1VSNA

Crystal structure of a potent small molecule inhibitor bound to cathepsin k
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
215
structure length
215
Chain Sequence
APDSIDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKATGALLNLAPQNLVDCVSENDGCGGGYMTNAFQYVQRNRGIDSEDAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEAALKRAVAAVGPVSVAIDASLTSFQFYSAGVYYDENCSSDALNHAVLAVGYGIQAGNKHWIIKNSWGESWGNAGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of a potent and selective non-basic cathepsin K inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 62
structure length 215
sequence length 215
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2007-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1vsnA00
1EWLA 3PNRA 4YVAA 1EWPA 2DZZA 2Y6EA 1BP4A 2DCAA 3I3TA 1KFUL 3O0UA 1ITOA 4DMYA 4DMXA 1Q6KA 2DCDA 1CJLA 2C0YA 4X6IA 4KLBA 5CVNB 1NB5A 3LFYA 5JA7A 3O1GA 4PP1A 4AXMA 3OISA 1CS8A 2E00A 2R9MA 2GFOA 1EF7A 1TL9A 3P5WA 1YK8A 2G6DA 2R9NA 3M99A 1EWMA 3BOWA 4BSQA 3QT4A 2YJ2A 2B1NA 2AUXA 2B1MA 3BCNA 3V6EA 1AYVA 1IWDA 1THEA 2XU1A 2ACTA 2YJ8A 5JH3A 1NL6A 1BY8A 2DZYA 2H7JA 3BC3A 4I05A 2AS8A 4YYUA 4YYWA 3IEJA 5EF4A 1MHWA 4I04A 1NQCA 4N4ZA 3PDFA 4FK5A 5CHTA 2CIOA 3H6SA 5CVOB 3RVWA 3P5XA 4P6GA 1S4VA 2DC9A 1YK7A 1NLJA 3CBJA 4FJCA 3CH2X 4CDEB 2HH5A 4CDFB 2G8JA 3QSDA 2IBIA 2AIMA 4N8WA 1PBHA 2DC7A 3USVA 3H89A 3KWZA 1GMYA 4BS5A 4WA6A 3K9MA 1YT7A 1PPPA 4YYQA 4OELA 2JQFR 1MEGA 1ATKA 4W5CA 8PCHA 2P0RA 1FH0A 2NQIA 1GECE 1SNKA 3MHHA 1Y08A 5FPWA 1KHQA 1HUCB 1X9YA 1AU4A 3KW9A 1POPA 2F7DA 4CDDB 3N4CA 4Q8GA 2VHSA 2YJCA 2NQDB 3E1ZB 2CB5A 1CPJA 3LXSA 1DEUA 2R6NA 2O6XA 1AIMA 3F5VA 4BS6A 4P6EA 1MIRA 2AYNA 4PP2E 3RVXA 4ZUXU 4XR7A 2E02A 2BDLA 3BWKA 3V6CA 1YALA 3IMAA 2VHFA 2ARYA 4Q8HA 3K24A 3P5UA 1CTEA 3KKUA 4PI3A 5EGWA 1VSNA 1AU0A 4CDCB 1A6RA 2P7UA 2Y5BA 1PPNA 3PBHA 9PAPA 3H8CA 1MEMA 3MTNA 2E01A 2FT2A 2F1GA 2XU3A 3CBKA 4RY2A 3RVVA 1O0EA 2OULA 1AU3A 5CVMA 3TNXA 3HHAA 2DCCA 4OEMA 1ICFA 3F75A 1F2BA 1XKGA 4YYRA 1BGOA 3NHEA 4FIPA 2AYOA 3B79A 4MZOA 1KHPA 2GHUA 2OP3A 3ERVA 1MS6A 1VJVA 2PADA 3BPMA 1CB5A 3DF0A 4AXLA 3WXFA 1CV8A 4QRGA 3P5VA 3C9EA 2FTDA 2FO5A 3MORA 5J94A 3IUTA 4MSXA 1M6DA 1F2AA 2PNSA 1MDWA 1ME3A 1STFE 2AU1A 3KX1A 3BPFA 4YYVA 1KFXL 1F29A 3OF8A 1TU6A 3PW3A 3AI8A 2PBHA 3MHSA 1U9VA 4PADA 2BDZA 2FUDA 4YYSA 4MZSA 4QRXA 3H7DA 1PPDA 3IV2A 5F02A 2P86A 2HD5A 3D6SA 2R9CA 2DJGB 1ZIVA 1NB3A 4BQVA 4W5BA 2DC6A 2G7YA 4X6HA 2R9FA 3GCBA 1JQPA 3HD3A 2NQGA 4QRVA 4X6JA 2ATOA 4K7CA 2PREA 3OVXA 1ME4A 1BQIA 3ZUAA 1QDQA 2FRAA 4HWYA 1PADA 3HWNA 3I06A 4BPVA 1AU2A 1GCBA 2IPPB 2YJBA 3IHPA 1U9XA 2AUZA 2XU5A 3N3KA 2HXZA 1GLOA 1U5IA 1NPZA 2R9OA 3H8BA 3U8EA 1QOLA 6PADA 4W4UA 4N79A 3OVZA 5PADA 1QMYA 1TLOA 2OZ2A 4XUIA 4G54A 2DCBA 3OF9A 1AYUA 2NQAA 1CSBB 2YJ9A 1PXVA 5A24A 1DF0A 2XU4A 2JQGR 3KFQA 1F2CA 2E03A 4QBBA 1U9WA 2DJFB 2DC8A 1PE6A 1EWOA 3K8UA 3S3QA 2AVWA 2FQ9A 4YV8A 2WBFX 3QJ3A 5CHVA 1SP4B 1PIPA 2FRQA 1QXPA 1U9QX 3WXEA 1YVBA 1PCIA 4CZWA 1CVZA 4QH6A 2HHNA 1Y4HA 3CH3X 3KSEA 7PCKA 5K16A 1ZCMA 1CQDA 1AECA 4I07A 3IOQA 3HHIA 1PPOA 3WXGA 1KXRA 3S3RA 2FYEA 3KWBX 1K3BB 1AYWA 3N3GA 2G8EA
chains in the Genus database with same CATH superfamily
1EWLA 3PNRA 4OW0A 4YVAA 1EWPA 2DZZA 2Y6EA 1BP4A 2DCAA 3I3TA 1KFUL 3O0UA 4MM3B 4XZXA 1ITOA 4DMYA 4DMXA 1Q6KA 2DCDA 1CJLA 2C0YA 4X6IA 4KLBA 2BTWB 4BOUA 5CVNB 1NB5A 3LFYA 3PSEA 4A5UA 3MJ5A 3O1GA 5JA7A 3PHWA 4PP1A 4AXMA 3OISA 1CS8A 2E00A 2R9MA 2GFOA 1EF7A 1TL9A 5EZQA 3P5WA 1YK8A 2G6DA 2R9NA 3M99A 1EWMA 3BOWA 4BSQA 4RF0A 3QT4A 3TMPA 2YJ2A 2B1NA 2AUXA 2B1MA 3BCNA 3V6EA 1AYVA 3O65A 1IWDA 1THEA 2XU1A 4HXDB 2ACTA 2YJ8A 5JH3A 1NL6A 1BY8A 2DZYA 2H7JA 3BC3A 4I05A 2AS8A 4YYUA 4YYWA 3IEJA 5EF4A 1MHWA 4I04A 3BBAA 1NQCA 4OVZB 3E9SA 4N4ZA 3PDFA 4FK5A 5CHTA 2CIOA 3H6SA 5CVOB 3RVWA 2Z84A 3P5XA 4P6GA 1S4VA 2HWKA 2DC9A 4RF1A 1YK7A 1NLJA 3CBJA 4FJCA 3CH2X 4CDEB 2HH5A 3MP2A 4CDFB 2G8JA 3QSDA 2IBIA 2JRIA 2AIMA 4N8WA 1PBHA 2DC7A 3USVA 3H89A 4IP3A 1DKIA 3KWZA 1GMYA 4BS5A 4WA6A 3RNVA 5JZEA 3K9MA 1YT7A 4D8IA 4BOPA 1PPPA 4YYQA 4OELA 4WURA 2JQFR 3OQCA 1MEGA 2J7QC 1ATKA 4W5CA 8PCHA 2P0RA 1FH0A 2NQIA 1GECE 1SNKA 3MHHA 1Y08A 1YZBA 5E6JA 5FPWA 4P16A 1KHQA 1HUCB 1X9YA 1AU4A 3KW9A 1POPA 2F7DA 3W31A 4CDDB 3N4CA 4Q8GA 2VHSA 2YJCA 2NQDB 3E1ZB 2CB5A 1CPJA 3PHXA 3LXSA 1DEUA 2R6NA 2O6XA 1AIMA 3F5VA 2DOSA 4BS6A 4P6EA 1MIRA 4BOSA 2AYNA 4PP2E 3RVXA 4ZUXU 4XR7A 1UKFA 2E02A 2BDLA 3BWKA 3V6CA 1YALA 3IMAA 2VHFA 2ARYA 4Q8HA 3K24A 3P5UA 1CTEA 3KKUA 4PI3A 5EGWA 2J7QA 1VSNA 1AU0A 4CDCB 1A6RA 2P7UA 2Y5BA 1PPNA 3PBHA 9PAPA 3H8CA 1MEMA 3MTNA 2FE8A 2E01A 4RKXA 2FT2A 2F1GA 2XU3A 3CBKA 4RY2A 3RVVA 1O0EA 2OULA 4D8BA 1AU3A 5CVMA 3TNXA 3HHAA 2DCCA 4OEMA 1ICFA 3BY4A 3F75A 4R3DA 3W30A 1F2BA 1XKGA 4YYRA 1BGOA 3NHEA 4FIPA 2AYOA 3B79A 4MZOA 1KHPA 2GHUA 2OP3A 3ERVA 1MS6A 1VJVA 2PADA 3BPMA 1CB5A 3DF0A 4AXLA 3WXFA 1CV8A 4QRGA 3P5VA 3C9EA 2FTDA 2FO5A 3MORA 5J94A 3IUTA 4MSXA 1M6DA 1F2AA 2PNSA 1MDWA 1ME3A 1STFE 2AU1A 3KX1A 3BPFA 4YYVA 2BTWA 1KFXL 1F29A 3OF8A 1TU6A 3PW3A 3AI8A 2PBHA 3MHSA 1U9VA 4PADA 2BDZA 2FUDA 4YYSA 1PVJA 4MZSA 4QRXA 3H7DA 1PPDA 3IV2A 5F02A 4IUMA 2P86A 2HD5A 3D6SA 2R9CA 2DJGB 3B21A 1ZIVA 1NB3A 3MTVA 4BQVA 4W5BA 2DC6A 2G7YA 4X6HA 2R9FA 3GCBA 1JQPA 3HD3A 2NQGA 4QRVA 4X6JA 2ATOA 4K7CA 2PREA 3OVXA 1ME4A 1BQIA 3ZUAA 1QDQA 2FRAA 4HWYA 1PADA 2JTCA 3HWNA 3I06A 4BPVA 4OVZA 1AU2A 1GCBA 2IPPB 2YJBA 3IHPA 1U9XA 2AUZA 2XU5A 3N3KA 4BOZA 2HXZA 4MI7A 1GLOA 3IFUA 1U5IA 1NPZA 2R9OA 3H8BA 3U8EA 3ZNHA 3PRPA 2BU3A 1QOLA 6PADA 4W4UA 4N79A 3TRKA 3OVZA 5PADA 1QMYA 4REZA 1TLOA 2OZ2A 4XUIA 4G54A 3C0RA 2DCBA 3OF9A 1AYUA 2NQAA 1CSBB 3PHUA 2YJ9A 1PXVA 5A24A 1DF0A 2XU4A 2JQGR 5EZSA 3KFQA 1F2CA 2E03A 4QBBA 1U9WA 2DJFB 2DC8A 1PE6A 4PT5A 1EWOA 3K8UA 3S3QA 2AVWA 2FQ9A 4YV8A 2WBFX 4RNAA 3QJ3A 5CHVA 1SP4B 4BOQA 1PIPA 4D8EA 2FRQA 1QXPA 1U9QX 3WXEA 1YVBA 5KO3A 1PCIA 4CZWA 4M0WA 1CVZA 3PT2A 4QH6A 2HHNA 4ZTBA 1Y4HA 3PRMA 3CH3X 3KSEA 7PCKA 5K16A 1ZCMA 2AGAA 1CQDA 1AECA 4I07A 4GUAA 3IOQA 3HHIA 1PPOA 3WXGA 2UZJA 1KXRA 3S3RA 2FYEA 3KWBX 1K3BB 1AYWA 3N3GA 3BB7A 2G8EA
chains in the Genus database with same CATH topology
1EWLA 3PNRA 4YVAA 1EWPA 2DZZA 2Y6EA 1BP4A 2DCAA 3I3TA 1KFUL 3O0UA 1ITOA 4DMYA 4DMXA 1Q6KA 2DCDA 1CJLA 2C0YA 4X6IA 4KLBA 5CVNB 1NB5A 3LFYA 5JA7A 3O1GA 4PP1A 4AXMA 3LTWA 3OISA 1CS8A 2E00A 2R9MA 2GFOA 1EF7A 1TL9A 3P5WA 1YK8A 2G6DA 2R9NA 3M99A 1EWMA 3BOWA 4BSQA 3QT4A 2YJ2A 2B1NA 2AUXA 2B1MA 3BCNA 3V6EA 1AYVA 4B55A 2VFBA 1IWDA 1THEA 2XU1A 2ACTA 2YJ8A 5JH3A 1NL6A 1BY8A 2DZYA 2H7JA 3BC3A 4I05A 2AS8A 4YYUA 4YYWA 3IEJA 5EF4A 1MHWA 4I04A 1NQCA 4N4ZA 3PDFA 4FK5A 5CHTA 2CIOA 3H6SA 5CVOB 3RVWA 3P5XA 4P6GA 1S4VA 2DC9A 1YK7A 1NLJA 3CBJA 4FJCA 3CH2X 4CDEB 2HH5A 1W5RA 4CDFB 2G8JA 3QSDA 2IBIA 4C5PA 2AIMA 4N8WA 1PBHA 2DC7A 3USVA 2BSZA 3H89A 3KWZA 1GMYA 4BS5A 4WA6A 3K9MA 1YT7A 1PPPA 4YYQA 4OELA 2JQFR 1MEGA 1ATKA 4W5CA 8PCHA 2P0RA 1FH0A 2NQIA 1GECE 1SNKA 3MHHA 1Y08A 4BGFA 5FPWA 1KHQA 1HUCB 1X9YA 1AU4A 3KW9A 1POPA 2F7DA 4CDDB 3N4CA 4Q8GA 2VHSA 2YJCA 2NQDB 3E1ZB 2CB5A 1CPJA 3LXSA 1DEUA 2R6NA 2O6XA 1AIMA 3F5VA 4GUZA 4BS6A 4P6EA 1MIRA 2AYNA 4PP2E 3RVXA 4ZUXU 4XR7A 2E02A 2BDLA 3BWKA 3V6CA 1YALA 3IMAA 2VHFA 2ARYA 4Q8HA 3K24A 3P5UA 1CTEA 3KKUA 4PI3A 5EGWA 1VSNA 1AU0A 4CDCB 1A6RA 2P7UA 2Y5BA 1PPNA 3PBHA 9PAPA 3H8CA 1MEMA 3MTNA 2E01A 2FT2A 2F1GA 2XU3A 3CBKA 4RY2A 3RVVA 1O0EA 2OULA 1AU3A 5CVMA 3TNXA 3HHAA 2DCCA 1W4TA 1ICFA 4OEMA 3F75A 1F2BA 1XKGA 4YYRA 1BGOA 3NHEA 4FIPA 2AYOA 3B79A 4MZOA 2VFCA 1KHPA 2GHUA 2OP3A 3ERVA 1MS6A 1VJVA 2PADA 3BPMA 1CB5A 3D9WA 3DF0A 4AXLA 3WXFA 1CV8A 4QRGA 3P5VA 3C9EA 2FTDA 2FO5A 3MORA 5J94A 3IUTA 4MSXA 1M6DA 1F2AA 2PNSA 1MDWA 1ME3A 1STFE 2AU1A 3KX1A 3BPFA 4NV8A 4YYVA 1KFXL 1F29A 3OF8A 1TU6A 3PW3A 3AI8A 2PBHA 3MHSA 1U9VA 4PADA 2BDZA 2FUDA 4YYSA 4MZSA 4QRXA 3H7DA 1PPDA 3IV2A 5F02A 2P86A 2HD5A 3D6SA 2R9CA 2DJGB 1ZIVA 1NB3A 4BQVA 4W5BA 2DC6A 2G7YA 4X6HA 2R9FA 3GCBA 1JQPA 3HD3A 2NQGA 4QRVA 4X6JA 2ATOA 4K7CA 2PREA 3OVXA 1ME4A 1BQIA 3ZUAA 1QDQA 1W6FA 2FRAA 4HWYA 1PADA 3HWNA 3I06A 4BPVA 1AU2A 1GCBA 2IPPB 2YJBA 3IHPA 1U9XA 2AUZA 2XU5A 3N3KA 2HXZA 1GLOA 1U5IA 1NPZA 2R9OA 3H8BA 3U8EA 1QOLA 6PADA 4W4UA 4N79A 3OVZA 5PADA 1QMYA 1TLOA 2OZ2A 4XUIA 4G54A 2DCBA 3OF9A 1AYUA 2NQAA 1CSBB 2YJ9A 1PXVA 5A24A 1DF0A 1E2TA 2XU4A 2JQGR 3KFQA 1F2CA 2E03A 4QBBA 1U9WA 1GX3A 2DC8A 2DJFB 1PE6A 1EWOA 3K8UA 3S3QA 2AVWA 4NV7A 2FQ9A 4YV8A 2WBFX 3QJ3A 5CHVA 1SP4B 1PIPA 2FRQA 1QXPA 1U9QX 3WXEA 1YVBA 1PCIA 4CZWA 1CVZA 4QH6A 2HHNA 1Y4HA 3CH3X 3KSEA 7PCKA 5K16A 1ZCMA 1CQDA 1AECA 4I07A 3IOQA 3HHIA 1PPOA 3WXGA 1KXRA 3S3RA 2FYEA 3KWBX 1K3BB 1AYWA 3N3GA 2G8EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EWL A;  3PNR A;  4YVA A;  1EWP A;  2DZZ A;  2Y6E A;  1BP4 A;  2DCA A;  3I3T A;  1KFU L;  3O0U A;  1ITO A;  4DMY A;  4DMX A;  1Q6K A;  2DCD A;  1CJL A;  2C0Y A;  4X6I A;  4KLB A;  5CVN B;  1NB5 A;  3LFY A;  5JA7 A;  3O1G A;  4PP1 A;  4AXM A;  3OIS A;  1CS8 A;  2E00 A;  2R9M A;  2GFO A;  1EF7 A;  1TL9 A;  3P5W A;  1YK8 A;  2G6D A;  2R9N A;  3M99 A;  1EWM A;  3BOW A;  4BSQ A;  3QT4 A;  2YJ2 A;  2B1N A;  2AUX A;  2B1M A;  3BCN A;  3V6E A;  1AYV A;  1IWD A;  1THE A;  2XU1 A;  2ACT A;  2YJ8 A;  5JH3 A;  1NL6 A;  1BY8 A;  2DZY A;  2H7J A;  3BC3 A;  4I05 A;  2AS8 A;  4YYU A;  4YYW A;  3IEJ A;  5EF4 A;  1MHW A;  4I04 A;  1NQC A;  4N4Z A;  3PDF A;  4FK5 A;  5CHT A;  2CIO A;  3H6S A;  5CVO B;  3RVW A;  3P5X A;  4P6G A;  1S4V A;  2DC9 A;  1YK7 A;  1NLJ A;  3CBJ A;  4FJC A;  3CH2 X;  4CDE B;  2HH5 A;  4CDF B;  2G8J A;  3QSD A;  2IBI A;  2AIM A;  4N8W A;  1PBH A;  2DC7 A;  3USV A;  3H89 A;  3KWZ A;  1GMY A;  4BS5 A;  4WA6 A;  3K9M A;  1YT7 A;  1PPP A;  4YYQ A;  4OEL A;  2JQF R;  1MEG A;  1ATK A;  4W5C A;  8PCH A;  2P0R A;  1FH0 A;  2NQI A;  1GEC E;  1SNK A;  3MHH A;  1Y08 A;  5FPW A;  1KHQ A;  1HUC B;  1X9Y A;  1AU4 A;  3KW9 A;  1POP A;  2F7D A;  4CDD B;  3N4C A;  4Q8G A;  2VHS A;  2YJC A;  2NQD B;  3E1Z B;  2CB5 A;  1CPJ A;  3LXS A;  1DEU A;  2R6N A;  2O6X A;  1AIM A;  3F5V A;  4BS6 A;  4P6E A;  1MIR A;  2AYN A;  4PP2 E;  3RVX A;  4ZUX U;  4XR7 A;  2E02 A;  2BDL A;  3BWK A;  3V6C A;  1YAL A;  3IMA A;  2VHF A;  2ARY A;  4Q8H A;  3K24 A;  3P5U A;  1CTE A;  3KKU A;  4PI3 A;  5EGW A;  1VSN A;  1AU0 A;  4CDC B;  1A6R A;  2P7U A;  2Y5B A;  1PPN A;  3PBH A;  9PAP A;  3H8C A;  1MEM A;  3MTN A;  2E01 A;  2FT2 A;  2F1G A;  2XU3 A;  3CBK A;  4RY2 A;  3RVV A;  1O0E A;  2OUL A;  1AU3 A;  5CVM A;  3TNX A;  3HHA A;  2DCC A;  4OEM A;  1ICF A;  3F75 A;  1F2B A;  1XKG A;  4YYR A;  1BGO A;  3NHE A;  4FIP A;  2AYO A;  3B79 A;  4MZO A;  1KHP A;  2GHU A;  2OP3 A;  3ERV A;  1MS6 A;  1VJV A;  2PAD A;  3BPM A;  1CB5 A;  3DF0 A;  4AXL A;  3WXF A;  1CV8 A;  4QRG A;  3P5V A;  3C9E A;  2FTD A;  2FO5 A;  3MOR A;  5J94 A;  3IUT A;  4MSX A;  1M6D A;  1F2A A;  2PNS A;  1MDW A;  1ME3 A;  1STF E;  2AU1 A;  3KX1 A;  3BPF A;  4YYV A;  1KFX L;  1F29 A;  3OF8 A;  1TU6 A;  3PW3 A;  3AI8 A;  2PBH A;  3MHS A;  1U9V A;  4PAD A;  2BDZ A;  2FUD A;  4YYS A;  4MZS A;  4QRX A;  3H7D A;  1PPD A;  3IV2 A;  5F02 A;  2P86 A;  2HD5 A;  3D6S A;  2R9C A;  2DJG B;  1ZIV A;  1NB3 A;  4BQV A;  4W5B A;  2DC6 A;  2G7Y A;  4X6H A;  2R9F A;  3GCB A;  1JQP A;  3HD3 A;  2NQG A;  4QRV A;  4X6J A;  2ATO A;  4K7C A;  2PRE A;  3OVX A;  1ME4 A;  1BQI A;  3ZUA A;  1QDQ A;  2FRA A;  4HWY A;  1PAD A;  3HWN A;  3I06 A;  4BPV A;  1AU2 A;  1GCB A;  2IPP B;  2YJB A;  3IHP A;  1U9X A;  2AUZ A;  2XU5 A;  3N3K A;  2HXZ A;  1GLO A;  1U5I A;  1NPZ A;  2R9O A;  3H8B A;  3U8E A;  1QOL A;  6PAD A;  4W4U A;  4N79 A;  3OVZ A;  5PAD A;  1QMY A;  1TLO A;  2OZ2 A;  4XUI A;  4G54 A;  2DCB A;  3OF9 A;  1AYU A;  2NQA A;  1CSB B;  2YJ9 A;  1PXV A;  5A24 A;  1DF0 A;  2XU4 A;  2JQG R;  3KFQ A;  1F2C A;  2E03 A;  4QBB A;  1U9W A;  2DJF B;  2DC8 A;  1PE6 A;  1EWO A;  3K8U A;  3S3Q A;  2AVW A;  2FQ9 A;  4YV8 A;  2WBF X;  3QJ3 A;  5CHV A;  1SP4 B;  1PIP A;  2FRQ A;  1QXP A;  1U9Q X;  3WXE A;  1YVB A;  1PCI A;  4CZW A;  1CVZ A;  4QH6 A;  2HHN A;  1Y4H A;  3CH3 X;  3KSE A;  7PCK A;  5K16 A;  1ZCM A;  1CQD A;  1AEC A;  4I07 A;  3IOQ A;  3HHI A;  1PPO A;  3WXG A;  1KXR A;  3S3R A;  2FYE A;  3KWB X;  1K3B B;  1AYW A;  3N3G A;  2G8E A; 
#chains in the Genus database with same CATH topology
 1EWL A;  3PNR A;  4OW0 A;  4YVA A;  1EWP A;  2DZZ A;  2Y6E A;  1BP4 A;  2DCA A;  3I3T A;  1KFU L;  3O0U A;  4MM3 B;  4XZX A;  1ITO A;  4DMY A;  4DMX A;  1Q6K A;  2DCD A;  1CJL A;  2C0Y A;  4X6I A;  4KLB A;  2BTW B;  4BOU A;  5CVN B;  1NB5 A;  3LFY A;  3PSE A;  4A5U A;  3MJ5 A;  3O1G A;  5JA7 A;  3PHW A;  4PP1 A;  4AXM A;  3OIS A;  1CS8 A;  2E00 A;  2R9M A;  2GFO A;  1EF7 A;  1TL9 A;  5EZQ A;  3P5W A;  1YK8 A;  2G6D A;  2R9N A;  3M99 A;  1EWM A;  3BOW A;  4BSQ A;  4RF0 A;  3QT4 A;  3TMP A;  2YJ2 A;  2B1N A;  2AUX A;  2B1M A;  3BCN A;  3V6E A;  1AYV A;  3O65 A;  1IWD A;  1THE A;  2XU1 A;  4HXD B;  2ACT A;  2YJ8 A;  5JH3 A;  1NL6 A;  1BY8 A;  2DZY A;  2H7J A;  3BC3 A;  4I05 A;  2AS8 A;  4YYU A;  4YYW A;  3IEJ A;  5EF4 A;  1MHW A;  4I04 A;  3BBA A;  1NQC A;  4OVZ B;  3E9S A;  4N4Z A;  3PDF A;  4FK5 A;  5CHT A;  2CIO A;  3H6S A;  5CVO B;  3RVW A;  2Z84 A;  3P5X A;  4P6G A;  1S4V A;  2HWK A;  2DC9 A;  4RF1 A;  1YK7 A;  1NLJ A;  3CBJ A;  4FJC A;  3CH2 X;  4CDE B;  2HH5 A;  3MP2 A;  4CDF B;  2G8J A;  3QSD A;  2IBI A;  2JRI A;  2AIM A;  4N8W A;  1PBH A;  2DC7 A;  3USV A;  3H89 A;  4IP3 A;  1DKI A;  3KWZ A;  1GMY A;  4BS5 A;  4WA6 A;  3RNV A;  5JZE A;  3K9M A;  1YT7 A;  4D8I A;  4BOP A;  1PPP A;  4YYQ A;  4OEL A;  4WUR A;  2JQF R;  3OQC A;  1MEG A;  2J7Q C;  1ATK A;  4W5C A;  8PCH A;  2P0R A;  1FH0 A;  2NQI A;  1GEC E;  1SNK A;  3MHH A;  1Y08 A;  1YZB A;  5E6J A;  5FPW A;  4P16 A;  1KHQ A;  1HUC B;  1X9Y A;  1AU4 A;  3KW9 A;  1POP A;  2F7D A;  3W31 A;  4CDD B;  3N4C A;  4Q8G A;  2VHS A;  2YJC A;  2NQD B;  3E1Z B;  2CB5 A;  1CPJ A;  3PHX A;  3LXS A;  1DEU A;  2R6N A;  2O6X A;  1AIM A;  3F5V A;  2DOS A;  4BS6 A;  4P6E A;  1MIR A;  4BOS A;  2AYN A;  4PP2 E;  3RVX A;  4ZUX U;  4XR7 A;  1UKF A;  2E02 A;  2BDL A;  3BWK A;  3V6C A;  1YAL A;  3IMA A;  2VHF A;  2ARY A;  4Q8H A;  3K24 A;  3P5U A;  1CTE A;  3KKU A;  4PI3 A;  5EGW A;  2J7Q A;  1VSN A;  1AU0 A;  4CDC B;  1A6R A;  2P7U A;  2Y5B A;  1PPN A;  3PBH A;  9PAP A;  3H8C A;  1MEM A;  3MTN A;  2FE8 A;  2E01 A;  4RKX A;  2FT2 A;  2F1G A;  2XU3 A;  3CBK A;  4RY2 A;  3RVV A;  1O0E A;  2OUL A;  4D8B A;  1AU3 A;  5CVM A;  3TNX A;  3HHA A;  2DCC A;  4OEM A;  1ICF A;  3BY4 A;  3F75 A;  4R3D A;  3W30 A;  1F2B A;  1XKG A;  4YYR A;  1BGO A;  3NHE A;  4FIP A;  2AYO A;  3B79 A;  4MZO A;  1KHP A;  2GHU A;  2OP3 A;  3ERV A;  1MS6 A;  1VJV A;  2PAD A;  3BPM A;  1CB5 A;  3DF0 A;  4AXL A;  3WXF A;  1CV8 A;  4QRG A;  3P5V A;  3C9E A;  2FTD A;  2FO5 A;  3MOR A;  5J94 A;  3IUT A;  4MSX A;  1M6D A;  1F2A A;  2PNS A;  1MDW A;  1ME3 A;  1STF E;  2AU1 A;  3KX1 A;  3BPF A;  4YYV A;  2BTW A;  1KFX L;  1F29 A;  3OF8 A;  1TU6 A;  3PW3 A;  3AI8 A;  2PBH A;  3MHS A;  1U9V A;  4PAD A;  2BDZ A;  2FUD A;  4YYS A;  1PVJ A;  4MZS A;  4QRX A;  3H7D A;  1PPD A;  3IV2 A;  5F02 A;  4IUM A;  2P86 A;  2HD5 A;  3D6S A;  2R9C A;  2DJG B;  3B21 A;  1ZIV A;  1NB3 A;  3MTV A;  4BQV A;  4W5B A;  2DC6 A;  2G7Y A;  4X6H A;  2R9F A;  3GCB A;  1JQP A;  3HD3 A;  2NQG A;  4QRV A;  4X6J A;  2ATO A;  4K7C A;  2PRE A;  3OVX A;  1ME4 A;  1BQI A;  3ZUA A;  1QDQ A;  2FRA A;  4HWY A;  1PAD A;  2JTC A;  3HWN A;  3I06 A;  4BPV A;  4OVZ A;  1AU2 A;  1GCB A;  2IPP B;  2YJB A;  3IHP A;  1U9X A;  2AUZ A;  2XU5 A;  3N3K A;  4BOZ A;  2HXZ A;  4MI7 A;  1GLO A;  3IFU A;  1U5I A;  1NPZ A;  2R9O A;  3H8B A;  3U8E A;  3ZNH A;  3PRP A;  2BU3 A;  1QOL A;  6PAD A;  4W4U A;  4N79 A;  3TRK A;  3OVZ A;  5PAD A;  1QMY A;  4REZ A;  1TLO A;  2OZ2 A;  4XUI A;  4G54 A;  3C0R A;  2DCB A;  3OF9 A;  1AYU A;  2NQA A;  1CSB B;  3PHU A;  2YJ9 A;  1PXV A;  5A24 A;  1DF0 A;  2XU4 A;  2JQG R;  5EZS A;  3KFQ A;  1F2C A;  2E03 A;  4QBB A;  1U9W A;  2DJF B;  2DC8 A;  1PE6 A;  4PT5 A;  1EWO A;  3K8U A;  3S3Q A;  2AVW A;  2FQ9 A;  4YV8 A;  2WBF X;  4RNA A;  3QJ3 A;  5CHV A;  1SP4 B;  4BOQ A;  1PIP A;  4D8E A;  2FRQ A;  1QXP A;  1U9Q X;  3WXE A;  1YVB A;  5KO3 A;  1PCI A;  4CZW A;  4M0W A;  1CVZ A;  3PT2 A;  4QH6 A;  2HHN A;  4ZTB A;  1Y4H A;  3PRM A;  3CH3 X;  3KSE A;  7PCK A;  5K16 A;  1ZCM A;  2AGA A;  1CQD A;  1AEC A;  4I07 A;  4GUA A;  3IOQ A;  3HHI A;  1PPO A;  3WXG A;  2UZJ A;  1KXR A;  3S3R A;  2FYE A;  3KWB X;  1K3B B;  1AYW A;  3N3G A;  3BB7 A;  2G8E A; 
#chains in the Genus database with same CATH homology
 1EWL A;  3PNR A;  4YVA A;  1EWP A;  2DZZ A;  2Y6E A;  1BP4 A;  2DCA A;  3I3T A;  1KFU L;  3O0U A;  1ITO A;  4DMY A;  4DMX A;  1Q6K A;  2DCD A;  1CJL A;  2C0Y A;  4X6I A;  4KLB A;  5CVN B;  1NB5 A;  3LFY A;  5JA7 A;  3O1G A;  4PP1 A;  4AXM A;  3LTW A;  3OIS A;  1CS8 A;  2E00 A;  2R9M A;  2GFO A;  1EF7 A;  1TL9 A;  3P5W A;  1YK8 A;  2G6D A;  2R9N A;  3M99 A;  1EWM A;  3BOW A;  4BSQ A;  3QT4 A;  2YJ2 A;  2B1N A;  2AUX A;  2B1M A;  3BCN A;  3V6E A;  1AYV A;  4B55 A;  2VFB A;  1IWD A;  1THE A;  2XU1 A;  2ACT A;  2YJ8 A;  5JH3 A;  1NL6 A;  1BY8 A;  2DZY A;  2H7J A;  3BC3 A;  4I05 A;  2AS8 A;  4YYU A;  4YYW A;  3IEJ A;  5EF4 A;  1MHW A;  4I04 A;  1NQC A;  4N4Z A;  3PDF A;  4FK5 A;  5CHT A;  2CIO A;  3H6S A;  5CVO B;  3RVW A;  3P5X A;  4P6G A;  1S4V A;  2DC9 A;  1YK7 A;  1NLJ A;  3CBJ A;  4FJC A;  3CH2 X;  4CDE B;  2HH5 A;  1W5R A;  4CDF B;  2G8J A;  3QSD A;  2IBI A;  4C5P A;  2AIM A;  4N8W A;  1PBH A;  2DC7 A;  3USV A;  2BSZ A;  3H89 A;  3KWZ A;  1GMY A;  4BS5 A;  4WA6 A;  3K9M A;  1YT7 A;  1PPP A;  4YYQ A;  4OEL A;  2JQF R;  1MEG A;  1ATK A;  4W5C A;  8PCH A;  2P0R A;  1FH0 A;  2NQI A;  1GEC E;  1SNK A;  3MHH A;  1Y08 A;  4BGF A;  5FPW A;  1KHQ A;  1HUC B;  1X9Y A;  1AU4 A;  3KW9 A;  1POP A;  2F7D A;  4CDD B;  3N4C A;  4Q8G A;  2VHS A;  2YJC A;  2NQD B;  3E1Z B;  2CB5 A;  1CPJ A;  3LXS A;  1DEU A;  2R6N A;  2O6X A;  1AIM A;  3F5V A;  4GUZ A;  4BS6 A;  4P6E A;  1MIR A;  2AYN A;  4PP2 E;  3RVX A;  4ZUX U;  4XR7 A;  2E02 A;  2BDL A;  3BWK A;  3V6C A;  1YAL A;  3IMA A;  2VHF A;  2ARY A;  4Q8H A;  3K24 A;  3P5U A;  1CTE A;  3KKU A;  4PI3 A;  5EGW A;  1VSN A;  1AU0 A;  4CDC B;  1A6R A;  2P7U A;  2Y5B A;  1PPN A;  3PBH A;  9PAP A;  3H8C A;  1MEM A;  3MTN A;  2E01 A;  2FT2 A;  2F1G A;  2XU3 A;  3CBK A;  4RY2 A;  3RVV A;  1O0E A;  2OUL A;  1AU3 A;  5CVM A;  3TNX A;  3HHA A;  2DCC A;  1W4T A;  1ICF A;  4OEM A;  3F75 A;  1F2B A;  1XKG A;  4YYR A;  1BGO A;  3NHE A;  4FIP A;  2AYO A;  3B79 A;  4MZO A;  2VFC A;  1KHP A;  2GHU A;  2OP3 A;  3ERV A;  1MS6 A;  1VJV A;  2PAD A;  3BPM A;  1CB5 A;  3D9W A;  3DF0 A;  4AXL A;  3WXF A;  1CV8 A;  4QRG A;  3P5V A;  3C9E A;  2FTD A;  2FO5 A;  3MOR A;  5J94 A;  3IUT A;  4MSX A;  1M6D A;  1F2A A;  2PNS A;  1MDW A;  1ME3 A;  1STF E;  2AU1 A;  3KX1 A;  3BPF A;  4NV8 A;  4YYV A;  1KFX L;  1F29 A;  3OF8 A;  1TU6 A;  3PW3 A;  3AI8 A;  2PBH A;  3MHS A;  1U9V A;  4PAD A;  2BDZ A;  2FUD A;  4YYS A;  4MZS A;  4QRX A;  3H7D A;  1PPD A;  3IV2 A;  5F02 A;  2P86 A;  2HD5 A;  3D6S A;  2R9C A;  2DJG B;  1ZIV A;  1NB3 A;  4BQV A;  4W5B A;  2DC6 A;  2G7Y A;  4X6H A;  2R9F A;  3GCB A;  1JQP A;  3HD3 A;  2NQG A;  4QRV A;  4X6J A;  2ATO A;  4K7C A;  2PRE A;  3OVX A;  1ME4 A;  1BQI A;  3ZUA A;  1QDQ A;  1W6F A;  2FRA A;  4HWY A;  1PAD A;  3HWN A;  3I06 A;  4BPV A;  1AU2 A;  1GCB A;  2IPP B;  2YJB A;  3IHP A;  1U9X A;  2AUZ A;  2XU5 A;  3N3K A;  2HXZ A;  1GLO A;  1U5I A;  1NPZ A;  2R9O A;  3H8B A;  3U8E A;  1QOL A;  6PAD A;  4W4U A;  4N79 A;  3OVZ A;  5PAD A;  1QMY A;  1TLO A;  2OZ2 A;  4XUI A;  4G54 A;  2DCB A;  3OF9 A;  1AYU A;  2NQA A;  1CSB B;  2YJ9 A;  1PXV A;  5A24 A;  1DF0 A;  1E2T A;  2XU4 A;  2JQG R;  3KFQ A;  1F2C A;  2E03 A;  4QBB A;  1U9W A;  1GX3 A;  2DC8 A;  2DJF B;  1PE6 A;  1EWO A;  3K8U A;  3S3Q A;  2AVW A;  4NV7 A;  2FQ9 A;  4YV8 A;  2WBF X;  3QJ3 A;  5CHV A;  1SP4 B;  1PIP A;  2FRQ A;  1QXP A;  1U9Q X;  3WXE A;  1YVB A;  1PCI A;  4CZW A;  1CVZ A;  4QH6 A;  2HHN A;  1Y4H A;  3CH3 X;  3KSE A;  7PCK A;  5K16 A;  1ZCM A;  1CQD A;  1AEC A;  4I07 A;  3IOQ A;  3HHI A;  1PPO A;  3WXG A;  1KXR A;  3S3R A;  2FYE A;  3KWB X;  1K3B B;  1AYW A;  3N3G A;  2G8E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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