2G8EA

Calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
326
structure length
326
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 100
structure length 326
sequence length 326
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8eA02
2B1NA 2GFOA 2R9FA 1YVBA 1NQCA 4MZSA 2FRQA 4BS5A 2AU1A 4FIPA 4CDDB 2F1GA 1BGOA 5F02A 4CDEB 4BQVA 5CVMA 3LFYA 2H7JA 2O6XA 3QT4A 2HXZA 1DEUA 3PNRA 4G54A 3V6EA 4QBBA 4QRVA 3N4CA 2FRAA 3CH3X 1EF7A 4YYQA 2ARYA 1U9VA 3RVWA 3CH2X 1F29A 1KFUL 2B1MA 1TL9A 3N3KA 2OZ2A 2DC7A 2NQAA 1CVZA 5A24A 3RVXA 3K24A 2VHSA 3O1GA 2PADA 1CV8A 5J94A 3S3QA 2G7YA 1GLOA 1O0EA 2YJBA 2FQ9A 3QJ3A 2AIMA 2R6NA 4I04A 3KWZA 1ATKA 4ZUXU 3ZUAA 1MS6A 4RY2A 1ZCMA 2WBFX 8PCHA 3B79A 1MHWA 1GECE 1ME3A 2FT2A 1CJLA 2DJFB 4XUIA 4YYUA 1AECA 1MDWA 1ME4A 2XU4A 4BSQA 3MHHA 3KW9A 1SNKA 3M99A 4PP2E 1S4VA 1MIRA 3NHEA 5FPWA 1XKGA 1YK8A 1NL6A 3CBKA 3OF8A 1M6DA 4YYWA 2AYNA 4CZWA 4YVAA 1VJVA 3BCNA 3H8BA 2F7DA 1F2AA 1AU3A 1AIMA 2IBIA 1IWDA 2G6DA 4N8WA 3BC3A 6PADA 1AYVA 3H8CA 4DMXA 3IOQA 1QMYA 1ZIVA 2DCAA 1NLJA 3F75A 2DCDA 4BS6A 2BDZA 3MHSA 3HD3A 1DF0A 3HWNA 3N3GA 1CTEA 1U9XA 3P5UA 4N79A 1NPZA 3OVZA 2FUDA 3F5VA 2CIOA 7PCKA 3H89A 4OELA 1NB5A 2IPPB 3RVVA 2E02A 2Y6EA 1THEA 4FK5A 2YJ8A 2HH5A 4QRGA 4X6HA 3QSDA 1PCIA 5CVOB 1KHQA 2NQDB 1BP4A 5EF4A 2HD5A 1FH0A 2OP3A 2YJ2A 1Y08A 3IHPA 3CBJA 4Q8HA 1AU2A 1CPJA 3C9EA 3MORA 1U9WA 1KXRA 1EWOA 2FO5A 3MTNA 3KKUA 1EWMA 1Q6KA 1QDQA 2ATOA 4P6EA 2AYOA 2DJGB 4X6JA 3BPMA 4MZOA 1AYWA 5EGWA 4XR7A 1CS8A 1PPDA 2PREA 1F2BA 3ERVA 2YJ9A 1TU6A 3I06A 3U8EA 1YK7A 3HHAA 4CDFB 2PBHA 3E1ZB 4W5CA 2DZYA 4HWYA 4X6IA 1CQDA 4FJCA 2AUXA 3PW3A 1GMYA 4OEMA 1STFE 3IUTA 3H7DA 5PADA 3DF0A 1GCBA 4PP1A 1PE6A 2ACTA 4KLBA 3S3RA 2DCCA 3AI8A 1VSNA 1PIPA 4K7CA 2DC6A 1K3BB 3D6SA 3KSEA 3P5VA 2FYEA 2BDLA 1POPA 1QXPA 3BPFA 4AXLA 1Y4HA 2OULA 4BPVA 3K9MA 2NQIA 2R9MA 1HUCB 1X9YA 1PPPA 4P6GA 3I3TA 4QH6A 2G8EA 3OVXA 1PBHA 5JA7A 4N4ZA 4YYRA 4PI3A 2Y5BA 3KX1A 3PDFA 4W5BA 2DC9A 2XU3A 4MSXA 3WXEA 2DZZA 2P7UA 3PBHA 4AXMA 3P5XA 1YT7A 1BQIA 5K16A 4CDCB 1CB5A 1AU0A 2AVWA 2XU5A 1JQPA 1EWLA 3H6SA 5CHVA 2HHNA 4DMYA 2R9NA 1CSBB 3IEJA 2NQGA 3O0UA 2DC8A 4W4UA 3GCBA 1EWPA 3TNXA 4I07A 2E03A 2G8JA 3V6CA 1U9QX 2CB5A 2DCBA 3LXSA 3KWBX 9PAPA 1ITOA 1QOLA 1YALA 2R9CA 2YJCA 1U5IA 2AS8A 3BOWA 3WXGA 5JH3A 2AUZA 1BY8A 2R9OA 1NB3A 1MEGA 1A6RA 4YYSA 1KFXL 2JQGR 1AU4A 3KFQA 1PPNA 1SP4B 2FTDA 4WA6A 2PNSA 3OISA 1ICFA 1AYUA 1PADA 3IMAA 1MEMA 3USVA 1PPOA 4QRXA 2E00A 5CHTA 5CVNB 3HHIA 3WXFA 3P5WA 4Q8GA 4YYVA 1KHPA 1PXVA 2XU1A 3IV2A 2JQFR 1TLOA 2VHFA 3K8UA 2P86A 4YV8A 3OF9A 4I05A 4PADA 2P0RA 3BWKA 1F2CA 2GHUA 2E01A 2C0YA
chains in the Genus database with same CATH superfamily
2B1NA 2GFOA 2R9FA 1YVBA 1NQCA 4MZSA 2FRQA 4BS5A 2AU1A 3PSEA 4FIPA 4CDDB 2F1GA 1BGOA 5F02A 4CDEB 4BQVA 3IFUA 5CVMA 3LFYA 2H7JA 2BU3A 2O6XA 3QT4A 2HXZA 1DEUA 2FE8A 2BTWA 3PNRA 4G54A 3V6EA 4QBBA 4QRVA 5KO3A 3N4CA 2FRAA 3CH3X 1EF7A 4YYQA 2ARYA 1U9VA 3E9SA 3RVWA 3CH2X 1F29A 1KFUL 2B1MA 1TL9A 3N3KA 4ZTBA 2OZ2A 2DC7A 2NQAA 1CVZA 5A24A 3RVXA 3K24A 2VHSA 3O1GA 2PADA 1CV8A 5J94A 3S3QA 2G7YA 1GLOA 1O0EA 2YJBA 2JRIA 2FQ9A 3QJ3A 2AIMA 2R6NA 4I04A 3KWZA 1ATKA 4ZUXU 1DKIA 3ZUAA 1MS6A 4RY2A 4P16A 1ZCMA 2WBFX 8PCHA 3B79A 1MHWA 1GECE 1ME3A 2FT2A 1CJLA 2DJFB 4XUIA 4YYUA 1AECA 1MDWA 1ME4A 2XU4A 4BSQA 3MHHA 3KW9A 1SNKA 3M99A 4PP2E 1S4VA 1MIRA 3MTVA 3NHEA 3MJ5A 3MP2A 5FPWA 1XKGA 1YK8A 1NL6A 3CBKA 3OF8A 1M6DA 4BOPA 4YYWA 2AYNA 4CZWA 4YVAA 1VJVA 3BCNA 4OVZA 3H8BA 2F7DA 1F2AA 3RNVA 1AU3A 3PHUA 1AIMA 2IBIA 1IWDA 2G6DA 4N8WA 3ZNHA 3BC3A 6PADA 1AYVA 4RKXA 3B21A 3H8CA 4DMXA 3IOQA 1QMYA 1ZIVA 2DCAA 1NLJA 3F75A 2DCDA 3C0RA 4BS6A 2BDZA 3MHSA 3HD3A 1DF0A 3TMPA 3HWNA 3N3GA 1CTEA 1U9XA 3P5UA 4N79A 1NPZA 3OVZA 2FUDA 3F5VA 3PHXA 2CIOA 7PCKA 3H89A 4R3DA 4BOQA 4OELA 1NB5A 2IPPB 3RVVA 2E02A 2Y6EA 1THEA 4FK5A 2YJ8A 2HH5A 4QRGA 4X6HA 3QSDA 4WURA 1PCIA 5CVOB 1KHQA 5EZSA 2J7QC 2NQDB 1BP4A 5EF4A 2HD5A 3W31A 1FH0A 2OP3A 2YJ2A 1Y08A 3IHPA 3CBJA 4Q8HA 1AU2A 1CPJA 3C9EA 3MORA 4IP3A 1U9WA 1KXRA 1EWOA 2FO5A 3MTNA 3KKUA 1EWMA 1Q6KA 1QDQA 2ATOA 4P6EA 2AYOA 2DJGB 4X6JA 3BPMA 4MZOA 1AYWA 5EGWA 4XR7A 1CS8A 1PPDA 2PREA 1F2BA 3ERVA 2YJ9A 4M0WA 1TU6A 3I06A 2AGAA 3U8EA 1YK7A 3HHAA 4CDFB 2HWKA 4OW0A 4XZXA 2PBHA 3E1ZB 4W5CA 2DZYA 4HWYA 4X6IA 1CQDA 4FJCA 2AUXA 3PW3A 1GMYA 4OEMA 4PT5A 1STFE 3IUTA 3H7DA 3PRMA 5PADA 3DF0A 1GCBA 2UZJA 1YZBA 4PP1A 1PE6A 2ACTA 4KLBA 3S3RA 2DCCA 4MM3B 3AI8A 1VSNA 1PIPA 4K7CA 5E6JA 2DC6A 1K3BB 4D8IA 3D6SA 3KSEA 3P5VA 2FYEA 2BDLA 1POPA 1QXPA 3BPFA 2JTCA 4AXLA 1Y4HA 2OULA 4BPVA 3K9MA 2NQIA 2R9MA 4A5UA 1HUCB 1X9YA 1PPPA 4P6GA 3I3TA 4QH6A 2G8EA 3OVXA 1PBHA 5JA7A 4GUAA 4N4ZA 4YYRA 4PI3A 2Y5BA 3KX1A 3PDFA 4W5BA 2DC9A 2XU3A 1UKFA 4MSXA 3PT2A 3WXEA 2DZZA 3PRPA 2P7UA 3PBHA 4AXMA 3P5XA 1YT7A 1BQIA 5EZQA 5K16A 4CDCB 4MI7A 1CB5A 1AU0A 2AVWA 2XU5A 4D8EA 1JQPA 1EWLA 3H6SA 5CHVA 2HHNA 4DMYA 2R9NA 1CSBB 3IEJA 2NQGA 3O0UA 2DC8A 4W4UA 3GCBA 3OQCA 3BY4A 2BTWB 1EWPA 3TNXA 5JZEA 4I07A 2DOSA 2E03A 3O65A 2G8JA 2Z84A 3V6CA 4IUMA 4BOZA 4BOUA 1U9QX 2CB5A 2DCBA 3LXSA 3PHWA 3KWBX 9PAPA 4RF0A 1ITOA 1QOLA 1YALA 2R9CA 2YJCA 3BBAA 1U5IA 2AS8A 3BOWA 3WXGA 3BB7A 4BOSA 5JH3A 2AUZA 1BY8A 2R9OA 1NB3A 4RF1A 1MEGA 1A6RA 4YYSA 1KFXL 2JQGR 4RNAA 1AU4A 3KFQA 1PPNA 1SP4B 2FTDA 4WA6A 2PNSA 3OISA 1ICFA 1AYUA 1PADA 3IMAA 1MEMA 4HXDB 3W30A 3USVA 1PPOA 4QRXA 2E00A 5CHTA 1PVJA 5CVNB 3HHIA 3WXFA 3P5WA 4Q8GA 4YYVA 2J7QA 4REZA 1KHPA 1PXVA 2XU1A 3IV2A 2JQFR 1TLOA 2VHFA 3K8UA 4D8BA 2P86A 4YV8A 3OF9A 4OVZB 4I05A 4PADA 3TRKA 2P0RA 3BWKA 1F2CA 2GHUA 2E01A 2C0YA
chains in the Genus database with same CATH topology
2B1NA 2GFOA 2R9FA 1YVBA 1NQCA 4MZSA 2FRQA 4BS5A 2AU1A 4FIPA 4CDDB 2F1GA 1BGOA 5F02A 4CDEB 4BQVA 5CVMA 3LFYA 2H7JA 2O6XA 3QT4A 2HXZA 1DEUA 3PNRA 4G54A 3V6EA 4QBBA 1W4TA 4QRVA 3N4CA 2FRAA 3CH3X 4GUZA 1EF7A 4YYQA 2ARYA 1U9VA 3RVWA 3CH2X 1F29A 1KFUL 2B1MA 1TL9A 3N3KA 2OZ2A 2DC7A 2NQAA 1CVZA 5A24A 3RVXA 3K24A 2VHSA 3O1GA 2PADA 1CV8A 2VFCA 5J94A 3S3QA 2G7YA 1GLOA 1O0EA 2YJBA 2FQ9A 3QJ3A 2AIMA 2R6NA 4I04A 3KWZA 1ATKA 4ZUXU 3ZUAA 1MS6A 4RY2A 1ZCMA 2WBFX 8PCHA 3B79A 1MHWA 1GECE 1ME3A 2FT2A 1CJLA 2DJFB 4XUIA 4YYUA 1AECA 1MDWA 1ME4A 2XU4A 4C5PA 4BSQA 3MHHA 3KW9A 1SNKA 3M99A 4PP2E 1S4VA 1MIRA 3NHEA 5FPWA 1XKGA 1YK8A 1NL6A 3CBKA 3OF8A 1M6DA 4YYWA 2AYNA 4CZWA 4YVAA 1VJVA 3BCNA 3H8BA 2F7DA 1F2AA 1AU3A 3LTWA 1AIMA 2IBIA 1IWDA 2G6DA 4N8WA 3BC3A 6PADA 1AYVA 3H8CA 4DMXA 3IOQA 1QMYA 4BGFA 1ZIVA 2DCAA 1NLJA 3F75A 2DCDA 4BS6A 2BDZA 3MHSA 3HD3A 1DF0A 1W5RA 3HWNA 3N3GA 1CTEA 1U9XA 3P5UA 4N79A 1NPZA 3OVZA 2FUDA 3F5VA 2CIOA 7PCKA 4NV8A 3H89A 4OELA 1NB5A 2IPPB 3RVVA 2E02A 2Y6EA 1THEA 4FK5A 2YJ8A 2HH5A 4QRGA 4X6HA 3QSDA 1PCIA 5CVOB 1KHQA 2NQDB 1BP4A 5EF4A 2HD5A 1FH0A 2OP3A 2YJ2A 1Y08A 3IHPA 3CBJA 4Q8HA 1AU2A 1CPJA 3C9EA 3MORA 1U9WA 1KXRA 1EWOA 2FO5A 3MTNA 3KKUA 1EWMA 1Q6KA 1QDQA 2ATOA 4P6EA 2AYOA 2DJGB 4X6JA 3BPMA 4MZOA 1AYWA 5EGWA 4XR7A 1CS8A 1PPDA 2PREA 1F2BA 3ERVA 2YJ9A 1TU6A 3I06A 3U8EA 1YK7A 3HHAA 4CDFB 2PBHA 3E1ZB 4W5CA 2DZYA 4HWYA 4X6IA 1CQDA 4FJCA 2AUXA 3PW3A 1GMYA 4OEMA 1STFE 3IUTA 3H7DA 1E2TA 5PADA 3DF0A 1GCBA 4PP1A 1PE6A 2ACTA 4KLBA 3S3RA 2DCCA 3AI8A 1VSNA 4B55A 1PIPA 4K7CA 2DC6A 1K3BB 3D6SA 3KSEA 3P5VA 2FYEA 2BDLA 1POPA 1QXPA 4NV7A 3BPFA 4AXLA 1Y4HA 2OULA 4BPVA 3K9MA 2NQIA 2R9MA 1HUCB 1X9YA 1PPPA 4P6GA 1W6FA 3I3TA 4QH6A 2G8EA 3OVXA 1PBHA 5JA7A 4N4ZA 4YYRA 4PI3A 2Y5BA 3KX1A 3PDFA 4W5BA 2DC9A 2XU3A 4MSXA 3WXEA 2DZZA 2P7UA 3PBHA 4AXMA 3P5XA 1YT7A 1BQIA 5K16A 4CDCB 1CB5A 1AU0A 2AVWA 2XU5A 1JQPA 1EWLA 3H6SA 5CHVA 2HHNA 4DMYA 2R9NA 1CSBB 3IEJA 2NQGA 3O0UA 2DC8A 4W4UA 3GCBA 1EWPA 3TNXA 4I07A 2E03A 2G8JA 3V6CA 1U9QX 2CB5A 2DCBA 3LXSA 3KWBX 9PAPA 1ITOA 1QOLA 1YALA 2R9CA 2YJCA 1U5IA 2VFBA 2AS8A 3BOWA 3WXGA 5JH3A 2AUZA 1BY8A 2R9OA 1NB3A 1MEGA 1A6RA 4YYSA 1KFXL 2JQGR 1AU4A 3KFQA 1PPNA 1SP4B 2FTDA 1GX3A 4WA6A 2PNSA 3OISA 1ICFA 1AYUA 1PADA 3IMAA 1MEMA 3USVA 1PPOA 4QRXA 2E00A 5CHTA 2BSZA 5CVNB 3HHIA 3WXFA 3P5WA 4Q8GA 4YYVA 1KHPA 1PXVA 2XU1A 3IV2A 2JQFR 1TLOA 2VHFA 3D9WA 3K8UA 2P86A 4YV8A 3OF9A 4I05A 4PADA 2P0RA 3BWKA 1F2CA 2GHUA 2E01A 2C0YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B1N A;  2GFO A;  2R9F A;  1YVB A;  1NQC A;  4MZS A;  2FRQ A;  4BS5 A;  2AU1 A;  4FIP A;  4CDD B;  2F1G A;  1BGO A;  5F02 A;  4CDE B;  4BQV A;  5CVM A;  3LFY A;  2H7J A;  2O6X A;  3QT4 A;  2HXZ A;  1DEU A;  3PNR A;  4G54 A;  3V6E A;  4QBB A;  4QRV A;  3N4C A;  2FRA A;  3CH3 X;  1EF7 A;  4YYQ A;  2ARY A;  1U9V A;  3RVW A;  3CH2 X;  1F29 A;  1KFU L;  2B1M A;  1TL9 A;  3N3K A;  2OZ2 A;  2DC7 A;  2NQA A;  1CVZ A;  5A24 A;  3RVX A;  3K24 A;  2VHS A;  3O1G A;  2PAD A;  1CV8 A;  5J94 A;  3S3Q A;  2G7Y A;  1GLO A;  1O0E A;  2YJB A;  2FQ9 A;  3QJ3 A;  2AIM A;  2R6N A;  4I04 A;  3KWZ A;  1ATK A;  4ZUX U;  3ZUA A;  1MS6 A;  4RY2 A;  1ZCM A;  2WBF X;  8PCH A;  3B79 A;  1MHW A;  1GEC E;  1ME3 A;  2FT2 A;  1CJL A;  2DJF B;  4XUI A;  4YYU A;  1AEC A;  1MDW A;  1ME4 A;  2XU4 A;  4BSQ A;  3MHH A;  3KW9 A;  1SNK A;  3M99 A;  4PP2 E;  1S4V A;  1MIR A;  3NHE A;  5FPW A;  1XKG A;  1YK8 A;  1NL6 A;  3CBK A;  3OF8 A;  1M6D A;  4YYW A;  2AYN A;  4CZW A;  4YVA A;  1VJV A;  3BCN A;  3H8B A;  2F7D A;  1F2A A;  1AU3 A;  1AIM A;  2IBI A;  1IWD A;  2G6D A;  4N8W A;  3BC3 A;  6PAD A;  1AYV A;  3H8C A;  4DMX A;  3IOQ A;  1QMY A;  1ZIV A;  2DCA A;  1NLJ A;  3F75 A;  2DCD A;  4BS6 A;  2BDZ A;  3MHS A;  3HD3 A;  1DF0 A;  3HWN A;  3N3G A;  1CTE A;  1U9X A;  3P5U A;  4N79 A;  1NPZ A;  3OVZ A;  2FUD A;  3F5V A;  2CIO A;  7PCK A;  3H89 A;  4OEL A;  1NB5 A;  2IPP B;  3RVV A;  2E02 A;  2Y6E A;  1THE A;  4FK5 A;  2YJ8 A;  2HH5 A;  4QRG A;  4X6H A;  3QSD A;  1PCI A;  5CVO B;  1KHQ A;  2NQD B;  1BP4 A;  5EF4 A;  2HD5 A;  1FH0 A;  2OP3 A;  2YJ2 A;  1Y08 A;  3IHP A;  3CBJ A;  4Q8H A;  1AU2 A;  1CPJ A;  3C9E A;  3MOR A;  1U9W A;  1KXR A;  1EWO A;  2FO5 A;  3MTN A;  3KKU A;  1EWM A;  1Q6K A;  1QDQ A;  2ATO A;  4P6E A;  2AYO A;  2DJG B;  4X6J A;  3BPM A;  4MZO A;  1AYW A;  5EGW A;  4XR7 A;  1CS8 A;  1PPD A;  2PRE A;  1F2B A;  3ERV A;  2YJ9 A;  1TU6 A;  3I06 A;  3U8E A;  1YK7 A;  3HHA A;  4CDF B;  2PBH A;  3E1Z B;  4W5C A;  2DZY A;  4HWY A;  4X6I A;  1CQD A;  4FJC A;  2AUX A;  3PW3 A;  1GMY A;  4OEM A;  1STF E;  3IUT A;  3H7D A;  5PAD A;  3DF0 A;  1GCB A;  4PP1 A;  1PE6 A;  2ACT A;  4KLB A;  3S3R A;  2DCC A;  3AI8 A;  1VSN A;  1PIP A;  4K7C A;  2DC6 A;  1K3B B;  3D6S A;  3KSE A;  3P5V A;  2FYE A;  2BDL A;  1POP A;  1QXP A;  3BPF A;  4AXL A;  1Y4H A;  2OUL A;  4BPV A;  3K9M A;  2NQI A;  2R9M A;  1HUC B;  1X9Y A;  1PPP A;  4P6G A;  3I3T A;  4QH6 A;  2G8E A;  3OVX A;  1PBH A;  5JA7 A;  4N4Z A;  4YYR A;  4PI3 A;  2Y5B A;  3KX1 A;  3PDF A;  4W5B A;  2DC9 A;  2XU3 A;  4MSX A;  3WXE A;  2DZZ A;  2P7U A;  3PBH A;  4AXM A;  3P5X A;  1YT7 A;  1BQI A;  5K16 A;  4CDC B;  1CB5 A;  1AU0 A;  2AVW A;  2XU5 A;  1JQP A;  1EWL A;  3H6S A;  5CHV A;  2HHN A;  4DMY A;  2R9N A;  1CSB B;  3IEJ A;  2NQG A;  3O0U A;  2DC8 A;  4W4U A;  3GCB A;  1EWP A;  3TNX A;  4I07 A;  2E03 A;  2G8J A;  3V6C A;  1U9Q X;  2CB5 A;  2DCB A;  3LXS A;  3KWB X;  9PAP A;  1ITO A;  1QOL A;  1YAL A;  2R9C A;  2YJC A;  1U5I A;  2AS8 A;  3BOW A;  3WXG A;  5JH3 A;  2AUZ A;  1BY8 A;  2R9O A;  1NB3 A;  1MEG A;  1A6R A;  4YYS A;  1KFX L;  2JQG R;  1AU4 A;  3KFQ A;  1PPN A;  1SP4 B;  2FTD A;  4WA6 A;  2PNS A;  3OIS A;  1ICF A;  1AYU A;  1PAD A;  3IMA A;  1MEM A;  3USV A;  1PPO A;  4QRX A;  2E00 A;  5CHT A;  5CVN B;  3HHI A;  3WXF A;  3P5W A;  4Q8G A;  4YYV A;  1KHP A;  1PXV A;  2XU1 A;  3IV2 A;  2JQF R;  1TLO A;  2VHF A;  3K8U A;  2P86 A;  4YV8 A;  3OF9 A;  4I05 A;  4PAD A;  2P0R A;  3BWK A;  1F2C A;  2GHU A;  2E01 A;  2C0Y A; 
#chains in the Genus database with same CATH topology
 2B1N A;  2GFO A;  2R9F A;  1YVB A;  1NQC A;  4MZS A;  2FRQ A;  4BS5 A;  2AU1 A;  3PSE A;  4FIP A;  4CDD B;  2F1G A;  1BGO A;  5F02 A;  4CDE B;  4BQV A;  3IFU A;  5CVM A;  3LFY A;  2H7J A;  2BU3 A;  2O6X A;  3QT4 A;  2HXZ A;  1DEU A;  2FE8 A;  2BTW A;  3PNR A;  4G54 A;  3V6E A;  4QBB A;  4QRV A;  5KO3 A;  3N4C A;  2FRA A;  3CH3 X;  1EF7 A;  4YYQ A;  2ARY A;  1U9V A;  3E9S A;  3RVW A;  3CH2 X;  1F29 A;  1KFU L;  2B1M A;  1TL9 A;  3N3K A;  4ZTB A;  2OZ2 A;  2DC7 A;  2NQA A;  1CVZ A;  5A24 A;  3RVX A;  3K24 A;  2VHS A;  3O1G A;  2PAD A;  1CV8 A;  5J94 A;  3S3Q A;  2G7Y A;  1GLO A;  1O0E A;  2YJB A;  2JRI A;  2FQ9 A;  3QJ3 A;  2AIM A;  2R6N A;  4I04 A;  3KWZ A;  1ATK A;  4ZUX U;  1DKI A;  3ZUA A;  1MS6 A;  4RY2 A;  4P16 A;  1ZCM A;  2WBF X;  8PCH A;  3B79 A;  1MHW A;  1GEC E;  1ME3 A;  2FT2 A;  1CJL A;  2DJF B;  4XUI A;  4YYU A;  1AEC A;  1MDW A;  1ME4 A;  2XU4 A;  4BSQ A;  3MHH A;  3KW9 A;  1SNK A;  3M99 A;  4PP2 E;  1S4V A;  1MIR A;  3MTV A;  3NHE A;  3MJ5 A;  3MP2 A;  5FPW A;  1XKG A;  1YK8 A;  1NL6 A;  3CBK A;  3OF8 A;  1M6D A;  4BOP A;  4YYW A;  2AYN A;  4CZW A;  4YVA A;  1VJV A;  3BCN A;  4OVZ A;  3H8B A;  2F7D A;  1F2A A;  3RNV A;  1AU3 A;  3PHU A;  1AIM A;  2IBI A;  1IWD A;  2G6D A;  4N8W A;  3ZNH A;  3BC3 A;  6PAD A;  1AYV A;  4RKX A;  3B21 A;  3H8C A;  4DMX A;  3IOQ A;  1QMY A;  1ZIV A;  2DCA A;  1NLJ A;  3F75 A;  2DCD A;  3C0R A;  4BS6 A;  2BDZ A;  3MHS A;  3HD3 A;  1DF0 A;  3TMP A;  3HWN A;  3N3G A;  1CTE A;  1U9X A;  3P5U A;  4N79 A;  1NPZ A;  3OVZ A;  2FUD A;  3F5V A;  3PHX A;  2CIO A;  7PCK A;  3H89 A;  4R3D A;  4BOQ A;  4OEL A;  1NB5 A;  2IPP B;  3RVV A;  2E02 A;  2Y6E A;  1THE A;  4FK5 A;  2YJ8 A;  2HH5 A;  4QRG A;  4X6H A;  3QSD A;  4WUR A;  1PCI A;  5CVO B;  1KHQ A;  5EZS A;  2J7Q C;  2NQD B;  1BP4 A;  5EF4 A;  2HD5 A;  3W31 A;  1FH0 A;  2OP3 A;  2YJ2 A;  1Y08 A;  3IHP A;  3CBJ A;  4Q8H A;  1AU2 A;  1CPJ A;  3C9E A;  3MOR A;  4IP3 A;  1U9W A;  1KXR A;  1EWO A;  2FO5 A;  3MTN A;  3KKU A;  1EWM A;  1Q6K A;  1QDQ A;  2ATO A;  4P6E A;  2AYO A;  2DJG B;  4X6J A;  3BPM A;  4MZO A;  1AYW A;  5EGW A;  4XR7 A;  1CS8 A;  1PPD A;  2PRE A;  1F2B A;  3ERV A;  2YJ9 A;  4M0W A;  1TU6 A;  3I06 A;  2AGA A;  3U8E A;  1YK7 A;  3HHA A;  4CDF B;  2HWK A;  4OW0 A;  4XZX A;  2PBH A;  3E1Z B;  4W5C A;  2DZY A;  4HWY A;  4X6I A;  1CQD A;  4FJC A;  2AUX A;  3PW3 A;  1GMY A;  4OEM A;  4PT5 A;  1STF E;  3IUT A;  3H7D A;  3PRM A;  5PAD A;  3DF0 A;  1GCB A;  2UZJ A;  1YZB A;  4PP1 A;  1PE6 A;  2ACT A;  4KLB A;  3S3R A;  2DCC A;  4MM3 B;  3AI8 A;  1VSN A;  1PIP A;  4K7C A;  5E6J A;  2DC6 A;  1K3B B;  4D8I A;  3D6S A;  3KSE A;  3P5V A;  2FYE A;  2BDL A;  1POP A;  1QXP A;  3BPF A;  2JTC A;  4AXL A;  1Y4H A;  2OUL A;  4BPV A;  3K9M A;  2NQI A;  2R9M A;  4A5U A;  1HUC B;  1X9Y A;  1PPP A;  4P6G A;  3I3T A;  4QH6 A;  2G8E A;  3OVX A;  1PBH A;  5JA7 A;  4GUA A;  4N4Z A;  4YYR A;  4PI3 A;  2Y5B A;  3KX1 A;  3PDF A;  4W5B A;  2DC9 A;  2XU3 A;  1UKF A;  4MSX A;  3PT2 A;  3WXE A;  2DZZ A;  3PRP A;  2P7U A;  3PBH A;  4AXM A;  3P5X A;  1YT7 A;  1BQI A;  5EZQ A;  5K16 A;  4CDC B;  4MI7 A;  1CB5 A;  1AU0 A;  2AVW A;  2XU5 A;  4D8E A;  1JQP A;  1EWL A;  3H6S A;  5CHV A;  2HHN A;  4DMY A;  2R9N A;  1CSB B;  3IEJ A;  2NQG A;  3O0U A;  2DC8 A;  4W4U A;  3GCB A;  3OQC A;  3BY4 A;  2BTW B;  1EWP A;  3TNX A;  5JZE A;  4I07 A;  2DOS A;  2E03 A;  3O65 A;  2G8J A;  2Z84 A;  3V6C A;  4IUM A;  4BOZ A;  4BOU A;  1U9Q X;  2CB5 A;  2DCB A;  3LXS A;  3PHW A;  3KWB X;  9PAP A;  4RF0 A;  1ITO A;  1QOL A;  1YAL A;  2R9C A;  2YJC A;  3BBA A;  1U5I A;  2AS8 A;  3BOW A;  3WXG A;  3BB7 A;  4BOS A;  5JH3 A;  2AUZ A;  1BY8 A;  2R9O A;  1NB3 A;  4RF1 A;  1MEG A;  1A6R A;  4YYS A;  1KFX L;  2JQG R;  4RNA A;  1AU4 A;  3KFQ A;  1PPN A;  1SP4 B;  2FTD A;  4WA6 A;  2PNS A;  3OIS A;  1ICF A;  1AYU A;  1PAD A;  3IMA A;  1MEM A;  4HXD B;  3W30 A;  3USV A;  1PPO A;  4QRX A;  2E00 A;  5CHT A;  1PVJ A;  5CVN B;  3HHI A;  3WXF A;  3P5W A;  4Q8G A;  4YYV A;  2J7Q A;  4REZ A;  1KHP A;  1PXV A;  2XU1 A;  3IV2 A;  2JQF R;  1TLO A;  2VHF A;  3K8U A;  4D8B A;  2P86 A;  4YV8 A;  3OF9 A;  4OVZ B;  4I05 A;  4PAD A;  3TRK A;  2P0R A;  3BWK A;  1F2C A;  2GHU A;  2E01 A;  2C0Y A; 
#chains in the Genus database with same CATH homology
 2B1N A;  2GFO A;  2R9F A;  1YVB A;  1NQC A;  4MZS A;  2FRQ A;  4BS5 A;  2AU1 A;  4FIP A;  4CDD B;  2F1G A;  1BGO A;  5F02 A;  4CDE B;  4BQV A;  5CVM A;  3LFY A;  2H7J A;  2O6X A;  3QT4 A;  2HXZ A;  1DEU A;  3PNR A;  4G54 A;  3V6E A;  4QBB A;  1W4T A;  4QRV A;  3N4C A;  2FRA A;  3CH3 X;  4GUZ A;  1EF7 A;  4YYQ A;  2ARY A;  1U9V A;  3RVW A;  3CH2 X;  1F29 A;  1KFU L;  2B1M A;  1TL9 A;  3N3K A;  2OZ2 A;  2DC7 A;  2NQA A;  1CVZ A;  5A24 A;  3RVX A;  3K24 A;  2VHS A;  3O1G A;  2PAD A;  1CV8 A;  2VFC A;  5J94 A;  3S3Q A;  2G7Y A;  1GLO A;  1O0E A;  2YJB A;  2FQ9 A;  3QJ3 A;  2AIM A;  2R6N A;  4I04 A;  3KWZ A;  1ATK A;  4ZUX U;  3ZUA A;  1MS6 A;  4RY2 A;  1ZCM A;  2WBF X;  8PCH A;  3B79 A;  1MHW A;  1GEC E;  1ME3 A;  2FT2 A;  1CJL A;  2DJF B;  4XUI A;  4YYU A;  1AEC A;  1MDW A;  1ME4 A;  2XU4 A;  4C5P A;  4BSQ A;  3MHH A;  3KW9 A;  1SNK A;  3M99 A;  4PP2 E;  1S4V A;  1MIR A;  3NHE A;  5FPW A;  1XKG A;  1YK8 A;  1NL6 A;  3CBK A;  3OF8 A;  1M6D A;  4YYW A;  2AYN A;  4CZW A;  4YVA A;  1VJV A;  3BCN A;  3H8B A;  2F7D A;  1F2A A;  1AU3 A;  3LTW A;  1AIM A;  2IBI A;  1IWD A;  2G6D A;  4N8W A;  3BC3 A;  6PAD A;  1AYV A;  3H8C A;  4DMX A;  3IOQ A;  1QMY A;  4BGF A;  1ZIV A;  2DCA A;  1NLJ A;  3F75 A;  2DCD A;  4BS6 A;  2BDZ A;  3MHS A;  3HD3 A;  1DF0 A;  1W5R A;  3HWN A;  3N3G A;  1CTE A;  1U9X A;  3P5U A;  4N79 A;  1NPZ A;  3OVZ A;  2FUD A;  3F5V A;  2CIO A;  7PCK A;  4NV8 A;  3H89 A;  4OEL A;  1NB5 A;  2IPP B;  3RVV A;  2E02 A;  2Y6E A;  1THE A;  4FK5 A;  2YJ8 A;  2HH5 A;  4QRG A;  4X6H A;  3QSD A;  1PCI A;  5CVO B;  1KHQ A;  2NQD B;  1BP4 A;  5EF4 A;  2HD5 A;  1FH0 A;  2OP3 A;  2YJ2 A;  1Y08 A;  3IHP A;  3CBJ A;  4Q8H A;  1AU2 A;  1CPJ A;  3C9E A;  3MOR A;  1U9W A;  1KXR A;  1EWO A;  2FO5 A;  3MTN A;  3KKU A;  1EWM A;  1Q6K A;  1QDQ A;  2ATO A;  4P6E A;  2AYO A;  2DJG B;  4X6J A;  3BPM A;  4MZO A;  1AYW A;  5EGW A;  4XR7 A;  1CS8 A;  1PPD A;  2PRE A;  1F2B A;  3ERV A;  2YJ9 A;  1TU6 A;  3I06 A;  3U8E A;  1YK7 A;  3HHA A;  4CDF B;  2PBH A;  3E1Z B;  4W5C A;  2DZY A;  4HWY A;  4X6I A;  1CQD A;  4FJC A;  2AUX A;  3PW3 A;  1GMY A;  4OEM A;  1STF E;  3IUT A;  3H7D A;  1E2T A;  5PAD A;  3DF0 A;  1GCB A;  4PP1 A;  1PE6 A;  2ACT A;  4KLB A;  3S3R A;  2DCC A;  3AI8 A;  1VSN A;  4B55 A;  1PIP A;  4K7C A;  2DC6 A;  1K3B B;  3D6S A;  3KSE A;  3P5V A;  2FYE A;  2BDL A;  1POP A;  1QXP A;  4NV7 A;  3BPF A;  4AXL A;  1Y4H A;  2OUL A;  4BPV A;  3K9M A;  2NQI A;  2R9M A;  1HUC B;  1X9Y A;  1PPP A;  4P6G A;  1W6F A;  3I3T A;  4QH6 A;  2G8E A;  3OVX A;  1PBH A;  5JA7 A;  4N4Z A;  4YYR A;  4PI3 A;  2Y5B A;  3KX1 A;  3PDF A;  4W5B A;  2DC9 A;  2XU3 A;  4MSX A;  3WXE A;  2DZZ A;  2P7U A;  3PBH A;  4AXM A;  3P5X A;  1YT7 A;  1BQI A;  5K16 A;  4CDC B;  1CB5 A;  1AU0 A;  2AVW A;  2XU5 A;  1JQP A;  1EWL A;  3H6S A;  5CHV A;  2HHN A;  4DMY A;  2R9N A;  1CSB B;  3IEJ A;  2NQG A;  3O0U A;  2DC8 A;  4W4U A;  3GCB A;  1EWP A;  3TNX A;  4I07 A;  2E03 A;  2G8J A;  3V6C A;  1U9Q X;  2CB5 A;  2DCB A;  3LXS A;  3KWB X;  9PAP A;  1ITO A;  1QOL A;  1YAL A;  2R9C A;  2YJC A;  1U5I A;  2VFB A;  2AS8 A;  3BOW A;  3WXG A;  5JH3 A;  2AUZ A;  1BY8 A;  2R9O A;  1NB3 A;  1MEG A;  1A6R A;  4YYS A;  1KFX L;  2JQG R;  1AU4 A;  3KFQ A;  1PPN A;  1SP4 B;  2FTD A;  1GX3 A;  4WA6 A;  2PNS A;  3OIS A;  1ICF A;  1AYU A;  1PAD A;  3IMA A;  1MEM A;  3USV A;  1PPO A;  4QRX A;  2E00 A;  5CHT A;  2BSZ A;  5CVN B;  3HHI A;  3WXF A;  3P5W A;  4Q8G A;  4YYV A;  1KHP A;  1PXV A;  2XU1 A;  3IV2 A;  2JQF R;  1TLO A;  2VHF A;  3D9W A;  3K8U A;  2P86 A;  4YV8 A;  3OF9 A;  4I05 A;  4PAD A;  2P0R A;  3BWK A;  1F2C A;  2GHU A;  2E01 A;  2C0Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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