2C0YA

The crystal structure of a cys25ala mutant of human procathepsin s
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
314
structure length
308
Chain Sequence
LHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYILPDSVDWREKGCVTEVKYQGSCGAAWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structure of a Cys25 -> Ala Mutant of Human Procathepsin S Elucidates Enzyme-Prosequence Interactions.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PROCATHEPSIN S
total genus 104
structure length 308
sequence length 314
ec nomenclature ec 3.4.22.27: Cathepsin S.
pdb deposition date 2005-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2c0yA00
2F1GA 4PP2E 2AUXA 2OZ2A 4AXMA 1ITOA 1MIRA 1ATKA 1NL6A 1YK8A 4N4ZA 6PADA 3P5UA 3V6EA 2OULA 1HUCB 1U9WA 1SP4B 1Y08A 4Q8HA 1CQDA 1U5IA 2E03A 2B1NA 5JH3A 1PADA 1PIPA 3MTNA 3KW9A 3NHEA 2O6XA 2HH5A 2F7DA 3AI8A 2YJ9A 3D6SA 3OVXA 1YALA 4K7CA 1AU2A 3HHAA 4AXLA 1AYUA 1YK7A 3K24A 4X6IA 9PAPA 3KWZA 4ZUXU 3CH2X 2P86A 1KHQA 2FT2A 5EGWA 1FH0A 1YVBA 1NLJA 4X6JA 2GHUA 1EWOA 2Y5BA 1EWPA 3V6CA 2AU1A 2G8EA 2AYOA 2DJGB 4Q8GA 3KX1A 1TLOA 3QT4A 2NQDB 1NQCA 3H8BA 3BWKA 3LFYA 2G7YA 2HD5A 3P5XA 2WBFX 1QOLA 2DZZA 2XU3A 1ME3A 3N4CA 1GMYA 1CS8A 1ME4A 2BDZA 1ZIVA 1PPOA 1MHWA 3I3TA 4W4UA 1NB5A 3USVA 1JQPA 4MZSA 4YYVA 1TL9A 4XR7A 5CVOB 3CBJA 1S4VA 2DJFB 3TNXA 2HHNA 3M99A 4YVAA 4PI3A 1U9VA 1POPA 2FRQA 2DZYA 2B1MA 2HXZA 3O1GA 4YYQA 3CH3X 3QJ3A 1SNKA 2FUDA 1CVZA 4YV8A 1XKGA 2R9NA 3P5VA 4DMXA 1PE6A 1U9XA 1QDQA 2C0YA 5J94A 3PBHA 1CV8A 1QXPA 3IUTA 1MEMA 5JA7A 4I05A 2VHFA 2BDLA 3RVWA 2YJCA 3K9MA 2ARYA 3H8CA 4P6GA 3PW3A 4BPVA 3HD3A 4I07A 2H7JA 3P5WA 1BQIA 1F2CA 3LXSA 3O0UA 3MHSA 1DF0A 4G54A 2P0RA 2NQGA 1AU3A 2E01A 3IMAA 1ZCMA 3PNRA 4BS5A 4OEMA 1EWLA 4PADA 4CDDB 3KWBX 4YYUA 4PP1A 2FO5A 5PADA 3H6SA 4MSXA 3N3GA 5K16A 1A6RA 2NQIA 3IEJA 2JQGR 2XU1A 3PDFA 2DCAA 4CDCB 2P7UA 4HWYA 2FQ9A 2GFOA 5FPWA 3BOWA 4QRVA 3BPFA 1PXVA 1AU0A 2CIOA 1AYVA 2IPPB 5A24A 2DC8A 3IV2A 2E00A 4WA6A 3RVXA 1GECE 2IBIA 1TU6A 2YJBA 5CVMA 2R9CA 2FYEA 2R9FA 1ICFA 3KSEA 2DC6A 3BPMA 4P6EA 4QH6A 3BC3A 1GLOA 1BP4A 2XU5A 2DC9A 2XU4A 4N8WA 3CBKA 1GCBA 2DCDA 4FIPA 3OF9A 4XUIA 4W5CA 1PCIA 4FK5A 3F5VA 1KXRA 3HWNA 1BGOA 2PNSA 1MEGA 1VSNA 3I06A 1MS6A 1THEA 2VHSA 1KHPA 2AUZA 2R9MA 2AYNA 3RVVA 1X9YA 2YJ2A 4YYWA 3OF8A 2PREA 1CPJA 2AVWA 1IWDA 2Y6EA 1CTEA 1STFE 3MHHA 4QBBA 4MZOA 4I04A 4CDFB 2FTDA 1F2AA 3H89A 1AYWA 2YJ8A 3K8UA 1F2BA 3KFQA 4YYRA 1PPDA 3WXEA 3U8EA 2FRAA 1O0EA 5CHTA 4YYSA 3WXFA 3C9EA 3OISA 1NB3A 1U9QX 5EF4A 3S3RA 2CB5A 3GCBA 4BSQA 3BCNA 4FJCA 1DEUA 1MDWA 4KLBA 4CZWA 3OVZA 1KFUL 1EF7A 3DF0A 3MORA 3F75A 4OELA 3ZUAA 1QMYA 2ATOA 3IOQA 1AU4A 1Q6KA 2PBHA 1VJVA 2G6DA 2AIMA 3ERVA 1CB5A 5F02A 1K3BB 4X6HA 3S3QA 4BQVA 1PPNA 1NPZA 2R9OA 1Y4HA 1CJLA 1KFXL 3HHIA 1PPPA 8PCHA 1YT7A 1CSBB 2G8JA 2JQFR 2PADA 4QRGA 1AIMA 2DC7A 2NQAA 4QRXA 1F29A 4N79A 4CDEB 4DMYA 1PBHA 3N3KA 1AECA 2E02A 2DCBA 5CHVA 3B79A 2ACTA 3WXGA 4W5BA 1BY8A 4RY2A 2R6NA 3QSDA 7PCKA 3H7DA 1M6DA 3IHPA 2AS8A 5CVNB 2OP3A 3E1ZB 1EWMA 2DCCA 3KKUA 4BS6A
chains in the Genus database with same CATH superfamily
2F1GA 4PP2E 2AUXA 4OVZA 2OZ2A 4AXMA 1ITOA 1MIRA 1ATKA 1NL6A 1YK8A 4N4ZA 6PADA 3P5UA 3V6EA 2OULA 1HUCB 4D8EA 1UKFA 1U9WA 1SP4B 3BY4A 1Y08A 4Q8HA 1CQDA 1U5IA 2E03A 2B1NA 5JH3A 1PVJA 1PADA 1PIPA 3MTNA 4A5UA 3KW9A 2HWKA 3NHEA 2O6XA 2HH5A 2F7DA 3AI8A 5E6JA 2YJ9A 3D6SA 3OVXA 1YALA 4REZA 4K7CA 1AU2A 4MM3B 3HHAA 4AXLA 1AYUA 1YK7A 3K24A 4X6IA 9PAPA 4BOQA 3KWZA 4ZUXU 3CH2X 2P86A 1KHQA 2FT2A 5EGWA 1FH0A 3MJ5A 4BOSA 1YVBA 3B21A 2JTCA 1NLJA 4RF0A 4X6JA 2GHUA 3MP2A 1EWOA 2Y5BA 1EWPA 3V6CA 2AU1A 2G8EA 2AYOA 2DJGB 4Q8GA 3KX1A 1TLOA 3QT4A 2NQDB 1NQCA 3H8BA 3BWKA 4GUAA 3LFYA 2G7YA 2HD5A 3P5XA 2WBFX 4P16A 1QOLA 4RNAA 2DZZA 2XU3A 1ME3A 3N4CA 1GMYA 1CS8A 4RKXA 1ME4A 2BDZA 2J7QA 4D8BA 1ZIVA 1PPOA 1MHWA 3I3TA 4W4UA 1NB5A 3USVA 1JQPA 4MZSA 4YYVA 1TL9A 4XR7A 5CVOB 3CBJA 1S4VA 2DJFB 3TNXA 2HHNA 3M99A 3E9SA 4YVAA 4PI3A 1U9VA 2BTWB 1POPA 2FRQA 2DZYA 2B1MA 2HXZA 3O1GA 4YYQA 3CH3X 3QJ3A 1SNKA 2FUDA 1CVZA 4YV8A 3IFUA 1XKGA 2R9NA 3P5VA 4DMXA 1PE6A 1U9XA 1QDQA 3PSEA 2C0YA 5J94A 3PBHA 1CV8A 1QXPA 3IUTA 1MEMA 5JA7A 4I05A 4IUMA 2VHFA 2BDLA 3RVWA 2YJCA 1DKIA 3K9MA 2ARYA 3H8CA 4P6GA 3PW3A 4BPVA 3HD3A 4I07A 2H7JA 3P5WA 1BQIA 1F2CA 4D8IA 4IP3A 3LXSA 3O0UA 3MHSA 1DF0A 4G54A 2P0RA 2NQGA 1AU3A 2E01A 3IMAA 1ZCMA 3PNRA 4BS5A 4OEMA 1EWLA 4PADA 4CDDB 3KWBX 4YYUA 4PP1A 2FO5A 4OVZB 5PADA 3H6SA 4MSXA 3N3GA 5K16A 1A6RA 2NQIA 3PHXA 3IEJA 2JQGR 2XU1A 3PDFA 2DCAA 2DOSA 2JRIA 2P7UA 4CDCB 4HWYA 2FQ9A 2GFOA 5FPWA 3BOWA 4QRVA 3BPFA 1PXVA 1AU0A 2CIOA 1AYVA 4MI7A 2IPPB 4M0WA 5A24A 2DC8A 3IV2A 2E00A 4WA6A 2UZJA 3RVXA 1GECE 2IBIA 4R3DA 1TU6A 2YJBA 5CVMA 2R9CA 2FYEA 2R9FA 1ICFA 3KSEA 2BU3A 2FE8A 2DC6A 4BOPA 3BPMA 4P6EA 4QH6A 3BC3A 1GLOA 1BP4A 2XU5A 2Z84A 2DC9A 1YZBA 2XU4A 4N8WA 4WURA 3CBKA 1GCBA 2DCDA 4FIPA 2J7QC 3OF9A 4RF1A 2AGAA 4XUIA 4W5CA 1PCIA 4FK5A 3F5VA 1KXRA 3HWNA 3PRPA 1BGOA 2PNSA 1MEGA 1VSNA 3I06A 1MS6A 1THEA 2VHSA 1KHPA 2AUZA 2R9MA 4PT5A 2AYNA 3RVVA 1X9YA 2YJ2A 4YYWA 3OF8A 3OQCA 2PREA 1CPJA 4HXDB 2AVWA 1IWDA 2Y6EA 3O65A 1CTEA 3PHUA 1STFE 3C0RA 3MHHA 4QBBA 3PHWA 5EZSA 4MZOA 4I04A 4CDFB 2FTDA 1F2AA 3H89A 1AYWA 2YJ8A 3K8UA 1F2BA 3KFQA 3TRKA 4YYRA 1PPDA 4XZXA 3BB7A 3WXEA 3U8EA 2FRAA 1O0EA 5CHTA 4YYSA 3WXFA 3C9EA 3ZNHA 3OISA 1NB3A 1U9QX 5EF4A 3S3RA 2CB5A 3GCBA 4BSQA 3BCNA 4FJCA 1DEUA 1MDWA 3PRMA 4KLBA 3MTVA 4CZWA 3OVZA 1KFUL 1EF7A 3DF0A 3MORA 3F75A 4OELA 3ZUAA 1QMYA 2ATOA 3PT2A 3IOQA 4OW0A 1AU4A 1Q6KA 2PBHA 1VJVA 4BOUA 2BTWA 2G6DA 2AIMA 5KO3A 3ERVA 1CB5A 5F02A 1K3BB 4X6HA 3S3QA 4BQVA 1PPNA 1NPZA 2R9OA 1Y4HA 1CJLA 1KFXL 3HHIA 1PPPA 8PCHA 1YT7A 5JZEA 1CSBB 2G8JA 2JQFR 2PADA 4QRGA 1AIMA 2DC7A 2NQAA 4QRXA 3W30A 1F29A 4N79A 3TMPA 4CDEB 5EZQA 4DMYA 3BBAA 1PBHA 3RNVA 3N3KA 1AECA 2E02A 2DCBA 5CHVA 3B79A 2ACTA 3WXGA 4W5BA 1BY8A 4RY2A 2R6NA 4ZTBA 3QSDA 7PCKA 3H7DA 1M6DA 3W31A 3IHPA 2AS8A 5CVNB 2OP3A 3E1ZB 1EWMA 2DCCA 4BOZA 3KKUA 4BS6A
chains in the Genus database with same CATH topology
2F1GA 4PP2E 2AUXA 2OZ2A 4AXMA 1ITOA 1MIRA 1ATKA 1NL6A 1YK8A 4N4ZA 6PADA 3P5UA 3V6EA 2OULA 1HUCB 4B55A 1U9WA 1SP4B 1Y08A 4Q8HA 1CQDA 1U5IA 2E03A 2B1NA 5JH3A 1PADA 1PIPA 3MTNA 3KW9A 3NHEA 2O6XA 2HH5A 2F7DA 3AI8A 2YJ9A 3D6SA 3OVXA 1YALA 2VFBA 4K7CA 1AU2A 3HHAA 4AXLA 1AYUA 1YK7A 3K24A 4X6IA 9PAPA 1GX3A 3KWZA 4ZUXU 3CH2X 2P86A 1KHQA 2FT2A 5EGWA 1FH0A 1YVBA 1NLJA 4X6JA 2GHUA 1EWOA 2Y5BA 4GUZA 1EWPA 3V6CA 2AU1A 2G8EA 2AYOA 2DJGB 4Q8GA 3KX1A 1TLOA 3QT4A 2NQDB 1NQCA 3H8BA 3BWKA 3LFYA 2G7YA 2HD5A 3P5XA 2WBFX 1QOLA 2DZZA 2XU3A 1ME3A 3N4CA 1GMYA 1CS8A 1ME4A 2BDZA 1ZIVA 1PPOA 1MHWA 3I3TA 4W4UA 1NB5A 3USVA 1JQPA 4MZSA 4YYVA 1TL9A 4XR7A 5CVOB 3CBJA 1S4VA 2DJFB 3TNXA 2HHNA 3M99A 4YVAA 4PI3A 1U9VA 1POPA 2FRQA 2DZYA 2B1MA 2HXZA 3O1GA 4YYQA 3CH3X 3QJ3A 1SNKA 2FUDA 1CVZA 4YV8A 1XKGA 2R9NA 3P5VA 4DMXA 1PE6A 1U9XA 1W5RA 1QDQA 2C0YA 5J94A 3PBHA 1CV8A 1QXPA 3IUTA 1MEMA 5JA7A 4I05A 2VHFA 2BDLA 3RVWA 2YJCA 3K9MA 2ARYA 3H8CA 4P6GA 3PW3A 4BPVA 3HD3A 4I07A 2BSZA 3D9WA 2H7JA 3P5WA 1BQIA 1F2CA 4BGFA 3LXSA 3O0UA 3MHSA 1DF0A 4G54A 2P0RA 2NQGA 1AU3A 2E01A 3IMAA 1ZCMA 3PNRA 4BS5A 4OEMA 1EWLA 4PADA 4CDDB 3KWBX 4YYUA 4PP1A 2FO5A 5PADA 3H6SA 4MSXA 3N3GA 5K16A 1A6RA 2NQIA 3IEJA 2JQGR 2XU1A 3PDFA 2DCAA 4CDCB 2P7UA 4HWYA 2FQ9A 2GFOA 5FPWA 3BOWA 4QRVA 3BPFA 1PXVA 1AU0A 2CIOA 1AYVA 2IPPB 5A24A 2DC8A 3IV2A 2E00A 4WA6A 3RVXA 1GECE 2IBIA 1TU6A 2YJBA 5CVMA 2R9CA 2FYEA 2R9FA 1ICFA 3KSEA 2DC6A 3BPMA 4P6EA 4QH6A 3BC3A 1GLOA 1BP4A 2XU5A 2DC9A 2XU4A 4N8WA 3CBKA 1GCBA 2DCDA 4FIPA 3OF9A 4XUIA 4W5CA 1PCIA 4FK5A 3F5VA 1KXRA 3HWNA 1BGOA 2PNSA 1MEGA 1VSNA 3I06A 1MS6A 1THEA 2VHSA 1KHPA 2AUZA 2R9MA 2AYNA 3RVVA 1X9YA 2YJ2A 4YYWA 3OF8A 2PREA 1CPJA 2AVWA 1IWDA 2Y6EA 1CTEA 1E2TA 1STFE 4NV8A 3MHHA 4QBBA 4MZOA 4I04A 4CDFB 2FTDA 1F2AA 3H89A 4NV7A 1AYWA 2YJ8A 3K8UA 1F2BA 3KFQA 4YYRA 1PPDA 3WXEA 3U8EA 2FRAA 1O0EA 5CHTA 4YYSA 3WXFA 3C9EA 3OISA 1NB3A 1U9QX 5EF4A 3S3RA 2CB5A 3GCBA 4BSQA 3BCNA 4FJCA 1W6FA 1DEUA 1MDWA 4KLBA 4CZWA 3OVZA 1KFUL 2VFCA 1EF7A 3DF0A 3MORA 3F75A 4OELA 3ZUAA 1QMYA 2ATOA 3IOQA 1AU4A 1Q6KA 2PBHA 1VJVA 2G6DA 2AIMA 3ERVA 1CB5A 5F02A 1K3BB 4X6HA 3S3QA 4BQVA 1PPNA 1NPZA 2R9OA 1Y4HA 1CJLA 1KFXL 3HHIA 1PPPA 8PCHA 1YT7A 1CSBB 2G8JA 2JQFR 2PADA 4QRGA 1AIMA 2DC7A 2NQAA 4QRXA 1F29A 4N79A 4CDEB 4DMYA 1PBHA 3LTWA 3N3KA 1AECA 2E02A 2DCBA 5CHVA 3B79A 2ACTA 3WXGA 4W5BA 1BY8A 4RY2A 2R6NA 3QSDA 7PCKA 3H7DA 1M6DA 1W4TA 3IHPA 4C5PA 2AS8A 5CVNB 2OP3A 3E1ZB 1EWMA 2DCCA 3KKUA 4BS6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1G A;  4PP2 E;  2AUX A;  2OZ2 A;  4AXM A;  1ITO A;  1MIR A;  1ATK A;  1NL6 A;  1YK8 A;  4N4Z A;  6PAD A;  3P5U A;  3V6E A;  2OUL A;  1HUC B;  1U9W A;  1SP4 B;  1Y08 A;  4Q8H A;  1CQD A;  1U5I A;  2E03 A;  2B1N A;  5JH3 A;  1PAD A;  1PIP A;  3MTN A;  3KW9 A;  3NHE A;  2O6X A;  2HH5 A;  2F7D A;  3AI8 A;  2YJ9 A;  3D6S A;  3OVX A;  1YAL A;  4K7C A;  1AU2 A;  3HHA A;  4AXL A;  1AYU A;  1YK7 A;  3K24 A;  4X6I A;  9PAP A;  3KWZ A;  4ZUX U;  3CH2 X;  2P86 A;  1KHQ A;  2FT2 A;  5EGW A;  1FH0 A;  1YVB A;  1NLJ A;  4X6J A;  2GHU A;  1EWO A;  2Y5B A;  1EWP A;  3V6C A;  2AU1 A;  2G8E A;  2AYO A;  2DJG B;  4Q8G A;  3KX1 A;  1TLO A;  3QT4 A;  2NQD B;  1NQC A;  3H8B A;  3BWK A;  3LFY A;  2G7Y A;  2HD5 A;  3P5X A;  2WBF X;  1QOL A;  2DZZ A;  2XU3 A;  1ME3 A;  3N4C A;  1GMY A;  1CS8 A;  1ME4 A;  2BDZ A;  1ZIV A;  1PPO A;  1MHW A;  3I3T A;  4W4U A;  1NB5 A;  3USV A;  1JQP A;  4MZS A;  4YYV A;  1TL9 A;  4XR7 A;  5CVO B;  3CBJ A;  1S4V A;  2DJF B;  3TNX A;  2HHN A;  3M99 A;  4YVA A;  4PI3 A;  1U9V A;  1POP A;  2FRQ A;  2DZY A;  2B1M A;  2HXZ A;  3O1G A;  4YYQ A;  3CH3 X;  3QJ3 A;  1SNK A;  2FUD A;  1CVZ A;  4YV8 A;  1XKG A;  2R9N A;  3P5V A;  4DMX A;  1PE6 A;  1U9X A;  1QDQ A;  2C0Y A;  5J94 A;  3PBH A;  1CV8 A;  1QXP A;  3IUT A;  1MEM A;  5JA7 A;  4I05 A;  2VHF A;  2BDL A;  3RVW A;  2YJC A;  3K9M A;  2ARY A;  3H8C A;  4P6G A;  3PW3 A;  4BPV A;  3HD3 A;  4I07 A;  2H7J A;  3P5W A;  1BQI A;  1F2C A;  3LXS A;  3O0U A;  3MHS A;  1DF0 A;  4G54 A;  2P0R A;  2NQG A;  1AU3 A;  2E01 A;  3IMA A;  1ZCM A;  3PNR A;  4BS5 A;  4OEM A;  1EWL A;  4PAD A;  4CDD B;  3KWB X;  4YYU A;  4PP1 A;  2FO5 A;  5PAD A;  3H6S A;  4MSX A;  3N3G A;  5K16 A;  1A6R A;  2NQI A;  3IEJ A;  2JQG R;  2XU1 A;  3PDF A;  2DCA A;  4CDC B;  2P7U A;  4HWY A;  2FQ9 A;  2GFO A;  5FPW A;  3BOW A;  4QRV A;  3BPF A;  1PXV A;  1AU0 A;  2CIO A;  1AYV A;  2IPP B;  5A24 A;  2DC8 A;  3IV2 A;  2E00 A;  4WA6 A;  3RVX A;  1GEC E;  2IBI A;  1TU6 A;  2YJB A;  5CVM A;  2R9C A;  2FYE A;  2R9F A;  1ICF A;  3KSE A;  2DC6 A;  3BPM A;  4P6E A;  4QH6 A;  3BC3 A;  1GLO A;  1BP4 A;  2XU5 A;  2DC9 A;  2XU4 A;  4N8W A;  3CBK A;  1GCB A;  2DCD A;  4FIP A;  3OF9 A;  4XUI A;  4W5C A;  1PCI A;  4FK5 A;  3F5V A;  1KXR A;  3HWN A;  1BGO A;  2PNS A;  1MEG A;  1VSN A;  3I06 A;  1MS6 A;  1THE A;  2VHS A;  1KHP A;  2AUZ A;  2R9M A;  2AYN A;  3RVV A;  1X9Y A;  2YJ2 A;  4YYW A;  3OF8 A;  2PRE A;  1CPJ A;  2AVW A;  1IWD A;  2Y6E A;  1CTE A;  1STF E;  3MHH A;  4QBB A;  4MZO A;  4I04 A;  4CDF B;  2FTD A;  1F2A A;  3H89 A;  1AYW A;  2YJ8 A;  3K8U A;  1F2B A;  3KFQ A;  4YYR A;  1PPD A;  3WXE A;  3U8E A;  2FRA A;  1O0E A;  5CHT A;  4YYS A;  3WXF A;  3C9E A;  3OIS A;  1NB3 A;  1U9Q X;  5EF4 A;  3S3R A;  2CB5 A;  3GCB A;  4BSQ A;  3BCN A;  4FJC A;  1DEU A;  1MDW A;  4KLB A;  4CZW A;  3OVZ A;  1KFU L;  1EF7 A;  3DF0 A;  3MOR A;  3F75 A;  4OEL A;  3ZUA A;  1QMY A;  2ATO A;  3IOQ A;  1AU4 A;  1Q6K A;  2PBH A;  1VJV A;  2G6D A;  2AIM A;  3ERV A;  1CB5 A;  5F02 A;  1K3B B;  4X6H A;  3S3Q A;  4BQV A;  1PPN A;  1NPZ A;  2R9O A;  1Y4H A;  1CJL A;  1KFX L;  3HHI A;  1PPP A;  8PCH A;  1YT7 A;  1CSB B;  2G8J A;  2JQF R;  2PAD A;  4QRG A;  1AIM A;  2DC7 A;  2NQA A;  4QRX A;  1F29 A;  4N79 A;  4CDE B;  4DMY A;  1PBH A;  3N3K A;  1AEC A;  2E02 A;  2DCB A;  5CHV A;  3B79 A;  2ACT A;  3WXG A;  4W5B A;  1BY8 A;  4RY2 A;  2R6N A;  3QSD A;  7PCK A;  3H7D A;  1M6D A;  3IHP A;  2AS8 A;  5CVN B;  2OP3 A;  3E1Z B;  1EWM A;  2DCC A;  3KKU A;  4BS6 A; 
#chains in the Genus database with same CATH topology
 2F1G A;  4PP2 E;  2AUX A;  4OVZ A;  2OZ2 A;  4AXM A;  1ITO A;  1MIR A;  1ATK A;  1NL6 A;  1YK8 A;  4N4Z A;  6PAD A;  3P5U A;  3V6E A;  2OUL A;  1HUC B;  4D8E A;  1UKF A;  1U9W A;  1SP4 B;  3BY4 A;  1Y08 A;  4Q8H A;  1CQD A;  1U5I A;  2E03 A;  2B1N A;  5JH3 A;  1PVJ A;  1PAD A;  1PIP A;  3MTN A;  4A5U A;  3KW9 A;  2HWK A;  3NHE A;  2O6X A;  2HH5 A;  2F7D A;  3AI8 A;  5E6J A;  2YJ9 A;  3D6S A;  3OVX A;  1YAL A;  4REZ A;  4K7C A;  1AU2 A;  4MM3 B;  3HHA A;  4AXL A;  1AYU A;  1YK7 A;  3K24 A;  4X6I A;  9PAP A;  4BOQ A;  3KWZ A;  4ZUX U;  3CH2 X;  2P86 A;  1KHQ A;  2FT2 A;  5EGW A;  1FH0 A;  3MJ5 A;  4BOS A;  1YVB A;  3B21 A;  2JTC A;  1NLJ A;  4RF0 A;  4X6J A;  2GHU A;  3MP2 A;  1EWO A;  2Y5B A;  1EWP A;  3V6C A;  2AU1 A;  2G8E A;  2AYO A;  2DJG B;  4Q8G A;  3KX1 A;  1TLO A;  3QT4 A;  2NQD B;  1NQC A;  3H8B A;  3BWK A;  4GUA A;  3LFY A;  2G7Y A;  2HD5 A;  3P5X A;  2WBF X;  4P16 A;  1QOL A;  4RNA A;  2DZZ A;  2XU3 A;  1ME3 A;  3N4C A;  1GMY A;  1CS8 A;  4RKX A;  1ME4 A;  2BDZ A;  2J7Q A;  4D8B A;  1ZIV A;  1PPO A;  1MHW A;  3I3T A;  4W4U A;  1NB5 A;  3USV A;  1JQP A;  4MZS A;  4YYV A;  1TL9 A;  4XR7 A;  5CVO B;  3CBJ A;  1S4V A;  2DJF B;  3TNX A;  2HHN A;  3M99 A;  3E9S A;  4YVA A;  4PI3 A;  1U9V A;  2BTW B;  1POP A;  2FRQ A;  2DZY A;  2B1M A;  2HXZ A;  3O1G A;  4YYQ A;  3CH3 X;  3QJ3 A;  1SNK A;  2FUD A;  1CVZ A;  4YV8 A;  3IFU A;  1XKG A;  2R9N A;  3P5V A;  4DMX A;  1PE6 A;  1U9X A;  1QDQ A;  3PSE A;  2C0Y A;  5J94 A;  3PBH A;  1CV8 A;  1QXP A;  3IUT A;  1MEM A;  5JA7 A;  4I05 A;  4IUM A;  2VHF A;  2BDL A;  3RVW A;  2YJC A;  1DKI A;  3K9M A;  2ARY A;  3H8C A;  4P6G A;  3PW3 A;  4BPV A;  3HD3 A;  4I07 A;  2H7J A;  3P5W A;  1BQI A;  1F2C A;  4D8I A;  4IP3 A;  3LXS A;  3O0U A;  3MHS A;  1DF0 A;  4G54 A;  2P0R A;  2NQG A;  1AU3 A;  2E01 A;  3IMA A;  1ZCM A;  3PNR A;  4BS5 A;  4OEM A;  1EWL A;  4PAD A;  4CDD B;  3KWB X;  4YYU A;  4PP1 A;  2FO5 A;  4OVZ B;  5PAD A;  3H6S A;  4MSX A;  3N3G A;  5K16 A;  1A6R A;  2NQI A;  3PHX A;  3IEJ A;  2JQG R;  2XU1 A;  3PDF A;  2DCA A;  2DOS A;  2JRI A;  2P7U A;  4CDC B;  4HWY A;  2FQ9 A;  2GFO A;  5FPW A;  3BOW A;  4QRV A;  3BPF A;  1PXV A;  1AU0 A;  2CIO A;  1AYV A;  4MI7 A;  2IPP B;  4M0W A;  5A24 A;  2DC8 A;  3IV2 A;  2E00 A;  4WA6 A;  2UZJ A;  3RVX A;  1GEC E;  2IBI A;  4R3D A;  1TU6 A;  2YJB A;  5CVM A;  2R9C A;  2FYE A;  2R9F A;  1ICF A;  3KSE A;  2BU3 A;  2FE8 A;  2DC6 A;  4BOP A;  3BPM A;  4P6E A;  4QH6 A;  3BC3 A;  1GLO A;  1BP4 A;  2XU5 A;  2Z84 A;  2DC9 A;  1YZB A;  2XU4 A;  4N8W A;  4WUR A;  3CBK A;  1GCB A;  2DCD A;  4FIP A;  2J7Q C;  3OF9 A;  4RF1 A;  2AGA A;  4XUI A;  4W5C A;  1PCI A;  4FK5 A;  3F5V A;  1KXR A;  3HWN A;  3PRP A;  1BGO A;  2PNS A;  1MEG A;  1VSN A;  3I06 A;  1MS6 A;  1THE A;  2VHS A;  1KHP A;  2AUZ A;  2R9M A;  4PT5 A;  2AYN A;  3RVV A;  1X9Y A;  2YJ2 A;  4YYW A;  3OF8 A;  3OQC A;  2PRE A;  1CPJ A;  4HXD B;  2AVW A;  1IWD A;  2Y6E A;  3O65 A;  1CTE A;  3PHU A;  1STF E;  3C0R A;  3MHH A;  4QBB A;  3PHW A;  5EZS A;  4MZO A;  4I04 A;  4CDF B;  2FTD A;  1F2A A;  3H89 A;  1AYW A;  2YJ8 A;  3K8U A;  1F2B A;  3KFQ A;  3TRK A;  4YYR A;  1PPD A;  4XZX A;  3BB7 A;  3WXE A;  3U8E A;  2FRA A;  1O0E A;  5CHT A;  4YYS A;  3WXF A;  3C9E A;  3ZNH A;  3OIS A;  1NB3 A;  1U9Q X;  5EF4 A;  3S3R A;  2CB5 A;  3GCB A;  4BSQ A;  3BCN A;  4FJC A;  1DEU A;  1MDW A;  3PRM A;  4KLB A;  3MTV A;  4CZW A;  3OVZ A;  1KFU L;  1EF7 A;  3DF0 A;  3MOR A;  3F75 A;  4OEL A;  3ZUA A;  1QMY A;  2ATO A;  3PT2 A;  3IOQ A;  4OW0 A;  1AU4 A;  1Q6K A;  2PBH A;  1VJV A;  4BOU A;  2BTW A;  2G6D A;  2AIM A;  5KO3 A;  3ERV A;  1CB5 A;  5F02 A;  1K3B B;  4X6H A;  3S3Q A;  4BQV A;  1PPN A;  1NPZ A;  2R9O A;  1Y4H A;  1CJL A;  1KFX L;  3HHI A;  1PPP A;  8PCH A;  1YT7 A;  5JZE A;  1CSB B;  2G8J A;  2JQF R;  2PAD A;  4QRG A;  1AIM A;  2DC7 A;  2NQA A;  4QRX A;  3W30 A;  1F29 A;  4N79 A;  3TMP A;  4CDE B;  5EZQ A;  4DMY A;  3BBA A;  1PBH A;  3RNV A;  3N3K A;  1AEC A;  2E02 A;  2DCB A;  5CHV A;  3B79 A;  2ACT A;  3WXG A;  4W5B A;  1BY8 A;  4RY2 A;  2R6N A;  4ZTB A;  3QSD A;  7PCK A;  3H7D A;  1M6D A;  3W31 A;  3IHP A;  2AS8 A;  5CVN B;  2OP3 A;  3E1Z B;  1EWM A;  2DCC A;  4BOZ A;  3KKU A;  4BS6 A; 
#chains in the Genus database with same CATH homology
 2F1G A;  4PP2 E;  2AUX A;  2OZ2 A;  4AXM A;  1ITO A;  1MIR A;  1ATK A;  1NL6 A;  1YK8 A;  4N4Z A;  6PAD A;  3P5U A;  3V6E A;  2OUL A;  1HUC B;  4B55 A;  1U9W A;  1SP4 B;  1Y08 A;  4Q8H A;  1CQD A;  1U5I A;  2E03 A;  2B1N A;  5JH3 A;  1PAD A;  1PIP A;  3MTN A;  3KW9 A;  3NHE A;  2O6X A;  2HH5 A;  2F7D A;  3AI8 A;  2YJ9 A;  3D6S A;  3OVX A;  1YAL A;  2VFB A;  4K7C A;  1AU2 A;  3HHA A;  4AXL A;  1AYU A;  1YK7 A;  3K24 A;  4X6I A;  9PAP A;  1GX3 A;  3KWZ A;  4ZUX U;  3CH2 X;  2P86 A;  1KHQ A;  2FT2 A;  5EGW A;  1FH0 A;  1YVB A;  1NLJ A;  4X6J A;  2GHU A;  1EWO A;  2Y5B A;  4GUZ A;  1EWP A;  3V6C A;  2AU1 A;  2G8E A;  2AYO A;  2DJG B;  4Q8G A;  3KX1 A;  1TLO A;  3QT4 A;  2NQD B;  1NQC A;  3H8B A;  3BWK A;  3LFY A;  2G7Y A;  2HD5 A;  3P5X A;  2WBF X;  1QOL A;  2DZZ A;  2XU3 A;  1ME3 A;  3N4C A;  1GMY A;  1CS8 A;  1ME4 A;  2BDZ A;  1ZIV A;  1PPO A;  1MHW A;  3I3T A;  4W4U A;  1NB5 A;  3USV A;  1JQP A;  4MZS A;  4YYV A;  1TL9 A;  4XR7 A;  5CVO B;  3CBJ A;  1S4V A;  2DJF B;  3TNX A;  2HHN A;  3M99 A;  4YVA A;  4PI3 A;  1U9V A;  1POP A;  2FRQ A;  2DZY A;  2B1M A;  2HXZ A;  3O1G A;  4YYQ A;  3CH3 X;  3QJ3 A;  1SNK A;  2FUD A;  1CVZ A;  4YV8 A;  1XKG A;  2R9N A;  3P5V A;  4DMX A;  1PE6 A;  1U9X A;  1W5R A;  1QDQ A;  2C0Y A;  5J94 A;  3PBH A;  1CV8 A;  1QXP A;  3IUT A;  1MEM A;  5JA7 A;  4I05 A;  2VHF A;  2BDL A;  3RVW A;  2YJC A;  3K9M A;  2ARY A;  3H8C A;  4P6G A;  3PW3 A;  4BPV A;  3HD3 A;  4I07 A;  2BSZ A;  3D9W A;  2H7J A;  3P5W A;  1BQI A;  1F2C A;  4BGF A;  3LXS A;  3O0U A;  3MHS A;  1DF0 A;  4G54 A;  2P0R A;  2NQG A;  1AU3 A;  2E01 A;  3IMA A;  1ZCM A;  3PNR A;  4BS5 A;  4OEM A;  1EWL A;  4PAD A;  4CDD B;  3KWB X;  4YYU A;  4PP1 A;  2FO5 A;  5PAD A;  3H6S A;  4MSX A;  3N3G A;  5K16 A;  1A6R A;  2NQI A;  3IEJ A;  2JQG R;  2XU1 A;  3PDF A;  2DCA A;  4CDC B;  2P7U A;  4HWY A;  2FQ9 A;  2GFO A;  5FPW A;  3BOW A;  4QRV A;  3BPF A;  1PXV A;  1AU0 A;  2CIO A;  1AYV A;  2IPP B;  5A24 A;  2DC8 A;  3IV2 A;  2E00 A;  4WA6 A;  3RVX A;  1GEC E;  2IBI A;  1TU6 A;  2YJB A;  5CVM A;  2R9C A;  2FYE A;  2R9F A;  1ICF A;  3KSE A;  2DC6 A;  3BPM A;  4P6E A;  4QH6 A;  3BC3 A;  1GLO A;  1BP4 A;  2XU5 A;  2DC9 A;  2XU4 A;  4N8W A;  3CBK A;  1GCB A;  2DCD A;  4FIP A;  3OF9 A;  4XUI A;  4W5C A;  1PCI A;  4FK5 A;  3F5V A;  1KXR A;  3HWN A;  1BGO A;  2PNS A;  1MEG A;  1VSN A;  3I06 A;  1MS6 A;  1THE A;  2VHS A;  1KHP A;  2AUZ A;  2R9M A;  2AYN A;  3RVV A;  1X9Y A;  2YJ2 A;  4YYW A;  3OF8 A;  2PRE A;  1CPJ A;  2AVW A;  1IWD A;  2Y6E A;  1CTE A;  1E2T A;  1STF E;  4NV8 A;  3MHH A;  4QBB A;  4MZO A;  4I04 A;  4CDF B;  2FTD A;  1F2A A;  3H89 A;  4NV7 A;  1AYW A;  2YJ8 A;  3K8U A;  1F2B A;  3KFQ A;  4YYR A;  1PPD A;  3WXE A;  3U8E A;  2FRA A;  1O0E A;  5CHT A;  4YYS A;  3WXF A;  3C9E A;  3OIS A;  1NB3 A;  1U9Q X;  5EF4 A;  3S3R A;  2CB5 A;  3GCB A;  4BSQ A;  3BCN A;  4FJC A;  1W6F A;  1DEU A;  1MDW A;  4KLB A;  4CZW A;  3OVZ A;  1KFU L;  2VFC A;  1EF7 A;  3DF0 A;  3MOR A;  3F75 A;  4OEL A;  3ZUA A;  1QMY A;  2ATO A;  3IOQ A;  1AU4 A;  1Q6K A;  2PBH A;  1VJV A;  2G6D A;  2AIM A;  3ERV A;  1CB5 A;  5F02 A;  1K3B B;  4X6H A;  3S3Q A;  4BQV A;  1PPN A;  1NPZ A;  2R9O A;  1Y4H A;  1CJL A;  1KFX L;  3HHI A;  1PPP A;  8PCH A;  1YT7 A;  1CSB B;  2G8J A;  2JQF R;  2PAD A;  4QRG A;  1AIM A;  2DC7 A;  2NQA A;  4QRX A;  1F29 A;  4N79 A;  4CDE B;  4DMY A;  1PBH A;  3LTW A;  3N3K A;  1AEC A;  2E02 A;  2DCB A;  5CHV A;  3B79 A;  2ACT A;  3WXG A;  4W5B A;  1BY8 A;  4RY2 A;  2R6N A;  3QSD A;  7PCK A;  3H7D A;  1M6D A;  1W4T A;  3IHP A;  4C5P A;  2AS8 A;  5CVN B;  2OP3 A;  3E1Z B;  1EWM A;  2DCC A;  3KKU A;  4BS6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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