2G8EA

Calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
326
structure length
326
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 100
structure length 326
sequence length 326
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8eA02
3IOQA 2BDZA 4YV8A 3CH3X 2G8JA 2F1GA 1KHPA 3RVWA 2YJ2A 1CVZA 4KLBA 3N3GA 4MSXA 1SP4B 4X6HA 1MEGA 4X6IA 3IEJA 3WXFA 4AXMA 1CSBB 1KXRA 3U8EA 4MZOA 1QDQA 3F75A 3P5UA 2FO5A 2AVWA 4N79A 3HHAA 2R9NA 2GHUA 4OELA 1AU2A 2HD5A 1PCIA 2G7YA 1MEMA 1NL6A 3DF0A 1EWMA 3KWBX 3S3QA 4I07A 5J94A 5A24A 2PADA 2FQ9A 2O6XA 1KFXL 3M99A 1MDWA 1ME4A 6PADA 3P5WA 2R9FA 2PNSA 1PPDA 1PBHA 1NB5A 3IMAA 1AU4A 1DF0A 2JQGR 1KFUL 2B1NA 1PIPA 3B79A 4Q8GA 3CBKA 2E01A 2DJFB 4YYSA 2Y6EA 2NQDB 1MHWA 1CQDA 2YJ9A 4YYUA 1EWOA 3PNRA 1TLOA 3O1GA 1AECA 1CV8A 3IUTA 4I04A 2AS8A 3KWZA 3LXSA 2AUXA 1AU0A 2YJ8A 1AYVA 4K7CA 2AYOA 1CS8A 4BPVA 2FRQA 4HWYA 4YYWA 1EWLA 4PP2E 2DZYA 5JH3A 3I3TA 3KX1A 1ICFA 1PE6A 1CTEA 3KKUA 2HXZA 1U9QX 2ARYA 2DZZA 2FTDA 1DEUA 8PCHA 1STFE 3PW3A 1ZCMA 1YK7A 1F2BA 1THEA 3KSEA 4XUIA 3TNXA 2R9CA 1TU6A 2F7DA 3K24A 4QRGA 3OVXA 1F2CA 3BC3A 3QJ3A 4FK5A 3WXEA 1BGOA 3H89A 4CDEB 2XU1A 4W4UA 3K8UA 2NQGA 1AYWA 2P7UA 1EF7A 2P86A 1YT7A 3IHPA 2XU5A 2NQIA 2YJCA 4X6JA 1EWPA 3HD3A 2HHNA 2R6NA 1TL9A 1NQCA 3ERVA 3RVVA 4YYQA 5FPWA 2ACTA 5CVNB 1BY8A 3KW9A 1FH0A 2G6DA 2CB5A 1YALA 2DCAA 5CVMA 1CJLA 3V6CA 1U9XA 5K16A 2IBIA 5EF4A 1HUCB 4QBBA 2AU1A 1ATKA 3ZUAA 1CPJA 5CVOB 2YJBA 2IPPB 3N3KA 4BS6A 4QH6A 1GECE 2VHSA 3KFQA 4PP1A 1GLOA 4QRXA 2E03A 3NHEA 1PPNA 3CBJA 1YK8A 2DCDA 3BPFA 1X9YA 1K3BB 3OF9A 5CHVA 2BDLA 4DMYA 4P6GA 1A6RA 2JQFR 3CH2X 4PADA 4BS5A 1O0EA 2DC9A 1Y4HA 3MTNA 7PCKA 3BCNA 1YVBA 1AU3A 4CDFB 1M6DA 1VSNA 3HWNA 4YVAA 2H7JA 4YYVA 3LFYA 5JA7A 2PREA 3BPMA 5F02A 3S3RA 2AUZA 1PPPA 3E1ZB 1BP4A 4W5CA 2DJGB 2DC7A 2E02A 1QMYA 2DC6A 2XU3A 1MS6A 1S4VA 2B1MA 3P5XA 1GCBA 2DCCA 2Y5BA 2XU4A 3RVXA 3D6SA 2C0YA 3BWKA 3OISA 2FT2A 1IWDA 2WBFX 1BQIA 3K9MA 4OEMA 3IV2A 3BOWA 1XKGA 2AYNA 3GCBA 1NPZA 3H8BA 3USVA 2OP3A 4PI3A 2P0RA 4BQVA 2E00A 3H7DA 1Q6KA 3V6EA 4RY2A 4P6EA 1QXPA 3N4CA 4N8WA 1F29A 2OZ2A 1Y08A 1ME3A 3H6SA 3P5VA 2HH5A 1MIRA 4DMXA 9PAPA 5CHTA 1ITOA 3HHIA 3QT4A 4FJCA 2DCBA 3OVZA 4I05A 1QOLA 3I06A 4AXLA 1JQPA 4MZSA 4QRVA 3MHSA 3H8CA 2DC8A 1NB3A 3WXGA 3MORA 1AYUA 4Q8HA 2FYEA 2AIMA 1POPA 1U9VA 1SNKA 1U5IA 1PPOA 5PADA 1PADA 4W5BA 4BSQA 2G8EA 3OF8A 4G54A 2GFOA 3PDFA 4XR7A 3C9EA 4CZWA 1AIMA 1KHQA 2OULA 3MHHA 3QSDA 1VJVA 3PBHA 4N4ZA 1U9WA 2CIOA 2ATOA 2R9MA 3F5VA 4CDCB 1PXVA 2R9OA 4FIPA 2FRAA 4ZUXU 2PBHA 3O0UA 2NQAA 3AI8A 2FUDA 1CB5A 1GMYA 1ZIVA 4CDDB 2VHFA 1F2AA 4WA6A 5EGWA 4YYRA 1NLJA
chains in the Genus database with same CATH superfamily
3IOQA 2BDZA 4YV8A 3CH3X 2G8JA 2F1GA 1KHPA 3RVWA 3PHWA 2YJ2A 1CVZA 4KLBA 3N3GA 4MSXA 1SP4B 4X6HA 1MEGA 4X6IA 3IEJA 3WXFA 4AXMA 1CSBB 1KXRA 3U8EA 4BOZA 4MZOA 1DKIA 1QDQA 3F75A 3P5UA 2FO5A 2AVWA 4N79A 3HHAA 4OW0A 3PRMA 2R9NA 2GHUA 4OELA 1AU2A 2HD5A 1PCIA 2G7YA 1MEMA 1NL6A 2J7QC 3DF0A 1EWMA 3KWBX 3S3QA 1PVJA 4I07A 5J94A 5A24A 2PADA 2FQ9A 2O6XA 4IUMA 1KFXL 3RNVA 3M99A 1MDWA 1ME4A 6PADA 3P5WA 2R9FA 3PRPA 2PNSA 1PPDA 1PBHA 4D8IA 1NB5A 3IMAA 1AU4A 1DF0A 2JQGR 1KFUL 2B1NA 1PIPA 3B79A 4P16A 4Q8GA 3CBKA 2AGAA 2E01A 2DJFB 4YYSA 2Y6EA 2NQDB 1MHWA 1CQDA 4M0WA 2YJ9A 4YYUA 1EWOA 3PNRA 1TLOA 3O1GA 4RF0A 1AECA 1CV8A 3IUTA 4PT5A 2JTCA 4I04A 2AS8A 4IP3A 3KWZA 3LXSA 3TRKA 4REZA 2AUXA 1AU0A 2YJ8A 1AYVA 4K7CA 2AYOA 4OVZB 1CS8A 4BPVA 3E9SA 2FRQA 4HWYA 4BOUA 4YYWA 1EWLA 4PP2E 2DZYA 5JH3A 3I3TA 3KX1A 1ICFA 1PE6A 2BU3A 1CTEA 3KKUA 3O65A 2HXZA 1U9QX 2ARYA 2DZZA 2FTDA 1DEUA 8PCHA 1STFE 3PW3A 5EZSA 3PHXA 1ZCMA 1YK7A 1F2BA 1THEA 3KSEA 5EZQA 4XUIA 3TNXA 2R9CA 1TU6A 2F7DA 3K24A 4QRGA 3OVXA 1F2CA 3BC3A 3QJ3A 4FK5A 3WXEA 1BGOA 3H89A 3OQCA 4CDEB 4A5UA 2XU1A 4W4UA 3K8UA 2NQGA 1AYWA 2P7UA 1EF7A 2P86A 1YT7A 3IHPA 2XU5A 2NQIA 2YJCA 4BOPA 4X6JA 1EWPA 3HD3A 2HHNA 4HXDB 2R6NA 1TL9A 1NQCA 3ERVA 3RVVA 4YYQA 5FPWA 2ACTA 5CVNB 2BTWA 1BY8A 3KW9A 1FH0A 2G6DA 2CB5A 2Z84A 1YALA 2DCAA 5CVMA 4BOQA 5KO3A 1CJLA 3V6CA 1U9XA 4ZTBA 5K16A 2IBIA 3BY4A 2BTWB 5EF4A 1HUCB 3W30A 4QBBA 2AU1A 1ATKA 3ZUAA 4MM3B 1CPJA 5CVOB 2YJBA 3MP2A 2IPPB 3N3KA 4BS6A 4QH6A 1GECE 2VHSA 3KFQA 4PP1A 1GLOA 4QRXA 2E03A 2JRIA 3NHEA 1PPNA 3MTVA 3CBJA 5JZEA 4OVZA 1YK8A 2DCDA 3BPFA 1X9YA 1K3BB 3OF9A 5CHVA 4XZXA 2BDLA 3MJ5A 4DMYA 4RNAA 4P6GA 1A6RA 2JQFR 3IFUA 3CH2X 3PSEA 4PADA 4BS5A 1O0EA 2DC9A 1Y4HA 3MTNA 7PCKA 3BCNA 1YVBA 1AU3A 4CDFB 1M6DA 1VSNA 3B21A 3HWNA 4YVAA 2H7JA 4YYVA 2FE8A 3LFYA 5JA7A 2PREA 3BPMA 5F02A 3S3RA 2AUZA 1PPPA 3E1ZB 2DOSA 1BP4A 4GUAA 4W5CA 2DJGB 2DC7A 2E02A 1QMYA 2DC6A 2XU3A 4D8EA 1MS6A 1S4VA 2B1MA 3P5XA 1GCBA 2DCCA 2Y5BA 2XU4A 3RVXA 3D6SA 2C0YA 3BWKA 3OISA 2FT2A 1IWDA 2WBFX 1BQIA 3K9MA 4OEMA 3IV2A 3TMPA 3BOWA 1XKGA 2AYNA 3GCBA 1NPZA 3H8BA 3USVA 2OP3A 4PI3A 2P0RA 4BQVA 2UZJA 2E00A 3H7DA 1Q6KA 3V6EA 4RY2A 4P6EA 1QXPA 3N4CA 4N8WA 3ZNHA 1F29A 2OZ2A 1Y08A 1ME3A 3H6SA 3P5VA 2HH5A 1UKFA 3C0RA 1MIRA 4DMXA 9PAPA 2J7QA 5CHTA 1ITOA 3HHIA 4WURA 3QT4A 4FJCA 3PT2A 2DCBA 3OVZA 4I05A 1QOLA 3I06A 4AXLA 1JQPA 4MZSA 4QRVA 3MHSA 3H8CA 4R3DA 2DC8A 1NB3A 3WXGA 3MORA 4RF1A 1AYUA 4Q8HA 2FYEA 2AIMA 3W31A 1POPA 1U9VA 3PHUA 1SNKA 1U5IA 1PPOA 3BBAA 4RKXA 5PADA 1PADA 4W5BA 4BSQA 2G8EA 3OF8A 4G54A 2GFOA 3PDFA 4XR7A 3C9EA 4CZWA 4BOSA 1AIMA 2HWKA 1KHQA 3BB7A 2OULA 3MHHA 3QSDA 1VJVA 4MI7A 3PBHA 4N4ZA 1U9WA 2CIOA 2ATOA 2R9MA 3F5VA 4CDCB 1PXVA 5E6JA 2R9OA 4FIPA 2FRAA 4ZUXU 2PBHA 4D8BA 3O0UA 2NQAA 3AI8A 2FUDA 1CB5A 1GMYA 1ZIVA 4CDDB 2VHFA 1F2AA 4WA6A 5EGWA 4YYRA 1YZBA 1NLJA
chains in the Genus database with same CATH topology
3IOQA 2BDZA 4YV8A 3CH3X 2G8JA 2F1GA 1KHPA 3RVWA 2YJ2A 1CVZA 4KLBA 3N3GA 4MSXA 1SP4B 4X6HA 1MEGA 4X6IA 3IEJA 3WXFA 4AXMA 1CSBB 1KXRA 3U8EA 4MZOA 1QDQA 3F75A 3P5UA 2FO5A 2AVWA 4N79A 3HHAA 4BGFA 2R9NA 2GHUA 4OELA 1AU2A 2HD5A 1PCIA 1W6FA 1MEMA 2G7YA 1NL6A 3D9WA 3DF0A 1EWMA 3KWBX 3S3QA 4I07A 5J94A 5A24A 2PADA 2FQ9A 2O6XA 1KFXL 3M99A 1MDWA 1ME4A 6PADA 3P5WA 2R9FA 2PNSA 1PPDA 1PBHA 1NB5A 3IMAA 1AU4A 1DF0A 2JQGR 1KFUL 2B1NA 1PIPA 3B79A 4Q8GA 3CBKA 2E01A 2DJFB 4YYSA 2Y6EA 2NQDB 1MHWA 1CQDA 2YJ9A 4YYUA 1EWOA 3PNRA 1TLOA 3O1GA 1AECA 1CV8A 3IUTA 4I04A 2AS8A 3KWZA 3LXSA 2AUXA 1AU0A 2VFCA 2YJ8A 1AYVA 4K7CA 2AYOA 2BSZA 1CS8A 4BPVA 2FRQA 4HWYA 4YYWA 1EWLA 4PP2E 2DZYA 5JH3A 3I3TA 3KX1A 1ICFA 1PE6A 1CTEA 3KKUA 2HXZA 1U9QX 2ARYA 2DZZA 2FTDA 1DEUA 8PCHA 1STFE 3PW3A 1ZCMA 4NV7A 1YK7A 1F2BA 1THEA 3KSEA 4XUIA 3TNXA 2R9CA 1TU6A 2F7DA 3K24A 4QRGA 3OVXA 1F2CA 4FK5A 3BC3A 3QJ3A 3WXEA 1BGOA 3H89A 4CDEB 2XU1A 4W4UA 3K8UA 2NQGA 1AYWA 2P7UA 1EF7A 2P86A 1YT7A 3IHPA 2XU5A 4C5PA 2NQIA 2YJCA 4X6JA 1EWPA 3HD3A 2HHNA 2R6NA 1TL9A 1NQCA 3ERVA 3RVVA 4YYQA 5FPWA 2ACTA 5CVNB 1BY8A 3KW9A 1FH0A 2G6DA 2CB5A 1YALA 2DCAA 5CVMA 1CJLA 3V6CA 1U9XA 5K16A 2IBIA 4GUZA 5EF4A 1HUCB 4QBBA 2AU1A 1ATKA 3ZUAA 1CPJA 5CVOB 2YJBA 2IPPB 3N3KA 4BS6A 4QH6A 1GECE 2VHSA 3KFQA 4PP1A 1GLOA 4QRXA 2E03A 3NHEA 1PPNA 3CBJA 1YK8A 2DCDA 3BPFA 1X9YA 1K3BB 3OF9A 5CHVA 4NV8A 1W4TA 2BDLA 4DMYA 4P6GA 1A6RA 2JQFR 3CH2X 4PADA 4BS5A 1O0EA 2DC9A 1Y4HA 3MTNA 7PCKA 4B55A 3BCNA 1YVBA 1AU3A 1GX3A 4CDFB 1M6DA 1VSNA 3LTWA 3HWNA 4YVAA 2H7JA 4YYVA 3LFYA 5JA7A 2PREA 3BPMA 5F02A 3S3RA 2AUZA 1PPPA 3E1ZB 1BP4A 4W5CA 2DJGB 2DC7A 2E02A 1QMYA 2DC6A 2XU3A 1MS6A 1S4VA 2B1MA 3P5XA 1GCBA 2DCCA 2Y5BA 2XU4A 3RVXA 3D6SA 2C0YA 3BWKA 1W5RA 3OISA 2FT2A 1IWDA 2WBFX 1BQIA 3K9MA 4OEMA 3IV2A 3BOWA 1XKGA 2AYNA 3GCBA 1NPZA 3H8BA 3USVA 2OP3A 4PI3A 2P0RA 4BQVA 2E00A 3H7DA 1Q6KA 3V6EA 4RY2A 4P6EA 1QXPA 3N4CA 4N8WA 1F29A 2OZ2A 1Y08A 1ME3A 3H6SA 3P5VA 2HH5A 1MIRA 4DMXA 9PAPA 5CHTA 1ITOA 3HHIA 3QT4A 4FJCA 2DCBA 3OVZA 4I05A 1QOLA 3I06A 4AXLA 1JQPA 4MZSA 4QRVA 3MHSA 3H8CA 2DC8A 1NB3A 3WXGA 3MORA 1AYUA 1E2TA 4Q8HA 2FYEA 2AIMA 1POPA 1U9VA 1SNKA 1U5IA 1PPOA 5PADA 1PADA 4W5BA 4BSQA 2G8EA 3OF8A 4G54A 2GFOA 3PDFA 4XR7A 3C9EA 4CZWA 1AIMA 1KHQA 2OULA 3MHHA 3QSDA 1VJVA 3PBHA 4N4ZA 1U9WA 2CIOA 2VFBA 2ATOA 2R9MA 3F5VA 4CDCB 1PXVA 2R9OA 4FIPA 2FRAA 4ZUXU 2PBHA 3O0UA 2NQAA 3AI8A 2FUDA 1CB5A 1GMYA 1ZIVA 4CDDB 2VHFA 1F2AA 4WA6A 5EGWA 4YYRA 1NLJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IOQ A;  2BDZ A;  4YV8 A;  3CH3 X;  2G8J A;  2F1G A;  1KHP A;  3RVW A;  2YJ2 A;  1CVZ A;  4KLB A;  3N3G A;  4MSX A;  1SP4 B;  4X6H A;  1MEG A;  4X6I A;  3IEJ A;  3WXF A;  4AXM A;  1CSB B;  1KXR A;  3U8E A;  4MZO A;  1QDQ A;  3F75 A;  3P5U A;  2FO5 A;  2AVW A;  4N79 A;  3HHA A;  2R9N A;  2GHU A;  4OEL A;  1AU2 A;  2HD5 A;  1PCI A;  2G7Y A;  1MEM A;  1NL6 A;  3DF0 A;  1EWM A;  3KWB X;  3S3Q A;  4I07 A;  5J94 A;  5A24 A;  2PAD A;  2FQ9 A;  2O6X A;  1KFX L;  3M99 A;  1MDW A;  1ME4 A;  6PAD A;  3P5W A;  2R9F A;  2PNS A;  1PPD A;  1PBH A;  1NB5 A;  3IMA A;  1AU4 A;  1DF0 A;  2JQG R;  1KFU L;  2B1N A;  1PIP A;  3B79 A;  4Q8G A;  3CBK A;  2E01 A;  2DJF B;  4YYS A;  2Y6E A;  2NQD B;  1MHW A;  1CQD A;  2YJ9 A;  4YYU A;  1EWO A;  3PNR A;  1TLO A;  3O1G A;  1AEC A;  1CV8 A;  3IUT A;  4I04 A;  2AS8 A;  3KWZ A;  3LXS A;  2AUX A;  1AU0 A;  2YJ8 A;  1AYV A;  4K7C A;  2AYO A;  1CS8 A;  4BPV A;  2FRQ A;  4HWY A;  4YYW A;  1EWL A;  4PP2 E;  2DZY A;  5JH3 A;  3I3T A;  3KX1 A;  1ICF A;  1PE6 A;  1CTE A;  3KKU A;  2HXZ A;  1U9Q X;  2ARY A;  2DZZ A;  2FTD A;  1DEU A;  8PCH A;  1STF E;  3PW3 A;  1ZCM A;  1YK7 A;  1F2B A;  1THE A;  3KSE A;  4XUI A;  3TNX A;  2R9C A;  1TU6 A;  2F7D A;  3K24 A;  4QRG A;  3OVX A;  1F2C A;  3BC3 A;  3QJ3 A;  4FK5 A;  3WXE A;  1BGO A;  3H89 A;  4CDE B;  2XU1 A;  4W4U A;  3K8U A;  2NQG A;  1AYW A;  2P7U A;  1EF7 A;  2P86 A;  1YT7 A;  3IHP A;  2XU5 A;  2NQI A;  2YJC A;  4X6J A;  1EWP A;  3HD3 A;  2HHN A;  2R6N A;  1TL9 A;  1NQC A;  3ERV A;  3RVV A;  4YYQ A;  5FPW A;  2ACT A;  5CVN B;  1BY8 A;  3KW9 A;  1FH0 A;  2G6D A;  2CB5 A;  1YAL A;  2DCA A;  5CVM A;  1CJL A;  3V6C A;  1U9X A;  5K16 A;  2IBI A;  5EF4 A;  1HUC B;  4QBB A;  2AU1 A;  1ATK A;  3ZUA A;  1CPJ A;  5CVO B;  2YJB A;  2IPP B;  3N3K A;  4BS6 A;  4QH6 A;  1GEC E;  2VHS A;  3KFQ A;  4PP1 A;  1GLO A;  4QRX A;  2E03 A;  3NHE A;  1PPN A;  3CBJ A;  1YK8 A;  2DCD A;  3BPF A;  1X9Y A;  1K3B B;  3OF9 A;  5CHV A;  2BDL A;  4DMY A;  4P6G A;  1A6R A;  2JQF R;  3CH2 X;  4PAD A;  4BS5 A;  1O0E A;  2DC9 A;  1Y4H A;  3MTN A;  7PCK A;  3BCN A;  1YVB A;  1AU3 A;  4CDF B;  1M6D A;  1VSN A;  3HWN A;  4YVA A;  2H7J A;  4YYV A;  3LFY A;  5JA7 A;  2PRE A;  3BPM A;  5F02 A;  3S3R A;  2AUZ A;  1PPP A;  3E1Z B;  1BP4 A;  4W5C A;  2DJG B;  2DC7 A;  2E02 A;  1QMY A;  2DC6 A;  2XU3 A;  1MS6 A;  1S4V A;  2B1M A;  3P5X A;  1GCB A;  2DCC A;  2Y5B A;  2XU4 A;  3RVX A;  3D6S A;  2C0Y A;  3BWK A;  3OIS A;  2FT2 A;  1IWD A;  2WBF X;  1BQI A;  3K9M A;  4OEM A;  3IV2 A;  3BOW A;  1XKG A;  2AYN A;  3GCB A;  1NPZ A;  3H8B A;  3USV A;  2OP3 A;  4PI3 A;  2P0R A;  4BQV A;  2E00 A;  3H7D A;  1Q6K A;  3V6E A;  4RY2 A;  4P6E A;  1QXP A;  3N4C A;  4N8W A;  1F29 A;  2OZ2 A;  1Y08 A;  1ME3 A;  3H6S A;  3P5V A;  2HH5 A;  1MIR A;  4DMX A;  9PAP A;  5CHT A;  1ITO A;  3HHI A;  3QT4 A;  4FJC A;  2DCB A;  3OVZ A;  4I05 A;  1QOL A;  3I06 A;  4AXL A;  1JQP A;  4MZS A;  4QRV A;  3MHS A;  3H8C A;  2DC8 A;  1NB3 A;  3WXG A;  3MOR A;  1AYU A;  4Q8H A;  2FYE A;  2AIM A;  1POP A;  1U9V A;  1SNK A;  1U5I A;  1PPO A;  5PAD A;  1PAD A;  4W5B A;  4BSQ A;  2G8E A;  3OF8 A;  4G54 A;  2GFO A;  3PDF A;  4XR7 A;  3C9E A;  4CZW A;  1AIM A;  1KHQ A;  2OUL A;  3MHH A;  3QSD A;  1VJV A;  3PBH A;  4N4Z A;  1U9W A;  2CIO A;  2ATO A;  2R9M A;  3F5V A;  4CDC B;  1PXV A;  2R9O A;  4FIP A;  2FRA A;  4ZUX U;  2PBH A;  3O0U A;  2NQA A;  3AI8 A;  2FUD A;  1CB5 A;  1GMY A;  1ZIV A;  4CDD B;  2VHF A;  1F2A A;  4WA6 A;  5EGW A;  4YYR A;  1NLJ A; 
#chains in the Genus database with same CATH topology
 3IOQ A;  2BDZ A;  4YV8 A;  3CH3 X;  2G8J A;  2F1G A;  1KHP A;  3RVW A;  3PHW A;  2YJ2 A;  1CVZ A;  4KLB A;  3N3G A;  4MSX A;  1SP4 B;  4X6H A;  1MEG A;  4X6I A;  3IEJ A;  3WXF A;  4AXM A;  1CSB B;  1KXR A;  3U8E A;  4BOZ A;  4MZO A;  1DKI A;  1QDQ A;  3F75 A;  3P5U A;  2FO5 A;  2AVW A;  4N79 A;  3HHA A;  4OW0 A;  3PRM A;  2R9N A;  2GHU A;  4OEL A;  1AU2 A;  2HD5 A;  1PCI A;  2G7Y A;  1MEM A;  1NL6 A;  2J7Q C;  3DF0 A;  1EWM A;  3KWB X;  3S3Q A;  1PVJ A;  4I07 A;  5J94 A;  5A24 A;  2PAD A;  2FQ9 A;  2O6X A;  4IUM A;  1KFX L;  3RNV A;  3M99 A;  1MDW A;  1ME4 A;  6PAD A;  3P5W A;  2R9F A;  3PRP A;  2PNS A;  1PPD A;  1PBH A;  4D8I A;  1NB5 A;  3IMA A;  1AU4 A;  1DF0 A;  2JQG R;  1KFU L;  2B1N A;  1PIP A;  3B79 A;  4P16 A;  4Q8G A;  3CBK A;  2AGA A;  2E01 A;  2DJF B;  4YYS A;  2Y6E A;  2NQD B;  1MHW A;  1CQD A;  4M0W A;  2YJ9 A;  4YYU A;  1EWO A;  3PNR A;  1TLO A;  3O1G A;  4RF0 A;  1AEC A;  1CV8 A;  3IUT A;  4PT5 A;  2JTC A;  4I04 A;  2AS8 A;  4IP3 A;  3KWZ A;  3LXS A;  3TRK A;  4REZ A;  2AUX A;  1AU0 A;  2YJ8 A;  1AYV A;  4K7C A;  2AYO A;  4OVZ B;  1CS8 A;  4BPV A;  3E9S A;  2FRQ A;  4HWY A;  4BOU A;  4YYW A;  1EWL A;  4PP2 E;  2DZY A;  5JH3 A;  3I3T A;  3KX1 A;  1ICF A;  1PE6 A;  2BU3 A;  1CTE A;  3KKU A;  3O65 A;  2HXZ A;  1U9Q X;  2ARY A;  2DZZ A;  2FTD A;  1DEU A;  8PCH A;  1STF E;  3PW3 A;  5EZS A;  3PHX A;  1ZCM A;  1YK7 A;  1F2B A;  1THE A;  3KSE A;  5EZQ A;  4XUI A;  3TNX A;  2R9C A;  1TU6 A;  2F7D A;  3K24 A;  4QRG A;  3OVX A;  1F2C A;  3BC3 A;  3QJ3 A;  4FK5 A;  3WXE A;  1BGO A;  3H89 A;  3OQC A;  4CDE B;  4A5U A;  2XU1 A;  4W4U A;  3K8U A;  2NQG A;  1AYW A;  2P7U A;  1EF7 A;  2P86 A;  1YT7 A;  3IHP A;  2XU5 A;  2NQI A;  2YJC A;  4BOP A;  4X6J A;  1EWP A;  3HD3 A;  2HHN A;  4HXD B;  2R6N A;  1TL9 A;  1NQC A;  3ERV A;  3RVV A;  4YYQ A;  5FPW A;  2ACT A;  5CVN B;  2BTW A;  1BY8 A;  3KW9 A;  1FH0 A;  2G6D A;  2CB5 A;  2Z84 A;  1YAL A;  2DCA A;  5CVM A;  4BOQ A;  5KO3 A;  1CJL A;  3V6C A;  1U9X A;  4ZTB A;  5K16 A;  2IBI A;  3BY4 A;  2BTW B;  5EF4 A;  1HUC B;  3W30 A;  4QBB A;  2AU1 A;  1ATK A;  3ZUA A;  4MM3 B;  1CPJ A;  5CVO B;  2YJB A;  3MP2 A;  2IPP B;  3N3K A;  4BS6 A;  4QH6 A;  1GEC E;  2VHS A;  3KFQ A;  4PP1 A;  1GLO A;  4QRX A;  2E03 A;  2JRI A;  3NHE A;  1PPN A;  3MTV A;  3CBJ A;  5JZE A;  4OVZ A;  1YK8 A;  2DCD A;  3BPF A;  1X9Y A;  1K3B B;  3OF9 A;  5CHV A;  4XZX A;  2BDL A;  3MJ5 A;  4DMY A;  4RNA A;  4P6G A;  1A6R A;  2JQF R;  3IFU A;  3CH2 X;  3PSE A;  4PAD A;  4BS5 A;  1O0E A;  2DC9 A;  1Y4H A;  3MTN A;  7PCK A;  3BCN A;  1YVB A;  1AU3 A;  4CDF B;  1M6D A;  1VSN A;  3B21 A;  3HWN A;  4YVA A;  2H7J A;  4YYV A;  2FE8 A;  3LFY A;  5JA7 A;  2PRE A;  3BPM A;  5F02 A;  3S3R A;  2AUZ A;  1PPP A;  3E1Z B;  2DOS A;  1BP4 A;  4GUA A;  4W5C A;  2DJG B;  2DC7 A;  2E02 A;  1QMY A;  2DC6 A;  2XU3 A;  4D8E A;  1MS6 A;  1S4V A;  2B1M A;  3P5X A;  1GCB A;  2DCC A;  2Y5B A;  2XU4 A;  3RVX A;  3D6S A;  2C0Y A;  3BWK A;  3OIS A;  2FT2 A;  1IWD A;  2WBF X;  1BQI A;  3K9M A;  4OEM A;  3IV2 A;  3TMP A;  3BOW A;  1XKG A;  2AYN A;  3GCB A;  1NPZ A;  3H8B A;  3USV A;  2OP3 A;  4PI3 A;  2P0R A;  4BQV A;  2UZJ A;  2E00 A;  3H7D A;  1Q6K A;  3V6E A;  4RY2 A;  4P6E A;  1QXP A;  3N4C A;  4N8W A;  3ZNH A;  1F29 A;  2OZ2 A;  1Y08 A;  1ME3 A;  3H6S A;  3P5V A;  2HH5 A;  1UKF A;  3C0R A;  1MIR A;  4DMX A;  9PAP A;  2J7Q A;  5CHT A;  1ITO A;  3HHI A;  4WUR A;  3QT4 A;  4FJC A;  3PT2 A;  2DCB A;  3OVZ A;  4I05 A;  1QOL A;  3I06 A;  4AXL A;  1JQP A;  4MZS A;  4QRV A;  3MHS A;  3H8C A;  4R3D A;  2DC8 A;  1NB3 A;  3WXG A;  3MOR A;  4RF1 A;  1AYU A;  4Q8H A;  2FYE A;  2AIM A;  3W31 A;  1POP A;  1U9V A;  3PHU A;  1SNK A;  1U5I A;  1PPO A;  3BBA A;  4RKX A;  5PAD A;  1PAD A;  4W5B A;  4BSQ A;  2G8E A;  3OF8 A;  4G54 A;  2GFO A;  3PDF A;  4XR7 A;  3C9E A;  4CZW A;  4BOS A;  1AIM A;  2HWK A;  1KHQ A;  3BB7 A;  2OUL A;  3MHH A;  3QSD A;  1VJV A;  4MI7 A;  3PBH A;  4N4Z A;  1U9W A;  2CIO A;  2ATO A;  2R9M A;  3F5V A;  4CDC B;  1PXV A;  5E6J A;  2R9O A;  4FIP A;  2FRA A;  4ZUX U;  2PBH A;  4D8B A;  3O0U A;  2NQA A;  3AI8 A;  2FUD A;  1CB5 A;  1GMY A;  1ZIV A;  4CDD B;  2VHF A;  1F2A A;  4WA6 A;  5EGW A;  4YYR A;  1YZB A;  1NLJ A; 
#chains in the Genus database with same CATH homology
 3IOQ A;  2BDZ A;  4YV8 A;  3CH3 X;  2G8J A;  2F1G A;  1KHP A;  3RVW A;  2YJ2 A;  1CVZ A;  4KLB A;  3N3G A;  4MSX A;  1SP4 B;  4X6H A;  1MEG A;  4X6I A;  3IEJ A;  3WXF A;  4AXM A;  1CSB B;  1KXR A;  3U8E A;  4MZO A;  1QDQ A;  3F75 A;  3P5U A;  2FO5 A;  2AVW A;  4N79 A;  3HHA A;  4BGF A;  2R9N A;  2GHU A;  4OEL A;  1AU2 A;  2HD5 A;  1PCI A;  1W6F A;  1MEM A;  2G7Y A;  1NL6 A;  3D9W A;  3DF0 A;  1EWM A;  3KWB X;  3S3Q A;  4I07 A;  5J94 A;  5A24 A;  2PAD A;  2FQ9 A;  2O6X A;  1KFX L;  3M99 A;  1MDW A;  1ME4 A;  6PAD A;  3P5W A;  2R9F A;  2PNS A;  1PPD A;  1PBH A;  1NB5 A;  3IMA A;  1AU4 A;  1DF0 A;  2JQG R;  1KFU L;  2B1N A;  1PIP A;  3B79 A;  4Q8G A;  3CBK A;  2E01 A;  2DJF B;  4YYS A;  2Y6E A;  2NQD B;  1MHW A;  1CQD A;  2YJ9 A;  4YYU A;  1EWO A;  3PNR A;  1TLO A;  3O1G A;  1AEC A;  1CV8 A;  3IUT A;  4I04 A;  2AS8 A;  3KWZ A;  3LXS A;  2AUX A;  1AU0 A;  2VFC A;  2YJ8 A;  1AYV A;  4K7C A;  2AYO A;  2BSZ A;  1CS8 A;  4BPV A;  2FRQ A;  4HWY A;  4YYW A;  1EWL A;  4PP2 E;  2DZY A;  5JH3 A;  3I3T A;  3KX1 A;  1ICF A;  1PE6 A;  1CTE A;  3KKU A;  2HXZ A;  1U9Q X;  2ARY A;  2DZZ A;  2FTD A;  1DEU A;  8PCH A;  1STF E;  3PW3 A;  1ZCM A;  4NV7 A;  1YK7 A;  1F2B A;  1THE A;  3KSE A;  4XUI A;  3TNX A;  2R9C A;  1TU6 A;  2F7D A;  3K24 A;  4QRG A;  3OVX A;  1F2C A;  4FK5 A;  3BC3 A;  3QJ3 A;  3WXE A;  1BGO A;  3H89 A;  4CDE B;  2XU1 A;  4W4U A;  3K8U A;  2NQG A;  1AYW A;  2P7U A;  1EF7 A;  2P86 A;  1YT7 A;  3IHP A;  2XU5 A;  4C5P A;  2NQI A;  2YJC A;  4X6J A;  1EWP A;  3HD3 A;  2HHN A;  2R6N A;  1TL9 A;  1NQC A;  3ERV A;  3RVV A;  4YYQ A;  5FPW A;  2ACT A;  5CVN B;  1BY8 A;  3KW9 A;  1FH0 A;  2G6D A;  2CB5 A;  1YAL A;  2DCA A;  5CVM A;  1CJL A;  3V6C A;  1U9X A;  5K16 A;  2IBI A;  4GUZ A;  5EF4 A;  1HUC B;  4QBB A;  2AU1 A;  1ATK A;  3ZUA A;  1CPJ A;  5CVO B;  2YJB A;  2IPP B;  3N3K A;  4BS6 A;  4QH6 A;  1GEC E;  2VHS A;  3KFQ A;  4PP1 A;  1GLO A;  4QRX A;  2E03 A;  3NHE A;  1PPN A;  3CBJ A;  1YK8 A;  2DCD A;  3BPF A;  1X9Y A;  1K3B B;  3OF9 A;  5CHV A;  4NV8 A;  1W4T A;  2BDL A;  4DMY A;  4P6G A;  1A6R A;  2JQF R;  3CH2 X;  4PAD A;  4BS5 A;  1O0E A;  2DC9 A;  1Y4H A;  3MTN A;  7PCK A;  4B55 A;  3BCN A;  1YVB A;  1AU3 A;  1GX3 A;  4CDF B;  1M6D A;  1VSN A;  3LTW A;  3HWN A;  4YVA A;  2H7J A;  4YYV A;  3LFY A;  5JA7 A;  2PRE A;  3BPM A;  5F02 A;  3S3R A;  2AUZ A;  1PPP A;  3E1Z B;  1BP4 A;  4W5C A;  2DJG B;  2DC7 A;  2E02 A;  1QMY A;  2DC6 A;  2XU3 A;  1MS6 A;  1S4V A;  2B1M A;  3P5X A;  1GCB A;  2DCC A;  2Y5B A;  2XU4 A;  3RVX A;  3D6S A;  2C0Y A;  3BWK A;  1W5R A;  3OIS A;  2FT2 A;  1IWD A;  2WBF X;  1BQI A;  3K9M A;  4OEM A;  3IV2 A;  3BOW A;  1XKG A;  2AYN A;  3GCB A;  1NPZ A;  3H8B A;  3USV A;  2OP3 A;  4PI3 A;  2P0R A;  4BQV A;  2E00 A;  3H7D A;  1Q6K A;  3V6E A;  4RY2 A;  4P6E A;  1QXP A;  3N4C A;  4N8W A;  1F29 A;  2OZ2 A;  1Y08 A;  1ME3 A;  3H6S A;  3P5V A;  2HH5 A;  1MIR A;  4DMX A;  9PAP A;  5CHT A;  1ITO A;  3HHI A;  3QT4 A;  4FJC A;  2DCB A;  3OVZ A;  4I05 A;  1QOL A;  3I06 A;  4AXL A;  1JQP A;  4MZS A;  4QRV A;  3MHS A;  3H8C A;  2DC8 A;  1NB3 A;  3WXG A;  3MOR A;  1AYU A;  1E2T A;  4Q8H A;  2FYE A;  2AIM A;  1POP A;  1U9V A;  1SNK A;  1U5I A;  1PPO A;  5PAD A;  1PAD A;  4W5B A;  4BSQ A;  2G8E A;  3OF8 A;  4G54 A;  2GFO A;  3PDF A;  4XR7 A;  3C9E A;  4CZW A;  1AIM A;  1KHQ A;  2OUL A;  3MHH A;  3QSD A;  1VJV A;  3PBH A;  4N4Z A;  1U9W A;  2CIO A;  2VFB A;  2ATO A;  2R9M A;  3F5V A;  4CDC B;  1PXV A;  2R9O A;  4FIP A;  2FRA A;  4ZUX U;  2PBH A;  3O0U A;  2NQA A;  3AI8 A;  2FUD A;  1CB5 A;  1GMY A;  1ZIV A;  4CDD B;  2VHF A;  1F2A A;  4WA6 A;  5EGW A;  4YYR A;  1NLJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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