1U9XA

Crystal structure of the cysteine protease human cathepsin k in complex with the covalent inhibitor nvp-abj688
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
216
structure length
216
Chain Sequence
RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 63
structure length 216
sequence length 216
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2004-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1u9xA00
4OELA 1FH0A 4MZOA 1YVBA 2R6NA 1CJLA 6PADA 1PPNA 3PDFA 2DZYA 2R9CA 3BC3A 1VJVA 4QBBA 3LXSA 1U9VA 3IEJA 4X6JA 3BPFA 1BP4A 2G7YA 4I07A 4Q8HA 2PREA 3MHHA 3H8BA 4YYQA 2H7JA 3O1GA 4N4ZA 2VHSA 2DZZA 4YYVA 3V6EA 2R9FA 3P5XA 1K3BB 2AYOA 1SP4B 1M6DA 2DC8A 1PIPA 3QJ3A 1CV8A 1POPA 1ICFA 2AUXA 2YJCA 2BDZA 2WBFX 1Y08A 2AIMA 3BWKA 4KLBA 4PADA 3P5WA 1QXPA 3NHEA 3WXFA 3OF8A 2E01A 2E02A 1NQCA 1PXVA 4BQVA 3BOWA 4W4UA 3AI8A 1GCBA 4YYRA 1HUCB 3H89A 3IUTA 1U5IA 4N79A 1CB5A 2FTDA 4I05A 1CQDA 3OISA 2FO5A 1MIRA 2P7UA 3I3TA 3HHIA 4CDEB 1TL9A 2P86A 1STFE 2NQAA 5J94A 3N3KA 4W5BA 2XU4A 8PCHA 1BGOA 4CDCB 1U9XA 2PBHA 2NQDB 1MHWA 2CB5A 3H8CA 2GFOA 1AU3A 3WXGA 1GLOA 4N8WA 1F29A 4XR7A 2DC7A 1ZCMA 2Y6EA 4QRGA 1TLOA 4AXLA 1YALA 3F5VA 2B1MA 3K8UA 3HWNA 2XU5A 7PCKA 1KFXL 4QRXA 3RVWA 1THEA 3B79A 1EWOA 3D6SA 2NQIA 3GCBA 1EWPA 2PADA 2AYNA 3ZUAA 2B1NA 2VHFA 3KWBX 1PCIA 2YJ8A 3S3QA 4G54A 2OZ2A 2DJFB 1GECE 1PPPA 2OULA 1MEMA 2R9MA 2HHNA 4OEMA 2DC6A 4P6EA 4AXMA 1KHPA 1AU4A 1DEUA 4FIPA 3HD3A 3N3GA 1CTEA 4YYUA 1CPJA 1MEGA 3KW9A 1NPZA 3ERVA 2C0YA 2IBIA 2DC9A 1YK8A 2CIOA 3CBKA 3PBHA 3E1ZB 4RY2A 4YV8A 1X9YA 1MS6A 1NB5A 2ARYA 3BPMA 3MHSA 4PI3A 4W5CA 2FT2A 1BQIA 1JQPA 1XKGA 1AU0A 3DF0A 1ATKA 1AYVA 2AS8A 3MORA 1AU2A 2PNSA 1ME3A 3WXEA 3K9MA 2R9NA 4K7CA 3HHAA 5CVNB 2R9OA 1YT7A 2FRQA 4CDDB 1NB3A 5JA7A 4CDFB 5CHTA 3H7DA 1A6RA 3IV2A 1NLJA 4MSXA 1EF7A 3TNXA 1O0EA 3QSDA 1EWMA 3P5UA 4YYSA 3KKUA 4BS5A 4DMYA 3BCNA 1CVZA 3CBJA 2G8EA 2O6XA 2AVWA 3O0UA 3KFQA 1KXRA 4HWYA 4BPVA 4ZUXU 4Q8GA 1ZIVA 4BS6A 2HXZA 3RVVA 1PE6A 4BSQA 4PP2E 3IOQA 5K16A 2YJ2A 1AECA 1QDQA 3RVXA 1ITOA 2E03A 5CVOB 2FQ9A 2DCAA 1PADA 5EGWA 2GHUA 5F02A 2YJBA 3PW3A 4QRVA 1MDWA 1PBHA 5A24A 1TU6A 1SNKA 3N4CA 2OP3A 3OVZA 1F2BA 4FJCA 2JQGR 1F2CA 1ME4A 2FYEA 4MZSA 3LFYA 4PP1A 1Y4HA 3KX1A 2NQGA 1S4VA 3IHPA 1NL6A 1BY8A 2DCCA 1GMYA 2G6DA 2E00A 4WA6A 3KWZA 1Q6KA 3V6CA 3CH3X 3OF9A 1KFUL 1IWDA 2BDLA 2XU3A 2ATOA 1QOLA 4YVAA 2XU1A 3K24A 2YJ9A 1DF0A 2JQFR 1AYUA 3QT4A 4X6IA 4QH6A 1PPOA 2Y5BA 3H6SA 4DMXA 1U9WA 1VSNA 3F75A 5CHVA 1F2AA 2G8JA 4CZWA 3CH2X 3OVXA 1AIMA 4XUIA 5PADA 4P6GA 4FK5A 2IPPB 1U9QX 1CS8A 1CSBB 2ACTA 5CVMA 5FPWA 3MTNA 2FUDA 1PPDA 2F7DA 3I06A 2AU1A 3IMAA 2AUZA 1EWLA 3KSEA 2HH5A 2HD5A 3PNRA 3U8EA 2P0RA 2DCBA 1AYWA 2DCDA 1KHQA 3M99A 2F1GA 2FRAA 4YYWA 4I04A 5EF4A 3S3RA 3USVA 5JH3A 1QMYA 2DJGB 3C9EA 1YK7A 3P5VA 4X6HA 9PAPA
chains in the Genus database with same CATH superfamily
4OELA 1FH0A 4MZOA 4XZXA 1YVBA 2R6NA 4BOQA 1CJLA 6PADA 1PPNA 3PDFA 2DZYA 2R9CA 5JZEA 3BC3A 1VJVA 4QBBA 3LXSA 1U9VA 3IEJA 4X6JA 3BPFA 1BP4A 2G7YA 4I07A 4Q8HA 2PREA 3MHHA 4BOZA 3H8BA 4YYQA 2H7JA 3O1GA 4N4ZA 2VHSA 4BOUA 2DZZA 4YYVA 3V6EA 4D8EA 2R9FA 3P5XA 2JRIA 1K3BB 2AYOA 1SP4B 1M6DA 2DC8A 1PIPA 3QJ3A 1CV8A 3PRMA 1POPA 1ICFA 2AUXA 2YJCA 2BDZA 2WBFX 1Y08A 2AIMA 3BWKA 4KLBA 4PADA 3P5WA 1UKFA 1QXPA 3NHEA 3WXFA 3OF8A 2DOSA 2E01A 2E02A 1NQCA 4OVZB 1PXVA 4BQVA 3IFUA 3BOWA 4W4UA 3AI8A 1GCBA 4YYRA 1HUCB 3H89A 3IUTA 2BTWA 1U5IA 4N79A 3W31A 1CB5A 2FTDA 4I05A 1CQDA 3OISA 2FO5A 1MIRA 2P7UA 3I3TA 3HHIA 4CDEB 1TL9A 2P86A 1STFE 2NQAA 5J94A 3N3KA 4W5BA 2XU4A 8PCHA 1BGOA 4CDCB 1U9XA 2PBHA 2NQDB 1MHWA 2CB5A 3H8CA 2GFOA 1AU3A 3WXGA 3PHWA 1GLOA 4RKXA 4N8WA 1F29A 4XR7A 2DC7A 1ZCMA 2Y6EA 4QRGA 1TLOA 4AXLA 1YALA 3F5VA 2B1MA 3K8UA 3HWNA 2XU5A 3PT2A 7PCKA 1KFXL 4QRXA 3RVWA 1THEA 3B79A 1EWOA 3D6SA 4D8IA 2NQIA 3GCBA 1EWPA 2PADA 4OVZA 2AYNA 3ZUAA 1DKIA 2B1NA 2VHFA 3KWBX 1PCIA 2YJ8A 3S3QA 4G54A 2OZ2A 2DJFB 1GECE 1PPPA 2OULA 3ZNHA 1MEMA 2R9MA 2HHNA 4OEMA 2DC6A 4P6EA 4AXMA 1KHPA 1AU4A 1DEUA 4FIPA 3HD3A 3N3GA 1CTEA 4YYUA 1CPJA 1MEGA 3KW9A 1NPZA 3ERVA 2C0YA 2IBIA 2DC9A 1YK8A 2CIOA 2J7QA 3CBKA 3E9SA 3PBHA 3E1ZB 4RY2A 1PVJA 5E6JA 2FE8A 4YV8A 1X9YA 3MP2A 1MS6A 4M0WA 1NB5A 2ARYA 3BPMA 3MHSA 4WURA 4PI3A 4W5CA 2FT2A 1BQIA 1JQPA 1XKGA 1AU0A 3DF0A 1ATKA 1AYVA 5EZQA 2AS8A 4A5UA 5EZSA 3MORA 3OQCA 4RF1A 1AU2A 2PNSA 3TRKA 1ME3A 3MTVA 4HXDB 3WXEA 3K9MA 2R9NA 4K7CA 3HHAA 5CVNB 2R9OA 1YT7A 2FRQA 4CDDB 1NB3A 3W30A 5JA7A 4CDFB 5CHTA 3H7DA 1A6RA 3IV2A 1NLJA 4MSXA 1EF7A 3TNXA 1O0EA 3QSDA 5KO3A 1EWMA 3P5UA 4YYSA 3KKUA 4BS5A 4DMYA 3B21A 3BCNA 1CVZA 3CBJA 2G8EA 3BY4A 2O6XA 2AVWA 3O0UA 3KFQA 1KXRA 4HWYA 4BPVA 4ZUXU 4Q8GA 1ZIVA 4BS6A 2HXZA 3RVVA 1PE6A 3MJ5A 4BSQA 4IUMA 4GUAA 4PP2E 3IOQA 4MI7A 2YJ2A 5K16A 1AECA 1QDQA 4RF0A 3RVXA 1ITOA 2E03A 5CVOB 2FQ9A 2DCAA 1PADA 5EGWA 2GHUA 5F02A 2YJBA 3PW3A 4QRVA 1MDWA 1PBHA 5A24A 1TU6A 1SNKA 4MM3B 3N4CA 2BTWB 2OP3A 3OVZA 1F2BA 3O65A 4FJCA 2JQGR 1F2CA 1ME4A 2FYEA 4MZSA 2AGAA 3LFYA 4PP1A 1Y4HA 3KX1A 2NQGA 1S4VA 3IHPA 3PHUA 1NL6A 3BB7A 1BY8A 2DCCA 1GMYA 2G6DA 2E00A 4OW0A 4WA6A 2UZJA 3KWZA 3TMPA 1Q6KA 3V6CA 3CH3X 3OF9A 1KFUL 2BU3A 1IWDA 2BDLA 2XU3A 4BOSA 2ATOA 1QOLA 4YVAA 2XU1A 3K24A 4R3DA 2YJ9A 1DF0A 3PRPA 1YZBA 2JQFR 3RNVA 1AYUA 3QT4A 4BOPA 4X6IA 4QH6A 1PPOA 2Y5BA 3H6SA 4DMXA 1U9WA 1VSNA 3F75A 5CHVA 1F2AA 2G8JA 4PT5A 2JTCA 4CZWA 3CH2X 3OVXA 3C0RA 1AIMA 4XUIA 5PADA 4P6GA 4FK5A 2IPPB 1U9QX 1CS8A 1CSBB 2ACTA 5CVMA 5FPWA 3MTNA 2FUDA 1PPDA 4IP3A 2F7DA 3I06A 4REZA 2AU1A 3IMAA 3BBAA 4ZTBA 4D8BA 2AUZA 3PHXA 1EWLA 3KSEA 2HH5A 2HD5A 3PNRA 3U8EA 2P0RA 2DCBA 1AYWA 2DCDA 2HWKA 2J7QC 2Z84A 1KHQA 3M99A 2F1GA 2FRAA 4YYWA 4I04A 3PSEA 4RNAA 4P16A 5EF4A 3S3RA 3USVA 5JH3A 1QMYA 2DJGB 3C9EA 1YK7A 3P5VA 4X6HA 9PAPA
chains in the Genus database with same CATH topology
4OELA 1FH0A 4MZOA 1YVBA 2R6NA 1CJLA 6PADA 1PPNA 3PDFA 2DZYA 2R9CA 3BC3A 1VJVA 4QBBA 3LXSA 1U9VA 3IEJA 4X6JA 3BPFA 1BP4A 2G7YA 4I07A 4Q8HA 2PREA 3MHHA 3H8BA 4YYQA 2H7JA 3O1GA 4N4ZA 2VHSA 2DZZA 4YYVA 3V6EA 2R9FA 3P5XA 1K3BB 2AYOA 1SP4B 1M6DA 2DC8A 1PIPA 3QJ3A 1CV8A 1E2TA 1POPA 1ICFA 2AUXA 2YJCA 2BSZA 2BDZA 2WBFX 1Y08A 1W6FA 2AIMA 3BWKA 4KLBA 4PADA 3P5WA 1QXPA 3NHEA 3WXFA 3OF8A 2E01A 2E02A 1NQCA 1PXVA 4BQVA 3BOWA 4W4UA 3AI8A 1GCBA 4YYRA 1HUCB 3H89A 3IUTA 1U5IA 4N79A 1CB5A 2FTDA 4I05A 1CQDA 3OISA 2FO5A 1MIRA 2P7UA 3I3TA 3HHIA 4CDEB 1TL9A 2P86A 1STFE 2NQAA 5J94A 3N3KA 4W5BA 2XU4A 8PCHA 1BGOA 4CDCB 1U9XA 2PBHA 2NQDB 1MHWA 1W5RA 2CB5A 3H8CA 2GFOA 1AU3A 3WXGA 1GLOA 4N8WA 1F29A 4XR7A 2DC7A 1ZCMA 2Y6EA 4QRGA 1TLOA 4AXLA 1YALA 3F5VA 2B1MA 3K8UA 3HWNA 2XU5A 7PCKA 1KFXL 4QRXA 3RVWA 1THEA 3B79A 1EWOA 3D6SA 2NQIA 3GCBA 1EWPA 2PADA 2AYNA 3ZUAA 2B1NA 2VHFA 3KWBX 1PCIA 2YJ8A 3S3QA 4G54A 2OZ2A 2DJFB 1GECE 1PPPA 2OULA 1MEMA 2R9MA 2HHNA 4OEMA 2DC6A 4P6EA 4AXMA 1KHPA 1AU4A 1DEUA 4FIPA 3HD3A 3N3GA 1CTEA 4YYUA 1CPJA 1MEGA 3KW9A 1NPZA 3ERVA 2C0YA 2IBIA 2DC9A 1YK8A 2CIOA 3CBKA 3PBHA 3E1ZB 4RY2A 4YV8A 1X9YA 1MS6A 1NB5A 2ARYA 3BPMA 3MHSA 4PI3A 4W5CA 2FT2A 1BQIA 1JQPA 1W4TA 1XKGA 1AU0A 3DF0A 1ATKA 1AYVA 2AS8A 3MORA 1AU2A 2PNSA 1ME3A 2VFCA 3WXEA 3K9MA 2R9NA 4K7CA 3HHAA 5CVNB 2R9OA 1YT7A 2FRQA 4CDDB 1NB3A 4GUZA 5JA7A 4CDFB 5CHTA 3H7DA 1A6RA 1GX3A 3IV2A 1NLJA 4MSXA 1EF7A 3TNXA 1O0EA 3QSDA 1EWMA 3P5UA 4YYSA 3KKUA 4BS5A 4DMYA 3BCNA 1CVZA 3CBJA 2G8EA 2O6XA 2AVWA 3O0UA 3KFQA 1KXRA 4HWYA 4BPVA 4ZUXU 4BGFA 4Q8GA 1ZIVA 4BS6A 2HXZA 3RVVA 1PE6A 4BSQA 4PP2E 3IOQA 5K16A 2YJ2A 1AECA 1QDQA 3RVXA 1ITOA 2E03A 5CVOB 2FQ9A 2DCAA 1PADA 5EGWA 2GHUA 5F02A 2YJBA 3PW3A 4QRVA 1MDWA 1PBHA 5A24A 1TU6A 1SNKA 3N4CA 2OP3A 4B55A 3OVZA 1F2BA 2VFBA 4FJCA 2JQGR 1F2CA 1ME4A 2FYEA 4MZSA 3LFYA 4PP1A 1Y4HA 3KX1A 2NQGA 1S4VA 3IHPA 1NL6A 1BY8A 2DCCA 1GMYA 4C5PA 2G6DA 2E00A 4WA6A 3KWZA 1Q6KA 3V6CA 3CH3X 3OF9A 1KFUL 1IWDA 2BDLA 2XU3A 2ATOA 1QOLA 4YVAA 2XU1A 3K24A 2YJ9A 1DF0A 2JQFR 1AYUA 4NV8A 3QT4A 4X6IA 4QH6A 1PPOA 2Y5BA 3H6SA 4DMXA 1U9WA 1VSNA 3F75A 5CHVA 1F2AA 2G8JA 4CZWA 3CH2X 3OVXA 1AIMA 4XUIA 5PADA 4P6GA 4FK5A 2IPPB 1U9QX 1CS8A 1CSBB 2ACTA 4NV7A 5CVMA 5FPWA 3MTNA 2FUDA 1PPDA 2F7DA 3I06A 2AU1A 3IMAA 3LTWA 2AUZA 1EWLA 3KSEA 2HH5A 2HD5A 3PNRA 3U8EA 2P0RA 2DCBA 1AYWA 2DCDA 1KHQA 3M99A 2F1GA 2FRAA 4YYWA 4I04A 3D9WA 5EF4A 3S3RA 3USVA 5JH3A 1QMYA 2DJGB 3C9EA 1YK7A 3P5VA 4X6HA 9PAPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OEL A;  1FH0 A;  4MZO A;  1YVB A;  2R6N A;  1CJL A;  6PAD A;  1PPN A;  3PDF A;  2DZY A;  2R9C A;  3BC3 A;  1VJV A;  4QBB A;  3LXS A;  1U9V A;  3IEJ A;  4X6J A;  3BPF A;  1BP4 A;  2G7Y A;  4I07 A;  4Q8H A;  2PRE A;  3MHH A;  3H8B A;  4YYQ A;  2H7J A;  3O1G A;  4N4Z A;  2VHS A;  2DZZ A;  4YYV A;  3V6E A;  2R9F A;  3P5X A;  1K3B B;  2AYO A;  1SP4 B;  1M6D A;  2DC8 A;  1PIP A;  3QJ3 A;  1CV8 A;  1POP A;  1ICF A;  2AUX A;  2YJC A;  2BDZ A;  2WBF X;  1Y08 A;  2AIM A;  3BWK A;  4KLB A;  4PAD A;  3P5W A;  1QXP A;  3NHE A;  3WXF A;  3OF8 A;  2E01 A;  2E02 A;  1NQC A;  1PXV A;  4BQV A;  3BOW A;  4W4U A;  3AI8 A;  1GCB A;  4YYR A;  1HUC B;  3H89 A;  3IUT A;  1U5I A;  4N79 A;  1CB5 A;  2FTD A;  4I05 A;  1CQD A;  3OIS A;  2FO5 A;  1MIR A;  2P7U A;  3I3T A;  3HHI A;  4CDE B;  1TL9 A;  2P86 A;  1STF E;  2NQA A;  5J94 A;  3N3K A;  4W5B A;  2XU4 A;  8PCH A;  1BGO A;  4CDC B;  1U9X A;  2PBH A;  2NQD B;  1MHW A;  2CB5 A;  3H8C A;  2GFO A;  1AU3 A;  3WXG A;  1GLO A;  4N8W A;  1F29 A;  4XR7 A;  2DC7 A;  1ZCM A;  2Y6E A;  4QRG A;  1TLO A;  4AXL A;  1YAL A;  3F5V A;  2B1M A;  3K8U A;  3HWN A;  2XU5 A;  7PCK A;  1KFX L;  4QRX A;  3RVW A;  1THE A;  3B79 A;  1EWO A;  3D6S A;  2NQI A;  3GCB A;  1EWP A;  2PAD A;  2AYN A;  3ZUA A;  2B1N A;  2VHF A;  3KWB X;  1PCI A;  2YJ8 A;  3S3Q A;  4G54 A;  2OZ2 A;  2DJF B;  1GEC E;  1PPP A;  2OUL A;  1MEM A;  2R9M A;  2HHN A;  4OEM A;  2DC6 A;  4P6E A;  4AXM A;  1KHP A;  1AU4 A;  1DEU A;  4FIP A;  3HD3 A;  3N3G A;  1CTE A;  4YYU A;  1CPJ A;  1MEG A;  3KW9 A;  1NPZ A;  3ERV A;  2C0Y A;  2IBI A;  2DC9 A;  1YK8 A;  2CIO A;  3CBK A;  3PBH A;  3E1Z B;  4RY2 A;  4YV8 A;  1X9Y A;  1MS6 A;  1NB5 A;  2ARY A;  3BPM A;  3MHS A;  4PI3 A;  4W5C A;  2FT2 A;  1BQI A;  1JQP A;  1XKG A;  1AU0 A;  3DF0 A;  1ATK A;  1AYV A;  2AS8 A;  3MOR A;  1AU2 A;  2PNS A;  1ME3 A;  3WXE A;  3K9M A;  2R9N A;  4K7C A;  3HHA A;  5CVN B;  2R9O A;  1YT7 A;  2FRQ A;  4CDD B;  1NB3 A;  5JA7 A;  4CDF B;  5CHT A;  3H7D A;  1A6R A;  3IV2 A;  1NLJ A;  4MSX A;  1EF7 A;  3TNX A;  1O0E A;  3QSD A;  1EWM A;  3P5U A;  4YYS A;  3KKU A;  4BS5 A;  4DMY A;  3BCN A;  1CVZ A;  3CBJ A;  2G8E A;  2O6X A;  2AVW A;  3O0U A;  3KFQ A;  1KXR A;  4HWY A;  4BPV A;  4ZUX U;  4Q8G A;  1ZIV A;  4BS6 A;  2HXZ A;  3RVV A;  1PE6 A;  4BSQ A;  4PP2 E;  3IOQ A;  5K16 A;  2YJ2 A;  1AEC A;  1QDQ A;  3RVX A;  1ITO A;  2E03 A;  5CVO B;  2FQ9 A;  2DCA A;  1PAD A;  5EGW A;  2GHU A;  5F02 A;  2YJB A;  3PW3 A;  4QRV A;  1MDW A;  1PBH A;  5A24 A;  1TU6 A;  1SNK A;  3N4C A;  2OP3 A;  3OVZ A;  1F2B A;  4FJC A;  2JQG R;  1F2C A;  1ME4 A;  2FYE A;  4MZS A;  3LFY A;  4PP1 A;  1Y4H A;  3KX1 A;  2NQG A;  1S4V A;  3IHP A;  1NL6 A;  1BY8 A;  2DCC A;  1GMY A;  2G6D A;  2E00 A;  4WA6 A;  3KWZ A;  1Q6K A;  3V6C A;  3CH3 X;  3OF9 A;  1KFU L;  1IWD A;  2BDL A;  2XU3 A;  2ATO A;  1QOL A;  4YVA A;  2XU1 A;  3K24 A;  2YJ9 A;  1DF0 A;  2JQF R;  1AYU A;  3QT4 A;  4X6I A;  4QH6 A;  1PPO A;  2Y5B A;  3H6S A;  4DMX A;  1U9W A;  1VSN A;  3F75 A;  5CHV A;  1F2A A;  2G8J A;  4CZW A;  3CH2 X;  3OVX A;  1AIM A;  4XUI A;  5PAD A;  4P6G A;  4FK5 A;  2IPP B;  1U9Q X;  1CS8 A;  1CSB B;  2ACT A;  5CVM A;  5FPW A;  3MTN A;  2FUD A;  1PPD A;  2F7D A;  3I06 A;  2AU1 A;  3IMA A;  2AUZ A;  1EWL A;  3KSE A;  2HH5 A;  2HD5 A;  3PNR A;  3U8E A;  2P0R A;  2DCB A;  1AYW A;  2DCD A;  1KHQ A;  3M99 A;  2F1G A;  2FRA A;  4YYW A;  4I04 A;  5EF4 A;  3S3R A;  3USV A;  5JH3 A;  1QMY A;  2DJG B;  3C9E A;  1YK7 A;  3P5V A;  4X6H A;  9PAP A; 
#chains in the Genus database with same CATH topology
 4OEL A;  1FH0 A;  4MZO A;  4XZX A;  1YVB A;  2R6N A;  4BOQ A;  1CJL A;  6PAD A;  1PPN A;  3PDF A;  2DZY A;  2R9C A;  5JZE A;  3BC3 A;  1VJV A;  4QBB A;  3LXS A;  1U9V A;  3IEJ A;  4X6J A;  3BPF A;  1BP4 A;  2G7Y A;  4I07 A;  4Q8H A;  2PRE A;  3MHH A;  4BOZ A;  3H8B A;  4YYQ A;  2H7J A;  3O1G A;  4N4Z A;  2VHS A;  4BOU A;  2DZZ A;  4YYV A;  3V6E A;  4D8E A;  2R9F A;  3P5X A;  2JRI A;  1K3B B;  2AYO A;  1SP4 B;  1M6D A;  2DC8 A;  1PIP A;  3QJ3 A;  1CV8 A;  3PRM A;  1POP A;  1ICF A;  2AUX A;  2YJC A;  2BDZ A;  2WBF X;  1Y08 A;  2AIM A;  3BWK A;  4KLB A;  4PAD A;  3P5W A;  1UKF A;  1QXP A;  3NHE A;  3WXF A;  3OF8 A;  2DOS A;  2E01 A;  2E02 A;  1NQC A;  4OVZ B;  1PXV A;  4BQV A;  3IFU A;  3BOW A;  4W4U A;  3AI8 A;  1GCB A;  4YYR A;  1HUC B;  3H89 A;  3IUT A;  2BTW A;  1U5I A;  4N79 A;  3W31 A;  1CB5 A;  2FTD A;  4I05 A;  1CQD A;  3OIS A;  2FO5 A;  1MIR A;  2P7U A;  3I3T A;  3HHI A;  4CDE B;  1TL9 A;  2P86 A;  1STF E;  2NQA A;  5J94 A;  3N3K A;  4W5B A;  2XU4 A;  8PCH A;  1BGO A;  4CDC B;  1U9X A;  2PBH A;  2NQD B;  1MHW A;  2CB5 A;  3H8C A;  2GFO A;  1AU3 A;  3WXG A;  3PHW A;  1GLO A;  4RKX A;  4N8W A;  1F29 A;  4XR7 A;  2DC7 A;  1ZCM A;  2Y6E A;  4QRG A;  1TLO A;  4AXL A;  1YAL A;  3F5V A;  2B1M A;  3K8U A;  3HWN A;  2XU5 A;  3PT2 A;  7PCK A;  1KFX L;  4QRX A;  3RVW A;  1THE A;  3B79 A;  1EWO A;  3D6S A;  4D8I A;  2NQI A;  3GCB A;  1EWP A;  2PAD A;  4OVZ A;  2AYN A;  3ZUA A;  1DKI A;  2B1N A;  2VHF A;  3KWB X;  1PCI A;  2YJ8 A;  3S3Q A;  4G54 A;  2OZ2 A;  2DJF B;  1GEC E;  1PPP A;  2OUL A;  3ZNH A;  1MEM A;  2R9M A;  2HHN A;  4OEM A;  2DC6 A;  4P6E A;  4AXM A;  1KHP A;  1AU4 A;  1DEU A;  4FIP A;  3HD3 A;  3N3G A;  1CTE A;  4YYU A;  1CPJ A;  1MEG A;  3KW9 A;  1NPZ A;  3ERV A;  2C0Y A;  2IBI A;  2DC9 A;  1YK8 A;  2CIO A;  2J7Q A;  3CBK A;  3E9S A;  3PBH A;  3E1Z B;  4RY2 A;  1PVJ A;  5E6J A;  2FE8 A;  4YV8 A;  1X9Y A;  3MP2 A;  1MS6 A;  4M0W A;  1NB5 A;  2ARY A;  3BPM A;  3MHS A;  4WUR A;  4PI3 A;  4W5C A;  2FT2 A;  1BQI A;  1JQP A;  1XKG A;  1AU0 A;  3DF0 A;  1ATK A;  1AYV A;  5EZQ A;  2AS8 A;  4A5U A;  5EZS A;  3MOR A;  3OQC A;  4RF1 A;  1AU2 A;  2PNS A;  3TRK A;  1ME3 A;  3MTV A;  4HXD B;  3WXE A;  3K9M A;  2R9N A;  4K7C A;  3HHA A;  5CVN B;  2R9O A;  1YT7 A;  2FRQ A;  4CDD B;  1NB3 A;  3W30 A;  5JA7 A;  4CDF B;  5CHT A;  3H7D A;  1A6R A;  3IV2 A;  1NLJ A;  4MSX A;  1EF7 A;  3TNX A;  1O0E A;  3QSD A;  5KO3 A;  1EWM A;  3P5U A;  4YYS A;  3KKU A;  4BS5 A;  4DMY A;  3B21 A;  3BCN A;  1CVZ A;  3CBJ A;  2G8E A;  3BY4 A;  2O6X A;  2AVW A;  3O0U A;  3KFQ A;  1KXR A;  4HWY A;  4BPV A;  4ZUX U;  4Q8G A;  1ZIV A;  4BS6 A;  2HXZ A;  3RVV A;  1PE6 A;  3MJ5 A;  4BSQ A;  4IUM A;  4GUA A;  4PP2 E;  3IOQ A;  4MI7 A;  2YJ2 A;  5K16 A;  1AEC A;  1QDQ A;  4RF0 A;  3RVX A;  1ITO A;  2E03 A;  5CVO B;  2FQ9 A;  2DCA A;  1PAD A;  5EGW A;  2GHU A;  5F02 A;  2YJB A;  3PW3 A;  4QRV A;  1MDW A;  1PBH A;  5A24 A;  1TU6 A;  1SNK A;  4MM3 B;  3N4C A;  2BTW B;  2OP3 A;  3OVZ A;  1F2B A;  3O65 A;  4FJC A;  2JQG R;  1F2C A;  1ME4 A;  2FYE A;  4MZS A;  2AGA A;  3LFY A;  4PP1 A;  1Y4H A;  3KX1 A;  2NQG A;  1S4V A;  3IHP A;  3PHU A;  1NL6 A;  3BB7 A;  1BY8 A;  2DCC A;  1GMY A;  2G6D A;  2E00 A;  4OW0 A;  4WA6 A;  2UZJ A;  3KWZ A;  3TMP A;  1Q6K A;  3V6C A;  3CH3 X;  3OF9 A;  1KFU L;  2BU3 A;  1IWD A;  2BDL A;  2XU3 A;  4BOS A;  2ATO A;  1QOL A;  4YVA A;  2XU1 A;  3K24 A;  4R3D A;  2YJ9 A;  1DF0 A;  3PRP A;  1YZB A;  2JQF R;  3RNV A;  1AYU A;  3QT4 A;  4BOP A;  4X6I A;  4QH6 A;  1PPO A;  2Y5B A;  3H6S A;  4DMX A;  1U9W A;  1VSN A;  3F75 A;  5CHV A;  1F2A A;  2G8J A;  4PT5 A;  2JTC A;  4CZW A;  3CH2 X;  3OVX A;  3C0R A;  1AIM A;  4XUI A;  5PAD A;  4P6G A;  4FK5 A;  2IPP B;  1U9Q X;  1CS8 A;  1CSB B;  2ACT A;  5CVM A;  5FPW A;  3MTN A;  2FUD A;  1PPD A;  4IP3 A;  2F7D A;  3I06 A;  4REZ A;  2AU1 A;  3IMA A;  3BBA A;  4ZTB A;  4D8B A;  2AUZ A;  3PHX A;  1EWL A;  3KSE A;  2HH5 A;  2HD5 A;  3PNR A;  3U8E A;  2P0R A;  2DCB A;  1AYW A;  2DCD A;  2HWK A;  2J7Q C;  2Z84 A;  1KHQ A;  3M99 A;  2F1G A;  2FRA A;  4YYW A;  4I04 A;  3PSE A;  4RNA A;  4P16 A;  5EF4 A;  3S3R A;  3USV A;  5JH3 A;  1QMY A;  2DJG B;  3C9E A;  1YK7 A;  3P5V A;  4X6H A;  9PAP A; 
#chains in the Genus database with same CATH homology
 4OEL A;  1FH0 A;  4MZO A;  1YVB A;  2R6N A;  1CJL A;  6PAD A;  1PPN A;  3PDF A;  2DZY A;  2R9C A;  3BC3 A;  1VJV A;  4QBB A;  3LXS A;  1U9V A;  3IEJ A;  4X6J A;  3BPF A;  1BP4 A;  2G7Y A;  4I07 A;  4Q8H A;  2PRE A;  3MHH A;  3H8B A;  4YYQ A;  2H7J A;  3O1G A;  4N4Z A;  2VHS A;  2DZZ A;  4YYV A;  3V6E A;  2R9F A;  3P5X A;  1K3B B;  2AYO A;  1SP4 B;  1M6D A;  2DC8 A;  1PIP A;  3QJ3 A;  1CV8 A;  1E2T A;  1POP A;  1ICF A;  2AUX A;  2YJC A;  2BSZ A;  2BDZ A;  2WBF X;  1Y08 A;  1W6F A;  2AIM A;  3BWK A;  4KLB A;  4PAD A;  3P5W A;  1QXP A;  3NHE A;  3WXF A;  3OF8 A;  2E01 A;  2E02 A;  1NQC A;  1PXV A;  4BQV A;  3BOW A;  4W4U A;  3AI8 A;  1GCB A;  4YYR A;  1HUC B;  3H89 A;  3IUT A;  1U5I A;  4N79 A;  1CB5 A;  2FTD A;  4I05 A;  1CQD A;  3OIS A;  2FO5 A;  1MIR A;  2P7U A;  3I3T A;  3HHI A;  4CDE B;  1TL9 A;  2P86 A;  1STF E;  2NQA A;  5J94 A;  3N3K A;  4W5B A;  2XU4 A;  8PCH A;  1BGO A;  4CDC B;  1U9X A;  2PBH A;  2NQD B;  1MHW A;  1W5R A;  2CB5 A;  3H8C A;  2GFO A;  1AU3 A;  3WXG A;  1GLO A;  4N8W A;  1F29 A;  4XR7 A;  2DC7 A;  1ZCM A;  2Y6E A;  4QRG A;  1TLO A;  4AXL A;  1YAL A;  3F5V A;  2B1M A;  3K8U A;  3HWN A;  2XU5 A;  7PCK A;  1KFX L;  4QRX A;  3RVW A;  1THE A;  3B79 A;  1EWO A;  3D6S A;  2NQI A;  3GCB A;  1EWP A;  2PAD A;  2AYN A;  3ZUA A;  2B1N A;  2VHF A;  3KWB X;  1PCI A;  2YJ8 A;  3S3Q A;  4G54 A;  2OZ2 A;  2DJF B;  1GEC E;  1PPP A;  2OUL A;  1MEM A;  2R9M A;  2HHN A;  4OEM A;  2DC6 A;  4P6E A;  4AXM A;  1KHP A;  1AU4 A;  1DEU A;  4FIP A;  3HD3 A;  3N3G A;  1CTE A;  4YYU A;  1CPJ A;  1MEG A;  3KW9 A;  1NPZ A;  3ERV A;  2C0Y A;  2IBI A;  2DC9 A;  1YK8 A;  2CIO A;  3CBK A;  3PBH A;  3E1Z B;  4RY2 A;  4YV8 A;  1X9Y A;  1MS6 A;  1NB5 A;  2ARY A;  3BPM A;  3MHS A;  4PI3 A;  4W5C A;  2FT2 A;  1BQI A;  1JQP A;  1W4T A;  1XKG A;  1AU0 A;  3DF0 A;  1ATK A;  1AYV A;  2AS8 A;  3MOR A;  1AU2 A;  2PNS A;  1ME3 A;  2VFC A;  3WXE A;  3K9M A;  2R9N A;  4K7C A;  3HHA A;  5CVN B;  2R9O A;  1YT7 A;  2FRQ A;  4CDD B;  1NB3 A;  4GUZ A;  5JA7 A;  4CDF B;  5CHT A;  3H7D A;  1A6R A;  1GX3 A;  3IV2 A;  1NLJ A;  4MSX A;  1EF7 A;  3TNX A;  1O0E A;  3QSD A;  1EWM A;  3P5U A;  4YYS A;  3KKU A;  4BS5 A;  4DMY A;  3BCN A;  1CVZ A;  3CBJ A;  2G8E A;  2O6X A;  2AVW A;  3O0U A;  3KFQ A;  1KXR A;  4HWY A;  4BPV A;  4ZUX U;  4BGF A;  4Q8G A;  1ZIV A;  4BS6 A;  2HXZ A;  3RVV A;  1PE6 A;  4BSQ A;  4PP2 E;  3IOQ A;  5K16 A;  2YJ2 A;  1AEC A;  1QDQ A;  3RVX A;  1ITO A;  2E03 A;  5CVO B;  2FQ9 A;  2DCA A;  1PAD A;  5EGW A;  2GHU A;  5F02 A;  2YJB A;  3PW3 A;  4QRV A;  1MDW A;  1PBH A;  5A24 A;  1TU6 A;  1SNK A;  3N4C A;  2OP3 A;  4B55 A;  3OVZ A;  1F2B A;  2VFB A;  4FJC A;  2JQG R;  1F2C A;  1ME4 A;  2FYE A;  4MZS A;  3LFY A;  4PP1 A;  1Y4H A;  3KX1 A;  2NQG A;  1S4V A;  3IHP A;  1NL6 A;  1BY8 A;  2DCC A;  1GMY A;  4C5P A;  2G6D A;  2E00 A;  4WA6 A;  3KWZ A;  1Q6K A;  3V6C A;  3CH3 X;  3OF9 A;  1KFU L;  1IWD A;  2BDL A;  2XU3 A;  2ATO A;  1QOL A;  4YVA A;  2XU1 A;  3K24 A;  2YJ9 A;  1DF0 A;  2JQF R;  1AYU A;  4NV8 A;  3QT4 A;  4X6I A;  4QH6 A;  1PPO A;  2Y5B A;  3H6S A;  4DMX A;  1U9W A;  1VSN A;  3F75 A;  5CHV A;  1F2A A;  2G8J A;  4CZW A;  3CH2 X;  3OVX A;  1AIM A;  4XUI A;  5PAD A;  4P6G A;  4FK5 A;  2IPP B;  1U9Q X;  1CS8 A;  1CSB B;  2ACT A;  4NV7 A;  5CVM A;  5FPW A;  3MTN A;  2FUD A;  1PPD A;  2F7D A;  3I06 A;  2AU1 A;  3IMA A;  3LTW A;  2AUZ A;  1EWL A;  3KSE A;  2HH5 A;  2HD5 A;  3PNR A;  3U8E A;  2P0R A;  2DCB A;  1AYW A;  2DCD A;  1KHQ A;  3M99 A;  2F1G A;  2FRA A;  4YYW A;  4I04 A;  3D9W A;  5EF4 A;  3S3R A;  3USV A;  5JH3 A;  1QMY A;  2DJG B;  3C9E A;  1YK7 A;  3P5V A;  4X6H A;  9PAP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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