2ARYA

Catalytic domain of human calpain-1
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Calpain-1 catalytic subunit
total genus 89
structure length 322
sequence length 322
chains with identical sequence B
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2005-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2aryA02
2DC7A 3IOQA 4BS6A 2AYOA 2E03A 3D6SA 1ICFA 3I3TA 2P86A 3H6SA 4KLBA 4XUIA 2PADA 2G8JA 1AU4A 2B1NA 4QBBA 1DF0A 4QH6A 3O0UA 4PI3A 4X6JA 3AI8A 1CVZA 2BDZA 2OZ2A 1NQCA 4I04A 2DZYA 4YYVA 1QMYA 3PDFA 3IHPA 2DCBA 3BPMA 2XU1A 2F7DA 1GMYA 2OULA 3CH2X 3BWKA 2HHNA 1GCBA 1F29A 4DMYA 1K3BB 3CH3X 3OVXA 1F2CA 4AXMA 4CDDB 1CPJA 1GECE 3QT4A 3KWBX 3CBJA 3H8CA 2YJCA 4CDEB 2DC6A 3ERVA 2R9MA 1STFE 2ATOA 1EWPA 4MZSA 2Y6EA 4RY2A 3USVA 4YVAA 2OP3A 2R9OA 9PAPA 4Q8HA 1SNKA 3V6CA 3RVXA 4W5BA 1F2AA 5JH3A 5K16A 3H7DA 4K7CA 1ATKA 3E1ZB 2NQGA 1ZCMA 2P0RA 1NB5A 1ITOA 5CVOB 1M6DA 1AU2A 1AECA 1A6RA 1QXPA 1AU0A 2E00A 2DZZA 2PBHA 5EF4A 5CVMA 3OISA 4N4ZA 1KFXL 4PP2E 4N79A 1SP4B 3HWNA 2DC9A 1CTEA 2DCAA 1KHPA 1NPZA 1EWLA 4YYSA 3O1GA 1BY8A 1PCIA 2FT2A 1AU3A 3IV2A 3KKUA 3MORA 1PPDA 2FRAA 1ME4A 2G6DA 5CVNB 2YJBA 1U9XA 2XU4A 2GFOA 1NLJA 3N3KA 2E01A 2WBFX 1QOLA 1CS8A 4XR7A 1MS6A 3HHAA 4BPVA 1BQIA 4YYRA 1YVBA 3P5WA 5PADA 1MEGA 2AVWA 4QRVA 2FTDA 3WXEA 2FO5A 1EF7A 3MHSA 2P7UA 4DMXA 1FH0A 3KWZA 3KFQA 5JA7A 4W5CA 1U5IA 2YJ2A 3KW9A 2AS8A 4PP1A 1KHQA 2JQFR 1PPPA 1CV8A 3LFYA 3F5VA 4BSQA 1THEA 2GHUA 1MDWA 3ZUAA 2C0YA 3BC3A 1JQPA 2AUZA 3B79A 2FYEA 4X6HA 5FPWA 2DCCA 3S3QA 4FJCA 4QRGA 3PBHA 4HWYA 4CZWA 1NL6A 3OVZA 2FQ9A 3P5VA 4CDCB 2G8EA 1ZIVA 1PPNA 3RVVA 2VHSA 2ARYA 3LXSA 7PCKA 2AUXA 1YT7A 3MHHA 2R9CA 2XU3A 2DC8A 1U9QX 2NQAA 4Q8GA 4BS5A 4OELA 4CDFB 2JQGR 2R6NA 2R9NA 3BOWA 2BDLA 2CIOA 3TNXA 4WA6A 5EGWA 1PE6A 1VJVA 1KXRA 2PREA 4YV8A 4X6IA 2FUDA 4FK5A 3WXGA 6PADA 3OF8A 2FRQA 2NQIA 1PBHA 2DJFB 3N4CA 2Y5BA 1HUCB 2HXZA 1QDQA 5CHVA 3HHIA 2H7JA 3IUTA 1YK7A 1CJLA 4I05A 5A24A 2O6XA 2E02A 4QRXA 1VSNA 1MEMA 4MZOA 4W4UA 3C9EA 1BP4A 3DF0A 1DEUA 3QJ3A 1PADA 2IBIA 3H89A 3PW3A 1TU6A 3WXFA 1AIMA 2AU1A 4P6GA 4N8WA 1CB5A 4FIPA 2DCDA 3MTNA 4YYWA 4YYUA 4ZUXU 3BCNA 3CBKA 1CQDA 1XKGA 1O0EA 1PIPA 3M99A 1U9WA 3KX1A 2AIMA 1IWDA 3K8UA 8PCHA 3OF9A 3K24A 1POPA 1S4VA 3F75A 2HH5A 4YYQA 3KSEA 4BQVA 5J94A 1GLOA 3I06A 2R9FA 2CB5A 3S3RA 1BGOA 1TLOA 1EWOA 5F02A 1ME3A 1Q6KA 4P6EA 2F1GA 1Y4HA 2VHFA 1AYUA 1YK8A 3N3GA 2PNSA 2YJ8A 2XU5A 1MHWA 4I07A 3NHEA 1AYVA 1EWMA 1PPOA 1U9VA 1NB3A 2IPPB 4MSXA 3GCBA 5CHTA 1CSBB 1F2BA 3HD3A 3IEJA 3P5UA 3V6EA 1YALA 2AYNA 2NQDB 3IMAA 3PNRA 3H8BA 1MIRA 2DJGB 1AYWA 1X9YA 4AXLA 3QSDA 2ACTA 3P5XA 1PXVA 2YJ9A 2G7YA 1Y08A 3K9MA 4G54A 2HD5A 1TL9A 4PADA 3U8EA 3BPFA 1KFUL 2B1MA 4OEMA 3RVWA
chains in the Genus database with same CATH superfamily
2DC7A 3IOQA 4BS6A 2AYOA 2E03A 3D6SA 3BY4A 1ICFA 3I3TA 4ZTBA 2BTWB 2P86A 3H6SA 3C0RA 4KLBA 4XUIA 2PADA 2G8JA 1AU4A 2B1NA 4QBBA 1DF0A 3IFUA 4QH6A 2FE8A 3O0UA 3BB7A 4PI3A 3B21A 4X6JA 3AI8A 1CVZA 2BDZA 2OZ2A 1NQCA 4I04A 2DZYA 4P16A 4YYVA 5E6JA 1QMYA 3PDFA 2DCBA 3BPMA 2XU1A 2F7DA 1GMYA 2OULA 3CH2X 3BWKA 2HHNA 1GCBA 1F29A 4DMYA 1K3BB 3CH3X 3OVXA 1F2CA 4AXMA 4CDDB 1CPJA 1GECE 3ZNHA 3QT4A 3KWBX 3CBJA 3H8CA 2YJCA 4CDEB 2DC6A 3ERVA 2R9MA 1STFE 2ATOA 1EWPA 4MZSA 5EZQA 2Y6EA 4RY2A 3USVA 4YVAA 2OP3A 2R9OA 9PAPA 4D8BA 4Q8HA 1SNKA 4IUMA 3V6CA 4RKXA 3RVXA 4W5BA 2HWKA 1F2AA 5JH3A 5K16A 3PRMA 3H7DA 4K7CA 1ATKA 4OVZA 3E1ZB 2NQGA 1ZCMA 2P0RA 4RF1A 1NB5A 1ITOA 5CVOB 2Z84A 1M6DA 1AU2A 1AECA 3PRPA 1A6RA 1QXPA 1AU0A 2E00A 2DZZA 2PBHA 5EF4A 2AGAA 5CVMA 3OISA 4N4ZA 1KFXL 2BTWA 4PP2E 4N79A 1SP4B 3HWNA 2DC9A 1CTEA 2DCAA 1KHPA 1NPZA 1EWLA 4YYSA 3O1GA 3PHXA 1BY8A 3W31A 1PCIA 2FT2A 1AU3A 3IV2A 3KKUA 3MORA 1PPDA 2FRAA 1ME4A 2G6DA 5CVNB 1YZBA 2YJBA 1U9XA 2XU4A 2GFOA 1NLJA 3O65A 2DOSA 4BOQA 3N3KA 2E01A 2WBFX 1QOLA 1CS8A 4XR7A 1MS6A 3HHAA 4WURA 4BPVA 1BQIA 4YYRA 1YVBA 3P5WA 5EZSA 5PADA 1MEGA 2AVWA 4QRVA 2FTDA 3WXEA 2FO5A 1EF7A 3MHSA 2P7UA 4XZXA 4DMXA 1FH0A 3KWZA 3KFQA 5JA7A 4W5CA 1U5IA 2YJ2A 3KW9A 3MJ5A 2AS8A 4PP1A 1KHQA 2JQFR 5JZEA 1PPPA 1CV8A 3LFYA 3F5VA 4BSQA 1THEA 2GHUA 4BOZA 1MDWA 3ZUAA 2C0YA 3BC3A 1JQPA 2AUZA 3B79A 2FYEA 4X6HA 5FPWA 4RNAA 2DCCA 4A5UA 4M0WA 3S3QA 2UZJA 4FJCA 4QRGA 4REZA 3PBHA 4HWYA 4CZWA 1NL6A 3OVZA 2FQ9A 3P5VA 4CDCB 2G8EA 1ZIVA 1PPNA 3RVVA 4PT5A 2VHSA 2ARYA 3LXSA 3PSEA 7PCKA 2AUXA 1YT7A 3MHHA 2R9CA 2XU3A 2DC8A 1U9QX 2NQAA 4Q8GA 4BS5A 3OQCA 4OELA 4CDFB 3PHUA 2JQGR 2R6NA 2R9NA 3BOWA 3RNVA 2BDLA 2CIOA 3TNXA 4WA6A 4HXDB 5EGWA 1PE6A 4BOPA 1VJVA 1KXRA 4BOSA 2PREA 4YV8A 4X6IA 2FUDA 4FK5A 4D8IA 3WXGA 6PADA 3OF8A 2FRQA 4D8EA 4BOUA 2NQIA 1PBHA 2DJFB 3N4CA 2JTCA 2Y5BA 1HUCB 4OEMA 2HXZA 1QDQA 5CHVA 3HHIA 2H7JA 1PVJA 3IUTA 1YK7A 1CJLA 4I05A 5A24A 2O6XA 2E02A 3E9SA 4QRXA 1VSNA 1MEMA 4GUAA 4MZOA 4W4UA 3C9EA 4RF0A 1BP4A 2BU3A 3DF0A 1DEUA 3QJ3A 1PADA 2IBIA 3BBAA 3H89A 3PW3A 1TU6A 3WXFA 1AIMA 2AU1A 4P6GA 4N8WA 1CB5A 4FIPA 2DCDA 3MTNA 4YYWA 4YYUA 4ZUXU 4IP3A 3BCNA 3CBKA 1CQDA 1XKGA 1O0EA 1PIPA 3M99A 1U9WA 3KX1A 2AIMA 1IWDA 3TMPA 3K8UA 8PCHA 3OF9A 3K24A 1POPA 1S4VA 3F75A 2HH5A 4YYQA 3KSEA 4BQVA 5J94A 3PHWA 1GLOA 3I06A 5KO3A 2R9FA 2CB5A 3PT2A 3S3RA 1BGOA 1TLOA 1EWOA 5F02A 1ME3A 1Q6KA 4P6EA 3MTVA 3TRKA 2J7QA 2F1GA 1Y4HA 1UKFA 2VHFA 1AYUA 1YK8A 3N3GA 4R3DA 2PNSA 2YJ8A 1DKIA 2XU5A 1MHWA 4I07A 3NHEA 1AYVA 1EWMA 3MP2A 1PPOA 1U9VA 1NB3A 2IPPB 4MSXA 3GCBA 5CHTA 1CSBB 1F2BA 3HD3A 3IEJA 3P5UA 3V6EA 4OW0A 1YALA 2AYNA 2NQDB 3IMAA 4MI7A 3PNRA 3H8BA 1MIRA 2DJGB 1AYWA 1X9YA 4AXLA 2J7QC 3QSDA 3W30A 2ACTA 3P5XA 1PXVA 2YJ9A 2G7YA 1Y08A 2JRIA 3K9MA 4G54A 4OVZB 2HD5A 1TL9A 4PADA 3U8EA 4MM3B 3BPFA 1KFUL 2B1MA 3IHPA 3RVWA
chains in the Genus database with same CATH topology
2DC7A 3IOQA 4BS6A 2AYOA 2E03A 3D6SA 1ICFA 3I3TA 2P86A 3H6SA 4KLBA 4XUIA 2PADA 2G8JA 1AU4A 2B1NA 4QBBA 1DF0A 1W4TA 4QH6A 3O0UA 4PI3A 4X6JA 3AI8A 1CVZA 2BDZA 2OZ2A 1NQCA 4I04A 2DZYA 4YYVA 1QMYA 3PDFA 2DCBA 3BPMA 2XU1A 2F7DA 1GMYA 2OULA 3CH2X 3BWKA 2HHNA 1GCBA 1F29A 4DMYA 1K3BB 3CH3X 3OVXA 1F2CA 4AXMA 4CDDB 1CPJA 1GECE 3QT4A 3KWBX 3CBJA 3H8CA 2YJCA 4CDEB 2DC6A 3ERVA 2R9MA 1STFE 2ATOA 1EWPA 4MZSA 2Y6EA 4RY2A 3USVA 4YVAA 2OP3A 2R9OA 9PAPA 4Q8HA 1SNKA 3V6CA 3RVXA 4W5BA 1F2AA 5JH3A 2BSZA 1GX3A 5K16A 3H7DA 4K7CA 1ATKA 3E1ZB 2NQGA 1ZCMA 2P0RA 1NB5A 1ITOA 5CVOB 1M6DA 1AU2A 1AECA 2VFBA 1A6RA 1QXPA 1AU0A 2E00A 2DZZA 2PBHA 5EF4A 4C5PA 5CVMA 3OISA 4N4ZA 1KFXL 4PP2E 4N79A 1SP4B 3HWNA 2DC9A 1CTEA 2DCAA 1KHPA 1NPZA 1EWLA 4YYSA 3O1GA 1BY8A 1PCIA 2FT2A 1AU3A 3IV2A 3KKUA 3MORA 1PPDA 2FRAA 1ME4A 2G6DA 4B55A 5CVNB 2YJBA 1U9XA 2XU4A 2GFOA 1NLJA 4GUZA 3N3KA 2E01A 2WBFX 1QOLA 1CS8A 4XR7A 1MS6A 3HHAA 4BPVA 1BQIA 4YYRA 1YVBA 3P5WA 5PADA 1MEGA 2AVWA 4QRVA 2FTDA 3WXEA 2FO5A 1EF7A 3MHSA 2P7UA 4DMXA 1FH0A 3KWZA 3KFQA 5JA7A 4W5CA 1U5IA 2YJ2A 3KW9A 2AS8A 4PP1A 1KHQA 2JQFR 1PPPA 1CV8A 3LFYA 3F5VA 4BSQA 1THEA 2GHUA 1MDWA 3ZUAA 2C0YA 3BC3A 1JQPA 2AUZA 3B79A 2FYEA 4X6HA 5FPWA 2DCCA 3S3QA 4FJCA 4QRGA 3PBHA 4HWYA 4CZWA 1NL6A 3OVZA 2FQ9A 3P5VA 4CDCB 2G8EA 1ZIVA 1PPNA 3RVVA 2VHSA 2ARYA 3LXSA 7PCKA 2AUXA 1YT7A 3MHHA 2R9CA 2XU3A 2DC8A 1U9QX 2NQAA 4Q8GA 4BS5A 4OELA 4CDFB 2JQGR 2R6NA 2R9NA 3BOWA 2BDLA 2CIOA 3TNXA 4WA6A 5EGWA 1E2TA 1PE6A 1VJVA 1KXRA 2PREA 4YV8A 4X6IA 2FUDA 4FK5A 3WXGA 6PADA 3OF8A 2FRQA 3D9WA 2NQIA 1PBHA 2DJFB 3N4CA 2Y5BA 1HUCB 4OEMA 2HXZA 1QDQA 5CHVA 4BGFA 3HHIA 2H7JA 3IUTA 1YK7A 1CJLA 4I05A 5A24A 2O6XA 2E02A 4QRXA 1VSNA 1MEMA 4MZOA 4W4UA 3C9EA 1BP4A 3DF0A 1DEUA 3QJ3A 1PADA 2IBIA 3H89A 3PW3A 1TU6A 3WXFA 1AIMA 2AU1A 4P6GA 4N8WA 1W5RA 1CB5A 4FIPA 2DCDA 3MTNA 2VFCA 4YYWA 4YYUA 4ZUXU 1W6FA 3BCNA 3CBKA 1CQDA 1XKGA 1O0EA 1PIPA 3M99A 1U9WA 3KX1A 2AIMA 1IWDA 3K8UA 8PCHA 3LTWA 3OF9A 3K24A 1POPA 1S4VA 3F75A 2HH5A 4YYQA 3KSEA 4BQVA 5J94A 4NV7A 1GLOA 3I06A 2R9FA 2CB5A 3S3RA 1BGOA 1TLOA 1EWOA 5F02A 1ME3A 1Q6KA 4P6EA 2F1GA 1Y4HA 2VHFA 1AYUA 1YK8A 3N3GA 2PNSA 2YJ8A 2XU5A 1MHWA 4I07A 3NHEA 1AYVA 1EWMA 1PPOA 1U9VA 1NB3A 2IPPB 4MSXA 3GCBA 5CHTA 1CSBB 1F2BA 3HD3A 3IEJA 3P5UA 3V6EA 1YALA 2AYNA 2NQDB 3IMAA 3PNRA 3H8BA 1MIRA 2DJGB 1AYWA 1X9YA 4AXLA 3QSDA 2ACTA 3P5XA 1PXVA 2YJ9A 2G7YA 1Y08A 3K9MA 4G54A 2HD5A 1TL9A 4PADA 3U8EA 3BPFA 1KFUL 4NV8A 2B1MA 3IHPA 3RVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DC7 A;  3IOQ A;  4BS6 A;  2AYO A;  2E03 A;  3D6S A;  1ICF A;  3I3T A;  2P86 A;  3H6S A;  4KLB A;  4XUI A;  2PAD A;  2G8J A;  1AU4 A;  2B1N A;  4QBB A;  1DF0 A;  4QH6 A;  3O0U A;  4PI3 A;  4X6J A;  3AI8 A;  1CVZ A;  2BDZ A;  2OZ2 A;  1NQC A;  4I04 A;  2DZY A;  4YYV A;  1QMY A;  3PDF A;  3IHP A;  2DCB A;  3BPM A;  2XU1 A;  2F7D A;  1GMY A;  2OUL A;  3CH2 X;  3BWK A;  2HHN A;  1GCB A;  1F29 A;  4DMY A;  1K3B B;  3CH3 X;  3OVX A;  1F2C A;  4AXM A;  4CDD B;  1CPJ A;  1GEC E;  3QT4 A;  3KWB X;  3CBJ A;  3H8C A;  2YJC A;  4CDE B;  2DC6 A;  3ERV A;  2R9M A;  1STF E;  2ATO A;  1EWP A;  4MZS A;  2Y6E A;  4RY2 A;  3USV A;  4YVA A;  2OP3 A;  2R9O A;  9PAP A;  4Q8H A;  1SNK A;  3V6C A;  3RVX A;  4W5B A;  1F2A A;  5JH3 A;  5K16 A;  3H7D A;  4K7C A;  1ATK A;  3E1Z B;  2NQG A;  1ZCM A;  2P0R A;  1NB5 A;  1ITO A;  5CVO B;  1M6D A;  1AU2 A;  1AEC A;  1A6R A;  1QXP A;  1AU0 A;  2E00 A;  2DZZ A;  2PBH A;  5EF4 A;  5CVM A;  3OIS A;  4N4Z A;  1KFX L;  4PP2 E;  4N79 A;  1SP4 B;  3HWN A;  2DC9 A;  1CTE A;  2DCA A;  1KHP A;  1NPZ A;  1EWL A;  4YYS A;  3O1G A;  1BY8 A;  1PCI A;  2FT2 A;  1AU3 A;  3IV2 A;  3KKU A;  3MOR A;  1PPD A;  2FRA A;  1ME4 A;  2G6D A;  5CVN B;  2YJB A;  1U9X A;  2XU4 A;  2GFO A;  1NLJ A;  3N3K A;  2E01 A;  2WBF X;  1QOL A;  1CS8 A;  4XR7 A;  1MS6 A;  3HHA A;  4BPV A;  1BQI A;  4YYR A;  1YVB A;  3P5W A;  5PAD A;  1MEG A;  2AVW A;  4QRV A;  2FTD A;  3WXE A;  2FO5 A;  1EF7 A;  3MHS A;  2P7U A;  4DMX A;  1FH0 A;  3KWZ A;  3KFQ A;  5JA7 A;  4W5C A;  1U5I A;  2YJ2 A;  3KW9 A;  2AS8 A;  4PP1 A;  1KHQ A;  2JQF R;  1PPP A;  1CV8 A;  3LFY A;  3F5V A;  4BSQ A;  1THE A;  2GHU A;  1MDW A;  3ZUA A;  2C0Y A;  3BC3 A;  1JQP A;  2AUZ A;  3B79 A;  2FYE A;  4X6H A;  5FPW A;  2DCC A;  3S3Q A;  4FJC A;  4QRG A;  3PBH A;  4HWY A;  4CZW A;  1NL6 A;  3OVZ A;  2FQ9 A;  3P5V A;  4CDC B;  2G8E A;  1ZIV A;  1PPN A;  3RVV A;  2VHS A;  2ARY A;  3LXS A;  7PCK A;  2AUX A;  1YT7 A;  3MHH A;  2R9C A;  2XU3 A;  2DC8 A;  1U9Q X;  2NQA A;  4Q8G A;  4BS5 A;  4OEL A;  4CDF B;  2JQG R;  2R6N A;  2R9N A;  3BOW A;  2BDL A;  2CIO A;  3TNX A;  4WA6 A;  5EGW A;  1PE6 A;  1VJV A;  1KXR A;  2PRE A;  4YV8 A;  4X6I A;  2FUD A;  4FK5 A;  3WXG A;  6PAD A;  3OF8 A;  2FRQ A;  2NQI A;  1PBH A;  2DJF B;  3N4C A;  2Y5B A;  1HUC B;  2HXZ A;  1QDQ A;  5CHV A;  3HHI A;  2H7J A;  3IUT A;  1YK7 A;  1CJL A;  4I05 A;  5A24 A;  2O6X A;  2E02 A;  4QRX A;  1VSN A;  1MEM A;  4MZO A;  4W4U A;  3C9E A;  1BP4 A;  3DF0 A;  1DEU A;  3QJ3 A;  1PAD A;  2IBI A;  3H89 A;  3PW3 A;  1TU6 A;  3WXF A;  1AIM A;  2AU1 A;  4P6G A;  4N8W A;  1CB5 A;  4FIP A;  2DCD A;  3MTN A;  4YYW A;  4YYU A;  4ZUX U;  3BCN A;  3CBK A;  1CQD A;  1XKG A;  1O0E A;  1PIP A;  3M99 A;  1U9W A;  3KX1 A;  2AIM A;  1IWD A;  3K8U A;  8PCH A;  3OF9 A;  3K24 A;  1POP A;  1S4V A;  3F75 A;  2HH5 A;  4YYQ A;  3KSE A;  4BQV A;  5J94 A;  1GLO A;  3I06 A;  2R9F A;  2CB5 A;  3S3R A;  1BGO A;  1TLO A;  1EWO A;  5F02 A;  1ME3 A;  1Q6K A;  4P6E A;  2F1G A;  1Y4H A;  2VHF A;  1AYU A;  1YK8 A;  3N3G A;  2PNS A;  2YJ8 A;  2XU5 A;  1MHW A;  4I07 A;  3NHE A;  1AYV A;  1EWM A;  1PPO A;  1U9V A;  1NB3 A;  2IPP B;  4MSX A;  3GCB A;  5CHT A;  1CSB B;  1F2B A;  3HD3 A;  3IEJ A;  3P5U A;  3V6E A;  1YAL A;  2AYN A;  2NQD B;  3IMA A;  3PNR A;  3H8B A;  1MIR A;  2DJG B;  1AYW A;  1X9Y A;  4AXL A;  3QSD A;  2ACT A;  3P5X A;  1PXV A;  2YJ9 A;  2G7Y A;  1Y08 A;  3K9M A;  4G54 A;  2HD5 A;  1TL9 A;  4PAD A;  3U8E A;  3BPF A;  1KFU L;  2B1M A;  4OEM A;  3RVW A; 
#chains in the Genus database with same CATH topology
 2DC7 A;  3IOQ A;  4BS6 A;  2AYO A;  2E03 A;  3D6S A;  3BY4 A;  1ICF A;  3I3T A;  4ZTB A;  2BTW B;  2P86 A;  3H6S A;  3C0R A;  4KLB A;  4XUI A;  2PAD A;  2G8J A;  1AU4 A;  2B1N A;  4QBB A;  1DF0 A;  3IFU A;  4QH6 A;  2FE8 A;  3O0U A;  3BB7 A;  4PI3 A;  3B21 A;  4X6J A;  3AI8 A;  1CVZ A;  2BDZ A;  2OZ2 A;  1NQC A;  4I04 A;  2DZY A;  4P16 A;  4YYV A;  5E6J A;  1QMY A;  3PDF A;  2DCB A;  3BPM A;  2XU1 A;  2F7D A;  1GMY A;  2OUL A;  3CH2 X;  3BWK A;  2HHN A;  1GCB A;  1F29 A;  4DMY A;  1K3B B;  3CH3 X;  3OVX A;  1F2C A;  4AXM A;  4CDD B;  1CPJ A;  1GEC E;  3ZNH A;  3QT4 A;  3KWB X;  3CBJ A;  3H8C A;  2YJC A;  4CDE B;  2DC6 A;  3ERV A;  2R9M A;  1STF E;  2ATO A;  1EWP A;  4MZS A;  5EZQ A;  2Y6E A;  4RY2 A;  3USV A;  4YVA A;  2OP3 A;  2R9O A;  9PAP A;  4D8B A;  4Q8H A;  1SNK A;  4IUM A;  3V6C A;  4RKX A;  3RVX A;  4W5B A;  2HWK A;  1F2A A;  5JH3 A;  5K16 A;  3PRM A;  3H7D A;  4K7C A;  1ATK A;  4OVZ A;  3E1Z B;  2NQG A;  1ZCM A;  2P0R A;  4RF1 A;  1NB5 A;  1ITO A;  5CVO B;  2Z84 A;  1M6D A;  1AU2 A;  1AEC A;  3PRP A;  1A6R A;  1QXP A;  1AU0 A;  2E00 A;  2DZZ A;  2PBH A;  5EF4 A;  2AGA A;  5CVM A;  3OIS A;  4N4Z A;  1KFX L;  2BTW A;  4PP2 E;  4N79 A;  1SP4 B;  3HWN A;  2DC9 A;  1CTE A;  2DCA A;  1KHP A;  1NPZ A;  1EWL A;  4YYS A;  3O1G A;  3PHX A;  1BY8 A;  3W31 A;  1PCI A;  2FT2 A;  1AU3 A;  3IV2 A;  3KKU A;  3MOR A;  1PPD A;  2FRA A;  1ME4 A;  2G6D A;  5CVN B;  1YZB A;  2YJB A;  1U9X A;  2XU4 A;  2GFO A;  1NLJ A;  3O65 A;  2DOS A;  4BOQ A;  3N3K A;  2E01 A;  2WBF X;  1QOL A;  1CS8 A;  4XR7 A;  1MS6 A;  3HHA A;  4WUR A;  4BPV A;  1BQI A;  4YYR A;  1YVB A;  3P5W A;  5EZS A;  5PAD A;  1MEG A;  2AVW A;  4QRV A;  2FTD A;  3WXE A;  2FO5 A;  1EF7 A;  3MHS A;  2P7U A;  4XZX A;  4DMX A;  1FH0 A;  3KWZ A;  3KFQ A;  5JA7 A;  4W5C A;  1U5I A;  2YJ2 A;  3KW9 A;  3MJ5 A;  2AS8 A;  4PP1 A;  1KHQ A;  2JQF R;  5JZE A;  1PPP A;  1CV8 A;  3LFY A;  3F5V A;  4BSQ A;  1THE A;  2GHU A;  4BOZ A;  1MDW A;  3ZUA A;  2C0Y A;  3BC3 A;  1JQP A;  2AUZ A;  3B79 A;  2FYE A;  4X6H A;  5FPW A;  4RNA A;  2DCC A;  4A5U A;  4M0W A;  3S3Q A;  2UZJ A;  4FJC A;  4QRG A;  4REZ A;  3PBH A;  4HWY A;  4CZW A;  1NL6 A;  3OVZ A;  2FQ9 A;  3P5V A;  4CDC B;  2G8E A;  1ZIV A;  1PPN A;  3RVV A;  4PT5 A;  2VHS A;  2ARY A;  3LXS A;  3PSE A;  7PCK A;  2AUX A;  1YT7 A;  3MHH A;  2R9C A;  2XU3 A;  2DC8 A;  1U9Q X;  2NQA A;  4Q8G A;  4BS5 A;  3OQC A;  4OEL A;  4CDF B;  3PHU A;  2JQG R;  2R6N A;  2R9N A;  3BOW A;  3RNV A;  2BDL A;  2CIO A;  3TNX A;  4WA6 A;  4HXD B;  5EGW A;  1PE6 A;  4BOP A;  1VJV A;  1KXR A;  4BOS A;  2PRE A;  4YV8 A;  4X6I A;  2FUD A;  4FK5 A;  4D8I A;  3WXG A;  6PAD A;  3OF8 A;  2FRQ A;  4D8E A;  4BOU A;  2NQI A;  1PBH A;  2DJF B;  3N4C A;  2JTC A;  2Y5B A;  1HUC B;  4OEM A;  2HXZ A;  1QDQ A;  5CHV A;  3HHI A;  2H7J A;  1PVJ A;  3IUT A;  1YK7 A;  1CJL A;  4I05 A;  5A24 A;  2O6X A;  2E02 A;  3E9S A;  4QRX A;  1VSN A;  1MEM A;  4GUA A;  4MZO A;  4W4U A;  3C9E A;  4RF0 A;  1BP4 A;  2BU3 A;  3DF0 A;  1DEU A;  3QJ3 A;  1PAD A;  2IBI A;  3BBA A;  3H89 A;  3PW3 A;  1TU6 A;  3WXF A;  1AIM A;  2AU1 A;  4P6G A;  4N8W A;  1CB5 A;  4FIP A;  2DCD A;  3MTN A;  4YYW A;  4YYU A;  4ZUX U;  4IP3 A;  3BCN A;  3CBK A;  1CQD A;  1XKG A;  1O0E A;  1PIP A;  3M99 A;  1U9W A;  3KX1 A;  2AIM A;  1IWD A;  3TMP A;  3K8U A;  8PCH A;  3OF9 A;  3K24 A;  1POP A;  1S4V A;  3F75 A;  2HH5 A;  4YYQ A;  3KSE A;  4BQV A;  5J94 A;  3PHW A;  1GLO A;  3I06 A;  5KO3 A;  2R9F A;  2CB5 A;  3PT2 A;  3S3R A;  1BGO A;  1TLO A;  1EWO A;  5F02 A;  1ME3 A;  1Q6K A;  4P6E A;  3MTV A;  3TRK A;  2J7Q A;  2F1G A;  1Y4H A;  1UKF A;  2VHF A;  1AYU A;  1YK8 A;  3N3G A;  4R3D A;  2PNS A;  2YJ8 A;  1DKI A;  2XU5 A;  1MHW A;  4I07 A;  3NHE A;  1AYV A;  1EWM A;  3MP2 A;  1PPO A;  1U9V A;  1NB3 A;  2IPP B;  4MSX A;  3GCB A;  5CHT A;  1CSB B;  1F2B A;  3HD3 A;  3IEJ A;  3P5U A;  3V6E A;  4OW0 A;  1YAL A;  2AYN A;  2NQD B;  3IMA A;  4MI7 A;  3PNR A;  3H8B A;  1MIR A;  2DJG B;  1AYW A;  1X9Y A;  4AXL A;  2J7Q C;  3QSD A;  3W30 A;  2ACT A;  3P5X A;  1PXV A;  2YJ9 A;  2G7Y A;  1Y08 A;  2JRI A;  3K9M A;  4G54 A;  4OVZ B;  2HD5 A;  1TL9 A;  4PAD A;  3U8E A;  4MM3 B;  3BPF A;  1KFU L;  2B1M A;  3IHP A;  3RVW A; 
#chains in the Genus database with same CATH homology
 2DC7 A;  3IOQ A;  4BS6 A;  2AYO A;  2E03 A;  3D6S A;  1ICF A;  3I3T A;  2P86 A;  3H6S A;  4KLB A;  4XUI A;  2PAD A;  2G8J A;  1AU4 A;  2B1N A;  4QBB A;  1DF0 A;  1W4T A;  4QH6 A;  3O0U A;  4PI3 A;  4X6J A;  3AI8 A;  1CVZ A;  2BDZ A;  2OZ2 A;  1NQC A;  4I04 A;  2DZY A;  4YYV A;  1QMY A;  3PDF A;  2DCB A;  3BPM A;  2XU1 A;  2F7D A;  1GMY A;  2OUL A;  3CH2 X;  3BWK A;  2HHN A;  1GCB A;  1F29 A;  4DMY A;  1K3B B;  3CH3 X;  3OVX A;  1F2C A;  4AXM A;  4CDD B;  1CPJ A;  1GEC E;  3QT4 A;  3KWB X;  3CBJ A;  3H8C A;  2YJC A;  4CDE B;  2DC6 A;  3ERV A;  2R9M A;  1STF E;  2ATO A;  1EWP A;  4MZS A;  2Y6E A;  4RY2 A;  3USV A;  4YVA A;  2OP3 A;  2R9O A;  9PAP A;  4Q8H A;  1SNK A;  3V6C A;  3RVX A;  4W5B A;  1F2A A;  5JH3 A;  2BSZ A;  1GX3 A;  5K16 A;  3H7D A;  4K7C A;  1ATK A;  3E1Z B;  2NQG A;  1ZCM A;  2P0R A;  1NB5 A;  1ITO A;  5CVO B;  1M6D A;  1AU2 A;  1AEC A;  2VFB A;  1A6R A;  1QXP A;  1AU0 A;  2E00 A;  2DZZ A;  2PBH A;  5EF4 A;  4C5P A;  5CVM A;  3OIS A;  4N4Z A;  1KFX L;  4PP2 E;  4N79 A;  1SP4 B;  3HWN A;  2DC9 A;  1CTE A;  2DCA A;  1KHP A;  1NPZ A;  1EWL A;  4YYS A;  3O1G A;  1BY8 A;  1PCI A;  2FT2 A;  1AU3 A;  3IV2 A;  3KKU A;  3MOR A;  1PPD A;  2FRA A;  1ME4 A;  2G6D A;  4B55 A;  5CVN B;  2YJB A;  1U9X A;  2XU4 A;  2GFO A;  1NLJ A;  4GUZ A;  3N3K A;  2E01 A;  2WBF X;  1QOL A;  1CS8 A;  4XR7 A;  1MS6 A;  3HHA A;  4BPV A;  1BQI A;  4YYR A;  1YVB A;  3P5W A;  5PAD A;  1MEG A;  2AVW A;  4QRV A;  2FTD A;  3WXE A;  2FO5 A;  1EF7 A;  3MHS A;  2P7U A;  4DMX A;  1FH0 A;  3KWZ A;  3KFQ A;  5JA7 A;  4W5C A;  1U5I A;  2YJ2 A;  3KW9 A;  2AS8 A;  4PP1 A;  1KHQ A;  2JQF R;  1PPP A;  1CV8 A;  3LFY A;  3F5V A;  4BSQ A;  1THE A;  2GHU A;  1MDW A;  3ZUA A;  2C0Y A;  3BC3 A;  1JQP A;  2AUZ A;  3B79 A;  2FYE A;  4X6H A;  5FPW A;  2DCC A;  3S3Q A;  4FJC A;  4QRG A;  3PBH A;  4HWY A;  4CZW A;  1NL6 A;  3OVZ A;  2FQ9 A;  3P5V A;  4CDC B;  2G8E A;  1ZIV A;  1PPN A;  3RVV A;  2VHS A;  2ARY A;  3LXS A;  7PCK A;  2AUX A;  1YT7 A;  3MHH A;  2R9C A;  2XU3 A;  2DC8 A;  1U9Q X;  2NQA A;  4Q8G A;  4BS5 A;  4OEL A;  4CDF B;  2JQG R;  2R6N A;  2R9N A;  3BOW A;  2BDL A;  2CIO A;  3TNX A;  4WA6 A;  5EGW A;  1E2T A;  1PE6 A;  1VJV A;  1KXR A;  2PRE A;  4YV8 A;  4X6I A;  2FUD A;  4FK5 A;  3WXG A;  6PAD A;  3OF8 A;  2FRQ A;  3D9W A;  2NQI A;  1PBH A;  2DJF B;  3N4C A;  2Y5B A;  1HUC B;  4OEM A;  2HXZ A;  1QDQ A;  5CHV A;  4BGF A;  3HHI A;  2H7J A;  3IUT A;  1YK7 A;  1CJL A;  4I05 A;  5A24 A;  2O6X A;  2E02 A;  4QRX A;  1VSN A;  1MEM A;  4MZO A;  4W4U A;  3C9E A;  1BP4 A;  3DF0 A;  1DEU A;  3QJ3 A;  1PAD A;  2IBI A;  3H89 A;  3PW3 A;  1TU6 A;  3WXF A;  1AIM A;  2AU1 A;  4P6G A;  4N8W A;  1W5R A;  1CB5 A;  4FIP A;  2DCD A;  3MTN A;  2VFC A;  4YYW A;  4YYU A;  4ZUX U;  1W6F A;  3BCN A;  3CBK A;  1CQD A;  1XKG A;  1O0E A;  1PIP A;  3M99 A;  1U9W A;  3KX1 A;  2AIM A;  1IWD A;  3K8U A;  8PCH A;  3LTW A;  3OF9 A;  3K24 A;  1POP A;  1S4V A;  3F75 A;  2HH5 A;  4YYQ A;  3KSE A;  4BQV A;  5J94 A;  4NV7 A;  1GLO A;  3I06 A;  2R9F A;  2CB5 A;  3S3R A;  1BGO A;  1TLO A;  1EWO A;  5F02 A;  1ME3 A;  1Q6K A;  4P6E A;  2F1G A;  1Y4H A;  2VHF A;  1AYU A;  1YK8 A;  3N3G A;  2PNS A;  2YJ8 A;  2XU5 A;  1MHW A;  4I07 A;  3NHE A;  1AYV A;  1EWM A;  1PPO A;  1U9V A;  1NB3 A;  2IPP B;  4MSX A;  3GCB A;  5CHT A;  1CSB B;  1F2B A;  3HD3 A;  3IEJ A;  3P5U A;  3V6E A;  1YAL A;  2AYN A;  2NQD B;  3IMA A;  3PNR A;  3H8B A;  1MIR A;  2DJG B;  1AYW A;  1X9Y A;  4AXL A;  3QSD A;  2ACT A;  3P5X A;  1PXV A;  2YJ9 A;  2G7Y A;  1Y08 A;  3K9M A;  4G54 A;  2HD5 A;  1TL9 A;  4PAD A;  3U8E A;  3BPF A;  1KFU L;  4NV8 A;  2B1M A;  3IHP A;  3RVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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