1ZCMA

Human calpain protease core inhibited by zllych2f
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
321
structure length
321
Chain Sequence
NAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEAFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Calpain 1, large [catalytic] subunit
total genus 98
structure length 321
sequence length 321
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2005-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1zcmA02
3OVZA 3S3QA 2VHFA 3IMAA 4AXLA 4N8WA 2AYNA 3TNXA 1PXVA 4FJCA 1CJLA 3KKUA 3OF8A 1ATKA 2OP3A 3K24A 4QRGA 1GLOA 1AYWA 2DCAA 2NQDB 3H8CA 3KX1A 3KFQA 2WBFX 3E1ZB 3P5WA 3PW3A 1HUCB 5JA7A 3IEJA 4QRVA 1F2CA 1O0EA 2ACTA 3I06A 1AYUA 1ME3A 4OELA 2DC8A 2AIMA 3WXGA 3O1GA 2AU1A 2F7DA 4XUIA 4YYQA 2FRAA 4DMYA 2E00A 4PP1A 2DC9A 3HHIA 4G54A 2R9OA 1BGOA 4X6HA 2IPPB 1U9WA 3P5UA 1FH0A 2YJCA 1CVZA 2R9MA 2DCBA 2CB5A 1BY8A 3RVVA 4CZWA 3N3GA 1VSNA 1EWLA 1DEUA 1KFXL 1JQPA 3HHAA 3CBKA 3I3TA 1PPNA 4Q8GA 1AYVA 1CB5A 2O6XA 2P86A 3PDFA 1YVBA 1GCBA 4I04A 2HD5A 1U9VA 1PIPA 4MZOA 2XU3A 1MDWA 2BDLA 2P0RA 4N4ZA 4YYSA 2PNSA 3HD3A 3PBHA 3OF9A 3BOWA 1MS6A 1NPZA 2AYOA 4YYUA 4CDDB 4MSXA 2Y6EA 4X6JA 2DCDA 3OVXA 3U8EA 2FT2A 1QDQA 3CH2X 1CQDA 3KWBX 1PPOA 1EWOA 4I07A 1Q6KA 1S4VA 1NLJA 2H7JA 2CIOA 2DC7A 4W4UA 3MTNA 3O0UA 5EF4A 3V6EA 4W5CA 2ATOA 1QMYA 2DZYA 4FK5A 1ME4A 5CHTA 5F02A 2FRQA 1PADA 3H89A 1ICFA 3IUTA 3IHPA 1MIRA 2HHNA 2G6DA 2FYEA 3OISA 3BC3A 2YJ2A 2G8JA 8PCHA 1POPA 1ZCMA 1DF0A 1GMYA 4QBBA 3KW9A 4X6IA 1YT7A 2E02A 2OULA 1QOLA 3V6CA 1X9YA 1AECA 1U9QX 3AI8A 1M6DA 1STFE 4QRXA 3N4CA 5EGWA 2R9CA 3BCNA 3PNRA 5PADA 1SNKA 1YK8A 1YALA 7PCKA 5K16A 1CTEA 2VHSA 3H8BA 1KHQA 3WXEA 1AU0A 3QJ3A 4KLBA 4HWYA 1Y08A 1TU6A 3KWZA 5A24A 2AS8A 4PI3A 1MEMA 1CPJA 3P5VA 1THEA 4PADA 2HXZA 2JQFR 3MHSA 2FTDA 1NQCA 1CSBB 4PP2E 1PCIA 4YV8A 4XR7A 3NHEA 1F2BA 3BPMA 3LXSA 2AUZA 4P6EA 5CVNB 3K8UA 9PAPA 3CH3X 2B1NA 3HWNA 4K7CA 2DCCA 1AU2A 2PREA 2Y5BA 2AVWA 2OZ2A 3S3RA 2HH5A 3USVA 2R9FA 1BQIA 1AU4A 1BP4A 2P7UA 3P5XA 5FPWA 2E03A 2R6NA 3IV2A 5CVOB 1VJVA 1U9XA 5CVMA 1CS8A 3MHHA 2PADA 2IBIA 2DJFB 2G8EA 4BQVA 4W5BA 4YVAA 3QSDA 1Y4HA 3CBJA 2NQGA 3LFYA 2AUXA 3IOQA 4WA6A 2GHUA 2G7YA 1PBHA 3RVXA 1AIMA 2E01A 3H6SA 4MZSA 4OEMA 2GFOA 1IWDA 4YYWA 3N3KA 2FUDA 1PE6A 2DJGB 4CDEB 1EF7A 1A6RA 3M99A 5CHVA 2BDZA 3B79A 4RY2A 4P6GA 2FO5A 3MORA 4CDCB 1TLOA 3KSEA 2YJBA 3BPFA 4AXMA 4Q8HA 3BWKA 1NB3A 3F75A 1AU3A 2NQAA 3K9MA 2FQ9A 3GCBA 4ZUXU 1SP4B 6PADA 1YK7A 4YYVA 2DC6A 2R9NA 1EWPA 1PPDA 2JQGR 2XU4A 1ITOA 1QXPA 5JH3A 3DF0A 4FIPA 1F29A 2XU1A 2YJ9A 1XKGA 4BPVA 2XU5A 2YJ8A 2PBHA 4BSQA 3C9EA 1PPPA 2B1MA 3D6SA 4N79A 3ERVA 1GECE 1TL9A 5J94A 1KXRA 1K3BB 1MEGA 1MHWA 4CDFB 1NL6A 4I05A 4BS6A 3H7DA 1KHPA 2NQIA 2ARYA 4QH6A 1KFUL 1CV8A 4YYRA 1ZIVA 3ZUAA 2C0YA 3QT4A 4DMXA 2DZZA 1U5IA 3RVWA 3F5VA 3WXFA 1F2AA 1EWMA 2F1GA 4BS5A 1NB5A
chains in the Genus database with same CATH superfamily
3OVZA 3S3QA 4HXDB 2VHFA 3IMAA 4AXLA 1DKIA 4N8WA 4XZXA 2AYNA 3TNXA 3TRKA 1PXVA 4FJCA 1CJLA 5JZEA 3KKUA 3OF8A 1ATKA 1UKFA 2OP3A 3K24A 4QRGA 1GLOA 1AYWA 2DCAA 2NQDB 3H8CA 3KX1A 3KFQA 2WBFX 3E1ZB 4WURA 3P5WA 3PW3A 1HUCB 5JA7A 2HWKA 3IEJA 4QRVA 1F2CA 4BOQA 1O0EA 2ACTA 3I06A 1AYUA 1ME3A 4A5UA 4OELA 2DC8A 2AIMA 3WXGA 3O1GA 3MJ5A 2AU1A 2F7DA 4XUIA 4YYQA 2FRAA 1YZBA 3PRPA 4RF0A 4DMYA 2E00A 4PP1A 2DC9A 3HHIA 4G54A 2R9OA 1BGOA 4X6HA 2IPPB 1U9WA 3P5UA 1FH0A 2YJCA 4BOZA 1CVZA 2R9MA 2DCBA 2CB5A 2JTCA 1BY8A 3RVVA 4CZWA 3N3GA 1VSNA 3W30A 1EWLA 1DEUA 1KFXL 1JQPA 3HHAA 5EZSA 3CBKA 3I3TA 1PPNA 4Q8GA 1AYVA 1CB5A 2O6XA 2P86A 3PDFA 3ZNHA 1YVBA 1GCBA 2HD5A 4I04A 4OVZB 1U9VA 1PIPA 3BB7A 4MZOA 2XU3A 1MDWA 2BDLA 2P0RA 4N4ZA 4YYSA 2PNSA 3HD3A 3PBHA 3OF9A 3BOWA 4RF1A 1MS6A 1NPZA 2AYOA 4YYUA 4CDDB 4MSXA 2Y6EA 4X6JA 2DCDA 3OVXA 3U8EA 2FT2A 1QDQA 3CH2X 1CQDA 3KWBX 1PPOA 1EWOA 4I07A 1Q6KA 1S4VA 1NLJA 2H7JA 2CIOA 4MM3B 2DC7A 4W4UA 3MTNA 3O0UA 2BTWA 5EF4A 3V6EA 4W5CA 4BOPA 2ATOA 1QMYA 2DZYA 4FK5A 1ME4A 5CHTA 5EZQA 2FRQA 5F02A 1PADA 3H89A 1ICFA 4IP3A 3IUTA 3IHPA 1MIRA 3MTVA 4REZA 2HHNA 2G6DA 2FYEA 3OISA 4RNAA 3BC3A 2YJ2A 2G8JA 8PCHA 1POPA 1ZCMA 1DF0A 1GMYA 4QBBA 3KW9A 4X6IA 1YT7A 2E02A 2OULA 1QOLA 3V6CA 1X9YA 1AECA 1U9QX 3AI8A 3PT2A 3RNVA 1M6DA 3O65A 1STFE 4QRXA 4D8IA 3N4CA 5EGWA 3C0RA 2R9CA 3BCNA 3PNRA 4PT5A 5PADA 1SNKA 3B21A 1YK8A 1YALA 7PCKA 5K16A 1CTEA 2VHSA 3H8BA 1KHQA 2J7QC 3WXEA 1AU0A 4OW0A 3QJ3A 4KLBA 4HWYA 1Y08A 1TU6A 3KWZA 3OQCA 5A24A 2AS8A 4PI3A 1MEMA 2BU3A 1CPJA 3P5VA 1THEA 2Z84A 4PADA 2HXZA 2JQFR 3MHSA 2FTDA 1NQCA 1CSBB 4PP2E 1PCIA 4YV8A 4XR7A 3NHEA 1F2BA 3BPMA 3LXSA 2AUZA 4P6EA 5CVNB 3K8UA 9PAPA 3CH3X 2B1NA 3HWNA 3MP2A 2AGAA 4K7CA 2DCCA 1AU2A 2PREA 2Y5BA 2AVWA 2OZ2A 3S3RA 5KO3A 2HH5A 3TMPA 3USVA 2R9FA 5E6JA 1BQIA 3BY4A 1AU4A 3W31A 1BP4A 2P7UA 3P5XA 5FPWA 2E03A 4P16A 2R6NA 4R3DA 3IV2A 5CVOB 1VJVA 1U9XA 5CVMA 1CS8A 3MHHA 2PADA 2IBIA 2DJFB 2JRIA 2G8EA 4BQVA 4W5BA 4YVAA 3QSDA 1Y4HA 3PHXA 3CBJA 2NQGA 3LFYA 2AUXA 3IOQA 3PHUA 4IUMA 4WA6A 4BOUA 2GHUA 2G7YA 1PBHA 3RVXA 1AIMA 2E01A 3H6SA 4M0WA 4MZSA 4OEMA 2GFOA 1IWDA 4YYWA 3N3KA 2FUDA 1PE6A 2DJGB 4CDEB 1EF7A 1A6RA 3M99A 3IFUA 4OVZA 5CHVA 2BDZA 3B79A 4RY2A 4P6GA 2FO5A 3MORA 4CDCB 1TLOA 3KSEA 2YJBA 3BPFA 4AXMA 4Q8HA 3BWKA 2DOSA 1NB3A 3F75A 1AU3A 3E9SA 2NQAA 3K9MA 2FQ9A 4MI7A 1PVJA 3GCBA 4ZUXU 1SP4B 2BTWB 2UZJA 6PADA 1YK7A 2J7QA 4YYVA 2DC6A 2R9NA 1EWPA 1PPDA 4GUAA 4BOSA 2JQGR 2XU4A 1ITOA 1QXPA 5JH3A 2FE8A 3DF0A 4FIPA 1F29A 2XU1A 2YJ9A 1XKGA 4BPVA 2XU5A 2YJ8A 2PBHA 4BSQA 3C9EA 1PPPA 3PHWA 2B1MA 3D6SA 3PSEA 4N79A 4RKXA 3BBAA 3ERVA 1GECE 1TL9A 5J94A 1KXRA 1K3BB 1MEGA 1MHWA 4CDFB 1NL6A 4I05A 4BS6A 3PRMA 4D8BA 3H7DA 1KHPA 2NQIA 2ARYA 4QH6A 1KFUL 4D8EA 1CV8A 4YYRA 1ZIVA 3ZUAA 2C0YA 3QT4A 4DMXA 2DZZA 1U5IA 3RVWA 4ZTBA 3F5VA 3WXFA 1F2AA 1EWMA 2F1GA 4BS5A 1NB5A
chains in the Genus database with same CATH topology
3OVZA 3S3QA 2VHFA 3IMAA 4AXLA 4N8WA 2AYNA 3TNXA 1PXVA 4FJCA 1CJLA 3KKUA 3OF8A 1ATKA 2VFBA 2OP3A 3K24A 4QRGA 1GLOA 1AYWA 1W6FA 2DCAA 2NQDB 3H8CA 3KX1A 3KFQA 2WBFX 3E1ZB 3P5WA 3PW3A 1HUCB 5JA7A 3IEJA 4QRVA 1F2CA 1O0EA 2ACTA 3I06A 1AYUA 1ME3A 4OELA 2DC8A 2AIMA 3WXGA 3O1GA 4NV7A 1W4TA 2AU1A 2F7DA 4XUIA 4YYQA 2FRAA 4DMYA 2E00A 4PP1A 2DC9A 3HHIA 4G54A 2R9OA 1BGOA 4X6HA 2IPPB 1U9WA 3P5UA 1FH0A 2YJCA 1CVZA 2R9MA 2DCBA 2CB5A 1BY8A 4B55A 3RVVA 4CZWA 3N3GA 1VSNA 1EWLA 1DEUA 4BGFA 1KFXL 1JQPA 3HHAA 3CBKA 3I3TA 1PPNA 4Q8GA 1AYVA 1CB5A 2O6XA 2P86A 3PDFA 1YVBA 1GCBA 4I04A 2HD5A 1U9VA 2BSZA 1PIPA 4MZOA 2XU3A 1MDWA 2BDLA 2P0RA 4N4ZA 4YYSA 2PNSA 3HD3A 3PBHA 3OF9A 3BOWA 1MS6A 1NPZA 2AYOA 4YYUA 4CDDB 3D9WA 4MSXA 2Y6EA 4X6JA 2DCDA 3OVXA 3U8EA 2FT2A 1QDQA 3CH2X 1CQDA 3KWBX 1PPOA 1EWOA 4I07A 1Q6KA 1S4VA 1NLJA 2H7JA 2CIOA 2DC7A 4W4UA 3MTNA 3O0UA 5EF4A 3V6EA 4W5CA 2ATOA 1QMYA 2DZYA 4FK5A 1ME4A 5CHTA 5F02A 2FRQA 1PADA 3H89A 1ICFA 3IUTA 3IHPA 1MIRA 2HHNA 2G6DA 2FYEA 3OISA 3BC3A 2YJ2A 2G8JA 8PCHA 1POPA 1ZCMA 1DF0A 1GMYA 4QBBA 3LTWA 3KW9A 4X6IA 1YT7A 2E02A 2OULA 1QOLA 3V6CA 1X9YA 1AECA 1U9QX 3AI8A 1M6DA 1STFE 4QRXA 3N4CA 5EGWA 2R9CA 3BCNA 3PNRA 5PADA 1SNKA 1YK8A 1YALA 7PCKA 5K16A 1CTEA 2VHSA 3H8BA 1KHQA 3WXEA 1AU0A 3QJ3A 4KLBA 4HWYA 1Y08A 1TU6A 3KWZA 5A24A 2AS8A 4PI3A 1MEMA 1E2TA 1CPJA 3P5VA 1THEA 4PADA 2HXZA 2JQFR 3MHSA 2FTDA 1NQCA 1CSBB 4PP2E 1PCIA 4YV8A 4XR7A 3NHEA 1F2BA 3BPMA 3LXSA 2AUZA 4P6EA 5CVNB 3K8UA 9PAPA 3CH3X 2B1NA 3HWNA 4K7CA 2DCCA 1AU2A 2PREA 2Y5BA 2AVWA 2OZ2A 3S3RA 2HH5A 3USVA 2R9FA 1BQIA 1AU4A 1BP4A 2P7UA 3P5XA 5FPWA 2E03A 2R6NA 3IV2A 5CVOB 1VJVA 1U9XA 5CVMA 1CS8A 3MHHA 2PADA 2IBIA 2DJFB 2G8EA 4BQVA 4W5BA 4YVAA 3QSDA 1Y4HA 3CBJA 2NQGA 3LFYA 2AUXA 3IOQA 4WA6A 2GHUA 2G7YA 1PBHA 3RVXA 1AIMA 2E01A 3H6SA 4MZSA 4OEMA 2GFOA 1IWDA 4YYWA 3N3KA 2FUDA 1PE6A 2DJGB 4CDEB 1EF7A 1A6RA 3M99A 5CHVA 2BDZA 3B79A 4RY2A 4P6GA 2FO5A 3MORA 4CDCB 1TLOA 3KSEA 2YJBA 3BPFA 4AXMA 4Q8HA 3BWKA 1NB3A 3F75A 1AU3A 1GX3A 2NQAA 3K9MA 2FQ9A 4C5PA 3GCBA 4ZUXU 1SP4B 6PADA 1YK7A 4YYVA 2DC6A 2R9NA 1EWPA 1PPDA 4NV8A 2JQGR 2XU4A 1ITOA 1QXPA 5JH3A 3DF0A 4FIPA 1F29A 2XU1A 2YJ9A 1XKGA 4BPVA 2XU5A 2YJ8A 2PBHA 4BSQA 3C9EA 1PPPA 2B1MA 3D6SA 4N79A 3ERVA 2VFCA 4GUZA 1GECE 1TL9A 5J94A 1KXRA 1K3BB 1MEGA 1MHWA 4CDFB 1NL6A 4I05A 4BS6A 3H7DA 1KHPA 2NQIA 2ARYA 4QH6A 1KFUL 1CV8A 4YYRA 1ZIVA 1W5RA 3ZUAA 2C0YA 3QT4A 4DMXA 2DZZA 1U5IA 3RVWA 3F5VA 3WXFA 1F2AA 1EWMA 2F1GA 4BS5A 1NB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OVZ A;  3S3Q A;  2VHF A;  3IMA A;  4AXL A;  4N8W A;  2AYN A;  3TNX A;  1PXV A;  4FJC A;  1CJL A;  3KKU A;  3OF8 A;  1ATK A;  2OP3 A;  3K24 A;  4QRG A;  1GLO A;  1AYW A;  2DCA A;  2NQD B;  3H8C A;  3KX1 A;  3KFQ A;  2WBF X;  3E1Z B;  3P5W A;  3PW3 A;  1HUC B;  5JA7 A;  3IEJ A;  4QRV A;  1F2C A;  1O0E A;  2ACT A;  3I06 A;  1AYU A;  1ME3 A;  4OEL A;  2DC8 A;  2AIM A;  3WXG A;  3O1G A;  2AU1 A;  2F7D A;  4XUI A;  4YYQ A;  2FRA A;  4DMY A;  2E00 A;  4PP1 A;  2DC9 A;  3HHI A;  4G54 A;  2R9O A;  1BGO A;  4X6H A;  2IPP B;  1U9W A;  3P5U A;  1FH0 A;  2YJC A;  1CVZ A;  2R9M A;  2DCB A;  2CB5 A;  1BY8 A;  3RVV A;  4CZW A;  3N3G A;  1VSN A;  1EWL A;  1DEU A;  1KFX L;  1JQP A;  3HHA A;  3CBK A;  3I3T A;  1PPN A;  4Q8G A;  1AYV A;  1CB5 A;  2O6X A;  2P86 A;  3PDF A;  1YVB A;  1GCB A;  4I04 A;  2HD5 A;  1U9V A;  1PIP A;  4MZO A;  2XU3 A;  1MDW A;  2BDL A;  2P0R A;  4N4Z A;  4YYS A;  2PNS A;  3HD3 A;  3PBH A;  3OF9 A;  3BOW A;  1MS6 A;  1NPZ A;  2AYO A;  4YYU A;  4CDD B;  4MSX A;  2Y6E A;  4X6J A;  2DCD A;  3OVX A;  3U8E A;  2FT2 A;  1QDQ A;  3CH2 X;  1CQD A;  3KWB X;  1PPO A;  1EWO A;  4I07 A;  1Q6K A;  1S4V A;  1NLJ A;  2H7J A;  2CIO A;  2DC7 A;  4W4U A;  3MTN A;  3O0U A;  5EF4 A;  3V6E A;  4W5C A;  2ATO A;  1QMY A;  2DZY A;  4FK5 A;  1ME4 A;  5CHT A;  5F02 A;  2FRQ A;  1PAD A;  3H89 A;  1ICF A;  3IUT A;  3IHP A;  1MIR A;  2HHN A;  2G6D A;  2FYE A;  3OIS A;  3BC3 A;  2YJ2 A;  2G8J A;  8PCH A;  1POP A;  1ZCM A;  1DF0 A;  1GMY A;  4QBB A;  3KW9 A;  4X6I A;  1YT7 A;  2E02 A;  2OUL A;  1QOL A;  3V6C A;  1X9Y A;  1AEC A;  1U9Q X;  3AI8 A;  1M6D A;  1STF E;  4QRX A;  3N4C A;  5EGW A;  2R9C A;  3BCN A;  3PNR A;  5PAD A;  1SNK A;  1YK8 A;  1YAL A;  7PCK A;  5K16 A;  1CTE A;  2VHS A;  3H8B A;  1KHQ A;  3WXE A;  1AU0 A;  3QJ3 A;  4KLB A;  4HWY A;  1Y08 A;  1TU6 A;  3KWZ A;  5A24 A;  2AS8 A;  4PI3 A;  1MEM A;  1CPJ A;  3P5V A;  1THE A;  4PAD A;  2HXZ A;  2JQF R;  3MHS A;  2FTD A;  1NQC A;  1CSB B;  4PP2 E;  1PCI A;  4YV8 A;  4XR7 A;  3NHE A;  1F2B A;  3BPM A;  3LXS A;  2AUZ A;  4P6E A;  5CVN B;  3K8U A;  9PAP A;  3CH3 X;  2B1N A;  3HWN A;  4K7C A;  2DCC A;  1AU2 A;  2PRE A;  2Y5B A;  2AVW A;  2OZ2 A;  3S3R A;  2HH5 A;  3USV A;  2R9F A;  1BQI A;  1AU4 A;  1BP4 A;  2P7U A;  3P5X A;  5FPW A;  2E03 A;  2R6N A;  3IV2 A;  5CVO B;  1VJV A;  1U9X A;  5CVM A;  1CS8 A;  3MHH A;  2PAD A;  2IBI A;  2DJF B;  2G8E A;  4BQV A;  4W5B A;  4YVA A;  3QSD A;  1Y4H A;  3CBJ A;  2NQG A;  3LFY A;  2AUX A;  3IOQ A;  4WA6 A;  2GHU A;  2G7Y A;  1PBH A;  3RVX A;  1AIM A;  2E01 A;  3H6S A;  4MZS A;  4OEM A;  2GFO A;  1IWD A;  4YYW A;  3N3K A;  2FUD A;  1PE6 A;  2DJG B;  4CDE B;  1EF7 A;  1A6R A;  3M99 A;  5CHV A;  2BDZ A;  3B79 A;  4RY2 A;  4P6G A;  2FO5 A;  3MOR A;  4CDC B;  1TLO A;  3KSE A;  2YJB A;  3BPF A;  4AXM A;  4Q8H A;  3BWK A;  1NB3 A;  3F75 A;  1AU3 A;  2NQA A;  3K9M A;  2FQ9 A;  3GCB A;  4ZUX U;  1SP4 B;  6PAD A;  1YK7 A;  4YYV A;  2DC6 A;  2R9N A;  1EWP A;  1PPD A;  2JQG R;  2XU4 A;  1ITO A;  1QXP A;  5JH3 A;  3DF0 A;  4FIP A;  1F29 A;  2XU1 A;  2YJ9 A;  1XKG A;  4BPV A;  2XU5 A;  2YJ8 A;  2PBH A;  4BSQ A;  3C9E A;  1PPP A;  2B1M A;  3D6S A;  4N79 A;  3ERV A;  1GEC E;  1TL9 A;  5J94 A;  1KXR A;  1K3B B;  1MEG A;  1MHW A;  4CDF B;  1NL6 A;  4I05 A;  4BS6 A;  3H7D A;  1KHP A;  2NQI A;  2ARY A;  4QH6 A;  1KFU L;  1CV8 A;  4YYR A;  1ZIV A;  3ZUA A;  2C0Y A;  3QT4 A;  4DMX A;  2DZZ A;  1U5I A;  3RVW A;  3F5V A;  3WXF A;  1F2A A;  1EWM A;  2F1G A;  4BS5 A;  1NB5 A; 
#chains in the Genus database with same CATH topology
 3OVZ A;  3S3Q A;  4HXD B;  2VHF A;  3IMA A;  4AXL A;  1DKI A;  4N8W A;  4XZX A;  2AYN A;  3TNX A;  3TRK A;  1PXV A;  4FJC A;  1CJL A;  5JZE A;  3KKU A;  3OF8 A;  1ATK A;  1UKF A;  2OP3 A;  3K24 A;  4QRG A;  1GLO A;  1AYW A;  2DCA A;  2NQD B;  3H8C A;  3KX1 A;  3KFQ A;  2WBF X;  3E1Z B;  4WUR A;  3P5W A;  3PW3 A;  1HUC B;  5JA7 A;  2HWK A;  3IEJ A;  4QRV A;  1F2C A;  4BOQ A;  1O0E A;  2ACT A;  3I06 A;  1AYU A;  1ME3 A;  4A5U A;  4OEL A;  2DC8 A;  2AIM A;  3WXG A;  3O1G A;  3MJ5 A;  2AU1 A;  2F7D A;  4XUI A;  4YYQ A;  2FRA A;  1YZB A;  3PRP A;  4RF0 A;  4DMY A;  2E00 A;  4PP1 A;  2DC9 A;  3HHI A;  4G54 A;  2R9O A;  1BGO A;  4X6H A;  2IPP B;  1U9W A;  3P5U A;  1FH0 A;  2YJC A;  4BOZ A;  1CVZ A;  2R9M A;  2DCB A;  2CB5 A;  2JTC A;  1BY8 A;  3RVV A;  4CZW A;  3N3G A;  1VSN A;  3W30 A;  1EWL A;  1DEU A;  1KFX L;  1JQP A;  3HHA A;  5EZS A;  3CBK A;  3I3T A;  1PPN A;  4Q8G A;  1AYV A;  1CB5 A;  2O6X A;  2P86 A;  3PDF A;  3ZNH A;  1YVB A;  1GCB A;  2HD5 A;  4I04 A;  4OVZ B;  1U9V A;  1PIP A;  3BB7 A;  4MZO A;  2XU3 A;  1MDW A;  2BDL A;  2P0R A;  4N4Z A;  4YYS A;  2PNS A;  3HD3 A;  3PBH A;  3OF9 A;  3BOW A;  4RF1 A;  1MS6 A;  1NPZ A;  2AYO A;  4YYU A;  4CDD B;  4MSX A;  2Y6E A;  4X6J A;  2DCD A;  3OVX A;  3U8E A;  2FT2 A;  1QDQ A;  3CH2 X;  1CQD A;  3KWB X;  1PPO A;  1EWO A;  4I07 A;  1Q6K A;  1S4V A;  1NLJ A;  2H7J A;  2CIO A;  4MM3 B;  2DC7 A;  4W4U A;  3MTN A;  3O0U A;  2BTW A;  5EF4 A;  3V6E A;  4W5C A;  4BOP A;  2ATO A;  1QMY A;  2DZY A;  4FK5 A;  1ME4 A;  5CHT A;  5EZQ A;  2FRQ A;  5F02 A;  1PAD A;  3H89 A;  1ICF A;  4IP3 A;  3IUT A;  3IHP A;  1MIR A;  3MTV A;  4REZ A;  2HHN A;  2G6D A;  2FYE A;  3OIS A;  4RNA A;  3BC3 A;  2YJ2 A;  2G8J A;  8PCH A;  1POP A;  1ZCM A;  1DF0 A;  1GMY A;  4QBB A;  3KW9 A;  4X6I A;  1YT7 A;  2E02 A;  2OUL A;  1QOL A;  3V6C A;  1X9Y A;  1AEC A;  1U9Q X;  3AI8 A;  3PT2 A;  3RNV A;  1M6D A;  3O65 A;  1STF E;  4QRX A;  4D8I A;  3N4C A;  5EGW A;  3C0R A;  2R9C A;  3BCN A;  3PNR A;  4PT5 A;  5PAD A;  1SNK A;  3B21 A;  1YK8 A;  1YAL A;  7PCK A;  5K16 A;  1CTE A;  2VHS A;  3H8B A;  1KHQ A;  2J7Q C;  3WXE A;  1AU0 A;  4OW0 A;  3QJ3 A;  4KLB A;  4HWY A;  1Y08 A;  1TU6 A;  3KWZ A;  3OQC A;  5A24 A;  2AS8 A;  4PI3 A;  1MEM A;  2BU3 A;  1CPJ A;  3P5V A;  1THE A;  2Z84 A;  4PAD A;  2HXZ A;  2JQF R;  3MHS A;  2FTD A;  1NQC A;  1CSB B;  4PP2 E;  1PCI A;  4YV8 A;  4XR7 A;  3NHE A;  1F2B A;  3BPM A;  3LXS A;  2AUZ A;  4P6E A;  5CVN B;  3K8U A;  9PAP A;  3CH3 X;  2B1N A;  3HWN A;  3MP2 A;  2AGA A;  4K7C A;  2DCC A;  1AU2 A;  2PRE A;  2Y5B A;  2AVW A;  2OZ2 A;  3S3R A;  5KO3 A;  2HH5 A;  3TMP A;  3USV A;  2R9F A;  5E6J A;  1BQI A;  3BY4 A;  1AU4 A;  3W31 A;  1BP4 A;  2P7U A;  3P5X A;  5FPW A;  2E03 A;  4P16 A;  2R6N A;  4R3D A;  3IV2 A;  5CVO B;  1VJV A;  1U9X A;  5CVM A;  1CS8 A;  3MHH A;  2PAD A;  2IBI A;  2DJF B;  2JRI A;  2G8E A;  4BQV A;  4W5B A;  4YVA A;  3QSD A;  1Y4H A;  3PHX A;  3CBJ A;  2NQG A;  3LFY A;  2AUX A;  3IOQ A;  3PHU A;  4IUM A;  4WA6 A;  4BOU A;  2GHU A;  2G7Y A;  1PBH A;  3RVX A;  1AIM A;  2E01 A;  3H6S A;  4M0W A;  4MZS A;  4OEM A;  2GFO A;  1IWD A;  4YYW A;  3N3K A;  2FUD A;  1PE6 A;  2DJG B;  4CDE B;  1EF7 A;  1A6R A;  3M99 A;  3IFU A;  4OVZ A;  5CHV A;  2BDZ A;  3B79 A;  4RY2 A;  4P6G A;  2FO5 A;  3MOR A;  4CDC B;  1TLO A;  3KSE A;  2YJB A;  3BPF A;  4AXM A;  4Q8H A;  3BWK A;  2DOS A;  1NB3 A;  3F75 A;  1AU3 A;  3E9S A;  2NQA A;  3K9M A;  2FQ9 A;  4MI7 A;  1PVJ A;  3GCB A;  4ZUX U;  1SP4 B;  2BTW B;  2UZJ A;  6PAD A;  1YK7 A;  2J7Q A;  4YYV A;  2DC6 A;  2R9N A;  1EWP A;  1PPD A;  4GUA A;  4BOS A;  2JQG R;  2XU4 A;  1ITO A;  1QXP A;  5JH3 A;  2FE8 A;  3DF0 A;  4FIP A;  1F29 A;  2XU1 A;  2YJ9 A;  1XKG A;  4BPV A;  2XU5 A;  2YJ8 A;  2PBH A;  4BSQ A;  3C9E A;  1PPP A;  3PHW A;  2B1M A;  3D6S A;  3PSE A;  4N79 A;  4RKX A;  3BBA A;  3ERV A;  1GEC E;  1TL9 A;  5J94 A;  1KXR A;  1K3B B;  1MEG A;  1MHW A;  4CDF B;  1NL6 A;  4I05 A;  4BS6 A;  3PRM A;  4D8B A;  3H7D A;  1KHP A;  2NQI A;  2ARY A;  4QH6 A;  1KFU L;  4D8E A;  1CV8 A;  4YYR A;  1ZIV A;  3ZUA A;  2C0Y A;  3QT4 A;  4DMX A;  2DZZ A;  1U5I A;  3RVW A;  4ZTB A;  3F5V A;  3WXF A;  1F2A A;  1EWM A;  2F1G A;  4BS5 A;  1NB5 A; 
#chains in the Genus database with same CATH homology
 3OVZ A;  3S3Q A;  2VHF A;  3IMA A;  4AXL A;  4N8W A;  2AYN A;  3TNX A;  1PXV A;  4FJC A;  1CJL A;  3KKU A;  3OF8 A;  1ATK A;  2VFB A;  2OP3 A;  3K24 A;  4QRG A;  1GLO A;  1AYW A;  1W6F A;  2DCA A;  2NQD B;  3H8C A;  3KX1 A;  3KFQ A;  2WBF X;  3E1Z B;  3P5W A;  3PW3 A;  1HUC B;  5JA7 A;  3IEJ A;  4QRV A;  1F2C A;  1O0E A;  2ACT A;  3I06 A;  1AYU A;  1ME3 A;  4OEL A;  2DC8 A;  2AIM A;  3WXG A;  3O1G A;  4NV7 A;  1W4T A;  2AU1 A;  2F7D A;  4XUI A;  4YYQ A;  2FRA A;  4DMY A;  2E00 A;  4PP1 A;  2DC9 A;  3HHI A;  4G54 A;  2R9O A;  1BGO A;  4X6H A;  2IPP B;  1U9W A;  3P5U A;  1FH0 A;  2YJC A;  1CVZ A;  2R9M A;  2DCB A;  2CB5 A;  1BY8 A;  4B55 A;  3RVV A;  4CZW A;  3N3G A;  1VSN A;  1EWL A;  1DEU A;  4BGF A;  1KFX L;  1JQP A;  3HHA A;  3CBK A;  3I3T A;  1PPN A;  4Q8G A;  1AYV A;  1CB5 A;  2O6X A;  2P86 A;  3PDF A;  1YVB A;  1GCB A;  4I04 A;  2HD5 A;  1U9V A;  2BSZ A;  1PIP A;  4MZO A;  2XU3 A;  1MDW A;  2BDL A;  2P0R A;  4N4Z A;  4YYS A;  2PNS A;  3HD3 A;  3PBH A;  3OF9 A;  3BOW A;  1MS6 A;  1NPZ A;  2AYO A;  4YYU A;  4CDD B;  3D9W A;  4MSX A;  2Y6E A;  4X6J A;  2DCD A;  3OVX A;  3U8E A;  2FT2 A;  1QDQ A;  3CH2 X;  1CQD A;  3KWB X;  1PPO A;  1EWO A;  4I07 A;  1Q6K A;  1S4V A;  1NLJ A;  2H7J A;  2CIO A;  2DC7 A;  4W4U A;  3MTN A;  3O0U A;  5EF4 A;  3V6E A;  4W5C A;  2ATO A;  1QMY A;  2DZY A;  4FK5 A;  1ME4 A;  5CHT A;  5F02 A;  2FRQ A;  1PAD A;  3H89 A;  1ICF A;  3IUT A;  3IHP A;  1MIR A;  2HHN A;  2G6D A;  2FYE A;  3OIS A;  3BC3 A;  2YJ2 A;  2G8J A;  8PCH A;  1POP A;  1ZCM A;  1DF0 A;  1GMY A;  4QBB A;  3LTW A;  3KW9 A;  4X6I A;  1YT7 A;  2E02 A;  2OUL A;  1QOL A;  3V6C A;  1X9Y A;  1AEC A;  1U9Q X;  3AI8 A;  1M6D A;  1STF E;  4QRX A;  3N4C A;  5EGW A;  2R9C A;  3BCN A;  3PNR A;  5PAD A;  1SNK A;  1YK8 A;  1YAL A;  7PCK A;  5K16 A;  1CTE A;  2VHS A;  3H8B A;  1KHQ A;  3WXE A;  1AU0 A;  3QJ3 A;  4KLB A;  4HWY A;  1Y08 A;  1TU6 A;  3KWZ A;  5A24 A;  2AS8 A;  4PI3 A;  1MEM A;  1E2T A;  1CPJ A;  3P5V A;  1THE A;  4PAD A;  2HXZ A;  2JQF R;  3MHS A;  2FTD A;  1NQC A;  1CSB B;  4PP2 E;  1PCI A;  4YV8 A;  4XR7 A;  3NHE A;  1F2B A;  3BPM A;  3LXS A;  2AUZ A;  4P6E A;  5CVN B;  3K8U A;  9PAP A;  3CH3 X;  2B1N A;  3HWN A;  4K7C A;  2DCC A;  1AU2 A;  2PRE A;  2Y5B A;  2AVW A;  2OZ2 A;  3S3R A;  2HH5 A;  3USV A;  2R9F A;  1BQI A;  1AU4 A;  1BP4 A;  2P7U A;  3P5X A;  5FPW A;  2E03 A;  2R6N A;  3IV2 A;  5CVO B;  1VJV A;  1U9X A;  5CVM A;  1CS8 A;  3MHH A;  2PAD A;  2IBI A;  2DJF B;  2G8E A;  4BQV A;  4W5B A;  4YVA A;  3QSD A;  1Y4H A;  3CBJ A;  2NQG A;  3LFY A;  2AUX A;  3IOQ A;  4WA6 A;  2GHU A;  2G7Y A;  1PBH A;  3RVX A;  1AIM A;  2E01 A;  3H6S A;  4MZS A;  4OEM A;  2GFO A;  1IWD A;  4YYW A;  3N3K A;  2FUD A;  1PE6 A;  2DJG B;  4CDE B;  1EF7 A;  1A6R A;  3M99 A;  5CHV A;  2BDZ A;  3B79 A;  4RY2 A;  4P6G A;  2FO5 A;  3MOR A;  4CDC B;  1TLO A;  3KSE A;  2YJB A;  3BPF A;  4AXM A;  4Q8H A;  3BWK A;  1NB3 A;  3F75 A;  1AU3 A;  1GX3 A;  2NQA A;  3K9M A;  2FQ9 A;  4C5P A;  3GCB A;  4ZUX U;  1SP4 B;  6PAD A;  1YK7 A;  4YYV A;  2DC6 A;  2R9N A;  1EWP A;  1PPD A;  4NV8 A;  2JQG R;  2XU4 A;  1ITO A;  1QXP A;  5JH3 A;  3DF0 A;  4FIP A;  1F29 A;  2XU1 A;  2YJ9 A;  1XKG A;  4BPV A;  2XU5 A;  2YJ8 A;  2PBH A;  4BSQ A;  3C9E A;  1PPP A;  2B1M A;  3D6S A;  4N79 A;  3ERV A;  2VFC A;  4GUZ A;  1GEC E;  1TL9 A;  5J94 A;  1KXR A;  1K3B B;  1MEG A;  1MHW A;  4CDF B;  1NL6 A;  4I05 A;  4BS6 A;  3H7D A;  1KHP A;  2NQI A;  2ARY A;  4QH6 A;  1KFU L;  1CV8 A;  4YYR A;  1ZIV A;  1W5R A;  3ZUA A;  2C0Y A;  3QT4 A;  4DMX A;  2DZZ A;  1U5I A;  3RVW A;  3F5V A;  3WXF A;  1F2A A;  1EWM A;  2F1G A;  4BS5 A;  1NB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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