2DCCA

X-ray crystal structure analysis of bovine spleen cathepsin b-ca077 complex
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
253
structure length
251
Chain Sequence
LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCGIESEIVAGMPCT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Quantitative estimation of each active subsite of cathepsin B for the inhibitory activity, based on the inhibitory activitybinding mode relationship of a series of epoxysuccinyl inhibitors by X-ray crystal structure analyses of the complexes
rcsb
molecule tags Hydrolase
molecule keywords CATHEPSIN B
total genus 75
structure length 251
sequence length 253
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2006-01-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2dccA00
1KXRA 2DZZA 2E00A 1CS8A 5CHTA 3OF8A 1SP4B 2JQGR 1MIRA 1PBHA 1AIMA 1DF0A 4CDEB 1O0EA 2DZYA 3USVA 1X9YA 3QJ3A 1MEGA 1QOLA 1GLOA 1HUCB 3P5XA 2DJGB 1MEMA 2WBFX 1POPA 4KLBA 1TL9A 2DCCA 3MORA 1NL6A 5JA7A 5JH3A 3V6CA 2AYNA 3F75A 1YT7A 2F7DA 3RVVA 3PDFA 1AU4A 3KSEA 4N79A 4N8WA 4W5BA 4BPVA 4P6EA 2R9MA 1KFXL 2PREA 1CB5A 3IEJA 3K8UA 1KFUL 4G54A 4X6JA 3MHSA 3C9EA 2PADA 5F02A 1CVZA 1ATKA 2GFOA 3B79A 1EWMA 2NQIA 3OISA 2DC8A 3GCBA 4BS6A 1U5IA 4XUIA 2E03A 2CB5A 1PPNA 1K3BB 1CJLA 2BDLA 1DEUA 1GECE 4QH6A 4RY2A 2FUDA 4FK5A 2AUXA 3WXGA 3HWNA 3S3RA 4X6HA 2BDZA 4ZUXU 2CIOA 3TNXA 2R9OA 3IMAA 3HHAA 3S3QA 4YYRA 2R6NA 4BQVA 3H89A 1STFE 4MZSA 2C0YA 1AECA 1YK8A 4AXLA 2DC9A 1YALA 3BWKA 4W4UA 3PBHA 4MSXA 2R9NA 1ICFA 3CH2X 4I04A 4I07A 1U9WA 1NB3A 3O0UA 2FT2A 1S4VA 3KKUA 1MS6A 2FTDA 1U9VA 4CDFB 4QRGA 1M6DA 7PCKA 1AU2A 1F29A 3WXEA 4OEMA 2AU1A 5K16A 1AU3A 2FRAA 2NQDB 3WXFA 3V6EA 2DCDA 1F2AA 1NQCA 2AS8A 3QSDA 2B1MA 3N3GA 2XU5A 3RVWA 5A24A 1MDWA 4XR7A 1EF7A 6PADA 4FIPA 1CPJA 2R9CA 3H8CA 1NB5A 3ERVA 3P5UA 3BPMA 3M99A 4BSQA 4Q8GA 3N3KA 2NQGA 2ATOA 2YJ8A 1A6RA 2PBHA 1TLOA 4Q8HA 1MHWA 4FJCA 2PNSA 1AYVA 2AVWA 1ME4A 4MZOA 1KHPA 2JQFR 5CVMA 2DCBA 2FO5A 3H7DA 4QBBA 1VSNA 4CDCB 2G8JA 2OZ2A 1PADA 4BS5A 3CH3X 4P6GA 2E01A 1CV8A 3HHIA 3KWZA 3CBKA 4N4ZA 3D6SA 3E1ZB 1YVBA 4WA6A 1XKGA 3ZUAA 4AXMA 1PE6A 2AYOA 2P7UA 2ACTA 3P5WA 1ME3A 4QRVA 2YJ2A 1YK7A 1F2CA 2DJFB 3IOQA 1NPZA 4DMYA 4DMXA 1PPPA 3NHEA 1TU6A 3AI8A 2DCAA 4OELA 3LFYA 4CZWA 3KWBX 4QRXA 1ITOA 3P5VA 4W5CA 1SNKA 3BOWA 4CDDB 3BC3A 2AUZA 2FYEA 1PXVA 2DC7A 3K9MA 3MHHA 2G8EA 1CQDA 1QDQA 1AYWA 1JQPA 1CSBB 5EGWA 2YJ9A 1Q6KA 4PP1A 4HWYA 2OP3A 2XU1A 4YYVA 2XU3A 4YYSA 2Y5BA 5CVOB 1PPDA 4YYWA 1BGOA 2P86A 1Y08A 2Y6EA 3O1GA 1BQIA 9PAPA 5EF4A 1U9XA 1AYUA 1PIPA 2IPPB 2XU4A 1F2BA 1KHQA 3KFQA 2VHSA 1Y4HA 3PW3A 2HD5A 3H8BA 1GCBA 4PADA 2OULA 3HD3A 4PP2E 2F1GA 1EWOA 2R9FA 2HXZA 2FRQA 2FQ9A 1BY8A 5CHVA 1EWPA 4YYQA 3H6SA 3I06A 4K7CA 4PI3A 3DF0A 1IWDA 3F5VA 1ZCMA 3KX1A 2G7YA 2NQAA 3LXSA 3N4CA 2DC6A 5CVNB 1EWLA 3BPFA 1NLJA 2VHFA 3IV2A 2ARYA 8PCHA 1U9QX 1ZIVA 2H7JA 3IHPA 1PPOA 3OVXA 4YV8A 2G6DA 1VJVA 5J94A 2O6XA 1THEA 2IBIA 3OF9A 4I05A 1PCIA 1QMYA 1QXPA 3OVZA 2P0RA 3K24A 1FH0A 3QT4A 5FPWA 2AIMA 3I3TA 3RVXA 2HH5A 2HHNA 1GMYA 2B1NA 2E02A 2YJCA 1AU0A 5PADA 1BP4A 3MTNA 3BCNA 4X6IA 3IUTA 3KW9A 1CTEA 3PNRA 4YYUA 4YVAA 3CBJA 3U8EA 2GHUA 2YJBA
chains in the Genus database with same CATH superfamily
3PRPA 1KXRA 2DZZA 2E00A 1CS8A 5CHTA 3OF8A 1SP4B 2JQGR 1MIRA 1PBHA 1AIMA 1DF0A 4CDEB 1O0EA 2DZYA 3USVA 1X9YA 3QJ3A 1MEGA 1QOLA 5KO3A 2BU3A 1GLOA 1HUCB 3P5XA 2DJGB 1MEMA 2WBFX 1POPA 4KLBA 4MM3B 1TL9A 2DCCA 3MORA 1NL6A 5JA7A 5JH3A 3V6CA 2AYNA 3F75A 3MJ5A 1YT7A 4XZXA 2F7DA 3RVVA 2JRIA 3PDFA 1AU4A 3KSEA 4N79A 4N8WA 4RKXA 4W5BA 4BPVA 4P6EA 4HXDB 2R9MA 1KFXL 2PREA 4BOQA 4R3DA 1CB5A 3IEJA 4ZTBA 3K8UA 1KFUL 4G54A 4X6JA 3MHSA 3C9EA 2PADA 5F02A 5EZQA 1CVZA 1ATKA 2GFOA 4IUMA 3B79A 3RNVA 1EWMA 2NQIA 1UKFA 3OISA 2HWKA 2DC8A 3GCBA 4BS6A 1U5IA 4XUIA 2E03A 2CB5A 1PPNA 1K3BB 1CJLA 2BDLA 4D8IA 1DEUA 1GECE 4QH6A 2UZJA 4REZA 2J7QA 4RY2A 2FUDA 4FK5A 2AUXA 3WXGA 3HWNA 3S3RA 4X6HA 2BDZA 4ZUXU 2CIOA 3TNXA 1DKIA 2R9OA 3IMAA 3HHAA 3S3QA 4YYRA 2R6NA 4BQVA 4WURA 3H89A 1STFE 4MZSA 2C0YA 1AECA 1YK8A 4AXLA 2DC9A 1YALA 3BWKA 3PT2A 4W4UA 3PBHA 4MSXA 2R9NA 1ICFA 3W31A 3CH2X 4I04A 4RF0A 4I07A 1U9WA 1NB3A 3O0UA 2FT2A 1S4VA 3KKUA 1MS6A 2FTDA 1U9VA 4CDFB 4QRGA 1M6DA 7PCKA 5E6JA 1AU2A 1F29A 3WXEA 4OEMA 2AU1A 5K16A 1AU3A 2FRAA 2NQDB 3WXFA 3V6EA 2DCDA 1F2AA 1NQCA 2AS8A 3QSDA 2B1MA 3MTVA 3N3GA 2XU5A 3RVWA 5A24A 1MDWA 4XR7A 1EF7A 6PADA 3PHWA 4FIPA 1CPJA 3C0RA 4OVZB 4BOPA 2R9CA 3H8CA 1NB5A 3P5UA 3ERVA 3BPMA 3M99A 4BSQA 4Q8GA 3N3KA 2NQGA 2ATOA 2YJ8A 1A6RA 2PBHA 1TLOA 4Q8HA 1MHWA 4FJCA 2PNSA 1AYVA 2AVWA 1ME4A 3BBAA 3BB7A 4MZOA 1KHPA 2JQFR 5CVMA 2DCBA 2FO5A 3H7DA 4QBBA 1VSNA 4CDCB 2G8JA 2OZ2A 1PADA 4BS5A 4GUAA 3CH3X 4P6GA 1PVJA 4RF1A 2E01A 1CV8A 3HHIA 3KWZA 3CBKA 3B21A 4OW0A 3TMPA 4N4ZA 3D6SA 4M0WA 3E1ZB 1YVBA 4WA6A 4BOSA 2BTWB 1XKGA 2Z84A 3IFUA 3ZUAA 3OQCA 4AXMA 1PE6A 2AYOA 5JZEA 2P7UA 2ACTA 4P16A 3P5WA 1ME3A 4QRVA 2YJ2A 1YK7A 1F2CA 2DJFB 3IOQA 1NPZA 4DMYA 4DMXA 1PPPA 3NHEA 1YZBA 1TU6A 3E9SA 3AI8A 2DCAA 4OELA 3LFYA 4CZWA 3KWBX 1ITOA 4QRXA 3P5VA 3PHXA 4W5CA 1SNKA 3BOWA 4CDDB 3BC3A 4A5UA 2AUZA 2FYEA 1PXVA 2DC7A 3K9MA 3MHHA 2G8EA 1CQDA 1QDQA 1AYWA 1JQPA 1CSBB 5EGWA 3BY4A 2YJ9A 4BOZA 1Q6KA 4PP1A 4HWYA 2OP3A 2XU1A 4YYVA 2XU3A 4YYSA 2Y5BA 5CVOB 1PPDA 4YYWA 1BGOA 4PT5A 2P86A 1Y08A 2Y6EA 3O1GA 1BQIA 9PAPA 5EF4A 1U9XA 1AYUA 1PIPA 2IPPB 2XU4A 4BOUA 1F2BA 1KHQA 3ZNHA 3KFQA 2VHSA 1Y4HA 3PW3A 2HD5A 3H8BA 1GCBA 4PADA 2OULA 3HD3A 4PP2E 2F1GA 1EWOA 2R9FA 2HXZA 2FRQA 2FQ9A 1BY8A 5CHVA 4OVZA 1EWPA 2JTCA 3MP2A 4YYQA 3H6SA 3I06A 4K7CA 4PI3A 2J7QC 3DF0A 2AGAA 1IWDA 3F5VA 1ZCMA 3KX1A 2G7YA 2NQAA 3LXSA 3N4CA 2DC6A 3PHUA 5CVNB 2FE8A 1EWLA 3BPFA 1NLJA 2VHFA 3IV2A 2ARYA 8PCHA 4MI7A 1U9QX 1ZIVA 2H7JA 3IHPA 1PPOA 3OVXA 3PSEA 4YV8A 2DOSA 2G6DA 1VJVA 5J94A 2O6XA 1THEA 2IBIA 3OF9A 4I05A 1PCIA 3O65A 1QMYA 1QXPA 3OVZA 2P0RA 3K24A 4IP3A 1FH0A 3QT4A 5FPWA 2AIMA 3I3TA 2BTWA 3RVXA 4D8EA 4RNAA 2HH5A 2HHNA 1GMYA 2B1NA 2E02A 3W30A 2YJCA 1AU0A 5PADA 1BP4A 5EZSA 3MTNA 3BCNA 4X6IA 3IUTA 3KW9A 3PRMA 4D8BA 1CTEA 3PNRA 4YYUA 4YVAA 3CBJA 3U8EA 2GHUA 3TRKA 2YJBA
chains in the Genus database with same CATH topology
1KXRA 2DZZA 2E00A 1CS8A 5CHTA 3OF8A 1SP4B 2JQGR 1MIRA 4NV8A 1PBHA 1AIMA 1DF0A 4CDEB 1O0EA 2DZYA 3USVA 1X9YA 3QJ3A 1MEGA 1QOLA 4BGFA 1GLOA 1HUCB 3P5XA 2DJGB 1MEMA 2WBFX 1POPA 4KLBA 1TL9A 2DCCA 3MORA 2BSZA 1NL6A 5JA7A 5JH3A 3V6CA 2AYNA 3F75A 1YT7A 2F7DA 3RVVA 3PDFA 1AU4A 3KSEA 4N79A 4N8WA 4W5BA 4BPVA 4P6EA 2R9MA 1KFXL 2PREA 1CB5A 3IEJA 3K8UA 1KFUL 4G54A 4X6JA 3MHSA 3C9EA 2PADA 5F02A 1CVZA 1ATKA 2GFOA 3B79A 1EWMA 2NQIA 3OISA 2DC8A 3GCBA 4BS6A 1U5IA 4XUIA 2E03A 2CB5A 1PPNA 1K3BB 1CJLA 2BDLA 1DEUA 1GECE 4QH6A 4RY2A 2FUDA 4FK5A 2AUXA 3WXGA 3HWNA 3S3RA 4X6HA 2BDZA 4ZUXU 2CIOA 3TNXA 2R9OA 3IMAA 3HHAA 3S3QA 4YYRA 2R6NA 4BQVA 3H89A 1STFE 4MZSA 2C0YA 1AECA 1YK8A 4AXLA 2DC9A 1YALA 3BWKA 4W4UA 3PBHA 4MSXA 2R9NA 1ICFA 3CH2X 4I04A 4I07A 1U9WA 1NB3A 3O0UA 2FT2A 1S4VA 3KKUA 1MS6A 2FTDA 1U9VA 4CDFB 4QRGA 1M6DA 7PCKA 1AU2A 1F29A 3WXEA 4OEMA 2AU1A 5K16A 1AU3A 2FRAA 2NQDB 3WXFA 3V6EA 2DCDA 1F2AA 1NQCA 2AS8A 3QSDA 2B1MA 3N3GA 2XU5A 3RVWA 5A24A 1MDWA 4XR7A 1EF7A 6PADA 4FIPA 1CPJA 2R9CA 3H8CA 1NB5A 3ERVA 3P5UA 3BPMA 3M99A 4BSQA 4Q8GA 3N3KA 2NQGA 2ATOA 2YJ8A 1A6RA 2PBHA 1TLOA 4Q8HA 1MHWA 4FJCA 2PNSA 1AYVA 2AVWA 1ME4A 4MZOA 1KHPA 1GX3A 2JQFR 5CVMA 2DCBA 2FO5A 3H7DA 4QBBA 1VSNA 4CDCB 2G8JA 2OZ2A 1PADA 4BS5A 3CH3X 4B55A 4P6GA 2E01A 1CV8A 3HHIA 3KWZA 3CBKA 4GUZA 4N4ZA 3D6SA 3E1ZB 1YVBA 4WA6A 1XKGA 3ZUAA 4AXMA 1PE6A 2AYOA 2P7UA 2ACTA 3P5WA 1ME3A 4QRVA 4NV7A 2YJ2A 1YK7A 1F2CA 2DJFB 3IOQA 1NPZA 4DMYA 4DMXA 1PPPA 3NHEA 3D9WA 1W6FA 1TU6A 3AI8A 2DCAA 4OELA 3LFYA 4CZWA 3KWBX 1ITOA 4QRXA 3P5VA 4W5CA 1SNKA 3BOWA 4CDDB 3BC3A 2AUZA 2FYEA 1PXVA 2DC7A 3K9MA 3MHHA 2G8EA 1CQDA 1QDQA 1AYWA 1JQPA 1CSBB 5EGWA 1W5RA 2YJ9A 1Q6KA 4PP1A 4HWYA 2OP3A 2XU1A 4YYVA 2XU3A 4YYSA 2Y5BA 5CVOB 1PPDA 4YYWA 1BGOA 2P86A 1Y08A 2Y6EA 3O1GA 1BQIA 9PAPA 5EF4A 1U9XA 1AYUA 1PIPA 2VFCA 2IPPB 2XU4A 1F2BA 1KHQA 1W4TA 3KFQA 2VHSA 1Y4HA 3PW3A 2HD5A 3H8BA 1GCBA 4PADA 2OULA 3HD3A 4PP2E 2F1GA 1EWOA 2R9FA 2HXZA 2FRQA 2FQ9A 1BY8A 5CHVA 1EWPA 4YYQA 3H6SA 3I06A 4K7CA 4PI3A 3DF0A 1IWDA 3F5VA 1ZCMA 3KX1A 2G7YA 2NQAA 3LXSA 3N4CA 2DC6A 5CVNB 1EWLA 3BPFA 1NLJA 2VHFA 3IV2A 2ARYA 8PCHA 1U9QX 1ZIVA 2H7JA 3IHPA 1PPOA 3OVXA 4YV8A 2G6DA 1VJVA 5J94A 2O6XA 1THEA 2IBIA 3OF9A 4I05A 1PCIA 3LTWA 1QMYA 1QXPA 3OVZA 2P0RA 1E2TA 3K24A 1FH0A 3QT4A 5FPWA 2AIMA 3I3TA 4C5PA 3RVXA 2HH5A 2HHNA 1GMYA 2B1NA 2E02A 2YJCA 1AU0A 5PADA 1BP4A 3MTNA 3BCNA 4X6IA 3IUTA 3KW9A 2VFBA 1CTEA 3PNRA 4YYUA 4YVAA 3CBJA 3U8EA 2GHUA 2YJBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KXR A;  2DZZ A;  2E00 A;  1CS8 A;  5CHT A;  3OF8 A;  1SP4 B;  2JQG R;  1MIR A;  1PBH A;  1AIM A;  1DF0 A;  4CDE B;  1O0E A;  2DZY A;  3USV A;  1X9Y A;  3QJ3 A;  1MEG A;  1QOL A;  1GLO A;  1HUC B;  3P5X A;  2DJG B;  1MEM A;  2WBF X;  1POP A;  4KLB A;  1TL9 A;  2DCC A;  3MOR A;  1NL6 A;  5JA7 A;  5JH3 A;  3V6C A;  2AYN A;  3F75 A;  1YT7 A;  2F7D A;  3RVV A;  3PDF A;  1AU4 A;  3KSE A;  4N79 A;  4N8W A;  4W5B A;  4BPV A;  4P6E A;  2R9M A;  1KFX L;  2PRE A;  1CB5 A;  3IEJ A;  3K8U A;  1KFU L;  4G54 A;  4X6J A;  3MHS A;  3C9E A;  2PAD A;  5F02 A;  1CVZ A;  1ATK A;  2GFO A;  3B79 A;  1EWM A;  2NQI A;  3OIS A;  2DC8 A;  3GCB A;  4BS6 A;  1U5I A;  4XUI A;  2E03 A;  2CB5 A;  1PPN A;  1K3B B;  1CJL A;  2BDL A;  1DEU A;  1GEC E;  4QH6 A;  4RY2 A;  2FUD A;  4FK5 A;  2AUX A;  3WXG A;  3HWN A;  3S3R A;  4X6H A;  2BDZ A;  4ZUX U;  2CIO A;  3TNX A;  2R9O A;  3IMA A;  3HHA A;  3S3Q A;  4YYR A;  2R6N A;  4BQV A;  3H89 A;  1STF E;  4MZS A;  2C0Y A;  1AEC A;  1YK8 A;  4AXL A;  2DC9 A;  1YAL A;  3BWK A;  4W4U A;  3PBH A;  4MSX A;  2R9N A;  1ICF A;  3CH2 X;  4I04 A;  4I07 A;  1U9W A;  1NB3 A;  3O0U A;  2FT2 A;  1S4V A;  3KKU A;  1MS6 A;  2FTD A;  1U9V A;  4CDF B;  4QRG A;  1M6D A;  7PCK A;  1AU2 A;  1F29 A;  3WXE A;  4OEM A;  2AU1 A;  5K16 A;  1AU3 A;  2FRA A;  2NQD B;  3WXF A;  3V6E A;  2DCD A;  1F2A A;  1NQC A;  2AS8 A;  3QSD A;  2B1M A;  3N3G A;  2XU5 A;  3RVW A;  5A24 A;  1MDW A;  4XR7 A;  1EF7 A;  6PAD A;  4FIP A;  1CPJ A;  2R9C A;  3H8C A;  1NB5 A;  3ERV A;  3P5U A;  3BPM A;  3M99 A;  4BSQ A;  4Q8G A;  3N3K A;  2NQG A;  2ATO A;  2YJ8 A;  1A6R A;  2PBH A;  1TLO A;  4Q8H A;  1MHW A;  4FJC A;  2PNS A;  1AYV A;  2AVW A;  1ME4 A;  4MZO A;  1KHP A;  2JQF R;  5CVM A;  2DCB A;  2FO5 A;  3H7D A;  4QBB A;  1VSN A;  4CDC B;  2G8J A;  2OZ2 A;  1PAD A;  4BS5 A;  3CH3 X;  4P6G A;  2E01 A;  1CV8 A;  3HHI A;  3KWZ A;  3CBK A;  4N4Z A;  3D6S A;  3E1Z B;  1YVB A;  4WA6 A;  1XKG A;  3ZUA A;  4AXM A;  1PE6 A;  2AYO A;  2P7U A;  2ACT A;  3P5W A;  1ME3 A;  4QRV A;  2YJ2 A;  1YK7 A;  1F2C A;  2DJF B;  3IOQ A;  1NPZ A;  4DMY A;  4DMX A;  1PPP A;  3NHE A;  1TU6 A;  3AI8 A;  2DCA A;  4OEL A;  3LFY A;  4CZW A;  3KWB X;  4QRX A;  1ITO A;  3P5V A;  4W5C A;  1SNK A;  3BOW A;  4CDD B;  3BC3 A;  2AUZ A;  2FYE A;  1PXV A;  2DC7 A;  3K9M A;  3MHH A;  2G8E A;  1CQD A;  1QDQ A;  1AYW A;  1JQP A;  1CSB B;  5EGW A;  2YJ9 A;  1Q6K A;  4PP1 A;  4HWY A;  2OP3 A;  2XU1 A;  4YYV A;  2XU3 A;  4YYS A;  2Y5B A;  5CVO B;  1PPD A;  4YYW A;  1BGO A;  2P86 A;  1Y08 A;  2Y6E A;  3O1G A;  1BQI A;  9PAP A;  5EF4 A;  1U9X A;  1AYU A;  1PIP A;  2IPP B;  2XU4 A;  1F2B A;  1KHQ A;  3KFQ A;  2VHS A;  1Y4H A;  3PW3 A;  2HD5 A;  3H8B A;  1GCB A;  4PAD A;  2OUL A;  3HD3 A;  4PP2 E;  2F1G A;  1EWO A;  2R9F A;  2HXZ A;  2FRQ A;  2FQ9 A;  1BY8 A;  5CHV A;  1EWP A;  4YYQ A;  3H6S A;  3I06 A;  4K7C A;  4PI3 A;  3DF0 A;  1IWD A;  3F5V A;  1ZCM A;  3KX1 A;  2G7Y A;  2NQA A;  3LXS A;  3N4C A;  2DC6 A;  5CVN B;  1EWL A;  3BPF A;  1NLJ A;  2VHF A;  3IV2 A;  2ARY A;  8PCH A;  1U9Q X;  1ZIV A;  2H7J A;  3IHP A;  1PPO A;  3OVX A;  4YV8 A;  2G6D A;  1VJV A;  5J94 A;  2O6X A;  1THE A;  2IBI A;  3OF9 A;  4I05 A;  1PCI A;  1QMY A;  1QXP A;  3OVZ A;  2P0R A;  3K24 A;  1FH0 A;  3QT4 A;  5FPW A;  2AIM A;  3I3T A;  3RVX A;  2HH5 A;  2HHN A;  1GMY A;  2B1N A;  2E02 A;  2YJC A;  1AU0 A;  5PAD A;  1BP4 A;  3MTN A;  3BCN A;  4X6I A;  3IUT A;  3KW9 A;  1CTE A;  3PNR A;  4YYU A;  4YVA A;  3CBJ A;  3U8E A;  2GHU A;  2YJB A; 
#chains in the Genus database with same CATH topology
 3PRP A;  1KXR A;  2DZZ A;  2E00 A;  1CS8 A;  5CHT A;  3OF8 A;  1SP4 B;  2JQG R;  1MIR A;  1PBH A;  1AIM A;  1DF0 A;  4CDE B;  1O0E A;  2DZY A;  3USV A;  1X9Y A;  3QJ3 A;  1MEG A;  1QOL A;  5KO3 A;  2BU3 A;  1GLO A;  1HUC B;  3P5X A;  2DJG B;  1MEM A;  2WBF X;  1POP A;  4KLB A;  4MM3 B;  1TL9 A;  2DCC A;  3MOR A;  1NL6 A;  5JA7 A;  5JH3 A;  3V6C A;  2AYN A;  3F75 A;  3MJ5 A;  1YT7 A;  4XZX A;  2F7D A;  3RVV A;  2JRI A;  3PDF A;  1AU4 A;  3KSE A;  4N79 A;  4N8W A;  4RKX A;  4W5B A;  4BPV A;  4P6E A;  4HXD B;  2R9M A;  1KFX L;  2PRE A;  4BOQ A;  4R3D A;  1CB5 A;  3IEJ A;  4ZTB A;  3K8U A;  1KFU L;  4G54 A;  4X6J A;  3MHS A;  3C9E A;  2PAD A;  5F02 A;  5EZQ A;  1CVZ A;  1ATK A;  2GFO A;  4IUM A;  3B79 A;  3RNV A;  1EWM A;  2NQI A;  1UKF A;  3OIS A;  2HWK A;  2DC8 A;  3GCB A;  4BS6 A;  1U5I A;  4XUI A;  2E03 A;  2CB5 A;  1PPN A;  1K3B B;  1CJL A;  2BDL A;  4D8I A;  1DEU A;  1GEC E;  4QH6 A;  2UZJ A;  4REZ A;  2J7Q A;  4RY2 A;  2FUD A;  4FK5 A;  2AUX A;  3WXG A;  3HWN A;  3S3R A;  4X6H A;  2BDZ A;  4ZUX U;  2CIO A;  3TNX A;  1DKI A;  2R9O A;  3IMA A;  3HHA A;  3S3Q A;  4YYR A;  2R6N A;  4BQV A;  4WUR A;  3H89 A;  1STF E;  4MZS A;  2C0Y A;  1AEC A;  1YK8 A;  4AXL A;  2DC9 A;  1YAL A;  3BWK A;  3PT2 A;  4W4U A;  3PBH A;  4MSX A;  2R9N A;  1ICF A;  3W31 A;  3CH2 X;  4I04 A;  4RF0 A;  4I07 A;  1U9W A;  1NB3 A;  3O0U A;  2FT2 A;  1S4V A;  3KKU A;  1MS6 A;  2FTD A;  1U9V A;  4CDF B;  4QRG A;  1M6D A;  7PCK A;  5E6J A;  1AU2 A;  1F29 A;  3WXE A;  4OEM A;  2AU1 A;  5K16 A;  1AU3 A;  2FRA A;  2NQD B;  3WXF A;  3V6E A;  2DCD A;  1F2A A;  1NQC A;  2AS8 A;  3QSD A;  2B1M A;  3MTV A;  3N3G A;  2XU5 A;  3RVW A;  5A24 A;  1MDW A;  4XR7 A;  1EF7 A;  6PAD A;  3PHW A;  4FIP A;  1CPJ A;  3C0R A;  4OVZ B;  4BOP A;  2R9C A;  3H8C A;  1NB5 A;  3P5U A;  3ERV A;  3BPM A;  3M99 A;  4BSQ A;  4Q8G A;  3N3K A;  2NQG A;  2ATO A;  2YJ8 A;  1A6R A;  2PBH A;  1TLO A;  4Q8H A;  1MHW A;  4FJC A;  2PNS A;  1AYV A;  2AVW A;  1ME4 A;  3BBA A;  3BB7 A;  4MZO A;  1KHP A;  2JQF R;  5CVM A;  2DCB A;  2FO5 A;  3H7D A;  4QBB A;  1VSN A;  4CDC B;  2G8J A;  2OZ2 A;  1PAD A;  4BS5 A;  4GUA A;  3CH3 X;  4P6G A;  1PVJ A;  4RF1 A;  2E01 A;  1CV8 A;  3HHI A;  3KWZ A;  3CBK A;  3B21 A;  4OW0 A;  3TMP A;  4N4Z A;  3D6S A;  4M0W A;  3E1Z B;  1YVB A;  4WA6 A;  4BOS A;  2BTW B;  1XKG A;  2Z84 A;  3IFU A;  3ZUA A;  3OQC A;  4AXM A;  1PE6 A;  2AYO A;  5JZE A;  2P7U A;  2ACT A;  4P16 A;  3P5W A;  1ME3 A;  4QRV A;  2YJ2 A;  1YK7 A;  1F2C A;  2DJF B;  3IOQ A;  1NPZ A;  4DMY A;  4DMX A;  1PPP A;  3NHE A;  1YZB A;  1TU6 A;  3E9S A;  3AI8 A;  2DCA A;  4OEL A;  3LFY A;  4CZW A;  3KWB X;  1ITO A;  4QRX A;  3P5V A;  3PHX A;  4W5C A;  1SNK A;  3BOW A;  4CDD B;  3BC3 A;  4A5U A;  2AUZ A;  2FYE A;  1PXV A;  2DC7 A;  3K9M A;  3MHH A;  2G8E A;  1CQD A;  1QDQ A;  1AYW A;  1JQP A;  1CSB B;  5EGW A;  3BY4 A;  2YJ9 A;  4BOZ A;  1Q6K A;  4PP1 A;  4HWY A;  2OP3 A;  2XU1 A;  4YYV A;  2XU3 A;  4YYS A;  2Y5B A;  5CVO B;  1PPD A;  4YYW A;  1BGO A;  4PT5 A;  2P86 A;  1Y08 A;  2Y6E A;  3O1G A;  1BQI A;  9PAP A;  5EF4 A;  1U9X A;  1AYU A;  1PIP A;  2IPP B;  2XU4 A;  4BOU A;  1F2B A;  1KHQ A;  3ZNH A;  3KFQ A;  2VHS A;  1Y4H A;  3PW3 A;  2HD5 A;  3H8B A;  1GCB A;  4PAD A;  2OUL A;  3HD3 A;  4PP2 E;  2F1G A;  1EWO A;  2R9F A;  2HXZ A;  2FRQ A;  2FQ9 A;  1BY8 A;  5CHV A;  4OVZ A;  1EWP A;  2JTC A;  3MP2 A;  4YYQ A;  3H6S A;  3I06 A;  4K7C A;  4PI3 A;  2J7Q C;  3DF0 A;  2AGA A;  1IWD A;  3F5V A;  1ZCM A;  3KX1 A;  2G7Y A;  2NQA A;  3LXS A;  3N4C A;  2DC6 A;  3PHU A;  5CVN B;  2FE8 A;  1EWL A;  3BPF A;  1NLJ A;  2VHF A;  3IV2 A;  2ARY A;  8PCH A;  4MI7 A;  1U9Q X;  1ZIV A;  2H7J A;  3IHP A;  1PPO A;  3OVX A;  3PSE A;  4YV8 A;  2DOS A;  2G6D A;  1VJV A;  5J94 A;  2O6X A;  1THE A;  2IBI A;  3OF9 A;  4I05 A;  1PCI A;  3O65 A;  1QMY A;  1QXP A;  3OVZ A;  2P0R A;  3K24 A;  4IP3 A;  1FH0 A;  3QT4 A;  5FPW A;  2AIM A;  3I3T A;  2BTW A;  3RVX A;  4D8E A;  4RNA A;  2HH5 A;  2HHN A;  1GMY A;  2B1N A;  2E02 A;  3W30 A;  2YJC A;  1AU0 A;  5PAD A;  1BP4 A;  5EZS A;  3MTN A;  3BCN A;  4X6I A;  3IUT A;  3KW9 A;  3PRM A;  4D8B A;  1CTE A;  3PNR A;  4YYU A;  4YVA A;  3CBJ A;  3U8E A;  2GHU A;  3TRK A;  2YJB A; 
#chains in the Genus database with same CATH homology
 1KXR A;  2DZZ A;  2E00 A;  1CS8 A;  5CHT A;  3OF8 A;  1SP4 B;  2JQG R;  1MIR A;  4NV8 A;  1PBH A;  1AIM A;  1DF0 A;  4CDE B;  1O0E A;  2DZY A;  3USV A;  1X9Y A;  3QJ3 A;  1MEG A;  1QOL A;  4BGF A;  1GLO A;  1HUC B;  3P5X A;  2DJG B;  1MEM A;  2WBF X;  1POP A;  4KLB A;  1TL9 A;  2DCC A;  3MOR A;  2BSZ A;  1NL6 A;  5JA7 A;  5JH3 A;  3V6C A;  2AYN A;  3F75 A;  1YT7 A;  2F7D A;  3RVV A;  3PDF A;  1AU4 A;  3KSE A;  4N79 A;  4N8W A;  4W5B A;  4BPV A;  4P6E A;  2R9M A;  1KFX L;  2PRE A;  1CB5 A;  3IEJ A;  3K8U A;  1KFU L;  4G54 A;  4X6J A;  3MHS A;  3C9E A;  2PAD A;  5F02 A;  1CVZ A;  1ATK A;  2GFO A;  3B79 A;  1EWM A;  2NQI A;  3OIS A;  2DC8 A;  3GCB A;  4BS6 A;  1U5I A;  4XUI A;  2E03 A;  2CB5 A;  1PPN A;  1K3B B;  1CJL A;  2BDL A;  1DEU A;  1GEC E;  4QH6 A;  4RY2 A;  2FUD A;  4FK5 A;  2AUX A;  3WXG A;  3HWN A;  3S3R A;  4X6H A;  2BDZ A;  4ZUX U;  2CIO A;  3TNX A;  2R9O A;  3IMA A;  3HHA A;  3S3Q A;  4YYR A;  2R6N A;  4BQV A;  3H89 A;  1STF E;  4MZS A;  2C0Y A;  1AEC A;  1YK8 A;  4AXL A;  2DC9 A;  1YAL A;  3BWK A;  4W4U A;  3PBH A;  4MSX A;  2R9N A;  1ICF A;  3CH2 X;  4I04 A;  4I07 A;  1U9W A;  1NB3 A;  3O0U A;  2FT2 A;  1S4V A;  3KKU A;  1MS6 A;  2FTD A;  1U9V A;  4CDF B;  4QRG A;  1M6D A;  7PCK A;  1AU2 A;  1F29 A;  3WXE A;  4OEM A;  2AU1 A;  5K16 A;  1AU3 A;  2FRA A;  2NQD B;  3WXF A;  3V6E A;  2DCD A;  1F2A A;  1NQC A;  2AS8 A;  3QSD A;  2B1M A;  3N3G A;  2XU5 A;  3RVW A;  5A24 A;  1MDW A;  4XR7 A;  1EF7 A;  6PAD A;  4FIP A;  1CPJ A;  2R9C A;  3H8C A;  1NB5 A;  3ERV A;  3P5U A;  3BPM A;  3M99 A;  4BSQ A;  4Q8G A;  3N3K A;  2NQG A;  2ATO A;  2YJ8 A;  1A6R A;  2PBH A;  1TLO A;  4Q8H A;  1MHW A;  4FJC A;  2PNS A;  1AYV A;  2AVW A;  1ME4 A;  4MZO A;  1KHP A;  1GX3 A;  2JQF R;  5CVM A;  2DCB A;  2FO5 A;  3H7D A;  4QBB A;  1VSN A;  4CDC B;  2G8J A;  2OZ2 A;  1PAD A;  4BS5 A;  3CH3 X;  4B55 A;  4P6G A;  2E01 A;  1CV8 A;  3HHI A;  3KWZ A;  3CBK A;  4GUZ A;  4N4Z A;  3D6S A;  3E1Z B;  1YVB A;  4WA6 A;  1XKG A;  3ZUA A;  4AXM A;  1PE6 A;  2AYO A;  2P7U A;  2ACT A;  3P5W A;  1ME3 A;  4QRV A;  4NV7 A;  2YJ2 A;  1YK7 A;  1F2C A;  2DJF B;  3IOQ A;  1NPZ A;  4DMY A;  4DMX A;  1PPP A;  3NHE A;  3D9W A;  1W6F A;  1TU6 A;  3AI8 A;  2DCA A;  4OEL A;  3LFY A;  4CZW A;  3KWB X;  1ITO A;  4QRX A;  3P5V A;  4W5C A;  1SNK A;  3BOW A;  4CDD B;  3BC3 A;  2AUZ A;  2FYE A;  1PXV A;  2DC7 A;  3K9M A;  3MHH A;  2G8E A;  1CQD A;  1QDQ A;  1AYW A;  1JQP A;  1CSB B;  5EGW A;  1W5R A;  2YJ9 A;  1Q6K A;  4PP1 A;  4HWY A;  2OP3 A;  2XU1 A;  4YYV A;  2XU3 A;  4YYS A;  2Y5B A;  5CVO B;  1PPD A;  4YYW A;  1BGO A;  2P86 A;  1Y08 A;  2Y6E A;  3O1G A;  1BQI A;  9PAP A;  5EF4 A;  1U9X A;  1AYU A;  1PIP A;  2VFC A;  2IPP B;  2XU4 A;  1F2B A;  1KHQ A;  1W4T A;  3KFQ A;  2VHS A;  1Y4H A;  3PW3 A;  2HD5 A;  3H8B A;  1GCB A;  4PAD A;  2OUL A;  3HD3 A;  4PP2 E;  2F1G A;  1EWO A;  2R9F A;  2HXZ A;  2FRQ A;  2FQ9 A;  1BY8 A;  5CHV A;  1EWP A;  4YYQ A;  3H6S A;  3I06 A;  4K7C A;  4PI3 A;  3DF0 A;  1IWD A;  3F5V A;  1ZCM A;  3KX1 A;  2G7Y A;  2NQA A;  3LXS A;  3N4C A;  2DC6 A;  5CVN B;  1EWL A;  3BPF A;  1NLJ A;  2VHF A;  3IV2 A;  2ARY A;  8PCH A;  1U9Q X;  1ZIV A;  2H7J A;  3IHP A;  1PPO A;  3OVX A;  4YV8 A;  2G6D A;  1VJV A;  5J94 A;  2O6X A;  1THE A;  2IBI A;  3OF9 A;  4I05 A;  1PCI A;  3LTW A;  1QMY A;  1QXP A;  3OVZ A;  2P0R A;  1E2T A;  3K24 A;  1FH0 A;  3QT4 A;  5FPW A;  2AIM A;  3I3T A;  4C5P A;  3RVX A;  2HH5 A;  2HHN A;  1GMY A;  2B1N A;  2E02 A;  2YJC A;  1AU0 A;  5PAD A;  1BP4 A;  3MTN A;  3BCN A;  4X6I A;  3IUT A;  3KW9 A;  2VFB A;  1CTE A;  3PNR A;  4YYU A;  4YVA A;  3CBJ A;  3U8E A;  2GHU A;  2YJB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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