2G8EA

Calpain 1 proteolytic core in complex with snj-1715, a cyclic hemiacetal-type inhibitor
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
326
structure length
326
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLTPDLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Calpain Inhibition by alpha-Ketoamide and Cyclic Hemiacetal Inhibitors Revealed by X-ray Crystallography
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 100
structure length 326
sequence length 326
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2g8eA02
2FQ9A 3PDFA 4XUIA 1GMYA 1AYVA 2BDLA 2CB5A 1HUCB 5F02A 3KW9A 2CIOA 2DJFB 4RY2A 4DMYA 1S4VA 1X9YA 4G54A 3BCNA 1PE6A 4CDEB 5JH3A 2YJ8A 5FPWA 3OF8A 3BWKA 4FIPA 1SNKA 4P6GA 2XU4A 2FO5A 4N8WA 4CDDB 1GCBA 3MHHA 1VSNA 2DCBA 3IUTA 4QRXA 2F7DA 1TLOA 2R9CA 1XKGA 4YYQA 1CJLA 1YK8A 4MZSA 1KXRA 1U5IA 3E1ZB 3KFQA 2IBIA 2BDZA 1SP4B 2FUDA 2OULA 5CVNB 2P7UA 1ICFA 3HHIA 3ZUAA 2H7JA 3H7DA 4YYWA 1IWDA 3H89A 2XU1A 3D6SA 5JA7A 2WBFX 4CDCB 4FJCA 2IPPB 5K16A 2AUZA 3OISA 1PPDA 3WXGA 2HHNA 2Y5BA 4PI3A 3IHPA 3M99A 4QRVA 1AU4A 3MTNA 2B1MA 1EWPA 2R9NA 3RVVA 1KHPA 2GHUA 3KX1A 4W4UA 2G8JA 1VJVA 4QRGA 1CTEA 4QBBA 3IMAA 4YYUA 2P86A 4N4ZA 1F2CA 2P0RA 4I04A 1ZCMA 3GCBA 2OP3A 3B79A 1CQDA 4OELA 1ZIVA 4AXLA 1QMYA 2FTDA 3V6CA 3RVWA 2ATOA 2XU3A 2DC8A 4Q8HA 2PADA 1QOLA 1BP4A 2DC7A 6PADA 3N3KA 3K8UA 3IEJA 3QSDA 1U9QX 4BQVA 3WXEA 2NQDB 1ME3A 1MIRA 1QDQA 1U9VA 4YYSA 4AXMA 1EWOA 3C9EA 1O0EA 2GFOA 3CBKA 3NHEA 5CVOB 2DCCA 7PCKA 1BQIA 2FYEA 5CVMA 2OZ2A 3I3TA 3H8CA 3H6SA 4X6HA 2JQFR 1PPNA 2NQAA 1A6RA 2E03A 1KHQA 4HWYA 4CDFB 1PIPA 1Y4HA 1ME4A 3BPFA 1AECA 2AS8A 4W5CA 4YVAA 2NQIA 1MEMA 4ZUXU 4BS5A 3RVXA 3V6EA 1YALA 4YYRA 4YYVA 2DC9A 1AU0A 3S3QA 4BS6A 2AU1A 3F75A 2ARYA 1CSBB 3HHAA 4BSQA 3K9MA 2Y6EA 3IOQA 1NPZA 2VHSA 3BOWA 2ACTA 2G6DA 4PP1A 3HWNA 1NL6A 3AI8A 2FT2A 2E02A 1NLJA 1FH0A 4MSXA 4WA6A 1BGOA 3PW3A 2AYOA 3QJ3A 3BPMA 1DF0A 1JQPA 4Q8GA 2R9MA 3CH2X 3HD3A 3KWBX 3TNXA 2YJ2A 2HD5A 5A24A 3O0UA 1EWMA 1TU6A 1EF7A 1MS6A 1YT7A 3CBJA 1PPPA 1PPOA 2R9FA 3MORA 1PCIA 2FRQA 2VHFA 2JQGR 2HH5A 2R9OA 2R6NA 3I06A 3KWZA 4X6IA 3K24A 8PCHA 1MHWA 4N79A 9PAPA 4K7CA 1K3BB 1F2AA 4PADA 2PBHA 2DC6A 3ERVA 2O6XA 1U9WA 3KSEA 3OVZA 1PADA 1CV8A 3DF0A 1KFUL 3P5XA 5J94A 1CPJA 1F2BA 1YK7A 3PNRA 2PNSA 5CHTA 3LXSA 1YVBA 2AVWA 4KLBA 1F29A 3P5VA 4YV8A 1PBHA 2DCAA 2B1NA 3N4CA 2YJCA 1AYWA 2DCDA 4OEMA 3MHSA 1THEA 1ATKA 2F1GA 2FRAA 4I05A 2AYNA 1TL9A 1EWLA 1GECE 5EF4A 3P5WA 3PBHA 3N3GA 2C0YA 1QXPA 2DZYA 2DZZA 2E00A 1AU3A 2YJBA 2XU5A 3BC3A 5CHVA 1PXVA 4FK5A 1ITOA 4XR7A 1MDWA 2HXZA 4BPVA 2E01A 3WXFA 2YJ9A 3QT4A 1KFXL 4MZOA 2G8EA 1DEUA 2DJGB 3CH3X 1M6DA 2NQGA 1GLOA 1Q6KA 3F5VA 4X6JA 3P5UA 4DMXA 3O1GA 1NB3A 2AIMA 3LFYA 3OF9A 3USVA 1AU2A 1CS8A 1MEGA 2G7YA 1BY8A 1Y08A 1NQCA 1STFE 4I07A 3H8BA 4CZWA 5PADA 5EGWA 4QH6A 2PREA 3S3RA 1U9XA 4P6EA 1CVZA 3IV2A 1AIMA 2AUXA 1POPA 3OVXA 3KKUA 3U8EA 1CB5A 4PP2E 4W5BA 1NB5A 1AYUA
chains in the Genus database with same CATH superfamily
2FQ9A 3PDFA 4XUIA 1GMYA 4BOUA 1AYVA 2BDLA 2CB5A 1HUCB 5F02A 3KW9A 2CIOA 2DJFB 4RY2A 4DMYA 1S4VA 2J7QC 4D8BA 1X9YA 4G54A 3BCNA 1PE6A 4CDEB 3W30A 5JH3A 2YJ8A 5FPWA 3OF8A 3BWKA 4FIPA 1SNKA 4P6GA 2XU4A 2FO5A 4N8WA 4CDDB 1GCBA 3MHHA 4MI7A 1VSNA 2DCBA 3IUTA 4MM3B 4BOQA 4QRXA 2F7DA 1TLOA 2R9CA 1XKGA 4YYQA 1CJLA 1YK8A 4RKXA 4MZSA 1KXRA 1U5IA 3C0RA 3BY4A 3E1ZB 3PSEA 3KFQA 2IBIA 2BDZA 1SP4B 2FUDA 2OULA 5CVNB 2P7UA 1ICFA 3BBAA 3HHIA 3ZUAA 2H7JA 3H7DA 4YYWA 4RNAA 1IWDA 3H89A 2XU1A 3D6SA 2DOSA 5JA7A 2WBFX 4CDCB 4BOSA 4FJCA 2IPPB 5K16A 2AUZA 3OISA 1PPDA 3WXGA 2Z84A 2HHNA 2Y5BA 3M99A 3IHPA 4PI3A 4QRVA 1AU4A 5EZQA 3MTNA 3E9SA 2B1MA 4IUMA 1EWPA 3PHUA 2R9NA 3RVVA 1KHPA 2GHUA 3KX1A 3MJ5A 4W4UA 5EZSA 2G8JA 1VJVA 4QRGA 1CTEA 4QBBA 3W31A 3IMAA 4YYUA 2P86A 4N4ZA 1F2CA 2FE8A 4WURA 2P0RA 4I04A 1ZCMA 1UKFA 3GCBA 2OP3A 3IFUA 1PVJA 3B79A 1CQDA 4OELA 1ZIVA 4AXLA 1QMYA 2FTDA 3V6CA 3RVWA 2ATOA 2XU3A 2DC8A 4Q8HA 3PT2A 2PADA 4XZXA 1QOLA 1BP4A 2DC7A 6PADA 3N3KA 3K8UA 2BU3A 3IEJA 3QSDA 1U9QX 4BQVA 3MP2A 3WXEA 2NQDB 1ME3A 1MIRA 1QDQA 1U9VA 4YYSA 4AXMA 2JRIA 1EWOA 3C9EA 1O0EA 2GFOA 3CBKA 3NHEA 5CVOB 2DCCA 7PCKA 3B21A 1BQIA 2FYEA 5CVMA 2OZ2A 5E6JA 3I3TA 3H8CA 3H6SA 4OVZA 4X6HA 2JQFR 1PPNA 2AGAA 2NQAA 1A6RA 2E03A 1KHQA 4HWYA 4CDFB 1PIPA 5JZEA 2JTCA 1Y4HA 1ME4A 3BPFA 1AECA 2AS8A 4W5CA 4YVAA 2NQIA 1MEMA 4ZUXU 4P16A 4BS5A 3RVXA 3V6EA 1YALA 4YYRA 4YYVA 2DC9A 1AU0A 3S3QA 4BS6A 2AU1A 3F75A 3PHXA 2ARYA 1CSBB 3HHAA 4BSQA 3K9MA 2Y6EA 3IOQA 1NPZA 2VHSA 4GUAA 3BOWA 4D8IA 2ACTA 2G6DA 4PP1A 3HWNA 1NL6A 3AI8A 2FT2A 2E02A 1NLJA 1FH0A 4MSXA 4WA6A 2BTWA 1BGOA 4D8EA 4OVZB 3PW3A 2AYOA 3QJ3A 3BPMA 1DF0A 1JQPA 4Q8GA 4REZA 2R9MA 3CH2X 3RNVA 3HD3A 3KWBX 3TNXA 2YJ2A 2HD5A 5A24A 3O0UA 4BOZA 4RF1A 1EWMA 1TU6A 1EF7A 1MS6A 1YT7A 3PRMA 3CBJA 1PPPA 1PPOA 4M0WA 2R9FA 3MORA 1PCIA 2FRQA 2VHFA 2JQGR 2HH5A 2UZJA 2R9OA 3KWZA 2R6NA 3I06A 4X6IA 3ZNHA 3K24A 3TRKA 8PCHA 3OQCA 1MHWA 4N79A 9PAPA 4K7CA 1K3BB 1F2AA 4PADA 2PBHA 2DC6A 3ERVA 2O6XA 1U9WA 3KSEA 3OVZA 1PADA 1CV8A 3DF0A 1KFUL 3P5XA 5J94A 3MTVA 1CPJA 1F2BA 1YK7A 3PNRA 2PNSA 4ZTBA 5CHTA 1YZBA 3LXSA 1YVBA 2AVWA 4KLBA 2BTWB 1F29A 3TMPA 3P5VA 4YV8A 4HXDB 1PBHA 2DCAA 2B1NA 3N4CA 2YJCA 1AYWA 2DCDA 4OEMA 3MHSA 1THEA 1ATKA 2F1GA 2FRAA 4I05A 2AYNA 1TL9A 1EWLA 1GECE 5EF4A 4A5UA 3P5WA 3PBHA 4OW0A 3N3GA 2C0YA 1QXPA 2DZYA 2DZZA 2E00A 1AU3A 2YJBA 2XU5A 3BC3A 5CHVA 1PXVA 4FK5A 1ITOA 4XR7A 1MDWA 2HXZA 4BPVA 3O65A 2E01A 5KO3A 3WXFA 3BB7A 4IP3A 2YJ9A 3QT4A 1KFXL 4MZOA 2G8EA 2J7QA 1DEUA 2DJGB 3CH3X 3PHWA 1M6DA 2NQGA 1GLOA 1Q6KA 3F5VA 4X6JA 3P5UA 4DMXA 3O1GA 1NB3A 2AIMA 3LFYA 3OF9A 4R3DA 3USVA 1AU2A 1CS8A 1MEGA 3PRPA 4BOPA 2G7YA 1BY8A 1Y08A 1NQCA 1STFE 4I07A 3H8BA 4RF0A 5PADA 5EGWA 4CZWA 4QH6A 2PREA 1DKIA 1U9XA 3S3RA 4P6EA 1CVZA 2HWKA 3IV2A 1AIMA 2AUXA 1POPA 3OVXA 3KKUA 3U8EA 1CB5A 4PP2E 4PT5A 4W5BA 1NB5A 1AYUA
chains in the Genus database with same CATH topology
2FQ9A 3PDFA 4XUIA 1GMYA 1AYVA 2BDLA 2CB5A 1HUCB 5F02A 3KW9A 2CIOA 2DJFB 4RY2A 4DMYA 1S4VA 1X9YA 4G54A 3BCNA 1PE6A 4CDEB 5JH3A 2YJ8A 5FPWA 3LTWA 3OF8A 3BWKA 4FIPA 1SNKA 4P6GA 2XU4A 2FO5A 4N8WA 4CDDB 1GCBA 3MHHA 1VSNA 2DCBA 3IUTA 4QRXA 2F7DA 1TLOA 4GUZA 2R9CA 1XKGA 4YYQA 1CJLA 1YK8A 4MZSA 1KXRA 1U5IA 3E1ZB 3KFQA 2IBIA 2BDZA 1SP4B 2FUDA 2OULA 5CVNB 2P7UA 1ICFA 3HHIA 3ZUAA 2H7JA 3H7DA 4YYWA 1IWDA 3H89A 2XU1A 3D6SA 4B55A 2VFBA 5JA7A 2WBFX 4CDCB 4FJCA 2IPPB 5K16A 2AUZA 3OISA 1PPDA 3WXGA 2HHNA 2Y5BA 3M99A 3IHPA 4PI3A 4QRVA 1AU4A 3MTNA 2B1MA 1EWPA 2R9NA 3RVVA 1E2TA 1KHPA 2GHUA 3KX1A 4W4UA 4NV8A 2G8JA 1VJVA 4QRGA 1CTEA 4QBBA 3IMAA 4YYUA 2P86A 4N4ZA 1F2CA 2P0RA 1GX3A 4I04A 1ZCMA 3GCBA 2OP3A 1W5RA 3B79A 1CQDA 4OELA 1ZIVA 4AXLA 1QMYA 2FTDA 3V6CA 3RVWA 2ATOA 2XU3A 2DC8A 4Q8HA 2PADA 3D9WA 1QOLA 1BP4A 2DC7A 6PADA 3N3KA 3K8UA 3IEJA 3QSDA 1U9QX 4BQVA 3WXEA 2NQDB 1ME3A 1MIRA 1QDQA 1U9VA 4YYSA 4AXMA 1EWOA 3C9EA 1O0EA 2GFOA 3CBKA 3NHEA 5CVOB 2DCCA 7PCKA 1BQIA 2FYEA 5CVMA 4BGFA 2OZ2A 3I3TA 3H8CA 3H6SA 4C5PA 4X6HA 2JQFR 1PPNA 2NQAA 1A6RA 2E03A 1KHQA 4HWYA 4CDFB 1PIPA 1Y4HA 1ME4A 3BPFA 1AECA 2AS8A 4W5CA 4YVAA 2NQIA 1MEMA 4ZUXU 4BS5A 3RVXA 3V6EA 1YALA 4YYRA 4YYVA 2DC9A 1AU0A 3S3QA 4BS6A 2AU1A 3F75A 2ARYA 1CSBB 3HHAA 4BSQA 3K9MA 2Y6EA 3IOQA 1NPZA 2VHSA 3BOWA 2ACTA 2G6DA 4PP1A 3HWNA 1NL6A 3AI8A 2FT2A 2VFCA 2E02A 1NLJA 1FH0A 4MSXA 4WA6A 1BGOA 3PW3A 2AYOA 3QJ3A 3BPMA 1DF0A 1JQPA 4Q8GA 2R9MA 3CH2X 3HD3A 3KWBX 3TNXA 2YJ2A 2HD5A 5A24A 3O0UA 1EWMA 1TU6A 1EF7A 1MS6A 1YT7A 3CBJA 1PPPA 1PPOA 2R9FA 3MORA 1PCIA 2FRQA 2VHFA 2JQGR 1W4TA 2HH5A 2R9OA 2R6NA 3I06A 3KWZA 4X6IA 3K24A 8PCHA 1MHWA 4N79A 9PAPA 4K7CA 1K3BB 1F2AA 4PADA 2PBHA 2DC6A 3ERVA 2O6XA 1U9WA 3KSEA 3OVZA 1PADA 1CV8A 3DF0A 1KFUL 3P5XA 5J94A 1CPJA 1F2BA 1YK7A 3PNRA 2PNSA 5CHTA 4NV7A 3LXSA 1YVBA 2AVWA 4KLBA 1F29A 3P5VA 4YV8A 1PBHA 2DCAA 2B1NA 3N4CA 2YJCA 1AYWA 2DCDA 4OEMA 3MHSA 1THEA 1ATKA 2F1GA 2FRAA 4I05A 2AYNA 1TL9A 1EWLA 1GECE 5EF4A 3P5WA 3PBHA 2BSZA 3N3GA 2C0YA 1QXPA 2DZYA 2DZZA 2E00A 1AU3A 2YJBA 2XU5A 3BC3A 5CHVA 1PXVA 4FK5A 1ITOA 4XR7A 1MDWA 2HXZA 4BPVA 2E01A 3WXFA 2YJ9A 3QT4A 1KFXL 4MZOA 2G8EA 1DEUA 2DJGB 3CH3X 1M6DA 2NQGA 1GLOA 1Q6KA 3F5VA 4X6JA 3P5UA 4DMXA 3O1GA 1NB3A 2AIMA 3LFYA 3OF9A 3USVA 1AU2A 1CS8A 1MEGA 2G7YA 1BY8A 1Y08A 1NQCA 1STFE 4I07A 3H8BA 4CZWA 5PADA 5EGWA 4QH6A 2PREA 3S3RA 1U9XA 4P6EA 1CVZA 1W6FA 3IV2A 1AIMA 2AUXA 1POPA 3OVXA 3KKUA 3U8EA 1CB5A 4PP2E 4W5BA 1NB5A 1AYUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FQ9 A;  3PDF A;  4XUI A;  1GMY A;  1AYV A;  2BDL A;  2CB5 A;  1HUC B;  5F02 A;  3KW9 A;  2CIO A;  2DJF B;  4RY2 A;  4DMY A;  1S4V A;  1X9Y A;  4G54 A;  3BCN A;  1PE6 A;  4CDE B;  5JH3 A;  2YJ8 A;  5FPW A;  3OF8 A;  3BWK A;  4FIP A;  1SNK A;  4P6G A;  2XU4 A;  2FO5 A;  4N8W A;  4CDD B;  1GCB A;  3MHH A;  1VSN A;  2DCB A;  3IUT A;  4QRX A;  2F7D A;  1TLO A;  2R9C A;  1XKG A;  4YYQ A;  1CJL A;  1YK8 A;  4MZS A;  1KXR A;  1U5I A;  3E1Z B;  3KFQ A;  2IBI A;  2BDZ A;  1SP4 B;  2FUD A;  2OUL A;  5CVN B;  2P7U A;  1ICF A;  3HHI A;  3ZUA A;  2H7J A;  3H7D A;  4YYW A;  1IWD A;  3H89 A;  2XU1 A;  3D6S A;  5JA7 A;  2WBF X;  4CDC B;  4FJC A;  2IPP B;  5K16 A;  2AUZ A;  3OIS A;  1PPD A;  3WXG A;  2HHN A;  2Y5B A;  4PI3 A;  3IHP A;  3M99 A;  4QRV A;  1AU4 A;  3MTN A;  2B1M A;  1EWP A;  2R9N A;  3RVV A;  1KHP A;  2GHU A;  3KX1 A;  4W4U A;  2G8J A;  1VJV A;  4QRG A;  1CTE A;  4QBB A;  3IMA A;  4YYU A;  2P86 A;  4N4Z A;  1F2C A;  2P0R A;  4I04 A;  1ZCM A;  3GCB A;  2OP3 A;  3B79 A;  1CQD A;  4OEL A;  1ZIV A;  4AXL A;  1QMY A;  2FTD A;  3V6C A;  3RVW A;  2ATO A;  2XU3 A;  2DC8 A;  4Q8H A;  2PAD A;  1QOL A;  1BP4 A;  2DC7 A;  6PAD A;  3N3K A;  3K8U A;  3IEJ A;  3QSD A;  1U9Q X;  4BQV A;  3WXE A;  2NQD B;  1ME3 A;  1MIR A;  1QDQ A;  1U9V A;  4YYS A;  4AXM A;  1EWO A;  3C9E A;  1O0E A;  2GFO A;  3CBK A;  3NHE A;  5CVO B;  2DCC A;  7PCK A;  1BQI A;  2FYE A;  5CVM A;  2OZ2 A;  3I3T A;  3H8C A;  3H6S A;  4X6H A;  2JQF R;  1PPN A;  2NQA A;  1A6R A;  2E03 A;  1KHQ A;  4HWY A;  4CDF B;  1PIP A;  1Y4H A;  1ME4 A;  3BPF A;  1AEC A;  2AS8 A;  4W5C A;  4YVA A;  2NQI A;  1MEM A;  4ZUX U;  4BS5 A;  3RVX A;  3V6E A;  1YAL A;  4YYR A;  4YYV A;  2DC9 A;  1AU0 A;  3S3Q A;  4BS6 A;  2AU1 A;  3F75 A;  2ARY A;  1CSB B;  3HHA A;  4BSQ A;  3K9M A;  2Y6E A;  3IOQ A;  1NPZ A;  2VHS A;  3BOW A;  2ACT A;  2G6D A;  4PP1 A;  3HWN A;  1NL6 A;  3AI8 A;  2FT2 A;  2E02 A;  1NLJ A;  1FH0 A;  4MSX A;  4WA6 A;  1BGO A;  3PW3 A;  2AYO A;  3QJ3 A;  3BPM A;  1DF0 A;  1JQP A;  4Q8G A;  2R9M A;  3CH2 X;  3HD3 A;  3KWB X;  3TNX A;  2YJ2 A;  2HD5 A;  5A24 A;  3O0U A;  1EWM A;  1TU6 A;  1EF7 A;  1MS6 A;  1YT7 A;  3CBJ A;  1PPP A;  1PPO A;  2R9F A;  3MOR A;  1PCI A;  2FRQ A;  2VHF A;  2JQG R;  2HH5 A;  2R9O A;  2R6N A;  3I06 A;  3KWZ A;  4X6I A;  3K24 A;  8PCH A;  1MHW A;  4N79 A;  9PAP A;  4K7C A;  1K3B B;  1F2A A;  4PAD A;  2PBH A;  2DC6 A;  3ERV A;  2O6X A;  1U9W A;  3KSE A;  3OVZ A;  1PAD A;  1CV8 A;  3DF0 A;  1KFU L;  3P5X A;  5J94 A;  1CPJ A;  1F2B A;  1YK7 A;  3PNR A;  2PNS A;  5CHT A;  3LXS A;  1YVB A;  2AVW A;  4KLB A;  1F29 A;  3P5V A;  4YV8 A;  1PBH A;  2DCA A;  2B1N A;  3N4C A;  2YJC A;  1AYW A;  2DCD A;  4OEM A;  3MHS A;  1THE A;  1ATK A;  2F1G A;  2FRA A;  4I05 A;  2AYN A;  1TL9 A;  1EWL A;  1GEC E;  5EF4 A;  3P5W A;  3PBH A;  3N3G A;  2C0Y A;  1QXP A;  2DZY A;  2DZZ A;  2E00 A;  1AU3 A;  2YJB A;  2XU5 A;  3BC3 A;  5CHV A;  1PXV A;  4FK5 A;  1ITO A;  4XR7 A;  1MDW A;  2HXZ A;  4BPV A;  2E01 A;  3WXF A;  2YJ9 A;  3QT4 A;  1KFX L;  4MZO A;  2G8E A;  1DEU A;  2DJG B;  3CH3 X;  1M6D A;  2NQG A;  1GLO A;  1Q6K A;  3F5V A;  4X6J A;  3P5U A;  4DMX A;  3O1G A;  1NB3 A;  2AIM A;  3LFY A;  3OF9 A;  3USV A;  1AU2 A;  1CS8 A;  1MEG A;  2G7Y A;  1BY8 A;  1Y08 A;  1NQC A;  1STF E;  4I07 A;  3H8B A;  4CZW A;  5PAD A;  5EGW A;  4QH6 A;  2PRE A;  3S3R A;  1U9X A;  4P6E A;  1CVZ A;  3IV2 A;  1AIM A;  2AUX A;  1POP A;  3OVX A;  3KKU A;  3U8E A;  1CB5 A;  4PP2 E;  4W5B A;  1NB5 A;  1AYU A; 
#chains in the Genus database with same CATH topology
 2FQ9 A;  3PDF A;  4XUI A;  1GMY A;  4BOU A;  1AYV A;  2BDL A;  2CB5 A;  1HUC B;  5F02 A;  3KW9 A;  2CIO A;  2DJF B;  4RY2 A;  4DMY A;  1S4V A;  2J7Q C;  4D8B A;  1X9Y A;  4G54 A;  3BCN A;  1PE6 A;  4CDE B;  3W30 A;  5JH3 A;  2YJ8 A;  5FPW A;  3OF8 A;  3BWK A;  4FIP A;  1SNK A;  4P6G A;  2XU4 A;  2FO5 A;  4N8W A;  4CDD B;  1GCB A;  3MHH A;  4MI7 A;  1VSN A;  2DCB A;  3IUT A;  4MM3 B;  4BOQ A;  4QRX A;  2F7D A;  1TLO A;  2R9C A;  1XKG A;  4YYQ A;  1CJL A;  1YK8 A;  4RKX A;  4MZS A;  1KXR A;  1U5I A;  3C0R A;  3BY4 A;  3E1Z B;  3PSE A;  3KFQ A;  2IBI A;  2BDZ A;  1SP4 B;  2FUD A;  2OUL A;  5CVN B;  2P7U A;  1ICF A;  3BBA A;  3HHI A;  3ZUA A;  2H7J A;  3H7D A;  4YYW A;  4RNA A;  1IWD A;  3H89 A;  2XU1 A;  3D6S A;  2DOS A;  5JA7 A;  2WBF X;  4CDC B;  4BOS A;  4FJC A;  2IPP B;  5K16 A;  2AUZ A;  3OIS A;  1PPD A;  3WXG A;  2Z84 A;  2HHN A;  2Y5B A;  3M99 A;  3IHP A;  4PI3 A;  4QRV A;  1AU4 A;  5EZQ A;  3MTN A;  3E9S A;  2B1M A;  4IUM A;  1EWP A;  3PHU A;  2R9N A;  3RVV A;  1KHP A;  2GHU A;  3KX1 A;  3MJ5 A;  4W4U A;  5EZS A;  2G8J A;  1VJV A;  4QRG A;  1CTE A;  4QBB A;  3W31 A;  3IMA A;  4YYU A;  2P86 A;  4N4Z A;  1F2C A;  2FE8 A;  4WUR A;  2P0R A;  4I04 A;  1ZCM A;  1UKF A;  3GCB A;  2OP3 A;  3IFU A;  1PVJ A;  3B79 A;  1CQD A;  4OEL A;  1ZIV A;  4AXL A;  1QMY A;  2FTD A;  3V6C A;  3RVW A;  2ATO A;  2XU3 A;  2DC8 A;  4Q8H A;  3PT2 A;  2PAD A;  4XZX A;  1QOL A;  1BP4 A;  2DC7 A;  6PAD A;  3N3K A;  3K8U A;  2BU3 A;  3IEJ A;  3QSD A;  1U9Q X;  4BQV A;  3MP2 A;  3WXE A;  2NQD B;  1ME3 A;  1MIR A;  1QDQ A;  1U9V A;  4YYS A;  4AXM A;  2JRI A;  1EWO A;  3C9E A;  1O0E A;  2GFO A;  3CBK A;  3NHE A;  5CVO B;  2DCC A;  7PCK A;  3B21 A;  1BQI A;  2FYE A;  5CVM A;  2OZ2 A;  5E6J A;  3I3T A;  3H8C A;  3H6S A;  4OVZ A;  4X6H A;  2JQF R;  1PPN A;  2AGA A;  2NQA A;  1A6R A;  2E03 A;  1KHQ A;  4HWY A;  4CDF B;  1PIP A;  5JZE A;  2JTC A;  1Y4H A;  1ME4 A;  3BPF A;  1AEC A;  2AS8 A;  4W5C A;  4YVA A;  2NQI A;  1MEM A;  4ZUX U;  4P16 A;  4BS5 A;  3RVX A;  3V6E A;  1YAL A;  4YYR A;  4YYV A;  2DC9 A;  1AU0 A;  3S3Q A;  4BS6 A;  2AU1 A;  3F75 A;  3PHX A;  2ARY A;  1CSB B;  3HHA A;  4BSQ A;  3K9M A;  2Y6E A;  3IOQ A;  1NPZ A;  2VHS A;  4GUA A;  3BOW A;  4D8I A;  2ACT A;  2G6D A;  4PP1 A;  3HWN A;  1NL6 A;  3AI8 A;  2FT2 A;  2E02 A;  1NLJ A;  1FH0 A;  4MSX A;  4WA6 A;  2BTW A;  1BGO A;  4D8E A;  4OVZ B;  3PW3 A;  2AYO A;  3QJ3 A;  3BPM A;  1DF0 A;  1JQP A;  4Q8G A;  4REZ A;  2R9M A;  3CH2 X;  3RNV A;  3HD3 A;  3KWB X;  3TNX A;  2YJ2 A;  2HD5 A;  5A24 A;  3O0U A;  4BOZ A;  4RF1 A;  1EWM A;  1TU6 A;  1EF7 A;  1MS6 A;  1YT7 A;  3PRM A;  3CBJ A;  1PPP A;  1PPO A;  4M0W A;  2R9F A;  3MOR A;  1PCI A;  2FRQ A;  2VHF A;  2JQG R;  2HH5 A;  2UZJ A;  2R9O A;  3KWZ A;  2R6N A;  3I06 A;  4X6I A;  3ZNH A;  3K24 A;  3TRK A;  8PCH A;  3OQC A;  1MHW A;  4N79 A;  9PAP A;  4K7C A;  1K3B B;  1F2A A;  4PAD A;  2PBH A;  2DC6 A;  3ERV A;  2O6X A;  1U9W A;  3KSE A;  3OVZ A;  1PAD A;  1CV8 A;  3DF0 A;  1KFU L;  3P5X A;  5J94 A;  3MTV A;  1CPJ A;  1F2B A;  1YK7 A;  3PNR A;  2PNS A;  4ZTB A;  5CHT A;  1YZB A;  3LXS A;  1YVB A;  2AVW A;  4KLB A;  2BTW B;  1F29 A;  3TMP A;  3P5V A;  4YV8 A;  4HXD B;  1PBH A;  2DCA A;  2B1N A;  3N4C A;  2YJC A;  1AYW A;  2DCD A;  4OEM A;  3MHS A;  1THE A;  1ATK A;  2F1G A;  2FRA A;  4I05 A;  2AYN A;  1TL9 A;  1EWL A;  1GEC E;  5EF4 A;  4A5U A;  3P5W A;  3PBH A;  4OW0 A;  3N3G A;  2C0Y A;  1QXP A;  2DZY A;  2DZZ A;  2E00 A;  1AU3 A;  2YJB A;  2XU5 A;  3BC3 A;  5CHV A;  1PXV A;  4FK5 A;  1ITO A;  4XR7 A;  1MDW A;  2HXZ A;  4BPV A;  3O65 A;  2E01 A;  5KO3 A;  3WXF A;  3BB7 A;  4IP3 A;  2YJ9 A;  3QT4 A;  1KFX L;  4MZO A;  2G8E A;  2J7Q A;  1DEU A;  2DJG B;  3CH3 X;  3PHW A;  1M6D A;  2NQG A;  1GLO A;  1Q6K A;  3F5V A;  4X6J A;  3P5U A;  4DMX A;  3O1G A;  1NB3 A;  2AIM A;  3LFY A;  3OF9 A;  4R3D A;  3USV A;  1AU2 A;  1CS8 A;  1MEG A;  3PRP A;  4BOP A;  2G7Y A;  1BY8 A;  1Y08 A;  1NQC A;  1STF E;  4I07 A;  3H8B A;  4RF0 A;  5PAD A;  5EGW A;  4CZW A;  4QH6 A;  2PRE A;  1DKI A;  1U9X A;  3S3R A;  4P6E A;  1CVZ A;  2HWK A;  3IV2 A;  1AIM A;  2AUX A;  1POP A;  3OVX A;  3KKU A;  3U8E A;  1CB5 A;  4PP2 E;  4PT5 A;  4W5B A;  1NB5 A;  1AYU A; 
#chains in the Genus database with same CATH homology
 2FQ9 A;  3PDF A;  4XUI A;  1GMY A;  1AYV A;  2BDL A;  2CB5 A;  1HUC B;  5F02 A;  3KW9 A;  2CIO A;  2DJF B;  4RY2 A;  4DMY A;  1S4V A;  1X9Y A;  4G54 A;  3BCN A;  1PE6 A;  4CDE B;  5JH3 A;  2YJ8 A;  5FPW A;  3LTW A;  3OF8 A;  3BWK A;  4FIP A;  1SNK A;  4P6G A;  2XU4 A;  2FO5 A;  4N8W A;  4CDD B;  1GCB A;  3MHH A;  1VSN A;  2DCB A;  3IUT A;  4QRX A;  2F7D A;  1TLO A;  4GUZ A;  2R9C A;  1XKG A;  4YYQ A;  1CJL A;  1YK8 A;  4MZS A;  1KXR A;  1U5I A;  3E1Z B;  3KFQ A;  2IBI A;  2BDZ A;  1SP4 B;  2FUD A;  2OUL A;  5CVN B;  2P7U A;  1ICF A;  3HHI A;  3ZUA A;  2H7J A;  3H7D A;  4YYW A;  1IWD A;  3H89 A;  2XU1 A;  3D6S A;  4B55 A;  2VFB A;  5JA7 A;  2WBF X;  4CDC B;  4FJC A;  2IPP B;  5K16 A;  2AUZ A;  3OIS A;  1PPD A;  3WXG A;  2HHN A;  2Y5B A;  3M99 A;  3IHP A;  4PI3 A;  4QRV A;  1AU4 A;  3MTN A;  2B1M A;  1EWP A;  2R9N A;  3RVV A;  1E2T A;  1KHP A;  2GHU A;  3KX1 A;  4W4U A;  4NV8 A;  2G8J A;  1VJV A;  4QRG A;  1CTE A;  4QBB A;  3IMA A;  4YYU A;  2P86 A;  4N4Z A;  1F2C A;  2P0R A;  1GX3 A;  4I04 A;  1ZCM A;  3GCB A;  2OP3 A;  1W5R A;  3B79 A;  1CQD A;  4OEL A;  1ZIV A;  4AXL A;  1QMY A;  2FTD A;  3V6C A;  3RVW A;  2ATO A;  2XU3 A;  2DC8 A;  4Q8H A;  2PAD A;  3D9W A;  1QOL A;  1BP4 A;  2DC7 A;  6PAD A;  3N3K A;  3K8U A;  3IEJ A;  3QSD A;  1U9Q X;  4BQV A;  3WXE A;  2NQD B;  1ME3 A;  1MIR A;  1QDQ A;  1U9V A;  4YYS A;  4AXM A;  1EWO A;  3C9E A;  1O0E A;  2GFO A;  3CBK A;  3NHE A;  5CVO B;  2DCC A;  7PCK A;  1BQI A;  2FYE A;  5CVM A;  4BGF A;  2OZ2 A;  3I3T A;  3H8C A;  3H6S A;  4C5P A;  4X6H A;  2JQF R;  1PPN A;  2NQA A;  1A6R A;  2E03 A;  1KHQ A;  4HWY A;  4CDF B;  1PIP A;  1Y4H A;  1ME4 A;  3BPF A;  1AEC A;  2AS8 A;  4W5C A;  4YVA A;  2NQI A;  1MEM A;  4ZUX U;  4BS5 A;  3RVX A;  3V6E A;  1YAL A;  4YYR A;  4YYV A;  2DC9 A;  1AU0 A;  3S3Q A;  4BS6 A;  2AU1 A;  3F75 A;  2ARY A;  1CSB B;  3HHA A;  4BSQ A;  3K9M A;  2Y6E A;  3IOQ A;  1NPZ A;  2VHS A;  3BOW A;  2ACT A;  2G6D A;  4PP1 A;  3HWN A;  1NL6 A;  3AI8 A;  2FT2 A;  2VFC A;  2E02 A;  1NLJ A;  1FH0 A;  4MSX A;  4WA6 A;  1BGO A;  3PW3 A;  2AYO A;  3QJ3 A;  3BPM A;  1DF0 A;  1JQP A;  4Q8G A;  2R9M A;  3CH2 X;  3HD3 A;  3KWB X;  3TNX A;  2YJ2 A;  2HD5 A;  5A24 A;  3O0U A;  1EWM A;  1TU6 A;  1EF7 A;  1MS6 A;  1YT7 A;  3CBJ A;  1PPP A;  1PPO A;  2R9F A;  3MOR A;  1PCI A;  2FRQ A;  2VHF A;  2JQG R;  1W4T A;  2HH5 A;  2R9O A;  2R6N A;  3I06 A;  3KWZ A;  4X6I A;  3K24 A;  8PCH A;  1MHW A;  4N79 A;  9PAP A;  4K7C A;  1K3B B;  1F2A A;  4PAD A;  2PBH A;  2DC6 A;  3ERV A;  2O6X A;  1U9W A;  3KSE A;  3OVZ A;  1PAD A;  1CV8 A;  3DF0 A;  1KFU L;  3P5X A;  5J94 A;  1CPJ A;  1F2B A;  1YK7 A;  3PNR A;  2PNS A;  5CHT A;  4NV7 A;  3LXS A;  1YVB A;  2AVW A;  4KLB A;  1F29 A;  3P5V A;  4YV8 A;  1PBH A;  2DCA A;  2B1N A;  3N4C A;  2YJC A;  1AYW A;  2DCD A;  4OEM A;  3MHS A;  1THE A;  1ATK A;  2F1G A;  2FRA A;  4I05 A;  2AYN A;  1TL9 A;  1EWL A;  1GEC E;  5EF4 A;  3P5W A;  3PBH A;  2BSZ A;  3N3G A;  2C0Y A;  1QXP A;  2DZY A;  2DZZ A;  2E00 A;  1AU3 A;  2YJB A;  2XU5 A;  3BC3 A;  5CHV A;  1PXV A;  4FK5 A;  1ITO A;  4XR7 A;  1MDW A;  2HXZ A;  4BPV A;  2E01 A;  3WXF A;  2YJ9 A;  3QT4 A;  1KFX L;  4MZO A;  2G8E A;  1DEU A;  2DJG B;  3CH3 X;  1M6D A;  2NQG A;  1GLO A;  1Q6K A;  3F5V A;  4X6J A;  3P5U A;  4DMX A;  3O1G A;  1NB3 A;  2AIM A;  3LFY A;  3OF9 A;  3USV A;  1AU2 A;  1CS8 A;  1MEG A;  2G7Y A;  1BY8 A;  1Y08 A;  1NQC A;  1STF E;  4I07 A;  3H8B A;  4CZW A;  5PAD A;  5EGW A;  4QH6 A;  2PRE A;  3S3R A;  1U9X A;  4P6E A;  1CVZ A;  1W6F A;  3IV2 A;  1AIM A;  2AUX A;  1POP A;  3OVX A;  3KKU A;  3U8E A;  1CB5 A;  4PP2 E;  4W5B A;  1NB5 A;  1AYU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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