2VHSA

Cathsilicatein, a chimera
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
217
structure length
215
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISQKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure and Silica Condensing Activities of Silicatein Alpha-Cathepsin L Chimeras.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CATHSILICATEIN
total genus 66
structure length 215
sequence length 217
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2007-11-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2vhsA00
2XU5A 2P86A 5FPWA 1Y08A 1CTEA 2DCBA 2FYEA 4QBBA 2DJGB 2O6XA 3H8CA 1TU6A 3P5VA 2PNSA 3P5XA 4PADA 1DEUA 5CVMA 3MTNA 3IV2A 2F7DA 1X9YA 3CH2X 3IEJA 2XU1A 2R9OA 4XR7A 1YALA 4BS5A 2H7JA 1PIPA 3K24A 1PBHA 2AUXA 4AXLA 4ZUXU 2AUZA 2AVWA 3S3QA 4N79A 5F02A 2B1NA 2BDZA 1EWMA 9PAPA 1EWPA 1ZCMA 2DCDA 3WXEA 1FH0A 3RVXA 1GCBA 2NQIA 1VJVA 2GFOA 2FUDA 4W4UA 3BWKA 3CH3X 3H89A 4KLBA 1U9WA 1POPA 2JQGR 2ARYA 3BPMA 3PW3A 1GECE 3PNRA 2DC8A 3IHPA 3OISA 4QRVA 1Q6KA 2YJ9A 1KXRA 3I06A 2JQFR 4W5BA 4YYWA 2FO5A 4WA6A 2YJBA 2R9CA 3OF9A 3S3RA 5CHTA 2NQAA 1ME4A 2P0RA 4K7CA 4CDEB 3O1GA 2DCAA 3OVZA 3QJ3A 1AYUA 3KWZA 4XUIA 5EGWA 5EF4A 1DF0A 3OVXA 1PPPA 2VHSA 4I07A 1GLOA 5JH3A 2G7YA 2R9MA 4YVAA 1CQDA 1CB5A 1VSNA 2YJCA 4PI3A 3HHIA 3OF8A 3BC3A 1AIMA 3BCNA 2DCCA 1IWDA 4X6IA 3QSDA 4I05A 2AIMA 1EWOA 1ATKA 3PDFA 1EWLA 2FQ9A 4RY2A 1M6DA 3F75A 8PCHA 1PXVA 3RVVA 2HD5A 1NLJA 3KX1A 1AU2A 2AS8A 4YV8A 4G54A 4N4ZA 4YYQA 2HXZA 1THEA 4X6HA 1KHQA 2Y5BA 1ME3A 1O0EA 3H8BA 4OELA 1F2CA 1SNKA 3WXFA 2AU1A 3N3KA 1U9VA 1HUCB 1GMYA 4BSQA 3QT4A 1BQIA 2R6NA 4N8WA 3LFYA 4DMYA 4X6JA 4P6EA 2E03A 4FK5A 1AYWA 1Y4HA 3P5WA 1TLOA 1PPNA 2DC6A 1ICFA 3IMAA 1AU4A 3H6SA 3KWBX 1NQCA 1STFE 3IUTA 1YK8A 2C0YA 1SP4B 3KW9A 2G8EA 4PP1A 1PADA 4DMXA 5K16A 1XKGA 1CVZA 1MEMA 3HWNA 4BQVA 2FTDA 1MS6A 3MHHA 2E00A 4BS6A 4YYRA 2XU3A 1QOLA 4QH6A 2DC9A 3USVA 3NHEA 2G6DA 3HD3A 2ATOA 4MSXA 3GCBA 5CHVA 1TL9A 2FRQA 4CDCB 1A6RA 1PPOA 2AYNA 4I04A 2G8JA 2P7UA 1KHPA 4CZWA 1U9QX 2IPPB 3PBHA 1CPJA 4CDDB 1BY8A 4HWYA 4YYUA 3IOQA 2NQGA 1AU3A 3KSEA 3CBJA 5J94A 2DJFB 1MEGA 1F2BA 2YJ8A 3P5UA 2ACTA 1KFXL 4QRXA 1EF7A 4PP2E 2FT2A 2R9NA 3K8UA 4YYVA 1KFUL 1QXPA 2WBFX 1NB5A 2OZ2A 3KFQA 3M99A 3O0UA 3H7DA 1ITOA 1F29A 1PPDA 5PADA 2OP3A 2R9FA 3WXGA 3TNXA 1BGOA 3B79A 1PE6A 1S4VA 3I3TA 4W5CA 2AYOA 1NPZA 2E01A 2CIOA 3N4CA 1CJLA 2XU4A 2DZZA 3F5VA 2HH5A 3ZUAA 4MZOA 4YYSA 2BDLA 4AXMA 3AI8A 4P6GA 5CVOB 3K9MA 2F1GA 1CSBB 5CVNB 1CS8A 1AYVA 5A24A 2OULA 7PCKA 4Q8HA 4QRGA 3MORA 3MHSA 4BPVA 2PREA 3RVWA 1QDQA 1AECA 2FRAA 3BOWA 3ERVA 1YT7A 1PCIA 3N3GA 2E02A 1YK7A 1QMYA 4MZSA 1F2AA 3LXSA 2CB5A 2GHUA 3BPFA 1CV8A 3U8EA 5JA7A 1U5IA 2PBHA 1NB3A 1JQPA 1MHWA 4CDFB 4FJCA 1BP4A 3E1ZB 6PADA 2HHNA 3C9EA 2VHFA 1MIRA 1ZIVA 4Q8GA 1K3BB 3KKUA 2PADA 2NQDB 3D6SA 4OEMA 2DC7A 1YVBA 1U9XA 2Y6EA 1MDWA 3CBKA 2YJ2A 3DF0A 1AU0A 3HHAA 4FIPA 2DZYA 1NL6A 2B1MA 3V6CA 3V6EA 2IBIA
chains in the Genus database with same CATH superfamily
2XU5A 4R3DA 2P86A 5FPWA 1Y08A 1CTEA 2DCBA 2FYEA 4QBBA 2DJGB 3B21A 2O6XA 3H8CA 1TU6A 3P5VA 2PNSA 3P5XA 3PHUA 4PADA 1DEUA 5CVMA 3MTNA 4BOZA 3IV2A 2F7DA 2BTWA 1X9YA 4D8BA 5EZSA 3BBAA 3CH2X 3IEJA 2XU1A 2R9OA 4XR7A 1YALA 4BS5A 2H7JA 1PIPA 3BB7A 3K24A 1PBHA 2AUXA 4AXLA 4ZUXU 2AUZA 2AVWA 2BTWB 4N79A 5F02A 3S3QA 2B1NA 2BDZA 1EWMA 9PAPA 1EWPA 1ZCMA 2DCDA 3WXEA 1FH0A 3RVXA 1GCBA 2FE8A 2NQIA 1VJVA 2GFOA 2FUDA 4D8IA 4W4UA 3BWKA 3CH3X 3H89A 4KLBA 4A5UA 1U9WA 1POPA 2JQGR 2ARYA 3BPMA 3PW3A 3PRMA 1GECE 3PNRA 2DC8A 3IHPA 3OISA 4QRVA 1Q6KA 2YJ9A 1KXRA 3I06A 2JQFR 4W5BA 4YYWA 2FO5A 4WA6A 2Z84A 2YJBA 3TRKA 2R9CA 3OF9A 3S3RA 5CHTA 3ZNHA 2NQAA 1ME4A 2P0RA 4K7CA 4CDEB 3O1GA 5EZQA 2DCAA 3OVZA 3QJ3A 1AYUA 3KWZA 4XUIA 5EGWA 5EF4A 1DF0A 3OVXA 1PPPA 2VHSA 4I07A 1GLOA 5JH3A 2G7YA 2R9MA 4YVAA 1CQDA 1CB5A 1VSNA 3E9SA 2YJCA 4PI3A 3HHIA 3OF8A 3BC3A 1AIMA 3BCNA 3PT2A 2DCCA 1IWDA 4X6IA 3QSDA 4I05A 4OVZA 2DOSA 2AIMA 1EWOA 1ATKA 3MTVA 3PDFA 1EWLA 2FQ9A 4RY2A 1M6DA 3F75A 2UZJA 4RF0A 8PCHA 1PXVA 4IP3A 3RVVA 2HD5A 1NLJA 4HXDB 1DKIA 3KX1A 1AU2A 1UKFA 2AS8A 3W31A 4YV8A 4G54A 4N4ZA 3W30A 4YYQA 4OVZB 2HXZA 4BOSA 1THEA 4X6HA 1KHQA 2Y5BA 1ME3A 1O0EA 3H8BA 1F2CA 1SNKA 4OELA 3WXFA 2AU1A 3N3KA 1U9VA 1HUCB 1GMYA 4BSQA 3QT4A 3OQCA 1BQIA 2R6NA 4N8WA 5E6JA 3LFYA 4DMYA 4X6JA 4BOPA 4P6EA 2E03A 4FK5A 1AYWA 1Y4HA 3P5WA 1TLOA 1PPNA 2DC6A 1ICFA 3IMAA 1AU4A 3H6SA 3KWBX 3MJ5A 1NQCA 1STFE 3IUTA 1YK8A 2C0YA 1SP4B 3KW9A 2G8EA 4PP1A 1PADA 4DMXA 4MI7A 5K16A 4GUAA 1XKGA 1CVZA 1MEMA 3HWNA 4BQVA 2FTDA 1MS6A 3MHHA 2E00A 4BS6A 4YYRA 2XU3A 1QOLA 4QH6A 2DC9A 3USVA 3NHEA 2G6DA 2BU3A 3HD3A 2ATOA 4MSXA 3GCBA 5CHVA 1TL9A 2FRQA 2J7QA 4CDCB 1A6RA 1PPOA 2AYNA 4I04A 2G8JA 2P7UA 1KHPA 4BOQA 4CZWA 1U9QX 2IPPB 3PBHA 1CPJA 4CDDB 1BY8A 4HWYA 2J7QC 4YYUA 3IOQA 2NQGA 1AU3A 3KSEA 3CBJA 5J94A 2DJFB 1MEGA 4RKXA 5KO3A 1F2BA 2YJ8A 3P5UA 2ACTA 1KFXL 4QRXA 1EF7A 3TMPA 4PP2E 2FT2A 2R9NA 3K8UA 4YYVA 1KFUL 1QXPA 2WBFX 1NB5A 2OZ2A 3KFQA 3M99A 3O0UA 3H7DA 1ITOA 1F29A 1PPDA 5PADA 2OP3A 2R9FA 3WXGA 3TNXA 1BGOA 3B79A 1PE6A 1S4VA 3I3TA 4W5CA 4M0WA 4D8EA 2AYOA 5JZEA 2HWKA 1NPZA 2E01A 2CIOA 3N4CA 4REZA 1CJLA 2XU4A 2DZZA 3F5VA 2HH5A 4BOUA 3ZUAA 4MZOA 4YYSA 2BDLA 4AXMA 3AI8A 4P6GA 5CVOB 3K9MA 2F1GA 1CSBB 5CVNB 1CS8A 1AYVA 5A24A 3MP2A 2OULA 3PSEA 7PCKA 4Q8HA 4QRGA 3MORA 2JRIA 3PHXA 3MHSA 4BPVA 2PREA 3RVWA 4ZTBA 1QDQA 1AECA 2FRAA 3BOWA 3ERVA 3C0RA 3N3GA 1PCIA 1YT7A 2E02A 2AGAA 1YK7A 1QMYA 4MZSA 1F2AA 3LXSA 2CB5A 2GHUA 3BPFA 1CV8A 3U8EA 4XZXA 3BY4A 5JA7A 1U5IA 2PBHA 1NB3A 1JQPA 1MHWA 4RF1A 4CDFB 4FJCA 1BP4A 3E1ZB 6PADA 2HHNA 3C9EA 2VHFA 3PRPA 4MM3B 1MIRA 4PT5A 4OW0A 4P16A 1ZIVA 4Q8GA 1K3BB 3KKUA 2PADA 2NQDB 3D6SA 4OEMA 4IUMA 2DC7A 1YVBA 1U9XA 2Y6EA 1MDWA 2JTCA 3CBKA 2YJ2A 3DF0A 3O65A 1AU0A 3RNVA 3PHWA 4WURA 3IFUA 1PVJA 3HHAA 4FIPA 4RNAA 2DZYA 1NL6A 2B1MA 3V6CA 3V6EA 1YZBA 2IBIA
chains in the Genus database with same CATH topology
2XU5A 2P86A 5FPWA 1Y08A 1CTEA 2DCBA 2FYEA 4QBBA 4B55A 2DJGB 4GUZA 2O6XA 3H8CA 1TU6A 3P5VA 2PNSA 3P5XA 4PADA 1DEUA 5CVMA 3MTNA 3IV2A 2F7DA 2BSZA 1X9YA 1E2TA 3CH2X 3IEJA 2XU1A 2R9OA 4XR7A 1YALA 4BS5A 2H7JA 1PIPA 3LTWA 3K24A 1PBHA 2AUXA 4AXLA 4ZUXU 2AUZA 2AVWA 3S3QA 4N79A 5F02A 2B1NA 2BDZA 1EWMA 9PAPA 1EWPA 1ZCMA 2DCDA 3WXEA 2VFCA 1FH0A 3RVXA 1GCBA 2NQIA 1VJVA 2GFOA 2FUDA 4W4UA 3BWKA 3CH3X 3H89A 4KLBA 1U9WA 1POPA 2JQGR 2ARYA 3BPMA 3PW3A 1GECE 3PNRA 2DC8A 3IHPA 3OISA 4QRVA 1Q6KA 2YJ9A 1KXRA 3I06A 2JQFR 4W5BA 4YYWA 2FO5A 4WA6A 2YJBA 2R9CA 3OF9A 3S3RA 5CHTA 2NQAA 1ME4A 2P0RA 4K7CA 4CDEB 3O1GA 2DCAA 3OVZA 3QJ3A 1AYUA 3KWZA 4XUIA 5EGWA 1W5RA 5EF4A 1DF0A 3OVXA 4C5PA 1PPPA 2VHSA 4I07A 1GLOA 5JH3A 2G7YA 2R9MA 4YVAA 1CQDA 1CB5A 1VSNA 2YJCA 4PI3A 3HHIA 3OF8A 3BC3A 1AIMA 3BCNA 2DCCA 1IWDA 4X6IA 3QSDA 4I05A 2AIMA 1EWOA 1ATKA 3PDFA 1EWLA 2FQ9A 4RY2A 1M6DA 3F75A 8PCHA 1PXVA 3RVVA 2HD5A 1NLJA 3KX1A 1AU2A 2AS8A 4YV8A 4G54A 4N4ZA 4YYQA 2HXZA 1THEA 4X6HA 1KHQA 2Y5BA 1ME3A 1O0EA 3H8BA 1F2CA 1SNKA 4OELA 3WXFA 2AU1A 3N3KA 1U9VA 1HUCB 1GMYA 4BSQA 3QT4A 1BQIA 2R6NA 4N8WA 1W4TA 3LFYA 4DMYA 4X6JA 4P6EA 2E03A 4FK5A 1AYWA 1Y4HA 3P5WA 1TLOA 1PPNA 2DC6A 1ICFA 3IMAA 1AU4A 3H6SA 3KWBX 1NQCA 1STFE 3IUTA 1YK8A 2C0YA 1SP4B 3KW9A 2G8EA 4PP1A 1PADA 4DMXA 5K16A 1XKGA 1CVZA 1MEMA 1W6FA 3HWNA 4BQVA 2FTDA 1MS6A 3MHHA 4NV7A 2E00A 4BS6A 4YYRA 2XU3A 1QOLA 4QH6A 2DC9A 3USVA 3NHEA 2G6DA 3HD3A 4BGFA 2ATOA 4MSXA 3GCBA 5CHVA 1TL9A 2FRQA 4CDCB 1A6RA 1PPOA 2AYNA 4I04A 2G8JA 2P7UA 1KHPA 4CZWA 1U9QX 2IPPB 3PBHA 1CPJA 4CDDB 1BY8A 4HWYA 4YYUA 3IOQA 2NQGA 1AU3A 3KSEA 3CBJA 5J94A 2DJFB 1MEGA 1F2BA 2YJ8A 3P5UA 2ACTA 1KFXL 4QRXA 1EF7A 4PP2E 2FT2A 2R9NA 3K8UA 4YYVA 1KFUL 1QXPA 2WBFX 1NB5A 2OZ2A 3KFQA 3M99A 3O0UA 3H7DA 3D9WA 1ITOA 1F29A 1PPDA 5PADA 2OP3A 2R9FA 3WXGA 3TNXA 1BGOA 3B79A 1PE6A 1S4VA 3I3TA 4W5CA 2AYOA 1NPZA 2E01A 2CIOA 3N4CA 4NV8A 1CJLA 2XU4A 2DZZA 3F5VA 2HH5A 1GX3A 4MZOA 3ZUAA 4YYSA 2BDLA 4AXMA 3AI8A 4P6GA 5CVOB 3K9MA 2F1GA 1CSBB 5CVNB 1CS8A 1AYVA 5A24A 2OULA 7PCKA 4Q8HA 4QRGA 3MORA 3MHSA 4BPVA 2PREA 3RVWA 1QDQA 1AECA 2FRAA 3BOWA 3ERVA 3N3GA 1PCIA 1YT7A 2E02A 2IBIA 1YK7A 1QMYA 4MZSA 1F2AA 3LXSA 2CB5A 2GHUA 3BPFA 1CV8A 3U8EA 5JA7A 1U5IA 2PBHA 1NB3A 1JQPA 1MHWA 4CDFB 4FJCA 1BP4A 3E1ZB 6PADA 2HHNA 3C9EA 2VHFA 1MIRA 1ZIVA 4Q8GA 1K3BB 3KKUA 2PADA 2NQDB 3D6SA 4OEMA 2DC7A 1YVBA 1U9XA 2Y6EA 1MDWA 3CBKA 2YJ2A 3DF0A 1AU0A 3HHAA 4FIPA 2DZYA 1NL6A 2B1MA 3V6CA 3V6EA 2VFBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XU5 A;  2P86 A;  5FPW A;  1Y08 A;  1CTE A;  2DCB A;  2FYE A;  4QBB A;  2DJG B;  2O6X A;  3H8C A;  1TU6 A;  3P5V A;  2PNS A;  3P5X A;  4PAD A;  1DEU A;  5CVM A;  3MTN A;  3IV2 A;  2F7D A;  1X9Y A;  3CH2 X;  3IEJ A;  2XU1 A;  2R9O A;  4XR7 A;  1YAL A;  4BS5 A;  2H7J A;  1PIP A;  3K24 A;  1PBH A;  2AUX A;  4AXL A;  4ZUX U;  2AUZ A;  2AVW A;  3S3Q A;  4N79 A;  5F02 A;  2B1N A;  2BDZ A;  1EWM A;  9PAP A;  1EWP A;  1ZCM A;  2DCD A;  3WXE A;  1FH0 A;  3RVX A;  1GCB A;  2NQI A;  1VJV A;  2GFO A;  2FUD A;  4W4U A;  3BWK A;  3CH3 X;  3H89 A;  4KLB A;  1U9W A;  1POP A;  2JQG R;  2ARY A;  3BPM A;  3PW3 A;  1GEC E;  3PNR A;  2DC8 A;  3IHP A;  3OIS A;  4QRV A;  1Q6K A;  2YJ9 A;  1KXR A;  3I06 A;  2JQF R;  4W5B A;  4YYW A;  2FO5 A;  4WA6 A;  2YJB A;  2R9C A;  3OF9 A;  3S3R A;  5CHT A;  2NQA A;  1ME4 A;  2P0R A;  4K7C A;  4CDE B;  3O1G A;  2DCA A;  3OVZ A;  3QJ3 A;  1AYU A;  3KWZ A;  4XUI A;  5EGW A;  5EF4 A;  1DF0 A;  3OVX A;  1PPP A;  2VHS A;  4I07 A;  1GLO A;  5JH3 A;  2G7Y A;  2R9M A;  4YVA A;  1CQD A;  1CB5 A;  1VSN A;  2YJC A;  4PI3 A;  3HHI A;  3OF8 A;  3BC3 A;  1AIM A;  3BCN A;  2DCC A;  1IWD A;  4X6I A;  3QSD A;  4I05 A;  2AIM A;  1EWO A;  1ATK A;  3PDF A;  1EWL A;  2FQ9 A;  4RY2 A;  1M6D A;  3F75 A;  8PCH A;  1PXV A;  3RVV A;  2HD5 A;  1NLJ A;  3KX1 A;  1AU2 A;  2AS8 A;  4YV8 A;  4G54 A;  4N4Z A;  4YYQ A;  2HXZ A;  1THE A;  4X6H A;  1KHQ A;  2Y5B A;  1ME3 A;  1O0E A;  3H8B A;  4OEL A;  1F2C A;  1SNK A;  3WXF A;  2AU1 A;  3N3K A;  1U9V A;  1HUC B;  1GMY A;  4BSQ A;  3QT4 A;  1BQI A;  2R6N A;  4N8W A;  3LFY A;  4DMY A;  4X6J A;  4P6E A;  2E03 A;  4FK5 A;  1AYW A;  1Y4H A;  3P5W A;  1TLO A;  1PPN A;  2DC6 A;  1ICF A;  3IMA A;  1AU4 A;  3H6S A;  3KWB X;  1NQC A;  1STF E;  3IUT A;  1YK8 A;  2C0Y A;  1SP4 B;  3KW9 A;  2G8E A;  4PP1 A;  1PAD A;  4DMX A;  5K16 A;  1XKG A;  1CVZ A;  1MEM A;  3HWN A;  4BQV A;  2FTD A;  1MS6 A;  3MHH A;  2E00 A;  4BS6 A;  4YYR A;  2XU3 A;  1QOL A;  4QH6 A;  2DC9 A;  3USV A;  3NHE A;  2G6D A;  3HD3 A;  2ATO A;  4MSX A;  3GCB A;  5CHV A;  1TL9 A;  2FRQ A;  4CDC B;  1A6R A;  1PPO A;  2AYN A;  4I04 A;  2G8J A;  2P7U A;  1KHP A;  4CZW A;  1U9Q X;  2IPP B;  3PBH A;  1CPJ A;  4CDD B;  1BY8 A;  4HWY A;  4YYU A;  3IOQ A;  2NQG A;  1AU3 A;  3KSE A;  3CBJ A;  5J94 A;  2DJF B;  1MEG A;  1F2B A;  2YJ8 A;  3P5U A;  2ACT A;  1KFX L;  4QRX A;  1EF7 A;  4PP2 E;  2FT2 A;  2R9N A;  3K8U A;  4YYV A;  1KFU L;  1QXP A;  2WBF X;  1NB5 A;  2OZ2 A;  3KFQ A;  3M99 A;  3O0U A;  3H7D A;  1ITO A;  1F29 A;  1PPD A;  5PAD A;  2OP3 A;  2R9F A;  3WXG A;  3TNX A;  1BGO A;  3B79 A;  1PE6 A;  1S4V A;  3I3T A;  4W5C A;  2AYO A;  1NPZ A;  2E01 A;  2CIO A;  3N4C A;  1CJL A;  2XU4 A;  2DZZ A;  3F5V A;  2HH5 A;  3ZUA A;  4MZO A;  4YYS A;  2BDL A;  4AXM A;  3AI8 A;  4P6G A;  5CVO B;  3K9M A;  2F1G A;  1CSB B;  5CVN B;  1CS8 A;  1AYV A;  5A24 A;  2OUL A;  7PCK A;  4Q8H A;  4QRG A;  3MOR A;  3MHS A;  4BPV A;  2PRE A;  3RVW A;  1QDQ A;  1AEC A;  2FRA A;  3BOW A;  3ERV A;  1YT7 A;  1PCI A;  3N3G A;  2E02 A;  1YK7 A;  1QMY A;  4MZS A;  1F2A A;  3LXS A;  2CB5 A;  2GHU A;  3BPF A;  1CV8 A;  3U8E A;  5JA7 A;  1U5I A;  2PBH A;  1NB3 A;  1JQP A;  1MHW A;  4CDF B;  4FJC A;  1BP4 A;  3E1Z B;  6PAD A;  2HHN A;  3C9E A;  2VHF A;  1MIR A;  1ZIV A;  4Q8G A;  1K3B B;  3KKU A;  2PAD A;  2NQD B;  3D6S A;  4OEM A;  2DC7 A;  1YVB A;  1U9X A;  2Y6E A;  1MDW A;  3CBK A;  2YJ2 A;  3DF0 A;  1AU0 A;  3HHA A;  4FIP A;  2DZY A;  1NL6 A;  2B1M A;  3V6C A;  3V6E A;  2IBI A; 
#chains in the Genus database with same CATH topology
 2XU5 A;  4R3D A;  2P86 A;  5FPW A;  1Y08 A;  1CTE A;  2DCB A;  2FYE A;  4QBB A;  2DJG B;  3B21 A;  2O6X A;  3H8C A;  1TU6 A;  3P5V A;  2PNS A;  3P5X A;  3PHU A;  4PAD A;  1DEU A;  5CVM A;  3MTN A;  4BOZ A;  3IV2 A;  2F7D A;  2BTW A;  1X9Y A;  4D8B A;  5EZS A;  3BBA A;  3CH2 X;  3IEJ A;  2XU1 A;  2R9O A;  4XR7 A;  1YAL A;  4BS5 A;  2H7J A;  1PIP A;  3BB7 A;  3K24 A;  1PBH A;  2AUX A;  4AXL A;  4ZUX U;  2AUZ A;  2AVW A;  2BTW B;  4N79 A;  5F02 A;  3S3Q A;  2B1N A;  2BDZ A;  1EWM A;  9PAP A;  1EWP A;  1ZCM A;  2DCD A;  3WXE A;  1FH0 A;  3RVX A;  1GCB A;  2FE8 A;  2NQI A;  1VJV A;  2GFO A;  2FUD A;  4D8I A;  4W4U A;  3BWK A;  3CH3 X;  3H89 A;  4KLB A;  4A5U A;  1U9W A;  1POP A;  2JQG R;  2ARY A;  3BPM A;  3PW3 A;  3PRM A;  1GEC E;  3PNR A;  2DC8 A;  3IHP A;  3OIS A;  4QRV A;  1Q6K A;  2YJ9 A;  1KXR A;  3I06 A;  2JQF R;  4W5B A;  4YYW A;  2FO5 A;  4WA6 A;  2Z84 A;  2YJB A;  3TRK A;  2R9C A;  3OF9 A;  3S3R A;  5CHT A;  3ZNH A;  2NQA A;  1ME4 A;  2P0R A;  4K7C A;  4CDE B;  3O1G A;  5EZQ A;  2DCA A;  3OVZ A;  3QJ3 A;  1AYU A;  3KWZ A;  4XUI A;  5EGW A;  5EF4 A;  1DF0 A;  3OVX A;  1PPP A;  2VHS A;  4I07 A;  1GLO A;  5JH3 A;  2G7Y A;  2R9M A;  4YVA A;  1CQD A;  1CB5 A;  1VSN A;  3E9S A;  2YJC A;  4PI3 A;  3HHI A;  3OF8 A;  3BC3 A;  1AIM A;  3BCN A;  3PT2 A;  2DCC A;  1IWD A;  4X6I A;  3QSD A;  4I05 A;  4OVZ A;  2DOS A;  2AIM A;  1EWO A;  1ATK A;  3MTV A;  3PDF A;  1EWL A;  2FQ9 A;  4RY2 A;  1M6D A;  3F75 A;  2UZJ A;  4RF0 A;  8PCH A;  1PXV A;  4IP3 A;  3RVV A;  2HD5 A;  1NLJ A;  4HXD B;  1DKI A;  3KX1 A;  1AU2 A;  1UKF A;  2AS8 A;  3W31 A;  4YV8 A;  4G54 A;  4N4Z A;  3W30 A;  4YYQ A;  4OVZ B;  2HXZ A;  4BOS A;  1THE A;  4X6H A;  1KHQ A;  2Y5B A;  1ME3 A;  1O0E A;  3H8B A;  1F2C A;  1SNK A;  4OEL A;  3WXF A;  2AU1 A;  3N3K A;  1U9V A;  1HUC B;  1GMY A;  4BSQ A;  3QT4 A;  3OQC A;  1BQI A;  2R6N A;  4N8W A;  5E6J A;  3LFY A;  4DMY A;  4X6J A;  4BOP A;  4P6E A;  2E03 A;  4FK5 A;  1AYW A;  1Y4H A;  3P5W A;  1TLO A;  1PPN A;  2DC6 A;  1ICF A;  3IMA A;  1AU4 A;  3H6S A;  3KWB X;  3MJ5 A;  1NQC A;  1STF E;  3IUT A;  1YK8 A;  2C0Y A;  1SP4 B;  3KW9 A;  2G8E A;  4PP1 A;  1PAD A;  4DMX A;  4MI7 A;  5K16 A;  4GUA A;  1XKG A;  1CVZ A;  1MEM A;  3HWN A;  4BQV A;  2FTD A;  1MS6 A;  3MHH A;  2E00 A;  4BS6 A;  4YYR A;  2XU3 A;  1QOL A;  4QH6 A;  2DC9 A;  3USV A;  3NHE A;  2G6D A;  2BU3 A;  3HD3 A;  2ATO A;  4MSX A;  3GCB A;  5CHV A;  1TL9 A;  2FRQ A;  2J7Q A;  4CDC B;  1A6R A;  1PPO A;  2AYN A;  4I04 A;  2G8J A;  2P7U A;  1KHP A;  4BOQ A;  4CZW A;  1U9Q X;  2IPP B;  3PBH A;  1CPJ A;  4CDD B;  1BY8 A;  4HWY A;  2J7Q C;  4YYU A;  3IOQ A;  2NQG A;  1AU3 A;  3KSE A;  3CBJ A;  5J94 A;  2DJF B;  1MEG A;  4RKX A;  5KO3 A;  1F2B A;  2YJ8 A;  3P5U A;  2ACT A;  1KFX L;  4QRX A;  1EF7 A;  3TMP A;  4PP2 E;  2FT2 A;  2R9N A;  3K8U A;  4YYV A;  1KFU L;  1QXP A;  2WBF X;  1NB5 A;  2OZ2 A;  3KFQ A;  3M99 A;  3O0U A;  3H7D A;  1ITO A;  1F29 A;  1PPD A;  5PAD A;  2OP3 A;  2R9F A;  3WXG A;  3TNX A;  1BGO A;  3B79 A;  1PE6 A;  1S4V A;  3I3T A;  4W5C A;  4M0W A;  4D8E A;  2AYO A;  5JZE A;  2HWK A;  1NPZ A;  2E01 A;  2CIO A;  3N4C A;  4REZ A;  1CJL A;  2XU4 A;  2DZZ A;  3F5V A;  2HH5 A;  4BOU A;  3ZUA A;  4MZO A;  4YYS A;  2BDL A;  4AXM A;  3AI8 A;  4P6G A;  5CVO B;  3K9M A;  2F1G A;  1CSB B;  5CVN B;  1CS8 A;  1AYV A;  5A24 A;  3MP2 A;  2OUL A;  3PSE A;  7PCK A;  4Q8H A;  4QRG A;  3MOR A;  2JRI A;  3PHX A;  3MHS A;  4BPV A;  2PRE A;  3RVW A;  4ZTB A;  1QDQ A;  1AEC A;  2FRA A;  3BOW A;  3ERV A;  3C0R A;  3N3G A;  1PCI A;  1YT7 A;  2E02 A;  2AGA A;  1YK7 A;  1QMY A;  4MZS A;  1F2A A;  3LXS A;  2CB5 A;  2GHU A;  3BPF A;  1CV8 A;  3U8E A;  4XZX A;  3BY4 A;  5JA7 A;  1U5I A;  2PBH A;  1NB3 A;  1JQP A;  1MHW A;  4RF1 A;  4CDF B;  4FJC A;  1BP4 A;  3E1Z B;  6PAD A;  2HHN A;  3C9E A;  2VHF A;  3PRP A;  4MM3 B;  1MIR A;  4PT5 A;  4OW0 A;  4P16 A;  1ZIV A;  4Q8G A;  1K3B B;  3KKU A;  2PAD A;  2NQD B;  3D6S A;  4OEM A;  4IUM A;  2DC7 A;  1YVB A;  1U9X A;  2Y6E A;  1MDW A;  2JTC A;  3CBK A;  2YJ2 A;  3DF0 A;  3O65 A;  1AU0 A;  3RNV A;  3PHW A;  4WUR A;  3IFU A;  1PVJ A;  3HHA A;  4FIP A;  4RNA A;  2DZY A;  1NL6 A;  2B1M A;  3V6C A;  3V6E A;  1YZB A;  2IBI A; 
#chains in the Genus database with same CATH homology
 2XU5 A;  2P86 A;  5FPW A;  1Y08 A;  1CTE A;  2DCB A;  2FYE A;  4QBB A;  4B55 A;  2DJG B;  4GUZ A;  2O6X A;  3H8C A;  1TU6 A;  3P5V A;  2PNS A;  3P5X A;  4PAD A;  1DEU A;  5CVM A;  3MTN A;  3IV2 A;  2F7D A;  2BSZ A;  1X9Y A;  1E2T A;  3CH2 X;  3IEJ A;  2XU1 A;  2R9O A;  4XR7 A;  1YAL A;  4BS5 A;  2H7J A;  1PIP A;  3LTW A;  3K24 A;  1PBH A;  2AUX A;  4AXL A;  4ZUX U;  2AUZ A;  2AVW A;  3S3Q A;  4N79 A;  5F02 A;  2B1N A;  2BDZ A;  1EWM A;  9PAP A;  1EWP A;  1ZCM A;  2DCD A;  3WXE A;  2VFC A;  1FH0 A;  3RVX A;  1GCB A;  2NQI A;  1VJV A;  2GFO A;  2FUD A;  4W4U A;  3BWK A;  3CH3 X;  3H89 A;  4KLB A;  1U9W A;  1POP A;  2JQG R;  2ARY A;  3BPM A;  3PW3 A;  1GEC E;  3PNR A;  2DC8 A;  3IHP A;  3OIS A;  4QRV A;  1Q6K A;  2YJ9 A;  1KXR A;  3I06 A;  2JQF R;  4W5B A;  4YYW A;  2FO5 A;  4WA6 A;  2YJB A;  2R9C A;  3OF9 A;  3S3R A;  5CHT A;  2NQA A;  1ME4 A;  2P0R A;  4K7C A;  4CDE B;  3O1G A;  2DCA A;  3OVZ A;  3QJ3 A;  1AYU A;  3KWZ A;  4XUI A;  5EGW A;  1W5R A;  5EF4 A;  1DF0 A;  3OVX A;  4C5P A;  1PPP A;  2VHS A;  4I07 A;  1GLO A;  5JH3 A;  2G7Y A;  2R9M A;  4YVA A;  1CQD A;  1CB5 A;  1VSN A;  2YJC A;  4PI3 A;  3HHI A;  3OF8 A;  3BC3 A;  1AIM A;  3BCN A;  2DCC A;  1IWD A;  4X6I A;  3QSD A;  4I05 A;  2AIM A;  1EWO A;  1ATK A;  3PDF A;  1EWL A;  2FQ9 A;  4RY2 A;  1M6D A;  3F75 A;  8PCH A;  1PXV A;  3RVV A;  2HD5 A;  1NLJ A;  3KX1 A;  1AU2 A;  2AS8 A;  4YV8 A;  4G54 A;  4N4Z A;  4YYQ A;  2HXZ A;  1THE A;  4X6H A;  1KHQ A;  2Y5B A;  1ME3 A;  1O0E A;  3H8B A;  1F2C A;  1SNK A;  4OEL A;  3WXF A;  2AU1 A;  3N3K A;  1U9V A;  1HUC B;  1GMY A;  4BSQ A;  3QT4 A;  1BQI A;  2R6N A;  4N8W A;  1W4T A;  3LFY A;  4DMY A;  4X6J A;  4P6E A;  2E03 A;  4FK5 A;  1AYW A;  1Y4H A;  3P5W A;  1TLO A;  1PPN A;  2DC6 A;  1ICF A;  3IMA A;  1AU4 A;  3H6S A;  3KWB X;  1NQC A;  1STF E;  3IUT A;  1YK8 A;  2C0Y A;  1SP4 B;  3KW9 A;  2G8E A;  4PP1 A;  1PAD A;  4DMX A;  5K16 A;  1XKG A;  1CVZ A;  1MEM A;  1W6F A;  3HWN A;  4BQV A;  2FTD A;  1MS6 A;  3MHH A;  4NV7 A;  2E00 A;  4BS6 A;  4YYR A;  2XU3 A;  1QOL A;  4QH6 A;  2DC9 A;  3USV A;  3NHE A;  2G6D A;  3HD3 A;  4BGF A;  2ATO A;  4MSX A;  3GCB A;  5CHV A;  1TL9 A;  2FRQ A;  4CDC B;  1A6R A;  1PPO A;  2AYN A;  4I04 A;  2G8J A;  2P7U A;  1KHP A;  4CZW A;  1U9Q X;  2IPP B;  3PBH A;  1CPJ A;  4CDD B;  1BY8 A;  4HWY A;  4YYU A;  3IOQ A;  2NQG A;  1AU3 A;  3KSE A;  3CBJ A;  5J94 A;  2DJF B;  1MEG A;  1F2B A;  2YJ8 A;  3P5U A;  2ACT A;  1KFX L;  4QRX A;  1EF7 A;  4PP2 E;  2FT2 A;  2R9N A;  3K8U A;  4YYV A;  1KFU L;  1QXP A;  2WBF X;  1NB5 A;  2OZ2 A;  3KFQ A;  3M99 A;  3O0U A;  3H7D A;  3D9W A;  1ITO A;  1F29 A;  1PPD A;  5PAD A;  2OP3 A;  2R9F A;  3WXG A;  3TNX A;  1BGO A;  3B79 A;  1PE6 A;  1S4V A;  3I3T A;  4W5C A;  2AYO A;  1NPZ A;  2E01 A;  2CIO A;  3N4C A;  4NV8 A;  1CJL A;  2XU4 A;  2DZZ A;  3F5V A;  2HH5 A;  1GX3 A;  4MZO A;  3ZUA A;  4YYS A;  2BDL A;  4AXM A;  3AI8 A;  4P6G A;  5CVO B;  3K9M A;  2F1G A;  1CSB B;  5CVN B;  1CS8 A;  1AYV A;  5A24 A;  2OUL A;  7PCK A;  4Q8H A;  4QRG A;  3MOR A;  3MHS A;  4BPV A;  2PRE A;  3RVW A;  1QDQ A;  1AEC A;  2FRA A;  3BOW A;  3ERV A;  3N3G A;  1PCI A;  1YT7 A;  2E02 A;  2IBI A;  1YK7 A;  1QMY A;  4MZS A;  1F2A A;  3LXS A;  2CB5 A;  2GHU A;  3BPF A;  1CV8 A;  3U8E A;  5JA7 A;  1U5I A;  2PBH A;  1NB3 A;  1JQP A;  1MHW A;  4CDF B;  4FJC A;  1BP4 A;  3E1Z B;  6PAD A;  2HHN A;  3C9E A;  2VHF A;  1MIR A;  1ZIV A;  4Q8G A;  1K3B B;  3KKU A;  2PAD A;  2NQD B;  3D6S A;  4OEM A;  2DC7 A;  1YVB A;  1U9X A;  2Y6E A;  1MDW A;  3CBK A;  2YJ2 A;  3DF0 A;  1AU0 A;  3HHA A;  4FIP A;  2DZY A;  1NL6 A;  2B1M A;  3V6C A;  3V6E A;  2VFB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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