2FYEA

Mutant human cathepsin s with irreversible inhibitor cra-14013
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
217
structure length
217
Chain Sequence
LPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTKKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSAYRAATCRKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEKGYIRMARNKGNHCGIASFPSYPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutant Human Cathepsin S with irreversible inhibitor CRA-14013
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords cathepsin S preproprotein
total genus 66
structure length 217
sequence length 217
ec nomenclature ec 3.4.22.27: Cathepsin S.
pdb deposition date 2006-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2fyeA00
3BOWA 3H8BA 3HHIA 3MTNA 3H6SA 3B79A 2CIOA 1EF7A 1GCBA 1A6RA 2YJBA 1PPDA 3MHSA 1YVBA 2E01A 3I06A 3LXSA 4CDCB 1ZCMA 2AIMA 4N8WA 2ARYA 2DZZA 4X6JA 2IBIA 1AECA 1FH0A 3IUTA 2DCCA 1QXPA 2AUXA 4CDDB 2JQGR 2HH5A 4RY2A 1YALA 2WBFX 1ICFA 4Q8HA 1YK7A 4P6GA 2DC6A 4DMYA 2XU1A 4I04A 1QMYA 3P5VA 4PI3A 1HUCB 3BCNA 2PADA 3O1GA 8PCHA 2YJ2A 3OF9A 2FUDA 1CSBB 1U9WA 5PADA 3QT4A 1YK8A 1CQDA 3USVA 2FO5A 1NB3A 2C0YA 1ME3A 2ATOA 2G7YA 5FPWA 4WA6A 3RVVA 3KFQA 2P7UA 4QRGA 3F5VA 2XU4A 2E03A 3E1ZB 1BGOA 4AXLA 4K7CA 4W5BA 3OF8A 5CHVA 4YV8A 3H8CA 1MEMA 1NPZA 1KHPA 4OEMA 5CVMA 2FRAA 1VJVA 4W4UA 4W5CA 2P86A 5CHTA 2R9FA 1PADA 1YT7A 1AYVA 5K16A 2R9CA 9PAPA 3KKUA 2BDLA 4MZOA 2FYEA 2NQIA 1PBHA 4KLBA 2F1GA 4QH6A 4YYWA 1NQCA 3H7DA 1PE6A 4CDFB 4X6IA 2AU1A 1PPPA 1EWOA 2DJGB 3PW3A 4HWYA 2PBHA 1U9VA 2R9MA 4YYSA 1NL6A 3O0UA 3PDFA 2HXZA 3S3QA 4PP1A 1MDWA 3F75A 3CBKA 4MZSA 1CV8A 3P5UA 2DCDA 2PREA 1ZIVA 2PNSA 4QBBA 1TL9A 2FTDA 1O0EA 2OULA 1K3BB 1Q6KA 2FT2A 2DCBA 4CDEB 4BPVA 1THEA 4I07A 3N3GA 1S4VA 1NLJA 1TU6A 4DMXA 2NQAA 3RVXA 3HHAA 1PIPA 1GECE 4BQVA 1PPNA 2B1NA 1SP4B 2DC7A 2JQFR 2FRQA 1X9YA 5EGWA 1MIRA 4FIPA 4OELA 5JH3A 3OVXA 2R9OA 4XR7A 3ZUAA 3P5WA 4MSXA 3IHPA 1CS8A 6PADA 4YYQA 4BS6A 4N4ZA 4PP2E 4XUIA 5A24A 3AI8A 1KXRA 3I3TA 2B1MA 2F7DA 3PBHA 1DF0A 1EWLA 4PADA 1MS6A 1AIMA 3K24A 2G8EA 2DC8A 4YYRA 1KFXL 2IPPB 4X6HA 1ME4A 3QJ3A 2Y6EA 1JQPA 3BC3A 2R6NA 3WXEA 4QRXA 3V6EA 2GHUA 1KHQA 1GMYA 3BPMA 3KSEA 5JA7A 2H7JA 2G6DA 4QRVA 4YVAA 3M99A 4P6EA 2FQ9A 1PXVA 1F2CA 1U9QX 5EF4A 1PCIA 4BSQA 2VHSA 2G8JA 4FK5A 3MHHA 1AYWA 5F02A 2XU3A 2DJFB 4Q8GA 4ZUXU 1BQIA 4FJCA 3GCBA 1U5IA 2OP3A 5CVOB 1IWDA 2VHFA 3S3RA 1AU2A 2P0RA 1BP4A 1M6DA 1DEUA 2AYOA 2HD5A 3H89A 1CPJA 2AVWA 3HD3A 2DZYA 3IOQA 3TNXA 1ITOA 1CVZA 2BDZA 3HWNA 3CH3X 1SNKA 1VSNA 1AYUA 3CH2X 1Y08A 3U8EA 5J94A 3P5XA 1AU0A 3V6CA 5CVNB 1EWMA 2E00A 3PNRA 4YYVA 1F2AA 2NQDB 1PPOA 2O6XA 2YJ8A 3IV2A 1AU4A 2AS8A 4AXMA 1GLOA 3K8UA 3N3KA 4G54A 7PCKA 2GFOA 1QDQA 1ATKA 2HHNA 1XKGA 1F2BA 2AYNA 2YJCA 1BY8A 2YJ9A 3KWZA 4CZWA 3NHEA 3KW9A 3OVZA 1Y4HA 4YYUA 1F29A 3N4CA 1MEGA 3D6SA 3KWBX 2Y5BA 3BPFA 1CB5A 4N79A 3DF0A 1CJLA 1U9XA 2DCAA 3WXFA 4I05A 1STFE 4BS5A 2DC9A 3CBJA 2XU5A 3MORA 2R9NA 3ERVA 2NQGA 1EWPA 3IMAA 1AU3A 1MHWA 1QOLA 1NB5A 1TLOA 3BWKA 1KFUL 2OZ2A 3OISA 3WXGA 3K9MA 2ACTA 1CTEA 2CB5A 3IEJA 3KX1A 3RVWA 3C9EA 2E02A 3QSDA 3LFYA 1POPA 2AUZA
chains in the Genus database with same CATH superfamily
3BOWA 2BU3A 4IP3A 4M0WA 3H8BA 3HHIA 3MTNA 3H6SA 3B79A 2BTWA 2CIOA 1EF7A 2FE8A 1GCBA 1A6RA 2YJBA 1PPDA 3MHSA 1YVBA 2E01A 3I06A 3LXSA 4CDCB 1ZCMA 2AIMA 4XZXA 4N8WA 2ARYA 2DZZA 4BOSA 4X6JA 2IBIA 1AECA 1FH0A 3IUTA 2DCCA 1QXPA 2AUXA 2J7QC 4MM3B 3BY4A 4CDDB 2JQGR 2HH5A 5EZQA 4RY2A 1YALA 2WBFX 1ICFA 4Q8HA 1YK7A 4P6GA 2DC6A 1PVJA 4DMYA 2XU1A 4I04A 1QMYA 3P5VA 4PI3A 4PT5A 1HUCB 3BCNA 2PADA 3O1GA 8PCHA 2YJ2A 3OF9A 2FUDA 1CSBB 1U9WA 5PADA 3QT4A 3OQCA 3RNVA 1YK8A 1CQDA 3USVA 3C0RA 2FO5A 1NB3A 2C0YA 1ME3A 4D8BA 2ATOA 2G7YA 5FPWA 4WA6A 3RVVA 3KFQA 2P7UA 2Z84A 1YZBA 4QRGA 3F5VA 2XU4A 2E03A 3E1ZB 1BGOA 2JTCA 4AXLA 4OVZB 4K7CA 4WURA 4W5BA 3OF8A 5CHVA 4YV8A 3H8CA 1MEMA 1NPZA 4D8IA 1KHPA 4OEMA 2HWKA 5CVMA 4A5UA 2FRAA 3E9SA 3W31A 1VJVA 4W4UA 4W5CA 2P86A 5CHTA 2R9FA 1PADA 1YT7A 2DOSA 4RKXA 1AYVA 5K16A 2R9CA 9PAPA 3KKUA 2BDLA 4MZOA 2FYEA 2NQIA 1PBHA 4KLBA 2F1GA 3PHWA 4QH6A 4YYWA 1NQCA 3H7DA 1PE6A 4CDFB 4ZTBA 4X6IA 2AU1A 1PPPA 1EWOA 2DJGB 3PW3A 4HWYA 2PBHA 1U9VA 2R9MA 4YYSA 5EZSA 1NL6A 3O0UA 4BOQA 3PDFA 2HXZA 3S3QA 4PP1A 1MDWA 3F75A 3CBKA 4MZSA 1CV8A 3P5UA 2DCDA 2PREA 1ZIVA 2PNSA 4QBBA 3IFUA 1TL9A 2FTDA 1O0EA 2OULA 1K3BB 1Q6KA 2FT2A 2DCBA 4CDEB 4BPVA 1THEA 3BB7A 4I07A 3N3GA 1S4VA 1NLJA 3PRMA 3MJ5A 1TU6A 4DMXA 2NQAA 3RVXA 3HHAA 1PIPA 1GECE 4BQVA 2AGAA 1UKFA 1PPNA 2B1NA 1SP4B 2DC7A 2JQFR 2FRQA 1X9YA 5EGWA 1MIRA 4BOUA 4FIPA 4OELA 5JH3A 5KO3A 3OVXA 2R9OA 4XR7A 4RF0A 4OW0A 3ZUAA 3P5WA 4MSXA 3IHPA 1CS8A 6PADA 4YYQA 4BS6A 4N4ZA 4PP2E 4XUIA 5A24A 3AI8A 1KXRA 3I3TA 4MI7A 2B1MA 2F7DA 2JRIA 3PBHA 1DKIA 1DF0A 4BOZA 3PHXA 1EWLA 2BTWB 4PADA 1MS6A 1AIMA 3K24A 2G8EA 2DC8A 4RNAA 4YYRA 1KFXL 2IPPB 5E6JA 4X6HA 1ME4A 3QJ3A 2Y6EA 1JQPA 3BC3A 3MP2A 2R6NA 4GUAA 3WXEA 3PHUA 4QRXA 3V6EA 2GHUA 1KHQA 1GMYA 3BPMA 3KSEA 5JA7A 2H7JA 2G6DA 4QRVA 3PSEA 4YVAA 3M99A 4P6EA 4HXDB 2FQ9A 4OVZA 1PXVA 3TRKA 1F2CA 1U9QX 5EF4A 1PCIA 4BSQA 2VHSA 2G8JA 4BOPA 4FK5A 3MHHA 1AYWA 5F02A 3BBAA 2XU3A 2DJFB 4Q8GA 4ZUXU 1BQIA 4FJCA 3GCBA 1U5IA 2OP3A 5CVOB 1IWDA 2VHFA 3S3RA 1AU2A 2P0RA 1BP4A 1M6DA 1DEUA 2AYOA 3MTVA 4P16A 2HD5A 3H89A 1CPJA 2AVWA 3HD3A 2DZYA 3IOQA 3TNXA 1ITOA 1CVZA 2BDZA 3HWNA 3CH3X 1SNKA 1VSNA 1AYUA 3CH2X 1Y08A 3PRPA 3U8EA 5J94A 3P5XA 1AU0A 3V6CA 5CVNB 1EWMA 2E00A 3PNRA 4YYVA 1F2AA 5JZEA 2NQDB 1PPOA 2O6XA 2YJ8A 3IV2A 1AU4A 2AS8A 4AXMA 1GLOA 3B21A 3K8UA 3N3KA 3TMPA 4G54A 7PCKA 2GFOA 1QDQA 4RF1A 1ATKA 2HHNA 1XKGA 1F2BA 2AYNA 2YJCA 1BY8A 2YJ9A 3KWZA 4CZWA 3NHEA 3KW9A 3OVZA 1Y4HA 4YYUA 1F29A 4D8EA 3N4CA 1MEGA 3D6SA 3KWBX 2Y5BA 3BPFA 1CB5A 4N79A 3PT2A 3DF0A 1CJLA 1U9XA 2DCAA 3ZNHA 3WXFA 4I05A 1STFE 4BS5A 2DC9A 3CBJA 2J7QA 3O65A 2XU5A 2UZJA 3MORA 2R9NA 3ERVA 2NQGA 4REZA 1EWPA 3IMAA 1AU3A 4R3DA 1MHWA 1QOLA 1NB5A 1TLOA 3BWKA 1KFUL 2OZ2A 3OISA 3WXGA 3K9MA 2ACTA 1CTEA 2CB5A 3IEJA 3KX1A 3RVWA 3C9EA 2E02A 3QSDA 3LFYA 1POPA 3W30A 4IUMA 2AUZA
chains in the Genus database with same CATH topology
3BOWA 3H8BA 3HHIA 3MTNA 3H6SA 3B79A 2CIOA 1EF7A 4C5PA 1GCBA 1A6RA 2YJBA 1PPDA 3MHSA 1YVBA 2E01A 3I06A 3LXSA 4CDCB 1ZCMA 2AIMA 4N8WA 2ARYA 2DZZA 4X6JA 2IBIA 1AECA 1FH0A 3IUTA 2DCCA 1QXPA 2AUXA 4CDDB 2JQGR 2HH5A 4RY2A 1YALA 2WBFX 1ICFA 4Q8HA 1YK7A 4P6GA 2DC6A 4DMYA 2XU1A 4I04A 1QMYA 3P5VA 4PI3A 1HUCB 3BCNA 2PADA 3O1GA 8PCHA 1GX3A 2YJ2A 3OF9A 2FUDA 1CSBB 1U9WA 5PADA 3QT4A 1YK8A 1CQDA 3USVA 2FO5A 1NB3A 2C0YA 1ME3A 2ATOA 2G7YA 5FPWA 4WA6A 3RVVA 3KFQA 2P7UA 4QRGA 3F5VA 2XU4A 2E03A 3E1ZB 1BGOA 4AXLA 4K7CA 4W5BA 1W4TA 3OF8A 5CHVA 4YV8A 3H8CA 1MEMA 1NPZA 1E2TA 1KHPA 4OEMA 5CVMA 2FRAA 4BGFA 1VJVA 4W4UA 4W5CA 2P86A 5CHTA 2R9FA 1PADA 1YT7A 2BSZA 1AYVA 5K16A 2R9CA 9PAPA 3KKUA 2BDLA 4MZOA 2FYEA 2NQIA 1PBHA 4KLBA 2F1GA 4QH6A 4YYWA 1NQCA 3H7DA 1PE6A 4CDFB 4X6IA 2AU1A 1PPPA 1EWOA 2DJGB 3PW3A 4HWYA 2PBHA 1U9VA 2R9MA 4YYSA 1NL6A 3O0UA 3PDFA 2HXZA 1W6FA 3S3QA 4PP1A 1MDWA 3F75A 3CBKA 4MZSA 1CV8A 3P5UA 2DCDA 2PREA 1ZIVA 2PNSA 4QBBA 1TL9A 2FTDA 1O0EA 2OULA 1K3BB 1Q6KA 2FT2A 2DCBA 4CDEB 4GUZA 4BPVA 2VFCA 1THEA 4I07A 3N3GA 1S4VA 1NLJA 1TU6A 4DMXA 2NQAA 3RVXA 3HHAA 1PIPA 1GECE 4BQVA 1PPNA 2B1NA 1SP4B 2DC7A 2JQFR 2FRQA 1X9YA 5EGWA 1MIRA 2VFBA 4FIPA 4OELA 5JH3A 3OVXA 2R9OA 4XR7A 3ZUAA 3P5WA 4MSXA 3IHPA 1CS8A 6PADA 4YYQA 4BS6A 4N4ZA 4PP2E 4XUIA 5A24A 3AI8A 1KXRA 3I3TA 2B1MA 2F7DA 3PBHA 1DF0A 1EWLA 4PADA 1MS6A 1AIMA 3K24A 2G8EA 2DC8A 3D9WA 4YYRA 1KFXL 2IPPB 3LTWA 1ME4A 3QJ3A 4X6HA 2Y6EA 1JQPA 3BC3A 1W5RA 2R6NA 3WXEA 4QRXA 3V6EA 2GHUA 1KHQA 1GMYA 3BPMA 3KSEA 5JA7A 2H7JA 2G6DA 4QRVA 4YVAA 3M99A 4P6EA 2FQ9A 1PXVA 1F2CA 1U9QX 5EF4A 1PCIA 4BSQA 2VHSA 2G8JA 4FK5A 3MHHA 1AYWA 5F02A 2XU3A 2DJFB 4Q8GA 4ZUXU 1BQIA 4FJCA 3GCBA 1U5IA 2OP3A 5CVOB 1IWDA 2VHFA 3S3RA 1AU2A 2P0RA 1BP4A 1M6DA 1DEUA 2AYOA 2HD5A 3H89A 1CPJA 2AVWA 3HD3A 2DZYA 3IOQA 3TNXA 1ITOA 1CVZA 2BDZA 3HWNA 3CH3X 1SNKA 1VSNA 1AYUA 3CH2X 1Y08A 3U8EA 5J94A 3P5XA 1AU0A 3V6CA 5CVNB 4NV8A 1EWMA 2E00A 3PNRA 4YYVA 1F2AA 2NQDB 1PPOA 2O6XA 2YJ8A 3IV2A 1AU4A 2AS8A 4AXMA 1GLOA 3K8UA 3N3KA 4G54A 7PCKA 2GFOA 1QDQA 1ATKA 4B55A 2HHNA 1XKGA 1F2BA 2AYNA 2YJCA 1BY8A 2YJ9A 3KWZA 4CZWA 3NHEA 3KW9A 3OVZA 1Y4HA 4YYUA 1F29A 3N4CA 1MEGA 3D6SA 3KWBX 2Y5BA 3BPFA 1CB5A 4N79A 3DF0A 1CJLA 1U9XA 2DCAA 3WXFA 4NV7A 4I05A 1STFE 4BS5A 2DC9A 3CBJA 2XU5A 3MORA 2R9NA 3ERVA 2NQGA 1EWPA 3IMAA 1AU3A 1MHWA 1QOLA 1NB5A 1TLOA 3BWKA 1KFUL 2OZ2A 3OISA 3WXGA 3K9MA 2ACTA 1CTEA 2CB5A 3IEJA 3KX1A 3RVWA 3C9EA 3QSDA 2E02A 3LFYA 1POPA 2AUZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BOW A;  3H8B A;  3HHI A;  3MTN A;  3H6S A;  3B79 A;  2CIO A;  1EF7 A;  1GCB A;  1A6R A;  2YJB A;  1PPD A;  3MHS A;  1YVB A;  2E01 A;  3I06 A;  3LXS A;  4CDC B;  1ZCM A;  2AIM A;  4N8W A;  2ARY A;  2DZZ A;  4X6J A;  2IBI A;  1AEC A;  1FH0 A;  3IUT A;  2DCC A;  1QXP A;  2AUX A;  4CDD B;  2JQG R;  2HH5 A;  4RY2 A;  1YAL A;  2WBF X;  1ICF A;  4Q8H A;  1YK7 A;  4P6G A;  2DC6 A;  4DMY A;  2XU1 A;  4I04 A;  1QMY A;  3P5V A;  4PI3 A;  1HUC B;  3BCN A;  2PAD A;  3O1G A;  8PCH A;  2YJ2 A;  3OF9 A;  2FUD A;  1CSB B;  1U9W A;  5PAD A;  3QT4 A;  1YK8 A;  1CQD A;  3USV A;  2FO5 A;  1NB3 A;  2C0Y A;  1ME3 A;  2ATO A;  2G7Y A;  5FPW A;  4WA6 A;  3RVV A;  3KFQ A;  2P7U A;  4QRG A;  3F5V A;  2XU4 A;  2E03 A;  3E1Z B;  1BGO A;  4AXL A;  4K7C A;  4W5B A;  3OF8 A;  5CHV A;  4YV8 A;  3H8C A;  1MEM A;  1NPZ A;  1KHP A;  4OEM A;  5CVM A;  2FRA A;  1VJV A;  4W4U A;  4W5C A;  2P86 A;  5CHT A;  2R9F A;  1PAD A;  1YT7 A;  1AYV A;  5K16 A;  2R9C A;  9PAP A;  3KKU A;  2BDL A;  4MZO A;  2FYE A;  2NQI A;  1PBH A;  4KLB A;  2F1G A;  4QH6 A;  4YYW A;  1NQC A;  3H7D A;  1PE6 A;  4CDF B;  4X6I A;  2AU1 A;  1PPP A;  1EWO A;  2DJG B;  3PW3 A;  4HWY A;  2PBH A;  1U9V A;  2R9M A;  4YYS A;  1NL6 A;  3O0U A;  3PDF A;  2HXZ A;  3S3Q A;  4PP1 A;  1MDW A;  3F75 A;  3CBK A;  4MZS A;  1CV8 A;  3P5U A;  2DCD A;  2PRE A;  1ZIV A;  2PNS A;  4QBB A;  1TL9 A;  2FTD A;  1O0E A;  2OUL A;  1K3B B;  1Q6K A;  2FT2 A;  2DCB A;  4CDE B;  4BPV A;  1THE A;  4I07 A;  3N3G A;  1S4V A;  1NLJ A;  1TU6 A;  4DMX A;  2NQA A;  3RVX A;  3HHA A;  1PIP A;  1GEC E;  4BQV A;  1PPN A;  2B1N A;  1SP4 B;  2DC7 A;  2JQF R;  2FRQ A;  1X9Y A;  5EGW A;  1MIR A;  4FIP A;  4OEL A;  5JH3 A;  3OVX A;  2R9O A;  4XR7 A;  3ZUA A;  3P5W A;  4MSX A;  3IHP A;  1CS8 A;  6PAD A;  4YYQ A;  4BS6 A;  4N4Z A;  4PP2 E;  4XUI A;  5A24 A;  3AI8 A;  1KXR A;  3I3T A;  2B1M A;  2F7D A;  3PBH A;  1DF0 A;  1EWL A;  4PAD A;  1MS6 A;  1AIM A;  3K24 A;  2G8E A;  2DC8 A;  4YYR A;  1KFX L;  2IPP B;  4X6H A;  1ME4 A;  3QJ3 A;  2Y6E A;  1JQP A;  3BC3 A;  2R6N A;  3WXE A;  4QRX A;  3V6E A;  2GHU A;  1KHQ A;  1GMY A;  3BPM A;  3KSE A;  5JA7 A;  2H7J A;  2G6D A;  4QRV A;  4YVA A;  3M99 A;  4P6E A;  2FQ9 A;  1PXV A;  1F2C A;  1U9Q X;  5EF4 A;  1PCI A;  4BSQ A;  2VHS A;  2G8J A;  4FK5 A;  3MHH A;  1AYW A;  5F02 A;  2XU3 A;  2DJF B;  4Q8G A;  4ZUX U;  1BQI A;  4FJC A;  3GCB A;  1U5I A;  2OP3 A;  5CVO B;  1IWD A;  2VHF A;  3S3R A;  1AU2 A;  2P0R A;  1BP4 A;  1M6D A;  1DEU A;  2AYO A;  2HD5 A;  3H89 A;  1CPJ A;  2AVW A;  3HD3 A;  2DZY A;  3IOQ A;  3TNX A;  1ITO A;  1CVZ A;  2BDZ A;  3HWN A;  3CH3 X;  1SNK A;  1VSN A;  1AYU A;  3CH2 X;  1Y08 A;  3U8E A;  5J94 A;  3P5X A;  1AU0 A;  3V6C A;  5CVN B;  1EWM A;  2E00 A;  3PNR A;  4YYV A;  1F2A A;  2NQD B;  1PPO A;  2O6X A;  2YJ8 A;  3IV2 A;  1AU4 A;  2AS8 A;  4AXM A;  1GLO A;  3K8U A;  3N3K A;  4G54 A;  7PCK A;  2GFO A;  1QDQ A;  1ATK A;  2HHN A;  1XKG A;  1F2B A;  2AYN A;  2YJC A;  1BY8 A;  2YJ9 A;  3KWZ A;  4CZW A;  3NHE A;  3KW9 A;  3OVZ A;  1Y4H A;  4YYU A;  1F29 A;  3N4C A;  1MEG A;  3D6S A;  3KWB X;  2Y5B A;  3BPF A;  1CB5 A;  4N79 A;  3DF0 A;  1CJL A;  1U9X A;  2DCA A;  3WXF A;  4I05 A;  1STF E;  4BS5 A;  2DC9 A;  3CBJ A;  2XU5 A;  3MOR A;  2R9N A;  3ERV A;  2NQG A;  1EWP A;  3IMA A;  1AU3 A;  1MHW A;  1QOL A;  1NB5 A;  1TLO A;  3BWK A;  1KFU L;  2OZ2 A;  3OIS A;  3WXG A;  3K9M A;  2ACT A;  1CTE A;  2CB5 A;  3IEJ A;  3KX1 A;  3RVW A;  3C9E A;  2E02 A;  3QSD A;  3LFY A;  1POP A;  2AUZ A; 
#chains in the Genus database with same CATH topology
 3BOW A;  2BU3 A;  4IP3 A;  4M0W A;  3H8B A;  3HHI A;  3MTN A;  3H6S A;  3B79 A;  2BTW A;  2CIO A;  1EF7 A;  2FE8 A;  1GCB A;  1A6R A;  2YJB A;  1PPD A;  3MHS A;  1YVB A;  2E01 A;  3I06 A;  3LXS A;  4CDC B;  1ZCM A;  2AIM A;  4XZX A;  4N8W A;  2ARY A;  2DZZ A;  4BOS A;  4X6J A;  2IBI A;  1AEC A;  1FH0 A;  3IUT A;  2DCC A;  1QXP A;  2AUX A;  2J7Q C;  4MM3 B;  3BY4 A;  4CDD B;  2JQG R;  2HH5 A;  5EZQ A;  4RY2 A;  1YAL A;  2WBF X;  1ICF A;  4Q8H A;  1YK7 A;  4P6G A;  2DC6 A;  1PVJ A;  4DMY A;  2XU1 A;  4I04 A;  1QMY A;  3P5V A;  4PI3 A;  4PT5 A;  1HUC B;  3BCN A;  2PAD A;  3O1G A;  8PCH A;  2YJ2 A;  3OF9 A;  2FUD A;  1CSB B;  1U9W A;  5PAD A;  3QT4 A;  3OQC A;  3RNV A;  1YK8 A;  1CQD A;  3USV A;  3C0R A;  2FO5 A;  1NB3 A;  2C0Y A;  1ME3 A;  4D8B A;  2ATO A;  2G7Y A;  5FPW A;  4WA6 A;  3RVV A;  3KFQ A;  2P7U A;  2Z84 A;  1YZB A;  4QRG A;  3F5V A;  2XU4 A;  2E03 A;  3E1Z B;  1BGO A;  2JTC A;  4AXL A;  4OVZ B;  4K7C A;  4WUR A;  4W5B A;  3OF8 A;  5CHV A;  4YV8 A;  3H8C A;  1MEM A;  1NPZ A;  4D8I A;  1KHP A;  4OEM A;  2HWK A;  5CVM A;  4A5U A;  2FRA A;  3E9S A;  3W31 A;  1VJV A;  4W4U A;  4W5C A;  2P86 A;  5CHT A;  2R9F A;  1PAD A;  1YT7 A;  2DOS A;  4RKX A;  1AYV A;  5K16 A;  2R9C A;  9PAP A;  3KKU A;  2BDL A;  4MZO A;  2FYE A;  2NQI A;  1PBH A;  4KLB A;  2F1G A;  3PHW A;  4QH6 A;  4YYW A;  1NQC A;  3H7D A;  1PE6 A;  4CDF B;  4ZTB A;  4X6I A;  2AU1 A;  1PPP A;  1EWO A;  2DJG B;  3PW3 A;  4HWY A;  2PBH A;  1U9V A;  2R9M A;  4YYS A;  5EZS A;  1NL6 A;  3O0U A;  4BOQ A;  3PDF A;  2HXZ A;  3S3Q A;  4PP1 A;  1MDW A;  3F75 A;  3CBK A;  4MZS A;  1CV8 A;  3P5U A;  2DCD A;  2PRE A;  1ZIV A;  2PNS A;  4QBB A;  3IFU A;  1TL9 A;  2FTD A;  1O0E A;  2OUL A;  1K3B B;  1Q6K A;  2FT2 A;  2DCB A;  4CDE B;  4BPV A;  1THE A;  3BB7 A;  4I07 A;  3N3G A;  1S4V A;  1NLJ A;  3PRM A;  3MJ5 A;  1TU6 A;  4DMX A;  2NQA A;  3RVX A;  3HHA A;  1PIP A;  1GEC E;  4BQV A;  2AGA A;  1UKF A;  1PPN A;  2B1N A;  1SP4 B;  2DC7 A;  2JQF R;  2FRQ A;  1X9Y A;  5EGW A;  1MIR A;  4BOU A;  4FIP A;  4OEL A;  5JH3 A;  5KO3 A;  3OVX A;  2R9O A;  4XR7 A;  4RF0 A;  4OW0 A;  3ZUA A;  3P5W A;  4MSX A;  3IHP A;  1CS8 A;  6PAD A;  4YYQ A;  4BS6 A;  4N4Z A;  4PP2 E;  4XUI A;  5A24 A;  3AI8 A;  1KXR A;  3I3T A;  4MI7 A;  2B1M A;  2F7D A;  2JRI A;  3PBH A;  1DKI A;  1DF0 A;  4BOZ A;  3PHX A;  1EWL A;  2BTW B;  4PAD A;  1MS6 A;  1AIM A;  3K24 A;  2G8E A;  2DC8 A;  4RNA A;  4YYR A;  1KFX L;  2IPP B;  5E6J A;  4X6H A;  1ME4 A;  3QJ3 A;  2Y6E A;  1JQP A;  3BC3 A;  3MP2 A;  2R6N A;  4GUA A;  3WXE A;  3PHU A;  4QRX A;  3V6E A;  2GHU A;  1KHQ A;  1GMY A;  3BPM A;  3KSE A;  5JA7 A;  2H7J A;  2G6D A;  4QRV A;  3PSE A;  4YVA A;  3M99 A;  4P6E A;  4HXD B;  2FQ9 A;  4OVZ A;  1PXV A;  3TRK A;  1F2C A;  1U9Q X;  5EF4 A;  1PCI A;  4BSQ A;  2VHS A;  2G8J A;  4BOP A;  4FK5 A;  3MHH A;  1AYW A;  5F02 A;  3BBA A;  2XU3 A;  2DJF B;  4Q8G A;  4ZUX U;  1BQI A;  4FJC A;  3GCB A;  1U5I A;  2OP3 A;  5CVO B;  1IWD A;  2VHF A;  3S3R A;  1AU2 A;  2P0R A;  1BP4 A;  1M6D A;  1DEU A;  2AYO A;  3MTV A;  4P16 A;  2HD5 A;  3H89 A;  1CPJ A;  2AVW A;  3HD3 A;  2DZY A;  3IOQ A;  3TNX A;  1ITO A;  1CVZ A;  2BDZ A;  3HWN A;  3CH3 X;  1SNK A;  1VSN A;  1AYU A;  3CH2 X;  1Y08 A;  3PRP A;  3U8E A;  5J94 A;  3P5X A;  1AU0 A;  3V6C A;  5CVN B;  1EWM A;  2E00 A;  3PNR A;  4YYV A;  1F2A A;  5JZE A;  2NQD B;  1PPO A;  2O6X A;  2YJ8 A;  3IV2 A;  1AU4 A;  2AS8 A;  4AXM A;  1GLO A;  3B21 A;  3K8U A;  3N3K A;  3TMP A;  4G54 A;  7PCK A;  2GFO A;  1QDQ A;  4RF1 A;  1ATK A;  2HHN A;  1XKG A;  1F2B A;  2AYN A;  2YJC A;  1BY8 A;  2YJ9 A;  3KWZ A;  4CZW A;  3NHE A;  3KW9 A;  3OVZ A;  1Y4H A;  4YYU A;  1F29 A;  4D8E A;  3N4C A;  1MEG A;  3D6S A;  3KWB X;  2Y5B A;  3BPF A;  1CB5 A;  4N79 A;  3PT2 A;  3DF0 A;  1CJL A;  1U9X A;  2DCA A;  3ZNH A;  3WXF A;  4I05 A;  1STF E;  4BS5 A;  2DC9 A;  3CBJ A;  2J7Q A;  3O65 A;  2XU5 A;  2UZJ A;  3MOR A;  2R9N A;  3ERV A;  2NQG A;  4REZ A;  1EWP A;  3IMA A;  1AU3 A;  4R3D A;  1MHW A;  1QOL A;  1NB5 A;  1TLO A;  3BWK A;  1KFU L;  2OZ2 A;  3OIS A;  3WXG A;  3K9M A;  2ACT A;  1CTE A;  2CB5 A;  3IEJ A;  3KX1 A;  3RVW A;  3C9E A;  2E02 A;  3QSD A;  3LFY A;  1POP A;  3W30 A;  4IUM A;  2AUZ A; 
#chains in the Genus database with same CATH homology
 3BOW A;  3H8B A;  3HHI A;  3MTN A;  3H6S A;  3B79 A;  2CIO A;  1EF7 A;  4C5P A;  1GCB A;  1A6R A;  2YJB A;  1PPD A;  3MHS A;  1YVB A;  2E01 A;  3I06 A;  3LXS A;  4CDC B;  1ZCM A;  2AIM A;  4N8W A;  2ARY A;  2DZZ A;  4X6J A;  2IBI A;  1AEC A;  1FH0 A;  3IUT A;  2DCC A;  1QXP A;  2AUX A;  4CDD B;  2JQG R;  2HH5 A;  4RY2 A;  1YAL A;  2WBF X;  1ICF A;  4Q8H A;  1YK7 A;  4P6G A;  2DC6 A;  4DMY A;  2XU1 A;  4I04 A;  1QMY A;  3P5V A;  4PI3 A;  1HUC B;  3BCN A;  2PAD A;  3O1G A;  8PCH A;  1GX3 A;  2YJ2 A;  3OF9 A;  2FUD A;  1CSB B;  1U9W A;  5PAD A;  3QT4 A;  1YK8 A;  1CQD A;  3USV A;  2FO5 A;  1NB3 A;  2C0Y A;  1ME3 A;  2ATO A;  2G7Y A;  5FPW A;  4WA6 A;  3RVV A;  3KFQ A;  2P7U A;  4QRG A;  3F5V A;  2XU4 A;  2E03 A;  3E1Z B;  1BGO A;  4AXL A;  4K7C A;  4W5B A;  1W4T A;  3OF8 A;  5CHV A;  4YV8 A;  3H8C A;  1MEM A;  1NPZ A;  1E2T A;  1KHP A;  4OEM A;  5CVM A;  2FRA A;  4BGF A;  1VJV A;  4W4U A;  4W5C A;  2P86 A;  5CHT A;  2R9F A;  1PAD A;  1YT7 A;  2BSZ A;  1AYV A;  5K16 A;  2R9C A;  9PAP A;  3KKU A;  2BDL A;  4MZO A;  2FYE A;  2NQI A;  1PBH A;  4KLB A;  2F1G A;  4QH6 A;  4YYW A;  1NQC A;  3H7D A;  1PE6 A;  4CDF B;  4X6I A;  2AU1 A;  1PPP A;  1EWO A;  2DJG B;  3PW3 A;  4HWY A;  2PBH A;  1U9V A;  2R9M A;  4YYS A;  1NL6 A;  3O0U A;  3PDF A;  2HXZ A;  1W6F A;  3S3Q A;  4PP1 A;  1MDW A;  3F75 A;  3CBK A;  4MZS A;  1CV8 A;  3P5U A;  2DCD A;  2PRE A;  1ZIV A;  2PNS A;  4QBB A;  1TL9 A;  2FTD A;  1O0E A;  2OUL A;  1K3B B;  1Q6K A;  2FT2 A;  2DCB A;  4CDE B;  4GUZ A;  4BPV A;  2VFC A;  1THE A;  4I07 A;  3N3G A;  1S4V A;  1NLJ A;  1TU6 A;  4DMX A;  2NQA A;  3RVX A;  3HHA A;  1PIP A;  1GEC E;  4BQV A;  1PPN A;  2B1N A;  1SP4 B;  2DC7 A;  2JQF R;  2FRQ A;  1X9Y A;  5EGW A;  1MIR A;  2VFB A;  4FIP A;  4OEL A;  5JH3 A;  3OVX A;  2R9O A;  4XR7 A;  3ZUA A;  3P5W A;  4MSX A;  3IHP A;  1CS8 A;  6PAD A;  4YYQ A;  4BS6 A;  4N4Z A;  4PP2 E;  4XUI A;  5A24 A;  3AI8 A;  1KXR A;  3I3T A;  2B1M A;  2F7D A;  3PBH A;  1DF0 A;  1EWL A;  4PAD A;  1MS6 A;  1AIM A;  3K24 A;  2G8E A;  2DC8 A;  3D9W A;  4YYR A;  1KFX L;  2IPP B;  3LTW A;  1ME4 A;  3QJ3 A;  4X6H A;  2Y6E A;  1JQP A;  3BC3 A;  1W5R A;  2R6N A;  3WXE A;  4QRX A;  3V6E A;  2GHU A;  1KHQ A;  1GMY A;  3BPM A;  3KSE A;  5JA7 A;  2H7J A;  2G6D A;  4QRV A;  4YVA A;  3M99 A;  4P6E A;  2FQ9 A;  1PXV A;  1F2C A;  1U9Q X;  5EF4 A;  1PCI A;  4BSQ A;  2VHS A;  2G8J A;  4FK5 A;  3MHH A;  1AYW A;  5F02 A;  2XU3 A;  2DJF B;  4Q8G A;  4ZUX U;  1BQI A;  4FJC A;  3GCB A;  1U5I A;  2OP3 A;  5CVO B;  1IWD A;  2VHF A;  3S3R A;  1AU2 A;  2P0R A;  1BP4 A;  1M6D A;  1DEU A;  2AYO A;  2HD5 A;  3H89 A;  1CPJ A;  2AVW A;  3HD3 A;  2DZY A;  3IOQ A;  3TNX A;  1ITO A;  1CVZ A;  2BDZ A;  3HWN A;  3CH3 X;  1SNK A;  1VSN A;  1AYU A;  3CH2 X;  1Y08 A;  3U8E A;  5J94 A;  3P5X A;  1AU0 A;  3V6C A;  5CVN B;  4NV8 A;  1EWM A;  2E00 A;  3PNR A;  4YYV A;  1F2A A;  2NQD B;  1PPO A;  2O6X A;  2YJ8 A;  3IV2 A;  1AU4 A;  2AS8 A;  4AXM A;  1GLO A;  3K8U A;  3N3K A;  4G54 A;  7PCK A;  2GFO A;  1QDQ A;  1ATK A;  4B55 A;  2HHN A;  1XKG A;  1F2B A;  2AYN A;  2YJC A;  1BY8 A;  2YJ9 A;  3KWZ A;  4CZW A;  3NHE A;  3KW9 A;  3OVZ A;  1Y4H A;  4YYU A;  1F29 A;  3N4C A;  1MEG A;  3D6S A;  3KWB X;  2Y5B A;  3BPF A;  1CB5 A;  4N79 A;  3DF0 A;  1CJL A;  1U9X A;  2DCA A;  3WXF A;  4NV7 A;  4I05 A;  1STF E;  4BS5 A;  2DC9 A;  3CBJ A;  2XU5 A;  3MOR A;  2R9N A;  3ERV A;  2NQG A;  1EWP A;  3IMA A;  1AU3 A;  1MHW A;  1QOL A;  1NB5 A;  1TLO A;  3BWK A;  1KFU L;  2OZ2 A;  3OIS A;  3WXG A;  3K9M A;  2ACT A;  1CTE A;  2CB5 A;  3IEJ A;  3KX1 A;  3RVW A;  3C9E A;  3QSD A;  2E02 A;  3LFY A;  1POP A;  2AUZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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