2DC7A

X-ray crystal structure analysis of bovine spleen cathepsin b-ca042 complex
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
253
structure length
251
Chain Sequence
LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMPCT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
rcsb
molecule tags Hydrolase
molecule keywords CATHEPSIN B
total genus 74
structure length 251
sequence length 253
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2005-12-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2dc7A00
3QJ3A 1PE6A 1AU3A 4XUIA 3BWKA 1MHWA 2E00A 5J94A 4RY2A 3USVA 3N3GA 3H8CA 4YYVA 3IHPA 1SNKA 3HWNA 3OVXA 1PCIA 1AIMA 3IUTA 1SP4B 5F02A 1CS8A 2IPPB 4QBBA 3C9EA 4PP1A 3CBJA 2JQFR 2G7YA 2GFOA 5EGWA 1GLOA 4I07A 2OULA 3K9MA 4QRXA 3N4CA 9PAPA 2ATOA 4X6HA 1BGOA 2DJGB 1XKGA 1ICFA 2R9NA 1NL6A 3F5VA 2HHNA 3PBHA 3BPMA 4CDDB 1MDWA 1PPDA 4QRVA 2AUXA 1PXVA 1CJLA 3MHHA 3K8UA 1DF0A 2DC6A 2FQ9A 1CTEA 1F2CA 2E01A 2AS8A 4YYQA 4CDEB 1CPJA 1ZIVA 1YT7A 2CIOA 2R9OA 5PADA 1HUCB 1EWOA 3PDFA 3O1GA 1IWDA 1DEUA 4YYSA 1VSNA 2DC8A 1MEGA 3IMAA 2PREA 4QRGA 3KKUA 2F1GA 3MHSA 1EWMA 2NQIA 4MSXA 5FPWA 2XU4A 3E1ZB 3PW3A 1U5IA 2AVWA 3M99A 1TL9A 1U9XA 2YJBA 1FH0A 1GCBA 3KFQA 1PPNA 4XR7A 3KW9A 2WBFX 2B1NA 1POPA 2FO5A 4OELA 4YYUA 4N4ZA 1MS6A 3H6SA 2C0YA 4PADA 2FRAA 3CBKA 4CDCB 1CQDA 3NHEA 3WXFA 3ERVA 1AYVA 4FK5A 1CV8A 3S3QA 4BS5A 4MZOA 2AIMA 1PADA 2E03A 4AXMA 1BY8A 4WA6A 3WXEA 3P5UA 4YVAA 4X6IA 3LFYA 2HH5A 4BQVA 2VHFA 4YV8A 2AYNA 5JA7A 2ARYA 4FJCA 1QMYA 3IOQA 2F7DA 2OP3A 1ZCMA 5JH3A 1O0EA 1AU0A 2GHUA 3DF0A 3PNRA 2R9FA 4YYWA 3RVWA 2HXZA 3OF9A 1S4VA 3HHIA 2CB5A 4X6JA 2B1MA 4YYRA 3N3KA 2Y6EA 2O6XA 2DCBA 2FUDA 2DJFB 2P86A 1F2AA 3F75A 2DZYA 4G54A 2P0RA 1QDQA 2DC7A 2DZZA 3H7DA 3IEJA 1Y08A 1EWPA 2YJCA 1ATKA 2E02A 4AXLA 2FYEA 1BQIA 1PIPA 1YVBA 1KFUL 1NB3A 2H7JA 1BP4A 2OZ2A 2YJ9A 4Q8GA 3S3RA 2ACTA 5CVOB 1F2BA 1YALA 2Y5BA 1X9YA 3P5XA 1PBHA 3IV2A 3MORA 1GMYA 1THEA 2VHSA 3QT4A 1PPOA 4FIPA 1CB5A 2YJ8A 3OVZA 4CDFB 1U9WA 2XU1A 4P6GA 4K7CA 3CH3X 3GCBA 3I3TA 1EWLA 1Q6KA 4DMYA 1AYWA 3BCNA 4BSQA 3BPFA 2FTDA 5A24A 1F29A 3BC3A 1ME3A 1NPZA 4PP2E 1U9QX 2R6NA 2P7UA 7PCKA 3V6CA 5CVNB 4BS6A 1AYUA 1MEMA 4MZSA 4BPVA 2NQDB 5EF4A 4W5CA 4I04A 3D6SA 3HHAA 6PADA 3KX1A 3I06A 2DCDA 1U9VA 4I05A 5CVMA 2PBHA 4KLBA 2DCAA 2BDZA 1Y4HA 3H8BA 1VJVA 2BDLA 2G8JA 2IBIA 3V6EA 3MTNA 2YJ2A 1EF7A 3OISA 1CSBB 1QXPA 1MIRA 1NLJA 1AECA 1KHPA 1ITOA 4W4UA 2R9CA 4QH6A 4DMXA 1M6DA 1YK8A 1AU2A 1KXRA 3P5WA 3P5VA 2DC9A 3RVVA 1NB5A 2PADA 1CVZA 1JQPA 2HD5A 4HWYA 2G8EA 4N79A 1ME4A 2PNSA 1STFE 3U8EA 1K3BB 3K24A 3RVXA 5CHTA 3KSEA 2DCCA 2R9MA 4OEMA 2AUZA 1YK7A 4CZWA 3KWBX 1QOLA 3KWZA 4N8WA 3TNXA 3LXSA 2NQAA 2FT2A 3ZUAA 1GECE 3OF8A 3O0UA 1NQCA 1A6RA 4Q8HA 2FRQA 3CH2X 3B79A 3WXGA 4ZUXU 1KHQA 2G6DA 1AU4A 1PPPA 2AYOA 3QSDA 4P6EA 5CHVA 1KFXL 2NQGA 2AU1A 3BOWA 4W5BA 2XU3A 3H89A 2XU5A 4PI3A 3HD3A 5K16A 1TLOA 2JQGR 3AI8A 8PCHA 1TU6A
chains in the Genus database with same CATH superfamily
3QJ3A 1PE6A 1AU3A 4XUIA 3E9SA 3BWKA 3C0RA 4RF1A 1MHWA 2E00A 5J94A 4RY2A 3USVA 3N3GA 3H8CA 4YYVA 3IHPA 1SNKA 3HWNA 3OVXA 1PCIA 2Z84A 1AIMA 3IUTA 3W30A 1SP4B 5F02A 4XZXA 1CS8A 2IPPB 4QBBA 3C9EA 4PP1A 3CBJA 2JQFR 2G7YA 2GFOA 5EGWA 1GLOA 4I07A 2OULA 3PHXA 3K9MA 4QRXA 3N4CA 9PAPA 2ATOA 4X6HA 1BGOA 2DJGB 1XKGA 1ICFA 3PHWA 2R9NA 1NL6A 4D8BA 3F5VA 2HHNA 3PBHA 3BPMA 4CDDB 1MDWA 1PPDA 4QRVA 2AUXA 1PXVA 1CJLA 3MHHA 3K8UA 1DF0A 2DC6A 2FQ9A 1CTEA 1F2CA 2E01A 2AS8A 4YYQA 4CDEB 1CPJA 1DKIA 1ZIVA 1YT7A 4GUAA 4REZA 2CIOA 2R9OA 5PADA 1HUCB 3BBAA 1EWOA 1YZBA 3PDFA 2J7QA 3O1GA 1IWDA 1DEUA 4YYSA 1VSNA 2DC8A 1MEGA 3IMAA 2PREA 4QRGA 3KKUA 2F1GA 3MHSA 1EWMA 2DOSA 2NQIA 4MSXA 5FPWA 2XU4A 3E1ZB 3PW3A 1U5IA 2AVWA 3M99A 3ZNHA 1TL9A 4BOPA 1U9XA 2YJBA 3TMPA 3W31A 1FH0A 1GCBA 3KFQA 1PPNA 4XR7A 2AGAA 2BTWA 3KW9A 2WBFX 4RNAA 2B1NA 1POPA 2FO5A 4OELA 4YYUA 4N4ZA 4OW0A 3IFUA 4D8EA 1MS6A 3H6SA 1UKFA 2C0YA 3OQCA 4PADA 2FRAA 3CBKA 4CDCB 1CQDA 3NHEA 3WXFA 3ERVA 1AYVA 4FK5A 1CV8A 3S3QA 4BS5A 4MZOA 2AIMA 1PADA 2E03A 4AXMA 1BY8A 4BOZA 4WA6A 4BOSA 3WXEA 3P5UA 4YVAA 4X6IA 3LFYA 2HH5A 4HXDB 4BQVA 2VHFA 4OVZA 4YV8A 2AYNA 5JA7A 2ARYA 4FJCA 1QMYA 3IOQA 2F7DA 2OP3A 3PSEA 1ZCMA 5JH3A 1O0EA 1AU0A 2GHUA 3DF0A 3PNRA 2R9FA 5EZQA 4YYWA 3RVWA 2HXZA 3OF9A 2JTCA 1S4VA 3HHIA 2CB5A 4X6JA 2B1MA 4YYRA 5EZSA 3N3KA 3TRKA 2Y6EA 2O6XA 2DCBA 2FUDA 2DJFB 2P86A 1F2AA 1PVJA 3F75A 2DZYA 4G54A 2P0RA 1QDQA 2DC7A 2DZZA 3H7DA 3IEJA 4RF0A 1Y08A 4MI7A 1EWPA 2YJCA 1ATKA 2E02A 4AXLA 2FYEA 1BQIA 1PIPA 1YVBA 1KFUL 1NB3A 2H7JA 1BP4A 2OZ2A 2YJ9A 3RNVA 4Q8GA 3S3RA 2ACTA 5CVOB 1F2BA 1YALA 4IUMA 2Y5BA 1X9YA 3P5XA 2J7QC 1PBHA 3IV2A 3MORA 1GMYA 1THEA 2VHSA 3QT4A 1PPOA 4FIPA 1CB5A 2YJ8A 4MM3B 3OVZA 4CDFB 1U9WA 2XU1A 4P6GA 4K7CA 3CH3X 4P16A 3GCBA 3I3TA 1EWLA 1Q6KA 4DMYA 1AYWA 3BCNA 4A5UA 4BSQA 3BPFA 4R3DA 2FTDA 5A24A 1F29A 3BC3A 4M0WA 1ME3A 1NPZA 4WURA 4PP2E 1U9QX 3MTVA 2R6NA 2P7UA 7PCKA 3V6CA 2JRIA 5CVNB 4BS6A 1AYUA 1MEMA 4MZSA 4BPVA 2BU3A 2NQDB 4BOUA 5E6JA 5EF4A 4W5CA 4I04A 3D6SA 3HHAA 6PADA 3KX1A 3I06A 2DCDA 3PRPA 1U9VA 3MJ5A 4I05A 5CVMA 4D8IA 2PBHA 4KLBA 2BTWB 2DCAA 2BDZA 1Y4HA 3H8BA 1VJVA 3B21A 2BDLA 2G8JA 2IBIA 3V6EA 3MTNA 2YJ2A 1EF7A 3OISA 5JZEA 1CSBB 1QXPA 1MIRA 3PT2A 1NLJA 2FE8A 1AECA 3MP2A 1KHPA 1ITOA 2UZJA 4W4UA 3PRMA 2R9CA 4QH6A 4DMXA 1M6DA 1YK8A 1AU2A 1KXRA 3P5WA 3P5VA 2DC9A 3RVVA 2HWKA 1NB5A 2PADA 1CVZA 1JQPA 2HD5A 4HWYA 4IP3A 3PHUA 2G8EA 4N79A 1ME4A 2PNSA 1STFE 3U8EA 4BOQA 5KO3A 1K3BB 3K24A 3RVXA 5CHTA 3KSEA 2DCCA 2R9MA 4OEMA 2AUZA 1YK7A 4OVZB 4CZWA 3KWBX 1QOLA 3KWZA 4N8WA 3BY4A 4ZTBA 3TNXA 3LXSA 2NQAA 2FT2A 3ZUAA 1GECE 3OF8A 3O0UA 1NQCA 1A6RA 4Q8HA 2FRQA 3CH2X 3B79A 3WXGA 4ZUXU 1KHQA 3O65A 2G6DA 1AU4A 1PPPA 2AYOA 3QSDA 4P6EA 5CHVA 1KFXL 4RKXA 3BB7A 2NQGA 2AU1A 3BOWA 4W5BA 2XU3A 3H89A 2XU5A 4PI3A 3HD3A 4PT5A 5K16A 1TLOA 2JQGR 3AI8A 8PCHA 1TU6A
chains in the Genus database with same CATH topology
3QJ3A 1PE6A 1AU3A 4XUIA 3BWKA 1MHWA 3D9WA 2E00A 5J94A 4RY2A 3USVA 3N3GA 3H8CA 4YYVA 3IHPA 1SNKA 3HWNA 3OVXA 1PCIA 1AIMA 3IUTA 1SP4B 1E2TA 5F02A 1CS8A 2IPPB 4QBBA 3C9EA 4PP1A 3CBJA 2JQFR 2G7YA 2GFOA 5EGWA 1GLOA 4I07A 2OULA 3K9MA 2BSZA 4QRXA 3N4CA 9PAPA 2ATOA 4X6HA 1BGOA 2DJGB 1XKGA 1ICFA 2R9NA 1NL6A 3F5VA 2HHNA 3PBHA 3BPMA 4CDDB 1MDWA 1PPDA 4QRVA 2AUXA 1PXVA 1CJLA 3MHHA 3K8UA 1DF0A 2DC6A 2FQ9A 1CTEA 1F2CA 2E01A 2AS8A 4YYQA 4CDEB 1CPJA 1ZIVA 1YT7A 2CIOA 2R9OA 5PADA 1HUCB 1EWOA 3PDFA 3O1GA 1IWDA 1DEUA 4YYSA 1VSNA 2DC8A 1MEGA 3IMAA 2PREA 4QRGA 3KKUA 2F1GA 3MHSA 4NV7A 1EWMA 2NQIA 4MSXA 5FPWA 2XU4A 3E1ZB 3PW3A 1U5IA 2AVWA 3M99A 1TL9A 1U9XA 2YJBA 1FH0A 1GCBA 3KFQA 1PPNA 4XR7A 3KW9A 2WBFX 2B1NA 1POPA 2FO5A 4OELA 4YYUA 4N4ZA 1MS6A 3H6SA 2C0YA 1W6FA 4PADA 2FRAA 3CBKA 4CDCB 1CQDA 3NHEA 3WXFA 3ERVA 1AYVA 4FK5A 1CV8A 3S3QA 4BS5A 4MZOA 2AIMA 1PADA 2E03A 4AXMA 1BY8A 4WA6A 3WXEA 3P5UA 4YVAA 4X6IA 3LFYA 2HH5A 4BQVA 4GUZA 2VHFA 4YV8A 2AYNA 5JA7A 2ARYA 4FJCA 1QMYA 3IOQA 2F7DA 2OP3A 1ZCMA 5JH3A 1O0EA 1W5RA 1AU0A 4B55A 2GHUA 3DF0A 3PNRA 2R9FA 4YYWA 3RVWA 2HXZA 3OF9A 1S4VA 3HHIA 2CB5A 4X6JA 2B1MA 4YYRA 3LTWA 3N3KA 2Y6EA 2O6XA 2DCBA 2FUDA 2DJFB 2P86A 1F2AA 3F75A 2DZYA 4G54A 2P0RA 1QDQA 2DC7A 2DZZA 3H7DA 3IEJA 1Y08A 1EWPA 2YJCA 1ATKA 2E02A 4AXLA 2FYEA 1BQIA 1PIPA 1YVBA 1KFUL 1NB3A 2H7JA 1BP4A 2OZ2A 2YJ9A 4Q8GA 3S3RA 2ACTA 5CVOB 1F2BA 1YALA 2Y5BA 1X9YA 3P5XA 1PBHA 3IV2A 3MORA 1GMYA 1THEA 2VHSA 3QT4A 1PPOA 4FIPA 4BGFA 1CB5A 2YJ8A 3OVZA 4CDFB 1U9WA 2XU1A 4P6GA 4K7CA 3CH3X 3GCBA 3I3TA 1EWLA 1Q6KA 4DMYA 1AYWA 3BCNA 4BSQA 3BPFA 2FTDA 5A24A 1F29A 3BC3A 1ME3A 1NPZA 4PP2E 1U9QX 2R6NA 2P7UA 7PCKA 3V6CA 5CVNB 4BS6A 1AYUA 1MEMA 4MZSA 4BPVA 2NQDB 5EF4A 4W5CA 4I04A 3D6SA 3HHAA 6PADA 3KX1A 3I06A 2DCDA 1U9VA 4I05A 5CVMA 4C5PA 2PBHA 4KLBA 4NV8A 2DCAA 2BDZA 1Y4HA 3H8BA 1VJVA 2BDLA 2G8JA 2IBIA 3V6EA 3MTNA 2YJ2A 1EF7A 3OISA 1CSBB 1QXPA 1MIRA 1NLJA 1AECA 1KHPA 1ITOA 4W4UA 2R9CA 4QH6A 4DMXA 1M6DA 1YK8A 1AU2A 1KXRA 3P5WA 3P5VA 2DC9A 3RVVA 1GX3A 1NB5A 2PADA 1CVZA 1JQPA 2HD5A 4HWYA 2G8EA 4N79A 1ME4A 2PNSA 1STFE 3U8EA 2VFCA 1K3BB 3K24A 3RVXA 5CHTA 3KSEA 2DCCA 2R9MA 4OEMA 2AUZA 1YK7A 4CZWA 3KWBX 1QOLA 3KWZA 4N8WA 1W4TA 3TNXA 3LXSA 2VFBA 2NQAA 2FT2A 3ZUAA 1GECE 3OF8A 3O0UA 1NQCA 1A6RA 4Q8HA 2FRQA 3CH2X 3B79A 3WXGA 4ZUXU 1KHQA 2G6DA 1AU4A 1PPPA 2AYOA 3QSDA 4P6EA 5CHVA 1KFXL 2NQGA 2AU1A 3BOWA 4W5BA 2XU3A 3H89A 2XU5A 4PI3A 3HD3A 5K16A 1TLOA 2JQGR 3AI8A 8PCHA 1TU6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QJ3 A;  1PE6 A;  1AU3 A;  4XUI A;  3BWK A;  1MHW A;  2E00 A;  5J94 A;  4RY2 A;  3USV A;  3N3G A;  3H8C A;  4YYV A;  3IHP A;  1SNK A;  3HWN A;  3OVX A;  1PCI A;  1AIM A;  3IUT A;  1SP4 B;  5F02 A;  1CS8 A;  2IPP B;  4QBB A;  3C9E A;  4PP1 A;  3CBJ A;  2JQF R;  2G7Y A;  2GFO A;  5EGW A;  1GLO A;  4I07 A;  2OUL A;  3K9M A;  4QRX A;  3N4C A;  9PAP A;  2ATO A;  4X6H A;  1BGO A;  2DJG B;  1XKG A;  1ICF A;  2R9N A;  1NL6 A;  3F5V A;  2HHN A;  3PBH A;  3BPM A;  4CDD B;  1MDW A;  1PPD A;  4QRV A;  2AUX A;  1PXV A;  1CJL A;  3MHH A;  3K8U A;  1DF0 A;  2DC6 A;  2FQ9 A;  1CTE A;  1F2C A;  2E01 A;  2AS8 A;  4YYQ A;  4CDE B;  1CPJ A;  1ZIV A;  1YT7 A;  2CIO A;  2R9O A;  5PAD A;  1HUC B;  1EWO A;  3PDF A;  3O1G A;  1IWD A;  1DEU A;  4YYS A;  1VSN A;  2DC8 A;  1MEG A;  3IMA A;  2PRE A;  4QRG A;  3KKU A;  2F1G A;  3MHS A;  1EWM A;  2NQI A;  4MSX A;  5FPW A;  2XU4 A;  3E1Z B;  3PW3 A;  1U5I A;  2AVW A;  3M99 A;  1TL9 A;  1U9X A;  2YJB A;  1FH0 A;  1GCB A;  3KFQ A;  1PPN A;  4XR7 A;  3KW9 A;  2WBF X;  2B1N A;  1POP A;  2FO5 A;  4OEL A;  4YYU A;  4N4Z A;  1MS6 A;  3H6S A;  2C0Y A;  4PAD A;  2FRA A;  3CBK A;  4CDC B;  1CQD A;  3NHE A;  3WXF A;  3ERV A;  1AYV A;  4FK5 A;  1CV8 A;  3S3Q A;  4BS5 A;  4MZO A;  2AIM A;  1PAD A;  2E03 A;  4AXM A;  1BY8 A;  4WA6 A;  3WXE A;  3P5U A;  4YVA A;  4X6I A;  3LFY A;  2HH5 A;  4BQV A;  2VHF A;  4YV8 A;  2AYN A;  5JA7 A;  2ARY A;  4FJC A;  1QMY A;  3IOQ A;  2F7D A;  2OP3 A;  1ZCM A;  5JH3 A;  1O0E A;  1AU0 A;  2GHU A;  3DF0 A;  3PNR A;  2R9F A;  4YYW A;  3RVW A;  2HXZ A;  3OF9 A;  1S4V A;  3HHI A;  2CB5 A;  4X6J A;  2B1M A;  4YYR A;  3N3K A;  2Y6E A;  2O6X A;  2DCB A;  2FUD A;  2DJF B;  2P86 A;  1F2A A;  3F75 A;  2DZY A;  4G54 A;  2P0R A;  1QDQ A;  2DC7 A;  2DZZ A;  3H7D A;  3IEJ A;  1Y08 A;  1EWP A;  2YJC A;  1ATK A;  2E02 A;  4AXL A;  2FYE A;  1BQI A;  1PIP A;  1YVB A;  1KFU L;  1NB3 A;  2H7J A;  1BP4 A;  2OZ2 A;  2YJ9 A;  4Q8G A;  3S3R A;  2ACT A;  5CVO B;  1F2B A;  1YAL A;  2Y5B A;  1X9Y A;  3P5X A;  1PBH A;  3IV2 A;  3MOR A;  1GMY A;  1THE A;  2VHS A;  3QT4 A;  1PPO A;  4FIP A;  1CB5 A;  2YJ8 A;  3OVZ A;  4CDF B;  1U9W A;  2XU1 A;  4P6G A;  4K7C A;  3CH3 X;  3GCB A;  3I3T A;  1EWL A;  1Q6K A;  4DMY A;  1AYW A;  3BCN A;  4BSQ A;  3BPF A;  2FTD A;  5A24 A;  1F29 A;  3BC3 A;  1ME3 A;  1NPZ A;  4PP2 E;  1U9Q X;  2R6N A;  2P7U A;  7PCK A;  3V6C A;  5CVN B;  4BS6 A;  1AYU A;  1MEM A;  4MZS A;  4BPV A;  2NQD B;  5EF4 A;  4W5C A;  4I04 A;  3D6S A;  3HHA A;  6PAD A;  3KX1 A;  3I06 A;  2DCD A;  1U9V A;  4I05 A;  5CVM A;  2PBH A;  4KLB A;  2DCA A;  2BDZ A;  1Y4H A;  3H8B A;  1VJV A;  2BDL A;  2G8J A;  2IBI A;  3V6E A;  3MTN A;  2YJ2 A;  1EF7 A;  3OIS A;  1CSB B;  1QXP A;  1MIR A;  1NLJ A;  1AEC A;  1KHP A;  1ITO A;  4W4U A;  2R9C A;  4QH6 A;  4DMX A;  1M6D A;  1YK8 A;  1AU2 A;  1KXR A;  3P5W A;  3P5V A;  2DC9 A;  3RVV A;  1NB5 A;  2PAD A;  1CVZ A;  1JQP A;  2HD5 A;  4HWY A;  2G8E A;  4N79 A;  1ME4 A;  2PNS A;  1STF E;  3U8E A;  1K3B B;  3K24 A;  3RVX A;  5CHT A;  3KSE A;  2DCC A;  2R9M A;  4OEM A;  2AUZ A;  1YK7 A;  4CZW A;  3KWB X;  1QOL A;  3KWZ A;  4N8W A;  3TNX A;  3LXS A;  2NQA A;  2FT2 A;  3ZUA A;  1GEC E;  3OF8 A;  3O0U A;  1NQC A;  1A6R A;  4Q8H A;  2FRQ A;  3CH2 X;  3B79 A;  3WXG A;  4ZUX U;  1KHQ A;  2G6D A;  1AU4 A;  1PPP A;  2AYO A;  3QSD A;  4P6E A;  5CHV A;  1KFX L;  2NQG A;  2AU1 A;  3BOW A;  4W5B A;  2XU3 A;  3H89 A;  2XU5 A;  4PI3 A;  3HD3 A;  5K16 A;  1TLO A;  2JQG R;  3AI8 A;  8PCH A;  1TU6 A; 
#chains in the Genus database with same CATH topology
 3QJ3 A;  1PE6 A;  1AU3 A;  4XUI A;  3E9S A;  3BWK A;  3C0R A;  4RF1 A;  1MHW A;  2E00 A;  5J94 A;  4RY2 A;  3USV A;  3N3G A;  3H8C A;  4YYV A;  3IHP A;  1SNK A;  3HWN A;  3OVX A;  1PCI A;  2Z84 A;  1AIM A;  3IUT A;  3W30 A;  1SP4 B;  5F02 A;  4XZX A;  1CS8 A;  2IPP B;  4QBB A;  3C9E A;  4PP1 A;  3CBJ A;  2JQF R;  2G7Y A;  2GFO A;  5EGW A;  1GLO A;  4I07 A;  2OUL A;  3PHX A;  3K9M A;  4QRX A;  3N4C A;  9PAP A;  2ATO A;  4X6H A;  1BGO A;  2DJG B;  1XKG A;  1ICF A;  3PHW A;  2R9N A;  1NL6 A;  4D8B A;  3F5V A;  2HHN A;  3PBH A;  3BPM A;  4CDD B;  1MDW A;  1PPD A;  4QRV A;  2AUX A;  1PXV A;  1CJL A;  3MHH A;  3K8U A;  1DF0 A;  2DC6 A;  2FQ9 A;  1CTE A;  1F2C A;  2E01 A;  2AS8 A;  4YYQ A;  4CDE B;  1CPJ A;  1DKI A;  1ZIV A;  1YT7 A;  4GUA A;  4REZ A;  2CIO A;  2R9O A;  5PAD A;  1HUC B;  3BBA A;  1EWO A;  1YZB A;  3PDF A;  2J7Q A;  3O1G A;  1IWD A;  1DEU A;  4YYS A;  1VSN A;  2DC8 A;  1MEG A;  3IMA A;  2PRE A;  4QRG A;  3KKU A;  2F1G A;  3MHS A;  1EWM A;  2DOS A;  2NQI A;  4MSX A;  5FPW A;  2XU4 A;  3E1Z B;  3PW3 A;  1U5I A;  2AVW A;  3M99 A;  3ZNH A;  1TL9 A;  4BOP A;  1U9X A;  2YJB A;  3TMP A;  3W31 A;  1FH0 A;  1GCB A;  3KFQ A;  1PPN A;  4XR7 A;  2AGA A;  2BTW A;  3KW9 A;  2WBF X;  4RNA A;  2B1N A;  1POP A;  2FO5 A;  4OEL A;  4YYU A;  4N4Z A;  4OW0 A;  3IFU A;  4D8E A;  1MS6 A;  3H6S A;  1UKF A;  2C0Y A;  3OQC A;  4PAD A;  2FRA A;  3CBK A;  4CDC B;  1CQD A;  3NHE A;  3WXF A;  3ERV A;  1AYV A;  4FK5 A;  1CV8 A;  3S3Q A;  4BS5 A;  4MZO A;  2AIM A;  1PAD A;  2E03 A;  4AXM A;  1BY8 A;  4BOZ A;  4WA6 A;  4BOS A;  3WXE A;  3P5U A;  4YVA A;  4X6I A;  3LFY A;  2HH5 A;  4HXD B;  4BQV A;  2VHF A;  4OVZ A;  4YV8 A;  2AYN A;  5JA7 A;  2ARY A;  4FJC A;  1QMY A;  3IOQ A;  2F7D A;  2OP3 A;  3PSE A;  1ZCM A;  5JH3 A;  1O0E A;  1AU0 A;  2GHU A;  3DF0 A;  3PNR A;  2R9F A;  5EZQ A;  4YYW A;  3RVW A;  2HXZ A;  3OF9 A;  2JTC A;  1S4V A;  3HHI A;  2CB5 A;  4X6J A;  2B1M A;  4YYR A;  5EZS A;  3N3K A;  3TRK A;  2Y6E A;  2O6X A;  2DCB A;  2FUD A;  2DJF B;  2P86 A;  1F2A A;  1PVJ A;  3F75 A;  2DZY A;  4G54 A;  2P0R A;  1QDQ A;  2DC7 A;  2DZZ A;  3H7D A;  3IEJ A;  4RF0 A;  1Y08 A;  4MI7 A;  1EWP A;  2YJC A;  1ATK A;  2E02 A;  4AXL A;  2FYE A;  1BQI A;  1PIP A;  1YVB A;  1KFU L;  1NB3 A;  2H7J A;  1BP4 A;  2OZ2 A;  2YJ9 A;  3RNV A;  4Q8G A;  3S3R A;  2ACT A;  5CVO B;  1F2B A;  1YAL A;  4IUM A;  2Y5B A;  1X9Y A;  3P5X A;  2J7Q C;  1PBH A;  3IV2 A;  3MOR A;  1GMY A;  1THE A;  2VHS A;  3QT4 A;  1PPO A;  4FIP A;  1CB5 A;  2YJ8 A;  4MM3 B;  3OVZ A;  4CDF B;  1U9W A;  2XU1 A;  4P6G A;  4K7C A;  3CH3 X;  4P16 A;  3GCB A;  3I3T A;  1EWL A;  1Q6K A;  4DMY A;  1AYW A;  3BCN A;  4A5U A;  4BSQ A;  3BPF A;  4R3D A;  2FTD A;  5A24 A;  1F29 A;  3BC3 A;  4M0W A;  1ME3 A;  1NPZ A;  4WUR A;  4PP2 E;  1U9Q X;  3MTV A;  2R6N A;  2P7U A;  7PCK A;  3V6C A;  2JRI A;  5CVN B;  4BS6 A;  1AYU A;  1MEM A;  4MZS A;  4BPV A;  2BU3 A;  2NQD B;  4BOU A;  5E6J A;  5EF4 A;  4W5C A;  4I04 A;  3D6S A;  3HHA A;  6PAD A;  3KX1 A;  3I06 A;  2DCD A;  3PRP A;  1U9V A;  3MJ5 A;  4I05 A;  5CVM A;  4D8I A;  2PBH A;  4KLB A;  2BTW B;  2DCA A;  2BDZ A;  1Y4H A;  3H8B A;  1VJV A;  3B21 A;  2BDL A;  2G8J A;  2IBI A;  3V6E A;  3MTN A;  2YJ2 A;  1EF7 A;  3OIS A;  5JZE A;  1CSB B;  1QXP A;  1MIR A;  3PT2 A;  1NLJ A;  2FE8 A;  1AEC A;  3MP2 A;  1KHP A;  1ITO A;  2UZJ A;  4W4U A;  3PRM A;  2R9C A;  4QH6 A;  4DMX A;  1M6D A;  1YK8 A;  1AU2 A;  1KXR A;  3P5W A;  3P5V A;  2DC9 A;  3RVV A;  2HWK A;  1NB5 A;  2PAD A;  1CVZ A;  1JQP A;  2HD5 A;  4HWY A;  4IP3 A;  3PHU A;  2G8E A;  4N79 A;  1ME4 A;  2PNS A;  1STF E;  3U8E A;  4BOQ A;  5KO3 A;  1K3B B;  3K24 A;  3RVX A;  5CHT A;  3KSE A;  2DCC A;  2R9M A;  4OEM A;  2AUZ A;  1YK7 A;  4OVZ B;  4CZW A;  3KWB X;  1QOL A;  3KWZ A;  4N8W A;  3BY4 A;  4ZTB A;  3TNX A;  3LXS A;  2NQA A;  2FT2 A;  3ZUA A;  1GEC E;  3OF8 A;  3O0U A;  1NQC A;  1A6R A;  4Q8H A;  2FRQ A;  3CH2 X;  3B79 A;  3WXG A;  4ZUX U;  1KHQ A;  3O65 A;  2G6D A;  1AU4 A;  1PPP A;  2AYO A;  3QSD A;  4P6E A;  5CHV A;  1KFX L;  4RKX A;  3BB7 A;  2NQG A;  2AU1 A;  3BOW A;  4W5B A;  2XU3 A;  3H89 A;  2XU5 A;  4PI3 A;  3HD3 A;  4PT5 A;  5K16 A;  1TLO A;  2JQG R;  3AI8 A;  8PCH A;  1TU6 A; 
#chains in the Genus database with same CATH homology
 3QJ3 A;  1PE6 A;  1AU3 A;  4XUI A;  3BWK A;  1MHW A;  3D9W A;  2E00 A;  5J94 A;  4RY2 A;  3USV A;  3N3G A;  3H8C A;  4YYV A;  3IHP A;  1SNK A;  3HWN A;  3OVX A;  1PCI A;  1AIM A;  3IUT A;  1SP4 B;  1E2T A;  5F02 A;  1CS8 A;  2IPP B;  4QBB A;  3C9E A;  4PP1 A;  3CBJ A;  2JQF R;  2G7Y A;  2GFO A;  5EGW A;  1GLO A;  4I07 A;  2OUL A;  3K9M A;  2BSZ A;  4QRX A;  3N4C A;  9PAP A;  2ATO A;  4X6H A;  1BGO A;  2DJG B;  1XKG A;  1ICF A;  2R9N A;  1NL6 A;  3F5V A;  2HHN A;  3PBH A;  3BPM A;  4CDD B;  1MDW A;  1PPD A;  4QRV A;  2AUX A;  1PXV A;  1CJL A;  3MHH A;  3K8U A;  1DF0 A;  2DC6 A;  2FQ9 A;  1CTE A;  1F2C A;  2E01 A;  2AS8 A;  4YYQ A;  4CDE B;  1CPJ A;  1ZIV A;  1YT7 A;  2CIO A;  2R9O A;  5PAD A;  1HUC B;  1EWO A;  3PDF A;  3O1G A;  1IWD A;  1DEU A;  4YYS A;  1VSN A;  2DC8 A;  1MEG A;  3IMA A;  2PRE A;  4QRG A;  3KKU A;  2F1G A;  3MHS A;  4NV7 A;  1EWM A;  2NQI A;  4MSX A;  5FPW A;  2XU4 A;  3E1Z B;  3PW3 A;  1U5I A;  2AVW A;  3M99 A;  1TL9 A;  1U9X A;  2YJB A;  1FH0 A;  1GCB A;  3KFQ A;  1PPN A;  4XR7 A;  3KW9 A;  2WBF X;  2B1N A;  1POP A;  2FO5 A;  4OEL A;  4YYU A;  4N4Z A;  1MS6 A;  3H6S A;  2C0Y A;  1W6F A;  4PAD A;  2FRA A;  3CBK A;  4CDC B;  1CQD A;  3NHE A;  3WXF A;  3ERV A;  1AYV A;  4FK5 A;  1CV8 A;  3S3Q A;  4BS5 A;  4MZO A;  2AIM A;  1PAD A;  2E03 A;  4AXM A;  1BY8 A;  4WA6 A;  3WXE A;  3P5U A;  4YVA A;  4X6I A;  3LFY A;  2HH5 A;  4BQV A;  4GUZ A;  2VHF A;  4YV8 A;  2AYN A;  5JA7 A;  2ARY A;  4FJC A;  1QMY A;  3IOQ A;  2F7D A;  2OP3 A;  1ZCM A;  5JH3 A;  1O0E A;  1W5R A;  1AU0 A;  4B55 A;  2GHU A;  3DF0 A;  3PNR A;  2R9F A;  4YYW A;  3RVW A;  2HXZ A;  3OF9 A;  1S4V A;  3HHI A;  2CB5 A;  4X6J A;  2B1M A;  4YYR A;  3LTW A;  3N3K A;  2Y6E A;  2O6X A;  2DCB A;  2FUD A;  2DJF B;  2P86 A;  1F2A A;  3F75 A;  2DZY A;  4G54 A;  2P0R A;  1QDQ A;  2DC7 A;  2DZZ A;  3H7D A;  3IEJ A;  1Y08 A;  1EWP A;  2YJC A;  1ATK A;  2E02 A;  4AXL A;  2FYE A;  1BQI A;  1PIP A;  1YVB A;  1KFU L;  1NB3 A;  2H7J A;  1BP4 A;  2OZ2 A;  2YJ9 A;  4Q8G A;  3S3R A;  2ACT A;  5CVO B;  1F2B A;  1YAL A;  2Y5B A;  1X9Y A;  3P5X A;  1PBH A;  3IV2 A;  3MOR A;  1GMY A;  1THE A;  2VHS A;  3QT4 A;  1PPO A;  4FIP A;  4BGF A;  1CB5 A;  2YJ8 A;  3OVZ A;  4CDF B;  1U9W A;  2XU1 A;  4P6G A;  4K7C A;  3CH3 X;  3GCB A;  3I3T A;  1EWL A;  1Q6K A;  4DMY A;  1AYW A;  3BCN A;  4BSQ A;  3BPF A;  2FTD A;  5A24 A;  1F29 A;  3BC3 A;  1ME3 A;  1NPZ A;  4PP2 E;  1U9Q X;  2R6N A;  2P7U A;  7PCK A;  3V6C A;  5CVN B;  4BS6 A;  1AYU A;  1MEM A;  4MZS A;  4BPV A;  2NQD B;  5EF4 A;  4W5C A;  4I04 A;  3D6S A;  3HHA A;  6PAD A;  3KX1 A;  3I06 A;  2DCD A;  1U9V A;  4I05 A;  5CVM A;  4C5P A;  2PBH A;  4KLB A;  4NV8 A;  2DCA A;  2BDZ A;  1Y4H A;  3H8B A;  1VJV A;  2BDL A;  2G8J A;  2IBI A;  3V6E A;  3MTN A;  2YJ2 A;  1EF7 A;  3OIS A;  1CSB B;  1QXP A;  1MIR A;  1NLJ A;  1AEC A;  1KHP A;  1ITO A;  4W4U A;  2R9C A;  4QH6 A;  4DMX A;  1M6D A;  1YK8 A;  1AU2 A;  1KXR A;  3P5W A;  3P5V A;  2DC9 A;  3RVV A;  1GX3 A;  1NB5 A;  2PAD A;  1CVZ A;  1JQP A;  2HD5 A;  4HWY A;  2G8E A;  4N79 A;  1ME4 A;  2PNS A;  1STF E;  3U8E A;  2VFC A;  1K3B B;  3K24 A;  3RVX A;  5CHT A;  3KSE A;  2DCC A;  2R9M A;  4OEM A;  2AUZ A;  1YK7 A;  4CZW A;  3KWB X;  1QOL A;  3KWZ A;  4N8W A;  1W4T A;  3TNX A;  3LXS A;  2VFB A;  2NQA A;  2FT2 A;  3ZUA A;  1GEC E;  3OF8 A;  3O0U A;  1NQC A;  1A6R A;  4Q8H A;  2FRQ A;  3CH2 X;  3B79 A;  3WXG A;  4ZUX U;  1KHQ A;  2G6D A;  1AU4 A;  1PPP A;  2AYO A;  3QSD A;  4P6E A;  5CHV A;  1KFX L;  2NQG A;  2AU1 A;  3BOW A;  4W5B A;  2XU3 A;  3H89 A;  2XU5 A;  4PI3 A;  3HD3 A;  5K16 A;  1TLO A;  2JQG R;  3AI8 A;  8PCH A;  1TU6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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