 A;  1QDQ A;  7PCK A;  1DF0 A;  2FT2 A;  2BDL A;  1AU0 A;  4YYS A;  3K24 A;  3TNX A;  1VJV A;  2PRE A;  1U9V A;  1W6F A;  3P5W A;  3F75 A;  4X6J A;  3IOQ A;  1QMY A;  3RVW A;  3USV A;  4QRV A;  1DEU A;  1CVZ A;  5JH3 A;  2AIM A;  3BPF A;  1F2C A;  1EWM A;  1AYU A;  3IHP A;  2AVW A;  1PPN A;  1AU4 A;  2DC6 A;  2AUX A;  1EWO A;  4X6I A;  1PPP A;  3B79 A;  1TLO A;  2B1N A;  1EWP A;  1FH0 A;  2GHU A;  5EF4 A;  1MHW A;  2ATO A;  2WBF X;  3BWK A;  3HHI A;  1YK8 A;  2CIO A;  2XU1 A;  2NQD B;  5JA7 A;  2NQA A;  2XU3 A;  1QOL A;  2AU1 A;  4N79 A;  3QJ3 A;  4YYQ A;  3KSE A;  1ME3 A;  2YJ2 A;  1MEM A;  2PBH A;  4YYR A;  2F1G A;  3QSD A;  3GCB A;  4MZO A;  4OEM A;  3K8U A;  2YJB A;  2AS8 A;  2YJ8 A;  1JQP A;  1VSN A;  1GLO A;  4QH6 A;  3WXE A;  3D6S A;  4XR7 A;  1M6D A;  1KXR A;  3QT4 A;  1NB5 A;  3BOW A;  3BCN A;  2AYN A;  1XKG A;  2DC7 A;  1PPD A;  4MZS A;  3DF0 A;  3WXF A;  1NL6 A;  2VHS A;  1MIR A;  1ME4 A;  2HH5 A;  1SNK A;  1ATK A;  1AU3 A;  3IUT A;  5CVN B;  2YJ9 A;  1BGO A;  2DC8 A;  2JQF R;  3M99 A;  4HWY A;  1PPO A;  1CQD A;  1PXV A;  3H8C A;  4ZUX U;  3K9M A;  1TL9 A;  3OVX A;  2HHN A;  2HD5 A;  4I07 A;  1ITO A;  2PNS A;  2R9O A;  1SP4 B;  3N3K A;  4AXL A;  1KFU L;  3LXS A;  4CDC B;  2DCB A;  1PCI A;  2ARY A;  4I05 A;  3P5V A;  1CSB B;  1NLJ A;  4PI3 A;  2R9N A;  1NPZ A;  3OF8 A;  2PAD A;  1CTE A;  4BPV A;  2G8J A;  3IMA A;  1BP4 A;  5CVM A;  4PP2 E;  1F29 A;  2BSZ A;  9PAP A;  2OP3 A;  3PW3 A;  4Q8H A;  2R9F A;  5J94 A;  1POP A;  1EWL A;  4YYU A;  3I06 A;  1PIP A;  1CV8 A;  3LTW A;  5CVO B;  6PAD A;  3H6S A;  1MS6 A;  2OUL A;  2XU4 A;  1AEC A;  4Q8G A;  1YVB A;  2O6X A;  4WA6 A;  1TU6 A;  1U9Q X;  1U9W A;  4BGF A;  3O1G A;  3KWZ A;  2E00 A;  2Y6E A;  5FPW A;  4YVA A;  1CS8 A;  3BPM A;  4I04 A;  2VFB A;  3PBH A;  3P5U A;  2DZZ A;  4P6E A;  1PAD A;  4N8W A;  5CHV A;  5K16 A;  3H8B A;  2F7D A;  3D9W A;  2DJF B;  4YV8 A;  2HXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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