2NQDB

Crystal structure of cysteine protease inhibitor, chagasin, in complex with human cathepsin l
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
221
structure length
221
Chain Sequence
EAPRSVDWREKGYVTPVKNQGQCGSAWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease
pubmed doi rcsb
molecule tags Hydrolase inhibitor/hydrolase
source organism Trypanosoma cruzi
molecule keywords Chagasin
total genus 72
structure length 221
sequence length 221
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2nqdB00
2FRQA 1KFUL 1ITOA 2HHNA 2YJCA 3OVXA 2FTDA 2VHFA 3IMAA 4CDFB 6PADA 4QH6A 1F2BA 2FYEA 2PADA 3WXEA 4FJCA 4XUIA 1PPDA 4X6IA 4AXMA 3BWKA 1CSBB 4YYRA 1EWOA 3E1ZB 1NL6A 1ICFA 1AYWA 2PBHA 2XU4A 4X6HA 5JA7A 5PADA 3OF9A 2XU5A 2ARYA 1M6DA 1XKGA 3WXFA 1STFE 1MDWA 3IHPA 3ERVA 3CBKA 2AYNA 4QBBA 3DF0A 1KFXL 2E03A 2VHSA 2DZYA 3C9EA 1ME4A 5K16A 4N8WA 1AU4A 1Y08A 3PNRA 1KHQA 1VJVA 1YT7A 3O1GA 1CB5A 2YJBA 1THEA 1YALA 2C0YA 3PDFA 2FRAA 2G6DA 1NLJA 1AYUA 1Y4HA 3HD3A 2AIMA 3KKUA 1MHWA 2OP3A 2IBIA 3RVWA 4PP2E 1SP4B 3H7DA 2ATOA 3F5VA 5EGWA 1GCBA 1PXVA 3PW3A 4PP1A 1PADA 2NQAA 4DMXA 2G8EA 2B1NA 4QRGA 4X6JA 1AU2A 2DJFB 1MEGA 3KWBX 2DC6A 1DF0A 1Q6KA 1YK8A 1TL9A 3MTNA 1GMYA 3V6EA 2DZZA 2DC8A 1ZCMA 3S3QA 3KW9A 2AU1A 3CH3X 3IOQA 1F29A 2GHUA 2DCBA 3P5VA 2R9FA 4I07A 1K3BB 5EF4A 1POPA 1BY8A 2HXZA 1SNKA 4HWYA 2CB5A 1QXPA 5CVOB 2PREA 1YVBA 2PNSA 4QRXA 4ZUXU 3IEJA 3H8CA 1CPJA 1GECE 3U8EA 4YYSA 1NB5A 1U9XA 1NQCA 3D6SA 3IUTA 1PBHA 3MHHA 3HHAA 2AUXA 3USVA 3M99A 3BC3A 2YJ9A 4BS5A 2F1GA 4CDCB 4W4UA 4YYQA 1MS6A 2JQGR 3K9MA 1AYVA 2XU3A 2YJ8A 4MZOA 1PE6A 3RVVA 3K8UA 4KLBA 4MSXA 1KHPA 3H8BA 9PAPA 4K7CA 3IV2A 2R9NA 2FT2A 2P86A 1QDQA 1EWPA 3H89A 1QMYA 1U9VA 2AS8A 4YYUA 1ZIVA 2ACTA 1PPNA 2R9OA 1EWMA 2AYOA 2AUZA 3BCNA 4RY2A 1KXRA 2NQGA 3CBJA 3LXSA 4YYVA 3P5UA 2G7YA 3BPFA 4N79A 3BPMA 4MZSA 3CH2X 2DC9A 5A24A 4PI3A 3OVZA 2HH5A 3GCBA 3KSEA 3HWNA 4CDEB 2R6NA 3QJ3A 4Q8GA 1PCIA 4AXLA 1EF7A 1AIMA 3OF8A 2E00A 3AI8A 5CHVA 1F2AA 2E01A 3QSDA 1S4VA 1X9YA 1MIRA 1TLOA 1PIPA 1EWLA 1MEMA 4FIPA 2H7JA 2CIOA 5CHTA 1CQDA 2BDLA 4YVAA 2O6XA 3BOWA 4Q8HA 1CTEA 2G8JA 3KFQA 1QOLA 2F7DA 4BQVA 3B79A 2DC7A 1TU6A 4I05A 3RVXA 4CDDB 2JQFR 1AU3A 1A6RA 1CVZA 1NB3A 1F2CA 2AVWA 1VSNA 2HD5A 1GLOA 1HUCB 5CVMA 3O0UA 4CZWA 1BP4A 1NPZA 2YJ2A 4P6GA 2DCCA 1CV8A 1PPPA 2Y5BA 1BQIA 4WA6A 3I3TA 2P0RA 2GFOA 3PBHA 2DCAA 7PCKA 1FH0A 2NQIA 2E02A 4QRVA 1AU0A 3N3KA 4DMYA 2R9MA 3K24A 3TNXA 3N4CA 4W5BA 4BSQA 3P5WA 3LFYA 5F02A 3WXGA 2DCDA 4OEMA 3V6CA 3S3RA 2FO5A 4I04A 2NQDB 1U9QX 1IWDA 2R9CA 4YV8A 4XR7A 3ZUAA 4YYWA 4OELA 1AECA 4N4ZA 1BGOA 1O0EA 3MORA 5FPWA 2FUDA 1DEUA 3P5XA 2WBFX 8PCHA 4BS6A 1YK7A 2FQ9A 1PPOA 2OZ2A 4BPVA 2B1MA 3HHIA 4G54A 2DJGB 3OISA 3NHEA 3F75A 2Y6EA 5JH3A 2XU1A 3I06A 1U5IA 4PADA 3MHSA 4FK5A 5J94A 3QT4A 4P6EA 1JQPA 2BDZA 5CVNB 1ME3A 1CS8A 3KWZA 2OULA 1CJLA 2P7UA 3N3GA 2IPPB 3KX1A 3H6SA 1ATKA 4W5CA 1U9WA
chains in the Genus database with same CATH superfamily
2FRQA 1KFUL 1ITOA 2HHNA 4RF1A 3MTVA 2YJCA 3OVXA 2FTDA 2VHFA 3IMAA 4CDFB 6PADA 3MP2A 4QH6A 1F2BA 2DOSA 2FYEA 2PADA 2FE8A 3WXEA 4FJCA 4XUIA 1PPDA 4X6IA 4AXMA 3BWKA 1CSBB 4YYRA 1EWOA 3E1ZB 1NL6A 1ICFA 1AYWA 2PBHA 2XU4A 2JRIA 4X6HA 5JA7A 3MJ5A 5PADA 3OF9A 4D8EA 2XU5A 2ARYA 4BOQA 1M6DA 1XKGA 3WXFA 2HWKA 1STFE 1MDWA 3IHPA 3ERVA 3CBKA 2AYNA 4QBBA 3DF0A 1KFXL 2E03A 4ZTBA 2VHSA 2DZYA 3C9EA 1ME4A 3O65A 5K16A 4N8WA 1AU4A 1Y08A 3PNRA 1KHQA 1VJVA 1YT7A 3O1GA 1CB5A 2YJBA 1THEA 1YALA 2C0YA 3PDFA 2FRAA 3TMPA 2G6DA 1NLJA 1AYUA 1Y4HA 3HD3A 2AIMA 3KKUA 2BTWB 3C0RA 4RF0A 5E6JA 5EZSA 4RKXA 1MHWA 2OP3A 2BU3A 2IBIA 4D8BA 3RVWA 1YZBA 4PP2E 1SP4B 3H7DA 2ATOA 3F5VA 5EGWA 1GCBA 1PXVA 3PW3A 5EZQA 4PP1A 1PADA 2NQAA 4DMXA 2G8EA 4PT5A 2JTCA 2B1NA 4QRGA 4X6JA 1AU2A 4OW0A 2DJFB 1MEGA 3KWBX 2DC6A 1DF0A 1Q6KA 4D8IA 1YK8A 1TL9A 3MTNA 1GMYA 3V6EA 2DZZA 2DC8A 1ZCMA 3S3QA 3KW9A 2AU1A 3CH3X 3PT2A 3PHWA 3IOQA 1F29A 2GHUA 2DCBA 3P5VA 4MM3B 2R9FA 4I07A 1K3BB 5EF4A 3RNVA 1POPA 1BY8A 2HXZA 1SNKA 4HWYA 4HXDB 2CB5A 4OVZB 1QXPA 5CVOB 2PREA 1YVBA 2PNSA 4QRXA 4ZUXU 3IEJA 3H8CA 1CPJA 1GECE 3U8EA 3W31A 4GUAA 4YYSA 1NB5A 1U9XA 5JZEA 3ZNHA 1NQCA 3BB7A 3D6SA 3IUTA 1PBHA 4MI7A 4R3DA 3MHHA 4WURA 3HHAA 2AUXA 1PVJA 3M99A 3BC3A 3USVA 2YJ9A 4BS5A 2F1GA 4CDCB 3BY4A 4M0WA 4W4UA 4YYQA 1MS6A 2JQGR 3K9MA 1AYVA 2XU3A 2YJ8A 4MZOA 3E9SA 3PRPA 1PE6A 3RVVA 3K8UA 4KLBA 4MSXA 1KHPA 3H8BA 9PAPA 4K7CA 3IV2A 2R9NA 2FT2A 2P86A 1QDQA 1EWPA 3H89A 1QMYA 1U9VA 2AS8A 4YYUA 1ZIVA 2ACTA 1PPNA 2R9OA 1EWMA 2AYOA 2AUZA 3BCNA 4RY2A 1KXRA 2NQGA 3CBJA 3LXSA 4YYVA 3P5UA 2G7YA 3BPFA 4N79A 3BPMA 4MZSA 4BOUA 3PHXA 3CH2X 2DC9A 5A24A 2Z84A 4PI3A 3IFUA 3OVZA 2HH5A 3GCBA 3KSEA 3HWNA 4CDEB 2R6NA 3QJ3A 4Q8GA 1PCIA 4AXLA 1EF7A 1AIMA 1UKFA 3OF8A 2E00A 3AI8A 5CHVA 1F2AA 1DKIA 3BBAA 2E01A 3PRMA 5KO3A 3QSDA 1S4VA 1X9YA 1MIRA 1TLOA 1PIPA 1EWLA 4RNAA 1MEMA 4FIPA 2H7JA 2CIOA 5CHTA 1CQDA 2BDLA 2J7QC 4IUMA 4YVAA 2O6XA 3BOWA 4Q8HA 1CTEA 2G8JA 3KFQA 1QOLA 2F7DA 4XZXA 4BQVA 3B79A 2DC7A 1TU6A 4I05A 3RVXA 4CDDB 2JQFR 2BTWA 1AU3A 2J7QA 1A6RA 1CVZA 1NB3A 1F2CA 2AVWA 1VSNA 2HD5A 1GLOA 1HUCB 5CVMA 3O0UA 3OQCA 4CZWA 1BP4A 3TRKA 1NPZA 2YJ2A 4P6GA 2DCCA 1CV8A 1PPPA 3B21A 2Y5BA 1BQIA 4WA6A 3I3TA 2P0RA 2GFOA 4BOZA 3PBHA 2DCAA 4BOPA 7PCKA 1FH0A 2NQIA 2E02A 4IP3A 4QRVA 1AU0A 3N3KA 4DMYA 2R9MA 3K24A 4BOSA 3TNXA 3N4CA 4W5BA 4A5UA 3P5WA 4BSQA 3LFYA 5F02A 3WXGA 2DCDA 4OEMA 3V6CA 3S3RA 2FO5A 4I04A 2AGAA 2NQDB 1U9QX 1IWDA 2R9CA 4YV8A 4XR7A 4OVZA 3ZUAA 4YYWA 4OELA 1AECA 4N4ZA 1BGOA 1O0EA 3MORA 5FPWA 2FUDA 1DEUA 3P5XA 2WBFX 8PCHA 4BS6A 3PHUA 1YK7A 2FQ9A 1PPOA 2OZ2A 4BPVA 2B1MA 3HHIA 4G54A 3W30A 2DJGB 3OISA 3NHEA 3F75A 2Y6EA 5JH3A 2XU1A 3I06A 1U5IA 4PADA 3MHSA 4FK5A 5J94A 3QT4A 4P16A 2UZJA 4P6EA 4REZA 1JQPA 2BDZA 5CVNB 1ME3A 1CS8A 3KWZA 2OULA 1CJLA 2P7UA 3N3GA 2IPPB 3KX1A 3H6SA 3PSEA 1ATKA 4W5CA 1U9WA
chains in the Genus database with same CATH topology
2FRQA 1KFUL 1ITOA 2HHNA 2YJCA 3OVXA 2FTDA 2VHFA 3IMAA 4CDFB 6PADA 4QH6A 1F2BA 2FYEA 2PADA 3WXEA 4FJCA 4XUIA 1PPDA 4X6IA 4AXMA 3BWKA 1CSBB 4YYRA 1EWOA 3E1ZB 1NL6A 1ICFA 1AYWA 2PBHA 2XU4A 4NV7A 4X6HA 5JA7A 5PADA 3OF9A 2XU5A 2ARYA 1M6DA 1XKGA 3WXFA 1STFE 1MDWA 3IHPA 3ERVA 3CBKA 2AYNA 4QBBA 3DF0A 1KFXL 2E03A 2VHSA 2DZYA 3C9EA 1ME4A 5K16A 4N8WA 1AU4A 1Y08A 3PNRA 1KHQA 1VJVA 1YT7A 3O1GA 1CB5A 2YJBA 1THEA 1YALA 2C0YA 3PDFA 2FRAA 2G6DA 1NLJA 1AYUA 1Y4HA 3HD3A 2AIMA 3KKUA 1MHWA 2OP3A 2IBIA 3RVWA 4PP2E 1SP4B 3H7DA 2ATOA 3F5VA 5EGWA 1GCBA 1PXVA 3PW3A 4PP1A 1PADA 2NQAA 4DMXA 2G8EA 2B1NA 4QRGA 4X6JA 1AU2A 2DJFB 1MEGA 3KWBX 4C5PA 2DC6A 1DF0A 1Q6KA 1YK8A 1TL9A 3MTNA 1GMYA 3V6EA 2DZZA 2DC8A 1ZCMA 3S3QA 3KW9A 2AU1A 3CH3X 3IOQA 1F29A 2GHUA 2DCBA 3P5VA 2R9FA 4I07A 1K3BB 5EF4A 1POPA 1BY8A 2HXZA 1SNKA 4HWYA 2CB5A 1QXPA 5CVOB 2PREA 1YVBA 2PNSA 4QRXA 4ZUXU 3IEJA 3H8CA 1CPJA 1W6FA 1GECE 3U8EA 4YYSA 1NB5A 1U9XA 1E2TA 1NQCA 4B55A 3D6SA 3IUTA 2BSZA 1PBHA 3MHHA 3HHAA 2AUXA 3USVA 3M99A 3BC3A 2YJ9A 2VFBA 4BS5A 2F1GA 4CDCB 4W4UA 4YYQA 1MS6A 2JQGR 3K9MA 1AYVA 2XU3A 2YJ8A 4MZOA 1PE6A 3RVVA 3K8UA 4KLBA 4MSXA 1KHPA 3H8BA 9PAPA 4K7CA 3IV2A 2R9NA 2FT2A 2P86A 1QDQA 1EWPA 3H89A 1QMYA 1U9VA 2AS8A 4YYUA 1ZIVA 2ACTA 1PPNA 2R9OA 1EWMA 2AYOA 2AUZA 3BCNA 4RY2A 1KXRA 2NQGA 3CBJA 3LXSA 4YYVA 3P5UA 2G7YA 3BPFA 4N79A 4NV8A 3BPMA 4MZSA 3CH2X 2DC9A 3D9WA 5A24A 4PI3A 3OVZA 2HH5A 3GCBA 3KSEA 3HWNA 4CDEB 2R6NA 3QJ3A 4Q8GA 1PCIA 4AXLA 1EF7A 1AIMA 3OF8A 2E00A 3AI8A 5CHVA 1F2AA 2E01A 3QSDA 1S4VA 1X9YA 1MIRA 1TLOA 1PIPA 1EWLA 1MEMA 4FIPA 2H7JA 2CIOA 5CHTA 1CQDA 2BDLA 4BGFA 3LTWA 4YVAA 2O6XA 3BOWA 4Q8HA 1CTEA 2G8JA 3KFQA 1QOLA 2F7DA 4BQVA 3B79A 2DC7A 1TU6A 4I05A 3RVXA 4CDDB 2JQFR 1AU3A 1A6RA 1CVZA 1NB3A 1F2CA 2AVWA 1VSNA 2HD5A 1GLOA 1HUCB 5CVMA 3O0UA 4CZWA 1BP4A 1NPZA 2YJ2A 4P6GA 2DCCA 1CV8A 1PPPA 2Y5BA 1BQIA 4WA6A 3I3TA 2P0RA 2GFOA 3PBHA 2DCAA 7PCKA 2VFCA 1FH0A 2NQIA 2E02A 4QRVA 1AU0A 3N3KA 4DMYA 2R9MA 3K24A 1GX3A 3TNXA 3N4CA 4W5BA 4BSQA 3P5WA 3LFYA 5F02A 3WXGA 2DCDA 4OEMA 3V6CA 3S3RA 2FO5A 4I04A 2NQDB 1U9QX 1IWDA 2R9CA 4YV8A 4XR7A 3ZUAA 4YYWA 4OELA 1AECA 4N4ZA 1BGOA 1O0EA 3MORA 5FPWA 2FUDA 1DEUA 3P5XA 2WBFX 8PCHA 4BS6A 1YK7A 2FQ9A 1PPOA 2OZ2A 4BPVA 1W4TA 2B1MA 3HHIA 4G54A 2DJGB 3OISA 3NHEA 3F75A 2Y6EA 5JH3A 2XU1A 3I06A 1U5IA 4PADA 3MHSA 4FK5A 5J94A 3QT4A 4P6EA 1JQPA 2BDZA 5CVNB 1ME3A 1CS8A 3KWZA 4GUZA 2OULA 1CJLA 2P7UA 1W5RA 3N3GA 2IPPB 3KX1A 3H6SA 1ATKA 4W5CA 1U9WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FRQ A;  1KFU L;  1ITO A;  2HHN A;  2YJC A;  3OVX A;  2FTD A;  2VHF A;  3IMA A;  4CDF B;  6PAD A;  4QH6 A;  1F2B A;  2FYE A;  2PAD A;  3WXE A;  4FJC A;  4XUI A;  1PPD A;  4X6I A;  4AXM A;  3BWK A;  1CSB B;  4YYR A;  1EWO A;  3E1Z B;  1NL6 A;  1ICF A;  1AYW A;  2PBH A;  2XU4 A;  4X6H A;  5JA7 A;  5PAD A;  3OF9 A;  2XU5 A;  2ARY A;  1M6D A;  1XKG A;  3WXF A;  1STF E;  1MDW A;  3IHP A;  3ERV A;  3CBK A;  2AYN A;  4QBB A;  3DF0 A;  1KFX L;  2E03 A;  2VHS A;  2DZY A;  3C9E A;  1ME4 A;  5K16 A;  4N8W A;  1AU4 A;  1Y08 A;  3PNR A;  1KHQ A;  1VJV A;  1YT7 A;  3O1G A;  1CB5 A;  2YJB A;  1THE A;  1YAL A;  2C0Y A;  3PDF A;  2FRA A;  2G6D A;  1NLJ A;  1AYU A;  1Y4H A;  3HD3 A;  2AIM A;  3KKU A;  1MHW A;  2OP3 A;  2IBI A;  3RVW A;  4PP2 E;  1SP4 B;  3H7D A;  2ATO A;  3F5V A;  5EGW A;  1GCB A;  1PXV A;  3PW3 A;  4PP1 A;  1PAD A;  2NQA A;  4DMX A;  2G8E A;  2B1N A;  4QRG A;  4X6J A;  1AU2 A;  2DJF B;  1MEG A;  3KWB X;  2DC6 A;  1DF0 A;  1Q6K A;  1YK8 A;  1TL9 A;  3MTN A;  1GMY A;  3V6E A;  2DZZ A;  2DC8 A;  1ZCM A;  3S3Q A;  3KW9 A;  2AU1 A;  3CH3 X;  3IOQ A;  1F29 A;  2GHU A;  2DCB A;  3P5V A;  2R9F A;  4I07 A;  1K3B B;  5EF4 A;  1POP A;  1BY8 A;  2HXZ A;  1SNK A;  4HWY A;  2CB5 A;  1QXP A;  5CVO B;  2PRE A;  1YVB A;  2PNS A;  4QRX A;  4ZUX U;  3IEJ A;  3H8C A;  1CPJ A;  1GEC E;  3U8E A;  4YYS A;  1NB5 A;  1U9X A;  1NQC A;  3D6S A;  3IUT A;  1PBH A;  3MHH A;  3HHA A;  2AUX A;  3USV A;  3M99 A;  3BC3 A;  2YJ9 A;  4BS5 A;  2F1G A;  4CDC B;  4W4U A;  4YYQ A;  1MS6 A;  2JQG R;  3K9M A;  1AYV A;  2XU3 A;  2YJ8 A;  4MZO A;  1PE6 A;  3RVV A;  3K8U A;  4KLB A;  4MSX A;  1KHP A;  3H8B A;  9PAP A;  4K7C A;  3IV2 A;  2R9N A;  2FT2 A;  2P86 A;  1QDQ A;  1EWP A;  3H89 A;  1QMY A;  1U9V A;  2AS8 A;  4YYU A;  1ZIV A;  2ACT A;  1PPN A;  2R9O A;  1EWM A;  2AYO A;  2AUZ A;  3BCN A;  4RY2 A;  1KXR A;  2NQG A;  3CBJ A;  3LXS A;  4YYV A;  3P5U A;  2G7Y A;  3BPF A;  4N79 A;  3BPM A;  4MZS A;  3CH2 X;  2DC9 A;  5A24 A;  4PI3 A;  3OVZ A;  2HH5 A;  3GCB A;  3KSE A;  3HWN A;  4CDE B;  2R6N A;  3QJ3 A;  4Q8G A;  1PCI A;  4AXL A;  1EF7 A;  1AIM A;  3OF8 A;  2E00 A;  3AI8 A;  5CHV A;  1F2A A;  2E01 A;  3QSD A;  1S4V A;  1X9Y A;  1MIR A;  1TLO A;  1PIP A;  1EWL A;  1MEM A;  4FIP A;  2H7J A;  2CIO A;  5CHT A;  1CQD A;  2BDL A;  4YVA A;  2O6X A;  3BOW A;  4Q8H A;  1CTE A;  2G8J A;  3KFQ A;  1QOL A;  2F7D A;  4BQV A;  3B79 A;  2DC7 A;  1TU6 A;  4I05 A;  3RVX A;  4CDD B;  2JQF R;  1AU3 A;  1A6R A;  1CVZ A;  1NB3 A;  1F2C A;  2AVW A;  1VSN A;  2HD5 A;  1GLO A;  1HUC B;  5CVM A;  3O0U A;  4CZW A;  1BP4 A;  1NPZ A;  2YJ2 A;  4P6G A;  2DCC A;  1CV8 A;  1PPP A;  2Y5B A;  1BQI A;  4WA6 A;  3I3T A;  2P0R A;  2GFO A;  3PBH A;  2DCA A;  7PCK A;  1FH0 A;  2NQI A;  2E02 A;  4QRV A;  1AU0 A;  3N3K A;  4DMY A;  2R9M A;  3K24 A;  3TNX A;  3N4C A;  4W5B A;  4BSQ A;  3P5W A;  3LFY A;  5F02 A;  3WXG A;  2DCD A;  4OEM A;  3V6C A;  3S3R A;  2FO5 A;  4I04 A;  2NQD B;  1U9Q X;  1IWD A;  2R9C A;  4YV8 A;  4XR7 A;  3ZUA A;  4YYW A;  4OEL A;  1AEC A;  4N4Z A;  1BGO A;  1O0E A;  3MOR A;  5FPW A;  2FUD A;  1DEU A;  3P5X A;  2WBF X;  8PCH A;  4BS6 A;  1YK7 A;  2FQ9 A;  1PPO A;  2OZ2 A;  4BPV A;  2B1M A;  3HHI A;  4G54 A;  2DJG B;  3OIS A;  3NHE A;  3F75 A;  2Y6E A;  5JH3 A;  2XU1 A;  3I06 A;  1U5I A;  4PAD A;  3MHS A;  4FK5 A;  5J94 A;  3QT4 A;  4P6E A;  1JQP A;  2BDZ A;  5CVN B;  1ME3 A;  1CS8 A;  3KWZ A;  2OUL A;  1CJL A;  2P7U A;  3N3G A;  2IPP B;  3KX1 A;  3H6S A;  1ATK A;  4W5C A;  1U9W A; 
#chains in the Genus database with same CATH topology
 2FRQ A;  1KFU L;  1ITO A;  2HHN A;  4RF1 A;  3MTV A;  2YJC A;  3OVX A;  2FTD A;  2VHF A;  3IMA A;  4CDF B;  6PAD A;  3MP2 A;  4QH6 A;  1F2B A;  2DOS A;  2FYE A;  2PAD A;  2FE8 A;  3WXE A;  4FJC A;  4XUI A;  1PPD A;  4X6I A;  4AXM A;  3BWK A;  1CSB B;  4YYR A;  1EWO A;  3E1Z B;  1NL6 A;  1ICF A;  1AYW A;  2PBH A;  2XU4 A;  2JRI A;  4X6H A;  5JA7 A;  3MJ5 A;  5PAD A;  3OF9 A;  4D8E A;  2XU5 A;  2ARY A;  4BOQ A;  1M6D A;  1XKG A;  3WXF A;  2HWK A;  1STF E;  1MDW A;  3IHP A;  3ERV A;  3CBK A;  2AYN A;  4QBB A;  3DF0 A;  1KFX L;  2E03 A;  4ZTB A;  2VHS A;  2DZY A;  3C9E A;  1ME4 A;  3O65 A;  5K16 A;  4N8W A;  1AU4 A;  1Y08 A;  3PNR A;  1KHQ A;  1VJV A;  1YT7 A;  3O1G A;  1CB5 A;  2YJB A;  1THE A;  1YAL A;  2C0Y A;  3PDF A;  2FRA A;  3TMP A;  2G6D A;  1NLJ A;  1AYU A;  1Y4H A;  3HD3 A;  2AIM A;  3KKU A;  2BTW B;  3C0R A;  4RF0 A;  5E6J A;  5EZS A;  4RKX A;  1MHW A;  2OP3 A;  2BU3 A;  2IBI A;  4D8B A;  3RVW A;  1YZB A;  4PP2 E;  1SP4 B;  3H7D A;  2ATO A;  3F5V A;  5EGW A;  1GCB A;  1PXV A;  3PW3 A;  5EZQ A;  4PP1 A;  1PAD A;  2NQA A;  4DMX A;  2G8E A;  4PT5 A;  2JTC A;  2B1N A;  4QRG A;  4X6J A;  1AU2 A;  4OW0 A;  2DJF B;  1MEG A;  3KWB X;  2DC6 A;  1DF0 A;  1Q6K A;  4D8I A;  1YK8 A;  1TL9 A;  3MTN A;  1GMY A;  3V6E A;  2DZZ A;  2DC8 A;  1ZCM A;  3S3Q A;  3KW9 A;  2AU1 A;  3CH3 X;  3PT2 A;  3PHW A;  3IOQ A;  1F29 A;  2GHU A;  2DCB A;  3P5V A;  4MM3 B;  2R9F A;  4I07 A;  1K3B B;  5EF4 A;  3RNV A;  1POP A;  1BY8 A;  2HXZ A;  1SNK A;  4HWY A;  4HXD B;  2CB5 A;  4OVZ B;  1QXP A;  5CVO B;  2PRE A;  1YVB A;  2PNS A;  4QRX A;  4ZUX U;  3IEJ A;  3H8C A;  1CPJ A;  1GEC E;  3U8E A;  3W31 A;  4GUA A;  4YYS A;  1NB5 A;  1U9X A;  5JZE A;  3ZNH A;  1NQC A;  3BB7 A;  3D6S A;  3IUT A;  1PBH A;  4MI7 A;  4R3D A;  3MHH A;  4WUR A;  3HHA A;  2AUX A;  1PVJ A;  3M99 A;  3BC3 A;  3USV A;  2YJ9 A;  4BS5 A;  2F1G A;  4CDC B;  3BY4 A;  4M0W A;  4W4U A;  4YYQ A;  1MS6 A;  2JQG R;  3K9M A;  1AYV A;  2XU3 A;  2YJ8 A;  4MZO A;  3E9S A;  3PRP A;  1PE6 A;  3RVV A;  3K8U A;  4KLB A;  4MSX A;  1KHP A;  3H8B A;  9PAP A;  4K7C A;  3IV2 A;  2R9N A;  2FT2 A;  2P86 A;  1QDQ A;  1EWP A;  3H89 A;  1QMY A;  1U9V A;  2AS8 A;  4YYU A;  1ZIV A;  2ACT A;  1PPN A;  2R9O A;  1EWM A;  2AYO A;  2AUZ A;  3BCN A;  4RY2 A;  1KXR A;  2NQG A;  3CBJ A;  3LXS A;  4YYV A;  3P5U A;  2G7Y A;  3BPF A;  4N79 A;  3BPM A;  4MZS A;  4BOU A;  3PHX A;  3CH2 X;  2DC9 A;  5A24 A;  2Z84 A;  4PI3 A;  3IFU A;  3OVZ A;  2HH5 A;  3GCB A;  3KSE A;  3HWN A;  4CDE B;  2R6N A;  3QJ3 A;  4Q8G A;  1PCI A;  4AXL A;  1EF7 A;  1AIM A;  1UKF A;  3OF8 A;  2E00 A;  3AI8 A;  5CHV A;  1F2A A;  1DKI A;  3BBA A;  2E01 A;  3PRM A;  5KO3 A;  3QSD A;  1S4V A;  1X9Y A;  1MIR A;  1TLO A;  1PIP A;  1EWL A;  4RNA A;  1MEM A;  4FIP A;  2H7J A;  2CIO A;  5CHT A;  1CQD A;  2BDL A;  2J7Q C;  4IUM A;  4YVA A;  2O6X A;  3BOW A;  4Q8H A;  1CTE A;  2G8J A;  3KFQ A;  1QOL A;  2F7D A;  4XZX A;  4BQV A;  3B79 A;  2DC7 A;  1TU6 A;  4I05 A;  3RVX A;  4CDD B;  2JQF R;  2BTW A;  1AU3 A;  2J7Q A;  1A6R A;  1CVZ A;  1NB3 A;  1F2C A;  2AVW A;  1VSN A;  2HD5 A;  1GLO A;  1HUC B;  5CVM A;  3O0U A;  3OQC A;  4CZW A;  1BP4 A;  3TRK A;  1NPZ A;  2YJ2 A;  4P6G A;  2DCC A;  1CV8 A;  1PPP A;  3B21 A;  2Y5B A;  1BQI A;  4WA6 A;  3I3T A;  2P0R A;  2GFO A;  4BOZ A;  3PBH A;  2DCA A;  4BOP A;  7PCK A;  1FH0 A;  2NQI A;  2E02 A;  4IP3 A;  4QRV A;  1AU0 A;  3N3K A;  4DMY A;  2R9M A;  3K24 A;  4BOS A;  3TNX A;  3N4C A;  4W5B A;  4A5U A;  3P5W A;  4BSQ A;  3LFY A;  5F02 A;  3WXG A;  2DCD A;  4OEM A;  3V6C A;  3S3R A;  2FO5 A;  4I04 A;  2AGA A;  2NQD B;  1U9Q X;  1IWD A;  2R9C A;  4YV8 A;  4XR7 A;  4OVZ A;  3ZUA A;  4YYW A;  4OEL A;  1AEC A;  4N4Z A;  1BGO A;  1O0E A;  3MOR A;  5FPW A;  2FUD A;  1DEU A;  3P5X A;  2WBF X;  8PCH A;  4BS6 A;  3PHU A;  1YK7 A;  2FQ9 A;  1PPO A;  2OZ2 A;  4BPV A;  2B1M A;  3HHI A;  4G54 A;  3W30 A;  2DJG B;  3OIS A;  3NHE A;  3F75 A;  2Y6E A;  5JH3 A;  2XU1 A;  3I06 A;  1U5I A;  4PAD A;  3MHS A;  4FK5 A;  5J94 A;  3QT4 A;  4P16 A;  2UZJ A;  4P6E A;  4REZ A;  1JQP A;  2BDZ A;  5CVN B;  1ME3 A;  1CS8 A;  3KWZ A;  2OUL A;  1CJL A;  2P7U A;  3N3G A;  2IPP B;  3KX1 A;  3H6S A;  3PSE A;  1ATK A;  4W5C A;  1U9W A; 
#chains in the Genus database with same CATH homology
 2FRQ A;  1KFU L;  1ITO A;  2HHN A;  2YJC A;  3OVX A;  2FTD A;  2VHF A;  3IMA A;  4CDF B;  6PAD A;  4QH6 A;  1F2B A;  2FYE A;  2PAD A;  3WXE A;  4FJC A;  4XUI A;  1PPD A;  4X6I A;  4AXM A;  3BWK A;  1CSB B;  4YYR A;  1EWO A;  3E1Z B;  1NL6 A;  1ICF A;  1AYW A;  2PBH A;  2XU4 A;  4NV7 A;  4X6H A;  5JA7 A;  5PAD A;  3OF9 A;  2XU5 A;  2ARY A;  1M6D A;  1XKG A;  3WXF A;  1STF E;  1MDW A;  3IHP A;  3ERV A;  3CBK A;  2AYN A;  4QBB A;  3DF0 A;  1KFX L;  2E03 A;  2VHS A;  2DZY A;  3C9E A;  1ME4 A;  5K16 A;  4N8W A;  1AU4 A;  1Y08 A;  3PNR A;  1KHQ A;  1VJV A;  1YT7 A;  3O1G A;  1CB5 A;  2YJB A;  1THE A;  1YAL A;  2C0Y A;  3PDF A;  2FRA A;  2G6D A;  1NLJ A;  1AYU A;  1Y4H A;  3HD3 A;  2AIM A;  3KKU A;  1MHW A;  2OP3 A;  2IBI A;  3RVW A;  4PP2 E;  1SP4 B;  3H7D A;  2ATO A;  3F5V A;  5EGW A;  1GCB A;  1PXV A;  3PW3 A;  4PP1 A;  1PAD A;  2NQA A;  4DMX A;  2G8E A;  2B1N A;  4QRG A;  4X6J A;  1AU2 A;  2DJF B;  1MEG A;  3KWB X;  4C5P A;  2DC6 A;  1DF0 A;  1Q6K A;  1YK8 A;  1TL9 A;  3MTN A;  1GMY A;  3V6E A;  2DZZ A;  2DC8 A;  1ZCM A;  3S3Q A;  3KW9 A;  2AU1 A;  3CH3 X;  3IOQ A;  1F29 A;  2GHU A;  2DCB A;  3P5V A;  2R9F A;  4I07 A;  1K3B B;  5EF4 A;  1POP A;  1BY8 A;  2HXZ A;  1SNK A;  4HWY A;  2CB5 A;  1QXP A;  5CVO B;  2PRE A;  1YVB A;  2PNS A;  4QRX A;  4ZUX U;  3IEJ A;  3H8C A;  1CPJ A;  1W6F A;  1GEC E;  3U8E A;  4YYS A;  1NB5 A;  1U9X A;  1E2T A;  1NQC A;  4B55 A;  3D6S A;  3IUT A;  2BSZ A;  1PBH A;  3MHH A;  3HHA A;  2AUX A;  3USV A;  3M99 A;  3BC3 A;  2YJ9 A;  2VFB A;  4BS5 A;  2F1G A;  4CDC B;  4W4U A;  4YYQ A;  1MS6 A;  2JQG R;  3K9M A;  1AYV A;  2XU3 A;  2YJ8 A;  4MZO A;  1PE6 A;  3RVV A;  3K8U A;  4KLB A;  4MSX A;  1KHP A;  3H8B A;  9PAP A;  4K7C A;  3IV2 A;  2R9N A;  2FT2 A;  2P86 A;  1QDQ A;  1EWP A;  3H89 A;  1QMY A;  1U9V A;  2AS8 A;  4YYU A;  1ZIV A;  2ACT A;  1PPN A;  2R9O A;  1EWM A;  2AYO A;  2AUZ A;  3BCN A;  4RY2 A;  1KXR A;  2NQG A;  3CBJ A;  3LXS A;  4YYV A;  3P5U A;  2G7Y A;  3BPF A;  4N79 A;  4NV8 A;  3BPM A;  4MZS A;  3CH2 X;  2DC9 A;  3D9W A;  5A24 A;  4PI3 A;  3OVZ A;  2HH5 A;  3GCB A;  3KSE A;  3HWN A;  4CDE B;  2R6N A;  3QJ3 A;  4Q8G A;  1PCI A;  4AXL A;  1EF7 A;  1AIM A;  3OF8 A;  2E00 A;  3AI8 A;  5CHV A;  1F2A A;  2E01 A;  3QSD A;  1S4V A;  1X9Y A;  1MIR A;  1TLO A;  1PIP A;  1EWL A;  1MEM A;  4FIP A;  2H7J A;  2CIO A;  5CHT A;  1CQD A;  2BDL A;  4BGF A;  3LTW A;  4YVA A;  2O6X A;  3BOW A;  4Q8H A;  1CTE A;  2G8J A;  3KFQ A;  1QOL A;  2F7D A;  4BQV A;  3B79 A;  2DC7 A;  1TU6 A;  4I05 A;  3RVX A;  4CDD B;  2JQF R;  1AU3 A;  1A6R A;  1CVZ A;  1NB3 A;  1F2C A;  2AVW A;  1VSN A;  2HD5 A;  1GLO A;  1HUC B;  5CVM A;  3O0U A;  4CZW A;  1BP4 A;  1NPZ A;  2YJ2 A;  4P6G A;  2DCC A;  1CV8 A;  1PPP A;  2Y5B A;  1BQI A;  4WA6 A;  3I3T A;  2P0R A;  2GFO A;  3PBH A;  2DCA A;  7PCK A;  2VFC A;  1FH0 A;  2NQI A;  2E02 A;  4QRV A;  1AU0 A;  3N3K A;  4DMY A;  2R9M A;  3K24 A;  1GX3 A;  3TNX A;  3N4C A;  4W5B A;  4BSQ A;  3P5W A;  3LFY A;  5F02 A;  3WXG A;  2DCD A;  4OEM A;  3V6C A;  3S3R A;  2FO5 A;  4I04 A;  2NQD B;  1U9Q X;  1IWD A;  2R9C A;  4YV8 A;  4XR7 A;  3ZUA A;  4YYW A;  4OEL A;  1AEC A;  4N4Z A;  1BGO A;  1O0E A;  3MOR A;  5FPW A;  2FUD A;  1DEU A;  3P5X A;  2WBF X;  8PCH A;  4BS6 A;  1YK7 A;  2FQ9 A;  1PPO A;  2OZ2 A;  4BPV A;  1W4T A;  2B1M A;  3HHI A;  4G54 A;  2DJG B;  3OIS A;  3NHE A;  3F75 A;  2Y6E A;  5JH3 A;  2XU1 A;  3I06 A;  1U5I A;  4PAD A;  3MHS A;  4FK5 A;  5J94 A;  3QT4 A;  4P6E A;  1JQP A;  2BDZ A;  5CVN B;  1ME3 A;  1CS8 A;  3KWZ A;  4GUZ A;  2OUL A;  1CJL A;  2P7U A;  1W5R A;  3N3G A;  2IPP B;  3KX1 A;  3H6S A;  1ATK A;  4W5C A;  1U9W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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