2DC6A

X-ray crystal structure analysis of bovine spleen cathepsin b-ca073 complex
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
253
structure length
251
Chain Sequence
LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMPCT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
rcsb
molecule tags Hydrolase
molecule keywords cathepsin B
total genus 74
structure length 251
sequence length 253
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2005-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2dc6A00
4P6EA 4QBBA 2B1NA 3ERVA 5F02A 2YJBA 1HUCB 3RVVA 2AS8A 2DC9A 1AU4A 4RY2A 1QXPA 1MHWA 3S3RA 4Q8HA 3P5WA 5CVOB 1CV8A 2AIMA 1ZCMA 4PP2E 2C0YA 3ZUAA 1KXRA 2YJ8A 2XU3A 4I04A 1BGOA 1Q6KA 1PBHA 4DMXA 1SP4B 2OZ2A 3QT4A 4CDDB 2YJ2A 1CS8A 2R9OA 3USVA 4DMYA 2GHUA 2ATOA 3OF8A 2YJ9A 3MORA 2AYOA 3I06A 3KKUA 2R6NA 1F29A 1STFE 2FTDA 1CSBB 2IBIA 3C9EA 1AIMA 3K9MA 2R9NA 2FRAA 1PPNA 1GCBA 4ZUXU 2R9CA 4YYVA 2P86A 4HWYA 1MEGA 1AU2A 2AYNA 1TL9A 3CBKA 1A6RA 1DF0A 4MZSA 1NQCA 2DCAA 5EGWA 1NPZA 1EWLA 3D6SA 1AYVA 5EF4A 2FO5A 2NQDB 1CPJA 1U9VA 5CHTA 1K3BB 1QMYA 4MZOA 2H7JA 3B79A 3IHPA 1AU0A 2G8EA 3IV2A 3RVWA 3QJ3A 4YYSA 4YYWA 2ACTA 1MIRA 4BPVA 2DZZA 3BWKA 4W5CA 3KW9A 1VSNA 2E03A 1EWPA 3OF9A 3P5VA 2DCDA 2ARYA 1F2CA 3H7DA 4CDEB 2DZYA 3PW3A 3E1ZB 4QRXA 1CVZA 4K7CA 4XR7A 2R9MA 3N3GA 1TLOA 4QH6A 2G7YA 2BDLA 3PBHA 1O0EA 4YVAA 1YK8A 2PADA 1NB5A 2HH5A 2DCCA 2R9FA 3WXEA 2NQIA 4XUIA 4YV8A 3KFQA 3N4CA 3IEJA 3BPFA 5PADA 5K16A 3TNXA 4BQVA 3I3TA 3NHEA 1ICFA 2AVWA 4CDFB 5FPWA 2DC6A 3M99A 2YJCA 3MHSA 3KSEA 3O0UA 1FH0A 3P5UA 1YK7A 3H6SA 1KFXL 1F2AA 2E00A 1U9XA 1BY8A 4X6JA 1NL6A 2PNSA 3QSDA 2NQGA 3DF0A 1PXVA 4AXLA 1NLJA 2DJGB 2F7DA 1VJVA 2GFOA 1BP4A 6PADA 2P7UA 3LFYA 1AECA 1XKGA 5CVNB 1MDWA 3OISA 4PP1A 1PPPA 1EWMA 4W4UA 4G54A 3H8CA 1PCIA 2IPPB 1POPA 2FUDA 4N79A 1CJLA 1U9QX 1AYUA 1KHPA 4Q8GA 1KFUL 4PI3A 4WA6A 4QRVA 1TU6A 1Y08A 3GCBA 1ZIVA 2XU5A 3IOQA 3K24A 4X6HA 8PCHA 1BQIA 3OVZA 3AI8A 3WXFA 1PPOA 2HD5A 3BPMA 2BDZA 2FRQA 2Y6EA 1SNKA 1M6DA 2CIOA 5JH3A 4OELA 2WBFX 1THEA 3PDFA 1JQPA 2OULA 2DC7A 3OVXA 2P0RA 1Y4HA 4BS5A 1PADA 1QOLA 4FJCA 1QDQA 3O1GA 1CQDA 3HHAA 2Y5BA 3CBJA 4YYUA 2AUXA 4I07A 2PREA 5JA7A 3PNRA 3S3QA 1MEMA 1YALA 3LXSA 3KWBX 3U8EA 4YYQA 3V6EA 9PAPA 4PADA 3MTNA 3K8UA 2G6DA 1ME3A 3N3KA 1MS6A 1X9YA 4W5BA 1PIPA 1EWOA 2E01A 4P6GA 2XU1A 4AXMA 1S4VA 4FIPA 2OP3A 2B1MA 5J94A 4N4ZA 3KX1A 5CHVA 2VHFA 2O6XA 3IMAA 2PBHA 4QRGA 1NB3A 4BS6A 3BOWA 1PE6A 2AU1A 1YT7A 1CB5A 3CH2X 1YVBA 2G8JA 5CVMA 4YYRA 4KLBA 3RVXA 1U5IA 4N8WA 1F2BA 2E02A 2AUZA 2HXZA 2F1GA 1ATKA 1ME4A 2DCBA 1KHQA 3H8BA 3V6CA 1CTEA 1ITOA 1GECE 2CB5A 4CZWA 2JQGR 2XU4A 4BSQA 4FK5A 4I05A 3F5VA 2FQ9A 3BCNA 3MHHA 3BC3A 3HWNA 1U9WA 4X6IA 1GMYA 2VHSA 3F75A 2DC8A 3IUTA 4MSXA 4OEMA 7PCKA 3KWZA 2NQAA 3WXGA 5A24A 1GLOA 3CH3X 1AYWA 1AU3A 4CDCB 1DEUA 3H89A 1PPDA 1IWDA 3P5XA 2FT2A 3HD3A 2JQFR 1EF7A 2DJFB 2HHNA 2FYEA 3HHIA
chains in the Genus database with same CATH superfamily
4P6EA 4QBBA 2B1NA 3ERVA 5F02A 3C0RA 2YJBA 3PRPA 1HUCB 3RVVA 2AS8A 2DC9A 1AU4A 4RY2A 3IFUA 1QXPA 1MHWA 3S3RA 4Q8HA 3P5WA 5CVOB 1CV8A 2AIMA 5KO3A 1ZCMA 4PP2E 3E9SA 1DKIA 2C0YA 3ZUAA 1KXRA 2YJ8A 2XU3A 4I04A 1BGOA 2J7QA 1Q6KA 1PBHA 4DMXA 1SP4B 2OZ2A 3QT4A 2J7QC 4CDDB 2YJ2A 4BOPA 1CS8A 2R9OA 3USVA 4DMYA 2GHUA 2ATOA 3OF8A 2YJ9A 3MORA 2AYOA 3I06A 3KKUA 2R6NA 1F29A 1STFE 3PHXA 2FTDA 1CSBB 2IBIA 3C9EA 1AIMA 3K9MA 2R9NA 2FRAA 1PPNA 1GCBA 4ZUXU 4A5UA 2R9CA 2DOSA 4YYVA 2P86A 4HWYA 4D8IA 1MEGA 1AU2A 2AYNA 4M0WA 1TL9A 3CBKA 3ZNHA 5EZQA 1A6RA 1DF0A 4MZSA 1NQCA 2DCAA 5EGWA 1NPZA 1EWLA 3D6SA 1AYVA 5EF4A 2FO5A 3PSEA 2NQDB 1CPJA 1U9VA 5CHTA 1K3BB 1QMYA 4MZOA 4R3DA 2H7JA 3B79A 3IHPA 1AU0A 2G8EA 2BTWA 3IV2A 3RVWA 3QJ3A 4YYSA 4YYWA 3BB7A 2ACTA 1MIRA 4BPVA 2DZZA 3BWKA 4W5CA 3KW9A 1VSNA 2E03A 1EWPA 3OF9A 3P5VA 4BOSA 4WURA 2DCDA 2ARYA 1F2CA 3H7DA 4BOQA 4CDEB 2DZYA 3PW3A 4D8BA 3E1ZB 1PVJA 4QRXA 3PHUA 1CVZA 3MP2A 4K7CA 4XR7A 2R9MA 3N3GA 1TLOA 4QH6A 5E6JA 2G7YA 2BDLA 3PBHA 1O0EA 4YVAA 1YK8A 1UKFA 2PADA 1NB5A 2HH5A 2JTCA 3BBAA 2DCCA 2R9FA 3WXEA 2NQIA 4XUIA 4YV8A 3PHWA 3KFQA 3N4CA 3IEJA 3BPFA 5PADA 5K16A 3TNXA 4BQVA 3I3TA 3NHEA 1ICFA 2AVWA 4CDFB 4RNAA 5FPWA 2DC6A 3M99A 2YJCA 3MHSA 3KSEA 3O0UA 1FH0A 4RF0A 3P5UA 1YK7A 3H6SA 1KFXL 3B21A 1F2AA 2E00A 1U9XA 1BY8A 4X6JA 1NL6A 2PNSA 3QSDA 2NQGA 4MM3B 3DF0A 1PXVA 2FE8A 4AXLA 1NLJA 2DJGB 2F7DA 1VJVA 2GFOA 1BP4A 6PADA 2P7UA 3LFYA 1AECA 1XKGA 5CVNB 3PRMA 1MDWA 3OISA 4PP1A 1PPPA 1EWMA 4W4UA 4G54A 5EZSA 3H8CA 2HWKA 3MJ5A 1PCIA 2IPPB 1POPA 4PT5A 2FUDA 3BY4A 4N79A 1CJLA 1U9QX 1AYUA 1KHPA 4Q8GA 1KFUL 4BOUA 4PI3A 4WA6A 4QRVA 1TU6A 1Y08A 5JZEA 3MTVA 3GCBA 1ZIVA 2XU5A 3IOQA 3K24A 3RNVA 4X6HA 8PCHA 1BQIA 3OVZA 3AI8A 3WXFA 4D8EA 1PPOA 3W30A 2HD5A 3BPMA 2BDZA 3PT2A 2FRQA 4OVZB 2UZJA 2Y6EA 1SNKA 1M6DA 2CIOA 5JH3A 4OELA 2WBFX 1THEA 3PDFA 1JQPA 2JRIA 2OULA 2DC7A 3OVXA 2P0RA 1Y4HA 4BS5A 1PADA 1QOLA 4FJCA 1QDQA 3O1GA 1CQDA 3HHAA 2Y5BA 3CBJA 4OW0A 4YYUA 2AUXA 4I07A 2PREA 5JA7A 3PNRA 3S3QA 1MEMA 1YALA 3LXSA 3W31A 3KWBX 3U8EA 2AGAA 4YYQA 3V6EA 9PAPA 4PADA 3MTNA 3K8UA 2G6DA 3O65A 1ME3A 3N3KA 1MS6A 1X9YA 4W5BA 1PIPA 1EWOA 2E01A 4P6GA 2XU1A 4AXMA 1S4VA 4RF1A 4BOZA 2Z84A 4IP3A 3OQCA 4FIPA 2OP3A 2B1MA 5J94A 4GUAA 4N4ZA 3KX1A 5CHVA 2VHFA 2O6XA 3IMAA 2PBHA 4QRGA 1NB3A 4BS6A 3BOWA 1YZBA 1PE6A 2AU1A 3TMPA 1YT7A 1CB5A 4P16A 4RKXA 3CH2X 4HXDB 1YVBA 2G8JA 5CVMA 4YYRA 4KLBA 3RVXA 1U5IA 4N8WA 3TRKA 1F2BA 2E02A 2AUZA 2HXZA 2F1GA 1ATKA 1ME4A 2DCBA 1KHQA 2BU3A 3H8BA 3V6CA 1CTEA 1ITOA 1GECE 2CB5A 4CZWA 2JQGR 2XU4A 4BSQA 4FK5A 4XZXA 4I05A 3F5VA 2FQ9A 3BCNA 2BTWB 4REZA 3MHHA 3BC3A 3HWNA 1U9WA 4X6IA 1GMYA 2VHSA 3F75A 2DC8A 3IUTA 4MSXA 4OEMA 7PCKA 4IUMA 3KWZA 2NQAA 4MI7A 4OVZA 3WXGA 5A24A 1GLOA 3CH3X 1AYWA 1AU3A 4CDCB 1DEUA 3H89A 1PPDA 1IWDA 3P5XA 2FT2A 3HD3A 2JQFR 1EF7A 2DJFB 2HHNA 2FYEA 3HHIA 4ZTBA
chains in the Genus database with same CATH topology
4P6EA 2VFCA 4QBBA 2B1NA 3ERVA 5F02A 2YJBA 1HUCB 1W6FA 3RVVA 2AS8A 2DC9A 1AU4A 4RY2A 1QXPA 1MHWA 3S3RA 4Q8HA 4BGFA 3P5WA 5CVOB 1CV8A 2AIMA 1ZCMA 4PP2E 2C0YA 3ZUAA 1KXRA 2YJ8A 2XU3A 4I04A 1BGOA 2BSZA 1Q6KA 1PBHA 4DMXA 1SP4B 2OZ2A 3QT4A 4CDDB 2YJ2A 1CS8A 2R9OA 3USVA 4DMYA 2GHUA 2ATOA 3OF8A 2YJ9A 3MORA 2AYOA 3I06A 3KKUA 2R6NA 1F29A 1STFE 2FTDA 1CSBB 1E2TA 2IBIA 3C9EA 1AIMA 3K9MA 2R9NA 4GUZA 2FRAA 1PPNA 1GCBA 4ZUXU 2R9CA 4YYVA 2P86A 4HWYA 1MEGA 1AU2A 2AYNA 1TL9A 3CBKA 1A6RA 1DF0A 4MZSA 1NQCA 2DCAA 5EGWA 1NPZA 1EWLA 3D6SA 1AYVA 5EF4A 2FO5A 2NQDB 1CPJA 1U9VA 5CHTA 1K3BB 1QMYA 4MZOA 2H7JA 3B79A 3IHPA 1AU0A 2G8EA 3IV2A 3RVWA 3QJ3A 4YYSA 4YYWA 2ACTA 1MIRA 4BPVA 2DZZA 3BWKA 4NV8A 4W5CA 3KW9A 1VSNA 2VFBA 2E03A 1EWPA 3OF9A 3P5VA 2DCDA 2ARYA 1F2CA 3H7DA 4CDEB 2DZYA 3PW3A 3E1ZB 4QRXA 1CVZA 4K7CA 4XR7A 2R9MA 3N3GA 1TLOA 4QH6A 2G7YA 2BDLA 3PBHA 1O0EA 4YVAA 1YK8A 2PADA 1NB5A 2HH5A 2DCCA 2R9FA 3WXEA 2NQIA 4C5PA 4XUIA 4YV8A 3KFQA 3N4CA 3IEJA 3BPFA 5PADA 5K16A 3TNXA 4BQVA 3I3TA 3NHEA 1ICFA 2AVWA 4CDFB 5FPWA 2DC6A 3M99A 2YJCA 3MHSA 3KSEA 3O0UA 1FH0A 3P5UA 1YK7A 3H6SA 1KFXL 1F2AA 2E00A 1U9XA 1BY8A 4X6JA 1NL6A 2PNSA 3QSDA 2NQGA 3DF0A 1PXVA 4AXLA 1NLJA 2DJGB 2F7DA 1VJVA 2GFOA 1BP4A 6PADA 2P7UA 3LFYA 1AECA 1XKGA 5CVNB 1MDWA 3OISA 4PP1A 1PPPA 1EWMA 4W4UA 4G54A 3H8CA 1PCIA 2IPPB 1POPA 2FUDA 4N79A 1CJLA 1U9QX 1W4TA 1AYUA 1KHPA 4Q8GA 1KFUL 4PI3A 4WA6A 4QRVA 1TU6A 1Y08A 3GCBA 1ZIVA 2XU5A 3IOQA 3K24A 4X6HA 8PCHA 1BQIA 3OVZA 3AI8A 3WXFA 1W5RA 1PPOA 2HD5A 3BPMA 2BDZA 2FRQA 2Y6EA 1SNKA 1M6DA 2CIOA 5JH3A 4OELA 3D9WA 2WBFX 1THEA 3PDFA 1JQPA 2OULA 2DC7A 3OVXA 2P0RA 1Y4HA 4BS5A 1PADA 4B55A 1QOLA 4FJCA 1GX3A 1QDQA 3O1GA 1CQDA 3HHAA 2Y5BA 3CBJA 4YYUA 2AUXA 4I07A 2PREA 5JA7A 3PNRA 3S3QA 1MEMA 1YALA 3LXSA 3KWBX 3U8EA 4YYQA 3V6EA 9PAPA 4PADA 3MTNA 3K8UA 2G6DA 1ME3A 3N3KA 1MS6A 1X9YA 4W5BA 1PIPA 1EWOA 2E01A 4P6GA 2XU1A 4AXMA 1S4VA 4FIPA 2OP3A 2B1MA 5J94A 4N4ZA 3KX1A 5CHVA 2VHFA 2O6XA 3IMAA 2PBHA 4QRGA 1NB3A 4BS6A 3BOWA 1PE6A 2AU1A 1YT7A 1CB5A 3CH2X 1YVBA 2G8JA 5CVMA 4YYRA 4KLBA 3RVXA 1U5IA 4N8WA 1F2BA 2E02A 2AUZA 2HXZA 2F1GA 1ATKA 1ME4A 2DCBA 1KHQA 3LTWA 3H8BA 3V6CA 1CTEA 1ITOA 1GECE 2CB5A 4CZWA 2JQGR 2XU4A 4BSQA 4FK5A 4I05A 3F5VA 2FQ9A 3BCNA 3MHHA 4NV7A 3BC3A 3HWNA 1U9WA 4X6IA 1GMYA 2VHSA 3F75A 2DC8A 3IUTA 4MSXA 4OEMA 7PCKA 3KWZA 2NQAA 3WXGA 5A24A 1GLOA 3CH3X 1AYWA 1AU3A 4CDCB 1DEUA 3H89A 1PPDA 1IWDA 3P5XA 2FT2A 3HD3A 2JQFR 1EF7A 2DJFB 2HHNA 2FYEA 3HHIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P6E A;  4QBB A;  2B1N A;  3ERV A;  5F02 A;  2YJB A;  1HUC B;  3RVV A;  2AS8 A;  2DC9 A;  1AU4 A;  4RY2 A;  1QXP A;  1MHW A;  3S3R A;  4Q8H A;  3P5W A;  5CVO B;  1CV8 A;  2AIM A;  1ZCM A;  4PP2 E;  2C0Y A;  3ZUA A;  1KXR A;  2YJ8 A;  2XU3 A;  4I04 A;  1BGO A;  1Q6K A;  1PBH A;  4DMX A;  1SP4 B;  2OZ2 A;  3QT4 A;  4CDD B;  2YJ2 A;  1CS8 A;  2R9O A;  3USV A;  4DMY A;  2GHU A;  2ATO A;  3OF8 A;  2YJ9 A;  3MOR A;  2AYO A;  3I06 A;  3KKU A;  2R6N A;  1F29 A;  1STF E;  2FTD A;  1CSB B;  2IBI A;  3C9E A;  1AIM A;  3K9M A;  2R9N A;  2FRA A;  1PPN A;  1GCB A;  4ZUX U;  2R9C A;  4YYV A;  2P86 A;  4HWY A;  1MEG A;  1AU2 A;  2AYN A;  1TL9 A;  3CBK A;  1A6R A;  1DF0 A;  4MZS A;  1NQC A;  2DCA A;  5EGW A;  1NPZ A;  1EWL A;  3D6S A;  1AYV A;  5EF4 A;  2FO5 A;  2NQD B;  1CPJ A;  1U9V A;  5CHT A;  1K3B B;  1QMY A;  4MZO A;  2H7J A;  3B79 A;  3IHP A;  1AU0 A;  2G8E A;  3IV2 A;  3RVW A;  3QJ3 A;  4YYS A;  4YYW A;  2ACT A;  1MIR A;  4BPV A;  2DZZ A;  3BWK A;  4W5C A;  3KW9 A;  1VSN A;  2E03 A;  1EWP A;  3OF9 A;  3P5V A;  2DCD A;  2ARY A;  1F2C A;  3H7D A;  4CDE B;  2DZY A;  3PW3 A;  3E1Z B;  4QRX A;  1CVZ A;  4K7C A;  4XR7 A;  2R9M A;  3N3G A;  1TLO A;  4QH6 A;  2G7Y A;  2BDL A;  3PBH A;  1O0E A;  4YVA A;  1YK8 A;  2PAD A;  1NB5 A;  2HH5 A;  2DCC A;  2R9F A;  3WXE A;  2NQI A;  4XUI A;  4YV8 A;  3KFQ A;  3N4C A;  3IEJ A;  3BPF A;  5PAD A;  5K16 A;  3TNX A;  4BQV A;  3I3T A;  3NHE A;  1ICF A;  2AVW A;  4CDF B;  5FPW A;  2DC6 A;  3M99 A;  2YJC A;  3MHS A;  3KSE A;  3O0U A;  1FH0 A;  3P5U A;  1YK7 A;  3H6S A;  1KFX L;  1F2A A;  2E00 A;  1U9X A;  1BY8 A;  4X6J A;  1NL6 A;  2PNS A;  3QSD A;  2NQG A;  3DF0 A;  1PXV A;  4AXL A;  1NLJ A;  2DJG B;  2F7D A;  1VJV A;  2GFO A;  1BP4 A;  6PAD A;  2P7U A;  3LFY A;  1AEC A;  1XKG A;  5CVN B;  1MDW A;  3OIS A;  4PP1 A;  1PPP A;  1EWM A;  4W4U A;  4G54 A;  3H8C A;  1PCI A;  2IPP B;  1POP A;  2FUD A;  4N79 A;  1CJL A;  1U9Q X;  1AYU A;  1KHP A;  4Q8G A;  1KFU L;  4PI3 A;  4WA6 A;  4QRV A;  1TU6 A;  1Y08 A;  3GCB A;  1ZIV A;  2XU5 A;  3IOQ A;  3K24 A;  4X6H A;  8PCH A;  1BQI A;  3OVZ A;  3AI8 A;  3WXF A;  1PPO A;  2HD5 A;  3BPM A;  2BDZ A;  2FRQ A;  2Y6E A;  1SNK A;  1M6D A;  2CIO A;  5JH3 A;  4OEL A;  2WBF X;  1THE A;  3PDF A;  1JQP A;  2OUL A;  2DC7 A;  3OVX A;  2P0R A;  1Y4H A;  4BS5 A;  1PAD A;  1QOL A;  4FJC A;  1QDQ A;  3O1G A;  1CQD A;  3HHA A;  2Y5B A;  3CBJ A;  4YYU A;  2AUX A;  4I07 A;  2PRE A;  5JA7 A;  3PNR A;  3S3Q A;  1MEM A;  1YAL A;  3LXS A;  3KWB X;  3U8E A;  4YYQ A;  3V6E A;  9PAP A;  4PAD A;  3MTN A;  3K8U A;  2G6D A;  1ME3 A;  3N3K A;  1MS6 A;  1X9Y A;  4W5B A;  1PIP A;  1EWO A;  2E01 A;  4P6G A;  2XU1 A;  4AXM A;  1S4V A;  4FIP A;  2OP3 A;  2B1M A;  5J94 A;  4N4Z A;  3KX1 A;  5CHV A;  2VHF A;  2O6X A;  3IMA A;  2PBH A;  4QRG A;  1NB3 A;  4BS6 A;  3BOW A;  1PE6 A;  2AU1 A;  1YT7 A;  1CB5 A;  3CH2 X;  1YVB A;  2G8J A;  5CVM A;  4YYR A;  4KLB A;  3RVX A;  1U5I A;  4N8W A;  1F2B A;  2E02 A;  2AUZ A;  2HXZ A;  2F1G A;  1ATK A;  1ME4 A;  2DCB A;  1KHQ A;  3H8B A;  3V6C A;  1CTE A;  1ITO A;  1GEC E;  2CB5 A;  4CZW A;  2JQG R;  2XU4 A;  4BSQ A;  4FK5 A;  4I05 A;  3F5V A;  2FQ9 A;  3BCN A;  3MHH A;  3BC3 A;  3HWN A;  1U9W A;  4X6I A;  1GMY A;  2VHS A;  3F75 A;  2DC8 A;  3IUT A;  4MSX A;  4OEM A;  7PCK A;  3KWZ A;  2NQA A;  3WXG A;  5A24 A;  1GLO A;  3CH3 X;  1AYW A;  1AU3 A;  4CDC B;  1DEU A;  3H89 A;  1PPD A;  1IWD A;  3P5X A;  2FT2 A;  3HD3 A;  2JQF R;  1EF7 A;  2DJF B;  2HHN A;  2FYE A;  3HHI A; 
#chains in the Genus database with same CATH topology
 4P6E A;  4QBB A;  2B1N A;  3ERV A;  5F02 A;  3C0R A;  2YJB A;  3PRP A;  1HUC B;  3RVV A;  2AS8 A;  2DC9 A;  1AU4 A;  4RY2 A;  3IFU A;  1QXP A;  1MHW A;  3S3R A;  4Q8H A;  3P5W A;  5CVO B;  1CV8 A;  2AIM A;  5KO3 A;  1ZCM A;  4PP2 E;  3E9S A;  1DKI A;  2C0Y A;  3ZUA A;  1KXR A;  2YJ8 A;  2XU3 A;  4I04 A;  1BGO A;  2J7Q A;  1Q6K A;  1PBH A;  4DMX A;  1SP4 B;  2OZ2 A;  3QT4 A;  2J7Q C;  4CDD B;  2YJ2 A;  4BOP A;  1CS8 A;  2R9O A;  3USV A;  4DMY A;  2GHU A;  2ATO A;  3OF8 A;  2YJ9 A;  3MOR A;  2AYO A;  3I06 A;  3KKU A;  2R6N A;  1F29 A;  1STF E;  3PHX A;  2FTD A;  1CSB B;  2IBI A;  3C9E A;  1AIM A;  3K9M A;  2R9N A;  2FRA A;  1PPN A;  1GCB A;  4ZUX U;  4A5U A;  2R9C A;  2DOS A;  4YYV A;  2P86 A;  4HWY A;  4D8I A;  1MEG A;  1AU2 A;  2AYN A;  4M0W A;  1TL9 A;  3CBK A;  3ZNH A;  5EZQ A;  1A6R A;  1DF0 A;  4MZS A;  1NQC A;  2DCA A;  5EGW A;  1NPZ A;  1EWL A;  3D6S A;  1AYV A;  5EF4 A;  2FO5 A;  3PSE A;  2NQD B;  1CPJ A;  1U9V A;  5CHT A;  1K3B B;  1QMY A;  4MZO A;  4R3D A;  2H7J A;  3B79 A;  3IHP A;  1AU0 A;  2G8E A;  2BTW A;  3IV2 A;  3RVW A;  3QJ3 A;  4YYS A;  4YYW A;  3BB7 A;  2ACT A;  1MIR A;  4BPV A;  2DZZ A;  3BWK A;  4W5C A;  3KW9 A;  1VSN A;  2E03 A;  1EWP A;  3OF9 A;  3P5V A;  4BOS A;  4WUR A;  2DCD A;  2ARY A;  1F2C A;  3H7D A;  4BOQ A;  4CDE B;  2DZY A;  3PW3 A;  4D8B A;  3E1Z B;  1PVJ A;  4QRX A;  3PHU A;  1CVZ A;  3MP2 A;  4K7C A;  4XR7 A;  2R9M A;  3N3G A;  1TLO A;  4QH6 A;  5E6J A;  2G7Y A;  2BDL A;  3PBH A;  1O0E A;  4YVA A;  1YK8 A;  1UKF A;  2PAD A;  1NB5 A;  2HH5 A;  2JTC A;  3BBA A;  2DCC A;  2R9F A;  3WXE A;  2NQI A;  4XUI A;  4YV8 A;  3PHW A;  3KFQ A;  3N4C A;  3IEJ A;  3BPF A;  5PAD A;  5K16 A;  3TNX A;  4BQV A;  3I3T A;  3NHE A;  1ICF A;  2AVW A;  4CDF B;  4RNA A;  5FPW A;  2DC6 A;  3M99 A;  2YJC A;  3MHS A;  3KSE A;  3O0U A;  1FH0 A;  4RF0 A;  3P5U A;  1YK7 A;  3H6S A;  1KFX L;  3B21 A;  1F2A A;  2E00 A;  1U9X A;  1BY8 A;  4X6J A;  1NL6 A;  2PNS A;  3QSD A;  2NQG A;  4MM3 B;  3DF0 A;  1PXV A;  2FE8 A;  4AXL A;  1NLJ A;  2DJG B;  2F7D A;  1VJV A;  2GFO A;  1BP4 A;  6PAD A;  2P7U A;  3LFY A;  1AEC A;  1XKG A;  5CVN B;  3PRM A;  1MDW A;  3OIS A;  4PP1 A;  1PPP A;  1EWM A;  4W4U A;  4G54 A;  5EZS A;  3H8C A;  2HWK A;  3MJ5 A;  1PCI A;  2IPP B;  1POP A;  4PT5 A;  2FUD A;  3BY4 A;  4N79 A;  1CJL A;  1U9Q X;  1AYU A;  1KHP A;  4Q8G A;  1KFU L;  4BOU A;  4PI3 A;  4WA6 A;  4QRV A;  1TU6 A;  1Y08 A;  5JZE A;  3MTV A;  3GCB A;  1ZIV A;  2XU5 A;  3IOQ A;  3K24 A;  3RNV A;  4X6H A;  8PCH A;  1BQI A;  3OVZ A;  3AI8 A;  3WXF A;  4D8E A;  1PPO A;  3W30 A;  2HD5 A;  3BPM A;  2BDZ A;  3PT2 A;  2FRQ A;  4OVZ B;  2UZJ A;  2Y6E A;  1SNK A;  1M6D A;  2CIO A;  5JH3 A;  4OEL A;  2WBF X;  1THE A;  3PDF A;  1JQP A;  2JRI A;  2OUL A;  2DC7 A;  3OVX A;  2P0R A;  1Y4H A;  4BS5 A;  1PAD A;  1QOL A;  4FJC A;  1QDQ A;  3O1G A;  1CQD A;  3HHA A;  2Y5B A;  3CBJ A;  4OW0 A;  4YYU A;  2AUX A;  4I07 A;  2PRE A;  5JA7 A;  3PNR A;  3S3Q A;  1MEM A;  1YAL A;  3LXS A;  3W31 A;  3KWB X;  3U8E A;  2AGA A;  4YYQ A;  3V6E A;  9PAP A;  4PAD A;  3MTN A;  3K8U A;  2G6D A;  3O65 A;  1ME3 A;  3N3K A;  1MS6 A;  1X9Y A;  4W5B A;  1PIP A;  1EWO A;  2E01 A;  4P6G A;  2XU1 A;  4AXM A;  1S4V A;  4RF1 A;  4BOZ A;  2Z84 A;  4IP3 A;  3OQC A;  4FIP A;  2OP3 A;  2B1M A;  5J94 A;  4GUA A;  4N4Z A;  3KX1 A;  5CHV A;  2VHF A;  2O6X A;  3IMA A;  2PBH A;  4QRG A;  1NB3 A;  4BS6 A;  3BOW A;  1YZB A;  1PE6 A;  2AU1 A;  3TMP A;  1YT7 A;  1CB5 A;  4P16 A;  4RKX A;  3CH2 X;  4HXD B;  1YVB A;  2G8J A;  5CVM A;  4YYR A;  4KLB A;  3RVX A;  1U5I A;  4N8W A;  3TRK A;  1F2B A;  2E02 A;  2AUZ A;  2HXZ A;  2F1G A;  1ATK A;  1ME4 A;  2DCB A;  1KHQ A;  2BU3 A;  3H8B A;  3V6C A;  1CTE A;  1ITO A;  1GEC E;  2CB5 A;  4CZW A;  2JQG R;  2XU4 A;  4BSQ A;  4FK5 A;  4XZX A;  4I05 A;  3F5V A;  2FQ9 A;  3BCN A;  2BTW B;  4REZ A;  3MHH A;  3BC3 A;  3HWN A;  1U9W A;  4X6I A;  1GMY A;  2VHS A;  3F75 A;  2DC8 A;  3IUT A;  4MSX A;  4OEM A;  7PCK A;  4IUM A;  3KWZ A;  2NQA A;  4MI7 A;  4OVZ A;  3WXG A;  5A24 A;  1GLO A;  3CH3 X;  1AYW A;  1AU3 A;  4CDC B;  1DEU A;  3H89 A;  1PPD A;  1IWD A;  3P5X A;  2FT2 A;  3HD3 A;  2JQF R;  1EF7 A;  2DJF B;  2HHN A;  2FYE A;  3HHI A;  4ZTB A; 
#chains in the Genus database with same CATH homology
 4P6E A;  2VFC A;  4QBB A;  2B1N A;  3ERV A;  5F02 A;  2YJB A;  1HUC B;  1W6F A;  3RVV A;  2AS8 A;  2DC9 A;  1AU4 A;  4RY2 A;  1QXP A;  1MHW A;  3S3R A;  4Q8H A;  4BGF A;  3P5W A;  5CVO B;  1CV8 A;  2AIM A;  1ZCM A;  4PP2 E;  2C0Y A;  3ZUA A;  1KXR A;  2YJ8 A;  2XU3 A;  4I04 A;  1BGO A;  2BSZ A;  1Q6K A;  1PBH A;  4DMX A;  1SP4 B;  2OZ2 A;  3QT4 A;  4CDD B;  2YJ2 A;  1CS8 A;  2R9O A;  3USV A;  4DMY A;  2GHU A;  2ATO A;  3OF8 A;  2YJ9 A;  3MOR A;  2AYO A;  3I06 A;  3KKU A;  2R6N A;  1F29 A;  1STF E;  2FTD A;  1CSB B;  1E2T A;  2IBI A;  3C9E A;  1AIM A;  3K9M A;  2R9N A;  4GUZ A;  2FRA A;  1PPN A;  1GCB A;  4ZUX U;  2R9C A;  4YYV A;  2P86 A;  4HWY A;  1MEG A;  1AU2 A;  2AYN A;  1TL9 A;  3CBK A;  1A6R A;  1DF0 A;  4MZS A;  1NQC A;  2DCA A;  5EGW A;  1NPZ A;  1EWL A;  3D6S A;  1AYV A;  5EF4 A;  2FO5 A;  2NQD B;  1CPJ A;  1U9V A;  5CHT A;  1K3B B;  1QMY A;  4MZO A;  2H7J A;  3B79 A;  3IHP A;  1AU0 A;  2G8E A;  3IV2 A;  3RVW A;  3QJ3 A;  4YYS A;  4YYW A;  2ACT A;  1MIR A;  4BPV A;  2DZZ A;  3BWK A;  4NV8 A;  4W5C A;  3KW9 A;  1VSN A;  2VFB A;  2E03 A;  1EWP A;  3OF9 A;  3P5V A;  2DCD A;  2ARY A;  1F2C A;  3H7D A;  4CDE B;  2DZY A;  3PW3 A;  3E1Z B;  4QRX A;  1CVZ A;  4K7C A;  4XR7 A;  2R9M A;  3N3G A;  1TLO A;  4QH6 A;  2G7Y A;  2BDL A;  3PBH A;  1O0E A;  4YVA A;  1YK8 A;  2PAD A;  1NB5 A;  2HH5 A;  2DCC A;  2R9F A;  3WXE A;  2NQI A;  4C5P A;  4XUI A;  4YV8 A;  3KFQ A;  3N4C A;  3IEJ A;  3BPF A;  5PAD A;  5K16 A;  3TNX A;  4BQV A;  3I3T A;  3NHE A;  1ICF A;  2AVW A;  4CDF B;  5FPW A;  2DC6 A;  3M99 A;  2YJC A;  3MHS A;  3KSE A;  3O0U A;  1FH0 A;  3P5U A;  1YK7 A;  3H6S A;  1KFX L;  1F2A A;  2E00 A;  1U9X A;  1BY8 A;  4X6J A;  1NL6 A;  2PNS A;  3QSD A;  2NQG A;  3DF0 A;  1PXV A;  4AXL A;  1NLJ A;  2DJG B;  2F7D A;  1VJV A;  2GFO A;  1BP4 A;  6PAD A;  2P7U A;  3LFY A;  1AEC A;  1XKG A;  5CVN B;  1MDW A;  3OIS A;  4PP1 A;  1PPP A;  1EWM A;  4W4U A;  4G54 A;  3H8C A;  1PCI A;  2IPP B;  1POP A;  2FUD A;  4N79 A;  1CJL A;  1U9Q X;  1W4T A;  1AYU A;  1KHP A;  4Q8G A;  1KFU L;  4PI3 A;  4WA6 A;  4QRV A;  1TU6 A;  1Y08 A;  3GCB A;  1ZIV A;  2XU5 A;  3IOQ A;  3K24 A;  4X6H A;  8PCH A;  1BQI A;  3OVZ A;  3AI8 A;  3WXF A;  1W5R A;  1PPO A;  2HD5 A;  3BPM A;  2BDZ A;  2FRQ A;  2Y6E A;  1SNK A;  1M6D A;  2CIO A;  5JH3 A;  4OEL A;  3D9W A;  2WBF X;  1THE A;  3PDF A;  1JQP A;  2OUL A;  2DC7 A;  3OVX A;  2P0R A;  1Y4H A;  4BS5 A;  1PAD A;  4B55 A;  1QOL A;  4FJC A;  1GX3 A;  1QDQ A;  3O1G A;  1CQD A;  3HHA A;  2Y5B A;  3CBJ A;  4YYU A;  2AUX A;  4I07 A;  2PRE A;  5JA7 A;  3PNR A;  3S3Q A;  1MEM A;  1YAL A;  3LXS A;  3KWB X;  3U8E A;  4YYQ A;  3V6E A;  9PAP A;  4PAD A;  3MTN A;  3K8U A;  2G6D A;  1ME3 A;  3N3K A;  1MS6 A;  1X9Y A;  4W5B A;  1PIP A;  1EWO A;  2E01 A;  4P6G A;  2XU1 A;  4AXM A;  1S4V A;  4FIP A;  2OP3 A;  2B1M A;  5J94 A;  4N4Z A;  3KX1 A;  5CHV A;  2VHF A;  2O6X A;  3IMA A;  2PBH A;  4QRG A;  1NB3 A;  4BS6 A;  3BOW A;  1PE6 A;  2AU1 A;  1YT7 A;  1CB5 A;  3CH2 X;  1YVB A;  2G8J A;  5CVM A;  4YYR A;  4KLB A;  3RVX A;  1U5I A;  4N8W A;  1F2B A;  2E02 A;  2AUZ A;  2HXZ A;  2F1G A;  1ATK A;  1ME4 A;  2DCB A;  1KHQ A;  3LTW A;  3H8B A;  3V6C A;  1CTE A;  1ITO A;  1GEC E;  2CB5 A;  4CZW A;  2JQG R;  2XU4 A;  4BSQ A;  4FK5 A;  4I05 A;  3F5V A;  2FQ9 A;  3BCN A;  3MHH A;  4NV7 A;  3BC3 A;  3HWN A;  1U9W A;  4X6I A;  1GMY A;  2VHS A;  3F75 A;  2DC8 A;  3IUT A;  4MSX A;  4OEM A;  7PCK A;  3KWZ A;  2NQA A;  3WXG A;  5A24 A;  1GLO A;  3CH3 X;  1AYW A;  1AU3 A;  4CDC B;  1DEU A;  3H89 A;  1PPD A;  1IWD A;  3P5X A;  2FT2 A;  3HD3 A;  2JQF R;  1EF7 A;  2DJF B;  2HHN A;  2FYE A;  3HHI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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