2H7JA

Crystal structure of cathepsin s in complex with a nonpeptidic inhibitor.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
218
structure length
218
Chain Sequence
ILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method.
pubmed doi rcsb
molecule keywords Cathepsin S
total genus 70
structure length 218
sequence length 218
chains with identical sequence B
ec nomenclature ec 3.4.22.27: Cathepsin S.
pdb deposition date 2006-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2h7jA00
3IUTA 4W4UA 4X6HA 4YYWA 3LFYA 1CQDA 4QRXA 2G7YA 3P5VA 3PNRA 3HHIA 3BOWA 5CHVA 1U5IA 3H6SA 2DZZA 1O0EA 2R9CA 2HHNA 1THEA 2YJ9A 3KKUA 2NQIA 3O0UA 3B79A 2GFOA 3WXGA 4YV8A 3K8UA 1BY8A 3CH2X 2P0RA 2E03A 1PIPA 4OELA 4X6JA 3IMAA 3BPFA 1U9XA 4CDEB 4DMXA 2O6XA 1PPDA 1AU3A 3U8EA 1YT7A 2HXZA 3N3KA 3ERVA 1U9VA 3BWKA 4AXLA 2VHSA 5JA7A 3USVA 4BPVA 4K7CA 2AYNA 4PP1A 4I05A 3IV2A 4QRGA 1CS8A 1NQCA 2AVWA 2CB5A 3O1GA 4MSXA 3BC3A 3H7DA 1U9WA 3OVXA 4P6GA 1EWLA 2NQGA 1VSNA 2YJCA 3K9MA 3V6CA 2F1GA 3HD3A 4CDCB 2B1NA 3QSDA 1ATKA 1BP4A 1F2CA 2P7UA 2R9NA 2AUZA 3H89A 1MDWA 3K24A 1CPJA 1JQPA 1PPPA 2AU1A 2G6DA 1AYWA 1KFXL 2R9FA 3P5UA 4I04A 2HH5A 2DC8A 2G8EA 3V6EA 1CSBB 3PDFA 4P6EA 3D6SA 3F75A 1SNKA 2ARYA 1SP4B 4KLBA 1EWOA 2DJFB 1QMYA 1S4VA 2Y6EA 3N4CA 2DC7A 2E01A 1U9QX 5CVMA 2FYEA 2DC6A 1F2BA 1HUCB 3MHSA 2GHUA 4YYVA 1K3BB 1ZCMA 3IOQA 3H8CA 2DCBA 4FIPA 3QT4A 2FTDA 4X6IA 5K16A 1CJLA 1YK7A 5EGWA 5CVNB 1YK8A 2H7JA 3RVXA 2DCAA 4G54A 1NL6A 4YYQA 2DZYA 5J94A 2VHFA 3S3RA 4W5BA 1X9YA 2IPPB 1AU4A 1STFE 1PE6A 2FT2A 4N4ZA 2OULA 3PBHA 1ME4A 4XR7A 2P86A 2AIMA 4CDDB 1YALA 1ICFA 2E02A 4QH6A 3CH3X 1PPNA 2PNSA 4YVAA 1KHQA 2PREA 4XUIA 2DCDA 3DF0A 1KHPA 4W5CA 1MEGA 1AU2A 1CB5A 3NHEA 1Y08A 3GCBA 1DF0A 3MORA 3QJ3A 2XU4A 3HWNA 1QDQA 4CZWA 4ZUXU 2DC9A 1PXVA 2B1MA 4RY2A 2AUXA 2NQDB 3KX1A 1NPZA 3PW3A 2R6NA 4QBBA 3KFQA 1TL9A 8PCHA 4Q8GA 3OVZA 4YYSA 3BCNA 1CVZA 3BPMA 3N3GA 1QXPA 1TU6A 3AI8A 4YYRA 3I3TA 2XU3A 3MHHA 1FH0A 1GLOA 4AXMA 1GECE 4N8WA 1F2AA 2PADA 4Q8HA 1YVBA 1M6DA 1PCIA 1NLJA 2CIOA 2ACTA 4WA6A 5A24A 1EWPA 2BDLA 2DJGB 4MZSA 2BDZA 1ZIVA 4FJCA 2C0YA 2Y5BA 3KWZA 2JQFR 1VJVA 3I06A 2OP3A 1MIRA 3M99A 1Q6KA 2WBFX 1PADA 4YYUA 3IHPA 2OZ2A 3OF8A 2FQ9A 2FUDA 1AYUA 2DCCA 1NB3A 3P5WA 4BS6A 1CV8A 2YJ8A 1F29A 4I07A 1EF7A 3KWBX 1DEUA 7PCKA 3E1ZB 1POPA 5CVOB 3WXEA 4N79A 5FPWA 1AECA 3IEJA 2ATOA 3C9EA 2HD5A 2R9MA 1KXRA 1PPOA 1Y4HA 1PBHA 4BS5A 3WXFA 4DMYA 9PAPA 1A6RA 3LXSA 3S3QA 3RVWA 1AU0A 3RVVA 2AYOA 2PBHA 3H8BA 4BQVA 1MEMA 5EF4A 2G8JA 3CBKA 1BQIA 1MHWA 1TLOA 1ME3A 1MS6A 5CHTA 1GCBA 2FO5A 1EWMA 2XU1A 2YJ2A 1IWDA 1QOLA 3KSEA 4PI3A 3HHAA 1KFUL 2FRQA 2NQAA 5PADA 2JQGR 3CBJA 3MTNA 2YJBA 2F7DA 1AIMA 1ITOA 4OEMA 3F5VA 1BGOA 2E00A 3KW9A 6PADA 2AS8A 4PP2E 2IBIA 4FK5A 3ZUAA 1CTEA 3OISA 2FRAA 3P5XA 1AYVA 5F02A 5JH3A 3OF9A 4MZOA 2R9OA 1GMYA 4BSQA 1XKGA 2XU5A 3TNXA 4PADA 4HWYA 1NB5A 4QRVA 4CDFB
chains in the Genus database with same CATH superfamily
3IUTA 4W4UA 3PT2A 4X6HA 4YYWA 1YZBA 3LFYA 1CQDA 4D8EA 4QRXA 2G7YA 3P5VA 3PNRA 3HHIA 3BOWA 5CHVA 1U5IA 3H6SA 2DZZA 1O0EA 2R9CA 4HXDB 2HHNA 1THEA 3C0RA 4MM3B 2YJ9A 3KKUA 2NQIA 3O0UA 3B79A 2GFOA 4IUMA 3OQCA 4REZA 3WXGA 3ZNHA 4M0WA 4YV8A 3K8UA 3MP2A 1BY8A 3CH2X 2P0RA 2E03A 1PIPA 4OELA 4OVZA 4X6JA 3IMAA 3BPFA 1U9XA 4CDEB 4DMXA 2O6XA 1PPDA 1AU3A 3U8EA 1YT7A 2HXZA 3N3KA 3PRMA 3ERVA 1U9VA 4PT5A 3BWKA 4AXLA 4RF0A 2VHSA 5JA7A 3USVA 4BPVA 4K7CA 2AYNA 4PP1A 2JRIA 4I05A 3IV2A 1PVJA 4QRGA 1CS8A 1NQCA 2AVWA 2CB5A 3O1GA 4MSXA 3BC3A 3PSEA 3H7DA 1U9WA 4R3DA 3OVXA 4P6GA 2J7QC 1EWLA 2NQGA 1VSNA 2J7QA 2YJCA 3K9MA 4D8BA 3V6CA 2F1GA 2BTWA 3HD3A 4CDCB 2B1NA 3QSDA 1ATKA 1BP4A 1F2CA 2P7UA 2R9NA 4MI7A 2AUZA 3H89A 1MDWA 3K24A 1CPJA 3RNVA 1JQPA 1PPPA 2AU1A 2G6DA 1AYWA 1KFXL 2R9FA 4BOSA 3TMPA 3P5UA 4I04A 2HH5A 4GUAA 4OVZB 2DC8A 2G8EA 3V6EA 1CSBB 3PDFA 4P6EA 3D6SA 3F75A 1SNKA 4XZXA 2ARYA 1SP4B 4KLBA 1EWOA 2DJFB 5EZSA 1QMYA 1S4VA 2Y6EA 3N4CA 2DC7A 4P16A 2E01A 1U9QX 5CVMA 2FYEA 4BOQA 2DC6A 1F2BA 1HUCB 3MJ5A 3MHSA 2GHUA 4YYVA 4RKXA 1K3BB 1ZCMA 3IOQA 3H8CA 2DCBA 4FIPA 3QT4A 2FTDA 4X6IA 4BOPA 5K16A 1CJLA 4A5UA 1YK7A 5EGWA 5CVNB 1YK8A 2H7JA 3RVXA 2DCAA 4G54A 3W31A 1NL6A 4YYQA 1DKIA 2DZYA 5J94A 2VHFA 2AGAA 2BTWB 3S3RA 4W5BA 1X9YA 2IPPB 3PHXA 4WURA 1AU4A 1STFE 1PE6A 5KO3A 2FT2A 4N4ZA 2OULA 3PBHA 1ME4A 4OW0A 4XR7A 2P86A 2AIMA 4CDDB 1YALA 1ICFA 2E02A 4QH6A 3CH3X 1PPNA 2PNSA 3BB7A 4YVAA 1KHQA 2PREA 4XUIA 2DCDA 3DF0A 1KHPA 4W5CA 1MEGA 1AU2A 1CB5A 4BOUA 3NHEA 3E9SA 1Y08A 3GCBA 3PHUA 1DF0A 3MORA 3QJ3A 2XU4A 3HWNA 1QDQA 4CZWA 4ZUXU 2DC9A 1PXVA 2B1MA 4RY2A 2AUXA 2NQDB 3KX1A 1NPZA 3W30A 2UZJA 3PW3A 2DOSA 2R6NA 4QBBA 3KFQA 1TL9A 8PCHA 4Q8GA 3OVZA 4YYSA 3BCNA 1CVZA 3BPMA 3MTVA 3N3GA 1QXPA 1TU6A 3AI8A 4YYRA 3I3TA 2XU3A 2JTCA 3MHHA 1FH0A 1GLOA 4AXMA 1GECE 4N8WA 1F2AA 2PADA 4Q8HA 1YVBA 1M6DA 1PCIA 1NLJA 2FE8A 2CIOA 1UKFA 2ACTA 3IFUA 4WA6A 5A24A 1EWPA 2BDLA 5EZQA 2DJGB 4MZSA 3PHWA 2BDZA 1ZIVA 4FJCA 2C0YA 2Y5BA 3KWZA 2JQFR 1VJVA 3I06A 2OP3A 4IP3A 1MIRA 3BBAA 3M99A 1Q6KA 2WBFX 2BU3A 1PADA 4YYUA 3IHPA 2OZ2A 3OF8A 2FQ9A 3TRKA 2FUDA 1AYUA 2DCCA 1NB3A 3P5WA 4BS6A 1CV8A 2YJ8A 1F29A 4I07A 1EF7A 4RF1A 3KWBX 4ZTBA 1DEUA 7PCKA 3E1ZB 1POPA 5CVOB 3WXEA 5E6JA 4N79A 5FPWA 1AECA 3IEJA 2ATOA 3BY4A 3C9EA 2HD5A 3B21A 2R9MA 1KXRA 1PPOA 1Y4HA 1PBHA 4BS5A 3WXFA 4DMYA 9PAPA 1A6RA 3LXSA 2Z84A 3S3QA 3RVWA 1AU0A 3RVVA 2AYOA 2PBHA 2HWKA 3H8BA 4BQVA 1MEMA 5EF4A 2G8JA 3CBKA 1BQIA 1MHWA 1TLOA 1ME3A 1MS6A 5CHTA 1GCBA 2FO5A 1EWMA 2XU1A 2YJ2A 1IWDA 1QOLA 3KSEA 4PI3A 3HHAA 4BOZA 1KFUL 3O65A 2FRQA 2NQAA 5PADA 2JQGR 3CBJA 3MTNA 2YJBA 2F7DA 1AIMA 1ITOA 4OEMA 3F5VA 1BGOA 2E00A 3PRPA 3KW9A 6PADA 4RNAA 2AS8A 4PP2E 2IBIA 4FK5A 3ZUAA 1CTEA 3OISA 4D8IA 2FRAA 3P5XA 1AYVA 5F02A 5JH3A 3OF9A 5JZEA 4MZOA 2R9OA 1GMYA 4BSQA 1XKGA 2XU5A 3TNXA 4PADA 4HWYA 1NB5A 4QRVA 4CDFB
chains in the Genus database with same CATH topology
3IUTA 4W4UA 4X6HA 4YYWA 3LFYA 1CQDA 4QRXA 2G7YA 3P5VA 3PNRA 3HHIA 3BOWA 5CHVA 1U5IA 3H6SA 2DZZA 1O0EA 2R9CA 2HHNA 1THEA 2YJ9A 3KKUA 2NQIA 3O0UA 3B79A 2GFOA 3WXGA 4YV8A 3K8UA 1BY8A 3CH2X 2P0RA 2E03A 1PIPA 4OELA 4X6JA 3IMAA 3BPFA 1U9XA 1W4TA 4CDEB 4DMXA 2O6XA 1PPDA 1AU3A 3U8EA 1YT7A 2HXZA 3N3KA 3ERVA 1U9VA 3BWKA 4AXLA 2VHSA 5JA7A 3USVA 4BPVA 4K7CA 2AYNA 4PP1A 4I05A 3IV2A 4QRGA 1CS8A 1NQCA 2AVWA 2CB5A 3O1GA 4MSXA 3BC3A 3H7DA 1U9WA 3OVXA 4P6GA 1EWLA 2NQGA 1VSNA 2YJCA 3K9MA 3V6CA 2F1GA 3HD3A 4CDCB 2B1NA 3QSDA 1ATKA 1BP4A 1F2CA 2P7UA 2R9NA 2AUZA 3H89A 1MDWA 3K24A 1CPJA 1JQPA 1PPPA 2AU1A 2G6DA 1AYWA 1KFXL 2R9FA 4B55A 1GX3A 3P5UA 4I04A 2HH5A 2DC8A 2G8EA 3V6EA 1CSBB 3PDFA 4P6EA 3D6SA 3F75A 1SNKA 2ARYA 1SP4B 4KLBA 1EWOA 2DJFB 1QMYA 1S4VA 2Y6EA 3N4CA 2DC7A 2E01A 1U9QX 5CVMA 2FYEA 2DC6A 1F2BA 1HUCB 3MHSA 2GHUA 4YYVA 1E2TA 4BGFA 1K3BB 1ZCMA 3IOQA 3H8CA 2DCBA 4FIPA 3QT4A 2FTDA 4X6IA 5K16A 1CJLA 1YK7A 5EGWA 5CVNB 1YK8A 2H7JA 3RVXA 2DCAA 4G54A 1NL6A 4YYQA 2BSZA 2DZYA 5J94A 2VHFA 3S3RA 4W5BA 1X9YA 2IPPB 1AU4A 1STFE 1PE6A 2FT2A 4N4ZA 2OULA 3PBHA 1ME4A 4XR7A 2P86A 2AIMA 4CDDB 1YALA 1ICFA 2E02A 4QH6A 3CH3X 1PPNA 2PNSA 4YVAA 1KHQA 2PREA 4XUIA 2DCDA 3DF0A 1KHPA 4W5CA 1MEGA 1AU2A 1CB5A 3NHEA 1W6FA 1Y08A 3GCBA 1DF0A 3MORA 3QJ3A 2XU4A 3HWNA 1QDQA 4CZWA 4ZUXU 2DC9A 1PXVA 2B1MA 4RY2A 2AUXA 2NQDB 3KX1A 1NPZA 3D9WA 3PW3A 2R6NA 4QBBA 3KFQA 1TL9A 8PCHA 4Q8GA 3OVZA 4YYSA 3BCNA 1CVZA 3BPMA 3N3GA 1QXPA 1TU6A 3AI8A 4YYRA 3I3TA 2VFBA 2XU3A 3MHHA 1FH0A 1GLOA 4AXMA 1GECE 4N8WA 4C5PA 1F2AA 2PADA 4Q8HA 1YVBA 1M6DA 1PCIA 1NLJA 2CIOA 2ACTA 4WA6A 5A24A 1EWPA 2VFCA 2BDLA 2DJGB 4MZSA 2BDZA 1ZIVA 4FJCA 2C0YA 2Y5BA 3KWZA 2JQFR 1VJVA 3I06A 3LTWA 2OP3A 1MIRA 3M99A 1Q6KA 2WBFX 1PADA 4YYUA 3IHPA 2OZ2A 3OF8A 2FQ9A 2FUDA 1AYUA 2DCCA 1NB3A 3P5WA 4BS6A 1W5RA 1CV8A 2YJ8A 1F29A 4I07A 1EF7A 3KWBX 4NV8A 1DEUA 7PCKA 3E1ZB 1POPA 5CVOB 3WXEA 4N79A 5FPWA 1AECA 3IEJA 2ATOA 3C9EA 2HD5A 2R9MA 1KXRA 1PPOA 1Y4HA 1PBHA 4BS5A 3WXFA 4DMYA 9PAPA 1A6RA 3LXSA 4GUZA 3S3QA 3RVWA 1AU0A 3RVVA 2AYOA 2PBHA 3H8BA 4BQVA 1MEMA 5EF4A 2G8JA 3CBKA 1BQIA 1MHWA 1TLOA 1ME3A 1MS6A 5CHTA 1GCBA 2FO5A 1EWMA 2XU1A 2YJ2A 1IWDA 1QOLA 3KSEA 4PI3A 3HHAA 1KFUL 2FRQA 2NQAA 5PADA 2JQGR 3CBJA 3MTNA 2YJBA 2F7DA 1AIMA 1ITOA 4OEMA 4NV7A 3F5VA 1BGOA 2E00A 3KW9A 6PADA 2AS8A 4PP2E 2IBIA 4FK5A 3ZUAA 1CTEA 3OISA 2FRAA 3P5XA 1AYVA 5F02A 5JH3A 3OF9A 4MZOA 2R9OA 1GMYA 4BSQA 1XKGA 2XU5A 3TNXA 4PADA 4HWYA 1NB5A 4QRVA 4CDFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IUT A;  4W4U A;  4X6H A;  4YYW A;  3LFY A;  1CQD A;  4QRX A;  2G7Y A;  3P5V A;  3PNR A;  3HHI A;  3BOW A;  5CHV A;  1U5I A;  3H6S A;  2DZZ A;  1O0E A;  2R9C A;  2HHN A;  1THE A;  2YJ9 A;  3KKU A;  2NQI A;  3O0U A;  3B79 A;  2GFO A;  3WXG A;  4YV8 A;  3K8U A;  1BY8 A;  3CH2 X;  2P0R A;  2E03 A;  1PIP A;  4OEL A;  4X6J A;  3IMA A;  3BPF A;  1U9X A;  4CDE B;  4DMX A;  2O6X A;  1PPD A;  1AU3 A;  3U8E A;  1YT7 A;  2HXZ A;  3N3K A;  3ERV A;  1U9V A;  3BWK A;  4AXL A;  2VHS A;  5JA7 A;  3USV A;  4BPV A;  4K7C A;  2AYN A;  4PP1 A;  4I05 A;  3IV2 A;  4QRG A;  1CS8 A;  1NQC A;  2AVW A;  2CB5 A;  3O1G A;  4MSX A;  3BC3 A;  3H7D A;  1U9W A;  3OVX A;  4P6G A;  1EWL A;  2NQG A;  1VSN A;  2YJC A;  3K9M A;  3V6C A;  2F1G A;  3HD3 A;  4CDC B;  2B1N A;  3QSD A;  1ATK A;  1BP4 A;  1F2C A;  2P7U A;  2R9N A;  2AUZ A;  3H89 A;  1MDW A;  3K24 A;  1CPJ A;  1JQP A;  1PPP A;  2AU1 A;  2G6D A;  1AYW A;  1KFX L;  2R9F A;  3P5U A;  4I04 A;  2HH5 A;  2DC8 A;  2G8E A;  3V6E A;  1CSB B;  3PDF A;  4P6E A;  3D6S A;  3F75 A;  1SNK A;  2ARY A;  1SP4 B;  4KLB A;  1EWO A;  2DJF B;  1QMY A;  1S4V A;  2Y6E A;  3N4C A;  2DC7 A;  2E01 A;  1U9Q X;  5CVM A;  2FYE A;  2DC6 A;  1F2B A;  1HUC B;  3MHS A;  2GHU A;  4YYV A;  1K3B B;  1ZCM A;  3IOQ A;  3H8C A;  2DCB A;  4FIP A;  3QT4 A;  2FTD A;  4X6I A;  5K16 A;  1CJL A;  1YK7 A;  5EGW A;  5CVN B;  1YK8 A;  2H7J A;  3RVX A;  2DCA A;  4G54 A;  1NL6 A;  4YYQ A;  2DZY A;  5J94 A;  2VHF A;  3S3R A;  4W5B A;  1X9Y A;  2IPP B;  1AU4 A;  1STF E;  1PE6 A;  2FT2 A;  4N4Z A;  2OUL A;  3PBH A;  1ME4 A;  4XR7 A;  2P86 A;  2AIM A;  4CDD B;  1YAL A;  1ICF A;  2E02 A;  4QH6 A;  3CH3 X;  1PPN A;  2PNS A;  4YVA A;  1KHQ A;  2PRE A;  4XUI A;  2DCD A;  3DF0 A;  1KHP A;  4W5C A;  1MEG A;  1AU2 A;  1CB5 A;  3NHE A;  1Y08 A;  3GCB A;  1DF0 A;  3MOR A;  3QJ3 A;  2XU4 A;  3HWN A;  1QDQ A;  4CZW A;  4ZUX U;  2DC9 A;  1PXV A;  2B1M A;  4RY2 A;  2AUX A;  2NQD B;  3KX1 A;  1NPZ A;  3PW3 A;  2R6N A;  4QBB A;  3KFQ A;  1TL9 A;  8PCH A;  4Q8G A;  3OVZ A;  4YYS A;  3BCN A;  1CVZ A;  3BPM A;  3N3G A;  1QXP A;  1TU6 A;  3AI8 A;  4YYR A;  3I3T A;  2XU3 A;  3MHH A;  1FH0 A;  1GLO A;  4AXM A;  1GEC E;  4N8W A;  1F2A A;  2PAD A;  4Q8H A;  1YVB A;  1M6D A;  1PCI A;  1NLJ A;  2CIO A;  2ACT A;  4WA6 A;  5A24 A;  1EWP A;  2BDL A;  2DJG B;  4MZS A;  2BDZ A;  1ZIV A;  4FJC A;  2C0Y A;  2Y5B A;  3KWZ A;  2JQF R;  1VJV A;  3I06 A;  2OP3 A;  1MIR A;  3M99 A;  1Q6K A;  2WBF X;  1PAD A;  4YYU A;  3IHP A;  2OZ2 A;  3OF8 A;  2FQ9 A;  2FUD A;  1AYU A;  2DCC A;  1NB3 A;  3P5W A;  4BS6 A;  1CV8 A;  2YJ8 A;  1F29 A;  4I07 A;  1EF7 A;  3KWB X;  1DEU A;  7PCK A;  3E1Z B;  1POP A;  5CVO B;  3WXE A;  4N79 A;  5FPW A;  1AEC A;  3IEJ A;  2ATO A;  3C9E A;  2HD5 A;  2R9M A;  1KXR A;  1PPO A;  1Y4H A;  1PBH A;  4BS5 A;  3WXF A;  4DMY A;  9PAP A;  1A6R A;  3LXS A;  3S3Q A;  3RVW A;  1AU0 A;  3RVV A;  2AYO A;  2PBH A;  3H8B A;  4BQV A;  1MEM A;  5EF4 A;  2G8J A;  3CBK A;  1BQI A;  1MHW A;  1TLO A;  1ME3 A;  1MS6 A;  5CHT A;  1GCB A;  2FO5 A;  1EWM A;  2XU1 A;  2YJ2 A;  1IWD A;  1QOL A;  3KSE A;  4PI3 A;  3HHA A;  1KFU L;  2FRQ A;  2NQA A;  5PAD A;  2JQG R;  3CBJ A;  3MTN A;  2YJB A;  2F7D A;  1AIM A;  1ITO A;  4OEM A;  3F5V A;  1BGO A;  2E00 A;  3KW9 A;  6PAD A;  2AS8 A;  4PP2 E;  2IBI A;  4FK5 A;  3ZUA A;  1CTE A;  3OIS A;  2FRA A;  3P5X A;  1AYV A;  5F02 A;  5JH3 A;  3OF9 A;  4MZO A;  2R9O A;  1GMY A;  4BSQ A;  1XKG A;  2XU5 A;  3TNX A;  4PAD A;  4HWY A;  1NB5 A;  4QRV A;  4CDF B; 
#chains in the Genus database with same CATH topology
 3IUT A;  4W4U A;  3PT2 A;  4X6H A;  4YYW A;  1YZB A;  3LFY A;  1CQD A;  4D8E A;  4QRX A;  2G7Y A;  3P5V A;  3PNR A;  3HHI A;  3BOW A;  5CHV A;  1U5I A;  3H6S A;  2DZZ A;  1O0E A;  2R9C A;  4HXD B;  2HHN A;  1THE A;  3C0R A;  4MM3 B;  2YJ9 A;  3KKU A;  2NQI A;  3O0U A;  3B79 A;  2GFO A;  4IUM A;  3OQC A;  4REZ A;  3WXG A;  3ZNH A;  4M0W A;  4YV8 A;  3K8U A;  3MP2 A;  1BY8 A;  3CH2 X;  2P0R A;  2E03 A;  1PIP A;  4OEL A;  4OVZ A;  4X6J A;  3IMA A;  3BPF A;  1U9X A;  4CDE B;  4DMX A;  2O6X A;  1PPD A;  1AU3 A;  3U8E A;  1YT7 A;  2HXZ A;  3N3K A;  3PRM A;  3ERV A;  1U9V A;  4PT5 A;  3BWK A;  4AXL A;  4RF0 A;  2VHS A;  5JA7 A;  3USV A;  4BPV A;  4K7C A;  2AYN A;  4PP1 A;  2JRI A;  4I05 A;  3IV2 A;  1PVJ A;  4QRG A;  1CS8 A;  1NQC A;  2AVW A;  2CB5 A;  3O1G A;  4MSX A;  3BC3 A;  3PSE A;  3H7D A;  1U9W A;  4R3D A;  3OVX A;  4P6G A;  2J7Q C;  1EWL A;  2NQG A;  1VSN A;  2J7Q A;  2YJC A;  3K9M A;  4D8B A;  3V6C A;  2F1G A;  2BTW A;  3HD3 A;  4CDC B;  2B1N A;  3QSD A;  1ATK A;  1BP4 A;  1F2C A;  2P7U A;  2R9N A;  4MI7 A;  2AUZ A;  3H89 A;  1MDW A;  3K24 A;  1CPJ A;  3RNV A;  1JQP A;  1PPP A;  2AU1 A;  2G6D A;  1AYW A;  1KFX L;  2R9F A;  4BOS A;  3TMP A;  3P5U A;  4I04 A;  2HH5 A;  4GUA A;  4OVZ B;  2DC8 A;  2G8E A;  3V6E A;  1CSB B;  3PDF A;  4P6E A;  3D6S A;  3F75 A;  1SNK A;  4XZX A;  2ARY A;  1SP4 B;  4KLB A;  1EWO A;  2DJF B;  5EZS A;  1QMY A;  1S4V A;  2Y6E A;  3N4C A;  2DC7 A;  4P16 A;  2E01 A;  1U9Q X;  5CVM A;  2FYE A;  4BOQ A;  2DC6 A;  1F2B A;  1HUC B;  3MJ5 A;  3MHS A;  2GHU A;  4YYV A;  4RKX A;  1K3B B;  1ZCM A;  3IOQ A;  3H8C A;  2DCB A;  4FIP A;  3QT4 A;  2FTD A;  4X6I A;  4BOP A;  5K16 A;  1CJL A;  4A5U A;  1YK7 A;  5EGW A;  5CVN B;  1YK8 A;  2H7J A;  3RVX A;  2DCA A;  4G54 A;  3W31 A;  1NL6 A;  4YYQ A;  1DKI A;  2DZY A;  5J94 A;  2VHF A;  2AGA A;  2BTW B;  3S3R A;  4W5B A;  1X9Y A;  2IPP B;  3PHX A;  4WUR A;  1AU4 A;  1STF E;  1PE6 A;  5KO3 A;  2FT2 A;  4N4Z A;  2OUL A;  3PBH A;  1ME4 A;  4OW0 A;  4XR7 A;  2P86 A;  2AIM A;  4CDD B;  1YAL A;  1ICF A;  2E02 A;  4QH6 A;  3CH3 X;  1PPN A;  2PNS A;  3BB7 A;  4YVA A;  1KHQ A;  2PRE A;  4XUI A;  2DCD A;  3DF0 A;  1KHP A;  4W5C A;  1MEG A;  1AU2 A;  1CB5 A;  4BOU A;  3NHE A;  3E9S A;  1Y08 A;  3GCB A;  3PHU A;  1DF0 A;  3MOR A;  3QJ3 A;  2XU4 A;  3HWN A;  1QDQ A;  4CZW A;  4ZUX U;  2DC9 A;  1PXV A;  2B1M A;  4RY2 A;  2AUX A;  2NQD B;  3KX1 A;  1NPZ A;  3W30 A;  2UZJ A;  3PW3 A;  2DOS A;  2R6N A;  4QBB A;  3KFQ A;  1TL9 A;  8PCH A;  4Q8G A;  3OVZ A;  4YYS A;  3BCN A;  1CVZ A;  3BPM A;  3MTV A;  3N3G A;  1QXP A;  1TU6 A;  3AI8 A;  4YYR A;  3I3T A;  2XU3 A;  2JTC A;  3MHH A;  1FH0 A;  1GLO A;  4AXM A;  1GEC E;  4N8W A;  1F2A A;  2PAD A;  4Q8H A;  1YVB A;  1M6D A;  1PCI A;  1NLJ A;  2FE8 A;  2CIO A;  1UKF A;  2ACT A;  3IFU A;  4WA6 A;  5A24 A;  1EWP A;  2BDL A;  5EZQ A;  2DJG B;  4MZS A;  3PHW A;  2BDZ A;  1ZIV A;  4FJC A;  2C0Y A;  2Y5B A;  3KWZ A;  2JQF R;  1VJV A;  3I06 A;  2OP3 A;  4IP3 A;  1MIR A;  3BBA A;  3M99 A;  1Q6K A;  2WBF X;  2BU3 A;  1PAD A;  4YYU A;  3IHP A;  2OZ2 A;  3OF8 A;  2FQ9 A;  3TRK A;  2FUD A;  1AYU A;  2DCC A;  1NB3 A;  3P5W A;  4BS6 A;  1CV8 A;  2YJ8 A;  1F29 A;  4I07 A;  1EF7 A;  4RF1 A;  3KWB X;  4ZTB A;  1DEU A;  7PCK A;  3E1Z B;  1POP A;  5CVO B;  3WXE A;  5E6J A;  4N79 A;  5FPW A;  1AEC A;  3IEJ A;  2ATO A;  3BY4 A;  3C9E A;  2HD5 A;  3B21 A;  2R9M A;  1KXR A;  1PPO A;  1Y4H A;  1PBH A;  4BS5 A;  3WXF A;  4DMY A;  9PAP A;  1A6R A;  3LXS A;  2Z84 A;  3S3Q A;  3RVW A;  1AU0 A;  3RVV A;  2AYO A;  2PBH A;  2HWK A;  3H8B A;  4BQV A;  1MEM A;  5EF4 A;  2G8J A;  3CBK A;  1BQI A;  1MHW A;  1TLO A;  1ME3 A;  1MS6 A;  5CHT A;  1GCB A;  2FO5 A;  1EWM A;  2XU1 A;  2YJ2 A;  1IWD A;  1QOL A;  3KSE A;  4PI3 A;  3HHA A;  4BOZ A;  1KFU L;  3O65 A;  2FRQ A;  2NQA A;  5PAD A;  2JQG R;  3CBJ A;  3MTN A;  2YJB A;  2F7D A;  1AIM A;  1ITO A;  4OEM A;  3F5V A;  1BGO A;  2E00 A;  3PRP A;  3KW9 A;  6PAD A;  4RNA A;  2AS8 A;  4PP2 E;  2IBI A;  4FK5 A;  3ZUA A;  1CTE A;  3OIS A;  4D8I A;  2FRA A;  3P5X A;  1AYV A;  5F02 A;  5JH3 A;  3OF9 A;  5JZE A;  4MZO A;  2R9O A;  1GMY A;  4BSQ A;  1XKG A;  2XU5 A;  3TNX A;  4PAD A;  4HWY A;  1NB5 A;  4QRV A;  4CDF B; 
#chains in the Genus database with same CATH homology
 3IUT A;  4W4U A;  4X6H A;  4YYW A;  3LFY A;  1CQD A;  4QRX A;  2G7Y A;  3P5V A;  3PNR A;  3HHI A;  3BOW A;  5CHV A;  1U5I A;  3H6S A;  2DZZ A;  1O0E A;  2R9C A;  2HHN A;  1THE A;  2YJ9 A;  3KKU A;  2NQI A;  3O0U A;  3B79 A;  2GFO A;  3WXG A;  4YV8 A;  3K8U A;  1BY8 A;  3CH2 X;  2P0R A;  2E03 A;  1PIP A;  4OEL A;  4X6J A;  3IMA A;  3BPF A;  1U9X A;  1W4T A;  4CDE B;  4DMX A;  2O6X A;  1PPD A;  1AU3 A;  3U8E A;  1YT7 A;  2HXZ A;  3N3K A;  3ERV A;  1U9V A;  3BWK A;  4AXL A;  2VHS A;  5JA7 A;  3USV A;  4BPV A;  4K7C A;  2AYN A;  4PP1 A;  4I05 A;  3IV2 A;  4QRG A;  1CS8 A;  1NQC A;  2AVW A;  2CB5 A;  3O1G A;  4MSX A;  3BC3 A;  3H7D A;  1U9W A;  3OVX A;  4P6G A;  1EWL A;  2NQG A;  1VSN A;  2YJC A;  3K9M A;  3V6C A;  2F1G A;  3HD3 A;  4CDC B;  2B1N A;  3QSD A;  1ATK A;  1BP4 A;  1F2C A;  2P7U A;  2R9N A;  2AUZ A;  3H89 A;  1MDW A;  3K24 A;  1CPJ A;  1JQP A;  1PPP A;  2AU1 A;  2G6D A;  1AYW A;  1KFX L;  2R9F A;  4B55 A;  1GX3 A;  3P5U A;  4I04 A;  2HH5 A;  2DC8 A;  2G8E A;  3V6E A;  1CSB B;  3PDF A;  4P6E A;  3D6S A;  3F75 A;  1SNK A;  2ARY A;  1SP4 B;  4KLB A;  1EWO A;  2DJF B;  1QMY A;  1S4V A;  2Y6E A;  3N4C A;  2DC7 A;  2E01 A;  1U9Q X;  5CVM A;  2FYE A;  2DC6 A;  1F2B A;  1HUC B;  3MHS A;  2GHU A;  4YYV A;  1E2T A;  4BGF A;  1K3B B;  1ZCM A;  3IOQ A;  3H8C A;  2DCB A;  4FIP A;  3QT4 A;  2FTD A;  4X6I A;  5K16 A;  1CJL A;  1YK7 A;  5EGW A;  5CVN B;  1YK8 A;  2H7J A;  3RVX A;  2DCA A;  4G54 A;  1NL6 A;  4YYQ A;  2BSZ A;  2DZY A;  5J94 A;  2VHF A;  3S3R A;  4W5B A;  1X9Y A;  2IPP B;  1AU4 A;  1STF E;  1PE6 A;  2FT2 A;  4N4Z A;  2OUL A;  3PBH A;  1ME4 A;  4XR7 A;  2P86 A;  2AIM A;  4CDD B;  1YAL A;  1ICF A;  2E02 A;  4QH6 A;  3CH3 X;  1PPN A;  2PNS A;  4YVA A;  1KHQ A;  2PRE A;  4XUI A;  2DCD A;  3DF0 A;  1KHP A;  4W5C A;  1MEG A;  1AU2 A;  1CB5 A;  3NHE A;  1W6F A;  1Y08 A;  3GCB A;  1DF0 A;  3MOR A;  3QJ3 A;  2XU4 A;  3HWN A;  1QDQ A;  4CZW A;  4ZUX U;  2DC9 A;  1PXV A;  2B1M A;  4RY2 A;  2AUX A;  2NQD B;  3KX1 A;  1NPZ A;  3D9W A;  3PW3 A;  2R6N A;  4QBB A;  3KFQ A;  1TL9 A;  8PCH A;  4Q8G A;  3OVZ A;  4YYS A;  3BCN A;  1CVZ A;  3BPM A;  3N3G A;  1QXP A;  1TU6 A;  3AI8 A;  4YYR A;  3I3T A;  2VFB A;  2XU3 A;  3MHH A;  1FH0 A;  1GLO A;  4AXM A;  1GEC E;  4N8W A;  4C5P A;  1F2A A;  2PAD A;  4Q8H A;  1YVB A;  1M6D A;  1PCI A;  1NLJ A;  2CIO A;  2ACT A;  4WA6 A;  5A24 A;  1EWP A;  2VFC A;  2BDL A;  2DJG B;  4MZS A;  2BDZ A;  1ZIV A;  4FJC A;  2C0Y A;  2Y5B A;  3KWZ A;  2JQF R;  1VJV A;  3I06 A;  3LTW A;  2OP3 A;  1MIR A;  3M99 A;  1Q6K A;  2WBF X;  1PAD A;  4YYU A;  3IHP A;  2OZ2 A;  3OF8 A;  2FQ9 A;  2FUD A;  1AYU A;  2DCC A;  1NB3 A;  3P5W A;  4BS6 A;  1W5R A;  1CV8 A;  2YJ8 A;  1F29 A;  4I07 A;  1EF7 A;  3KWB X;  4NV8 A;  1DEU A;  7PCK A;  3E1Z B;  1POP A;  5CVO B;  3WXE A;  4N79 A;  5FPW A;  1AEC A;  3IEJ A;  2ATO A;  3C9E A;  2HD5 A;  2R9M A;  1KXR A;  1PPO A;  1Y4H A;  1PBH A;  4BS5 A;  3WXF A;  4DMY A;  9PAP A;  1A6R A;  3LXS A;  4GUZ A;  3S3Q A;  3RVW A;  1AU0 A;  3RVV A;  2AYO A;  2PBH A;  3H8B A;  4BQV A;  1MEM A;  5EF4 A;  2G8J A;  3CBK A;  1BQI A;  1MHW A;  1TLO A;  1ME3 A;  1MS6 A;  5CHT A;  1GCB A;  2FO5 A;  1EWM A;  2XU1 A;  2YJ2 A;  1IWD A;  1QOL A;  3KSE A;  4PI3 A;  3HHA A;  1KFU L;  2FRQ A;  2NQA A;  5PAD A;  2JQG R;  3CBJ A;  3MTN A;  2YJB A;  2F7D A;  1AIM A;  1ITO A;  4OEM A;  4NV7 A;  3F5V A;  1BGO A;  2E00 A;  3KW9 A;  6PAD A;  2AS8 A;  4PP2 E;  2IBI A;  4FK5 A;  3ZUA A;  1CTE A;  3OIS A;  2FRA A;  3P5X A;  1AYV A;  5F02 A;  5JH3 A;  3OF9 A;  4MZO A;  2R9O A;  1GMY A;  4BSQ A;  1XKG A;  2XU5 A;  3TNX A;  4PAD A;  4HWY A;  1NB5 A;  4QRV A;  4CDF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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