2H7JA

Crystal structure of cathepsin s in complex with a nonpeptidic inhibitor.
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
218
structure length
218
Chain Sequence
ILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin S
total genus 70
structure length 218
sequence length 218
chains with identical sequence B
ec nomenclature ec 3.4.22.27: Cathepsin S.
pdb deposition date 2006-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2h7jA00
1KHPA 4BPVA 2B1NA 2E03A 3F5VA 1F2BA 1PADA 2E01A 1NB3A 3S3QA 4PADA 1MEMA 3P5WA 3B79A 3QT4A 3TNXA 1PPDA 5EF4A 3P5XA 1AYUA 3IOQA 2DC6A 1AYVA 3PDFA 3HWNA 4YVAA 1TLOA 3BOWA 3QJ3A 5FPWA 2JQFR 3MORA 2R9NA 4YYSA 1CS8A 1QXPA 1PPPA 1ITOA 3HHIA 1NPZA 3H7DA 5JA7A 3KW9A 3LXSA 4N79A 3K24A 2NQGA 1CVZA 1ME3A 2DZYA 2F7DA 4MSXA 4W5CA 4CDDB 2Y6EA 1YVBA 3PW3A 4QRVA 3WXFA 2FRQA 4X6JA 3H89A 3H8CA 1NQCA 4G54A 2ATOA 1PPNA 1PXVA 1AYWA 2NQDB 2P0RA 2XU3A 1PPOA 1MHWA 3O1GA 2DJGB 1SP4B 3OVZA 1U9WA 4BQVA 4AXLA 1F2AA 2DCBA 3I06A 1YK8A 2HD5A 1PE6A 1KXRA 1STFE 2GHUA 3N4CA 1GMYA 1VSNA 2JQGR 1SNKA 4FIPA 1NL6A 1F29A 4I04A 2DC7A 2IBIA 2NQIA 2NQAA 4W5BA 1EF7A 1KFXL 2G6DA 1TU6A 4OELA 1U9VA 2P86A 4PI3A 1U5IA 3D6SA 7PCKA 1POPA 3N3GA 3OF9A 2DCCA 1NLJA 2AUXA 2ACTA 2OULA 2G7YA 4BSQA 9PAPA 5CVOB 2G8JA 2DCAA 3AI8A 3NHEA 1KHQA 2XU1A 1ICFA 1ZIVA 2PREA 5CVMA 3IV2A 2PBHA 4QRXA 2AYOA 4ZUXU 1CQDA 2FO5A 1AU0A 3CBJA 1QOLA 1GECE 3HHAA 2FUDA 2O6XA 1YT7A 1BP4A 2F1GA 2ARYA 1YALA 5PADA 1U9QX 2GFOA 3USVA 4CDFB 3QSDA 4FJCA 4DMYA 3IEJA 2YJCA 4HWYA 3MHHA 2AU1A 2FQ9A 1GCBA 1X9YA 2E00A 2PADA 2Y5BA 5A24A 1GLOA 1TL9A 2XU4A 4BS5A 4QH6A 6PADA 2HH5A 3K9MA 3OF8A 2HHNA 4X6HA 4FK5A 1MDWA 4P6EA 3OVXA 5EGWA 2C0YA 3BCNA 2AYNA 3ZUAA 2R9OA 1PBHA 4PP1A 1EWLA 4QBBA 5JH3A 3HD3A 4MZOA 1QMYA 2CIOA 1K3BB 4I05A 2B1MA 2YJ9A 2YJ8A 4K7CA 1M6DA 1Q6KA 2PNSA 3V6EA 3OISA 1QDQA 5CVNB 4RY2A 1KFUL 3MTNA 1BY8A 3RVXA 3N3KA 1ZCMA 2OP3A 1XKGA 1ME4A 3KSEA 2VHSA 2DC9A 2AS8A 1CTEA 1MS6A 2FT2A 4X6IA 1CSBB 2DCDA 4MZSA 3DF0A 2G8EA 3K8UA 4CZWA 2VHFA 2DC8A 3IHPA 3C9EA 3P5VA 2R9FA 1FH0A 3CH3X 3RVVA 3P5UA 3IMAA 3PNRA 4WA6A 2AIMA 1ATKA 2IPPB 1IWDA 4YV8A 1MIRA 4CDCB 1YK7A 3IUTA 3H6SA 3KWBX 4XR7A 4CDEB 2WBFX 4DMXA 1S4VA 3M99A 3MHSA 3BPFA 2R6NA 5K16A 1CJLA 1BQIA 1AECA 3CH2X 1CV8A 2AUZA 2YJBA 2DJFB 4PP2E 1AU2A 3H8BA 3I3TA 4Q8GA 3BPMA 3GCBA 4KLBA 1CPJA 3O0UA 3S3RA 2H7JA 5F02A 1AIMA 3KWZA 1AU3A 4I07A 1PCIA 4AXMA 5J94A 1Y4HA 1BGOA 3ERVA 1EWOA 1EWMA 2DZZA 1DF0A 4BS6A 3LFYA 5CHTA 3U8EA 1HUCB 4YYQA 2CB5A 4N8WA 2FYEA 2BDZA 3CBKA 2HXZA 1O0EA 4N4ZA 2AVWA 2FRAA 2E02A 4YYUA 4QRGA 1DEUA 8PCHA 2P7UA 1THEA 4XUIA 2BDLA 4YYVA 1MEGA 3KKUA 1VJVA 3WXGA 1CB5A 4Q8HA 3BC3A 1JQPA 1U9XA 1A6RA 2YJ2A 3KX1A 2OZ2A 3F75A 3BWKA 2FTDA 3E1ZB 1Y08A 1EWPA 4OEMA 2R9CA 5CHVA 4W4UA 1AU4A 4YYRA 1NB5A 3KFQA 3WXEA 2XU5A 1PIPA 3RVWA 4P6GA 4YYWA 3V6CA 1F2CA 3PBHA 2R9MA
chains in the Genus database with same CATH superfamily
1KHPA 4BPVA 2B1NA 2E03A 3F5VA 1F2BA 1PADA 2E01A 4RNAA 1NB3A 3S3QA 4PADA 1MEMA 3P5WA 3B79A 3QT4A 3TNXA 1PPDA 5KO3A 5EF4A 1PVJA 3P5XA 1AYUA 3IOQA 2DC6A 1AYVA 3PDFA 3HWNA 4YVAA 1TLOA 3BOWA 3QJ3A 5FPWA 2JQFR 3MORA 2DOSA 2R9NA 4YYSA 1CS8A 1QXPA 1PPPA 1ITOA 3PSEA 4WURA 3HHIA 1NPZA 3H7DA 5JA7A 3BY4A 3KW9A 3LXSA 4N79A 3K24A 5EZSA 4BOUA 2NQGA 1CVZA 1ME3A 2DZYA 2FE8A 2F7DA 3TRKA 4MSXA 4W5CA 4CDDB 2Y6EA 1YVBA 3PW3A 4QRVA 2UZJA 3WXFA 4IUMA 2FRQA 4X6JA 3W30A 3H89A 3H8CA 1NQCA 4G54A 2ATOA 4D8IA 4D8BA 1PPNA 1PXVA 1AYWA 2NQDB 2P0RA 3BBAA 4REZA 2XU3A 1PPOA 5E6JA 1MHWA 3O1GA 2DJGB 1SP4B 3OVZA 1U9WA 4BQVA 4AXLA 3OQCA 1F2AA 3ZNHA 2DCBA 3I06A 1YK8A 2HD5A 1PE6A 1KXRA 1STFE 2GHUA 3N4CA 1GMYA 1VSNA 2JQGR 1SNKA 4FIPA 1NL6A 1F29A 3MJ5A 4I04A 2DC7A 2IBIA 2NQIA 2NQAA 4W5BA 1EF7A 1KFXL 2G6DA 1TU6A 4BOZA 4OELA 1U9VA 2P86A 4PI3A 4PT5A 1U5IA 2J7QC 3D6SA 7PCKA 1POPA 3N3GA 3OF9A 2DCCA 1NLJA 2AUXA 2ACTA 2OULA 2G7YA 4BSQA 9PAPA 5CVOB 2G8JA 2DCAA 2BTWB 3AI8A 3NHEA 1KHQA 2J7QA 2XU1A 2BU3A 1ICFA 1ZIVA 2PREA 5CVMA 3IV2A 2PBHA 4QRXA 2AYOA 4HXDB 3PT2A 4ZUXU 4MI7A 3PRPA 1CQDA 3PHWA 2FO5A 1AU0A 3CBJA 1QOLA 1GECE 3HHAA 2FUDA 2O6XA 1YT7A 1BP4A 2F1GA 2ARYA 1YALA 4BOPA 5PADA 4BOQA 1U9QX 2GFOA 3USVA 4CDFB 3QSDA 4FJCA 4DMYA 3IEJA 4R3DA 2YJCA 4OVZA 4D8EA 4HWYA 3MHHA 2AU1A 2FQ9A 1GCBA 1X9YA 2E00A 2PADA 2Y5BA 1UKFA 3W31A 5A24A 1GLOA 1TL9A 2XU4A 4BS5A 4QH6A 4MM3B 4A5UA 6PADA 3RNVA 2HH5A 3E9SA 4RF1A 3K9MA 3OF8A 2HHNA 4RF0A 4X6HA 4FK5A 1MDWA 4P6EA 3OVXA 5EGWA 2C0YA 3BCNA 2AYNA 3ZUAA 2R9OA 1PBHA 4PP1A 1EWLA 4RKXA 4QBBA 1YZBA 5JH3A 3HD3A 4MZOA 1QMYA 2CIOA 1K3BB 4I05A 2B1MA 2YJ9A 2JTCA 2YJ8A 4K7CA 1M6DA 1Q6KA 2PNSA 3PRMA 3V6EA 3OISA 1QDQA 5CVNB 3B21A 4RY2A 3MP2A 1KFUL 3MTNA 1BY8A 3RVXA 4XZXA 4OVZB 3N3KA 1ZCMA 2OP3A 1XKGA 1ME4A 3KSEA 2VHSA 3MTVA 2DC9A 2AS8A 1CTEA 1MS6A 2FT2A 4X6IA 1CSBB 2DCDA 4MZSA 3DF0A 2G8EA 2JRIA 3IFUA 3K8UA 4CZWA 2VHFA 2DC8A 3IHPA 3C9EA 3P5VA 2R9FA 1FH0A 3CH3X 3RVVA 3P5UA 3IMAA 3PNRA 4M0WA 4WA6A 2AIMA 1ATKA 2IPPB 1IWDA 4YV8A 1MIRA 4CDCB 1YK7A 3IUTA 3H6SA 3KWBX 4GUAA 4XR7A 4CDEB 2WBFX 4DMXA 3O65A 1S4VA 4OW0A 3M99A 4IP3A 3MHSA 3BPFA 2R6NA 5K16A 2Z84A 3C0RA 1CJLA 1BQIA 1AECA 4BOSA 3CH2X 1CV8A 2AUZA 2YJBA 2DJFB 4PP2E 1AU2A 3H8BA 4P16A 3I3TA 4Q8GA 3BPMA 3GCBA 4KLBA 1CPJA 3O0UA 3S3RA 5EZQA 2H7JA 3BB7A 5F02A 1AIMA 3KWZA 1AU3A 4I07A 1PCIA 4AXMA 2HWKA 5J94A 1Y4HA 1BGOA 3ERVA 1EWOA 1EWMA 2DZZA 1DKIA 1DF0A 4BS6A 3PHUA 3LFYA 5CHTA 3U8EA 1HUCB 4YYQA 2CB5A 4N8WA 2FYEA 2BDZA 3CBKA 2HXZA 2AGAA 3PHXA 2BTWA 1O0EA 4N4ZA 2AVWA 2FRAA 2E02A 4YYUA 4QRGA 1DEUA 4ZTBA 8PCHA 2P7UA 1THEA 4XUIA 2BDLA 4YYVA 1MEGA 3KKUA 1VJVA 3WXGA 1CB5A 4Q8HA 3BC3A 1JQPA 1U9XA 1A6RA 2YJ2A 3KX1A 2OZ2A 3F75A 3TMPA 3BWKA 2FTDA 3E1ZB 1Y08A 5JZEA 1EWPA 4OEMA 2R9CA 5CHVA 4W4UA 1AU4A 4YYRA 1NB5A 3KFQA 3WXEA 2XU5A 1PIPA 3RVWA 4P6GA 4YYWA 3V6CA 1F2CA 3PBHA 2R9MA
chains in the Genus database with same CATH topology
1KHPA 4BPVA 2B1NA 2E03A 3F5VA 1F2BA 1PADA 2E01A 1NB3A 3S3QA 4PADA 1MEMA 3P5WA 3B79A 3QT4A 3TNXA 1PPDA 5EF4A 3P5XA 1AYUA 3IOQA 2DC6A 1AYVA 3PDFA 3HWNA 4YVAA 1TLOA 3BOWA 3QJ3A 5FPWA 2JQFR 3MORA 2R9NA 4YYSA 1CS8A 1QXPA 1PPPA 1ITOA 4NV7A 3HHIA 1NPZA 3H7DA 5JA7A 3KW9A 3LXSA 4N79A 3K24A 2NQGA 1CVZA 1ME3A 2DZYA 2F7DA 4MSXA 4W5CA 4CDDB 2Y6EA 2VFCA 1YVBA 3PW3A 4QRVA 3WXFA 2FRQA 4X6JA 3H89A 3H8CA 1NQCA 4G54A 2ATOA 1PPNA 1PXVA 1AYWA 2NQDB 2P0RA 2XU3A 1PPOA 1MHWA 3O1GA 2DJGB 1SP4B 3OVZA 1U9WA 4BQVA 4AXLA 1F2AA 2DCBA 3I06A 1YK8A 2HD5A 1PE6A 1KXRA 1STFE 2GHUA 3N4CA 1GMYA 1VSNA 2JQGR 1SNKA 4FIPA 1NL6A 1F29A 4I04A 2DC7A 2IBIA 2NQIA 2NQAA 4W5BA 1EF7A 1KFXL 2G6DA 4GUZA 1TU6A 4OELA 1U9VA 2P86A 4PI3A 1U5IA 3D6SA 7PCKA 1POPA 3N3GA 3OF9A 2DCCA 1NLJA 2AUXA 2ACTA 2OULA 2G7YA 4BSQA 9PAPA 5CVOB 2G8JA 2DCAA 3AI8A 3NHEA 1KHQA 2XU1A 1ICFA 1ZIVA 2PREA 3LTWA 5CVMA 3IV2A 2PBHA 4QRXA 2AYOA 4ZUXU 1CQDA 2FO5A 1AU0A 3CBJA 1QOLA 1GECE 3HHAA 2FUDA 2O6XA 1YT7A 1BP4A 2F1GA 2BSZA 1GX3A 2ARYA 1YALA 5PADA 1W4TA 1W5RA 1U9QX 2GFOA 3USVA 4CDFB 3QSDA 4FJCA 4DMYA 3IEJA 2YJCA 4HWYA 3MHHA 2AU1A 2VFBA 2FQ9A 1GCBA 1X9YA 2E00A 2PADA 2Y5BA 5A24A 1GLOA 1TL9A 2XU4A 4BS5A 4QH6A 6PADA 2HH5A 3K9MA 3OF8A 2HHNA 4X6HA 4FK5A 1MDWA 4P6EA 3OVXA 5EGWA 2C0YA 3BCNA 2AYNA 3ZUAA 2R9OA 1PBHA 4PP1A 1EWLA 4QBBA 5JH3A 3HD3A 1E2TA 4MZOA 1QMYA 2CIOA 1K3BB 4I05A 2B1MA 2YJ9A 2YJ8A 4K7CA 1M6DA 1Q6KA 2PNSA 3V6EA 3OISA 1QDQA 5CVNB 4RY2A 1KFUL 3MTNA 1BY8A 3RVXA 4NV8A 3N3KA 3D9WA 1ZCMA 2OP3A 1XKGA 4B55A 1ME4A 3KSEA 2VHSA 2DC9A 2AS8A 1CTEA 1MS6A 2FT2A 4C5PA 4X6IA 1CSBB 2DCDA 4MZSA 3DF0A 2G8EA 3K8UA 4CZWA 2VHFA 4BGFA 2DC8A 3IHPA 3C9EA 3P5VA 2R9FA 1FH0A 3CH3X 3RVVA 3P5UA 3IMAA 3PNRA 4WA6A 2AIMA 1ATKA 2IPPB 1IWDA 4YV8A 1MIRA 4CDCB 1YK7A 3IUTA 3H6SA 3KWBX 4XR7A 4CDEB 2WBFX 4DMXA 1S4VA 3M99A 3MHSA 3BPFA 2R6NA 5K16A 1CJLA 1BQIA 1AECA 3CH2X 1CV8A 2AUZA 2YJBA 2DJFB 4PP2E 1W6FA 1AU2A 3H8BA 3I3TA 4Q8GA 3BPMA 3GCBA 4KLBA 1CPJA 3O0UA 3S3RA 2H7JA 5F02A 1AIMA 3KWZA 1AU3A 4I07A 1PCIA 4AXMA 5J94A 1Y4HA 1BGOA 3ERVA 1EWOA 1EWMA 2DZZA 1DF0A 4BS6A 3LFYA 5CHTA 3U8EA 1HUCB 4YYQA 2CB5A 4N8WA 2FYEA 2BDZA 3CBKA 2HXZA 1O0EA 4N4ZA 2AVWA 2FRAA 2E02A 4YYUA 4QRGA 1DEUA 8PCHA 2P7UA 1THEA 4XUIA 2BDLA 4YYVA 1MEGA 3KKUA 1VJVA 3WXGA 1CB5A 4Q8HA 3BC3A 1JQPA 1U9XA 1A6RA 2YJ2A 3KX1A 2OZ2A 3F75A 3BWKA 2FTDA 3E1ZB 1Y08A 1EWPA 4OEMA 2R9CA 5CHVA 4W4UA 1AU4A 4YYRA 1NB5A 3KFQA 3WXEA 2XU5A 1PIPA 3RVWA 4P6GA 4YYWA 3V6CA 1F2CA 3PBHA 2R9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KHP A;  4BPV A;  2B1N A;  2E03 A;  3F5V A;  1F2B A;  1PAD A;  2E01 A;  1NB3 A;  3S3Q A;  4PAD A;  1MEM A;  3P5W A;  3B79 A;  3QT4 A;  3TNX A;  1PPD A;  5EF4 A;  3P5X A;  1AYU A;  3IOQ A;  2DC6 A;  1AYV A;  3PDF A;  3HWN A;  4YVA A;  1TLO A;  3BOW A;  3QJ3 A;  5FPW A;  2JQF R;  3MOR A;  2R9N A;  4YYS A;  1CS8 A;  1QXP A;  1PPP A;  1ITO A;  3HHI A;  1NPZ A;  3H7D A;  5JA7 A;  3KW9 A;  3LXS A;  4N79 A;  3K24 A;  2NQG A;  1CVZ A;  1ME3 A;  2DZY A;  2F7D A;  4MSX A;  4W5C A;  4CDD B;  2Y6E A;  1YVB A;  3PW3 A;  4QRV A;  3WXF A;  2FRQ A;  4X6J A;  3H89 A;  3H8C A;  1NQC A;  4G54 A;  2ATO A;  1PPN A;  1PXV A;  1AYW A;  2NQD B;  2P0R A;  2XU3 A;  1PPO A;  1MHW A;  3O1G A;  2DJG B;  1SP4 B;  3OVZ A;  1U9W A;  4BQV A;  4AXL A;  1F2A A;  2DCB A;  3I06 A;  1YK8 A;  2HD5 A;  1PE6 A;  1KXR A;  1STF E;  2GHU A;  3N4C A;  1GMY A;  1VSN A;  2JQG R;  1SNK A;  4FIP A;  1NL6 A;  1F29 A;  4I04 A;  2DC7 A;  2IBI A;  2NQI A;  2NQA A;  4W5B A;  1EF7 A;  1KFX L;  2G6D A;  1TU6 A;  4OEL A;  1U9V A;  2P86 A;  4PI3 A;  1U5I A;  3D6S A;  7PCK A;  1POP A;  3N3G A;  3OF9 A;  2DCC A;  1NLJ A;  2AUX A;  2ACT A;  2OUL A;  2G7Y A;  4BSQ A;  9PAP A;  5CVO B;  2G8J A;  2DCA A;  3AI8 A;  3NHE A;  1KHQ A;  2XU1 A;  1ICF A;  1ZIV A;  2PRE A;  5CVM A;  3IV2 A;  2PBH A;  4QRX A;  2AYO A;  4ZUX U;  1CQD A;  2FO5 A;  1AU0 A;  3CBJ A;  1QOL A;  1GEC E;  3HHA A;  2FUD A;  2O6X A;  1YT7 A;  1BP4 A;  2F1G A;  2ARY A;  1YAL A;  5PAD A;  1U9Q X;  2GFO A;  3USV A;  4CDF B;  3QSD A;  4FJC A;  4DMY A;  3IEJ A;  2YJC A;  4HWY A;  3MHH A;  2AU1 A;  2FQ9 A;  1GCB A;  1X9Y A;  2E00 A;  2PAD A;  2Y5B A;  5A24 A;  1GLO A;  1TL9 A;  2XU4 A;  4BS5 A;  4QH6 A;  6PAD A;  2HH5 A;  3K9M A;  3OF8 A;  2HHN A;  4X6H A;  4FK5 A;  1MDW A;  4P6E A;  3OVX A;  5EGW A;  2C0Y A;  3BCN A;  2AYN A;  3ZUA A;  2R9O A;  1PBH A;  4PP1 A;  1EWL A;  4QBB A;  5JH3 A;  3HD3 A;  4MZO A;  1QMY A;  2CIO A;  1K3B B;  4I05 A;  2B1M A;  2YJ9 A;  2YJ8 A;  4K7C A;  1M6D A;  1Q6K A;  2PNS A;  3V6E A;  3OIS A;  1QDQ A;  5CVN B;  4RY2 A;  1KFU L;  3MTN A;  1BY8 A;  3RVX A;  3N3K A;  1ZCM A;  2OP3 A;  1XKG A;  1ME4 A;  3KSE A;  2VHS A;  2DC9 A;  2AS8 A;  1CTE A;  1MS6 A;  2FT2 A;  4X6I A;  1CSB B;  2DCD A;  4MZS A;  3DF0 A;  2G8E A;  3K8U A;  4CZW A;  2VHF A;  2DC8 A;  3IHP A;  3C9E A;  3P5V A;  2R9F A;  1FH0 A;  3CH3 X;  3RVV A;  3P5U A;  3IMA A;  3PNR A;  4WA6 A;  2AIM A;  1ATK A;  2IPP B;  1IWD A;  4YV8 A;  1MIR A;  4CDC B;  1YK7 A;  3IUT A;  3H6S A;  3KWB X;  4XR7 A;  4CDE B;  2WBF X;  4DMX A;  1S4V A;  3M99 A;  3MHS A;  3BPF A;  2R6N A;  5K16 A;  1CJL A;  1BQI A;  1AEC A;  3CH2 X;  1CV8 A;  2AUZ A;  2YJB A;  2DJF B;  4PP2 E;  1AU2 A;  3H8B A;  3I3T A;  4Q8G A;  3BPM A;  3GCB A;  4KLB A;  1CPJ A;  3O0U A;  3S3R A;  2H7J A;  5F02 A;  1AIM A;  3KWZ A;  1AU3 A;  4I07 A;  1PCI A;  4AXM A;  5J94 A;  1Y4H A;  1BGO A;  3ERV A;  1EWO A;  1EWM A;  2DZZ A;  1DF0 A;  4BS6 A;  3LFY A;  5CHT A;  3U8E A;  1HUC B;  4YYQ A;  2CB5 A;  4N8W A;  2FYE A;  2BDZ A;  3CBK A;  2HXZ A;  1O0E A;  4N4Z A;  2AVW A;  2FRA A;  2E02 A;  4YYU A;  4QRG A;  1DEU A;  8PCH A;  2P7U A;  1THE A;  4XUI A;  2BDL A;  4YYV A;  1MEG A;  3KKU A;  1VJV A;  3WXG A;  1CB5 A;  4Q8H A;  3BC3 A;  1JQP A;  1U9X A;  1A6R A;  2YJ2 A;  3KX1 A;  2OZ2 A;  3F75 A;  3BWK A;  2FTD A;  3E1Z B;  1Y08 A;  1EWP A;  4OEM A;  2R9C A;  5CHV A;  4W4U A;  1AU4 A;  4YYR A;  1NB5 A;  3KFQ A;  3WXE A;  2XU5 A;  1PIP A;  3RVW A;  4P6G A;  4YYW A;  3V6C A;  1F2C A;  3PBH A;  2R9M A; 
#chains in the Genus database with same CATH topology
 1KHP A;  4BPV A;  2B1N A;  2E03 A;  3F5V A;  1F2B A;  1PAD A;  2E01 A;  4RNA A;  1NB3 A;  3S3Q A;  4PAD A;  1MEM A;  3P5W A;  3B79 A;  3QT4 A;  3TNX A;  1PPD A;  5KO3 A;  5EF4 A;  1PVJ A;  3P5X A;  1AYU A;  3IOQ A;  2DC6 A;  1AYV A;  3PDF A;  3HWN A;  4YVA A;  1TLO A;  3BOW A;  3QJ3 A;  5FPW A;  2JQF R;  3MOR A;  2DOS A;  2R9N A;  4YYS A;  1CS8 A;  1QXP A;  1PPP A;  1ITO A;  3PSE A;  4WUR A;  3HHI A;  1NPZ A;  3H7D A;  5JA7 A;  3BY4 A;  3KW9 A;  3LXS A;  4N79 A;  3K24 A;  5EZS A;  4BOU A;  2NQG A;  1CVZ A;  1ME3 A;  2DZY A;  2FE8 A;  2F7D A;  3TRK A;  4MSX A;  4W5C A;  4CDD B;  2Y6E A;  1YVB A;  3PW3 A;  4QRV A;  2UZJ A;  3WXF A;  4IUM A;  2FRQ A;  4X6J A;  3W30 A;  3H89 A;  3H8C A;  1NQC A;  4G54 A;  2ATO A;  4D8I A;  4D8B A;  1PPN A;  1PXV A;  1AYW A;  2NQD B;  2P0R A;  3BBA A;  4REZ A;  2XU3 A;  1PPO A;  5E6J A;  1MHW A;  3O1G A;  2DJG B;  1SP4 B;  3OVZ A;  1U9W A;  4BQV A;  4AXL A;  3OQC A;  1F2A A;  3ZNH A;  2DCB A;  3I06 A;  1YK8 A;  2HD5 A;  1PE6 A;  1KXR A;  1STF E;  2GHU A;  3N4C A;  1GMY A;  1VSN A;  2JQG R;  1SNK A;  4FIP A;  1NL6 A;  1F29 A;  3MJ5 A;  4I04 A;  2DC7 A;  2IBI A;  2NQI A;  2NQA A;  4W5B A;  1EF7 A;  1KFX L;  2G6D A;  1TU6 A;  4BOZ A;  4OEL A;  1U9V A;  2P86 A;  4PI3 A;  4PT5 A;  1U5I A;  2J7Q C;  3D6S A;  7PCK A;  1POP A;  3N3G A;  3OF9 A;  2DCC A;  1NLJ A;  2AUX A;  2ACT A;  2OUL A;  2G7Y A;  4BSQ A;  9PAP A;  5CVO B;  2G8J A;  2DCA A;  2BTW B;  3AI8 A;  3NHE A;  1KHQ A;  2J7Q A;  2XU1 A;  2BU3 A;  1ICF A;  1ZIV A;  2PRE A;  5CVM A;  3IV2 A;  2PBH A;  4QRX A;  2AYO A;  4HXD B;  3PT2 A;  4ZUX U;  4MI7 A;  3PRP A;  1CQD A;  3PHW A;  2FO5 A;  1AU0 A;  3CBJ A;  1QOL A;  1GEC E;  3HHA A;  2FUD A;  2O6X A;  1YT7 A;  1BP4 A;  2F1G A;  2ARY A;  1YAL A;  4BOP A;  5PAD A;  4BOQ A;  1U9Q X;  2GFO A;  3USV A;  4CDF B;  3QSD A;  4FJC A;  4DMY A;  3IEJ A;  4R3D A;  2YJC A;  4OVZ A;  4D8E A;  4HWY A;  3MHH A;  2AU1 A;  2FQ9 A;  1GCB A;  1X9Y A;  2E00 A;  2PAD A;  2Y5B A;  1UKF A;  3W31 A;  5A24 A;  1GLO A;  1TL9 A;  2XU4 A;  4BS5 A;  4QH6 A;  4MM3 B;  4A5U A;  6PAD A;  3RNV A;  2HH5 A;  3E9S A;  4RF1 A;  3K9M A;  3OF8 A;  2HHN A;  4RF0 A;  4X6H A;  4FK5 A;  1MDW A;  4P6E A;  3OVX A;  5EGW A;  2C0Y A;  3BCN A;  2AYN A;  3ZUA A;  2R9O A;  1PBH A;  4PP1 A;  1EWL A;  4RKX A;  4QBB A;  1YZB A;  5JH3 A;  3HD3 A;  4MZO A;  1QMY A;  2CIO A;  1K3B B;  4I05 A;  2B1M A;  2YJ9 A;  2JTC A;  2YJ8 A;  4K7C A;  1M6D A;  1Q6K A;  2PNS A;  3PRM A;  3V6E A;  3OIS A;  1QDQ A;  5CVN B;  3B21 A;  4RY2 A;  3MP2 A;  1KFU L;  3MTN A;  1BY8 A;  3RVX A;  4XZX A;  4OVZ B;  3N3K A;  1ZCM A;  2OP3 A;  1XKG A;  1ME4 A;  3KSE A;  2VHS A;  3MTV A;  2DC9 A;  2AS8 A;  1CTE A;  1MS6 A;  2FT2 A;  4X6I A;  1CSB B;  2DCD A;  4MZS A;  3DF0 A;  2G8E A;  2JRI A;  3IFU A;  3K8U A;  4CZW A;  2VHF A;  2DC8 A;  3IHP A;  3C9E A;  3P5V A;  2R9F A;  1FH0 A;  3CH3 X;  3RVV A;  3P5U A;  3IMA A;  3PNR A;  4M0W A;  4WA6 A;  2AIM A;  1ATK A;  2IPP B;  1IWD A;  4YV8 A;  1MIR A;  4CDC B;  1YK7 A;  3IUT A;  3H6S A;  3KWB X;  4GUA A;  4XR7 A;  4CDE B;  2WBF X;  4DMX A;  3O65 A;  1S4V A;  4OW0 A;  3M99 A;  4IP3 A;  3MHS A;  3BPF A;  2R6N A;  5K16 A;  2Z84 A;  3C0R A;  1CJL A;  1BQI A;  1AEC A;  4BOS A;  3CH2 X;  1CV8 A;  2AUZ A;  2YJB A;  2DJF B;  4PP2 E;  1AU2 A;  3H8B A;  4P16 A;  3I3T A;  4Q8G A;  3BPM A;  3GCB A;  4KLB A;  1CPJ A;  3O0U A;  3S3R A;  5EZQ A;  2H7J A;  3BB7 A;  5F02 A;  1AIM A;  3KWZ A;  1AU3 A;  4I07 A;  1PCI A;  4AXM A;  2HWK A;  5J94 A;  1Y4H A;  1BGO A;  3ERV A;  1EWO A;  1EWM A;  2DZZ A;  1DKI A;  1DF0 A;  4BS6 A;  3PHU A;  3LFY A;  5CHT A;  3U8E A;  1HUC B;  4YYQ A;  2CB5 A;  4N8W A;  2FYE A;  2BDZ A;  3CBK A;  2HXZ A;  2AGA A;  3PHX A;  2BTW A;  1O0E A;  4N4Z A;  2AVW A;  2FRA A;  2E02 A;  4YYU A;  4QRG A;  1DEU A;  4ZTB A;  8PCH A;  2P7U A;  1THE A;  4XUI A;  2BDL A;  4YYV A;  1MEG A;  3KKU A;  1VJV A;  3WXG A;  1CB5 A;  4Q8H A;  3BC3 A;  1JQP A;  1U9X A;  1A6R A;  2YJ2 A;  3KX1 A;  2OZ2 A;  3F75 A;  3TMP A;  3BWK A;  2FTD A;  3E1Z B;  1Y08 A;  5JZE A;  1EWP A;  4OEM A;  2R9C A;  5CHV A;  4W4U A;  1AU4 A;  4YYR A;  1NB5 A;  3KFQ A;  3WXE A;  2XU5 A;  1PIP A;  3RVW A;  4P6G A;  4YYW A;  3V6C A;  1F2C A;  3PBH A;  2R9M A; 
#chains in the Genus database with same CATH homology
 1KHP A;  4BPV A;  2B1N A;  2E03 A;  3F5V A;  1F2B A;  1PAD A;  2E01 A;  1NB3 A;  3S3Q A;  4PAD A;  1MEM A;  3P5W A;  3B79 A;  3QT4 A;  3TNX A;  1PPD A;  5EF4 A;  3P5X A;  1AYU A;  3IOQ A;  2DC6 A;  1AYV A;  3PDF A;  3HWN A;  4YVA A;  1TLO A;  3BOW A;  3QJ3 A;  5FPW A;  2JQF R;  3MOR A;  2R9N A;  4YYS A;  1CS8 A;  1QXP A;  1PPP A;  1ITO A;  4NV7 A;  3HHI A;  1NPZ A;  3H7D A;  5JA7 A;  3KW9 A;  3LXS A;  4N79 A;  3K24 A;  2NQG A;  1CVZ A;  1ME3 A;  2DZY A;  2F7D A;  4MSX A;  4W5C A;  4CDD B;  2Y6E A;  2VFC A;  1YVB A;  3PW3 A;  4QRV A;  3WXF A;  2FRQ A;  4X6J A;  3H89 A;  3H8C A;  1NQC A;  4G54 A;  2ATO A;  1PPN A;  1PXV A;  1AYW A;  2NQD B;  2P0R A;  2XU3 A;  1PPO A;  1MHW A;  3O1G A;  2DJG B;  1SP4 B;  3OVZ A;  1U9W A;  4BQV A;  4AXL A;  1F2A A;  2DCB A;  3I06 A;  1YK8 A;  2HD5 A;  1PE6 A;  1KXR A;  1STF E;  2GHU A;  3N4C A;  1GMY A;  1VSN A;  2JQG R;  1SNK A;  4FIP A;  1NL6 A;  1F29 A;  4I04 A;  2DC7 A;  2IBI A;  2NQI A;  2NQA A;  4W5B A;  1EF7 A;  1KFX L;  2G6D A;  4GUZ A;  1TU6 A;  4OEL A;  1U9V A;  2P86 A;  4PI3 A;  1U5I A;  3D6S A;  7PCK A;  1POP A;  3N3G A;  3OF9 A;  2DCC A;  1NLJ A;  2AUX A;  2ACT A;  2OUL A;  2G7Y A;  4BSQ A;  9PAP A;  5CVO B;  2G8J A;  2DCA A;  3AI8 A;  3NHE A;  1KHQ A;  2XU1 A;  1ICF A;  1ZIV A;  2PRE A;  3LTW A;  5CVM A;  3IV2 A;  2PBH A;  4QRX A;  2AYO A;  4ZUX U;  1CQD A;  2FO5 A;  1AU0 A;  3CBJ A;  1QOL A;  1GEC E;  3HHA A;  2FUD A;  2O6X A;  1YT7 A;  1BP4 A;  2F1G A;  2BSZ A;  1GX3 A;  2ARY A;  1YAL A;  5PAD A;  1W4T A;  1W5R A;  1U9Q X;  2GFO A;  3USV A;  4CDF B;  3QSD A;  4FJC A;  4DMY A;  3IEJ A;  2YJC A;  4HWY A;  3MHH A;  2AU1 A;  2VFB A;  2FQ9 A;  1GCB A;  1X9Y A;  2E00 A;  2PAD A;  2Y5B A;  5A24 A;  1GLO A;  1TL9 A;  2XU4 A;  4BS5 A;  4QH6 A;  6PAD A;  2HH5 A;  3K9M A;  3OF8 A;  2HHN A;  4X6H A;  4FK5 A;  1MDW A;  4P6E A;  3OVX A;  5EGW A;  2C0Y A;  3BCN A;  2AYN A;  3ZUA A;  2R9O A;  1PBH A;  4PP1 A;  1EWL A;  4QBB A;  5JH3 A;  3HD3 A;  1E2T A;  4MZO A;  1QMY A;  2CIO A;  1K3B B;  4I05 A;  2B1M A;  2YJ9 A;  2YJ8 A;  4K7C A;  1M6D A;  1Q6K A;  2PNS A;  3V6E A;  3OIS A;  1QDQ A;  5CVN B;  4RY2 A;  1KFU L;  3MTN A;  1BY8 A;  3RVX A;  4NV8 A;  3N3K A;  3D9W A;  1ZCM A;  2OP3 A;  1XKG A;  4B55 A;  1ME4 A;  3KSE A;  2VHS A;  2DC9 A;  2AS8 A;  1CTE A;  1MS6 A;  2FT2 A;  4C5P A;  4X6I A;  1CSB B;  2DCD A;  4MZS A;  3DF0 A;  2G8E A;  3K8U A;  4CZW A;  2VHF A;  4BGF A;  2DC8 A;  3IHP A;  3C9E A;  3P5V A;  2R9F A;  1FH0 A;  3CH3 X;  3RVV A;  3P5U A;  3IMA A;  3PNR A;  4WA6 A;  2AIM A;  1ATK A;  2IPP B;  1IWD A;  4YV8 A;  1MIR A;  4CDC B;  1YK7 A;  3IUT A;  3H6S A;  3KWB X;  4XR7 A;  4CDE B;  2WBF X;  4DMX A;  1S4V A;  3M99 A;  3MHS A;  3BPF A;  2R6N A;  5K16 A;  1CJL A;  1BQI A;  1AEC A;  3CH2 X;  1CV8 A;  2AUZ A;  2YJB A;  2DJF B;  4PP2 E;  1W6F A;  1AU2 A;  3H8B A;  3I3T A;  4Q8G A;  3BPM A;  3GCB A;  4KLB A;  1CPJ A;  3O0U A;  3S3R A;  2H7J A;  5F02 A;  1AIM A;  3KWZ A;  1AU3 A;  4I07 A;  1PCI A;  4AXM A;  5J94 A;  1Y4H A;  1BGO A;  3ERV A;  1EWO A;  1EWM A;  2DZZ A;  1DF0 A;  4BS6 A;  3LFY A;  5CHT A;  3U8E A;  1HUC B;  4YYQ A;  2CB5 A;  4N8W A;  2FYE A;  2BDZ A;  3CBK A;  2HXZ A;  1O0E A;  4N4Z A;  2AVW A;  2FRA A;  2E02 A;  4YYU A;  4QRG A;  1DEU A;  8PCH A;  2P7U A;  1THE A;  4XUI A;  2BDL A;  4YYV A;  1MEG A;  3KKU A;  1VJV A;  3WXG A;  1CB5 A;  4Q8H A;  3BC3 A;  1JQP A;  1U9X A;  1A6R A;  2YJ2 A;  3KX1 A;  2OZ2 A;  3F75 A;  3BWK A;  2FTD A;  3E1Z B;  1Y08 A;  1EWP A;  4OEM A;  2R9C A;  5CHV A;  4W4U A;  1AU4 A;  4YYR A;  1NB5 A;  3KFQ A;  3WXE A;  2XU5 A;  1PIP A;  3RVW A;  4P6G A;  4YYW A;  3V6C A;  1F2C A;  3PBH A;  2R9M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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