2ARYA

Catalytic domain of human calpain-1
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Calpain-1 catalytic subunit
total genus 89
structure length 322
sequence length 322
chains with identical sequence B
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2005-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2aryA02
1BQIA 1AU4A 4W5BA 4YVAA 1CQDA 3PNRA 2DC9A 2FRAA 2R9CA 2AYNA 3MHHA 3P5UA 5J94A 2R9NA 2GHUA 3MORA 1ZIVA 3IEJA 5F02A 2FQ9A 2XU1A 3NHEA 3OF9A 2BDZA 1BGOA 4OEMA 1PADA 1MDWA 4P6GA 4QRGA 3BCNA 4AXLA 1CV8A 2P7UA 4DMXA 2G8JA 3LFYA 1DF0A 1GMYA 2IBIA 3IV2A 1NQCA 1ITOA 5CVNB 3S3RA 1U9VA 3CH2X 3BPFA 3TNXA 1F2BA 2AUXA 2JQFR 3MHSA 3N3KA 5JH3A 2FUDA 1TL9A 2DC8A 4CDCB 1YK7A 2ARYA 1CJLA 3B79A 3IUTA 4OELA 3QT4A 4PI3A 2DCDA 3H6SA 1YT7A 1BY8A 3GCBA 1EWLA 2Y5BA 2PNSA 3F5VA 2B1NA 1KXRA 3HD3A 4K7CA 1AU0A 4YV8A 1CS8A 4N4ZA 1MIRA 3M99A 4I05A 4CDDB 2AS8A 2YJCA 1PXVA 4YYQA 2FTDA 1HUCB 1PIPA 1SP4B 2AVWA 2G7YA 1GCBA 1THEA 3CBJA 1AYWA 1F2CA 4PP1A 3IMAA 4X6IA 3K24A 2O6XA 2B1MA 2YJ9A 1Q6KA 4QRXA 3OVZA 5A24A 2NQAA 4W4UA 2CIOA 3K8UA 4YYRA 1CTEA 3O1GA 8PCHA 1QDQA 2AIMA 2H7JA 3LXSA 4N79A 1QMYA 4G54A 1Y4HA 2DJGB 1QOLA 1GLOA 2Y6EA 7PCKA 3PDFA 1EF7A 2NQIA 4HWYA 2R6NA 3BC3A 1U9XA 2FO5A 1SNKA 4BSQA 3KWBX 2FRQA 3F75A 3KFQA 1CSBB 3CBKA 1AECA 3S3QA 2XU4A 3HHAA 4YYVA 3PBHA 1STFE 1ATKA 4CDFB 1NB5A 1MS6A 2DC7A 4BS5A 2YJ8A 1NLJA 2HH5A 4FIPA 2AU1A 1KFUL 3K9MA 2DZYA 2DCCA 3KKUA 3USVA 3QJ3A 2DJFB 4BPVA 1PPDA 1YVBA 2AYOA 2VHSA 3DF0A 3WXGA 2OP3A 2GFOA 3KSEA 1QXPA 2R9FA 2YJBA 1A6RA 2PADA 3RVVA 5JA7A 4ZUXU 1EWOA 3IOQA 1M6DA 3ZUAA 1IWDA 1PCIA 2BDLA 1FH0A 6PADA 4MSXA 1BP4A 1O0EA 1ZCMA 1KHQA 3OISA 2HHNA 3N4CA 1PE6A 1U9WA 2FT2A 2ACTA 2E03A 3H7DA 4BS6A 4PADA 5EGWA 2NQDB 2PREA 3HHIA 4I07A 2E00A 5CHVA 4YYUA 1ME4A 2JQGR 5K16A 2CB5A 2E02A 4DMYA 5CHTA 2AUZA 3CH3X 3MTNA 2G6DA 3N3GA 3AI8A 1PPNA 2YJ2A 1F29A 2P86A 1NL6A 3U8EA 4XUIA 2WBFX 1NPZA 3BPMA 5CVOB 3PW3A 1VSNA 1Y08A 2C0YA 2OZ2A 5CVMA 2DCAA 3H89A 1EWMA 3H8BA 2E01A 1CPJA 1MEMA 3WXEA 1MEGA 4P6EA 3KW9A 1POPA 1AIMA 1PBHA 3E1ZB 1U5IA 4N8WA 2XU3A 3D6SA 4I04A 1U9QX 4YYWA 2F1GA 2FYEA 4QH6A 5EF4A 2G8EA 4AXMA 2OULA 2IPPB 3P5VA 3V6CA 3V6EA 2ATOA 4Q8HA 2P0RA 3HWNA 1TU6A 1EWPA 2PBHA 3OVXA 1S4VA 2R9MA 4MZSA 5FPWA 3KX1A 4WA6A 1AU3A 4CDEB 1ICFA 1NB3A 1CVZA 1ME3A 3RVXA 5PADA 2DZZA 3P5XA 3BOWA 3BWKA 4Q8GA 4W5CA 4FJCA 4YYSA 2F7DA 3KWZA 4X6JA 4XR7A 4X6HA 1X9YA 2VHFA 1GECE 1PPOA 2XU5A 1KHPA 1K3BB 4PP2E 4BQVA 3C9EA 3WXFA 1CB5A 3O0UA 4KLBA 3ERVA 9PAPA 2DC6A 2NQGA 4RY2A 1AU2A 1AYVA 1YALA 3H8CA 1KFXL 1TLOA 1MHWA 1JQPA 4FK5A 2HD5A 1DEUA 4MZOA 4QRVA 1F2AA 4QBBA 3OF8A 4CZWA 1AYUA 2HXZA 1VJVA 1PPPA 3IHPA 3RVWA 2R9OA 2DCBA 3I3TA 3I06A 3QSDA 1XKGA 3P5WA 1YK8A
chains in the Genus database with same CATH superfamily
2DOSA 1BQIA 1AU4A 3PHXA 4W5BA 4YVAA 1CQDA 3PNRA 2DC9A 2FRAA 2R9CA 2AYNA 3MP2A 3MHHA 3P5UA 5J94A 2R9NA 1DKIA 2GHUA 3MORA 4OW0A 1ZIVA 3IEJA 2JRIA 5F02A 2FQ9A 2XU1A 3NHEA 3OF9A 2BDZA 4ZTBA 4RF1A 1BGOA 4OEMA 1PADA 1MDWA 4P6GA 4QRGA 3BCNA 4AXLA 1CV8A 2P7UA 4DMXA 2G8JA 3LFYA 1DF0A 1GMYA 2IBIA 3IV2A 1NQCA 1ITOA 5CVNB 2HWKA 3S3RA 4D8IA 1U9VA 3CH2X 3BPFA 4RKXA 3TNXA 1F2BA 2AUXA 3MHSA 2JQFR 3N3KA 5JH3A 2FUDA 1TL9A 4D8BA 2DC8A 4CDCB 1YK7A 2ARYA 1CJLA 3B79A 3B21A 3IUTA 4OELA 3QT4A 4PI3A 2DCDA 3H6SA 1YT7A 3PHWA 1BY8A 3GCBA 1EWLA 2Y5BA 3E9SA 2PNSA 5JZEA 3F5VA 2B1NA 1KXRA 3HD3A 4K7CA 1AU0A 4YV8A 1CS8A 4N4ZA 1MIRA 4OVZB 3M99A 4I05A 4CDDB 2AS8A 2YJCA 1PXVA 4YYQA 2FTDA 1HUCB 1PIPA 1SP4B 2AVWA 2G7YA 1GCBA 1THEA 3CBJA 1AYWA 1F2CA 4PP1A 3IMAA 4X6IA 3K24A 1UKFA 2O6XA 2B1MA 2YJ9A 1Q6KA 4QRXA 3OVZA 4RF0A 5A24A 2BTWA 4BOQA 2NQAA 4W4UA 2CIOA 3K8UA 4YYRA 1CTEA 3O1GA 8PCHA 3TMPA 1QDQA 2AIMA 2AGAA 2H7JA 3LXSA 4N79A 1QMYA 4BOPA 4G54A 1Y4HA 2DJGB 1QOLA 1GLOA 2Y6EA 7PCKA 3PDFA 1EF7A 2NQIA 4HWYA 2R6NA 3BC3A 1U9XA 2FO5A 1SNKA 4BSQA 3KWBX 2FRQA 4R3DA 3F75A 3KFQA 1CSBB 3CBKA 1AECA 4M0WA 3S3QA 2XU4A 3HHAA 4YYVA 3PBHA 2J7QA 1STFE 1ATKA 3IFUA 4MM3B 4CDFB 1NB5A 1MS6A 2DC7A 4BS5A 3RNVA 3OQCA 2YJ8A 1NLJA 2HH5A 4FIPA 2AU1A 1KFUL 3K9MA 3PHUA 2DZYA 2DCCA 3PT2A 3KKUA 3USVA 3QJ3A 2DJFB 4BPVA 1PPDA 3C0RA 1YVBA 2AYOA 2VHSA 3DF0A 3WXGA 2OP3A 2GFOA 3KSEA 4P16A 1QXPA 2R9FA 2YJBA 1A6RA 2PADA 3RVVA 5JA7A 4ZUXU 1EWOA 3IOQA 1M6DA 3MTVA 3ZUAA 1IWDA 4OVZA 1PCIA 2BU3A 2BDLA 1FH0A 4WURA 6PADA 4MSXA 4A5UA 1BP4A 1O0EA 1ZCMA 1KHQA 3OISA 2HHNA 3N4CA 1PE6A 1U9WA 2FT2A 2ACTA 2E03A 2Z84A 3H7DA 4BS6A 4RNAA 2J7QC 4PADA 5EGWA 2NQDB 4GUAA 2PREA 3HHIA 4I07A 2E00A 5CHVA 4IUMA 4HXDB 4YYUA 1ME4A 2JQGR 5K16A 2CB5A 1PVJA 2E02A 4DMYA 5CHTA 2AUZA 3CH3X 3MTNA 2G6DA 3N3GA 3AI8A 1PPNA 2YJ2A 1F29A 2P86A 1NL6A 3U8EA 3ZNHA 4XUIA 2WBFX 1NPZA 3BPMA 5CVOB 3W31A 3PW3A 1VSNA 1Y08A 2C0YA 2OZ2A 5EZSA 5CVMA 4PT5A 2DCAA 2UZJA 1EWMA 3H89A 3H8BA 3BY4A 2E01A 3MJ5A 1CPJA 1MEMA 3WXEA 1MEGA 4P6EA 3KW9A 1POPA 1AIMA 1PBHA 3E1ZB 1U5IA 4BOSA 4N8WA 2XU3A 3D6SA 4I04A 1U9QX 4BOZA 4YYWA 2F1GA 2FYEA 4QH6A 5EF4A 2G8EA 4AXMA 2OULA 2IPPB 4D8EA 3P5VA 3PRPA 3PSEA 3V6CA 3V6EA 2ATOA 4Q8HA 2P0RA 3HWNA 1TU6A 1EWPA 2PBHA 3BBAA 3OVXA 1S4VA 2R9MA 4MZSA 5FPWA 3O65A 3KX1A 4WA6A 1AU3A 4CDEB 1ICFA 1NB3A 1CVZA 1ME3A 5E6JA 3RVXA 5PADA 2DZZA 4BOUA 3P5XA 3BOWA 3BWKA 4Q8GA 4W5CA 4FJCA 2JTCA 4YYSA 2F7DA 3KWZA 4X6JA 4XR7A 4X6HA 1X9YA 2VHFA 4IP3A 4REZA 1YZBA 1GECE 1PPOA 2XU5A 1KHPA 1K3BB 4PP2E 4BQVA 3C9EA 3WXFA 1CB5A 3O0UA 4KLBA 4XZXA 3ERVA 9PAPA 2DC6A 2NQGA 4RY2A 1AU2A 1AYVA 1YALA 3H8CA 1KFXL 3W30A 1TLOA 1MHWA 1JQPA 4FK5A 2HD5A 5EZQA 1DEUA 4MZOA 5KO3A 4QRVA 1F2AA 4QBBA 3OF8A 4CZWA 1AYUA 2HXZA 1VJVA 2BTWB 1PPPA 3IHPA 3RVWA 2R9OA 2DCBA 3I3TA 3TRKA 3PRMA 3I06A 3QSDA 3BB7A 1XKGA 2FE8A 3P5WA 4MI7A 1YK8A
chains in the Genus database with same CATH topology
1BQIA 1AU4A 4W5BA 4YVAA 1CQDA 3PNRA 2DC9A 2FRAA 2R9CA 2AYNA 3MHHA 3P5UA 5J94A 2R9NA 2GHUA 3MORA 1GX3A 1ZIVA 3IEJA 5F02A 2FQ9A 2XU1A 3NHEA 3OF9A 2BDZA 1BGOA 4OEMA 1PADA 1MDWA 4P6GA 4QRGA 3BCNA 4AXLA 1CV8A 2P7UA 4DMXA 2G8JA 3LFYA 1DF0A 1GMYA 2IBIA 3IV2A 1NQCA 1ITOA 5CVNB 3S3RA 1U9VA 3CH2X 3BPFA 3TNXA 1F2BA 2AUXA 2JQFR 3MHSA 3N3KA 5JH3A 2FUDA 1TL9A 2DC8A 4CDCB 1YK7A 2ARYA 1CJLA 3B79A 3IUTA 4OELA 3QT4A 2BSZA 4PI3A 2DCDA 3H6SA 1YT7A 1BY8A 3GCBA 1EWLA 2Y5BA 2PNSA 3F5VA 2B1NA 1KXRA 4NV7A 3HD3A 4K7CA 1AU0A 4YV8A 1CS8A 4N4ZA 1MIRA 4B55A 3M99A 4I05A 4CDDB 2AS8A 2YJCA 1PXVA 4YYQA 2FTDA 1HUCB 1PIPA 1SP4B 2AVWA 2G7YA 1GCBA 1THEA 3CBJA 1AYWA 1F2CA 4PP1A 3IMAA 1W6FA 4X6IA 1W4TA 3K24A 2O6XA 2B1MA 2YJ9A 1Q6KA 4QRXA 3OVZA 5A24A 2NQAA 4W4UA 2CIOA 3K8UA 4YYRA 1CTEA 3O1GA 8PCHA 1QDQA 2AIMA 2H7JA 3LXSA 1W5RA 4N79A 1QMYA 4G54A 1Y4HA 2DJGB 1QOLA 1GLOA 2Y6EA 7PCKA 3PDFA 1EF7A 2NQIA 4HWYA 2R6NA 3BC3A 1U9XA 2FO5A 1SNKA 4BSQA 3KWBX 2FRQA 3F75A 3KFQA 1CSBB 3CBKA 1AECA 3S3QA 2XU4A 3HHAA 4YYVA 3PBHA 1STFE 1ATKA 4CDFB 1NB5A 1MS6A 2DC7A 4BS5A 2YJ8A 1NLJA 2HH5A 4FIPA 2AU1A 1KFUL 3K9MA 2DZYA 2DCCA 3KKUA 3USVA 3QJ3A 2DJFB 4BPVA 1PPDA 1YVBA 2AYOA 2VHSA 3DF0A 3WXGA 2OP3A 2GFOA 3KSEA 1QXPA 2R9FA 2YJBA 1A6RA 2PADA 3RVVA 5JA7A 4ZUXU 1EWOA 3IOQA 1M6DA 3ZUAA 1IWDA 1PCIA 2BDLA 1FH0A 6PADA 4MSXA 1BP4A 1O0EA 1ZCMA 1KHQA 3OISA 2HHNA 3N4CA 1PE6A 1U9WA 2FT2A 2ACTA 2E03A 3H7DA 4BS6A 3LTWA 4PADA 5EGWA 2NQDB 2PREA 3HHIA 4I07A 2E00A 5CHVA 4C5PA 4YYUA 1ME4A 2JQGR 5K16A 2CB5A 2E02A 4DMYA 5CHTA 2AUZA 3CH3X 3MTNA 2G6DA 3N3GA 3AI8A 1PPNA 2YJ2A 1F29A 2P86A 1E2TA 1NL6A 3U8EA 4XUIA 2WBFX 1NPZA 3BPMA 5CVOB 3PW3A 1VSNA 1Y08A 2C0YA 2OZ2A 5CVMA 2DCAA 3H89A 1EWMA 3H8BA 2E01A 1CPJA 1MEMA 3WXEA 1MEGA 4P6EA 3KW9A 1POPA 1AIMA 1PBHA 3E1ZB 1U5IA 4N8WA 2XU3A 3D6SA 4I04A 1U9QX 4YYWA 2F1GA 2FYEA 4GUZA 4QH6A 5EF4A 2G8EA 4AXMA 2OULA 2IPPB 3P5VA 3V6CA 3V6EA 2ATOA 4Q8HA 2P0RA 3HWNA 1TU6A 1EWPA 2PBHA 3OVXA 1S4VA 2R9MA 4MZSA 5FPWA 3KX1A 4WA6A 1AU3A 4CDEB 1ICFA 1NB3A 1CVZA 1ME3A 3RVXA 5PADA 2DZZA 3D9WA 3P5XA 3BOWA 3BWKA 4BGFA 4Q8GA 4W5CA 4FJCA 4YYSA 2F7DA 4NV8A 3KWZA 4X6JA 4XR7A 4X6HA 1X9YA 2VHFA 1GECE 1PPOA 2XU5A 1KHPA 1K3BB 4PP2E 4BQVA 3C9EA 3WXFA 1CB5A 3O0UA 4KLBA 3ERVA 9PAPA 2DC6A 2NQGA 4RY2A 1AU2A 1AYVA 2VFBA 1YALA 3H8CA 1KFXL 1TLOA 1MHWA 1JQPA 4FK5A 2HD5A 1DEUA 4MZOA 4QRVA 1F2AA 4QBBA 3OF8A 4CZWA 1AYUA 2HXZA 1VJVA 1PPPA 3IHPA 3RVWA 2R9OA 2DCBA 3I3TA 3I06A 3QSDA 1XKGA 3P5WA 2VFCA 1YK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BQI A;  1AU4 A;  4W5B A;  4YVA A;  1CQD A;  3PNR A;  2DC9 A;  2FRA A;  2R9C A;  2AYN A;  3MHH A;  3P5U A;  5J94 A;  2R9N A;  2GHU A;  3MOR A;  1ZIV A;  3IEJ A;  5F02 A;  2FQ9 A;  2XU1 A;  3NHE A;  3OF9 A;  2BDZ A;  1BGO A;  4OEM A;  1PAD A;  1MDW A;  4P6G A;  4QRG A;  3BCN A;  4AXL A;  1CV8 A;  2P7U A;  4DMX A;  2G8J A;  3LFY A;  1DF0 A;  1GMY A;  2IBI A;  3IV2 A;  1NQC A;  1ITO A;  5CVN B;  3S3R A;  1U9V A;  3CH2 X;  3BPF A;  3TNX A;  1F2B A;  2AUX A;  2JQF R;  3MHS A;  3N3K A;  5JH3 A;  2FUD A;  1TL9 A;  2DC8 A;  4CDC B;  1YK7 A;  2ARY A;  1CJL A;  3B79 A;  3IUT A;  4OEL A;  3QT4 A;  4PI3 A;  2DCD A;  3H6S A;  1YT7 A;  1BY8 A;  3GCB A;  1EWL A;  2Y5B A;  2PNS A;  3F5V A;  2B1N A;  1KXR A;  3HD3 A;  4K7C A;  1AU0 A;  4YV8 A;  1CS8 A;  4N4Z A;  1MIR A;  3M99 A;  4I05 A;  4CDD B;  2AS8 A;  2YJC A;  1PXV A;  4YYQ A;  2FTD A;  1HUC B;  1PIP A;  1SP4 B;  2AVW A;  2G7Y A;  1GCB A;  1THE A;  3CBJ A;  1AYW A;  1F2C A;  4PP1 A;  3IMA A;  4X6I A;  3K24 A;  2O6X A;  2B1M A;  2YJ9 A;  1Q6K A;  4QRX A;  3OVZ A;  5A24 A;  2NQA A;  4W4U A;  2CIO A;  3K8U A;  4YYR A;  1CTE A;  3O1G A;  8PCH A;  1QDQ A;  2AIM A;  2H7J A;  3LXS A;  4N79 A;  1QMY A;  4G54 A;  1Y4H A;  2DJG B;  1QOL A;  1GLO A;  2Y6E A;  7PCK A;  3PDF A;  1EF7 A;  2NQI A;  4HWY A;  2R6N A;  3BC3 A;  1U9X A;  2FO5 A;  1SNK A;  4BSQ A;  3KWB X;  2FRQ A;  3F75 A;  3KFQ A;  1CSB B;  3CBK A;  1AEC A;  3S3Q A;  2XU4 A;  3HHA A;  4YYV A;  3PBH A;  1STF E;  1ATK A;  4CDF B;  1NB5 A;  1MS6 A;  2DC7 A;  4BS5 A;  2YJ8 A;  1NLJ A;  2HH5 A;  4FIP A;  2AU1 A;  1KFU L;  3K9M A;  2DZY A;  2DCC A;  3KKU A;  3USV A;  3QJ3 A;  2DJF B;  4BPV A;  1PPD A;  1YVB A;  2AYO A;  2VHS A;  3DF0 A;  3WXG A;  2OP3 A;  2GFO A;  3KSE A;  1QXP A;  2R9F A;  2YJB A;  1A6R A;  2PAD A;  3RVV A;  5JA7 A;  4ZUX U;  1EWO A;  3IOQ A;  1M6D A;  3ZUA A;  1IWD A;  1PCI A;  2BDL A;  1FH0 A;  6PAD A;  4MSX A;  1BP4 A;  1O0E A;  1ZCM A;  1KHQ A;  3OIS A;  2HHN A;  3N4C A;  1PE6 A;  1U9W A;  2FT2 A;  2ACT A;  2E03 A;  3H7D A;  4BS6 A;  4PAD A;  5EGW A;  2NQD B;  2PRE A;  3HHI A;  4I07 A;  2E00 A;  5CHV A;  4YYU A;  1ME4 A;  2JQG R;  5K16 A;  2CB5 A;  2E02 A;  4DMY A;  5CHT A;  2AUZ A;  3CH3 X;  3MTN A;  2G6D A;  3N3G A;  3AI8 A;  1PPN A;  2YJ2 A;  1F29 A;  2P86 A;  1NL6 A;  3U8E A;  4XUI A;  2WBF X;  1NPZ A;  3BPM A;  5CVO B;  3PW3 A;  1VSN A;  1Y08 A;  2C0Y A;  2OZ2 A;  5CVM A;  2DCA A;  3H89 A;  1EWM A;  3H8B A;  2E01 A;  1CPJ A;  1MEM A;  3WXE A;  1MEG A;  4P6E A;  3KW9 A;  1POP A;  1AIM A;  1PBH A;  3E1Z B;  1U5I A;  4N8W A;  2XU3 A;  3D6S A;  4I04 A;  1U9Q X;  4YYW A;  2F1G A;  2FYE A;  4QH6 A;  5EF4 A;  2G8E A;  4AXM A;  2OUL A;  2IPP B;  3P5V A;  3V6C A;  3V6E A;  2ATO A;  4Q8H A;  2P0R A;  3HWN A;  1TU6 A;  1EWP A;  2PBH A;  3OVX A;  1S4V A;  2R9M A;  4MZS A;  5FPW A;  3KX1 A;  4WA6 A;  1AU3 A;  4CDE B;  1ICF A;  1NB3 A;  1CVZ A;  1ME3 A;  3RVX A;  5PAD A;  2DZZ A;  3P5X A;  3BOW A;  3BWK A;  4Q8G A;  4W5C A;  4FJC A;  4YYS A;  2F7D A;  3KWZ A;  4X6J A;  4XR7 A;  4X6H A;  1X9Y A;  2VHF A;  1GEC E;  1PPO A;  2XU5 A;  1KHP A;  1K3B B;  4PP2 E;  4BQV A;  3C9E A;  3WXF A;  1CB5 A;  3O0U A;  4KLB A;  3ERV A;  9PAP A;  2DC6 A;  2NQG A;  4RY2 A;  1AU2 A;  1AYV A;  1YAL A;  3H8C A;  1KFX L;  1TLO A;  1MHW A;  1JQP A;  4FK5 A;  2HD5 A;  1DEU A;  4MZO A;  4QRV A;  1F2A A;  4QBB A;  3OF8 A;  4CZW A;  1AYU A;  2HXZ A;  1VJV A;  1PPP A;  3IHP A;  3RVW A;  2R9O A;  2DCB A;  3I3T A;  3I06 A;  3QSD A;  1XKG A;  3P5W A;  1YK8 A; 
#chains in the Genus database with same CATH topology
 2DOS A;  1BQI A;  1AU4 A;  3PHX A;  4W5B A;  4YVA A;  1CQD A;  3PNR A;  2DC9 A;  2FRA A;  2R9C A;  2AYN A;  3MP2 A;  3MHH A;  3P5U A;  5J94 A;  2R9N A;  1DKI A;  2GHU A;  3MOR A;  4OW0 A;  1ZIV A;  3IEJ A;  2JRI A;  5F02 A;  2FQ9 A;  2XU1 A;  3NHE A;  3OF9 A;  2BDZ A;  4ZTB A;  4RF1 A;  1BGO A;  4OEM A;  1PAD A;  1MDW A;  4P6G A;  4QRG A;  3BCN A;  4AXL A;  1CV8 A;  2P7U A;  4DMX A;  2G8J A;  3LFY A;  1DF0 A;  1GMY A;  2IBI A;  3IV2 A;  1NQC A;  1ITO A;  5CVN B;  2HWK A;  3S3R A;  4D8I A;  1U9V A;  3CH2 X;  3BPF A;  4RKX A;  3TNX A;  1F2B A;  2AUX A;  3MHS A;  2JQF R;  3N3K A;  5JH3 A;  2FUD A;  1TL9 A;  4D8B A;  2DC8 A;  4CDC B;  1YK7 A;  2ARY A;  1CJL A;  3B79 A;  3B21 A;  3IUT A;  4OEL A;  3QT4 A;  4PI3 A;  2DCD A;  3H6S A;  1YT7 A;  3PHW A;  1BY8 A;  3GCB A;  1EWL A;  2Y5B A;  3E9S A;  2PNS A;  5JZE A;  3F5V A;  2B1N A;  1KXR A;  3HD3 A;  4K7C A;  1AU0 A;  4YV8 A;  1CS8 A;  4N4Z A;  1MIR A;  4OVZ B;  3M99 A;  4I05 A;  4CDD B;  2AS8 A;  2YJC A;  1PXV A;  4YYQ A;  2FTD A;  1HUC B;  1PIP A;  1SP4 B;  2AVW A;  2G7Y A;  1GCB A;  1THE A;  3CBJ A;  1AYW A;  1F2C A;  4PP1 A;  3IMA A;  4X6I A;  3K24 A;  1UKF A;  2O6X A;  2B1M A;  2YJ9 A;  1Q6K A;  4QRX A;  3OVZ A;  4RF0 A;  5A24 A;  2BTW A;  4BOQ A;  2NQA A;  4W4U A;  2CIO A;  3K8U A;  4YYR A;  1CTE A;  3O1G A;  8PCH A;  3TMP A;  1QDQ A;  2AIM A;  2AGA A;  2H7J A;  3LXS A;  4N79 A;  1QMY A;  4BOP A;  4G54 A;  1Y4H A;  2DJG B;  1QOL A;  1GLO A;  2Y6E A;  7PCK A;  3PDF A;  1EF7 A;  2NQI A;  4HWY A;  2R6N A;  3BC3 A;  1U9X A;  2FO5 A;  1SNK A;  4BSQ A;  3KWB X;  2FRQ A;  4R3D A;  3F75 A;  3KFQ A;  1CSB B;  3CBK A;  1AEC A;  4M0W A;  3S3Q A;  2XU4 A;  3HHA A;  4YYV A;  3PBH A;  2J7Q A;  1STF E;  1ATK A;  3IFU A;  4MM3 B;  4CDF B;  1NB5 A;  1MS6 A;  2DC7 A;  4BS5 A;  3RNV A;  3OQC A;  2YJ8 A;  1NLJ A;  2HH5 A;  4FIP A;  2AU1 A;  1KFU L;  3K9M A;  3PHU A;  2DZY A;  2DCC A;  3PT2 A;  3KKU A;  3USV A;  3QJ3 A;  2DJF B;  4BPV A;  1PPD A;  3C0R A;  1YVB A;  2AYO A;  2VHS A;  3DF0 A;  3WXG A;  2OP3 A;  2GFO A;  3KSE A;  4P16 A;  1QXP A;  2R9F A;  2YJB A;  1A6R A;  2PAD A;  3RVV A;  5JA7 A;  4ZUX U;  1EWO A;  3IOQ A;  1M6D A;  3MTV A;  3ZUA A;  1IWD A;  4OVZ A;  1PCI A;  2BU3 A;  2BDL A;  1FH0 A;  4WUR A;  6PAD A;  4MSX A;  4A5U A;  1BP4 A;  1O0E A;  1ZCM A;  1KHQ A;  3OIS A;  2HHN A;  3N4C A;  1PE6 A;  1U9W A;  2FT2 A;  2ACT A;  2E03 A;  2Z84 A;  3H7D A;  4BS6 A;  4RNA A;  2J7Q C;  4PAD A;  5EGW A;  2NQD B;  4GUA A;  2PRE A;  3HHI A;  4I07 A;  2E00 A;  5CHV A;  4IUM A;  4HXD B;  4YYU A;  1ME4 A;  2JQG R;  5K16 A;  2CB5 A;  1PVJ A;  2E02 A;  4DMY A;  5CHT A;  2AUZ A;  3CH3 X;  3MTN A;  2G6D A;  3N3G A;  3AI8 A;  1PPN A;  2YJ2 A;  1F29 A;  2P86 A;  1NL6 A;  3U8E A;  3ZNH A;  4XUI A;  2WBF X;  1NPZ A;  3BPM A;  5CVO B;  3W31 A;  3PW3 A;  1VSN A;  1Y08 A;  2C0Y A;  2OZ2 A;  5EZS A;  5CVM A;  4PT5 A;  2DCA A;  2UZJ A;  1EWM A;  3H89 A;  3H8B A;  3BY4 A;  2E01 A;  3MJ5 A;  1CPJ A;  1MEM A;  3WXE A;  1MEG A;  4P6E A;  3KW9 A;  1POP A;  1AIM A;  1PBH A;  3E1Z B;  1U5I A;  4BOS A;  4N8W A;  2XU3 A;  3D6S A;  4I04 A;  1U9Q X;  4BOZ A;  4YYW A;  2F1G A;  2FYE A;  4QH6 A;  5EF4 A;  2G8E A;  4AXM A;  2OUL A;  2IPP B;  4D8E A;  3P5V A;  3PRP A;  3PSE A;  3V6C A;  3V6E A;  2ATO A;  4Q8H A;  2P0R A;  3HWN A;  1TU6 A;  1EWP A;  2PBH A;  3BBA A;  3OVX A;  1S4V A;  2R9M A;  4MZS A;  5FPW A;  3O65 A;  3KX1 A;  4WA6 A;  1AU3 A;  4CDE B;  1ICF A;  1NB3 A;  1CVZ A;  1ME3 A;  5E6J A;  3RVX A;  5PAD A;  2DZZ A;  4BOU A;  3P5X A;  3BOW A;  3BWK A;  4Q8G A;  4W5C A;  4FJC A;  2JTC A;  4YYS A;  2F7D A;  3KWZ A;  4X6J A;  4XR7 A;  4X6H A;  1X9Y A;  2VHF A;  4IP3 A;  4REZ A;  1YZB A;  1GEC E;  1PPO A;  2XU5 A;  1KHP A;  1K3B B;  4PP2 E;  4BQV A;  3C9E A;  3WXF A;  1CB5 A;  3O0U A;  4KLB A;  4XZX A;  3ERV A;  9PAP A;  2DC6 A;  2NQG A;  4RY2 A;  1AU2 A;  1AYV A;  1YAL A;  3H8C A;  1KFX L;  3W30 A;  1TLO A;  1MHW A;  1JQP A;  4FK5 A;  2HD5 A;  5EZQ A;  1DEU A;  4MZO A;  5KO3 A;  4QRV A;  1F2A A;  4QBB A;  3OF8 A;  4CZW A;  1AYU A;  2HXZ A;  1VJV A;  2BTW B;  1PPP A;  3IHP A;  3RVW A;  2R9O A;  2DCB A;  3I3T A;  3TRK A;  3PRM A;  3I06 A;  3QSD A;  3BB7 A;  1XKG A;  2FE8 A;  3P5W A;  4MI7 A;  1YK8 A; 
#chains in the Genus database with same CATH homology
 1BQI A;  1AU4 A;  4W5B A;  4YVA A;  1CQD A;  3PNR A;  2DC9 A;  2FRA A;  2R9C A;  2AYN A;  3MHH A;  3P5U A;  5J94 A;  2R9N A;  2GHU A;  3MOR A;  1GX3 A;  1ZIV A;  3IEJ A;  5F02 A;  2FQ9 A;  2XU1 A;  3NHE A;  3OF9 A;  2BDZ A;  1BGO A;  4OEM A;  1PAD A;  1MDW A;  4P6G A;  4QRG A;  3BCN A;  4AXL A;  1CV8 A;  2P7U A;  4DMX A;  2G8J A;  3LFY A;  1DF0 A;  1GMY A;  2IBI A;  3IV2 A;  1NQC A;  1ITO A;  5CVN B;  3S3R A;  1U9V A;  3CH2 X;  3BPF A;  3TNX A;  1F2B A;  2AUX A;  2JQF R;  3MHS A;  3N3K A;  5JH3 A;  2FUD A;  1TL9 A;  2DC8 A;  4CDC B;  1YK7 A;  2ARY A;  1CJL A;  3B79 A;  3IUT A;  4OEL A;  3QT4 A;  2BSZ A;  4PI3 A;  2DCD A;  3H6S A;  1YT7 A;  1BY8 A;  3GCB A;  1EWL A;  2Y5B A;  2PNS A;  3F5V A;  2B1N A;  1KXR A;  4NV7 A;  3HD3 A;  4K7C A;  1AU0 A;  4YV8 A;  1CS8 A;  4N4Z A;  1MIR A;  4B55 A;  3M99 A;  4I05 A;  4CDD B;  2AS8 A;  2YJC A;  1PXV A;  4YYQ A;  2FTD A;  1HUC B;  1PIP A;  1SP4 B;  2AVW A;  2G7Y A;  1GCB A;  1THE A;  3CBJ A;  1AYW A;  1F2C A;  4PP1 A;  3IMA A;  1W6F A;  4X6I A;  1W4T A;  3K24 A;  2O6X A;  2B1M A;  2YJ9 A;  1Q6K A;  4QRX A;  3OVZ A;  5A24 A;  2NQA A;  4W4U A;  2CIO A;  3K8U A;  4YYR A;  1CTE A;  3O1G A;  8PCH A;  1QDQ A;  2AIM A;  2H7J A;  3LXS A;  1W5R A;  4N79 A;  1QMY A;  4G54 A;  1Y4H A;  2DJG B;  1QOL A;  1GLO A;  2Y6E A;  7PCK A;  3PDF A;  1EF7 A;  2NQI A;  4HWY A;  2R6N A;  3BC3 A;  1U9X A;  2FO5 A;  1SNK A;  4BSQ A;  3KWB X;  2FRQ A;  3F75 A;  3KFQ A;  1CSB B;  3CBK A;  1AEC A;  3S3Q A;  2XU4 A;  3HHA A;  4YYV A;  3PBH A;  1STF E;  1ATK A;  4CDF B;  1NB5 A;  1MS6 A;  2DC7 A;  4BS5 A;  2YJ8 A;  1NLJ A;  2HH5 A;  4FIP A;  2AU1 A;  1KFU L;  3K9M A;  2DZY A;  2DCC A;  3KKU A;  3USV A;  3QJ3 A;  2DJF B;  4BPV A;  1PPD A;  1YVB A;  2AYO A;  2VHS A;  3DF0 A;  3WXG A;  2OP3 A;  2GFO A;  3KSE A;  1QXP A;  2R9F A;  2YJB A;  1A6R A;  2PAD A;  3RVV A;  5JA7 A;  4ZUX U;  1EWO A;  3IOQ A;  1M6D A;  3ZUA A;  1IWD A;  1PCI A;  2BDL A;  1FH0 A;  6PAD A;  4MSX A;  1BP4 A;  1O0E A;  1ZCM A;  1KHQ A;  3OIS A;  2HHN A;  3N4C A;  1PE6 A;  1U9W A;  2FT2 A;  2ACT A;  2E03 A;  3H7D A;  4BS6 A;  3LTW A;  4PAD A;  5EGW A;  2NQD B;  2PRE A;  3HHI A;  4I07 A;  2E00 A;  5CHV A;  4C5P A;  4YYU A;  1ME4 A;  2JQG R;  5K16 A;  2CB5 A;  2E02 A;  4DMY A;  5CHT A;  2AUZ A;  3CH3 X;  3MTN A;  2G6D A;  3N3G A;  3AI8 A;  1PPN A;  2YJ2 A;  1F29 A;  2P86 A;  1E2T A;  1NL6 A;  3U8E A;  4XUI A;  2WBF X;  1NPZ A;  3BPM A;  5CVO B;  3PW3 A;  1VSN A;  1Y08 A;  2C0Y A;  2OZ2 A;  5CVM A;  2DCA A;  3H89 A;  1EWM A;  3H8B A;  2E01 A;  1CPJ A;  1MEM A;  3WXE A;  1MEG A;  4P6E A;  3KW9 A;  1POP A;  1AIM A;  1PBH A;  3E1Z B;  1U5I A;  4N8W A;  2XU3 A;  3D6S A;  4I04 A;  1U9Q X;  4YYW A;  2F1G A;  2FYE A;  4GUZ A;  4QH6 A;  5EF4 A;  2G8E A;  4AXM A;  2OUL A;  2IPP B;  3P5V A;  3V6C A;  3V6E A;  2ATO A;  4Q8H A;  2P0R A;  3HWN A;  1TU6 A;  1EWP A;  2PBH A;  3OVX A;  1S4V A;  2R9M A;  4MZS A;  5FPW A;  3KX1 A;  4WA6 A;  1AU3 A;  4CDE B;  1ICF A;  1NB3 A;  1CVZ A;  1ME3 A;  3RVX A;  5PAD A;  2DZZ A;  3D9W A;  3P5X A;  3BOW A;  3BWK A;  4BGF A;  4Q8G A;  4W5C A;  4FJC A;  4YYS A;  2F7D A;  4NV8 A;  3KWZ A;  4X6J A;  4XR7 A;  4X6H A;  1X9Y A;  2VHF A;  1GEC E;  1PPO A;  2XU5 A;  1KHP A;  1K3B B;  4PP2 E;  4BQV A;  3C9E A;  3WXF A;  1CB5 A;  3O0U A;  4KLB A;  3ERV A;  9PAP A;  2DC6 A;  2NQG A;  4RY2 A;  1AU2 A;  1AYV A;  2VFB A;  1YAL A;  3H8C A;  1KFX L;  1TLO A;  1MHW A;  1JQP A;  4FK5 A;  2HD5 A;  1DEU A;  4MZO A;  4QRV A;  1F2A A;  4QBB A;  3OF8 A;  4CZW A;  1AYU A;  2HXZ A;  1VJV A;  1PPP A;  3IHP A;  3RVW A;  2R9O A;  2DCB A;  3I3T A;  3I06 A;  3QSD A;  1XKG A;  3P5W A;  2VFC A;  1YK8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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