1U9XA

Crystal structure of the cysteine protease human cathepsin k in complex with the covalent inhibitor nvp-abj688
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
216
structure length
216
Chain Sequence
RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 63
structure length 216
sequence length 216
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2004-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1u9xA00
4I05A 3KW9A 1F2AA 3IEJA 1EWPA 1MDWA 4OELA 3ZUAA 1YALA 5JA7A 2B1MA 2DC6A 4RY2A 3HHAA 4OEMA 5JH3A 2C0YA 2DCDA 1CTEA 3GCBA 1ME3A 1NLJA 4W5CA 1QDQA 4Q8HA 1CS8A 4FK5A 3IV2A 1F2CA 4G54A 3CBKA 2P86A 2NQAA 2ARYA 1SP4B 4QBBA 3I06A 1NL6A 3KFQA 1U9VA 3N4CA 3K24A 1AYVA 2B1NA 3ERVA 2AS8A 3MORA 1FH0A 2FRQA 2HXZA 1PPDA 4BQVA 4XR7A 2OP3A 4W4UA 1YVBA 1K3BB 2DC9A 1XKGA 3S3RA 3BC3A 4QRVA 5CHVA 1PPNA 4PI3A 3WXGA 3PBHA 3AI8A 3O1GA 1Y08A 4AXMA 1QXPA 4MZSA 3HD3A 3H8CA 3RVWA 1PIPA 2DJGB 2GFOA 3P5UA 4N79A 5EF4A 3RVXA 2G6DA 2XU3A 2BDZA 1MEGA 3WXFA 3S3QA 3CBJA 2DCBA 3USVA 4CZWA 8PCHA 1Q6KA 2YJ8A 4QRXA 4X6HA 3OISA 4YYQA 3OF9A 1VJVA 4MSXA 2BDLA 1U9QX 1QMYA 4X6IA 1TL9A 2ATOA 3F75A 4P6GA 1CVZA 2DZZA 3HHIA 4PP2E 2AIMA 1GECE 4PADA 1VSNA 3BPMA 5J94A 1M6DA 3V6EA 1GMYA 3U8EA 4Q8GA 2P7UA 1AU4A 1DEUA 2R9OA 3H8BA 4CDDB 4YYVA 1EF7A 3KX1A 3V6CA 3KKUA 4YYWA 1PBHA 2DCCA 2G8JA 4DMYA 2VHFA 2FT2A 4N8WA 2JQFR 1NPZA 2R9CA 2R6NA 4W5BA 3BOWA 1PCIA 1PXVA 1A6RA 1MIRA 3HWNA 3QSDA 1YK8A 1ME4A 2HD5A 4YVAA 2JQGR 3NHEA 3PW3A 1KFXL 3TNXA 5FPWA 1CB5A 2AU1A 1BY8A 2YJ2A 2FRAA 3BCNA 3DF0A 3P5WA 1CJLA 4BSQA 1HUCB 2OZ2A 2HHNA 5CVOB 4K7CA 3CH2X 6PADA 3BWKA 4I04A 4N4ZA 3OVXA 3K8UA 1AIMA 1CPJA 3QT4A 4FIPA 2DC7A 2DCAA 4QRGA 3H7DA 4P6EA 1YT7A 4PP1A 4DMXA 1AU3A 2PREA 1STFE 1THEA 1IWDA 1ITOA 3I3TA 3D6SA 2YJCA 2AYNA 4BS5A 2G8EA 1PPPA 2NQIA 3WXEA 3H6SA 3PDFA 4BS6A 9PAPA 3K9MA 2PBHA 1AECA 3KWZA 2FUDA 1PPOA 3IOQA 1CV8A 1TU6A 2E02A 2ACTA 1F2BA 3H89A 2R9FA 5CVNB 2P0RA 2Y6EA 3F5VA 3C9EA 1GCBA 1MEMA 2AYOA 3BPFA 1YK7A 4YYUA 4QH6A 3IUTA 2FO5A 3IMAA 2E00A 3M99A 3P5VA 2FTDA 1U9XA 3O0UA 5F02A 1Y4HA 4YV8A 3MHSA 3PNRA 3KWBX 2E01A 4CDCB 2R9NA 4BPVA 1AU2A 1MHWA 1JQPA 4CDEB 2IBIA 1KXRA 1MS6A 5A24A 2YJBA 3LFYA 3P5XA 2NQDB 2O6XA 4XUIA 2AUZA 4WA6A 2R9MA 3QJ3A 1S4VA 2H7JA 5EGWA 4MZOA 2VHSA 4CDFB 2XU5A 1BGOA 3CH3X 1KHPA 1CSBB 4AXLA 3N3GA 1O0EA 1QOLA 2DC8A 1POPA 4YYRA 1U9WA 1EWLA 3OF8A 2NQGA 1X9YA 2XU4A 1F29A 2CB5A 1BQIA 2FQ9A 1AU0A 2Y5BA 1GLOA 2AUXA 5CHTA 2AVWA 1NQCA 2HH5A 2CIOA 7PCKA 1BP4A 3B79A 1PADA 1ZIVA 1AYUA 2FYEA 2XU1A 1AYWA 4X6JA 2YJ9A 1EWMA 1CQDA 3OVZA 4FJCA 4HWYA 3KSEA 1PE6A 3N3KA 2F1GA 1NB5A 4YYSA 1KHQA 3IHPA 2IPPB 4ZUXU 3MTNA 3MHHA 5PADA 5CVMA 1EWOA 3LXSA 4KLBA 2PNSA 3E1ZB 2DJFB 1ATKA 1NB3A 2PADA 2G7YA 1TLOA 2WBFX 2F7DA 5K16A 2GHUA 1DF0A 1KFUL 2DZYA 4I07A 2E03A 2OULA 1SNKA 1ICFA 1U5IA 3RVVA 1ZCMA
chains in the Genus database with same CATH superfamily
4I05A 3KW9A 1F2AA 3IEJA 2Z84A 1EWPA 1MDWA 4OELA 3ZUAA 1YALA 5JA7A 4BOSA 2B1MA 2DC6A 5KO3A 4RY2A 3HHAA 4OEMA 3PHWA 2FE8A 5JH3A 2C0YA 2DCDA 3OQCA 1CTEA 3GCBA 1ME3A 1NLJA 4IP3A 4REZA 1QDQA 4W5CA 4Q8HA 1CS8A 4FK5A 3IV2A 1F2CA 4BOPA 3TRKA 4ZTBA 4G54A 3CBKA 2P86A 2NQAA 2ARYA 4A5UA 1SP4B 4QBBA 3PT2A 3I06A 1NL6A 3KFQA 1U9VA 3N4CA 3K24A 1AYVA 2B1NA 3ERVA 2AS8A 3MORA 1FH0A 2FRQA 2HXZA 1PPDA 4BQVA 4XR7A 2OP3A 4W4UA 1YVBA 1K3BB 2DC9A 1XKGA 3W31A 3S3RA 3BC3A 4QRVA 5CHVA 1PPNA 2J7QC 4PI3A 3WXGA 3PBHA 3AI8A 4RNAA 3O1GA 1Y08A 4AXMA 1QXPA 4MZSA 3HD3A 3H8CA 3RVWA 1PIPA 2DJGB 2GFOA 3BB7A 3O65A 3P5UA 4N79A 5EF4A 3RVXA 2G6DA 2XU3A 2BDZA 1MEGA 3WXFA 3B21A 3BY4A 3S3QA 3CBJA 2DCBA 3USVA 4CZWA 2AGAA 8PCHA 1Q6KA 2YJ8A 4QRXA 3MTVA 4X6HA 3OISA 4YYQA 3OF9A 1VJVA 4MSXA 2BDLA 3TMPA 1U9QX 1QMYA 4X6IA 2HWKA 1TL9A 2ATOA 3F75A 4HXDB 4P6GA 1CVZA 2DZZA 3HHIA 4PP2E 2AIMA 1GECE 4PADA 1VSNA 3BPMA 5J94A 1M6DA 5JZEA 4RF1A 3V6EA 4OVZB 1UKFA 3MP2A 1GMYA 3U8EA 4Q8GA 2P7UA 1AU4A 1DEUA 2R9OA 3H8BA 4CDDB 4YYVA 1EF7A 3KX1A 3V6CA 3KKUA 4YYWA 1PBHA 2DCCA 2G8JA 4DMYA 2BTWB 2VHFA 2FT2A 4N8WA 2JQFR 5EZQA 1NPZA 2R9CA 2R6NA 4W5BA 3BOWA 3PRMA 1PCIA 1PXVA 1A6RA 1MIRA 3HWNA 3QSDA 1YK8A 1ME4A 2HD5A 4YVAA 2JQGR 3NHEA 3PW3A 1KFXL 4D8IA 3TNXA 5FPWA 1CB5A 2AU1A 1BY8A 2YJ2A 4BOUA 2FRAA 3BCNA 3DF0A 3P5WA 1CJLA 4BSQA 1HUCB 2OZ2A 2HHNA 3E9SA 5CVOB 4K7CA 3CH2X 6PADA 3BWKA 4I04A 4N4ZA 3OVXA 3K8UA 1AIMA 1CPJA 3QT4A 4OVZA 2DC7A 4FIPA 2DCAA 4QRGA 3H7DA 4P6EA 1YT7A 4PP1A 4DMXA 1AU3A 2PREA 1STFE 1THEA 1IWDA 4BOZA 1ITOA 3I3TA 3D6SA 2YJCA 2AYNA 4BS5A 2G8EA 2BTWA 1PPPA 2NQIA 3WXEA 3H6SA 3PDFA 4BS6A 9PAPA 3K9MA 2PBHA 3PHXA 1AECA 4MM3B 3KWZA 2FUDA 1PPOA 3IOQA 4XZXA 4WURA 1CV8A 1TU6A 4D8EA 2E02A 2ACTA 1F2BA 1YZBA 3H89A 2R9FA 5CVNB 2P0RA 2Y6EA 3F5VA 2DOSA 3C9EA 1GCBA 1MEMA 2AYOA 3BPFA 1YK7A 4YYUA 5E6JA 3ZNHA 4QH6A 3IUTA 2FO5A 3IMAA 2E00A 3M99A 3P5VA 2FTDA 3BBAA 1U9XA 3O0UA 5F02A 1Y4HA 4YV8A 3MHSA 3PNRA 3KWBX 2E01A 4CDCB 3PSEA 2R9NA 4RKXA 4BPVA 1AU2A 1MHWA 1JQPA 4CDEB 2IBIA 1KXRA 1MS6A 5A24A 2YJBA 3MJ5A 3LFYA 3P5XA 2NQDB 2O6XA 4XUIA 2AUZA 2JTCA 3RNVA 4R3DA 4WA6A 2R9MA 4GUAA 3QJ3A 1S4VA 2H7JA 4M0WA 5EGWA 4MZOA 2VHSA 4CDFB 2XU5A 4MI7A 1BGOA 3CH3X 1KHPA 5EZSA 1CSBB 4AXLA 3N3GA 1O0EA 1PVJA 1QOLA 2DC8A 1POPA 4YYRA 1U9WA 1EWLA 3OF8A 2NQGA 1X9YA 2XU4A 1F29A 2CB5A 1BQIA 2FQ9A 1AU0A 2Y5BA 1GLOA 3W30A 4RF0A 2AUXA 5CHTA 2AVWA 1NQCA 2HH5A 2CIOA 3C0RA 7PCKA 4IUMA 1BP4A 3B79A 1PADA 1ZIVA 3PRPA 1AYUA 2FYEA 2XU1A 1AYWA 4PT5A 2BU3A 4X6JA 2YJ9A 4OW0A 1EWMA 1CQDA 3OVZA 4FJCA 4HWYA 3KSEA 4P16A 1PE6A 3N3KA 3IFUA 2F1GA 1NB5A 4YYSA 1KHQA 3IHPA 2IPPB 4ZUXU 3MTNA 3MHHA 5PADA 5CVMA 1EWOA 3LXSA 4KLBA 2PNSA 3E1ZB 1DKIA 2DJFB 4BOQA 1ATKA 1NB3A 2PADA 2G7YA 1TLOA 2WBFX 2F7DA 2J7QA 5K16A 2GHUA 1DF0A 1KFUL 2JRIA 2DZYA 4I07A 2E03A 2OULA 4D8BA 3PHUA 1SNKA 1ICFA 1U5IA 2UZJA 3RVVA 1ZCMA
chains in the Genus database with same CATH topology
4I05A 3KW9A 1F2AA 3IEJA 1EWPA 1MDWA 4OELA 3ZUAA 1YALA 5JA7A 3LTWA 2B1MA 2DC6A 4RY2A 3HHAA 4OEMA 5JH3A 2C0YA 2DCDA 1CTEA 3GCBA 2VFBA 1ME3A 1NLJA 4W5CA 1QDQA 4Q8HA 1CS8A 4FK5A 3IV2A 1F2CA 4G54A 3CBKA 2P86A 2NQAA 2ARYA 1SP4B 4QBBA 3I06A 1NL6A 3KFQA 1U9VA 3N4CA 3K24A 1AYVA 2BSZA 2B1NA 3ERVA 2AS8A 3MORA 1FH0A 2FRQA 2HXZA 4NV7A 1PPDA 4BQVA 4XR7A 1W6FA 2OP3A 4W4UA 1YVBA 1K3BB 2DC9A 1XKGA 3S3RA 3BC3A 4QRVA 5CHVA 1PPNA 4PI3A 3WXGA 3PBHA 3AI8A 3O1GA 1Y08A 4AXMA 1QXPA 4MZSA 3HD3A 3H8CA 3RVWA 1PIPA 2DJGB 2GFOA 3P5UA 4N79A 5EF4A 3RVXA 2G6DA 4BGFA 2XU3A 2BDZA 1MEGA 3WXFA 3S3QA 3CBJA 2DCBA 3USVA 4CZWA 8PCHA 1Q6KA 2YJ8A 4QRXA 4X6HA 3OISA 4YYQA 3OF9A 1VJVA 4MSXA 2BDLA 1U9QX 1QMYA 4X6IA 1TL9A 2ATOA 3F75A 4P6GA 1CVZA 2DZZA 3HHIA 4PP2E 2AIMA 1GECE 4PADA 1VSNA 3BPMA 5J94A 1M6DA 3D9WA 3V6EA 1GMYA 3U8EA 4Q8GA 2P7UA 1AU4A 1DEUA 2R9OA 3H8BA 4CDDB 4YYVA 1EF7A 3KX1A 3V6CA 3KKUA 4YYWA 1PBHA 2DCCA 2G8JA 4DMYA 2VHFA 4N8WA 2FT2A 2JQFR 1NPZA 2R9CA 2R6NA 4W5BA 3BOWA 1PCIA 1PXVA 1A6RA 1MIRA 3HWNA 3QSDA 1YK8A 1ME4A 2HD5A 4YVAA 2JQGR 3NHEA 3PW3A 1KFXL 3TNXA 5FPWA 1CB5A 2AU1A 1BY8A 2YJ2A 2FRAA 3BCNA 4NV8A 3DF0A 3P5WA 1CJLA 4BSQA 1HUCB 4C5PA 2OZ2A 2HHNA 5CVOB 4K7CA 3CH2X 6PADA 3BWKA 4I04A 4N4ZA 3OVXA 3K8UA 1AIMA 1CPJA 3QT4A 4FIPA 2DC7A 2DCAA 4QRGA 3H7DA 4P6EA 1YT7A 4PP1A 4DMXA 1AU3A 2PREA 1STFE 1THEA 1IWDA 1ITOA 3I3TA 3D6SA 2YJCA 2AYNA 4BS5A 2G8EA 1PPPA 2NQIA 3WXEA 3H6SA 3PDFA 4BS6A 9PAPA 4GUZA 3K9MA 2PBHA 1AECA 3KWZA 2FUDA 1PPOA 3IOQA 1CV8A 1TU6A 2E02A 2ACTA 1F2BA 3H89A 2R9FA 1GX3A 5CVNB 2P0RA 2Y6EA 3F5VA 3C9EA 1GCBA 1MEMA 2AYOA 3BPFA 1YK7A 4YYUA 4QH6A 3IUTA 2FO5A 3IMAA 2E00A 3M99A 3P5VA 2FTDA 1U9XA 1W4TA 3O0UA 5F02A 1Y4HA 4YV8A 3MHSA 3PNRA 3KWBX 2E01A 4CDCB 2R9NA 4BPVA 1AU2A 1MHWA 1JQPA 4CDEB 2IBIA 1KXRA 1MS6A 5A24A 2YJBA 3LFYA 3P5XA 2NQDB 2O6XA 4XUIA 2AUZA 4WA6A 2R9MA 3QJ3A 1S4VA 2H7JA 5EGWA 4MZOA 2VHSA 4CDFB 2XU5A 1BGOA 3CH3X 1KHPA 1CSBB 4AXLA 3N3GA 1O0EA 1QOLA 2DC8A 1POPA 4YYRA 1U9WA 1EWLA 3OF8A 2NQGA 1X9YA 2XU4A 1F29A 2CB5A 1BQIA 2FQ9A 1AU0A 2Y5BA 1GLOA 2AUXA 5CHTA 2AVWA 1NQCA 2HH5A 2CIOA 7PCKA 1BP4A 3B79A 1PADA 1ZIVA 1AYUA 2FYEA 2XU1A 1AYWA 4X6JA 2YJ9A 1EWMA 1E2TA 1CQDA 3OVZA 4FJCA 4HWYA 3KSEA 1PE6A 3N3KA 2F1GA 1NB5A 4YYSA 1KHQA 3IHPA 2IPPB 4ZUXU 3MTNA 3MHHA 5PADA 5CVMA 1EWOA 3LXSA 4KLBA 2PNSA 3E1ZB 2DJFB 1ATKA 1NB3A 2PADA 1W5RA 2G7YA 1TLOA 2WBFX 2F7DA 5K16A 2GHUA 4B55A 1DF0A 1KFUL 2VFCA 2DZYA 4I07A 2E03A 2OULA 1SNKA 1ICFA 1U5IA 3RVVA 1ZCMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I05 A;  3KW9 A;  1F2A A;  3IEJ A;  1EWP A;  1MDW A;  4OEL A;  3ZUA A;  1YAL A;  5JA7 A;  2B1M A;  2DC6 A;  4RY2 A;  3HHA A;  4OEM A;  5JH3 A;  2C0Y A;  2DCD A;  1CTE A;  3GCB A;  1ME3 A;  1NLJ A;  4W5C A;  1QDQ A;  4Q8H A;  1CS8 A;  4FK5 A;  3IV2 A;  1F2C A;  4G54 A;  3CBK A;  2P86 A;  2NQA A;  2ARY A;  1SP4 B;  4QBB A;  3I06 A;  1NL6 A;  3KFQ A;  1U9V A;  3N4C A;  3K24 A;  1AYV A;  2B1N A;  3ERV A;  2AS8 A;  3MOR A;  1FH0 A;  2FRQ A;  2HXZ A;  1PPD A;  4BQV A;  4XR7 A;  2OP3 A;  4W4U A;  1YVB A;  1K3B B;  2DC9 A;  1XKG A;  3S3R A;  3BC3 A;  4QRV A;  5CHV A;  1PPN A;  4PI3 A;  3WXG A;  3PBH A;  3AI8 A;  3O1G A;  1Y08 A;  4AXM A;  1QXP A;  4MZS A;  3HD3 A;  3H8C A;  3RVW A;  1PIP A;  2DJG B;  2GFO A;  3P5U A;  4N79 A;  5EF4 A;  3RVX A;  2G6D A;  2XU3 A;  2BDZ A;  1MEG A;  3WXF A;  3S3Q A;  3CBJ A;  2DCB A;  3USV A;  4CZW A;  8PCH A;  1Q6K A;  2YJ8 A;  4QRX A;  4X6H A;  3OIS A;  4YYQ A;  3OF9 A;  1VJV A;  4MSX A;  2BDL A;  1U9Q X;  1QMY A;  4X6I A;  1TL9 A;  2ATO A;  3F75 A;  4P6G A;  1CVZ A;  2DZZ A;  3HHI A;  4PP2 E;  2AIM A;  1GEC E;  4PAD A;  1VSN A;  3BPM A;  5J94 A;  1M6D A;  3V6E A;  1GMY A;  3U8E A;  4Q8G A;  2P7U A;  1AU4 A;  1DEU A;  2R9O A;  3H8B A;  4CDD B;  4YYV A;  1EF7 A;  3KX1 A;  3V6C A;  3KKU A;  4YYW A;  1PBH A;  2DCC A;  2G8J A;  4DMY A;  2VHF A;  2FT2 A;  4N8W A;  2JQF R;  1NPZ A;  2R9C A;  2R6N A;  4W5B A;  3BOW A;  1PCI A;  1PXV A;  1A6R A;  1MIR A;  3HWN A;  3QSD A;  1YK8 A;  1ME4 A;  2HD5 A;  4YVA A;  2JQG R;  3NHE A;  3PW3 A;  1KFX L;  3TNX A;  5FPW A;  1CB5 A;  2AU1 A;  1BY8 A;  2YJ2 A;  2FRA A;  3BCN A;  3DF0 A;  3P5W A;  1CJL A;  4BSQ A;  1HUC B;  2OZ2 A;  2HHN A;  5CVO B;  4K7C A;  3CH2 X;  6PAD A;  3BWK A;  4I04 A;  4N4Z A;  3OVX A;  3K8U A;  1AIM A;  1CPJ A;  3QT4 A;  4FIP A;  2DC7 A;  2DCA A;  4QRG A;  3H7D A;  4P6E A;  1YT7 A;  4PP1 A;  4DMX A;  1AU3 A;  2PRE A;  1STF E;  1THE A;  1IWD A;  1ITO A;  3I3T A;  3D6S A;  2YJC A;  2AYN A;  4BS5 A;  2G8E A;  1PPP A;  2NQI A;  3WXE A;  3H6S A;  3PDF A;  4BS6 A;  9PAP A;  3K9M A;  2PBH A;  1AEC A;  3KWZ A;  2FUD A;  1PPO A;  3IOQ A;  1CV8 A;  1TU6 A;  2E02 A;  2ACT A;  1F2B A;  3H89 A;  2R9F A;  5CVN B;  2P0R A;  2Y6E A;  3F5V A;  3C9E A;  1GCB A;  1MEM A;  2AYO A;  3BPF A;  1YK7 A;  4YYU A;  4QH6 A;  3IUT A;  2FO5 A;  3IMA A;  2E00 A;  3M99 A;  3P5V A;  2FTD A;  1U9X A;  3O0U A;  5F02 A;  1Y4H A;  4YV8 A;  3MHS A;  3PNR A;  3KWB X;  2E01 A;  4CDC B;  2R9N A;  4BPV A;  1AU2 A;  1MHW A;  1JQP A;  4CDE B;  2IBI A;  1KXR A;  1MS6 A;  5A24 A;  2YJB A;  3LFY A;  3P5X A;  2NQD B;  2O6X A;  4XUI A;  2AUZ A;  4WA6 A;  2R9M A;  3QJ3 A;  1S4V A;  2H7J A;  5EGW A;  4MZO A;  2VHS A;  4CDF B;  2XU5 A;  1BGO A;  3CH3 X;  1KHP A;  1CSB B;  4AXL A;  3N3G A;  1O0E A;  1QOL A;  2DC8 A;  1POP A;  4YYR A;  1U9W A;  1EWL A;  3OF8 A;  2NQG A;  1X9Y A;  2XU4 A;  1F29 A;  2CB5 A;  1BQI A;  2FQ9 A;  1AU0 A;  2Y5B A;  1GLO A;  2AUX A;  5CHT A;  2AVW A;  1NQC A;  2HH5 A;  2CIO A;  7PCK A;  1BP4 A;  3B79 A;  1PAD A;  1ZIV A;  1AYU A;  2FYE A;  2XU1 A;  1AYW A;  4X6J A;  2YJ9 A;  1EWM A;  1CQD A;  3OVZ A;  4FJC A;  4HWY A;  3KSE A;  1PE6 A;  3N3K A;  2F1G A;  1NB5 A;  4YYS A;  1KHQ A;  3IHP A;  2IPP B;  4ZUX U;  3MTN A;  3MHH A;  5PAD A;  5CVM A;  1EWO A;  3LXS A;  4KLB A;  2PNS A;  3E1Z B;  2DJF B;  1ATK A;  1NB3 A;  2PAD A;  2G7Y A;  1TLO A;  2WBF X;  2F7D A;  5K16 A;  2GHU A;  1DF0 A;  1KFU L;  2DZY A;  4I07 A;  2E03 A;  2OUL A;  1SNK A;  1ICF A;  1U5I A;  3RVV A;  1ZCM A; 
#chains in the Genus database with same CATH topology
 4I05 A;  3KW9 A;  1F2A A;  3IEJ A;  2Z84 A;  1EWP A;  1MDW A;  4OEL A;  3ZUA A;  1YAL A;  5JA7 A;  4BOS A;  2B1M A;  2DC6 A;  5KO3 A;  4RY2 A;  3HHA A;  4OEM A;  3PHW A;  2FE8 A;  5JH3 A;  2C0Y A;  2DCD A;  3OQC A;  1CTE A;  3GCB A;  1ME3 A;  1NLJ A;  4IP3 A;  4REZ A;  1QDQ A;  4W5C A;  4Q8H A;  1CS8 A;  4FK5 A;  3IV2 A;  1F2C A;  4BOP A;  3TRK A;  4ZTB A;  4G54 A;  3CBK A;  2P86 A;  2NQA A;  2ARY A;  4A5U A;  1SP4 B;  4QBB A;  3PT2 A;  3I06 A;  1NL6 A;  3KFQ A;  1U9V A;  3N4C A;  3K24 A;  1AYV A;  2B1N A;  3ERV A;  2AS8 A;  3MOR A;  1FH0 A;  2FRQ A;  2HXZ A;  1PPD A;  4BQV A;  4XR7 A;  2OP3 A;  4W4U A;  1YVB A;  1K3B B;  2DC9 A;  1XKG A;  3W31 A;  3S3R A;  3BC3 A;  4QRV A;  5CHV A;  1PPN A;  2J7Q C;  4PI3 A;  3WXG A;  3PBH A;  3AI8 A;  4RNA A;  3O1G A;  1Y08 A;  4AXM A;  1QXP A;  4MZS A;  3HD3 A;  3H8C A;  3RVW A;  1PIP A;  2DJG B;  2GFO A;  3BB7 A;  3O65 A;  3P5U A;  4N79 A;  5EF4 A;  3RVX A;  2G6D A;  2XU3 A;  2BDZ A;  1MEG A;  3WXF A;  3B21 A;  3BY4 A;  3S3Q A;  3CBJ A;  2DCB A;  3USV A;  4CZW A;  2AGA A;  8PCH A;  1Q6K A;  2YJ8 A;  4QRX A;  3MTV A;  4X6H A;  3OIS A;  4YYQ A;  3OF9 A;  1VJV A;  4MSX A;  2BDL A;  3TMP A;  1U9Q X;  1QMY A;  4X6I A;  2HWK A;  1TL9 A;  2ATO A;  3F75 A;  4HXD B;  4P6G A;  1CVZ A;  2DZZ A;  3HHI A;  4PP2 E;  2AIM A;  1GEC E;  4PAD A;  1VSN A;  3BPM A;  5J94 A;  1M6D A;  5JZE A;  4RF1 A;  3V6E A;  4OVZ B;  1UKF A;  3MP2 A;  1GMY A;  3U8E A;  4Q8G A;  2P7U A;  1AU4 A;  1DEU A;  2R9O A;  3H8B A;  4CDD B;  4YYV A;  1EF7 A;  3KX1 A;  3V6C A;  3KKU A;  4YYW A;  1PBH A;  2DCC A;  2G8J A;  4DMY A;  2BTW B;  2VHF A;  2FT2 A;  4N8W A;  2JQF R;  5EZQ A;  1NPZ A;  2R9C A;  2R6N A;  4W5B A;  3BOW A;  3PRM A;  1PCI A;  1PXV A;  1A6R A;  1MIR A;  3HWN A;  3QSD A;  1YK8 A;  1ME4 A;  2HD5 A;  4YVA A;  2JQG R;  3NHE A;  3PW3 A;  1KFX L;  4D8I A;  3TNX A;  5FPW A;  1CB5 A;  2AU1 A;  1BY8 A;  2YJ2 A;  4BOU A;  2FRA A;  3BCN A;  3DF0 A;  3P5W A;  1CJL A;  4BSQ A;  1HUC B;  2OZ2 A;  2HHN A;  3E9S A;  5CVO B;  4K7C A;  3CH2 X;  6PAD A;  3BWK A;  4I04 A;  4N4Z A;  3OVX A;  3K8U A;  1AIM A;  1CPJ A;  3QT4 A;  4OVZ A;  2DC7 A;  4FIP A;  2DCA A;  4QRG A;  3H7D A;  4P6E A;  1YT7 A;  4PP1 A;  4DMX A;  1AU3 A;  2PRE A;  1STF E;  1THE A;  1IWD A;  4BOZ A;  1ITO A;  3I3T A;  3D6S A;  2YJC A;  2AYN A;  4BS5 A;  2G8E A;  2BTW A;  1PPP A;  2NQI A;  3WXE A;  3H6S A;  3PDF A;  4BS6 A;  9PAP A;  3K9M A;  2PBH A;  3PHX A;  1AEC A;  4MM3 B;  3KWZ A;  2FUD A;  1PPO A;  3IOQ A;  4XZX A;  4WUR A;  1CV8 A;  1TU6 A;  4D8E A;  2E02 A;  2ACT A;  1F2B A;  1YZB A;  3H89 A;  2R9F A;  5CVN B;  2P0R A;  2Y6E A;  3F5V A;  2DOS A;  3C9E A;  1GCB A;  1MEM A;  2AYO A;  3BPF A;  1YK7 A;  4YYU A;  5E6J A;  3ZNH A;  4QH6 A;  3IUT A;  2FO5 A;  3IMA A;  2E00 A;  3M99 A;  3P5V A;  2FTD A;  3BBA A;  1U9X A;  3O0U A;  5F02 A;  1Y4H A;  4YV8 A;  3MHS A;  3PNR A;  3KWB X;  2E01 A;  4CDC B;  3PSE A;  2R9N A;  4RKX A;  4BPV A;  1AU2 A;  1MHW A;  1JQP A;  4CDE B;  2IBI A;  1KXR A;  1MS6 A;  5A24 A;  2YJB A;  3MJ5 A;  3LFY A;  3P5X A;  2NQD B;  2O6X A;  4XUI A;  2AUZ A;  2JTC A;  3RNV A;  4R3D A;  4WA6 A;  2R9M A;  4GUA A;  3QJ3 A;  1S4V A;  2H7J A;  4M0W A;  5EGW A;  4MZO A;  2VHS A;  4CDF B;  2XU5 A;  4MI7 A;  1BGO A;  3CH3 X;  1KHP A;  5EZS A;  1CSB B;  4AXL A;  3N3G A;  1O0E A;  1PVJ A;  1QOL A;  2DC8 A;  1POP A;  4YYR A;  1U9W A;  1EWL A;  3OF8 A;  2NQG A;  1X9Y A;  2XU4 A;  1F29 A;  2CB5 A;  1BQI A;  2FQ9 A;  1AU0 A;  2Y5B A;  1GLO A;  3W30 A;  4RF0 A;  2AUX A;  5CHT A;  2AVW A;  1NQC A;  2HH5 A;  2CIO A;  3C0R A;  7PCK A;  4IUM A;  1BP4 A;  3B79 A;  1PAD A;  1ZIV A;  3PRP A;  1AYU A;  2FYE A;  2XU1 A;  1AYW A;  4PT5 A;  2BU3 A;  4X6J A;  2YJ9 A;  4OW0 A;  1EWM A;  1CQD A;  3OVZ A;  4FJC A;  4HWY A;  3KSE A;  4P16 A;  1PE6 A;  3N3K A;  3IFU A;  2F1G A;  1NB5 A;  4YYS A;  1KHQ A;  3IHP A;  2IPP B;  4ZUX U;  3MTN A;  3MHH A;  5PAD A;  5CVM A;  1EWO A;  3LXS A;  4KLB A;  2PNS A;  3E1Z B;  1DKI A;  2DJF B;  4BOQ A;  1ATK A;  1NB3 A;  2PAD A;  2G7Y A;  1TLO A;  2WBF X;  2F7D A;  2J7Q A;  5K16 A;  2GHU A;  1DF0 A;  1KFU L;  2JRI A;  2DZY A;  4I07 A;  2E03 A;  2OUL A;  4D8B A;  3PHU A;  1SNK A;  1ICF A;  1U5I A;  2UZJ A;  3RVV A;  1ZCM A; 
#chains in the Genus database with same CATH homology
 4I05 A;  3KW9 A;  1F2A A;  3IEJ A;  1EWP A;  1MDW A;  4OEL A;  3ZUA A;  1YAL A;  5JA7 A;  3LTW A;  2B1M A;  2DC6 A;  4RY2 A;  3HHA A;  4OEM A;  5JH3 A;  2C0Y A;  2DCD A;  1CTE A;  3GCB A;  2VFB A;  1ME3 A;  1NLJ A;  4W5C A;  1QDQ A;  4Q8H A;  1CS8 A;  4FK5 A;  3IV2 A;  1F2C A;  4G54 A;  3CBK A;  2P86 A;  2NQA A;  2ARY A;  1SP4 B;  4QBB A;  3I06 A;  1NL6 A;  3KFQ A;  1U9V A;  3N4C A;  3K24 A;  1AYV A;  2BSZ A;  2B1N A;  3ERV A;  2AS8 A;  3MOR A;  1FH0 A;  2FRQ A;  2HXZ A;  4NV7 A;  1PPD A;  4BQV A;  4XR7 A;  1W6F A;  2OP3 A;  4W4U A;  1YVB A;  1K3B B;  2DC9 A;  1XKG A;  3S3R A;  3BC3 A;  4QRV A;  5CHV A;  1PPN A;  4PI3 A;  3WXG A;  3PBH A;  3AI8 A;  3O1G A;  1Y08 A;  4AXM A;  1QXP A;  4MZS A;  3HD3 A;  3H8C A;  3RVW A;  1PIP A;  2DJG B;  2GFO A;  3P5U A;  4N79 A;  5EF4 A;  3RVX A;  2G6D A;  4BGF A;  2XU3 A;  2BDZ A;  1MEG A;  3WXF A;  3S3Q A;  3CBJ A;  2DCB A;  3USV A;  4CZW A;  8PCH A;  1Q6K A;  2YJ8 A;  4QRX A;  4X6H A;  3OIS A;  4YYQ A;  3OF9 A;  1VJV A;  4MSX A;  2BDL A;  1U9Q X;  1QMY A;  4X6I A;  1TL9 A;  2ATO A;  3F75 A;  4P6G A;  1CVZ A;  2DZZ A;  3HHI A;  4PP2 E;  2AIM A;  1GEC E;  4PAD A;  1VSN A;  3BPM A;  5J94 A;  1M6D A;  3D9W A;  3V6E A;  1GMY A;  3U8E A;  4Q8G A;  2P7U A;  1AU4 A;  1DEU A;  2R9O A;  3H8B A;  4CDD B;  4YYV A;  1EF7 A;  3KX1 A;  3V6C A;  3KKU A;  4YYW A;  1PBH A;  2DCC A;  2G8J A;  4DMY A;  2VHF A;  4N8W A;  2FT2 A;  2JQF R;  1NPZ A;  2R9C A;  2R6N A;  4W5B A;  3BOW A;  1PCI A;  1PXV A;  1A6R A;  1MIR A;  3HWN A;  3QSD A;  1YK8 A;  1ME4 A;  2HD5 A;  4YVA A;  2JQG R;  3NHE A;  3PW3 A;  1KFX L;  3TNX A;  5FPW A;  1CB5 A;  2AU1 A;  1BY8 A;  2YJ2 A;  2FRA A;  3BCN A;  4NV8 A;  3DF0 A;  3P5W A;  1CJL A;  4BSQ A;  1HUC B;  4C5P A;  2OZ2 A;  2HHN A;  5CVO B;  4K7C A;  3CH2 X;  6PAD A;  3BWK A;  4I04 A;  4N4Z A;  3OVX A;  3K8U A;  1AIM A;  1CPJ A;  3QT4 A;  4FIP A;  2DC7 A;  2DCA A;  4QRG A;  3H7D A;  4P6E A;  1YT7 A;  4PP1 A;  4DMX A;  1AU3 A;  2PRE A;  1STF E;  1THE A;  1IWD A;  1ITO A;  3I3T A;  3D6S A;  2YJC A;  2AYN A;  4BS5 A;  2G8E A;  1PPP A;  2NQI A;  3WXE A;  3H6S A;  3PDF A;  4BS6 A;  9PAP A;  4GUZ A;  3K9M A;  2PBH A;  1AEC A;  3KWZ A;  2FUD A;  1PPO A;  3IOQ A;  1CV8 A;  1TU6 A;  2E02 A;  2ACT A;  1F2B A;  3H89 A;  2R9F A;  1GX3 A;  5CVN B;  2P0R A;  2Y6E A;  3F5V A;  3C9E A;  1GCB A;  1MEM A;  2AYO A;  3BPF A;  1YK7 A;  4YYU A;  4QH6 A;  3IUT A;  2FO5 A;  3IMA A;  2E00 A;  3M99 A;  3P5V A;  2FTD A;  1U9X A;  1W4T A;  3O0U A;  5F02 A;  1Y4H A;  4YV8 A;  3MHS A;  3PNR A;  3KWB X;  2E01 A;  4CDC B;  2R9N A;  4BPV A;  1AU2 A;  1MHW A;  1JQP A;  4CDE B;  2IBI A;  1KXR A;  1MS6 A;  5A24 A;  2YJB A;  3LFY A;  3P5X A;  2NQD B;  2O6X A;  4XUI A;  2AUZ A;  4WA6 A;  2R9M A;  3QJ3 A;  1S4V A;  2H7J A;  5EGW A;  4MZO A;  2VHS A;  4CDF B;  2XU5 A;  1BGO A;  3CH3 X;  1KHP A;  1CSB B;  4AXL A;  3N3G A;  1O0E A;  1QOL A;  2DC8 A;  1POP A;  4YYR A;  1U9W A;  1EWL A;  3OF8 A;  2NQG A;  1X9Y A;  2XU4 A;  1F29 A;  2CB5 A;  1BQI A;  2FQ9 A;  1AU0 A;  2Y5B A;  1GLO A;  2AUX A;  5CHT A;  2AVW A;  1NQC A;  2HH5 A;  2CIO A;  7PCK A;  1BP4 A;  3B79 A;  1PAD A;  1ZIV A;  1AYU A;  2FYE A;  2XU1 A;  1AYW A;  4X6J A;  2YJ9 A;  1EWM A;  1E2T A;  1CQD A;  3OVZ A;  4FJC A;  4HWY A;  3KSE A;  1PE6 A;  3N3K A;  2F1G A;  1NB5 A;  4YYS A;  1KHQ A;  3IHP A;  2IPP B;  4ZUX U;  3MTN A;  3MHH A;  5PAD A;  5CVM A;  1EWO A;  3LXS A;  4KLB A;  2PNS A;  3E1Z B;  2DJF B;  1ATK A;  1NB3 A;  2PAD A;  1W5R A;  2G7Y A;  1TLO A;  2WBF X;  2F7D A;  5K16 A;  2GHU A;  4B55 A;  1DF0 A;  1KFU L;  2VFC A;  2DZY A;  4I07 A;  2E03 A;  2OUL A;  1SNK A;  1ICF A;  1U5I A;  3RVV A;  1ZCM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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