2NQGA

Calpain 1 proteolytic core inactivated by wr18(s,s), an epoxysuccinyl-type inhibitor.
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Development of Calpain-specific Inactivators by Screening of Positional Scanning Epoxide Libraries
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 93
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2nqgA02
2XU4A 4FJCA 3IV2A 2JQGR 3MTNA 2HHNA 3LFYA 3PNRA 2Y6EA 3H8CA 2CIOA 2PBHA 3CH3X 4I05A 1U9VA 2BDZA 2FRAA 1PCIA 4BPVA 2ACTA 1NQCA 2FO5A 1BY8A 3B79A 2AUXA 2AIMA 4RY2A 3PBHA 1SNKA 3H6SA 2C0YA 3S3QA 1CTEA 4QRXA 2ARYA 1CB5A 2G8JA 4QRVA 4N8WA 1TLOA 1EF7A 3F75A 1F29A 2HXZA 3N4CA 1ME3A 3PDFA 5CVMA 5EF4A 2YJ2A 2ATOA 4BS5A 3KKUA 2R9FA 1EWLA 3ZUAA 2O6XA 2WBFX 1QMYA 4YYVA 4YYUA 1KHPA 3OF8A 5CVNB 2IPPB 1EWOA 2AYNA 3V6CA 2R9MA 1AU4A 2YJCA 4MZSA 1F2AA 4N4ZA 3P5VA 3PW3A 1YK7A 2YJ8A 2FUDA 3S3RA 1PPNA 4CDEB 4BSQA 3E1ZB 3RVVA 4BS6A 4N79A 1K3BB 4PP2E 1S4VA 4PI3A 1DF0A 1FH0A 1U9WA 3HD3A 4I04A 2H7JA 1XKGA 3BOWA 4CDFB 1Q6KA 4XUIA 3AI8A 2E03A 2R9CA 3M99A 3HHIA 1AYWA 1MEGA 5FPWA 2BDLA 5CVOB 2XU3A 3BCNA 3KX1A 4W4UA 2F7DA 2HD5A 3QJ3A 1IWDA 4FK5A 2HH5A 1ITOA 1KFUL 4QH6A 2F1GA 1YT7A 3QT4A 1CVZA 3H8BA 4P6GA 2PADA 3LXSA 2DCCA 3NHEA 1QXPA 1GECE 3IUTA 5CHVA 2XU5A 4YVAA 4YV8A 2OZ2A 5CHTA 4DMXA 3GCBA 2B1NA 1U5IA 4QBBA 2NQAA 4P6EA 3TNXA 4FIPA 2B1MA 2FTDA 3O1GA 1VSNA 3H89A 1BP4A 4QRGA 2DC6A 1CSBB 1KXRA 3DF0A 2E01A 1X9YA 1GLOA 2P0RA 4CDCB 4W5CA 2AS8A 1Y08A 2CB5A 1MDWA 3N3KA 3P5UA 1BQIA 1AIMA 5JA7A 3MHSA 4X6HA 4DMYA 3KWZA 1PPOA 4MZOA 2FYEA 2G8EA 1CJLA 2PREA 1GMYA 3BPFA 3OVZA 1M6DA 1PPDA 1MHWA 4PP1A 4PADA 3I3TA 1NPZA 2E02A 1KHQA 3ERVA 1QDQA 3BWKA 1POPA 3OVXA 1HUCB 3BPMA 3K9MA 4ZUXU 7PCKA 3IMAA 3K8UA 5JH3A 1GCBA 2VHFA 3N3GA 6PADA 1DEUA 3KSEA 2R6NA 3KFQA 1ME4A 2P86A 3IEJA 2DZZA 5PADA 2FT2A 1Y4HA 2PNSA 3BC3A 1CS8A 1KFXL 3D6SA 4X6IA 1ICFA 4XR7A 5F02A 1SP4B 3IOQA 3USVA 2FQ9A 3MORA 4Q8HA 1U9XA 2AVWA 3P5XA 1PIPA 4WA6A 1CQDA 1ZIVA 1YALA 3KW9A 3WXEA 1F2CA 1TL9A 1AYVA 4BQVA 5K16A 3OISA 8PCHA 3CH2X 1AECA 2DC9A 1CV8A 1EWPA 2VHSA 1AU3A 2E00A 4CDDB 4G54A 4AXMA 3IHPA 1NL6A 3RVXA 1A6RA 2R9OA 4OELA 4Q8GA 2G6DA 2DJFB 1ATKA 2FRQA 2G7YA 3WXGA 3HWNA 4OEMA 3F5VA 4MSXA 1VJVA 4CZWA 1QOLA 3KWBX 5J94A 5A24A 3CBKA 2AUZA 3OF9A 1PBHA 2GFOA 3MHHA 2IBIA 1F2BA 1MIRA 1ZCMA 2GHUA 4YYWA 3HHAA 1CPJA 1NB5A 3U8EA 2DC8A 3H7DA 2DCAA 4HWYA 3WXFA 1NLJA 4AXLA 2R9NA 3K24A 2Y5BA 3P5WA 4I07A 2P7UA 4YYQA 4YYSA 2YJBA 3RVWA 3C9EA 1THEA 9PAPA 4KLBA 1PPPA 2DJGB 2JQFR 1NB3A 2NQIA 3O0UA 1YVBA 2YJ9A 4K7CA 1PXVA 2DCDA 1BGOA 2NQGA 2OULA 1YK8A 4YYRA 2AYOA 1PE6A 2DC7A 1TU6A 1AU0A 2NQDB 1U9QX 2OP3A 1MEMA 3V6EA 1MS6A 1AU2A 1O0EA 1JQPA 1PADA 3CBJA 5EGWA 3QSDA 2DCBA 4W5BA 4X6JA 1STFE 2DZYA 2AU1A 1AYUA 3I06A 1EWMA 2XU1A
chains in the Genus database with same CATH superfamily
2XU4A 4FJCA 4D8BA 3IV2A 2JQGR 3W31A 3MTNA 2HHNA 3LFYA 4REZA 3PNRA 2Y6EA 3H8CA 2CIOA 2PBHA 3CH3X 4I05A 1U9VA 2BDZA 2FRAA 1PCIA 4OW0A 4BPVA 2ACTA 1NQCA 2FO5A 4WURA 1BY8A 3B79A 2AUXA 2AIMA 4RY2A 3PBHA 1SNKA 3H6SA 2C0YA 3S3QA 3C0RA 1CTEA 4QRXA 2ARYA 1CB5A 2G8JA 3MJ5A 4QRVA 4N8WA 1TLOA 1EF7A 3F75A 1F29A 2HXZA 3N4CA 1ME3A 3PDFA 4PT5A 5CVMA 2BTWB 2JTCA 5EF4A 2YJ2A 2ATOA 4BS5A 3KKUA 2R9FA 3B21A 1EWLA 3O65A 3ZUAA 2O6XA 2WBFX 1QMYA 5KO3A 4YYVA 2DOSA 1KHPA 4YYUA 2J7QC 4RNAA 3OF8A 5CVNB 2IPPB 1EWOA 2AYNA 3V6CA 2FE8A 2R9MA 3E9SA 1AU4A 2YJCA 4MZSA 1F2AA 4N4ZA 4P16A 3P5VA 3PW3A 1YK7A 2YJ8A 2FUDA 3S3RA 4RKXA 1PPNA 4CDEB 4BSQA 3E1ZB 2AGAA 3RVVA 4BS6A 4N79A 1K3BB 4PP2E 3RNVA 1S4VA 4PI3A 1DF0A 1FH0A 1U9WA 3HD3A 4I04A 2H7JA 1XKGA 3BOWA 3BY4A 4CDFB 1Q6KA 4XUIA 3AI8A 2E03A 3PT2A 2R9CA 3M99A 3HHIA 3MP2A 3PRMA 1AYWA 2Z84A 1MEGA 5FPWA 2BDLA 4RF1A 5CVOB 4GUAA 2XU3A 4BOSA 3BCNA 3KX1A 4OVZB 4W4UA 2F7DA 2HD5A 3QJ3A 1IWDA 4FK5A 2HH5A 1ITOA 5EZQA 1KFUL 4QH6A 2F1GA 1YT7A 3QT4A 1CVZA 4IUMA 3H8BA 4P6GA 2PADA 3LXSA 2DCCA 3NHEA 1QXPA 1GECE 3IUTA 3OQCA 5CHVA 2XU5A 4YVAA 4YV8A 2UZJA 2OZ2A 5CHTA 4DMXA 3GCBA 2B1NA 1U5IA 4QBBA 2NQAA 4P6EA 3TNXA 4FIPA 2B1MA 2FTDA 3O1GA 1VSNA 3H89A 1BP4A 4QRGA 2DC6A 4ZTBA 2BU3A 1CSBB 1KXRA 4D8IA 3DF0A 2E01A 1X9YA 1GLOA 2P0RA 2HWKA 4CDCB 4W5CA 2AS8A 1Y08A 2CB5A 4BOUA 1MDWA 3N3KA 3P5UA 1BQIA 1AIMA 5JA7A 3MHSA 4X6HA 1PVJA 4DMYA 3KWZA 1PPOA 4MZOA 2FYEA 2G8EA 1CJLA 2PREA 1GMYA 3BPFA 3OVZA 1M6DA 1PPDA 1MHWA 4PP1A 4PADA 3I3TA 1NPZA 4RF0A 2E02A 1KHQA 3ERVA 1QDQA 3BWKA 1POPA 3OVXA 1HUCB 3BPMA 3MTVA 3K9MA 4ZUXU 7PCKA 3IMAA 3PRPA 3PHWA 3K8UA 5JH3A 1GCBA 2VHFA 3BB7A 3N3GA 3ZNHA 6PADA 1DEUA 3KSEA 2R6NA 3KFQA 1ME4A 2P86A 4BOQA 4R3DA 3IEJA 2DZZA 4IP3A 5PADA 2FT2A 1Y4HA 2PNSA 5JZEA 3BC3A 1CS8A 1KFXL 3D6SA 4X6IA 1ICFA 4HXDB 4XR7A 5F02A 1SP4B 3IOQA 3USVA 2FQ9A 3MORA 4Q8HA 1U9XA 2AVWA 2BTWA 3P5XA 1PIPA 4WA6A 1CQDA 1ZIVA 1YALA 3KW9A 3WXEA 1F2CA 1TL9A 1AYVA 4BQVA 1UKFA 4D8EA 5K16A 3OISA 8PCHA 3CH2X 1AECA 2DC9A 3PHUA 3PSEA 1CV8A 1EWPA 3IFUA 2VHSA 4XZXA 1AU3A 2E00A 4M0WA 4CDDB 4G54A 4AXMA 3IHPA 1NL6A 3RVXA 1A6RA 2R9OA 4BOPA 4OELA 4Q8GA 2G6DA 2DJFB 1ATKA 2FRQA 2G7YA 3WXGA 3HWNA 4OEMA 3F5VA 4MSXA 1VJVA 4CZWA 1QOLA 3KWBX 5J94A 5A24A 1DKIA 3CBKA 2AUZA 3OF9A 1PBHA 5EZSA 2GFOA 3MHHA 2IBIA 1F2BA 1MIRA 1ZCMA 2GHUA 4YYWA 3HHAA 1CPJA 1NB5A 3U8EA 2DC8A 3H7DA 2DCAA 3BBAA 4HWYA 3WXFA 1NLJA 4AXLA 2R9NA 3K24A 1YZBA 2Y5BA 3P5WA 4I07A 2P7UA 4YYQA 4OVZA 4YYSA 5E6JA 2YJBA 3RVWA 3C9EA 2J7QA 1THEA 9PAPA 4KLBA 1PPPA 2DJGB 2JQFR 1NB3A 2NQIA 3O0UA 3PHXA 1YVBA 2YJ9A 4K7CA 1PXVA 2DCDA 1BGOA 2NQGA 2OULA 3TMPA 1YK8A 4YYRA 2AYOA 1PE6A 2DC7A 1TU6A 1AU0A 2NQDB 1U9QX 2OP3A 1MEMA 3V6EA 1MS6A 1AU2A 1O0EA 3TRKA 3W30A 4MI7A 1JQPA 1PADA 3CBJA 4MM3B 5EGWA 4A5UA 3QSDA 2DCBA 4W5BA 2JRIA 4X6JA 1STFE 2DZYA 2AU1A 4BOZA 1AYUA 3I06A 1EWMA 2XU1A
chains in the Genus database with same CATH topology
2XU4A 3D9WA 4FJCA 3IV2A 2JQGR 3MTNA 2HHNA 3LFYA 3PNRA 2Y6EA 3H8CA 2CIOA 2PBHA 3CH3X 4I05A 1U9VA 2BDZA 2FRAA 4BGFA 1PCIA 4BPVA 2ACTA 4GUZA 1NQCA 2FO5A 1BY8A 3B79A 2AUXA 2AIMA 4RY2A 3PBHA 1SNKA 3H6SA 2C0YA 3S3QA 1CTEA 4QRXA 2ARYA 1CB5A 2G8JA 4QRVA 4N8WA 1TLOA 1EF7A 3F75A 1F29A 2HXZA 3N4CA 1ME3A 3PDFA 5CVMA 5EF4A 2YJ2A 2ATOA 4BS5A 3KKUA 2R9FA 1EWLA 3ZUAA 2O6XA 2WBFX 1QMYA 4YYVA 4YYUA 1KHPA 1W4TA 3OF8A 5CVNB 4B55A 2IPPB 1EWOA 2AYNA 3V6CA 2R9MA 1AU4A 2YJCA 4MZSA 1F2AA 4N4ZA 3P5VA 3PW3A 1YK7A 2YJ8A 2FUDA 3S3RA 1PPNA 4CDEB 4BSQA 3E1ZB 3RVVA 4BS6A 4N79A 1K3BB 4PP2E 1S4VA 4PI3A 1DF0A 1FH0A 1U9WA 3HD3A 4I04A 2H7JA 1XKGA 3BOWA 4CDFB 1Q6KA 4XUIA 3AI8A 2E03A 2R9CA 3M99A 3HHIA 1AYWA 1MEGA 5FPWA 2BDLA 5CVOB 2XU3A 3BCNA 3KX1A 4W4UA 3LTWA 2F7DA 2HD5A 3QJ3A 1IWDA 4FK5A 2HH5A 1ITOA 1KFUL 4QH6A 2F1GA 1YT7A 3QT4A 1CVZA 3H8BA 2BSZA 4P6GA 2PADA 3LXSA 2DCCA 3NHEA 1QXPA 1GECE 3IUTA 5CHVA 2XU5A 4YVAA 4YV8A 2OZ2A 5CHTA 4DMXA 3GCBA 2B1NA 1U5IA 4QBBA 2NQAA 4P6EA 3TNXA 4FIPA 2B1MA 2FTDA 3O1GA 1VSNA 3H89A 1BP4A 4QRGA 2DC6A 1CSBB 1KXRA 3DF0A 2E01A 1X9YA 1GLOA 2P0RA 4CDCB 4W5CA 2AS8A 2VFBA 1Y08A 2CB5A 1MDWA 3N3KA 3P5UA 1BQIA 1AIMA 5JA7A 3MHSA 4X6HA 4DMYA 3KWZA 1PPOA 4MZOA 2FYEA 2G8EA 1CJLA 2PREA 1W5RA 1GMYA 3BPFA 3OVZA 1M6DA 1PPDA 1MHWA 4PP1A 4PADA 3I3TA 1NPZA 2E02A 1KHQA 3ERVA 1QDQA 3BWKA 1POPA 3OVXA 1HUCB 3BPMA 3K9MA 4ZUXU 7PCKA 3IMAA 3K8UA 5JH3A 1GCBA 2VHFA 3N3GA 6PADA 1DEUA 3KSEA 2R6NA 3KFQA 4NV7A 1ME4A 2P86A 1GX3A 3IEJA 2DZZA 5PADA 2FT2A 1Y4HA 2PNSA 3BC3A 1CS8A 1KFXL 3D6SA 4X6IA 1ICFA 4XR7A 5F02A 1SP4B 3IOQA 3USVA 2FQ9A 3MORA 4Q8HA 1U9XA 2AVWA 3P5XA 1PIPA 4WA6A 1CQDA 1ZIVA 1YALA 3KW9A 3WXEA 1F2CA 1TL9A 1AYVA 4BQVA 5K16A 3OISA 8PCHA 3CH2X 1AECA 2DC9A 1CV8A 1EWPA 2VHSA 1AU3A 2E00A 4CDDB 4G54A 4AXMA 3IHPA 1NL6A 3RVXA 1A6RA 2R9OA 4OELA 4Q8GA 2G6DA 2DJFB 1ATKA 1W6FA 2FRQA 2G7YA 3WXGA 1E2TA 3HWNA 4OEMA 3F5VA 4MSXA 1VJVA 4CZWA 1QOLA 3KWBX 5J94A 5A24A 3CBKA 2AUZA 3OF9A 1PBHA 2GFOA 3MHHA 2IBIA 1F2BA 1MIRA 1ZCMA 2GHUA 4YYWA 3HHAA 1CPJA 2VFCA 1NB5A 3U8EA 2DC8A 3H7DA 2DCAA 4HWYA 3WXFA 1NLJA 4AXLA 2R9NA 3K24A 2Y5BA 3P5WA 4I07A 2P7UA 4YYQA 4YYSA 4C5PA 2YJBA 4NV8A 3RVWA 3C9EA 1THEA 9PAPA 4KLBA 1PPPA 2DJGB 2JQFR 1NB3A 2NQIA 3O0UA 1YVBA 2YJ9A 4K7CA 1PXVA 2DCDA 1BGOA 2NQGA 2OULA 1YK8A 4YYRA 2AYOA 1PE6A 2DC7A 1TU6A 1AU0A 2NQDB 1U9QX 2OP3A 1MEMA 3V6EA 1MS6A 1AU2A 1O0EA 1JQPA 1PADA 3CBJA 5EGWA 3QSDA 2DCBA 4W5BA 4X6JA 1STFE 2DZYA 2AU1A 1AYUA 3I06A 1EWMA 2XU1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XU4 A;  4FJC A;  3IV2 A;  2JQG R;  3MTN A;  2HHN A;  3LFY A;  3PNR A;  2Y6E A;  3H8C A;  2CIO A;  2PBH A;  3CH3 X;  4I05 A;  1U9V A;  2BDZ A;  2FRA A;  1PCI A;  4BPV A;  2ACT A;  1NQC A;  2FO5 A;  1BY8 A;  3B79 A;  2AUX A;  2AIM A;  4RY2 A;  3PBH A;  1SNK A;  3H6S A;  2C0Y A;  3S3Q A;  1CTE A;  4QRX A;  2ARY A;  1CB5 A;  2G8J A;  4QRV A;  4N8W A;  1TLO A;  1EF7 A;  3F75 A;  1F29 A;  2HXZ A;  3N4C A;  1ME3 A;  3PDF A;  5CVM A;  5EF4 A;  2YJ2 A;  2ATO A;  4BS5 A;  3KKU A;  2R9F A;  1EWL A;  3ZUA A;  2O6X A;  2WBF X;  1QMY A;  4YYV A;  4YYU A;  1KHP A;  3OF8 A;  5CVN B;  2IPP B;  1EWO A;  2AYN A;  3V6C A;  2R9M A;  1AU4 A;  2YJC A;  4MZS A;  1F2A A;  4N4Z A;  3P5V A;  3PW3 A;  1YK7 A;  2YJ8 A;  2FUD A;  3S3R A;  1PPN A;  4CDE B;  4BSQ A;  3E1Z B;  3RVV A;  4BS6 A;  4N79 A;  1K3B B;  4PP2 E;  1S4V A;  4PI3 A;  1DF0 A;  1FH0 A;  1U9W A;  3HD3 A;  4I04 A;  2H7J A;  1XKG A;  3BOW A;  4CDF B;  1Q6K A;  4XUI A;  3AI8 A;  2E03 A;  2R9C A;  3M99 A;  3HHI A;  1AYW A;  1MEG A;  5FPW A;  2BDL A;  5CVO B;  2XU3 A;  3BCN A;  3KX1 A;  4W4U A;  2F7D A;  2HD5 A;  3QJ3 A;  1IWD A;  4FK5 A;  2HH5 A;  1ITO A;  1KFU L;  4QH6 A;  2F1G A;  1YT7 A;  3QT4 A;  1CVZ A;  3H8B A;  4P6G A;  2PAD A;  3LXS A;  2DCC A;  3NHE A;  1QXP A;  1GEC E;  3IUT A;  5CHV A;  2XU5 A;  4YVA A;  4YV8 A;  2OZ2 A;  5CHT A;  4DMX A;  3GCB A;  2B1N A;  1U5I A;  4QBB A;  2NQA A;  4P6E A;  3TNX A;  4FIP A;  2B1M A;  2FTD A;  3O1G A;  1VSN A;  3H89 A;  1BP4 A;  4QRG A;  2DC6 A;  1CSB B;  1KXR A;  3DF0 A;  2E01 A;  1X9Y A;  1GLO A;  2P0R A;  4CDC B;  4W5C A;  2AS8 A;  1Y08 A;  2CB5 A;  1MDW A;  3N3K A;  3P5U A;  1BQI A;  1AIM A;  5JA7 A;  3MHS A;  4X6H A;  4DMY A;  3KWZ A;  1PPO A;  4MZO A;  2FYE A;  2G8E A;  1CJL A;  2PRE A;  1GMY A;  3BPF A;  3OVZ A;  1M6D A;  1PPD A;  1MHW A;  4PP1 A;  4PAD A;  3I3T A;  1NPZ A;  2E02 A;  1KHQ A;  3ERV A;  1QDQ A;  3BWK A;  1POP A;  3OVX A;  1HUC B;  3BPM A;  3K9M A;  4ZUX U;  7PCK A;  3IMA A;  3K8U A;  5JH3 A;  1GCB A;  2VHF A;  3N3G A;  6PAD A;  1DEU A;  3KSE A;  2R6N A;  3KFQ A;  1ME4 A;  2P86 A;  3IEJ A;  2DZZ A;  5PAD A;  2FT2 A;  1Y4H A;  2PNS A;  3BC3 A;  1CS8 A;  1KFX L;  3D6S A;  4X6I A;  1ICF A;  4XR7 A;  5F02 A;  1SP4 B;  3IOQ A;  3USV A;  2FQ9 A;  3MOR A;  4Q8H A;  1U9X A;  2AVW A;  3P5X A;  1PIP A;  4WA6 A;  1CQD A;  1ZIV A;  1YAL A;  3KW9 A;  3WXE A;  1F2C A;  1TL9 A;  1AYV A;  4BQV A;  5K16 A;  3OIS A;  8PCH A;  3CH2 X;  1AEC A;  2DC9 A;  1CV8 A;  1EWP A;  2VHS A;  1AU3 A;  2E00 A;  4CDD B;  4G54 A;  4AXM A;  3IHP A;  1NL6 A;  3RVX A;  1A6R A;  2R9O A;  4OEL A;  4Q8G A;  2G6D A;  2DJF B;  1ATK A;  2FRQ A;  2G7Y A;  3WXG A;  3HWN A;  4OEM A;  3F5V A;  4MSX A;  1VJV A;  4CZW A;  1QOL A;  3KWB X;  5J94 A;  5A24 A;  3CBK A;  2AUZ A;  3OF9 A;  1PBH A;  2GFO A;  3MHH A;  2IBI A;  1F2B A;  1MIR A;  1ZCM A;  2GHU A;  4YYW A;  3HHA A;  1CPJ A;  1NB5 A;  3U8E A;  2DC8 A;  3H7D A;  2DCA A;  4HWY A;  3WXF A;  1NLJ A;  4AXL A;  2R9N A;  3K24 A;  2Y5B A;  3P5W A;  4I07 A;  2P7U A;  4YYQ A;  4YYS A;  2YJB A;  3RVW A;  3C9E A;  1THE A;  9PAP A;  4KLB A;  1PPP A;  2DJG B;  2JQF R;  1NB3 A;  2NQI A;  3O0U A;  1YVB A;  2YJ9 A;  4K7C A;  1PXV A;  2DCD A;  1BGO A;  2NQG A;  2OUL A;  1YK8 A;  4YYR A;  2AYO A;  1PE6 A;  2DC7 A;  1TU6 A;  1AU0 A;  2NQD B;  1U9Q X;  2OP3 A;  1MEM A;  3V6E A;  1MS6 A;  1AU2 A;  1O0E A;  1JQP A;  1PAD A;  3CBJ A;  5EGW A;  3QSD A;  2DCB A;  4W5B A;  4X6J A;  1STF E;  2DZY A;  2AU1 A;  1AYU A;  3I06 A;  1EWM A;  2XU1 A; 
#chains in the Genus database with same CATH topology
 2XU4 A;  4FJC A;  4D8B A;  3IV2 A;  2JQG R;  3W31 A;  3MTN A;  2HHN A;  3LFY A;  4REZ A;  3PNR A;  2Y6E A;  3H8C A;  2CIO A;  2PBH A;  3CH3 X;  4I05 A;  1U9V A;  2BDZ A;  2FRA A;  1PCI A;  4OW0 A;  4BPV A;  2ACT A;  1NQC A;  2FO5 A;  4WUR A;  1BY8 A;  3B79 A;  2AUX A;  2AIM A;  4RY2 A;  3PBH A;  1SNK A;  3H6S A;  2C0Y A;  3S3Q A;  3C0R A;  1CTE A;  4QRX A;  2ARY A;  1CB5 A;  2G8J A;  3MJ5 A;  4QRV A;  4N8W A;  1TLO A;  1EF7 A;  3F75 A;  1F29 A;  2HXZ A;  3N4C A;  1ME3 A;  3PDF A;  4PT5 A;  5CVM A;  2BTW B;  2JTC A;  5EF4 A;  2YJ2 A;  2ATO A;  4BS5 A;  3KKU A;  2R9F A;  3B21 A;  1EWL A;  3O65 A;  3ZUA A;  2O6X A;  2WBF X;  1QMY A;  5KO3 A;  4YYV A;  2DOS A;  1KHP A;  4YYU A;  2J7Q C;  4RNA A;  3OF8 A;  5CVN B;  2IPP B;  1EWO A;  2AYN A;  3V6C A;  2FE8 A;  2R9M A;  3E9S A;  1AU4 A;  2YJC A;  4MZS A;  1F2A A;  4N4Z A;  4P16 A;  3P5V A;  3PW3 A;  1YK7 A;  2YJ8 A;  2FUD A;  3S3R A;  4RKX A;  1PPN A;  4CDE B;  4BSQ A;  3E1Z B;  2AGA A;  3RVV A;  4BS6 A;  4N79 A;  1K3B B;  4PP2 E;  3RNV A;  1S4V A;  4PI3 A;  1DF0 A;  1FH0 A;  1U9W A;  3HD3 A;  4I04 A;  2H7J A;  1XKG A;  3BOW A;  3BY4 A;  4CDF B;  1Q6K A;  4XUI A;  3AI8 A;  2E03 A;  3PT2 A;  2R9C A;  3M99 A;  3HHI A;  3MP2 A;  3PRM A;  1AYW A;  2Z84 A;  1MEG A;  5FPW A;  2BDL A;  4RF1 A;  5CVO B;  4GUA A;  2XU3 A;  4BOS A;  3BCN A;  3KX1 A;  4OVZ B;  4W4U A;  2F7D A;  2HD5 A;  3QJ3 A;  1IWD A;  4FK5 A;  2HH5 A;  1ITO A;  5EZQ A;  1KFU L;  4QH6 A;  2F1G A;  1YT7 A;  3QT4 A;  1CVZ A;  4IUM A;  3H8B A;  4P6G A;  2PAD A;  3LXS A;  2DCC A;  3NHE A;  1QXP A;  1GEC E;  3IUT A;  3OQC A;  5CHV A;  2XU5 A;  4YVA A;  4YV8 A;  2UZJ A;  2OZ2 A;  5CHT A;  4DMX A;  3GCB A;  2B1N A;  1U5I A;  4QBB A;  2NQA A;  4P6E A;  3TNX A;  4FIP A;  2B1M A;  2FTD A;  3O1G A;  1VSN A;  3H89 A;  1BP4 A;  4QRG A;  2DC6 A;  4ZTB A;  2BU3 A;  1CSB B;  1KXR A;  4D8I A;  3DF0 A;  2E01 A;  1X9Y A;  1GLO A;  2P0R A;  2HWK A;  4CDC B;  4W5C A;  2AS8 A;  1Y08 A;  2CB5 A;  4BOU A;  1MDW A;  3N3K A;  3P5U A;  1BQI A;  1AIM A;  5JA7 A;  3MHS A;  4X6H A;  1PVJ A;  4DMY A;  3KWZ A;  1PPO A;  4MZO A;  2FYE A;  2G8E A;  1CJL A;  2PRE A;  1GMY A;  3BPF A;  3OVZ A;  1M6D A;  1PPD A;  1MHW A;  4PP1 A;  4PAD A;  3I3T A;  1NPZ A;  4RF0 A;  2E02 A;  1KHQ A;  3ERV A;  1QDQ A;  3BWK A;  1POP A;  3OVX A;  1HUC B;  3BPM A;  3MTV A;  3K9M A;  4ZUX U;  7PCK A;  3IMA A;  3PRP A;  3PHW A;  3K8U A;  5JH3 A;  1GCB A;  2VHF A;  3BB7 A;  3N3G A;  3ZNH A;  6PAD A;  1DEU A;  3KSE A;  2R6N A;  3KFQ A;  1ME4 A;  2P86 A;  4BOQ A;  4R3D A;  3IEJ A;  2DZZ A;  4IP3 A;  5PAD A;  2FT2 A;  1Y4H A;  2PNS A;  5JZE A;  3BC3 A;  1CS8 A;  1KFX L;  3D6S A;  4X6I A;  1ICF A;  4HXD B;  4XR7 A;  5F02 A;  1SP4 B;  3IOQ A;  3USV A;  2FQ9 A;  3MOR A;  4Q8H A;  1U9X A;  2AVW A;  2BTW A;  3P5X A;  1PIP A;  4WA6 A;  1CQD A;  1ZIV A;  1YAL A;  3KW9 A;  3WXE A;  1F2C A;  1TL9 A;  1AYV A;  4BQV A;  1UKF A;  4D8E A;  5K16 A;  3OIS A;  8PCH A;  3CH2 X;  1AEC A;  2DC9 A;  3PHU A;  3PSE A;  1CV8 A;  1EWP A;  3IFU A;  2VHS A;  4XZX A;  1AU3 A;  2E00 A;  4M0W A;  4CDD B;  4G54 A;  4AXM A;  3IHP A;  1NL6 A;  3RVX A;  1A6R A;  2R9O A;  4BOP A;  4OEL A;  4Q8G A;  2G6D A;  2DJF B;  1ATK A;  2FRQ A;  2G7Y A;  3WXG A;  3HWN A;  4OEM A;  3F5V A;  4MSX A;  1VJV A;  4CZW A;  1QOL A;  3KWB X;  5J94 A;  5A24 A;  1DKI A;  3CBK A;  2AUZ A;  3OF9 A;  1PBH A;  5EZS A;  2GFO A;  3MHH A;  2IBI A;  1F2B A;  1MIR A;  1ZCM A;  2GHU A;  4YYW A;  3HHA A;  1CPJ A;  1NB5 A;  3U8E A;  2DC8 A;  3H7D A;  2DCA A;  3BBA A;  4HWY A;  3WXF A;  1NLJ A;  4AXL A;  2R9N A;  3K24 A;  1YZB A;  2Y5B A;  3P5W A;  4I07 A;  2P7U A;  4YYQ A;  4OVZ A;  4YYS A;  5E6J A;  2YJB A;  3RVW A;  3C9E A;  2J7Q A;  1THE A;  9PAP A;  4KLB A;  1PPP A;  2DJG B;  2JQF R;  1NB3 A;  2NQI A;  3O0U A;  3PHX A;  1YVB A;  2YJ9 A;  4K7C A;  1PXV A;  2DCD A;  1BGO A;  2NQG A;  2OUL A;  3TMP A;  1YK8 A;  4YYR A;  2AYO A;  1PE6 A;  2DC7 A;  1TU6 A;  1AU0 A;  2NQD B;  1U9Q X;  2OP3 A;  1MEM A;  3V6E A;  1MS6 A;  1AU2 A;  1O0E A;  3TRK A;  3W30 A;  4MI7 A;  1JQP A;  1PAD A;  3CBJ A;  4MM3 B;  5EGW A;  4A5U A;  3QSD A;  2DCB A;  4W5B A;  2JRI A;  4X6J A;  1STF E;  2DZY A;  2AU1 A;  4BOZ A;  1AYU A;  3I06 A;  1EWM A;  2XU1 A; 
#chains in the Genus database with same CATH homology
 2XU4 A;  3D9W A;  4FJC A;  3IV2 A;  2JQG R;  3MTN A;  2HHN A;  3LFY A;  3PNR A;  2Y6E A;  3H8C A;  2CIO A;  2PBH A;  3CH3 X;  4I05 A;  1U9V A;  2BDZ A;  2FRA A;  4BGF A;  1PCI A;  4BPV A;  2ACT A;  4GUZ A;  1NQC A;  2FO5 A;  1BY8 A;  3B79 A;  2AUX A;  2AIM A;  4RY2 A;  3PBH A;  1SNK A;  3H6S A;  2C0Y A;  3S3Q A;  1CTE A;  4QRX A;  2ARY A;  1CB5 A;  2G8J A;  4QRV A;  4N8W A;  1TLO A;  1EF7 A;  3F75 A;  1F29 A;  2HXZ A;  3N4C A;  1ME3 A;  3PDF A;  5CVM A;  5EF4 A;  2YJ2 A;  2ATO A;  4BS5 A;  3KKU A;  2R9F A;  1EWL A;  3ZUA A;  2O6X A;  2WBF X;  1QMY A;  4YYV A;  4YYU A;  1KHP A;  1W4T A;  3OF8 A;  5CVN B;  4B55 A;  2IPP B;  1EWO A;  2AYN A;  3V6C A;  2R9M A;  1AU4 A;  2YJC A;  4MZS A;  1F2A A;  4N4Z A;  3P5V A;  3PW3 A;  1YK7 A;  2YJ8 A;  2FUD A;  3S3R A;  1PPN A;  4CDE B;  4BSQ A;  3E1Z B;  3RVV A;  4BS6 A;  4N79 A;  1K3B B;  4PP2 E;  1S4V A;  4PI3 A;  1DF0 A;  1FH0 A;  1U9W A;  3HD3 A;  4I04 A;  2H7J A;  1XKG A;  3BOW A;  4CDF B;  1Q6K A;  4XUI A;  3AI8 A;  2E03 A;  2R9C A;  3M99 A;  3HHI A;  1AYW A;  1MEG A;  5FPW A;  2BDL A;  5CVO B;  2XU3 A;  3BCN A;  3KX1 A;  4W4U A;  3LTW A;  2F7D A;  2HD5 A;  3QJ3 A;  1IWD A;  4FK5 A;  2HH5 A;  1ITO A;  1KFU L;  4QH6 A;  2F1G A;  1YT7 A;  3QT4 A;  1CVZ A;  3H8B A;  2BSZ A;  4P6G A;  2PAD A;  3LXS A;  2DCC A;  3NHE A;  1QXP A;  1GEC E;  3IUT A;  5CHV A;  2XU5 A;  4YVA A;  4YV8 A;  2OZ2 A;  5CHT A;  4DMX A;  3GCB A;  2B1N A;  1U5I A;  4QBB A;  2NQA A;  4P6E A;  3TNX A;  4FIP A;  2B1M A;  2FTD A;  3O1G A;  1VSN A;  3H89 A;  1BP4 A;  4QRG A;  2DC6 A;  1CSB B;  1KXR A;  3DF0 A;  2E01 A;  1X9Y A;  1GLO A;  2P0R A;  4CDC B;  4W5C A;  2AS8 A;  2VFB A;  1Y08 A;  2CB5 A;  1MDW A;  3N3K A;  3P5U A;  1BQI A;  1AIM A;  5JA7 A;  3MHS A;  4X6H A;  4DMY A;  3KWZ A;  1PPO A;  4MZO A;  2FYE A;  2G8E A;  1CJL A;  2PRE A;  1W5R A;  1GMY A;  3BPF A;  3OVZ A;  1M6D A;  1PPD A;  1MHW A;  4PP1 A;  4PAD A;  3I3T A;  1NPZ A;  2E02 A;  1KHQ A;  3ERV A;  1QDQ A;  3BWK A;  1POP A;  3OVX A;  1HUC B;  3BPM A;  3K9M A;  4ZUX U;  7PCK A;  3IMA A;  3K8U A;  5JH3 A;  1GCB A;  2VHF A;  3N3G A;  6PAD A;  1DEU A;  3KSE A;  2R6N A;  3KFQ A;  4NV7 A;  1ME4 A;  2P86 A;  1GX3 A;  3IEJ A;  2DZZ A;  5PAD A;  2FT2 A;  1Y4H A;  2PNS A;  3BC3 A;  1CS8 A;  1KFX L;  3D6S A;  4X6I A;  1ICF A;  4XR7 A;  5F02 A;  1SP4 B;  3IOQ A;  3USV A;  2FQ9 A;  3MOR A;  4Q8H A;  1U9X A;  2AVW A;  3P5X A;  1PIP A;  4WA6 A;  1CQD A;  1ZIV A;  1YAL A;  3KW9 A;  3WXE A;  1F2C A;  1TL9 A;  1AYV A;  4BQV A;  5K16 A;  3OIS A;  8PCH A;  3CH2 X;  1AEC A;  2DC9 A;  1CV8 A;  1EWP A;  2VHS A;  1AU3 A;  2E00 A;  4CDD B;  4G54 A;  4AXM A;  3IHP A;  1NL6 A;  3RVX A;  1A6R A;  2R9O A;  4OEL A;  4Q8G A;  2G6D A;  2DJF B;  1ATK A;  1W6F A;  2FRQ A;  2G7Y A;  3WXG A;  1E2T A;  3HWN A;  4OEM A;  3F5V A;  4MSX A;  1VJV A;  4CZW A;  1QOL A;  3KWB X;  5J94 A;  5A24 A;  3CBK A;  2AUZ A;  3OF9 A;  1PBH A;  2GFO A;  3MHH A;  2IBI A;  1F2B A;  1MIR A;  1ZCM A;  2GHU A;  4YYW A;  3HHA A;  1CPJ A;  2VFC A;  1NB5 A;  3U8E A;  2DC8 A;  3H7D A;  2DCA A;  4HWY A;  3WXF A;  1NLJ A;  4AXL A;  2R9N A;  3K24 A;  2Y5B A;  3P5W A;  4I07 A;  2P7U A;  4YYQ A;  4YYS A;  4C5P A;  2YJB A;  4NV8 A;  3RVW A;  3C9E A;  1THE A;  9PAP A;  4KLB A;  1PPP A;  2DJG B;  2JQF R;  1NB3 A;  2NQI A;  3O0U A;  1YVB A;  2YJ9 A;  4K7C A;  1PXV A;  2DCD A;  1BGO A;  2NQG A;  2OUL A;  1YK8 A;  4YYR A;  2AYO A;  1PE6 A;  2DC7 A;  1TU6 A;  1AU0 A;  2NQD B;  1U9Q X;  2OP3 A;  1MEM A;  3V6E A;  1MS6 A;  1AU2 A;  1O0E A;  1JQP A;  1PAD A;  3CBJ A;  5EGW A;  3QSD A;  2DCB A;  4W5B A;  4X6J A;  1STF E;  2DZY A;  2AU1 A;  1AYU A;  3I06 A;  1EWM A;  2XU1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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