2NQDB

Crystal structure of cysteine protease inhibitor, chagasin, in complex with human cathepsin l
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
221
structure length
221
Chain Sequence
EAPRSVDWREKGYVTPVKNQGQCGSAWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease
pubmed doi rcsb
molecule tags Hydrolase inhibitor/hydrolase
source organism Trypanosoma cruzi
molecule keywords Chagasin
total genus 72
structure length 221
sequence length 221
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2nqdB00
1S4VA 1YVBA 4YVAA 4YV8A 1ME4A 1YK7A 2DCBA 4DMXA 4XUIA 5EF4A 3F75A 2AUZA 2Y6EA 3DF0A 2AIMA 3MORA 1MEMA 3KKUA 3RVWA 1EWOA 2IBIA 4BPVA 2YJ2A 2XU4A 3NHEA 1XKGA 3K9MA 2YJBA 1KFXL 4N8WA 4BS6A 2JQGR 1Q6KA 3P5UA 4YYRA 2ACTA 3QT4A 1EF7A 1U9QX 4YYWA 3KSEA 1F29A 1PPOA 2GHUA 2FRAA 5K16A 3HHAA 3V6CA 1AU3A 2DJFB 3C9EA 2HXZA 4W5CA 5PADA 2E00A 4QH6A 1PPNA 5FPWA 3BOWA 3CH2X 1BP4A 1ICFA 3LXSA 1CVZA 1DF0A 3OISA 2G8JA 4DMYA 2DC9A 1DEUA 3TNXA 1SNKA 1CSBB 4OELA 2R9FA 3N3KA 2HD5A 2GFOA 3LFYA 2PREA 2DZYA 1U9WA 4FK5A 1EWPA 4ZUXU 3GCBA 3OF8A 1VJVA 1PIPA 3H8CA 5F02A 1Y08A 2R9OA 4BSQA 3IV2A 5CVNB 1MIRA 3N3GA 4RY2A 3MTNA 2E02A 1BQIA 3H8BA 3M99A 1AYVA 2CIOA 2F7DA 1PPDA 1O0EA 5JH3A 3ZUAA 1ATKA 3O0UA 5CHTA 4MSXA 3USVA 4QRVA 2Y5BA 4CZWA 1ITOA 1Y4HA 1NL6A 4X6IA 3N4CA 1THEA 1KXRA 2JQFR 2PNSA 1MS6A 4BS5A 1GLOA 4I04A 3KX1A 2B1NA 2G8EA 2E01A 3BPFA 4I05A 4QBBA 3H89A 3MHHA 2AU1A 2FUDA 2AYNA 1STFE 2DC7A 2NQAA 2AVWA 3MHSA 4MZSA 1AIMA 4FIPA 3QJ3A 2G7YA 1TLOA 2VHFA 4YYQA 2XU5A 4CDCB 3U8EA 3BCNA 1EWLA 2H7JA 1U9XA 1ZCMA 8PCHA 3WXEA 3PW3A 1PADA 3B79A 1K3BB 4CDDB 3PBHA 4KLBA 1QOLA 1CS8A 1PE6A 2P86A 1A6RA 2BDZA 3ERVA 4YYVA 1PPPA 3QSDA 1TU6A 1U5IA 1MHWA 6PADA 2YJ9A 3I06A 4G54A 1PCIA 4Q8HA 4YYUA 1NB5A 3KFQA 3PNRA 2C0YA 3IMAA 2OP3A 3OF9A 3P5XA 7PCKA 3OVZA 2P7UA 2R9CA 5EGWA 2PBHA 2PADA 1BGOA 1KFUL 2YJ8A 2FTDA 2AUXA 1F2CA 1EWMA 3IEJA 5CVOB 3RVXA 3CBJA 3E1ZB 3BPMA 2G6DA 4Q8GA 2R9NA 1F2BA 1TL9A 1YT7A 1ME3A 2WBFX 2NQGA 1GECE 3O1GA 4QRXA 4CDEB 2HHNA 1AECA 4AXLA 2FQ9A 1GCBA 4YYSA 1PBHA 5JA7A 4K7CA 2E03A 1CJLA 4PADA 3WXFA 3CBKA 1NLJA 1VSNA 2VHSA 4N4ZA 4WA6A 4N79A 4P6EA 3D6SA 1CV8A 1AU0A 1ZIVA 1YALA 4OEMA 5CVMA 2YJCA 3WXGA 3PDFA 3KWZA 1QMYA 1FH0A 4W5BA 1KHQA 1CPJA 1HUCB 1AU2A 1IWDA 4P6GA 2CB5A 1X9YA 2P0RA 2OULA 2DJGB 4AXMA 1BY8A 2O6XA 3IHPA 1JQPA 3AI8A 1PXVA 3KW9A 3H7DA 3K8UA 1KHPA 2AS8A 2BDLA 3KWBX 1NB3A 2DC6A 2AYOA 1M6DA 4MZOA 4HWYA 2XU1A 2DCAA 1SP4B 3I3TA 1CTEA 1CB5A 5CHVA 2DZZA 4I07A 2DCDA 4W4UA 3P5WA 2DC8A 3RVVA 4BQVA 2FO5A 3S3QA 1GMYA 2FYEA 3OVXA 1POPA 1AYWA 1NQCA 1YK8A 2HH5A 4X6HA 4QRGA 2B1MA 3F5VA 2FRQA 3BWKA 2NQDB 4CDFB 4PI3A 3H6SA 3HWNA 9PAPA 2FT2A 3HHIA 5J94A 2ARYA 2R6NA 4PP1A 2R9MA 1F2AA 2ATOA 2DCCA 3HD3A 3IOQA 1MDWA 1QXPA 4XR7A 4PP2E 3S3RA 2NQIA 1AYUA 2F1GA 4FJCA 3P5VA 3K24A 1U9VA 1AU4A 1QDQA 1NPZA 5A24A 2XU3A 3V6EA 3IUTA 2OZ2A 1MEGA 2IPPB 3BC3A 1CQDA 4X6JA 3CH3X
chains in the Genus database with same CATH superfamily
1S4VA 4M0WA 1YVBA 1UKFA 4YVAA 3PRPA 4YV8A 1ME4A 1YK7A 2DCBA 4DMXA 4XUIA 5EF4A 3F75A 2AUZA 2Y6EA 3DF0A 4PT5A 3MTVA 2AIMA 3MORA 1MEMA 3KKUA 3RVWA 1EWOA 2IBIA 4BPVA 3B21A 2YJ2A 2XU4A 3NHEA 1XKGA 3K9MA 2YJBA 1KFXL 4N8WA 2BU3A 4BS6A 2JQGR 1Q6KA 3P5UA 3E9SA 4YYRA 2ACTA 3QT4A 1EF7A 1U9QX 2AGAA 4YYWA 3KSEA 1F29A 1PPOA 2GHUA 2FRAA 5K16A 4RKXA 3HHAA 3V6CA 1AU3A 2DJFB 3C9EA 5EZQA 2HXZA 4W5CA 5PADA 2E00A 4QH6A 1PPNA 5FPWA 3BOWA 2HWKA 3CH2X 1BP4A 1ICFA 3LXSA 1CVZA 1DF0A 3OISA 2G8JA 3W30A 4DMYA 2DC9A 1DKIA 1DEUA 4RNAA 3TNXA 1SNKA 2UZJA 1CSBB 4OELA 5KO3A 2R9FA 3N3KA 2HD5A 2GFOA 3LFYA 2PREA 2DZYA 1U9WA 4FK5A 1EWPA 4ZUXU 4BOQA 3GCBA 3W31A 3OF8A 1VJVA 1PIPA 2FE8A 3H8CA 5F02A 1Y08A 2R9OA 4OVZA 4BSQA 3IV2A 5CVNB 1MIRA 3N3GA 4RY2A 3MTNA 2E02A 4RF1A 1BQIA 3H8BA 3M99A 3BY4A 1AYVA 2CIOA 5JZEA 2F7DA 1PPDA 4OVZB 1O0EA 5JH3A 4MM3B 3OQCA 3ZUAA 4D8IA 1ATKA 3O0UA 5CHTA 3RNVA 4MSXA 3USVA 4QRVA 2Y5BA 4CZWA 1ITOA 1Y4HA 1NL6A 4X6IA 3N4CA 1THEA 1KXRA 2JQFR 2PNSA 1MS6A 4BS5A 1GLOA 4I04A 3KX1A 2B1NA 2G8EA 2E01A 3BPFA 4I05A 4QBBA 3H89A 3MHHA 2AU1A 2FUDA 2AYNA 1STFE 2DC7A 2DOSA 2NQAA 2AVWA 3MHSA 4MI7A 4MZSA 1AIMA 4FIPA 1PVJA 1YZBA 3QJ3A 2G7YA 2JTCA 1TLOA 2VHFA 4YYQA 2XU5A 4CDCB 3U8EA 3BCNA 1EWLA 2H7JA 1U9XA 1ZCMA 8PCHA 3WXEA 3PW3A 1PADA 3B79A 1K3BB 2J7QA 4CDDB 3PBHA 4KLBA 1QOLA 3BB7A 1CS8A 1PE6A 2P86A 1A6RA 2BDZA 3ERVA 4YYVA 1PPPA 3QSDA 3PT2A 1TU6A 1U5IA 1MHWA 6PADA 2YJ9A 3I06A 4G54A 1PCIA 4Q8HA 4YYUA 1NB5A 3KFQA 3MP2A 3PNRA 2C0YA 3PHXA 4BOZA 2BTWA 3IMAA 4IP3A 2OP3A 3OF9A 3P5XA 3PHUA 7PCKA 3OVZA 2P7UA 2R9CA 5EGWA 2PBHA 2PADA 1BGOA 1KFUL 2YJ8A 5EZSA 2FTDA 2AUXA 3O65A 1F2CA 1EWMA 3IEJA 5CVOB 4OW0A 3RVXA 3CBJA 2JRIA 3E1ZB 3BPMA 2G6DA 4Q8GA 2R9NA 1F2BA 1TL9A 1YT7A 1ME3A 2WBFX 2NQGA 2Z84A 1GECE 3O1GA 4QRXA 4CDEB 2HHNA 1AECA 4AXLA 2FQ9A 1GCBA 4YYSA 1PBHA 5JA7A 4K7CA 2E03A 1CJLA 4PADA 3WXFA 3CBKA 1NLJA 4BOSA 1VSNA 2VHSA 4N4ZA 4WA6A 4N79A 3PRMA 4REZA 4P6EA 3D6SA 4IUMA 1CV8A 1AU0A 1ZIVA 1YALA 4OEMA 5CVMA 2YJCA 3WXGA 3PDFA 3KWZA 3TRKA 1QMYA 1FH0A 4W5BA 4D8EA 1KHQA 1CPJA 1HUCB 1AU2A 1IWDA 2CB5A 3PHWA 4P6GA 1X9YA 3ZNHA 4BOPA 2P0RA 2OULA 2DJGB 4AXMA 5E6JA 1BY8A 4WURA 2O6XA 3IHPA 1JQPA 3AI8A 1PXVA 3KW9A 3H7DA 3K8UA 1KHPA 2AS8A 2BDLA 3KWBX 1NB3A 2DC6A 2AYOA 1M6DA 4MZOA 4HWYA 2XU1A 2DCAA 4D8BA 4GUAA 1SP4B 2J7QC 3I3TA 1CTEA 1CB5A 4A5UA 4R3DA 5CHVA 2DZZA 4I07A 2DCDA 4W4UA 3P5WA 3PSEA 2DC8A 3RVVA 4BQVA 4XZXA 2FO5A 3S3QA 1GMYA 3BBAA 2FYEA 3OVXA 1POPA 1AYWA 3MJ5A 1NQCA 3IFUA 1YK8A 2HH5A 4X6HA 2BTWB 4RF0A 4QRGA 2B1MA 3F5VA 2FRQA 3BWKA 4P16A 2NQDB 4CDFB 4PI3A 3H6SA 3HWNA 9PAPA 2FT2A 3HHIA 5J94A 3TMPA 2ARYA 2R6NA 4PP1A 4HXDB 2R9MA 4ZTBA 1F2AA 2ATOA 2DCCA 3HD3A 3IOQA 1MDWA 1QXPA 4XR7A 4PP2E 3S3RA 2NQIA 1AYUA 2F1GA 4FJCA 3P5VA 3K24A 1U9VA 1AU4A 1QDQA 1NPZA 5A24A 2XU3A 3C0RA 3V6EA 3IUTA 2OZ2A 1MEGA 2IPPB 3BC3A 1CQDA 4BOUA 4X6JA 3CH3X
chains in the Genus database with same CATH topology
1S4VA 1YVBA 4NV7A 4YVAA 4YV8A 1ME4A 1YK7A 2DCBA 4DMXA 4XUIA 5EF4A 3F75A 2AUZA 2Y6EA 3DF0A 4BGFA 2AIMA 3MORA 1MEMA 3KKUA 3RVWA 1EWOA 2IBIA 4BPVA 1W4TA 2YJ2A 2XU4A 3NHEA 1XKGA 3K9MA 2YJBA 1KFXL 4N8WA 4BS6A 2JQGR 1Q6KA 3P5UA 4YYRA 2ACTA 3QT4A 1EF7A 1U9QX 4YYWA 3KSEA 1F29A 1PPOA 2GHUA 2FRAA 5K16A 3HHAA 3V6CA 1AU3A 2DJFB 3C9EA 2HXZA 4W5CA 5PADA 2E00A 4QH6A 1PPNA 5FPWA 3BOWA 3CH2X 1BP4A 1ICFA 3LXSA 1CVZA 1DF0A 3OISA 2G8JA 4DMYA 2DC9A 1DEUA 3TNXA 1SNKA 1CSBB 4OELA 2R9FA 3N3KA 2HD5A 2GFOA 3LFYA 2PREA 2DZYA 1U9WA 4FK5A 1EWPA 4ZUXU 3GCBA 3D9WA 3OF8A 1VJVA 1PIPA 3H8CA 5F02A 1Y08A 2VFCA 2R9OA 4BSQA 3IV2A 5CVNB 1MIRA 3N3GA 4RY2A 3MTNA 2E02A 1BQIA 4C5PA 3H8BA 3M99A 1AYVA 2CIOA 2F7DA 1PPDA 1O0EA 5JH3A 3ZUAA 1ATKA 3O0UA 5CHTA 4MSXA 3USVA 4QRVA 1W5RA 2Y5BA 4CZWA 1ITOA 1Y4HA 1NL6A 4X6IA 3N4CA 1THEA 1KXRA 2JQFR 2PNSA 1MS6A 4BS5A 1GLOA 4I04A 3KX1A 2B1NA 2G8EA 2E01A 3BPFA 1E2TA 4I05A 4QBBA 3H89A 3MHHA 2AU1A 2FUDA 2AYNA 1STFE 2DC7A 2NQAA 2AVWA 3MHSA 4MZSA 1AIMA 4FIPA 3QJ3A 2G7YA 1TLOA 2VHFA 4YYQA 2XU5A 4CDCB 3U8EA 3BCNA 1EWLA 2H7JA 1U9XA 1ZCMA 8PCHA 3WXEA 3PW3A 1PADA 3B79A 1K3BB 4CDDB 3PBHA 4KLBA 1QOLA 1CS8A 1PE6A 2P86A 1A6RA 2BDZA 3ERVA 4YYVA 1PPPA 3QSDA 1TU6A 1U5IA 1MHWA 6PADA 2YJ9A 3I06A 4G54A 1PCIA 4Q8HA 4YYUA 1NB5A 3KFQA 3PNRA 2C0YA 3IMAA 2OP3A 3OF9A 3P5XA 7PCKA 3OVZA 2P7UA 2R9CA 5EGWA 2PBHA 2PADA 1BGOA 1KFUL 2YJ8A 2FTDA 2AUXA 1F2CA 1EWMA 3IEJA 5CVOB 3RVXA 3CBJA 3E1ZB 3BPMA 2G6DA 4Q8GA 2R9NA 1F2BA 1TL9A 2VFBA 1YT7A 1ME3A 2WBFX 2NQGA 1GECE 3O1GA 4QRXA 4CDEB 2HHNA 1AECA 4AXLA 2FQ9A 1GCBA 4YYSA 1PBHA 5JA7A 4K7CA 2E03A 1CJLA 4PADA 3WXFA 3CBKA 1NLJA 1W6FA 1VSNA 2VHSA 4N4ZA 4WA6A 4N79A 4P6EA 3D6SA 1CV8A 1AU0A 1ZIVA 1YALA 4OEMA 5CVMA 2YJCA 3WXGA 3PDFA 3KWZA 1QMYA 1FH0A 4W5BA 1KHQA 1CPJA 1HUCB 1AU2A 1IWDA 2CB5A 4P6GA 1X9YA 2P0RA 2OULA 2DJGB 4AXMA 1BY8A 2O6XA 3IHPA 1JQPA 3AI8A 1PXVA 3KW9A 3H7DA 3K8UA 1KHPA 2AS8A 2BDLA 3KWBX 1NB3A 2DC6A 2AYOA 1M6DA 4MZOA 4HWYA 2XU1A 2DCAA 1SP4B 3LTWA 3I3TA 1CTEA 1CB5A 5CHVA 2DZZA 4I07A 2DCDA 4W4UA 3P5WA 2DC8A 3RVVA 4BQVA 2FO5A 3S3QA 1GMYA 2FYEA 3OVXA 1POPA 1AYWA 1NQCA 2BSZA 1YK8A 2HH5A 4X6HA 4QRGA 2B1MA 3F5VA 2FRQA 3BWKA 2NQDB 4CDFB 4PI3A 3H6SA 3HWNA 9PAPA 2FT2A 3HHIA 5J94A 2ARYA 2R6NA 4PP1A 4B55A 2R9MA 4GUZA 1F2AA 2ATOA 2DCCA 3HD3A 3IOQA 1MDWA 1QXPA 4XR7A 4NV8A 4PP2E 3S3RA 2NQIA 1AYUA 2F1GA 4FJCA 3P5VA 3K24A 1U9VA 1AU4A 1GX3A 1QDQA 1NPZA 5A24A 2XU3A 3V6EA 3IUTA 2OZ2A 1MEGA 2IPPB 3BC3A 1CQDA 4X6JA 3CH3X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1S4V A;  1YVB A;  4YVA A;  4YV8 A;  1ME4 A;  1YK7 A;  2DCB A;  4DMX A;  4XUI A;  5EF4 A;  3F75 A;  2AUZ A;  2Y6E A;  3DF0 A;  2AIM A;  3MOR A;  1MEM A;  3KKU A;  3RVW A;  1EWO A;  2IBI A;  4BPV A;  2YJ2 A;  2XU4 A;  3NHE A;  1XKG A;  3K9M A;  2YJB A;  1KFX L;  4N8W A;  4BS6 A;  2JQG R;  1Q6K A;  3P5U A;  4YYR A;  2ACT A;  3QT4 A;  1EF7 A;  1U9Q X;  4YYW A;  3KSE A;  1F29 A;  1PPO A;  2GHU A;  2FRA A;  5K16 A;  3HHA A;  3V6C A;  1AU3 A;  2DJF B;  3C9E A;  2HXZ A;  4W5C A;  5PAD A;  2E00 A;  4QH6 A;  1PPN A;  5FPW A;  3BOW A;  3CH2 X;  1BP4 A;  1ICF A;  3LXS A;  1CVZ A;  1DF0 A;  3OIS A;  2G8J A;  4DMY A;  2DC9 A;  1DEU A;  3TNX A;  1SNK A;  1CSB B;  4OEL A;  2R9F A;  3N3K A;  2HD5 A;  2GFO A;  3LFY A;  2PRE A;  2DZY A;  1U9W A;  4FK5 A;  1EWP A;  4ZUX U;  3GCB A;  3OF8 A;  1VJV A;  1PIP A;  3H8C A;  5F02 A;  1Y08 A;  2R9O A;  4BSQ A;  3IV2 A;  5CVN B;  1MIR A;  3N3G A;  4RY2 A;  3MTN A;  2E02 A;  1BQI A;  3H8B A;  3M99 A;  1AYV A;  2CIO A;  2F7D A;  1PPD A;  1O0E A;  5JH3 A;  3ZUA A;  1ATK A;  3O0U A;  5CHT A;  4MSX A;  3USV A;  4QRV A;  2Y5B A;  4CZW A;  1ITO A;  1Y4H A;  1NL6 A;  4X6I A;  3N4C A;  1THE A;  1KXR A;  2JQF R;  2PNS A;  1MS6 A;  4BS5 A;  1GLO A;  4I04 A;  3KX1 A;  2B1N A;  2G8E A;  2E01 A;  3BPF A;  4I05 A;  4QBB A;  3H89 A;  3MHH A;  2AU1 A;  2FUD A;  2AYN A;  1STF E;  2DC7 A;  2NQA A;  2AVW A;  3MHS A;  4MZS A;  1AIM A;  4FIP A;  3QJ3 A;  2G7Y A;  1TLO A;  2VHF A;  4YYQ A;  2XU5 A;  4CDC B;  3U8E A;  3BCN A;  1EWL A;  2H7J A;  1U9X A;  1ZCM A;  8PCH A;  3WXE A;  3PW3 A;  1PAD A;  3B79 A;  1K3B B;  4CDD B;  3PBH A;  4KLB A;  1QOL A;  1CS8 A;  1PE6 A;  2P86 A;  1A6R A;  2BDZ A;  3ERV A;  4YYV A;  1PPP A;  3QSD A;  1TU6 A;  1U5I A;  1MHW A;  6PAD A;  2YJ9 A;  3I06 A;  4G54 A;  1PCI A;  4Q8H A;  4YYU A;  1NB5 A;  3KFQ A;  3PNR A;  2C0Y A;  3IMA A;  2OP3 A;  3OF9 A;  3P5X A;  7PCK A;  3OVZ A;  2P7U A;  2R9C A;  5EGW A;  2PBH A;  2PAD A;  1BGO A;  1KFU L;  2YJ8 A;  2FTD A;  2AUX A;  1F2C A;  1EWM A;  3IEJ A;  5CVO B;  3RVX A;  3CBJ A;  3E1Z B;  3BPM A;  2G6D A;  4Q8G A;  2R9N A;  1F2B A;  1TL9 A;  1YT7 A;  1ME3 A;  2WBF X;  2NQG A;  1GEC E;  3O1G A;  4QRX A;  4CDE B;  2HHN A;  1AEC A;  4AXL A;  2FQ9 A;  1GCB A;  4YYS A;  1PBH A;  5JA7 A;  4K7C A;  2E03 A;  1CJL A;  4PAD A;  3WXF A;  3CBK A;  1NLJ A;  1VSN A;  2VHS A;  4N4Z A;  4WA6 A;  4N79 A;  4P6E A;  3D6S A;  1CV8 A;  1AU0 A;  1ZIV A;  1YAL A;  4OEM A;  5CVM A;  2YJC A;  3WXG A;  3PDF A;  3KWZ A;  1QMY A;  1FH0 A;  4W5B A;  1KHQ A;  1CPJ A;  1HUC B;  1AU2 A;  1IWD A;  4P6G A;  2CB5 A;  1X9Y A;  2P0R A;  2OUL A;  2DJG B;  4AXM A;  1BY8 A;  2O6X A;  3IHP A;  1JQP A;  3AI8 A;  1PXV A;  3KW9 A;  3H7D A;  3K8U A;  1KHP A;  2AS8 A;  2BDL A;  3KWB X;  1NB3 A;  2DC6 A;  2AYO A;  1M6D A;  4MZO A;  4HWY A;  2XU1 A;  2DCA A;  1SP4 B;  3I3T A;  1CTE A;  1CB5 A;  5CHV A;  2DZZ A;  4I07 A;  2DCD A;  4W4U A;  3P5W A;  2DC8 A;  3RVV A;  4BQV A;  2FO5 A;  3S3Q A;  1GMY A;  2FYE A;  3OVX A;  1POP A;  1AYW A;  1NQC A;  1YK8 A;  2HH5 A;  4X6H A;  4QRG A;  2B1M A;  3F5V A;  2FRQ A;  3BWK A;  2NQD B;  4CDF B;  4PI3 A;  3H6S A;  3HWN A;  9PAP A;  2FT2 A;  3HHI A;  5J94 A;  2ARY A;  2R6N A;  4PP1 A;  2R9M A;  1F2A A;  2ATO A;  2DCC A;  3HD3 A;  3IOQ A;  1MDW A;  1QXP A;  4XR7 A;  4PP2 E;  3S3R A;  2NQI A;  1AYU A;  2F1G A;  4FJC A;  3P5V A;  3K24 A;  1U9V A;  1AU4 A;  1QDQ A;  1NPZ A;  5A24 A;  2XU3 A;  3V6E A;  3IUT A;  2OZ2 A;  1MEG A;  2IPP B;  3BC3 A;  1CQD A;  4X6J A;  3CH3 X; 
#chains in the Genus database with same CATH topology
 1S4V A;  4M0W A;  1YVB A;  1UKF A;  4YVA A;  3PRP A;  4YV8 A;  1ME4 A;  1YK7 A;  2DCB A;  4DMX A;  4XUI A;  5EF4 A;  3F75 A;  2AUZ A;  2Y6E A;  3DF0 A;  4PT5 A;  3MTV A;  2AIM A;  3MOR A;  1MEM A;  3KKU A;  3RVW A;  1EWO A;  2IBI A;  4BPV A;  3B21 A;  2YJ2 A;  2XU4 A;  3NHE A;  1XKG A;  3K9M A;  2YJB A;  1KFX L;  4N8W A;  2BU3 A;  4BS6 A;  2JQG R;  1Q6K A;  3P5U A;  3E9S A;  4YYR A;  2ACT A;  3QT4 A;  1EF7 A;  1U9Q X;  2AGA A;  4YYW A;  3KSE A;  1F29 A;  1PPO A;  2GHU A;  2FRA A;  5K16 A;  4RKX A;  3HHA A;  3V6C A;  1AU3 A;  2DJF B;  3C9E A;  5EZQ A;  2HXZ A;  4W5C A;  5PAD A;  2E00 A;  4QH6 A;  1PPN A;  5FPW A;  3BOW A;  2HWK A;  3CH2 X;  1BP4 A;  1ICF A;  3LXS A;  1CVZ A;  1DF0 A;  3OIS A;  2G8J A;  3W30 A;  4DMY A;  2DC9 A;  1DKI A;  1DEU A;  4RNA A;  3TNX A;  1SNK A;  2UZJ A;  1CSB B;  4OEL A;  5KO3 A;  2R9F A;  3N3K A;  2HD5 A;  2GFO A;  3LFY A;  2PRE A;  2DZY A;  1U9W A;  4FK5 A;  1EWP A;  4ZUX U;  4BOQ A;  3GCB A;  3W31 A;  3OF8 A;  1VJV A;  1PIP A;  2FE8 A;  3H8C A;  5F02 A;  1Y08 A;  2R9O A;  4OVZ A;  4BSQ A;  3IV2 A;  5CVN B;  1MIR A;  3N3G A;  4RY2 A;  3MTN A;  2E02 A;  4RF1 A;  1BQI A;  3H8B A;  3M99 A;  3BY4 A;  1AYV A;  2CIO A;  5JZE A;  2F7D A;  1PPD A;  4OVZ B;  1O0E A;  5JH3 A;  4MM3 B;  3OQC A;  3ZUA A;  4D8I A;  1ATK A;  3O0U A;  5CHT A;  3RNV A;  4MSX A;  3USV A;  4QRV A;  2Y5B A;  4CZW A;  1ITO A;  1Y4H A;  1NL6 A;  4X6I A;  3N4C A;  1THE A;  1KXR A;  2JQF R;  2PNS A;  1MS6 A;  4BS5 A;  1GLO A;  4I04 A;  3KX1 A;  2B1N A;  2G8E A;  2E01 A;  3BPF A;  4I05 A;  4QBB A;  3H89 A;  3MHH A;  2AU1 A;  2FUD A;  2AYN A;  1STF E;  2DC7 A;  2DOS A;  2NQA A;  2AVW A;  3MHS A;  4MI7 A;  4MZS A;  1AIM A;  4FIP A;  1PVJ A;  1YZB A;  3QJ3 A;  2G7Y A;  2JTC A;  1TLO A;  2VHF A;  4YYQ A;  2XU5 A;  4CDC B;  3U8E A;  3BCN A;  1EWL A;  2H7J A;  1U9X A;  1ZCM A;  8PCH A;  3WXE A;  3PW3 A;  1PAD A;  3B79 A;  1K3B B;  2J7Q A;  4CDD B;  3PBH A;  4KLB A;  1QOL A;  3BB7 A;  1CS8 A;  1PE6 A;  2P86 A;  1A6R A;  2BDZ A;  3ERV A;  4YYV A;  1PPP A;  3QSD A;  3PT2 A;  1TU6 A;  1U5I A;  1MHW A;  6PAD A;  2YJ9 A;  3I06 A;  4G54 A;  1PCI A;  4Q8H A;  4YYU A;  1NB5 A;  3KFQ A;  3MP2 A;  3PNR A;  2C0Y A;  3PHX A;  4BOZ A;  2BTW A;  3IMA A;  4IP3 A;  2OP3 A;  3OF9 A;  3P5X A;  3PHU A;  7PCK A;  3OVZ A;  2P7U A;  2R9C A;  5EGW A;  2PBH A;  2PAD A;  1BGO A;  1KFU L;  2YJ8 A;  5EZS A;  2FTD A;  2AUX A;  3O65 A;  1F2C A;  1EWM A;  3IEJ A;  5CVO B;  4OW0 A;  3RVX A;  3CBJ A;  2JRI A;  3E1Z B;  3BPM A;  2G6D A;  4Q8G A;  2R9N A;  1F2B A;  1TL9 A;  1YT7 A;  1ME3 A;  2WBF X;  2NQG A;  2Z84 A;  1GEC E;  3O1G A;  4QRX A;  4CDE B;  2HHN A;  1AEC A;  4AXL A;  2FQ9 A;  1GCB A;  4YYS A;  1PBH A;  5JA7 A;  4K7C A;  2E03 A;  1CJL A;  4PAD A;  3WXF A;  3CBK A;  1NLJ A;  4BOS A;  1VSN A;  2VHS A;  4N4Z A;  4WA6 A;  4N79 A;  3PRM A;  4REZ A;  4P6E A;  3D6S A;  4IUM A;  1CV8 A;  1AU0 A;  1ZIV A;  1YAL A;  4OEM A;  5CVM A;  2YJC A;  3WXG A;  3PDF A;  3KWZ A;  3TRK A;  1QMY A;  1FH0 A;  4W5B A;  4D8E A;  1KHQ A;  1CPJ A;  1HUC B;  1AU2 A;  1IWD A;  2CB5 A;  3PHW A;  4P6G A;  1X9Y A;  3ZNH A;  4BOP A;  2P0R A;  2OUL A;  2DJG B;  4AXM A;  5E6J A;  1BY8 A;  4WUR A;  2O6X A;  3IHP A;  1JQP A;  3AI8 A;  1PXV A;  3KW9 A;  3H7D A;  3K8U A;  1KHP A;  2AS8 A;  2BDL A;  3KWB X;  1NB3 A;  2DC6 A;  2AYO A;  1M6D A;  4MZO A;  4HWY A;  2XU1 A;  2DCA A;  4D8B A;  4GUA A;  1SP4 B;  2J7Q C;  3I3T A;  1CTE A;  1CB5 A;  4A5U A;  4R3D A;  5CHV A;  2DZZ A;  4I07 A;  2DCD A;  4W4U A;  3P5W A;  3PSE A;  2DC8 A;  3RVV A;  4BQV A;  4XZX A;  2FO5 A;  3S3Q A;  1GMY A;  3BBA A;  2FYE A;  3OVX A;  1POP A;  1AYW A;  3MJ5 A;  1NQC A;  3IFU A;  1YK8 A;  2HH5 A;  4X6H A;  2BTW B;  4RF0 A;  4QRG A;  2B1M A;  3F5V A;  2FRQ A;  3BWK A;  4P16 A;  2NQD B;  4CDF B;  4PI3 A;  3H6S A;  3HWN A;  9PAP A;  2FT2 A;  3HHI A;  5J94 A;  3TMP A;  2ARY A;  2R6N A;  4PP1 A;  4HXD B;  2R9M A;  4ZTB A;  1F2A A;  2ATO A;  2DCC A;  3HD3 A;  3IOQ A;  1MDW A;  1QXP A;  4XR7 A;  4PP2 E;  3S3R A;  2NQI A;  1AYU A;  2F1G A;  4FJC A;  3P5V A;  3K24 A;  1U9V A;  1AU4 A;  1QDQ A;  1NPZ A;  5A24 A;  2XU3 A;  3C0R A;  3V6E A;  3IUT A;  2OZ2 A;  1MEG A;  2IPP B;  3BC3 A;  1CQD A;  4BOU A;  4X6J A;  3CH3 X; 
#chains in the Genus database with same CATH homology
 1S4V A;  1YVB A;  4NV7 A;  4YVA A;  4YV8 A;  1ME4 A;  1YK7 A;  2DCB A;  4DMX A;  4XUI A;  5EF4 A;  3F75 A;  2AUZ A;  2Y6E A;  3DF0 A;  4BGF A;  2AIM A;  3MOR A;  1MEM A;  3KKU A;  3RVW A;  1EWO A;  2IBI A;  4BPV A;  1W4T A;  2YJ2 A;  2XU4 A;  3NHE A;  1XKG A;  3K9M A;  2YJB A;  1KFX L;  4N8W A;  4BS6 A;  2JQG R;  1Q6K A;  3P5U A;  4YYR A;  2ACT A;  3QT4 A;  1EF7 A;  1U9Q X;  4YYW A;  3KSE A;  1F29 A;  1PPO A;  2GHU A;  2FRA A;  5K16 A;  3HHA A;  3V6C A;  1AU3 A;  2DJF B;  3C9E A;  2HXZ A;  4W5C A;  5PAD A;  2E00 A;  4QH6 A;  1PPN A;  5FPW A;  3BOW A;  3CH2 X;  1BP4 A;  1ICF A;  3LXS A;  1CVZ A;  1DF0 A;  3OIS A;  2G8J A;  4DMY A;  2DC9 A;  1DEU A;  3TNX A;  1SNK A;  1CSB B;  4OEL A;  2R9F A;  3N3K A;  2HD5 A;  2GFO A;  3LFY A;  2PRE A;  2DZY A;  1U9W A;  4FK5 A;  1EWP A;  4ZUX U;  3GCB A;  3D9W A;  3OF8 A;  1VJV A;  1PIP A;  3H8C A;  5F02 A;  1Y08 A;  2VFC A;  2R9O A;  4BSQ A;  3IV2 A;  5CVN B;  1MIR A;  3N3G A;  4RY2 A;  3MTN A;  2E02 A;  1BQI A;  4C5P A;  3H8B A;  3M99 A;  1AYV A;  2CIO A;  2F7D A;  1PPD A;  1O0E A;  5JH3 A;  3ZUA A;  1ATK A;  3O0U A;  5CHT A;  4MSX A;  3USV A;  4QRV A;  1W5R A;  2Y5B A;  4CZW A;  1ITO A;  1Y4H A;  1NL6 A;  4X6I A;  3N4C A;  1THE A;  1KXR A;  2JQF R;  2PNS A;  1MS6 A;  4BS5 A;  1GLO A;  4I04 A;  3KX1 A;  2B1N A;  2G8E A;  2E01 A;  3BPF A;  1E2T A;  4I05 A;  4QBB A;  3H89 A;  3MHH A;  2AU1 A;  2FUD A;  2AYN A;  1STF E;  2DC7 A;  2NQA A;  2AVW A;  3MHS A;  4MZS A;  1AIM A;  4FIP A;  3QJ3 A;  2G7Y A;  1TLO A;  2VHF A;  4YYQ A;  2XU5 A;  4CDC B;  3U8E A;  3BCN A;  1EWL A;  2H7J A;  1U9X A;  1ZCM A;  8PCH A;  3WXE A;  3PW3 A;  1PAD A;  3B79 A;  1K3B B;  4CDD B;  3PBH A;  4KLB A;  1QOL A;  1CS8 A;  1PE6 A;  2P86 A;  1A6R A;  2BDZ A;  3ERV A;  4YYV A;  1PPP A;  3QSD A;  1TU6 A;  1U5I A;  1MHW A;  6PAD A;  2YJ9 A;  3I06 A;  4G54 A;  1PCI A;  4Q8H A;  4YYU A;  1NB5 A;  3KFQ A;  3PNR A;  2C0Y A;  3IMA A;  2OP3 A;  3OF9 A;  3P5X A;  7PCK A;  3OVZ A;  2P7U A;  2R9C A;  5EGW A;  2PBH A;  2PAD A;  1BGO A;  1KFU L;  2YJ8 A;  2FTD A;  2AUX A;  1F2C A;  1EWM A;  3IEJ A;  5CVO B;  3RVX A;  3CBJ A;  3E1Z B;  3BPM A;  2G6D A;  4Q8G A;  2R9N A;  1F2B A;  1TL9 A;  2VFB A;  1YT7 A;  1ME3 A;  2WBF X;  2NQG A;  1GEC E;  3O1G A;  4QRX A;  4CDE B;  2HHN A;  1AEC A;  4AXL A;  2FQ9 A;  1GCB A;  4YYS A;  1PBH A;  5JA7 A;  4K7C A;  2E03 A;  1CJL A;  4PAD A;  3WXF A;  3CBK A;  1NLJ A;  1W6F A;  1VSN A;  2VHS A;  4N4Z A;  4WA6 A;  4N79 A;  4P6E A;  3D6S A;  1CV8 A;  1AU0 A;  1ZIV A;  1YAL A;  4OEM A;  5CVM A;  2YJC A;  3WXG A;  3PDF A;  3KWZ A;  1QMY A;  1FH0 A;  4W5B A;  1KHQ A;  1CPJ A;  1HUC B;  1AU2 A;  1IWD A;  2CB5 A;  4P6G A;  1X9Y A;  2P0R A;  2OUL A;  2DJG B;  4AXM A;  1BY8 A;  2O6X A;  3IHP A;  1JQP A;  3AI8 A;  1PXV A;  3KW9 A;  3H7D A;  3K8U A;  1KHP A;  2AS8 A;  2BDL A;  3KWB X;  1NB3 A;  2DC6 A;  2AYO A;  1M6D A;  4MZO A;  4HWY A;  2XU1 A;  2DCA A;  1SP4 B;  3LTW A;  3I3T A;  1CTE A;  1CB5 A;  5CHV A;  2DZZ A;  4I07 A;  2DCD A;  4W4U A;  3P5W A;  2DC8 A;  3RVV A;  4BQV A;  2FO5 A;  3S3Q A;  1GMY A;  2FYE A;  3OVX A;  1POP A;  1AYW A;  1NQC A;  2BSZ A;  1YK8 A;  2HH5 A;  4X6H A;  4QRG A;  2B1M A;  3F5V A;  2FRQ A;  3BWK A;  2NQD B;  4CDF B;  4PI3 A;  3H6S A;  3HWN A;  9PAP A;  2FT2 A;  3HHI A;  5J94 A;  2ARY A;  2R6N A;  4PP1 A;  4B55 A;  2R9M A;  4GUZ A;  1F2A A;  2ATO A;  2DCC A;  3HD3 A;  3IOQ A;  1MDW A;  1QXP A;  4XR7 A;  4NV8 A;  4PP2 E;  3S3R A;  2NQI A;  1AYU A;  2F1G A;  4FJC A;  3P5V A;  3K24 A;  1U9V A;  1AU4 A;  1GX3 A;  1QDQ A;  1NPZ A;  5A24 A;  2XU3 A;  3V6E A;  3IUT A;  2OZ2 A;  1MEG A;  2IPP B;  3BC3 A;  1CQD A;  4X6J A;  3CH3 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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