2R9MA

Cathepsin s complexed with compound 15
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
217
structure length
217
Chain Sequence
LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design and Synthesis of Reversible Inhibitors of Cathepsin S: alpha,alpha-Disubstitution at the P1 Residue Provides Potent Inhibitors in Cellular Assays and In Vivo Models of Antigen Presentation
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin S
total genus 68
structure length 217
sequence length 217
chains with identical sequence B
ec nomenclature ec 3.4.22.27: Cathepsin S.
pdb deposition date 2007-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2r9mA00
2R6NA 3OVXA 4PP2E 4Q8GA 2O6XA 1ZIVA 3IV2A 2NQGA 2HXZA 1PBHA 4W5CA 3NHEA 1YK7A 3HD3A 3M99A 4CDCB 1SNKA 1NB5A 4X6IA 1YT7A 1F2CA 2E01A 4KLBA 1F29A 5CHTA 1EWOA 1BQIA 5EF4A 1PPOA 1ME4A 3BPMA 3OVZA 2IPPB 3IEJA 3N4CA 2DC8A 2DZYA 3HWNA 1PPDA 1DEUA 1BP4A 1GLOA 5CVMA 4YYWA 3H7DA 3KX1A 1MS6A 2DZZA 2P0RA 1ME3A 3BWKA 2ACTA 3K8UA 4WA6A 2AUXA 3KFQA 5EGWA 2R9OA 5PADA 1U9QX 4N8WA 1XKGA 4N4ZA 4MSXA 3ERVA 2Y5BA 4OELA 1NLJA 1IWDA 1Y4HA 4DMXA 2FYEA 3KWZA 3OF8A 2OZ2A 2NQIA 1PCIA 1NPZA 1AU4A 1DF0A 4AXMA 2R9NA 2XU4A 4MZSA 1AYUA 2FO5A 2HH5A 1U9XA 3E1ZB 3BCNA 5CHVA 1QOLA 4PI3A 3P5UA 2YJ2A 9PAPA 2CB5A 2FUDA 4QRXA 2JQGR 2FQ9A 1X9YA 4X6JA 5JA7A 1QMYA 2AUZA 2BDLA 1CQDA 2G8JA 2DCAA 1GMYA 4K7CA 1PE6A 3PBHA 2B1MA 5FPWA 1AYWA 2OP3A 1MIRA 2E00A 1MHWA 3MHHA 4YYVA 2OULA 1NL6A 1NQCA 1KFUL 3H8BA 3IUTA 3ZUAA 4I07A 1F2BA 4BS6A 2GFOA 3PDFA 3RVVA 5JH3A 1CSBB 2VHFA 3C9EA 3S3RA 2F7DA 1U9VA 3V6CA 2FRAA 5CVNB 1JQPA 1ZCMA 1EF7A 4P6EA 1ITOA 2G6DA 1STFE 2AYNA 2FTDA 2DCBA 1BY8A 4FIPA 4OEMA 4Q8HA 1CS8A 3PNRA 2AIMA 3PW3A 3KWBX 4BSQA 1KHPA 4MZOA 1PADA 2HHNA 1GCBA 2AVWA 3D6SA 4PP1A 2R9CA 1CB5A 1KFXL 4XR7A 1EWLA 3DF0A 3IHPA 4YYUA 1GECE 2PNSA 1CTEA 3K9MA 3HHIA 2F1GA 1MDWA 3P5WA 2P7UA 1AU3A 1THEA 4QH6A 4ZUXU 3F75A 1AYVA 3MHSA 4P6GA 1CPJA 3N3KA 2DCDA 3QJ3A 1AECA 3N3GA 3RVWA 2BDZA 4BQVA 2H7JA 4AXLA 2B1NA 3S3QA 2DC7A 2IBIA 6PADA 1AU2A 2XU5A 3MORA 3MTNA 1AIMA 3HHAA 4HWYA 1O0EA 3P5XA 4I05A 4CZWA 7PCKA 4DMYA 3BOWA 4I04A 1TLOA 1Q6KA 5F02A 2NQAA 1A6RA 4X6HA 4CDEB 2AYOA 3H6SA 3BPFA 2ARYA 1QXPA 2YJBA 1M6DA 5CVOB 8PCHA 1AU0A 1TL9A 1MEGA 3V6EA 4FK5A 3OISA 3WXEA 3CBJA 2C0YA 2JQFR 5A24A 3O0UA 1EWPA 3P5VA 1PPNA 3BC3A 3GCBA 3KSEA 4YYRA 4G54A 2FT2A 4YYQA 3IOQA 3QSDA 2R9FA 1VJVA 4YVAA 3U8EA 2DC9A 3CH3X 1YALA 3CBKA 2PADA 1VSNA 4N79A 1F2AA 3KKUA 3CH2X 4W4UA 3LFYA 3IMAA 2DCCA 2Y6EA 2DC6A 1NB3A 1QDQA 1U5IA 3I06A 2VHSA 3WXGA 1SP4B 2CIOA 3I3TA 5J94A 1KXRA 2PREA 1CJLA 1PPPA 1FH0A 4YV8A 1POPA 1ICFA 3K24A 2YJ8A 3TNXA 1S4VA 1MEMA 3WXFA 2XU3A 1PXVA 2PBHA 4BS5A 4CDFB 1YK8A 1Y08A 2DJFB 1CVZA 2YJ9A 2XU1A 4PADA 1PIPA 4RY2A 2AU1A 1KHQA 1BGOA 3AI8A 2G7YA 2HD5A 4QRGA 1ATKA 2NQDB 2P86A 4BPVA 2E02A 2WBFX 5K16A 3LXSA 2G8EA 2R9MA 3H8CA 1HUCB 3F5VA 2ATOA 2GHUA 2YJCA 2AS8A 3H89A 1U9WA 2DJGB 3OF9A 1TU6A 3USVA 4FJCA 1CV8A 3RVXA 2FRQA 4XUIA 2E03A 1YVBA 1K3BB 4QRVA 3QT4A 4YYSA 4QBBA 4W5BA 1EWMA 3B79A 3O1GA 4CDDB 3KW9A
chains in the Genus database with same CATH superfamily
2R6NA 3OVXA 2HWKA 4PP2E 4Q8GA 4P16A 2O6XA 1ZIVA 3PT2A 3IV2A 2NQGA 4ZTBA 2HXZA 1PBHA 4W5CA 3NHEA 1YK7A 3HD3A 3M99A 4CDCB 3TMPA 1SNKA 4OW0A 1NB5A 4MI7A 4X6IA 1YT7A 1DKIA 1F2CA 2E01A 4KLBA 1F29A 3TRKA 5CHTA 1EWOA 1BQIA 2BTWA 5EF4A 1PPOA 3ZNHA 4RKXA 1ME4A 4XZXA 3BPMA 3OVZA 2IPPB 3IEJA 3N4CA 2DC8A 2DZYA 3HWNA 1PPDA 5KO3A 1DEUA 1BP4A 1GLOA 5CVMA 4D8EA 4YYWA 3H7DA 3KX1A 1MS6A 2DZZA 2P0RA 1ME3A 3C0RA 3BWKA 2ACTA 3K8UA 4WA6A 5E6JA 2AUXA 3KFQA 5EGWA 2R9OA 3RNVA 5PADA 1U9QX 4N8WA 1XKGA 4N4ZA 3ERVA 4MSXA 2Y5BA 4OELA 1NLJA 1IWDA 1Y4HA 4DMXA 2FYEA 2UZJA 3KWZA 3OF8A 2OZ2A 4PT5A 2NQIA 1PCIA 1NPZA 1AU4A 5JZEA 1DF0A 4AXMA 2R9NA 2XU4A 4MZSA 3W31A 1AYUA 2FO5A 2HH5A 1U9XA 3E1ZB 3BCNA 5CHVA 1QOLA 4PI3A 3P5UA 2YJ2A 9PAPA 2CB5A 2FUDA 2FE8A 4QRXA 2JQGR 2FQ9A 1X9YA 4X6JA 5JA7A 1QMYA 2AUZA 2BDLA 1CQDA 2G8JA 4GUAA 2DCAA 1GMYA 4K7CA 1PE6A 3PBHA 1YZBA 2B1MA 5FPWA 1AYWA 2OP3A 2JTCA 1MIRA 2E00A 1MHWA 3MHHA 4YYVA 2OULA 1UKFA 3MJ5A 3BY4A 1NL6A 1NQCA 3PHXA 1KFUL 3H8BA 3IUTA 3ZUAA 4I07A 1F2BA 4BS6A 2GFOA 3PDFA 3RVVA 5JH3A 1CSBB 2VHFA 3C9EA 3S3RA 2F7DA 1U9VA 3V6CA 2FRAA 5CVNB 1JQPA 1ZCMA 1EF7A 4P6EA 1ITOA 2G6DA 1STFE 2AYNA 2FTDA 2DCBA 1BY8A 4FIPA 4OEMA 4Q8HA 1CS8A 3PNRA 2AIMA 3PW3A 3KWBX 4BSQA 2J7QC 1KHPA 4MZOA 1PADA 2HHNA 1GCBA 2AVWA 3D6SA 4PP1A 2R9CA 1CB5A 1KFXL 4XR7A 4BOQA 1EWLA 3DF0A 3IHPA 3W30A 4YYUA 1GECE 2PNSA 1CTEA 3BB7A 3K9MA 3HHIA 1PVJA 2F1GA 1MDWA 5EZSA 4WURA 3P5WA 2P7UA 1AU3A 2BTWB 1THEA 4QH6A 4ZUXU 3F75A 1AYVA 3MHSA 4IP3A 4P6GA 1CPJA 3N3KA 4HXDB 2DCDA 3QJ3A 4IUMA 1AECA 3N3GA 3RVWA 2BDZA 3B21A 4BQVA 2H7JA 4AXLA 2B1NA 4A5UA 3S3QA 4REZA 2DC7A 2IBIA 6PADA 1AU2A 2XU5A 3MORA 3MTNA 4MM3B 1AIMA 3HHAA 4HWYA 1O0EA 4D8IA 3P5XA 4I05A 4CZWA 7PCKA 4DMYA 3BOWA 4I04A 1TLOA 1Q6KA 5F02A 2NQAA 1A6RA 3PHUA 4X6HA 4CDEB 4OVZA 2AYOA 3H6SA 3BPFA 2ARYA 1QXPA 2DOSA 2YJBA 1M6DA 5CVOB 8PCHA 1AU0A 1TL9A 1MEGA 3V6EA 4FK5A 4BOPA 3OISA 2J7QA 3WXEA 4M0WA 4RF1A 3CBJA 2C0YA 2JQFR 5A24A 3O0UA 1EWPA 3P5VA 1PPNA 5EZQA 3BC3A 3GCBA 3KSEA 4YYRA 4G54A 4OVZB 2FT2A 4YYQA 3IOQA 2R9FA 3QSDA 1VJVA 4YVAA 3U8EA 2DC9A 3CH3X 1YALA 3CBKA 2PADA 4BOZA 1VSNA 4R3DA 4BOUA 4N79A 1F2AA 3KKUA 3CH2X 4W4UA 3LFYA 3IMAA 2DCCA 2Y6EA 3O65A 2DC6A 2BU3A 1NB3A 1QDQA 3PRPA 1U5IA 2JRIA 3I06A 3PHWA 2VHSA 3WXGA 1SP4B 2CIOA 3I3TA 5J94A 1KXRA 2PREA 4RNAA 1CJLA 3MTVA 3BBAA 1PPPA 1FH0A 4YV8A 1POPA 1ICFA 3K24A 3PSEA 2YJ8A 3TNXA 1S4VA 4RF0A 3MP2A 2Z84A 1MEMA 4BOSA 3E9SA 3WXFA 2XU3A 1PXVA 2PBHA 3IFUA 4BS5A 4CDFB 1YK8A 1Y08A 2DJFB 1CVZA 2YJ9A 2XU1A 4PADA 1PIPA 3OQCA 4D8BA 4RY2A 2AU1A 1KHQA 1BGOA 3AI8A 2G7YA 2HD5A 4QRGA 1ATKA 2NQDB 2P86A 4BPVA 2E02A 2WBFX 5K16A 3LXSA 2G8EA 2R9MA 3PRMA 3H8CA 1HUCB 3F5VA 2ATOA 2GHUA 2YJCA 2AS8A 3H89A 3OF9A 1U9WA 2DJGB 1TU6A 3USVA 4FJCA 1CV8A 3RVXA 2FRQA 4XUIA 2E03A 1YVBA 1K3BB 4QRVA 3QT4A 4YYSA 4QBBA 4W5BA 1EWMA 2AGAA 3B79A 3O1GA 4CDDB 3KW9A
chains in the Genus database with same CATH topology
2R6NA 3OVXA 4PP2E 4Q8GA 2O6XA 1ZIVA 3IV2A 2NQGA 2HXZA 1PBHA 4W5CA 4NV8A 3NHEA 1YK7A 3HD3A 3M99A 4CDCB 1SNKA 1NB5A 4X6IA 1YT7A 1F2CA 2E01A 4KLBA 1F29A 5CHTA 1EWOA 1BQIA 5EF4A 1PPOA 1ME4A 3BPMA 3OVZA 2IPPB 3IEJA 3N4CA 2DC8A 2DZYA 3HWNA 1PPDA 1DEUA 1BP4A 1GLOA 5CVMA 4YYWA 3H7DA 3KX1A 1MS6A 2DZZA 2P0RA 1ME3A 3BWKA 2ACTA 3K8UA 4WA6A 2AUXA 3KFQA 5EGWA 2R9OA 5PADA 1W4TA 4NV7A 1U9QX 4N8WA 1XKGA 4N4ZA 4MSXA 3ERVA 2Y5BA 4OELA 1NLJA 1IWDA 1Y4HA 4DMXA 2FYEA 3KWZA 3OF8A 2OZ2A 2NQIA 1PCIA 1NPZA 1AU4A 1DF0A 4AXMA 2R9NA 2XU4A 4MZSA 1AYUA 2FO5A 2HH5A 1U9XA 3E1ZB 3BCNA 5CHVA 1QOLA 4PI3A 3P5UA 2YJ2A 9PAPA 2CB5A 2FUDA 4QRXA 2JQGR 2FQ9A 1X9YA 4X6JA 5JA7A 1QMYA 2AUZA 2BDLA 1CQDA 2G8JA 2VFCA 2DCAA 1GMYA 4K7CA 1PE6A 3PBHA 2B1MA 5FPWA 1AYWA 2OP3A 1MIRA 2E00A 1MHWA 3MHHA 4YYVA 2OULA 2BSZA 1NL6A 1NQCA 1KFUL 3H8BA 3IUTA 3ZUAA 4I07A 1F2BA 4BS6A 2GFOA 3PDFA 3RVVA 5JH3A 1CSBB 2VHFA 3C9EA 3S3RA 2F7DA 1U9VA 3V6CA 2FRAA 5CVNB 1JQPA 1ZCMA 1EF7A 4P6EA 1ITOA 2G6DA 1STFE 2AYNA 2FTDA 2DCBA 4BGFA 2VFBA 1BY8A 4FIPA 4OEMA 4Q8HA 1CS8A 3PNRA 2AIMA 3PW3A 1W5RA 3KWBX 4BSQA 1KHPA 4MZOA 1PADA 2HHNA 1GCBA 2AVWA 3D6SA 4PP1A 2R9CA 1CB5A 1KFXL 4XR7A 1EWLA 3DF0A 3IHPA 4YYUA 1GECE 2PNSA 1CTEA 3K9MA 3HHIA 2F1GA 1MDWA 3P5WA 2P7UA 1AU3A 1THEA 4QH6A 4ZUXU 3F75A 1AYVA 3MHSA 1E2TA 4P6GA 1CPJA 3N3KA 2DCDA 3QJ3A 1AECA 3N3GA 3RVWA 2BDZA 4BQVA 2H7JA 4AXLA 2B1NA 3S3QA 1GX3A 2DC7A 2IBIA 6PADA 1AU2A 2XU5A 3MORA 3MTNA 1AIMA 3HHAA 4HWYA 1O0EA 3P5XA 4I05A 4CZWA 7PCKA 4DMYA 3BOWA 4I04A 1TLOA 1Q6KA 4C5PA 5F02A 2NQAA 1A6RA 4X6HA 4CDEB 2AYOA 3H6SA 3BPFA 2ARYA 1QXPA 2YJBA 1M6DA 5CVOB 4GUZA 8PCHA 1AU0A 1TL9A 1MEGA 3V6EA 4FK5A 3OISA 3WXEA 3CBJA 2C0YA 2JQFR 5A24A 3O0UA 1EWPA 3P5VA 1PPNA 3BC3A 3GCBA 3KSEA 4YYRA 4G54A 2FT2A 4YYQA 3IOQA 3QSDA 2R9FA 1VJVA 4YVAA 3U8EA 2DC9A 3CH3X 1YALA 3CBKA 2PADA 1VSNA 4N79A 1F2AA 3KKUA 3CH2X 4W4UA 3LFYA 3IMAA 2DCCA 2Y6EA 2DC6A 1NB3A 1QDQA 1U5IA 3I06A 2VHSA 3LTWA 3WXGA 1SP4B 2CIOA 3I3TA 5J94A 1KXRA 1W6FA 2PREA 1CJLA 1PPPA 1FH0A 4YV8A 1POPA 1ICFA 3K24A 2YJ8A 3TNXA 1S4VA 1MEMA 3WXFA 2XU3A 1PXVA 3D9WA 2PBHA 4BS5A 4CDFB 1YK8A 1Y08A 2DJFB 1CVZA 2YJ9A 2XU1A 4PADA 1PIPA 4RY2A 2AU1A 1KHQA 1BGOA 3AI8A 2G7YA 2HD5A 4QRGA 1ATKA 2NQDB 2P86A 4B55A 4BPVA 2E02A 2WBFX 5K16A 3LXSA 2G8EA 2R9MA 3H8CA 1HUCB 3F5VA 2ATOA 2GHUA 2YJCA 2AS8A 3H89A 1U9WA 2DJGB 3OF9A 1TU6A 3USVA 4FJCA 1CV8A 3RVXA 2FRQA 4XUIA 2E03A 1YVBA 1K3BB 4QRVA 3QT4A 4YYSA 4QBBA 4W5BA 1EWMA 3B79A 3O1GA 4CDDB 3KW9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R6N A;  3OVX A;  4PP2 E;  4Q8G A;  2O6X A;  1ZIV A;  3IV2 A;  2NQG A;  2HXZ A;  1PBH A;  4W5C A;  3NHE A;  1YK7 A;  3HD3 A;  3M99 A;  4CDC B;  1SNK A;  1NB5 A;  4X6I A;  1YT7 A;  1F2C A;  2E01 A;  4KLB A;  1F29 A;  5CHT A;  1EWO A;  1BQI A;  5EF4 A;  1PPO A;  1ME4 A;  3BPM A;  3OVZ A;  2IPP B;  3IEJ A;  3N4C A;  2DC8 A;  2DZY A;  3HWN A;  1PPD A;  1DEU A;  1BP4 A;  1GLO A;  5CVM A;  4YYW A;  3H7D A;  3KX1 A;  1MS6 A;  2DZZ A;  2P0R A;  1ME3 A;  3BWK A;  2ACT A;  3K8U A;  4WA6 A;  2AUX A;  3KFQ A;  5EGW A;  2R9O A;  5PAD A;  1U9Q X;  4N8W A;  1XKG A;  4N4Z A;  4MSX A;  3ERV A;  2Y5B A;  4OEL A;  1NLJ A;  1IWD A;  1Y4H A;  4DMX A;  2FYE A;  3KWZ A;  3OF8 A;  2OZ2 A;  2NQI A;  1PCI A;  1NPZ A;  1AU4 A;  1DF0 A;  4AXM A;  2R9N A;  2XU4 A;  4MZS A;  1AYU A;  2FO5 A;  2HH5 A;  1U9X A;  3E1Z B;  3BCN A;  5CHV A;  1QOL A;  4PI3 A;  3P5U A;  2YJ2 A;  9PAP A;  2CB5 A;  2FUD A;  4QRX A;  2JQG R;  2FQ9 A;  1X9Y A;  4X6J A;  5JA7 A;  1QMY A;  2AUZ A;  2BDL A;  1CQD A;  2G8J A;  2DCA A;  1GMY A;  4K7C A;  1PE6 A;  3PBH A;  2B1M A;  5FPW A;  1AYW A;  2OP3 A;  1MIR A;  2E00 A;  1MHW A;  3MHH A;  4YYV A;  2OUL A;  1NL6 A;  1NQC A;  1KFU L;  3H8B A;  3IUT A;  3ZUA A;  4I07 A;  1F2B A;  4BS6 A;  2GFO A;  3PDF A;  3RVV A;  5JH3 A;  1CSB B;  2VHF A;  3C9E A;  3S3R A;  2F7D A;  1U9V A;  3V6C A;  2FRA A;  5CVN B;  1JQP A;  1ZCM A;  1EF7 A;  4P6E A;  1ITO A;  2G6D A;  1STF E;  2AYN A;  2FTD A;  2DCB A;  1BY8 A;  4FIP A;  4OEM A;  4Q8H A;  1CS8 A;  3PNR A;  2AIM A;  3PW3 A;  3KWB X;  4BSQ A;  1KHP A;  4MZO A;  1PAD A;  2HHN A;  1GCB A;  2AVW A;  3D6S A;  4PP1 A;  2R9C A;  1CB5 A;  1KFX L;  4XR7 A;  1EWL A;  3DF0 A;  3IHP A;  4YYU A;  1GEC E;  2PNS A;  1CTE A;  3K9M A;  3HHI A;  2F1G A;  1MDW A;  3P5W A;  2P7U A;  1AU3 A;  1THE A;  4QH6 A;  4ZUX U;  3F75 A;  1AYV A;  3MHS A;  4P6G A;  1CPJ A;  3N3K A;  2DCD A;  3QJ3 A;  1AEC A;  3N3G A;  3RVW A;  2BDZ A;  4BQV A;  2H7J A;  4AXL A;  2B1N A;  3S3Q A;  2DC7 A;  2IBI A;  6PAD A;  1AU2 A;  2XU5 A;  3MOR A;  3MTN A;  1AIM A;  3HHA A;  4HWY A;  1O0E A;  3P5X A;  4I05 A;  4CZW A;  7PCK A;  4DMY A;  3BOW A;  4I04 A;  1TLO A;  1Q6K A;  5F02 A;  2NQA A;  1A6R A;  4X6H A;  4CDE B;  2AYO A;  3H6S A;  3BPF A;  2ARY A;  1QXP A;  2YJB A;  1M6D A;  5CVO B;  8PCH A;  1AU0 A;  1TL9 A;  1MEG A;  3V6E A;  4FK5 A;  3OIS A;  3WXE A;  3CBJ A;  2C0Y A;  2JQF R;  5A24 A;  3O0U A;  1EWP A;  3P5V A;  1PPN A;  3BC3 A;  3GCB A;  3KSE A;  4YYR A;  4G54 A;  2FT2 A;  4YYQ A;  3IOQ A;  3QSD A;  2R9F A;  1VJV A;  4YVA A;  3U8E A;  2DC9 A;  3CH3 X;  1YAL A;  3CBK A;  2PAD A;  1VSN A;  4N79 A;  1F2A A;  3KKU A;  3CH2 X;  4W4U A;  3LFY A;  3IMA A;  2DCC A;  2Y6E A;  2DC6 A;  1NB3 A;  1QDQ A;  1U5I A;  3I06 A;  2VHS A;  3WXG A;  1SP4 B;  2CIO A;  3I3T A;  5J94 A;  1KXR A;  2PRE A;  1CJL A;  1PPP A;  1FH0 A;  4YV8 A;  1POP A;  1ICF A;  3K24 A;  2YJ8 A;  3TNX A;  1S4V A;  1MEM A;  3WXF A;  2XU3 A;  1PXV A;  2PBH A;  4BS5 A;  4CDF B;  1YK8 A;  1Y08 A;  2DJF B;  1CVZ A;  2YJ9 A;  2XU1 A;  4PAD A;  1PIP A;  4RY2 A;  2AU1 A;  1KHQ A;  1BGO A;  3AI8 A;  2G7Y A;  2HD5 A;  4QRG A;  1ATK A;  2NQD B;  2P86 A;  4BPV A;  2E02 A;  2WBF X;  5K16 A;  3LXS A;  2G8E A;  2R9M A;  3H8C A;  1HUC B;  3F5V A;  2ATO A;  2GHU A;  2YJC A;  2AS8 A;  3H89 A;  1U9W A;  2DJG B;  3OF9 A;  1TU6 A;  3USV A;  4FJC A;  1CV8 A;  3RVX A;  2FRQ A;  4XUI A;  2E03 A;  1YVB A;  1K3B B;  4QRV A;  3QT4 A;  4YYS A;  4QBB A;  4W5B A;  1EWM A;  3B79 A;  3O1G A;  4CDD B;  3KW9 A; 
#chains in the Genus database with same CATH topology
 2R6N A;  3OVX A;  2HWK A;  4PP2 E;  4Q8G A;  4P16 A;  2O6X A;  1ZIV A;  3PT2 A;  3IV2 A;  2NQG A;  4ZTB A;  2HXZ A;  1PBH A;  4W5C A;  3NHE A;  1YK7 A;  3HD3 A;  3M99 A;  4CDC B;  3TMP A;  1SNK A;  4OW0 A;  1NB5 A;  4MI7 A;  4X6I A;  1YT7 A;  1DKI A;  1F2C A;  2E01 A;  4KLB A;  1F29 A;  3TRK A;  5CHT A;  1EWO A;  1BQI A;  2BTW A;  5EF4 A;  1PPO A;  3ZNH A;  4RKX A;  1ME4 A;  4XZX A;  3BPM A;  3OVZ A;  2IPP B;  3IEJ A;  3N4C A;  2DC8 A;  2DZY A;  3HWN A;  1PPD A;  5KO3 A;  1DEU A;  1BP4 A;  1GLO A;  5CVM A;  4D8E A;  4YYW A;  3H7D A;  3KX1 A;  1MS6 A;  2DZZ A;  2P0R A;  1ME3 A;  3C0R A;  3BWK A;  2ACT A;  3K8U A;  4WA6 A;  5E6J A;  2AUX A;  3KFQ A;  5EGW A;  2R9O A;  3RNV A;  5PAD A;  1U9Q X;  4N8W A;  1XKG A;  4N4Z A;  3ERV A;  4MSX A;  2Y5B A;  4OEL A;  1NLJ A;  1IWD A;  1Y4H A;  4DMX A;  2FYE A;  2UZJ A;  3KWZ A;  3OF8 A;  2OZ2 A;  4PT5 A;  2NQI A;  1PCI A;  1NPZ A;  1AU4 A;  5JZE A;  1DF0 A;  4AXM A;  2R9N A;  2XU4 A;  4MZS A;  3W31 A;  1AYU A;  2FO5 A;  2HH5 A;  1U9X A;  3E1Z B;  3BCN A;  5CHV A;  1QOL A;  4PI3 A;  3P5U A;  2YJ2 A;  9PAP A;  2CB5 A;  2FUD A;  2FE8 A;  4QRX A;  2JQG R;  2FQ9 A;  1X9Y A;  4X6J A;  5JA7 A;  1QMY A;  2AUZ A;  2BDL A;  1CQD A;  2G8J A;  4GUA A;  2DCA A;  1GMY A;  4K7C A;  1PE6 A;  3PBH A;  1YZB A;  2B1M A;  5FPW A;  1AYW A;  2OP3 A;  2JTC A;  1MIR A;  2E00 A;  1MHW A;  3MHH A;  4YYV A;  2OUL A;  1UKF A;  3MJ5 A;  3BY4 A;  1NL6 A;  1NQC A;  3PHX A;  1KFU L;  3H8B A;  3IUT A;  3ZUA A;  4I07 A;  1F2B A;  4BS6 A;  2GFO A;  3PDF A;  3RVV A;  5JH3 A;  1CSB B;  2VHF A;  3C9E A;  3S3R A;  2F7D A;  1U9V A;  3V6C A;  2FRA A;  5CVN B;  1JQP A;  1ZCM A;  1EF7 A;  4P6E A;  1ITO A;  2G6D A;  1STF E;  2AYN A;  2FTD A;  2DCB A;  1BY8 A;  4FIP A;  4OEM A;  4Q8H A;  1CS8 A;  3PNR A;  2AIM A;  3PW3 A;  3KWB X;  4BSQ A;  2J7Q C;  1KHP A;  4MZO A;  1PAD A;  2HHN A;  1GCB A;  2AVW A;  3D6S A;  4PP1 A;  2R9C A;  1CB5 A;  1KFX L;  4XR7 A;  4BOQ A;  1EWL A;  3DF0 A;  3IHP A;  3W30 A;  4YYU A;  1GEC E;  2PNS A;  1CTE A;  3BB7 A;  3K9M A;  3HHI A;  1PVJ A;  2F1G A;  1MDW A;  5EZS A;  4WUR A;  3P5W A;  2P7U A;  1AU3 A;  2BTW B;  1THE A;  4QH6 A;  4ZUX U;  3F75 A;  1AYV A;  3MHS A;  4IP3 A;  4P6G A;  1CPJ A;  3N3K A;  4HXD B;  2DCD A;  3QJ3 A;  4IUM A;  1AEC A;  3N3G A;  3RVW A;  2BDZ A;  3B21 A;  4BQV A;  2H7J A;  4AXL A;  2B1N A;  4A5U A;  3S3Q A;  4REZ A;  2DC7 A;  2IBI A;  6PAD A;  1AU2 A;  2XU5 A;  3MOR A;  3MTN A;  4MM3 B;  1AIM A;  3HHA A;  4HWY A;  1O0E A;  4D8I A;  3P5X A;  4I05 A;  4CZW A;  7PCK A;  4DMY A;  3BOW A;  4I04 A;  1TLO A;  1Q6K A;  5F02 A;  2NQA A;  1A6R A;  3PHU A;  4X6H A;  4CDE B;  4OVZ A;  2AYO A;  3H6S A;  3BPF A;  2ARY A;  1QXP A;  2DOS A;  2YJB A;  1M6D A;  5CVO B;  8PCH A;  1AU0 A;  1TL9 A;  1MEG A;  3V6E A;  4FK5 A;  4BOP A;  3OIS A;  2J7Q A;  3WXE A;  4M0W A;  4RF1 A;  3CBJ A;  2C0Y A;  2JQF R;  5A24 A;  3O0U A;  1EWP A;  3P5V A;  1PPN A;  5EZQ A;  3BC3 A;  3GCB A;  3KSE A;  4YYR A;  4G54 A;  4OVZ B;  2FT2 A;  4YYQ A;  3IOQ A;  2R9F A;  3QSD A;  1VJV A;  4YVA A;  3U8E A;  2DC9 A;  3CH3 X;  1YAL A;  3CBK A;  2PAD A;  4BOZ A;  1VSN A;  4R3D A;  4BOU A;  4N79 A;  1F2A A;  3KKU A;  3CH2 X;  4W4U A;  3LFY A;  3IMA A;  2DCC A;  2Y6E A;  3O65 A;  2DC6 A;  2BU3 A;  1NB3 A;  1QDQ A;  3PRP A;  1U5I A;  2JRI A;  3I06 A;  3PHW A;  2VHS A;  3WXG A;  1SP4 B;  2CIO A;  3I3T A;  5J94 A;  1KXR A;  2PRE A;  4RNA A;  1CJL A;  3MTV A;  3BBA A;  1PPP A;  1FH0 A;  4YV8 A;  1POP A;  1ICF A;  3K24 A;  3PSE A;  2YJ8 A;  3TNX A;  1S4V A;  4RF0 A;  3MP2 A;  2Z84 A;  1MEM A;  4BOS A;  3E9S A;  3WXF A;  2XU3 A;  1PXV A;  2PBH A;  3IFU A;  4BS5 A;  4CDF B;  1YK8 A;  1Y08 A;  2DJF B;  1CVZ A;  2YJ9 A;  2XU1 A;  4PAD A;  1PIP A;  3OQC A;  4D8B A;  4RY2 A;  2AU1 A;  1KHQ A;  1BGO A;  3AI8 A;  2G7Y A;  2HD5 A;  4QRG A;  1ATK A;  2NQD B;  2P86 A;  4BPV A;  2E02 A;  2WBF X;  5K16 A;  3LXS A;  2G8E A;  2R9M A;  3PRM A;  3H8C A;  1HUC B;  3F5V A;  2ATO A;  2GHU A;  2YJC A;  2AS8 A;  3H89 A;  3OF9 A;  1U9W A;  2DJG B;  1TU6 A;  3USV A;  4FJC A;  1CV8 A;  3RVX A;  2FRQ A;  4XUI A;  2E03 A;  1YVB A;  1K3B B;  4QRV A;  3QT4 A;  4YYS A;  4QBB A;  4W5B A;  1EWM A;  2AGA A;  3B79 A;  3O1G A;  4CDD B;  3KW9 A; 
#chains in the Genus database with same CATH homology
 2R6N A;  3OVX A;  4PP2 E;  4Q8G A;  2O6X A;  1ZIV A;  3IV2 A;  2NQG A;  2HXZ A;  1PBH A;  4W5C A;  4NV8 A;  3NHE A;  1YK7 A;  3HD3 A;  3M99 A;  4CDC B;  1SNK A;  1NB5 A;  4X6I A;  1YT7 A;  1F2C A;  2E01 A;  4KLB A;  1F29 A;  5CHT A;  1EWO A;  1BQI A;  5EF4 A;  1PPO A;  1ME4 A;  3BPM A;  3OVZ A;  2IPP B;  3IEJ A;  3N4C A;  2DC8 A;  2DZY A;  3HWN A;  1PPD A;  1DEU A;  1BP4 A;  1GLO A;  5CVM A;  4YYW A;  3H7D A;  3KX1 A;  1MS6 A;  2DZZ A;  2P0R A;  1ME3 A;  3BWK A;  2ACT A;  3K8U A;  4WA6 A;  2AUX A;  3KFQ A;  5EGW A;  2R9O A;  5PAD A;  1W4T A;  4NV7 A;  1U9Q X;  4N8W A;  1XKG A;  4N4Z A;  4MSX A;  3ERV A;  2Y5B A;  4OEL A;  1NLJ A;  1IWD A;  1Y4H A;  4DMX A;  2FYE A;  3KWZ A;  3OF8 A;  2OZ2 A;  2NQI A;  1PCI A;  1NPZ A;  1AU4 A;  1DF0 A;  4AXM A;  2R9N A;  2XU4 A;  4MZS A;  1AYU A;  2FO5 A;  2HH5 A;  1U9X A;  3E1Z B;  3BCN A;  5CHV A;  1QOL A;  4PI3 A;  3P5U A;  2YJ2 A;  9PAP A;  2CB5 A;  2FUD A;  4QRX A;  2JQG R;  2FQ9 A;  1X9Y A;  4X6J A;  5JA7 A;  1QMY A;  2AUZ A;  2BDL A;  1CQD A;  2G8J A;  2VFC A;  2DCA A;  1GMY A;  4K7C A;  1PE6 A;  3PBH A;  2B1M A;  5FPW A;  1AYW A;  2OP3 A;  1MIR A;  2E00 A;  1MHW A;  3MHH A;  4YYV A;  2OUL A;  2BSZ A;  1NL6 A;  1NQC A;  1KFU L;  3H8B A;  3IUT A;  3ZUA A;  4I07 A;  1F2B A;  4BS6 A;  2GFO A;  3PDF A;  3RVV A;  5JH3 A;  1CSB B;  2VHF A;  3C9E A;  3S3R A;  2F7D A;  1U9V A;  3V6C A;  2FRA A;  5CVN B;  1JQP A;  1ZCM A;  1EF7 A;  4P6E A;  1ITO A;  2G6D A;  1STF E;  2AYN A;  2FTD A;  2DCB A;  4BGF A;  2VFB A;  1BY8 A;  4FIP A;  4OEM A;  4Q8H A;  1CS8 A;  3PNR A;  2AIM A;  3PW3 A;  1W5R A;  3KWB X;  4BSQ A;  1KHP A;  4MZO A;  1PAD A;  2HHN A;  1GCB A;  2AVW A;  3D6S A;  4PP1 A;  2R9C A;  1CB5 A;  1KFX L;  4XR7 A;  1EWL A;  3DF0 A;  3IHP A;  4YYU A;  1GEC E;  2PNS A;  1CTE A;  3K9M A;  3HHI A;  2F1G A;  1MDW A;  3P5W A;  2P7U A;  1AU3 A;  1THE A;  4QH6 A;  4ZUX U;  3F75 A;  1AYV A;  3MHS A;  1E2T A;  4P6G A;  1CPJ A;  3N3K A;  2DCD A;  3QJ3 A;  1AEC A;  3N3G A;  3RVW A;  2BDZ A;  4BQV A;  2H7J A;  4AXL A;  2B1N A;  3S3Q A;  1GX3 A;  2DC7 A;  2IBI A;  6PAD A;  1AU2 A;  2XU5 A;  3MOR A;  3MTN A;  1AIM A;  3HHA A;  4HWY A;  1O0E A;  3P5X A;  4I05 A;  4CZW A;  7PCK A;  4DMY A;  3BOW A;  4I04 A;  1TLO A;  1Q6K A;  4C5P A;  5F02 A;  2NQA A;  1A6R A;  4X6H A;  4CDE B;  2AYO A;  3H6S A;  3BPF A;  2ARY A;  1QXP A;  2YJB A;  1M6D A;  5CVO B;  4GUZ A;  8PCH A;  1AU0 A;  1TL9 A;  1MEG A;  3V6E A;  4FK5 A;  3OIS A;  3WXE A;  3CBJ A;  2C0Y A;  2JQF R;  5A24 A;  3O0U A;  1EWP A;  3P5V A;  1PPN A;  3BC3 A;  3GCB A;  3KSE A;  4YYR A;  4G54 A;  2FT2 A;  4YYQ A;  3IOQ A;  3QSD A;  2R9F A;  1VJV A;  4YVA A;  3U8E A;  2DC9 A;  3CH3 X;  1YAL A;  3CBK A;  2PAD A;  1VSN A;  4N79 A;  1F2A A;  3KKU A;  3CH2 X;  4W4U A;  3LFY A;  3IMA A;  2DCC A;  2Y6E A;  2DC6 A;  1NB3 A;  1QDQ A;  1U5I A;  3I06 A;  2VHS A;  3LTW A;  3WXG A;  1SP4 B;  2CIO A;  3I3T A;  5J94 A;  1KXR A;  1W6F A;  2PRE A;  1CJL A;  1PPP A;  1FH0 A;  4YV8 A;  1POP A;  1ICF A;  3K24 A;  2YJ8 A;  3TNX A;  1S4V A;  1MEM A;  3WXF A;  2XU3 A;  1PXV A;  3D9W A;  2PBH A;  4BS5 A;  4CDF B;  1YK8 A;  1Y08 A;  2DJF B;  1CVZ A;  2YJ9 A;  2XU1 A;  4PAD A;  1PIP A;  4RY2 A;  2AU1 A;  1KHQ A;  1BGO A;  3AI8 A;  2G7Y A;  2HD5 A;  4QRG A;  1ATK A;  2NQD B;  2P86 A;  4B55 A;  4BPV A;  2E02 A;  2WBF X;  5K16 A;  3LXS A;  2G8E A;  2R9M A;  3H8C A;  1HUC B;  3F5V A;  2ATO A;  2GHU A;  2YJC A;  2AS8 A;  3H89 A;  1U9W A;  2DJG B;  3OF9 A;  1TU6 A;  3USV A;  4FJC A;  1CV8 A;  3RVX A;  2FRQ A;  4XUI A;  2E03 A;  1YVB A;  1K3B B;  4QRV A;  3QT4 A;  4YYS A;  4QBB A;  4W5B A;  1EWM A;  3B79 A;  3O1G A;  4CDD B;  3KW9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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