1YVBA

The plasmodium falciparum cysteine protease falcipain-2
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
241
structure length
241
Chain Sequence
QMNYEEVIKKYRGEENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGECGDQLNHAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Plasmodium falciparum
molecule keywords falcipain 2
total genus 61
structure length 241
sequence length 241
ec nomenclature ec 3.4.22.-:
pdb deposition date 2005-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 1yvbA00
1TLOA 3KKUA 3HHAA 3IHPA 4YYSA 2R9CA 3KX1A 2IBIA 5CVOB 1STFE 2P0RA 4W5CA 1AU0A 3IUTA 2AYNA 5A24A 2DZYA 1YVBA 3QT4A 1AU3A 3MTNA 2OZ2A 2E03A 3DF0A 2NQIA 2NQAA 2HH5A 1PCIA 3BWKA 1GCBA 2BDZA 4MSXA 4OEMA 1X9YA 2AVWA 3BPMA 4XR7A 1QDQA 2JQFR 4DMXA 1MIRA 4Q8GA 3H7DA 3O1GA 2XU1A 3WXEA 1IWDA 1O0EA 1AYUA 2YJ2A 3KFQA 3V6CA 2ACTA 4CZWA 1EWPA 3U8EA 2AS8A 3K9MA 2DCCA 4FIPA 4X6HA 1A6RA 1QOLA 4AXLA 1KXRA 4QBBA 1DF0A 4I04A 2F1GA 4WA6A 3OF8A 1EWOA 1KFXL 3C9EA 1BGOA 4P6GA 4RY2A 1Q6KA 2R9OA 3KW9A 1NB3A 1EF7A 1F2AA 1ICFA 1THEA 4BS5A 1PPPA 2G6DA 1F29A 1QXPA 2NQGA 1AIMA 2PADA 1AU4A 1KFUL 4W4UA 1NPZA 6PADA 4I07A 2CIOA 2DZZA 4YYWA 3IEJA 4N79A 2DJFB 3IMAA 2YJBA 1MEMA 4BPVA 3H6SA 1U9XA 3O0UA 3LFYA 1TL9A 3OVXA 4QH6A 4Q8HA 5EGWA 5CHTA 1AYWA 1GMYA 2B1MA 5FPWA 5CHVA 2FYEA 1ZCMA 1S4VA 2GHUA 2E02A 3MORA 4QRXA 3KWBX 2R9MA 3RVXA 4YV8A 1GLOA 4QRVA 3CBKA 8PCHA 1ME4A 1FH0A 5J94A 4QRGA 4PADA 5EF4A 1ITOA 2DCAA 3P5WA 2H7JA 3P5XA 2Y6EA 1MS6A 1ATKA 1AU2A 3PDFA 4CDFB 3OISA 4YYVA 3HHIA 1MHWA 1KHQA 3N3KA 2AUXA 1F2BA 4N8WA 1SP4B 4P6EA 2YJ9A 1MDWA 2F7DA 4AXMA 1K3BB 4BQVA 2R9NA 2XU5A 1U9VA 5PADA 2YJ8A 1BY8A 2AU1A 3H89A 1U5IA 3BC3A 2AUZA 2DC7A 1POPA 1JQPA 4KLBA 4XUIA 4OELA 1M6DA 3CH3X 7PCKA 2G7YA 3S3QA 2DC9A 4MZSA 2GFOA 3ERVA 4YVAA 4YYUA 1PE6A 1PADA 2VHSA 3I3TA 2E01A 3QSDA 2OP3A 3PW3A 1HUCB 2DC8A 2IPPB 2FUDA 3K24A 2FRAA 3HWNA 2PREA 3USVA 1SNKA 3OVZA 4CDEB 2FTDA 3B79A 5K16A 1NQCA 1QMYA 2Y5BA 3OF9A 3P5VA 4YYRA 1PPOA 3BCNA 3PNRA 4FK5A 3HD3A 1TU6A 4DMYA 3S3RA 1MEGA 3PBHA 3M99A 5CVNB 1BQIA 1Y08A 2FT2A 2ARYA 1YK8A 1CQDA 2DJGB 3CH2X 4PI3A 2WBFX 3H8CA 1CTEA 4CDCB 3QJ3A 1NLJA 2DC6A 4ZUXU 3H8BA 1PPDA 3K8UA 2FRQA 3TNXA 2XU3A 4I05A 3BPFA 1ME3A 2HXZA 3NHEA 3F5VA 4PP1A 4HWYA 3N3GA 1CSBB 2VHFA 1CPJA 1GECE 1U9QX 2B1NA 3F75A 1DEUA 3V6EA 2P7UA 1BP4A 2DCBA 4FJCA 3IOQA 2HD5A 4G54A 1PXVA 2P86A 2PNSA 2CB5A 1VJVA 2ATOA 1CS8A 3WXGA 3IV2A 2FO5A 2FQ9A 1YALA 4BSQA 3AI8A 3RVWA 5F02A 2PBHA 2C0YA 3GCBA 3I06A 1U9WA 1YK7A 1XKGA 2XU4A 1PIPA 3MHHA 1PPNA 3E1ZB 2O6XA 2YJCA 3D6SA 1YT7A 4MZOA 5JA7A 2AIMA 2BDLA 4CDDB 3P5UA 4BS6A 3KWZA 1CB5A 1NB5A 3N4CA 2E00A 4K7CA 4YYQA 3BOWA 1AYVA 1CVZA 1Y4HA 3CBJA 2G8EA 1CJLA 3KSEA 1F2CA 1EWLA 1NL6A 4W5BA 3RVVA 3LXSA 1VSNA 1PBHA 1CV8A 2R6NA 1KHPA 2R9FA 2HHNA 2G8JA 5JH3A 2DCDA 4X6IA 3ZUAA 4X6JA 3MHSA 3WXFA 2NQDB 2JQGR 5CVMA 1EWMA 4N4ZA 2AYOA 2OULA 9PAPA 1AECA 1ZIVA 4PP2E
chains in the Genus database with same CATH superfamily
1TLOA 5EZQA 3KKUA 3HHAA 3IHPA 4YYSA 2R9CA 3KX1A 2IBIA 5CVOB 1STFE 2P0RA 1DKIA 4W5CA 2DOSA 1AU0A 3IUTA 2AYNA 5A24A 2DZYA 1YVBA 3QT4A 1AU3A 1YZBA 3MTNA 2OZ2A 2E03A 3DF0A 2NQIA 2NQAA 4D8BA 2HH5A 1PCIA 3BWKA 1GCBA 1UKFA 2BDZA 4MSXA 4OEMA 1X9YA 4IUMA 2AVWA 3W30A 3BPMA 4XR7A 1QDQA 1PVJA 2JQFR 4DMXA 1MIRA 4Q8GA 3H7DA 3O1GA 2JRIA 3PHWA 2XU1A 4RF0A 3WXEA 1IWDA 1O0EA 1AYUA 2YJ2A 4D8EA 3KFQA 3V6CA 2ACTA 4CZWA 1EWPA 3U8EA 2AS8A 3K9MA 2DCCA 4FIPA 4X6HA 1A6RA 1QOLA 4AXLA 1KXRA 4QBBA 4A5UA 3PRPA 1DF0A 4I04A 2F1GA 3OQCA 4WA6A 3OF8A 1EWOA 2FE8A 4BOQA 4ZTBA 1KFXL 3C9EA 1BGOA 4P6GA 4RY2A 2HWKA 1Q6KA 2R9OA 3KW9A 1NB3A 1EF7A 1F2AA 1ICFA 1THEA 4BS5A 1PPPA 2G6DA 1F29A 1QXPA 2NQGA 3TMPA 1AIMA 5EZSA 2PADA 1AU4A 3BB7A 1KFUL 4W4UA 1NPZA 6PADA 3PSEA 4I07A 2CIOA 2DZZA 4YYWA 3IEJA 4N79A 2DJFB 3MP2A 3PHUA 3IMAA 2YJBA 3TRKA 4BOPA 1MEMA 4BPVA 3H6SA 1U9XA 3O0UA 3LFYA 1TL9A 4MM3B 3OVXA 4QH6A 4Q8HA 5EGWA 5CHTA 1AYWA 1GMYA 2B1MA 5FPWA 5CHVA 2FYEA 1ZCMA 1S4VA 2GHUA 3MTVA 3BBAA 4BOZA 2E02A 3MORA 4QRXA 3IFUA 3KWBX 2R9MA 3RVXA 4YV8A 1GLOA 4QRVA 3CBKA 8PCHA 1ME4A 1FH0A 5J94A 4QRGA 4PADA 5EF4A 1ITOA 2DCAA 4RKXA 3P5WA 2H7JA 3P5XA 2Y6EA 1MS6A 1ATKA 5JZEA 1AU2A 3PDFA 4CDFB 3OISA 4YYVA 3HHIA 4GUAA 1MHWA 3C0RA 1KHQA 3N3KA 2AUXA 1F2BA 4N8WA 5E6JA 1SP4B 4P6EA 2YJ9A 4OW0A 1MDWA 2F7DA 4AXMA 1K3BB 4BQVA 3O65A 4RNAA 2R9NA 2XU5A 1U9VA 5PADA 2YJ8A 1BY8A 2AU1A 3H89A 1U5IA 3BC3A 2AUZA 2DC7A 4XZXA 1POPA 1JQPA 4KLBA 4XUIA 4OELA 1M6DA 3CH3X 7PCKA 3BY4A 2G7YA 4REZA 3S3QA 2DC9A 3PRMA 4MZSA 4OVZA 2GFOA 2Z84A 3ERVA 4YVAA 4YYUA 1PE6A 1PADA 2VHSA 3I3TA 3RNVA 2E01A 2AGAA 3QSDA 2OP3A 3PW3A 1HUCB 2DC8A 2IPPB 2FUDA 3K24A 4R3DA 2FRAA 2JTCA 3HWNA 3B21A 2PREA 4IP3A 3USVA 1SNKA 3OVZA 4CDEB 2FTDA 3B79A 5K16A 1NQCA 5KO3A 4OVZB 1QMYA 2Y5BA 3OF9A 3P5VA 4YYRA 1PPOA 3BCNA 2BU3A 3PNRA 4FK5A 3HD3A 1TU6A 4DMYA 3S3RA 1MEGA 3PBHA 3M99A 5CVNB 1BQIA 1Y08A 2FT2A 2ARYA 1YK8A 1CQDA 2DJGB 3CH2X 4PI3A 2WBFX 3H8CA 4D8IA 1CTEA 4CDCB 3QJ3A 3W31A 1NLJA 3PHXA 2DC6A 4ZUXU 3H8BA 1PPDA 3K8UA 2FRQA 3TNXA 2XU3A 4I05A 3BPFA 3PT2A 1ME3A 4HXDB 2HXZA 4MI7A 3NHEA 3F5VA 4PP1A 4HWYA 3N3GA 1CSBB 2VHFA 1CPJA 1GECE 1U9QX 2B1NA 3F75A 1DEUA 3V6EA 2P7UA 1BP4A 2DCBA 4FJCA 3IOQA 4BOUA 2HD5A 2J7QA 4G54A 1PXVA 4M0WA 2P86A 2J7QC 2PNSA 2CB5A 1VJVA 4BOSA 2ATOA 1CS8A 3WXGA 3IV2A 2FO5A 2FQ9A 1YALA 4BSQA 3AI8A 4PT5A 3RVWA 2BTWA 5F02A 3MJ5A 2PBHA 2C0YA 3GCBA 3I06A 1U9WA 1YK7A 1XKGA 2XU4A 1PIPA 3MHHA 1PPNA 3E1ZB 2O6XA 2YJCA 3D6SA 2BTWB 1YT7A 2UZJA 4MZOA 5JA7A 2AIMA 2BDLA 4CDDB 3P5UA 4BS6A 4P16A 4RF1A 3KWZA 1CB5A 1NB5A 3N4CA 2E00A 4K7CA 4YYQA 3BOWA 1AYVA 1CVZA 1Y4HA 3CBJA 2G8EA 1CJLA 3KSEA 3ZNHA 1F2CA 1EWLA 1NL6A 4W5BA 3RVVA 4WURA 3LXSA 1VSNA 1PBHA 1CV8A 2R6NA 1KHPA 2R9FA 2HHNA 2G8JA 5JH3A 2DCDA 3E9SA 4X6IA 3ZUAA 4X6JA 3MHSA 3WXFA 2NQDB 2JQGR 5CVMA 1EWMA 4N4ZA 2AYOA 2OULA 9PAPA 1AECA 1ZIVA 4PP2E
chains in the Genus database with same CATH topology
1TLOA 3KKUA 3HHAA 3IHPA 4YYSA 2R9CA 3KX1A 2IBIA 5CVOB 1STFE 2P0RA 4W5CA 1AU0A 3IUTA 2AYNA 5A24A 2DZYA 1YVBA 4C5PA 3QT4A 1AU3A 1W5RA 3MTNA 2OZ2A 2E03A 3DF0A 2NQIA 2NQAA 2HH5A 1PCIA 3BWKA 1GCBA 2BDZA 4MSXA 4OEMA 1X9YA 2AVWA 3BPMA 4XR7A 1QDQA 2JQFR 4DMXA 1MIRA 4Q8GA 3H7DA 3O1GA 2XU1A 3WXEA 1IWDA 1O0EA 1AYUA 2YJ2A 3KFQA 3V6CA 2ACTA 4CZWA 1EWPA 3U8EA 2AS8A 3K9MA 2DCCA 4FIPA 4X6HA 1A6RA 1QOLA 4AXLA 1W6FA 1KXRA 4QBBA 1DF0A 4I04A 2F1GA 4WA6A 3OF8A 1EWOA 1GX3A 1KFXL 3C9EA 1BGOA 4B55A 4P6GA 4RY2A 1Q6KA 2R9OA 3KW9A 1NB3A 1EF7A 1F2AA 1ICFA 1THEA 4BS5A 1PPPA 2G6DA 1F29A 1QXPA 2NQGA 1AIMA 2PADA 1AU4A 1KFUL 4W4UA 1NPZA 6PADA 4I07A 2CIOA 2DZZA 4YYWA 3IEJA 4N79A 2DJFB 3IMAA 2YJBA 1MEMA 4BPVA 3H6SA 1U9XA 3O0UA 3LFYA 1TL9A 3OVXA 4QH6A 2VFBA 4Q8HA 5EGWA 5CHTA 1AYWA 1GMYA 2B1MA 5FPWA 5CHVA 2FYEA 1ZCMA 1S4VA 2GHUA 2E02A 3MORA 4QRXA 3KWBX 2R9MA 3RVXA 4YV8A 1GLOA 4QRVA 3CBKA 8PCHA 1ME4A 1FH0A 5J94A 4QRGA 4PADA 5EF4A 1ITOA 2DCAA 3P5WA 2H7JA 3P5XA 2Y6EA 1MS6A 1ATKA 1AU2A 3PDFA 4CDFB 3OISA 4YYVA 3HHIA 1MHWA 1KHQA 3N3KA 2AUXA 1F2BA 4N8WA 1SP4B 4P6EA 2BSZA 2YJ9A 1MDWA 2F7DA 4AXMA 1K3BB 4BQVA 2R9NA 2XU5A 1U9VA 5PADA 2YJ8A 1BY8A 2AU1A 3H89A 1U5IA 3BC3A 2AUZA 2DC7A 1POPA 3LTWA 1JQPA 4KLBA 4XUIA 4OELA 1M6DA 3CH3X 7PCKA 2G7YA 3S3QA 2DC9A 4MZSA 2GFOA 3ERVA 4YVAA 4YYUA 1PE6A 1PADA 2VHSA 3I3TA 2E01A 3QSDA 2OP3A 3PW3A 1HUCB 2DC8A 2IPPB 2FUDA 3K24A 2VFCA 2FRAA 3HWNA 2PREA 3USVA 1SNKA 3OVZA 4CDEB 2FTDA 3B79A 5K16A 1NQCA 4GUZA 1QMYA 2Y5BA 3OF9A 3P5VA 4YYRA 1PPOA 3BCNA 3PNRA 4FK5A 3HD3A 1TU6A 4DMYA 4NV8A 3S3RA 1MEGA 3PBHA 3M99A 5CVNB 1BQIA 1Y08A 2FT2A 2ARYA 1YK8A 1CQDA 3D9WA 1E2TA 2DJGB 3CH2X 4PI3A 2WBFX 3H8CA 1CTEA 4CDCB 3QJ3A 1NLJA 2DC6A 4ZUXU 3H8BA 1PPDA 3K8UA 2FRQA 3TNXA 2XU3A 4I05A 3BPFA 1ME3A 2HXZA 3NHEA 3F5VA 4PP1A 4HWYA 3N3GA 1CSBB 2VHFA 1CPJA 1GECE 1U9QX 2B1NA 3F75A 1DEUA 3V6EA 2P7UA 1BP4A 2DCBA 4NV7A 4FJCA 3IOQA 2HD5A 4G54A 1PXVA 2P86A 4BGFA 2PNSA 2CB5A 1VJVA 2ATOA 1CS8A 3WXGA 3IV2A 2FO5A 2FQ9A 1W4TA 1YALA 4BSQA 3AI8A 3RVWA 5F02A 2PBHA 2C0YA 3GCBA 3I06A 1U9WA 1YK7A 1XKGA 2XU4A 1PIPA 3MHHA 1PPNA 3E1ZB 2O6XA 2YJCA 3D6SA 1YT7A 4MZOA 5JA7A 2AIMA 2BDLA 4CDDB 3P5UA 4BS6A 3KWZA 1CB5A 1NB5A 3N4CA 2E00A 4K7CA 4YYQA 3BOWA 1AYVA 1CVZA 1Y4HA 3CBJA 2G8EA 1CJLA 3KSEA 1F2CA 1EWLA 1NL6A 4W5BA 3RVVA 3LXSA 1VSNA 1PBHA 1CV8A 2R6NA 1KHPA 2R9FA 2HHNA 2G8JA 5JH3A 2DCDA 4X6IA 3ZUAA 4X6JA 3MHSA 3WXFA 2NQDB 2JQGR 5CVMA 1EWMA 4N4ZA 2AYOA 2OULA 9PAPA 1AECA 1ZIVA 4PP2E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TLO A;  3KKU A;  3HHA A;  3IHP A;  4YYS A;  2R9C A;  3KX1 A;  2IBI A;  5CVO B;  1STF E;  2P0R A;  4W5C A;  1AU0 A;  3IUT A;  2AYN A;  5A24 A;  2DZY A;  1YVB A;  3QT4 A;  1AU3 A;  3MTN A;  2OZ2 A;  2E03 A;  3DF0 A;  2NQI A;  2NQA A;  2HH5 A;  1PCI A;  3BWK A;  1GCB A;  2BDZ A;  4MSX A;  4OEM A;  1X9Y A;  2AVW A;  3BPM A;  4XR7 A;  1QDQ A;  2JQF R;  4DMX A;  1MIR A;  4Q8G A;  3H7D A;  3O1G A;  2XU1 A;  3WXE A;  1IWD A;  1O0E A;  1AYU A;  2YJ2 A;  3KFQ A;  3V6C A;  2ACT A;  4CZW A;  1EWP A;  3U8E A;  2AS8 A;  3K9M A;  2DCC A;  4FIP A;  4X6H A;  1A6R A;  1QOL A;  4AXL A;  1KXR A;  4QBB A;  1DF0 A;  4I04 A;  2F1G A;  4WA6 A;  3OF8 A;  1EWO A;  1KFX L;  3C9E A;  1BGO A;  4P6G A;  4RY2 A;  1Q6K A;  2R9O A;  3KW9 A;  1NB3 A;  1EF7 A;  1F2A A;  1ICF A;  1THE A;  4BS5 A;  1PPP A;  2G6D A;  1F29 A;  1QXP A;  2NQG A;  1AIM A;  2PAD A;  1AU4 A;  1KFU L;  4W4U A;  1NPZ A;  6PAD A;  4I07 A;  2CIO A;  2DZZ A;  4YYW A;  3IEJ A;  4N79 A;  2DJF B;  3IMA A;  2YJB A;  1MEM A;  4BPV A;  3H6S A;  1U9X A;  3O0U A;  3LFY A;  1TL9 A;  3OVX A;  4QH6 A;  4Q8H A;  5EGW A;  5CHT A;  1AYW A;  1GMY A;  2B1M A;  5FPW A;  5CHV A;  2FYE A;  1ZCM A;  1S4V A;  2GHU A;  2E02 A;  3MOR A;  4QRX A;  3KWB X;  2R9M A;  3RVX A;  4YV8 A;  1GLO A;  4QRV A;  3CBK A;  8PCH A;  1ME4 A;  1FH0 A;  5J94 A;  4QRG A;  4PAD A;  5EF4 A;  1ITO A;  2DCA A;  3P5W A;  2H7J A;  3P5X A;  2Y6E A;  1MS6 A;  1ATK A;  1AU2 A;  3PDF A;  4CDF B;  3OIS A;  4YYV A;  3HHI A;  1MHW A;  1KHQ A;  3N3K A;  2AUX A;  1F2B A;  4N8W A;  1SP4 B;  4P6E A;  2YJ9 A;  1MDW A;  2F7D A;  4AXM A;  1K3B B;  4BQV A;  2R9N A;  2XU5 A;  1U9V A;  5PAD A;  2YJ8 A;  1BY8 A;  2AU1 A;  3H89 A;  1U5I A;  3BC3 A;  2AUZ A;  2DC7 A;  1POP A;  1JQP A;  4KLB A;  4XUI A;  4OEL A;  1M6D A;  3CH3 X;  7PCK A;  2G7Y A;  3S3Q A;  2DC9 A;  4MZS A;  2GFO A;  3ERV A;  4YVA A;  4YYU A;  1PE6 A;  1PAD A;  2VHS A;  3I3T A;  2E01 A;  3QSD A;  2OP3 A;  3PW3 A;  1HUC B;  2DC8 A;  2IPP B;  2FUD A;  3K24 A;  2FRA A;  3HWN A;  2PRE A;  3USV A;  1SNK A;  3OVZ A;  4CDE B;  2FTD A;  3B79 A;  5K16 A;  1NQC A;  1QMY A;  2Y5B A;  3OF9 A;  3P5V A;  4YYR A;  1PPO A;  3BCN A;  3PNR A;  4FK5 A;  3HD3 A;  1TU6 A;  4DMY A;  3S3R A;  1MEG A;  3PBH A;  3M99 A;  5CVN B;  1BQI A;  1Y08 A;  2FT2 A;  2ARY A;  1YK8 A;  1CQD A;  2DJG B;  3CH2 X;  4PI3 A;  2WBF X;  3H8C A;  1CTE A;  4CDC B;  3QJ3 A;  1NLJ A;  2DC6 A;  4ZUX U;  3H8B A;  1PPD A;  3K8U A;  2FRQ A;  3TNX A;  2XU3 A;  4I05 A;  3BPF A;  1ME3 A;  2HXZ A;  3NHE A;  3F5V A;  4PP1 A;  4HWY A;  3N3G A;  1CSB B;  2VHF A;  1CPJ A;  1GEC E;  1U9Q X;  2B1N A;  3F75 A;  1DEU A;  3V6E A;  2P7U A;  1BP4 A;  2DCB A;  4FJC A;  3IOQ A;  2HD5 A;  4G54 A;  1PXV A;  2P86 A;  2PNS A;  2CB5 A;  1VJV A;  2ATO A;  1CS8 A;  3WXG A;  3IV2 A;  2FO5 A;  2FQ9 A;  1YAL A;  4BSQ A;  3AI8 A;  3RVW A;  5F02 A;  2PBH A;  2C0Y A;  3GCB A;  3I06 A;  1U9W A;  1YK7 A;  1XKG A;  2XU4 A;  1PIP A;  3MHH A;  1PPN A;  3E1Z B;  2O6X A;  2YJC A;  3D6S A;  1YT7 A;  4MZO A;  5JA7 A;  2AIM A;  2BDL A;  4CDD B;  3P5U A;  4BS6 A;  3KWZ A;  1CB5 A;  1NB5 A;  3N4C A;  2E00 A;  4K7C A;  4YYQ A;  3BOW A;  1AYV A;  1CVZ A;  1Y4H A;  3CBJ A;  2G8E A;  1CJL A;  3KSE A;  1F2C A;  1EWL A;  1NL6 A;  4W5B A;  3RVV A;  3LXS A;  1VSN A;  1PBH A;  1CV8 A;  2R6N A;  1KHP A;  2R9F A;  2HHN A;  2G8J A;  5JH3 A;  2DCD A;  4X6I A;  3ZUA A;  4X6J A;  3MHS A;  3WXF A;  2NQD B;  2JQG R;  5CVM A;  1EWM A;  4N4Z A;  2AYO A;  2OUL A;  9PAP A;  1AEC A;  1ZIV A;  4PP2 E; 
#chains in the Genus database with same CATH topology
 1TLO A;  5EZQ A;  3KKU A;  3HHA A;  3IHP A;  4YYS A;  2R9C A;  3KX1 A;  2IBI A;  5CVO B;  1STF E;  2P0R A;  1DKI A;  4W5C A;  2DOS A;  1AU0 A;  3IUT A;  2AYN A;  5A24 A;  2DZY A;  1YVB A;  3QT4 A;  1AU3 A;  1YZB A;  3MTN A;  2OZ2 A;  2E03 A;  3DF0 A;  2NQI A;  2NQA A;  4D8B A;  2HH5 A;  1PCI A;  3BWK A;  1GCB A;  1UKF A;  2BDZ A;  4MSX A;  4OEM A;  1X9Y A;  4IUM A;  2AVW A;  3W30 A;  3BPM A;  4XR7 A;  1QDQ A;  1PVJ A;  2JQF R;  4DMX A;  1MIR A;  4Q8G A;  3H7D A;  3O1G A;  2JRI A;  3PHW A;  2XU1 A;  4RF0 A;  3WXE A;  1IWD A;  1O0E A;  1AYU A;  2YJ2 A;  4D8E A;  3KFQ A;  3V6C A;  2ACT A;  4CZW A;  1EWP A;  3U8E A;  2AS8 A;  3K9M A;  2DCC A;  4FIP A;  4X6H A;  1A6R A;  1QOL A;  4AXL A;  1KXR A;  4QBB A;  4A5U A;  3PRP A;  1DF0 A;  4I04 A;  2F1G A;  3OQC A;  4WA6 A;  3OF8 A;  1EWO A;  2FE8 A;  4BOQ A;  4ZTB A;  1KFX L;  3C9E A;  1BGO A;  4P6G A;  4RY2 A;  2HWK A;  1Q6K A;  2R9O A;  3KW9 A;  1NB3 A;  1EF7 A;  1F2A A;  1ICF A;  1THE A;  4BS5 A;  1PPP A;  2G6D A;  1F29 A;  1QXP A;  2NQG A;  3TMP A;  1AIM A;  5EZS A;  2PAD A;  1AU4 A;  3BB7 A;  1KFU L;  4W4U A;  1NPZ A;  6PAD A;  3PSE A;  4I07 A;  2CIO A;  2DZZ A;  4YYW A;  3IEJ A;  4N79 A;  2DJF B;  3MP2 A;  3PHU A;  3IMA A;  2YJB A;  3TRK A;  4BOP A;  1MEM A;  4BPV A;  3H6S A;  1U9X A;  3O0U A;  3LFY A;  1TL9 A;  4MM3 B;  3OVX A;  4QH6 A;  4Q8H A;  5EGW A;  5CHT A;  1AYW A;  1GMY A;  2B1M A;  5FPW A;  5CHV A;  2FYE A;  1ZCM A;  1S4V A;  2GHU A;  3MTV A;  3BBA A;  4BOZ A;  2E02 A;  3MOR A;  4QRX A;  3IFU A;  3KWB X;  2R9M A;  3RVX A;  4YV8 A;  1GLO A;  4QRV A;  3CBK A;  8PCH A;  1ME4 A;  1FH0 A;  5J94 A;  4QRG A;  4PAD A;  5EF4 A;  1ITO A;  2DCA A;  4RKX A;  3P5W A;  2H7J A;  3P5X A;  2Y6E A;  1MS6 A;  1ATK A;  5JZE A;  1AU2 A;  3PDF A;  4CDF B;  3OIS A;  4YYV A;  3HHI A;  4GUA A;  1MHW A;  3C0R A;  1KHQ A;  3N3K A;  2AUX A;  1F2B A;  4N8W A;  5E6J A;  1SP4 B;  4P6E A;  2YJ9 A;  4OW0 A;  1MDW A;  2F7D A;  4AXM A;  1K3B B;  4BQV A;  3O65 A;  4RNA A;  2R9N A;  2XU5 A;  1U9V A;  5PAD A;  2YJ8 A;  1BY8 A;  2AU1 A;  3H89 A;  1U5I A;  3BC3 A;  2AUZ A;  2DC7 A;  4XZX A;  1POP A;  1JQP A;  4KLB A;  4XUI A;  4OEL A;  1M6D A;  3CH3 X;  7PCK A;  3BY4 A;  2G7Y A;  4REZ A;  3S3Q A;  2DC9 A;  3PRM A;  4MZS A;  4OVZ A;  2GFO A;  2Z84 A;  3ERV A;  4YVA A;  4YYU A;  1PE6 A;  1PAD A;  2VHS A;  3I3T A;  3RNV A;  2E01 A;  2AGA A;  3QSD A;  2OP3 A;  3PW3 A;  1HUC B;  2DC8 A;  2IPP B;  2FUD A;  3K24 A;  4R3D A;  2FRA A;  2JTC A;  3HWN A;  3B21 A;  2PRE A;  4IP3 A;  3USV A;  1SNK A;  3OVZ A;  4CDE B;  2FTD A;  3B79 A;  5K16 A;  1NQC A;  5KO3 A;  4OVZ B;  1QMY A;  2Y5B A;  3OF9 A;  3P5V A;  4YYR A;  1PPO A;  3BCN A;  2BU3 A;  3PNR A;  4FK5 A;  3HD3 A;  1TU6 A;  4DMY A;  3S3R A;  1MEG A;  3PBH A;  3M99 A;  5CVN B;  1BQI A;  1Y08 A;  2FT2 A;  2ARY A;  1YK8 A;  1CQD A;  2DJG B;  3CH2 X;  4PI3 A;  2WBF X;  3H8C A;  4D8I A;  1CTE A;  4CDC B;  3QJ3 A;  3W31 A;  1NLJ A;  3PHX A;  2DC6 A;  4ZUX U;  3H8B A;  1PPD A;  3K8U A;  2FRQ A;  3TNX A;  2XU3 A;  4I05 A;  3BPF A;  3PT2 A;  1ME3 A;  4HXD B;  2HXZ A;  4MI7 A;  3NHE A;  3F5V A;  4PP1 A;  4HWY A;  3N3G A;  1CSB B;  2VHF A;  1CPJ A;  1GEC E;  1U9Q X;  2B1N A;  3F75 A;  1DEU A;  3V6E A;  2P7U A;  1BP4 A;  2DCB A;  4FJC A;  3IOQ A;  4BOU A;  2HD5 A;  2J7Q A;  4G54 A;  1PXV A;  4M0W A;  2P86 A;  2J7Q C;  2PNS A;  2CB5 A;  1VJV A;  4BOS A;  2ATO A;  1CS8 A;  3WXG A;  3IV2 A;  2FO5 A;  2FQ9 A;  1YAL A;  4BSQ A;  3AI8 A;  4PT5 A;  3RVW A;  2BTW A;  5F02 A;  3MJ5 A;  2PBH A;  2C0Y A;  3GCB A;  3I06 A;  1U9W A;  1YK7 A;  1XKG A;  2XU4 A;  1PIP A;  3MHH A;  1PPN A;  3E1Z B;  2O6X A;  2YJC A;  3D6S A;  2BTW B;  1YT7 A;  2UZJ A;  4MZO A;  5JA7 A;  2AIM A;  2BDL A;  4CDD B;  3P5U A;  4BS6 A;  4P16 A;  4RF1 A;  3KWZ A;  1CB5 A;  1NB5 A;  3N4C A;  2E00 A;  4K7C A;  4YYQ A;  3BOW A;  1AYV A;  1CVZ A;  1Y4H A;  3CBJ A;  2G8E A;  1CJL A;  3KSE A;  3ZNH A;  1F2C A;  1EWL A;  1NL6 A;  4W5B A;  3RVV A;  4WUR A;  3LXS A;  1VSN A;  1PBH A;  1CV8 A;  2R6N A;  1KHP A;  2R9F A;  2HHN A;  2G8J A;  5JH3 A;  2DCD A;  3E9S A;  4X6I A;  3ZUA A;  4X6J A;  3MHS A;  3WXF A;  2NQD B;  2JQG R;  5CVM A;  1EWM A;  4N4Z A;  2AYO A;  2OUL A;  9PAP A;  1AEC A;  1ZIV A;  4PP2 E; 
#chains in the Genus database with same CATH homology
 1TLO A;  3KKU A;  3HHA A;  3IHP A;  4YYS A;  2R9C A;  3KX1 A;  2IBI A;  5CVO B;  1STF E;  2P0R A;  4W5C A;  1AU0 A;  3IUT A;  2AYN A;  5A24 A;  2DZY A;  1YVB A;  4C5P A;  3QT4 A;  1AU3 A;  1W5R A;  3MTN A;  2OZ2 A;  2E03 A;  3DF0 A;  2NQI A;  2NQA A;  2HH5 A;  1PCI A;  3BWK A;  1GCB A;  2BDZ A;  4MSX A;  4OEM A;  1X9Y A;  2AVW A;  3BPM A;  4XR7 A;  1QDQ A;  2JQF R;  4DMX A;  1MIR A;  4Q8G A;  3H7D A;  3O1G A;  2XU1 A;  3WXE A;  1IWD A;  1O0E A;  1AYU A;  2YJ2 A;  3KFQ A;  3V6C A;  2ACT A;  4CZW A;  1EWP A;  3U8E A;  2AS8 A;  3K9M A;  2DCC A;  4FIP A;  4X6H A;  1A6R A;  1QOL A;  4AXL A;  1W6F A;  1KXR A;  4QBB A;  1DF0 A;  4I04 A;  2F1G A;  4WA6 A;  3OF8 A;  1EWO A;  1GX3 A;  1KFX L;  3C9E A;  1BGO A;  4B55 A;  4P6G A;  4RY2 A;  1Q6K A;  2R9O A;  3KW9 A;  1NB3 A;  1EF7 A;  1F2A A;  1ICF A;  1THE A;  4BS5 A;  1PPP A;  2G6D A;  1F29 A;  1QXP A;  2NQG A;  1AIM A;  2PAD A;  1AU4 A;  1KFU L;  4W4U A;  1NPZ A;  6PAD A;  4I07 A;  2CIO A;  2DZZ A;  4YYW A;  3IEJ A;  4N79 A;  2DJF B;  3IMA A;  2YJB A;  1MEM A;  4BPV A;  3H6S A;  1U9X A;  3O0U A;  3LFY A;  1TL9 A;  3OVX A;  4QH6 A;  2VFB A;  4Q8H A;  5EGW A;  5CHT A;  1AYW A;  1GMY A;  2B1M A;  5FPW A;  5CHV A;  2FYE A;  1ZCM A;  1S4V A;  2GHU A;  2E02 A;  3MOR A;  4QRX A;  3KWB X;  2R9M A;  3RVX A;  4YV8 A;  1GLO A;  4QRV A;  3CBK A;  8PCH A;  1ME4 A;  1FH0 A;  5J94 A;  4QRG A;  4PAD A;  5EF4 A;  1ITO A;  2DCA A;  3P5W A;  2H7J A;  3P5X A;  2Y6E A;  1MS6 A;  1ATK A;  1AU2 A;  3PDF A;  4CDF B;  3OIS A;  4YYV A;  3HHI A;  1MHW A;  1KHQ A;  3N3K A;  2AUX A;  1F2B A;  4N8W A;  1SP4 B;  4P6E A;  2BSZ A;  2YJ9 A;  1MDW A;  2F7D A;  4AXM A;  1K3B B;  4BQV A;  2R9N A;  2XU5 A;  1U9V A;  5PAD A;  2YJ8 A;  1BY8 A;  2AU1 A;  3H89 A;  1U5I A;  3BC3 A;  2AUZ A;  2DC7 A;  1POP A;  3LTW A;  1JQP A;  4KLB A;  4XUI A;  4OEL A;  1M6D A;  3CH3 X;  7PCK A;  2G7Y A;  3S3Q A;  2DC9 A;  4MZS A;  2GFO A;  3ERV A;  4YVA A;  4YYU A;  1PE6 A;  1PAD A;  2VHS A;  3I3T A;  2E01 A;  3QSD A;  2OP3 A;  3PW3 A;  1HUC B;  2DC8 A;  2IPP B;  2FUD A;  3K24 A;  2VFC A;  2FRA A;  3HWN A;  2PRE A;  3USV A;  1SNK A;  3OVZ A;  4CDE B;  2FTD A;  3B79 A;  5K16 A;  1NQC A;  4GUZ A;  1QMY A;  2Y5B A;  3OF9 A;  3P5V A;  4YYR A;  1PPO A;  3BCN A;  3PNR A;  4FK5 A;  3HD3 A;  1TU6 A;  4DMY A;  4NV8 A;  3S3R A;  1MEG A;  3PBH A;  3M99 A;  5CVN B;  1BQI A;  1Y08 A;  2FT2 A;  2ARY A;  1YK8 A;  1CQD A;  3D9W A;  1E2T A;  2DJG B;  3CH2 X;  4PI3 A;  2WBF X;  3H8C A;  1CTE A;  4CDC B;  3QJ3 A;  1NLJ A;  2DC6 A;  4ZUX U;  3H8B A;  1PPD A;  3K8U A;  2FRQ A;  3TNX A;  2XU3 A;  4I05 A;  3BPF A;  1ME3 A;  2HXZ A;  3NHE A;  3F5V A;  4PP1 A;  4HWY A;  3N3G A;  1CSB B;  2VHF A;  1CPJ A;  1GEC E;  1U9Q X;  2B1N A;  3F75 A;  1DEU A;  3V6E A;  2P7U A;  1BP4 A;  2DCB A;  4NV7 A;  4FJC A;  3IOQ A;  2HD5 A;  4G54 A;  1PXV A;  2P86 A;  4BGF A;  2PNS A;  2CB5 A;  1VJV A;  2ATO A;  1CS8 A;  3WXG A;  3IV2 A;  2FO5 A;  2FQ9 A;  1W4T A;  1YAL A;  4BSQ A;  3AI8 A;  3RVW A;  5F02 A;  2PBH A;  2C0Y A;  3GCB A;  3I06 A;  1U9W A;  1YK7 A;  1XKG A;  2XU4 A;  1PIP A;  3MHH A;  1PPN A;  3E1Z B;  2O6X A;  2YJC A;  3D6S A;  1YT7 A;  4MZO A;  5JA7 A;  2AIM A;  2BDL A;  4CDD B;  3P5U A;  4BS6 A;  3KWZ A;  1CB5 A;  1NB5 A;  3N4C A;  2E00 A;  4K7C A;  4YYQ A;  3BOW A;  1AYV A;  1CVZ A;  1Y4H A;  3CBJ A;  2G8E A;  1CJL A;  3KSE A;  1F2C A;  1EWL A;  1NL6 A;  4W5B A;  3RVV A;  3LXS A;  1VSN A;  1PBH A;  1CV8 A;  2R6N A;  1KHP A;  2R9F A;  2HHN A;  2G8J A;  5JH3 A;  2DCD A;  4X6I A;  3ZUA A;  4X6J A;  3MHS A;  3WXF A;  2NQD B;  2JQG R;  5CVM A;  1EWM A;  4N4Z A;  2AYO A;  2OUL A;  9PAP A;  1AEC A;  1ZIV A;  4PP2 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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