2P86A

The high resolution crystal structure of rhodesain, the major cathepsin l protease from t. brucei rhodesiense, bound to inhibitor k11002
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
215
structure length
214
Chain Sequence
APAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTIDFGCGGGLMDNAFNWIVNSNGGNVFTASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLPQDEDAIAAYLAENGPLAIAVDATSFMDYNGGILTSCTSEQLDHGVLLVGYNDASNPPYWIIKNSWSNMWGEDGYIRIEKGTNQCLMNQAVSSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title THE high resolution structure of rhodesain, the major cathepsin L protease from trypanosoma brucei rhodesiense, illustrates the basis for differences in inhibition profiles from other papain family cysteine proteases
rcsb
molecule tags Hydrolase
source organism Trypanosoma brucei rhodesiense
molecule keywords Cysteine protease
total genus 64
structure length 214
sequence length 215
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2007-03-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2p86A00
2DZZA 2HH5A 1HUCB 2FTDA 1BQIA 2JQGR 2PREA 4X6IA 1K3BB 3CBKA 2NQDB 3HHIA 1AYWA 2R6NA 1GCBA 3P5UA 4DMYA 1NLJA 1EWOA 2E01A 3RVXA 1NB3A 3M99A 2DCCA 2HXZA 4FJCA 1CB5A 4BQVA 1CSBB 1PE6A 3N3KA 2OZ2A 4X6HA 1ITOA 8PCHA 1THEA 2YJBA 4QBBA 1PPDA 5CHVA 1TLOA 2G8EA 4CDDB 4Q8GA 1GLOA 2VHFA 1XKGA 3USVA 2G7YA 1PADA 3BC3A 3K9MA 2F7DA 5A24A 1ICFA 2NQAA 1YVBA 1NL6A 1STFE 2E02A 4YVAA 2B1MA 3I06A 2R9NA 4BS5A 2PBHA 1SP4B 2P7UA 1ME4A 1BY8A 2DCDA 4QRVA 3K8UA 4YYVA 2GFOA 1M6DA 4HWYA 1GECE 4P6GA 4X6JA 2DC9A 2YJ8A 5CVNB 1PPOA 1JQPA 3H8CA 2H7JA 1MEGA 1QDQA 3PBHA 3O1GA 4DMXA 2FT2A 1CQDA 2BDLA 4W5CA 2ATOA 3HHAA 1KHQA 2DC6A 5EGWA 3V6EA 2NQIA 3ZUAA 2ACTA 1X9YA 2XU5A 2HHNA 4YYSA 1CS8A 1YK7A 2BDZA 2GHUA 1MEMA 3E1ZB 4BS6A 4CZWA 3S3RA 2Y5BA 3CBJA 9PAPA 1F29A 3F75A 1F2AA 1YK8A 1CTEA 4OELA 4QRXA 3RVWA 3OVZA 2AUXA 3QJ3A 3AI8A 4YYQA 1NB5A 1MS6A 3KWZA 1F2BA 1YT7A 5F02A 1QOLA 3O0UA 1NPZA 3F5VA 1DEUA 5JH3A 3I3TA 3WXFA 4PP1A 1SNKA 3P5VA 2FRAA 5EF4A 3KX1A 1MIRA 4K7CA 3PW3A 3H6SA 1AECA 2FQ9A 3H89A 1CVZA 4XUIA 4N4ZA 2P0RA 2NQGA 3CH2X 3NHEA 3MORA 4BSQA 4WA6A 2FRQA 1ZIVA 4FIPA 3B79A 3HWNA 1PBHA 1TU6A 2WBFX 1YALA 4XR7A 2C0YA 1IWDA 4Q8HA 2PADA 4I07A 2XU4A 3D6SA 3N3GA 1CV8A 5JA7A 1KHPA 2AVWA 1AYVA 3QSDA 3OF9A 3IV2A 2OULA 2IPPB 4CDCB 4QRGA 3IEJA 1AU0A 2AU1A 1U9WA 1BP4A 4FK5A 1KFXL 1AU3A 1CJLA 1PPPA 2AUZA 3KWBX 4CDEB 3LXSA 1GMYA 2JQFR 5CHTA 2YJ9A 2IBIA 4PADA 2G6DA 3OISA 3KW9A 1U5IA 1S4VA 4PP2E 1Q6KA 4YV8A 2AS8A 2FYEA 4PI3A 2FUDA 4P6EA 3U8EA 1Y4HA 4W4UA 2DJFB 4W5BA 1ATKA 2R9MA 1F2CA 1PCIA 2YJCA 4AXLA 3OVXA 2ARYA 2DC7A 1EF7A 3IOQA 1AU4A 1MHWA 2DJGB 3H7DA 1A6RA 3BWKA 3N4CA 2OP3A 2E00A 3ERVA 1FH0A 6PADA 3C9EA 2XU3A 2CIOA 1U9QX 4I04A 4MSXA 3P5WA 5CVOB 1KFUL 3DF0A 2B1NA 3KSEA 1CPJA 1U9VA 1ZCMA 3MHHA 3GCBA 3PDFA 1AYUA 3MTNA 3MHSA 1POPA 3BCNA 2XU1A 3IUTA 2R9FA 3WXGA 4YYRA 1TL9A 7PCKA 3P5XA 2R9CA 2VHSA 3H8BA 4RY2A 1AIMA 3BOWA 4MZSA 2HD5A 1NQCA 2YJ2A 3S3QA 2DCAA 2DC8A 1DF0A 1MDWA 1PPNA 4BPVA 1EWPA 1Y08A 2E03A 2P86A 2DZYA 3PNRA 1VJVA 1QMYA 3TNXA 3QT4A 4QH6A 3BPMA 2G8JA 5J94A 2CB5A 1ME3A 3KFQA 4KLBA 3RVVA 2AYNA 2O6XA 2Y6EA 3CH3X 4CDFB 2R9OA 2FO5A 4I05A 3K24A 4N79A 1U9XA 5K16A 5PADA 2DCBA 4OEMA 1VSNA 5CVMA 4MZOA 3LFYA 3OF8A 2AIMA 1AU2A 1QXPA 4ZUXU 2F1GA 1EWMA 3HD3A 1O0EA 3IMAA 2AYOA 3BPFA 4N8WA 3KKUA 1KXRA 2PNSA 3IHPA 3WXEA 4G54A 1EWLA 3V6CA 4AXMA 1PIPA 4YYUA 1BGOA 1PXVA 5FPWA 4YYWA
chains in the Genus database with same CATH superfamily
2DZZA 2HH5A 4P16A 1HUCB 2FTDA 1BQIA 2UZJA 2JQGR 2PREA 4X6IA 1K3BB 3PHWA 4BOSA 4RF0A 3CBKA 2NQDB 3HHIA 1AYWA 2R6NA 1GCBA 3PT2A 3P5UA 4DMYA 1NLJA 3PHUA 1EWOA 2E01A 2JRIA 3RVXA 1NB3A 3M99A 2DCCA 2HXZA 4FJCA 1CB5A 4BQVA 2J7QC 1CSBB 1PE6A 3N3KA 2OZ2A 4XZXA 4X6HA 1ITOA 8PCHA 4ZTBA 1THEA 4OVZB 2YJBA 4QBBA 1PPDA 5CHVA 1TLOA 3B21A 5EZQA 2G8EA 4CDDB 4Q8GA 1GLOA 1PVJA 2VHFA 1XKGA 3USVA 2G7YA 1PADA 3BC3A 3K9MA 2F7DA 5A24A 1ICFA 2NQAA 1YVBA 1NL6A 1STFE 2E02A 4YVAA 2B1MA 5EZSA 3I06A 2R9NA 4BS5A 2PBHA 1SP4B 2P7UA 1ME4A 4IUMA 1BY8A 2DCDA 4QRVA 3K8UA 4YYVA 2GFOA 1M6DA 4HWYA 4A5UA 1GECE 4P6GA 4X6JA 2DC9A 2YJ8A 5CVNB 1PPOA 4PT5A 1JQPA 3H8CA 5E6JA 2H7JA 1MEGA 1QDQA 4HXDB 3PBHA 3O1GA 4DMXA 2FT2A 1CQDA 4IP3A 2BDLA 4W5CA 4RNAA 2ATOA 3HHAA 1KHQA 2DC6A 2BU3A 5EGWA 3PRPA 3V6EA 3PSEA 2NQIA 3ZUAA 2ACTA 1X9YA 2XU5A 2HHNA 4REZA 1CS8A 4YYSA 1YK7A 2BDZA 2GHUA 4D8IA 1MEMA 3E1ZB 4BS6A 2JTCA 4CZWA 3MP2A 2BTWB 3S3RA 2Y5BA 3CBJA 3MTVA 9PAPA 1F29A 2FE8A 3F75A 1F2AA 1YK8A 1CTEA 4OELA 4QRXA 3RVWA 3OVZA 3C0RA 2HWKA 2AUXA 3QJ3A 3AI8A 4YYQA 1NB5A 1MS6A 3KWZA 1F2BA 1YT7A 5F02A 1QOLA 3O0UA 1NPZA 3F5VA 1DEUA 5JH3A 3I3TA 3WXFA 4PP1A 1SNKA 3P5VA 2AGAA 2FRAA 5EF4A 3KX1A 1MIRA 4K7CA 3PW3A 3H6SA 1AECA 2FQ9A 3H89A 1CVZA 4XUIA 4N4ZA 4WURA 2P0RA 2NQGA 3CH2X 3NHEA 3MORA 4BSQA 4WA6A 2FRQA 2J7QA 3PHXA 4OW0A 1ZIVA 4FIPA 3B79A 3HWNA 1PBHA 1TU6A 2WBFX 1YALA 4XR7A 4MM3B 2C0YA 1IWDA 4Q8HA 2PADA 4BOZA 4I07A 2XU4A 3D6SA 3N3GA 1CV8A 5JA7A 1KHPA 2AVWA 1AYVA 3QSDA 3OF9A 3IV2A 2OULA 2IPPB 4CDCB 3PRMA 3IEJA 4QRGA 1AU0A 2AU1A 1U9WA 1BP4A 4BOUA 4FK5A 1KFXL 1AU3A 1CJLA 1PPPA 2AUZA 3KWBX 4CDEB 3LXSA 1GMYA 3E9SA 2JQFR 3W30A 5CHTA 2YJ9A 2IBIA 4PADA 2G6DA 3OISA 3KW9A 3TMPA 1U5IA 1S4VA 4PP2E 1Q6KA 4YV8A 3IFUA 2AS8A 2FYEA 4PI3A 2FUDA 4P6EA 3U8EA 1Y4HA 4W4UA 2DJFB 4RF1A 4W5BA 1ATKA 2R9MA 1F2CA 4GUAA 1PCIA 2YJCA 4AXLA 3OVXA 2ARYA 2DC7A 1EF7A 3IOQA 1AU4A 1MHWA 2DJGB 3H7DA 2BTWA 1A6RA 3BWKA 3N4CA 4D8EA 2OP3A 2E00A 4D8BA 3ERVA 1FH0A 6PADA 3C9EA 2XU3A 1DKIA 2CIOA 1U9QX 4I04A 4MSXA 3P5WA 5CVOB 1UKFA 1KFUL 4BOPA 3DF0A 2B1NA 3KSEA 1CPJA 1U9VA 1ZCMA 3MHHA 3GCBA 3PDFA 1AYUA 3MTNA 4R3DA 3MHSA 1POPA 3BCNA 2XU1A 4MI7A 4M0WA 4RKXA 3ZNHA 3IUTA 2R9FA 3W31A 3WXGA 2DOSA 4YYRA 1TL9A 4BOQA 7PCKA 3P5XA 2R9CA 2VHSA 3H8BA 4RY2A 1AIMA 3BOWA 4MZSA 2HD5A 1NQCA 2Z84A 2YJ2A 3S3QA 2DCAA 2DC8A 1DF0A 1MDWA 1PPNA 4OVZA 4BPVA 1EWPA 1Y08A 2E03A 2P86A 3TRKA 2DZYA 3PNRA 1VJVA 1QMYA 3TNXA 3QT4A 4QH6A 3BPMA 2G8JA 5J94A 2CB5A 1ME3A 3KFQA 4KLBA 1YZBA 3RVVA 3BY4A 2AYNA 3RNVA 2O6XA 2Y6EA 3CH3X 4CDFB 2R9OA 3OQCA 2FO5A 4I05A 3K24A 4N79A 1U9XA 5K16A 5PADA 2DCBA 3BBAA 4OEMA 1VSNA 3MJ5A 5CVMA 4MZOA 3LFYA 5KO3A 3OF8A 2AIMA 1AU2A 1QXPA 4ZUXU 2F1GA 1EWMA 3HD3A 1O0EA 3IMAA 2AYOA 3BPFA 4N8WA 3KKUA 1KXRA 2PNSA 3IHPA 3WXEA 4G54A 1EWLA 3V6CA 4AXMA 3O65A 3BB7A 1PIPA 4YYUA 1BGOA 1PXVA 5JZEA 5FPWA 4YYWA
chains in the Genus database with same CATH topology
2DZZA 2HH5A 1HUCB 2FTDA 1BQIA 2JQGR 2PREA 4X6IA 1K3BB 3CBKA 2NQDB 3HHIA 1AYWA 2R6NA 1GCBA 3P5UA 4DMYA 1NLJA 1EWOA 2E01A 3RVXA 1NB3A 3M99A 2DCCA 2HXZA 4FJCA 1CB5A 4BQVA 1CSBB 1PE6A 3N3KA 2OZ2A 4X6HA 1ITOA 8PCHA 1THEA 2YJBA 4QBBA 1PPDA 5CHVA 1TLOA 2G8EA 4CDDB 4Q8GA 1GLOA 2VHFA 1XKGA 3USVA 2G7YA 1PADA 3BC3A 3K9MA 2F7DA 5A24A 1ICFA 2NQAA 1YVBA 1NL6A 1STFE 2E02A 4YVAA 2B1MA 3I06A 2R9NA 4BS5A 2PBHA 1SP4B 2P7UA 1ME4A 1BY8A 2DCDA 4B55A 4QRVA 3K8UA 4YYVA 2GFOA 1M6DA 4HWYA 1GECE 4P6GA 4X6JA 4C5PA 2DC9A 2YJ8A 5CVNB 1PPOA 1JQPA 3H8CA 2H7JA 1MEGA 1QDQA 3PBHA 3O1GA 4DMXA 2FT2A 1CQDA 2BDLA 4W5CA 2ATOA 3HHAA 1KHQA 2DC6A 5EGWA 3V6EA 2NQIA 3ZUAA 2ACTA 1X9YA 2XU5A 2HHNA 4YYSA 1CS8A 1GX3A 1YK7A 2BDZA 2GHUA 1MEMA 3E1ZB 3LTWA 4BS6A 4CZWA 4GUZA 3S3RA 2Y5BA 3CBJA 9PAPA 1F29A 3F75A 1F2AA 1YK8A 1CTEA 4OELA 4QRXA 3RVWA 3OVZA 2AUXA 3QJ3A 3AI8A 4YYQA 1NB5A 1MS6A 3KWZA 1F2BA 1YT7A 5F02A 1QOLA 3O0UA 1NPZA 3F5VA 1DEUA 5JH3A 2VFBA 3I3TA 3WXFA 4PP1A 1SNKA 3P5VA 2FRAA 5EF4A 3KX1A 1MIRA 4K7CA 3PW3A 3H6SA 3D9WA 1AECA 2FQ9A 3H89A 1CVZA 4XUIA 4N4ZA 2P0RA 2NQGA 3CH2X 3NHEA 3MORA 4BSQA 4WA6A 2FRQA 4BGFA 1ZIVA 4FIPA 3B79A 3HWNA 1PBHA 1E2TA 1TU6A 2WBFX 1YALA 4XR7A 2C0YA 1IWDA 4Q8HA 4NV8A 2PADA 4I07A 2XU4A 3D6SA 3N3GA 1CV8A 5JA7A 1KHPA 2AVWA 1AYVA 3QSDA 3OF9A 3IV2A 2OULA 2IPPB 4CDCB 4QRGA 3IEJA 1AU0A 2AU1A 2BSZA 1U9WA 1BP4A 2VFCA 4FK5A 1KFXL 1AU3A 1CJLA 1PPPA 2AUZA 3KWBX 4CDEB 3LXSA 1GMYA 2JQFR 5CHTA 2YJ9A 2IBIA 4PADA 2G6DA 3OISA 3KW9A 1U5IA 1S4VA 1W4TA 4PP2E 1Q6KA 4YV8A 2AS8A 2FYEA 4PI3A 2FUDA 4P6EA 3U8EA 1Y4HA 4W4UA 2DJFB 4W5BA 1ATKA 2R9MA 1F2CA 1PCIA 2YJCA 4AXLA 3OVXA 2ARYA 2DC7A 1EF7A 3IOQA 1AU4A 1MHWA 2DJGB 3H7DA 1A6RA 3BWKA 3N4CA 2OP3A 2E00A 3ERVA 1FH0A 6PADA 3C9EA 4NV7A 2XU3A 2CIOA 1U9QX 4I04A 4MSXA 3P5WA 5CVOB 1KFUL 3DF0A 2B1NA 3KSEA 1CPJA 1U9VA 1ZCMA 3MHHA 3GCBA 3PDFA 1AYUA 3MTNA 3MHSA 1POPA 3BCNA 2XU1A 3IUTA 2R9FA 3WXGA 4YYRA 1TL9A 7PCKA 3P5XA 2R9CA 2VHSA 3H8BA 4RY2A 1AIMA 3BOWA 4MZSA 2HD5A 1NQCA 2YJ2A 3S3QA 2DCAA 2DC8A 1DF0A 1MDWA 1PPNA 4BPVA 1EWPA 1Y08A 2E03A 2P86A 2DZYA 3PNRA 1VJVA 1QMYA 3TNXA 3QT4A 4QH6A 3BPMA 2G8JA 5J94A 2CB5A 1ME3A 3KFQA 4KLBA 3RVVA 2AYNA 2O6XA 2Y6EA 3CH3X 4CDFB 2R9OA 2FO5A 4I05A 3K24A 4N79A 1U9XA 5K16A 1W5RA 5PADA 2DCBA 4OEMA 1VSNA 5CVMA 4MZOA 1W6FA 3LFYA 3OF8A 2AIMA 1AU2A 1QXPA 4ZUXU 2F1GA 1EWMA 3HD3A 1O0EA 3IMAA 2AYOA 3BPFA 4N8WA 3KKUA 1KXRA 2PNSA 3IHPA 3WXEA 4G54A 1EWLA 3V6CA 4AXMA 1PIPA 4YYUA 1BGOA 1PXVA 5FPWA 4YYWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DZZ A;  2HH5 A;  1HUC B;  2FTD A;  1BQI A;  2JQG R;  2PRE A;  4X6I A;  1K3B B;  3CBK A;  2NQD B;  3HHI A;  1AYW A;  2R6N A;  1GCB A;  3P5U A;  4DMY A;  1NLJ A;  1EWO A;  2E01 A;  3RVX A;  1NB3 A;  3M99 A;  2DCC A;  2HXZ A;  4FJC A;  1CB5 A;  4BQV A;  1CSB B;  1PE6 A;  3N3K A;  2OZ2 A;  4X6H A;  1ITO A;  8PCH A;  1THE A;  2YJB A;  4QBB A;  1PPD A;  5CHV A;  1TLO A;  2G8E A;  4CDD B;  4Q8G A;  1GLO A;  2VHF A;  1XKG A;  3USV A;  2G7Y A;  1PAD A;  3BC3 A;  3K9M A;  2F7D A;  5A24 A;  1ICF A;  2NQA A;  1YVB A;  1NL6 A;  1STF E;  2E02 A;  4YVA A;  2B1M A;  3I06 A;  2R9N A;  4BS5 A;  2PBH A;  1SP4 B;  2P7U A;  1ME4 A;  1BY8 A;  2DCD A;  4QRV A;  3K8U A;  4YYV A;  2GFO A;  1M6D A;  4HWY A;  1GEC E;  4P6G A;  4X6J A;  2DC9 A;  2YJ8 A;  5CVN B;  1PPO A;  1JQP A;  3H8C A;  2H7J A;  1MEG A;  1QDQ A;  3PBH A;  3O1G A;  4DMX A;  2FT2 A;  1CQD A;  2BDL A;  4W5C A;  2ATO A;  3HHA A;  1KHQ A;  2DC6 A;  5EGW A;  3V6E A;  2NQI A;  3ZUA A;  2ACT A;  1X9Y A;  2XU5 A;  2HHN A;  4YYS A;  1CS8 A;  1YK7 A;  2BDZ A;  2GHU A;  1MEM A;  3E1Z B;  4BS6 A;  4CZW A;  3S3R A;  2Y5B A;  3CBJ A;  9PAP A;  1F29 A;  3F75 A;  1F2A A;  1YK8 A;  1CTE A;  4OEL A;  4QRX A;  3RVW A;  3OVZ A;  2AUX A;  3QJ3 A;  3AI8 A;  4YYQ A;  1NB5 A;  1MS6 A;  3KWZ A;  1F2B A;  1YT7 A;  5F02 A;  1QOL A;  3O0U A;  1NPZ A;  3F5V A;  1DEU A;  5JH3 A;  3I3T A;  3WXF A;  4PP1 A;  1SNK A;  3P5V A;  2FRA A;  5EF4 A;  3KX1 A;  1MIR A;  4K7C A;  3PW3 A;  3H6S A;  1AEC A;  2FQ9 A;  3H89 A;  1CVZ A;  4XUI A;  4N4Z A;  2P0R A;  2NQG A;  3CH2 X;  3NHE A;  3MOR A;  4BSQ A;  4WA6 A;  2FRQ A;  1ZIV A;  4FIP A;  3B79 A;  3HWN A;  1PBH A;  1TU6 A;  2WBF X;  1YAL A;  4XR7 A;  2C0Y A;  1IWD A;  4Q8H A;  2PAD A;  4I07 A;  2XU4 A;  3D6S A;  3N3G A;  1CV8 A;  5JA7 A;  1KHP A;  2AVW A;  1AYV A;  3QSD A;  3OF9 A;  3IV2 A;  2OUL A;  2IPP B;  4CDC B;  4QRG A;  3IEJ A;  1AU0 A;  2AU1 A;  1U9W A;  1BP4 A;  4FK5 A;  1KFX L;  1AU3 A;  1CJL A;  1PPP A;  2AUZ A;  3KWB X;  4CDE B;  3LXS A;  1GMY A;  2JQF R;  5CHT A;  2YJ9 A;  2IBI A;  4PAD A;  2G6D A;  3OIS A;  3KW9 A;  1U5I A;  1S4V A;  4PP2 E;  1Q6K A;  4YV8 A;  2AS8 A;  2FYE A;  4PI3 A;  2FUD A;  4P6E A;  3U8E A;  1Y4H A;  4W4U A;  2DJF B;  4W5B A;  1ATK A;  2R9M A;  1F2C A;  1PCI A;  2YJC A;  4AXL A;  3OVX A;  2ARY A;  2DC7 A;  1EF7 A;  3IOQ A;  1AU4 A;  1MHW A;  2DJG B;  3H7D A;  1A6R A;  3BWK A;  3N4C A;  2OP3 A;  2E00 A;  3ERV A;  1FH0 A;  6PAD A;  3C9E A;  2XU3 A;  2CIO A;  1U9Q X;  4I04 A;  4MSX A;  3P5W A;  5CVO B;  1KFU L;  3DF0 A;  2B1N A;  3KSE A;  1CPJ A;  1U9V A;  1ZCM A;  3MHH A;  3GCB A;  3PDF A;  1AYU A;  3MTN A;  3MHS A;  1POP A;  3BCN A;  2XU1 A;  3IUT A;  2R9F A;  3WXG A;  4YYR A;  1TL9 A;  7PCK A;  3P5X A;  2R9C A;  2VHS A;  3H8B A;  4RY2 A;  1AIM A;  3BOW A;  4MZS A;  2HD5 A;  1NQC A;  2YJ2 A;  3S3Q A;  2DCA A;  2DC8 A;  1DF0 A;  1MDW A;  1PPN A;  4BPV A;  1EWP A;  1Y08 A;  2E03 A;  2P86 A;  2DZY A;  3PNR A;  1VJV A;  1QMY A;  3TNX A;  3QT4 A;  4QH6 A;  3BPM A;  2G8J A;  5J94 A;  2CB5 A;  1ME3 A;  3KFQ A;  4KLB A;  3RVV A;  2AYN A;  2O6X A;  2Y6E A;  3CH3 X;  4CDF B;  2R9O A;  2FO5 A;  4I05 A;  3K24 A;  4N79 A;  1U9X A;  5K16 A;  5PAD A;  2DCB A;  4OEM A;  1VSN A;  5CVM A;  4MZO A;  3LFY A;  3OF8 A;  2AIM A;  1AU2 A;  1QXP A;  4ZUX U;  2F1G A;  1EWM A;  3HD3 A;  1O0E A;  3IMA A;  2AYO A;  3BPF A;  4N8W A;  3KKU A;  1KXR A;  2PNS A;  3IHP A;  3WXE A;  4G54 A;  1EWL A;  3V6C A;  4AXM A;  1PIP A;  4YYU A;  1BGO A;  1PXV A;  5FPW A;  4YYW A; 
#chains in the Genus database with same CATH topology
 2DZZ A;  2HH5 A;  4P16 A;  1HUC B;  2FTD A;  1BQI A;  2UZJ A;  2JQG R;  2PRE A;  4X6I A;  1K3B B;  3PHW A;  4BOS A;  4RF0 A;  3CBK A;  2NQD B;  3HHI A;  1AYW A;  2R6N A;  1GCB A;  3PT2 A;  3P5U A;  4DMY A;  1NLJ A;  3PHU A;  1EWO A;  2E01 A;  2JRI A;  3RVX A;  1NB3 A;  3M99 A;  2DCC A;  2HXZ A;  4FJC A;  1CB5 A;  4BQV A;  2J7Q C;  1CSB B;  1PE6 A;  3N3K A;  2OZ2 A;  4XZX A;  4X6H A;  1ITO A;  8PCH A;  4ZTB A;  1THE A;  4OVZ B;  2YJB A;  4QBB A;  1PPD A;  5CHV A;  1TLO A;  3B21 A;  5EZQ A;  2G8E A;  4CDD B;  4Q8G A;  1GLO A;  1PVJ A;  2VHF A;  1XKG A;  3USV A;  2G7Y A;  1PAD A;  3BC3 A;  3K9M A;  2F7D A;  5A24 A;  1ICF A;  2NQA A;  1YVB A;  1NL6 A;  1STF E;  2E02 A;  4YVA A;  2B1M A;  5EZS A;  3I06 A;  2R9N A;  4BS5 A;  2PBH A;  1SP4 B;  2P7U A;  1ME4 A;  4IUM A;  1BY8 A;  2DCD A;  4QRV A;  3K8U A;  4YYV A;  2GFO A;  1M6D A;  4HWY A;  4A5U A;  1GEC E;  4P6G A;  4X6J A;  2DC9 A;  2YJ8 A;  5CVN B;  1PPO A;  4PT5 A;  1JQP A;  3H8C A;  5E6J A;  2H7J A;  1MEG A;  1QDQ A;  4HXD B;  3PBH A;  3O1G A;  4DMX A;  2FT2 A;  1CQD A;  4IP3 A;  2BDL A;  4W5C A;  4RNA A;  2ATO A;  3HHA A;  1KHQ A;  2DC6 A;  2BU3 A;  5EGW A;  3PRP A;  3V6E A;  3PSE A;  2NQI A;  3ZUA A;  2ACT A;  1X9Y A;  2XU5 A;  2HHN A;  4REZ A;  1CS8 A;  4YYS A;  1YK7 A;  2BDZ A;  2GHU A;  4D8I A;  1MEM A;  3E1Z B;  4BS6 A;  2JTC A;  4CZW A;  3MP2 A;  2BTW B;  3S3R A;  2Y5B A;  3CBJ A;  3MTV A;  9PAP A;  1F29 A;  2FE8 A;  3F75 A;  1F2A A;  1YK8 A;  1CTE A;  4OEL A;  4QRX A;  3RVW A;  3OVZ A;  3C0R A;  2HWK A;  2AUX A;  3QJ3 A;  3AI8 A;  4YYQ A;  1NB5 A;  1MS6 A;  3KWZ A;  1F2B A;  1YT7 A;  5F02 A;  1QOL A;  3O0U A;  1NPZ A;  3F5V A;  1DEU A;  5JH3 A;  3I3T A;  3WXF A;  4PP1 A;  1SNK A;  3P5V A;  2AGA A;  2FRA A;  5EF4 A;  3KX1 A;  1MIR A;  4K7C A;  3PW3 A;  3H6S A;  1AEC A;  2FQ9 A;  3H89 A;  1CVZ A;  4XUI A;  4N4Z A;  4WUR A;  2P0R A;  2NQG A;  3CH2 X;  3NHE A;  3MOR A;  4BSQ A;  4WA6 A;  2FRQ A;  2J7Q A;  3PHX A;  4OW0 A;  1ZIV A;  4FIP A;  3B79 A;  3HWN A;  1PBH A;  1TU6 A;  2WBF X;  1YAL A;  4XR7 A;  4MM3 B;  2C0Y A;  1IWD A;  4Q8H A;  2PAD A;  4BOZ A;  4I07 A;  2XU4 A;  3D6S A;  3N3G A;  1CV8 A;  5JA7 A;  1KHP A;  2AVW A;  1AYV A;  3QSD A;  3OF9 A;  3IV2 A;  2OUL A;  2IPP B;  4CDC B;  3PRM A;  3IEJ A;  4QRG A;  1AU0 A;  2AU1 A;  1U9W A;  1BP4 A;  4BOU A;  4FK5 A;  1KFX L;  1AU3 A;  1CJL A;  1PPP A;  2AUZ A;  3KWB X;  4CDE B;  3LXS A;  1GMY A;  3E9S A;  2JQF R;  3W30 A;  5CHT A;  2YJ9 A;  2IBI A;  4PAD A;  2G6D A;  3OIS A;  3KW9 A;  3TMP A;  1U5I A;  1S4V A;  4PP2 E;  1Q6K A;  4YV8 A;  3IFU A;  2AS8 A;  2FYE A;  4PI3 A;  2FUD A;  4P6E A;  3U8E A;  1Y4H A;  4W4U A;  2DJF B;  4RF1 A;  4W5B A;  1ATK A;  2R9M A;  1F2C A;  4GUA A;  1PCI A;  2YJC A;  4AXL A;  3OVX A;  2ARY A;  2DC7 A;  1EF7 A;  3IOQ A;  1AU4 A;  1MHW A;  2DJG B;  3H7D A;  2BTW A;  1A6R A;  3BWK A;  3N4C A;  4D8E A;  2OP3 A;  2E00 A;  4D8B A;  3ERV A;  1FH0 A;  6PAD A;  3C9E A;  2XU3 A;  1DKI A;  2CIO A;  1U9Q X;  4I04 A;  4MSX A;  3P5W A;  5CVO B;  1UKF A;  1KFU L;  4BOP A;  3DF0 A;  2B1N A;  3KSE A;  1CPJ A;  1U9V A;  1ZCM A;  3MHH A;  3GCB A;  3PDF A;  1AYU A;  3MTN A;  4R3D A;  3MHS A;  1POP A;  3BCN A;  2XU1 A;  4MI7 A;  4M0W A;  4RKX A;  3ZNH A;  3IUT A;  2R9F A;  3W31 A;  3WXG A;  2DOS A;  4YYR A;  1TL9 A;  4BOQ A;  7PCK A;  3P5X A;  2R9C A;  2VHS A;  3H8B A;  4RY2 A;  1AIM A;  3BOW A;  4MZS A;  2HD5 A;  1NQC A;  2Z84 A;  2YJ2 A;  3S3Q A;  2DCA A;  2DC8 A;  1DF0 A;  1MDW A;  1PPN A;  4OVZ A;  4BPV A;  1EWP A;  1Y08 A;  2E03 A;  2P86 A;  3TRK A;  2DZY A;  3PNR A;  1VJV A;  1QMY A;  3TNX A;  3QT4 A;  4QH6 A;  3BPM A;  2G8J A;  5J94 A;  2CB5 A;  1ME3 A;  3KFQ A;  4KLB A;  1YZB A;  3RVV A;  3BY4 A;  2AYN A;  3RNV A;  2O6X A;  2Y6E A;  3CH3 X;  4CDF B;  2R9O A;  3OQC A;  2FO5 A;  4I05 A;  3K24 A;  4N79 A;  1U9X A;  5K16 A;  5PAD A;  2DCB A;  3BBA A;  4OEM A;  1VSN A;  3MJ5 A;  5CVM A;  4MZO A;  3LFY A;  5KO3 A;  3OF8 A;  2AIM A;  1AU2 A;  1QXP A;  4ZUX U;  2F1G A;  1EWM A;  3HD3 A;  1O0E A;  3IMA A;  2AYO A;  3BPF A;  4N8W A;  3KKU A;  1KXR A;  2PNS A;  3IHP A;  3WXE A;  4G54 A;  1EWL A;  3V6C A;  4AXM A;  3O65 A;  3BB7 A;  1PIP A;  4YYU A;  1BGO A;  1PXV A;  5JZE A;  5FPW A;  4YYW A; 
#chains in the Genus database with same CATH homology
 2DZZ A;  2HH5 A;  1HUC B;  2FTD A;  1BQI A;  2JQG R;  2PRE A;  4X6I A;  1K3B B;  3CBK A;  2NQD B;  3HHI A;  1AYW A;  2R6N A;  1GCB A;  3P5U A;  4DMY A;  1NLJ A;  1EWO A;  2E01 A;  3RVX A;  1NB3 A;  3M99 A;  2DCC A;  2HXZ A;  4FJC A;  1CB5 A;  4BQV A;  1CSB B;  1PE6 A;  3N3K A;  2OZ2 A;  4X6H A;  1ITO A;  8PCH A;  1THE A;  2YJB A;  4QBB A;  1PPD A;  5CHV A;  1TLO A;  2G8E A;  4CDD B;  4Q8G A;  1GLO A;  2VHF A;  1XKG A;  3USV A;  2G7Y A;  1PAD A;  3BC3 A;  3K9M A;  2F7D A;  5A24 A;  1ICF A;  2NQA A;  1YVB A;  1NL6 A;  1STF E;  2E02 A;  4YVA A;  2B1M A;  3I06 A;  2R9N A;  4BS5 A;  2PBH A;  1SP4 B;  2P7U A;  1ME4 A;  1BY8 A;  2DCD A;  4B55 A;  4QRV A;  3K8U A;  4YYV A;  2GFO A;  1M6D A;  4HWY A;  1GEC E;  4P6G A;  4X6J A;  4C5P A;  2DC9 A;  2YJ8 A;  5CVN B;  1PPO A;  1JQP A;  3H8C A;  2H7J A;  1MEG A;  1QDQ A;  3PBH A;  3O1G A;  4DMX A;  2FT2 A;  1CQD A;  2BDL A;  4W5C A;  2ATO A;  3HHA A;  1KHQ A;  2DC6 A;  5EGW A;  3V6E A;  2NQI A;  3ZUA A;  2ACT A;  1X9Y A;  2XU5 A;  2HHN A;  4YYS A;  1CS8 A;  1GX3 A;  1YK7 A;  2BDZ A;  2GHU A;  1MEM A;  3E1Z B;  3LTW A;  4BS6 A;  4CZW A;  4GUZ A;  3S3R A;  2Y5B A;  3CBJ A;  9PAP A;  1F29 A;  3F75 A;  1F2A A;  1YK8 A;  1CTE A;  4OEL A;  4QRX A;  3RVW A;  3OVZ A;  2AUX A;  3QJ3 A;  3AI8 A;  4YYQ A;  1NB5 A;  1MS6 A;  3KWZ A;  1F2B A;  1YT7 A;  5F02 A;  1QOL A;  3O0U A;  1NPZ A;  3F5V A;  1DEU A;  5JH3 A;  2VFB A;  3I3T A;  3WXF A;  4PP1 A;  1SNK A;  3P5V A;  2FRA A;  5EF4 A;  3KX1 A;  1MIR A;  4K7C A;  3PW3 A;  3H6S A;  3D9W A;  1AEC A;  2FQ9 A;  3H89 A;  1CVZ A;  4XUI A;  4N4Z A;  2P0R A;  2NQG A;  3CH2 X;  3NHE A;  3MOR A;  4BSQ A;  4WA6 A;  2FRQ A;  4BGF A;  1ZIV A;  4FIP A;  3B79 A;  3HWN A;  1PBH A;  1E2T A;  1TU6 A;  2WBF X;  1YAL A;  4XR7 A;  2C0Y A;  1IWD A;  4Q8H A;  4NV8 A;  2PAD A;  4I07 A;  2XU4 A;  3D6S A;  3N3G A;  1CV8 A;  5JA7 A;  1KHP A;  2AVW A;  1AYV A;  3QSD A;  3OF9 A;  3IV2 A;  2OUL A;  2IPP B;  4CDC B;  4QRG A;  3IEJ A;  1AU0 A;  2AU1 A;  2BSZ A;  1U9W A;  1BP4 A;  2VFC A;  4FK5 A;  1KFX L;  1AU3 A;  1CJL A;  1PPP A;  2AUZ A;  3KWB X;  4CDE B;  3LXS A;  1GMY A;  2JQF R;  5CHT A;  2YJ9 A;  2IBI A;  4PAD A;  2G6D A;  3OIS A;  3KW9 A;  1U5I A;  1S4V A;  1W4T A;  4PP2 E;  1Q6K A;  4YV8 A;  2AS8 A;  2FYE A;  4PI3 A;  2FUD A;  4P6E A;  3U8E A;  1Y4H A;  4W4U A;  2DJF B;  4W5B A;  1ATK A;  2R9M A;  1F2C A;  1PCI A;  2YJC A;  4AXL A;  3OVX A;  2ARY A;  2DC7 A;  1EF7 A;  3IOQ A;  1AU4 A;  1MHW A;  2DJG B;  3H7D A;  1A6R A;  3BWK A;  3N4C A;  2OP3 A;  2E00 A;  3ERV A;  1FH0 A;  6PAD A;  3C9E A;  4NV7 A;  2XU3 A;  2CIO A;  1U9Q X;  4I04 A;  4MSX A;  3P5W A;  5CVO B;  1KFU L;  3DF0 A;  2B1N A;  3KSE A;  1CPJ A;  1U9V A;  1ZCM A;  3MHH A;  3GCB A;  3PDF A;  1AYU A;  3MTN A;  3MHS A;  1POP A;  3BCN A;  2XU1 A;  3IUT A;  2R9F A;  3WXG A;  4YYR A;  1TL9 A;  7PCK A;  3P5X A;  2R9C A;  2VHS A;  3H8B A;  4RY2 A;  1AIM A;  3BOW A;  4MZS A;  2HD5 A;  1NQC A;  2YJ2 A;  3S3Q A;  2DCA A;  2DC8 A;  1DF0 A;  1MDW A;  1PPN A;  4BPV A;  1EWP A;  1Y08 A;  2E03 A;  2P86 A;  2DZY A;  3PNR A;  1VJV A;  1QMY A;  3TNX A;  3QT4 A;  4QH6 A;  3BPM A;  2G8J A;  5J94 A;  2CB5 A;  1ME3 A;  3KFQ A;  4KLB A;  3RVV A;  2AYN A;  2O6X A;  2Y6E A;  3CH3 X;  4CDF B;  2R9O A;  2FO5 A;  4I05 A;  3K24 A;  4N79 A;  1U9X A;  5K16 A;  1W5R A;  5PAD A;  2DCB A;  4OEM A;  1VSN A;  5CVM A;  4MZO A;  1W6F A;  3LFY A;  3OF8 A;  2AIM A;  1AU2 A;  1QXP A;  4ZUX U;  2F1G A;  1EWM A;  3HD3 A;  1O0E A;  3IMA A;  2AYO A;  3BPF A;  4N8W A;  3KKU A;  1KXR A;  2PNS A;  3IHP A;  3WXE A;  4G54 A;  1EWL A;  3V6C A;  4AXM A;  1PIP A;  4YYU A;  1BGO A;  1PXV A;  5FPW A;  4YYW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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