2PBHA

Crystal structure of human procathepsin b at 3.3 angstrom resolution
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
317
structure length
317
Chain Sequence
MRSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide.
pubmed doi rcsb
molecule tags Thiol protease
source organism Homo sapiens
molecule keywords PROCATHEPSIN B
total genus 61
structure length 317
sequence length 317
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 1997-02-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08127 Propeptide_C1 Peptidase family C1 propeptide
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2pbhA00
2XU3A 4QRXA 3DF0A 1PCIA 3P5VA 2DJGB 4WA6A 3MHHA 2FRQA 4BQVA 1YVBA 2AYOA 1KXRA 1MDWA 3S3RA 3OISA 1EWPA 1EF7A 2C0YA 4DMYA 4YV8A 4YVAA 4AXLA 1S4VA 2DCBA 1F2AA 2OP3A 2DZYA 3H8CA 2FO5A 2HD5A 1O0EA 2B1MA 3F5VA 1STFE 1QXPA 4RY2A 2B1NA 1CSBB 1AIMA 3OF9A 2CIOA 1VJVA 3IEJA 2G8EA 3P5UA 4AXMA 1POPA 4X6JA 1CS8A 2OZ2A 4N8WA 2G8JA 3RVWA 2R9MA 4BS5A 1F2BA 1U9VA 3KFQA 4FJCA 2R9OA 3C9EA 3WXEA 2R9FA 2FTDA 1NB3A 4YYVA 2AVWA 5CVNB 2YJBA 2FUDA 1PE6A 1AYUA 2DCCA 4OEMA 3USVA 3P5WA 1PBHA 1Q6KA 3ERVA 2FT2A 5J94A 1U9XA 2NQAA 5A24A 1ICFA 2DCDA 1YALA 3F75A 3PNRA 3QSDA 1M6DA 1GCBA 4CDEB 4YYWA 3WXGA 2G7YA 4CDCB 2FQ9A 2GFOA 1KFXL 1MEGA 4KLBA 1CQDA 3D6SA 2DCAA 1A6RA 1HUCB 1AYWA 2YJ9A 2DZZA 1KHQA 4W5BA 2R9CA 3OVXA 1AU4A 3O0UA 3BPMA 1XKGA 4MSXA 2PADA 5CHVA 2AU1A 2P86A 1CVZA 2NQDB 4YYUA 2R6NA 3BPFA 3AI8A 2DC7A 5CHTA 3N3KA 4XR7A 2HH5A 4I07A 3IHPA 1AECA 2VHFA 6PADA 2E03A 2VHSA 2DC8A 1NB5A 2E02A 3IV2A 3KW9A 4QH6A 5EF4A 1YK7A 4FIPA 3WXFA 3ZUAA 2E01A 2PBHA 2AIMA 3TNXA 1SP4B 2E00A 4BPVA 3LXSA 3HWNA 1U9QX 2HHNA 3KX1A 3H8BA 1NQCA 3I3TA 4W5CA 1EWMA 1JQPA 3CH2X 4PI3A 2GHUA 1EWLA 4I04A 4X6IA 4CDFB 5CVMA 1QDQA 4N4ZA 3CBKA 3QJ3A 3CBJA 2DC6A 4Q8GA 3PW3A 3BOWA 1ITOA 4BS6A 4PP2E 1TLOA 1F29A 3KKUA 1TL9A 4YYSA 2ACTA 9PAPA 3OF8A 4K7CA 2P0RA 1DEUA 4FK5A 2Y5BA 1YK8A 3O1GA 1NPZA 3LFYA 1PPPA 2PNSA 1MEMA 1KFUL 3E1ZB 2YJ2A 3M99A 1Y08A 1NL6A 2H7JA 5EGWA 2JQGR 3N4CA 1CB5A 3PDFA 4N79A 3RVXA 2XU5A 1QMYA 5JH3A 2YJ8A 3IUTA 2AUZA 3MORA 4OELA 1ZIVA 4XUIA 4BSQA 2XU1A 1PPDA 4I05A 1X9YA 3S3QA 1CJLA 7PCKA 3IOQA 3GCBA 4CZWA 4X6HA 4QRVA 1U9WA 2IPPB 1ME3A 2F1GA 4DMXA 4G54A 2FYEA 3BCNA 1PIPA 1FH0A 1AYVA 1PADA 3RVVA 1AU3A 1MHWA 3V6EA 3BC3A 1THEA 2YJCA 2AYNA 1U5IA 1EWOA 1BQIA 2BDLA 2HXZA 3I06A 4HWYA 3K24A 2O6XA 2DC9A 3MTNA 4YYRA 1PXVA 4YYQA 2AS8A 3N3GA 1CPJA 3PBHA 2AUXA 3HHIA 1TU6A 2OULA 1PPOA 1ME4A 4ZUXU 3KWZA 4MZSA 1AU2A 2NQIA 5FPWA 3QT4A 4CDDB 1NLJA 1F2CA 5JA7A 1IWDA 4P6EA 2CB5A 1KHPA 2PREA 1MIRA 4Q8HA 5CVOB 1CV8A 1YT7A 1BGOA 3H89A 3K9MA 3IMAA 4QBBA 3H6SA 1QOLA 1K3BB 4P6GA 2P7UA 3KWBX 3U8EA 3BWKA 3KSEA 2ARYA 3HHAA 2NQGA 2XU4A 4W4UA 1DF0A 1CTEA 1AU0A 1PPNA 2JQFR 1GECE 1ATKA 2R9NA 2G6DA 3K8UA 1SNKA 3B79A 2Y6EA 1VSNA 2FRAA 2F7DA 3OVZA 1BP4A 3MHSA 4QRGA 3CH3X 1BY8A 4PADA 4PP1A 3H7DA 2ATOA 8PCHA 2WBFX 2IBIA 3P5XA 1Y4HA 5PADA 1GMYA 3V6CA 5F02A 1GLOA 1MS6A 2DJFB 3NHEA 4MZOA 2BDZA 3HD3A 5K16A 1ZCMA
chains in the Genus database with same CATH superfamily
2XU3A 4QRXA 3DF0A 1PCIA 3P5VA 4BOZA 2DJGB 4WA6A 3MHHA 4D8IA 2FRQA 3PSEA 4BQVA 1YVBA 2AYOA 4D8EA 1KXRA 1MDWA 3S3RA 3OISA 5EZQA 1EWPA 1EF7A 2C0YA 2BU3A 4DMYA 4YV8A 4YVAA 4AXLA 1S4VA 2DCBA 1F2AA 2OP3A 4OW0A 2DZYA 3H8CA 2FO5A 2HD5A 1O0EA 2B1MA 3F5VA 1STFE 1QXPA 4RY2A 2B1NA 1CSBB 1AIMA 3OF9A 3IFUA 2CIOA 1VJVA 5EZSA 3IEJA 2G8EA 3P5UA 4AXMA 1POPA 4X6JA 4R3DA 1CS8A 2OZ2A 4N8WA 4GUAA 2BTWA 2G8JA 3RVWA 3PRPA 2R9MA 4BS5A 1F2BA 1U9VA 3KFQA 4BOSA 2R9OA 3C9EA 4FJCA 3WXEA 2R9FA 2FTDA 1NB3A 4YYVA 2DOSA 2AVWA 5CVNB 2YJBA 2FUDA 1PE6A 1AYUA 2DCCA 4OEMA 3USVA 3P5WA 1PBHA 1Q6KA 3ERVA 2FT2A 5J94A 1U9XA 2NQAA 5A24A 1ICFA 2DCDA 1YALA 3F75A 3PNRA 3QSDA 1M6DA 1GCBA 4CDEB 4YYWA 5JZEA 4REZA 3WXGA 4PT5A 2G7YA 4CDCB 2FQ9A 2GFOA 1KFXL 1MEGA 4KLBA 1CQDA 3D6SA 2DCAA 3O65A 1A6RA 1HUCB 1AYWA 2YJ9A 2DZZA 4BOPA 3PHWA 3BBAA 1KHQA 4W5BA 2R9CA 3OVXA 1AU4A 3O0UA 3BPMA 1XKGA 4MSXA 2PADA 5CHVA 2AU1A 2P86A 1CVZA 2NQDB 4YYUA 2R6NA 3BPFA 3AI8A 2DC7A 5CHTA 3N3KA 4XR7A 5KO3A 4BOQA 2HH5A 4I07A 4IUMA 3IHPA 1AECA 2VHFA 6PADA 2E03A 2VHSA 2DC8A 4OVZB 1NB5A 2E02A 3IV2A 3KW9A 4QH6A 3E9SA 4RF0A 5EF4A 1YK7A 4FIPA 3WXFA 3ZUAA 4HXDB 2E01A 2PBHA 2AIMA 3TNXA 1SP4B 2E00A 4BPVA 2JRIA 3LXSA 3HWNA 4MM3B 1U9QX 2HHNA 3KX1A 3H8BA 1NQCA 3I3TA 1YZBA 4W5CA 1EWMA 1JQPA 3CH2X 4PI3A 2GHUA 1EWLA 4I04A 4X6IA 4CDFB 5CVMA 1QDQA 4N4ZA 3CBKA 3QJ3A 3CBJA 1DKIA 2AGAA 2DC6A 4Q8GA 3PW3A 3BOWA 3RNVA 1ITOA 4BS6A 4PP2E 1TLOA 1F29A 3KKUA 1TL9A 4YYSA 2ACTA 9PAPA 3B21A 3OF8A 4K7CA 2P0RA 1DEUA 4FK5A 2Y5BA 1YK8A 3O1GA 1NPZA 3LFYA 1PPPA 2PNSA 4D8BA 1MEMA 2BTWB 1KFUL 3E1ZB 2YJ2A 3M99A 1Y08A 1NL6A 2H7JA 5EGWA 2JQGR 3BY4A 3N4CA 1CB5A 3PDFA 3PRMA 4N79A 3RVXA 2XU5A 1QMYA 5JH3A 2YJ8A 3IUTA 2AUZA 3MORA 4OELA 1UKFA 1ZIVA 4XUIA 4BSQA 2XU1A 4XZXA 1PPDA 4I05A 1X9YA 3S3QA 1CJLA 7PCKA 3IOQA 3GCBA 4CZWA 4X6HA 4QRVA 1U9WA 2IPPB 1ME3A 2F1GA 4DMXA 4G54A 2FYEA 2J7QC 3BCNA 4RF1A 1PIPA 1FH0A 1AYVA 1PADA 3RVVA 1AU3A 1MHWA 3V6EA 3BC3A 4RKXA 5E6JA 1THEA 2YJCA 2AYNA 1U5IA 1EWOA 1BQIA 2BDLA 2HXZA 3I06A 4HWYA 3K24A 4RNAA 2O6XA 4A5UA 2DC9A 3MTNA 4YYRA 3W31A 1PXVA 4WURA 4YYQA 2JTCA 2AS8A 3N3GA 3C0RA 1CPJA 3PBHA 2AUXA 3HHIA 3ZNHA 1TU6A 2OULA 2UZJA 1PPOA 1ME4A 4ZUXU 3KWZA 4MZSA 1AU2A 2NQIA 5FPWA 3QT4A 4CDDB 1NLJA 1F2CA 5JA7A 1IWDA 4P6EA 2CB5A 1KHPA 2PREA 1MIRA 4Q8HA 3MP2A 5CVOB 1CV8A 1YT7A 4P16A 1BGOA 3H89A 3PHUA 2Z84A 3K9MA 3IMAA 4QBBA 3H6SA 1QOLA 1K3BB 4P6GA 2P7UA 3KWBX 3U8EA 2HWKA 3BWKA 3KSEA 2ARYA 3HHAA 2NQGA 2XU4A 4W4UA 1PVJA 3TMPA 1DF0A 1CTEA 1AU0A 4BOUA 1PPNA 2JQFR 4MI7A 4ZTBA 3BB7A 1GECE 3MTVA 1ATKA 2R9NA 2G6DA 3K8UA 1SNKA 3B79A 2Y6EA 1VSNA 2FRAA 2F7DA 3OVZA 1BP4A 4M0WA 3MHSA 4QRGA 3CH3X 1BY8A 4PADA 4PP1A 3H7DA 3TRKA 2ATOA 4IP3A 3OQCA 2FE8A 8PCHA 2WBFX 2IBIA 3PHXA 3P5XA 1Y4HA 3MJ5A 5PADA 1GMYA 2J7QA 3V6CA 5F02A 1GLOA 1MS6A 2DJFB 3NHEA 4MZOA 4OVZA 2BDZA 3W30A 3HD3A 3PT2A 5K16A 1ZCMA
chains in the Genus database with same CATH topology
2XU3A 4QRXA 3DF0A 1PCIA 3P5VA 2DJGB 4WA6A 3MHHA 2FRQA 4BQVA 1YVBA 2AYOA 1KXRA 1MDWA 3S3RA 3OISA 1EWPA 1EF7A 2C0YA 4DMYA 4YV8A 4YVAA 4AXLA 1S4VA 2DCBA 1F2AA 2OP3A 2DZYA 3H8CA 2FO5A 2HD5A 1O0EA 2B1MA 3F5VA 1STFE 1QXPA 4RY2A 2B1NA 1CSBB 1AIMA 3OF9A 2CIOA 1VJVA 3IEJA 2G8EA 3P5UA 4AXMA 1POPA 4X6JA 1CS8A 2OZ2A 4N8WA 2G8JA 3RVWA 2R9MA 4BS5A 1F2BA 1U9VA 3KFQA 4FJCA 2R9OA 3C9EA 3WXEA 2R9FA 2FTDA 1NB3A 4YYVA 2AVWA 5CVNB 2YJBA 2FUDA 1PE6A 1AYUA 2DCCA 4OEMA 3USVA 3P5WA 1PBHA 1Q6KA 3ERVA 2FT2A 5J94A 1U9XA 2NQAA 5A24A 1ICFA 2DCDA 1YALA 3F75A 3PNRA 3QSDA 1M6DA 1GCBA 4CDEB 4YYWA 3WXGA 2G7YA 4CDCB 2FQ9A 2GFOA 1KFXL 1MEGA 4KLBA 1CQDA 3D6SA 2DCAA 1A6RA 1HUCB 1AYWA 2YJ9A 2DZZA 2VFBA 1KHQA 4W5BA 2R9CA 3OVXA 1AU4A 3O0UA 3D9WA 3BPMA 1XKGA 4MSXA 2PADA 5CHVA 2AU1A 2P86A 1CVZA 2NQDB 4YYUA 2R6NA 3BPFA 3AI8A 2DC7A 5CHTA 3N3KA 4XR7A 4GUZA 2HH5A 4I07A 3IHPA 1AECA 2VHFA 6PADA 2E03A 2VHSA 2DC8A 1NB5A 2E02A 3IV2A 3KW9A 4QH6A 5EF4A 1YK7A 4FIPA 3WXFA 3ZUAA 4NV8A 2E01A 2PBHA 2AIMA 3TNXA 1SP4B 2E00A 4BPVA 1E2TA 3LXSA 3HWNA 1U9QX 2HHNA 3KX1A 3H8BA 1NQCA 3I3TA 4W5CA 1EWMA 1JQPA 3CH2X 4PI3A 2VFCA 2GHUA 1EWLA 4I04A 4X6IA 4CDFB 5CVMA 1QDQA 4N4ZA 3CBKA 3QJ3A 3CBJA 2DC6A 4Q8GA 1W4TA 3PW3A 3BOWA 1ITOA 4BS6A 4PP2E 1TLOA 1F29A 3KKUA 1TL9A 4YYSA 2ACTA 3LTWA 9PAPA 3OF8A 4K7CA 2P0RA 1DEUA 4FK5A 2Y5BA 1YK8A 3O1GA 1NPZA 3LFYA 1PPPA 2PNSA 1MEMA 1KFUL 3E1ZB 2YJ2A 3M99A 4B55A 1Y08A 1NL6A 2H7JA 5EGWA 2JQGR 3N4CA 1CB5A 3PDFA 4N79A 3RVXA 2XU5A 1QMYA 5JH3A 2YJ8A 3IUTA 2AUZA 3MORA 4OELA 1ZIVA 4XUIA 4BSQA 2XU1A 1PPDA 4I05A 1X9YA 3S3QA 1CJLA 7PCKA 3IOQA 3GCBA 4CZWA 4X6HA 4QRVA 1U9WA 2IPPB 1ME3A 2F1GA 4DMXA 4G54A 4NV7A 2FYEA 3BCNA 1PIPA 1FH0A 1AYVA 1PADA 3RVVA 1AU3A 1MHWA 3V6EA 3BC3A 1THEA 2YJCA 2AYNA 1U5IA 1EWOA 1BQIA 2BDLA 2HXZA 3I06A 4HWYA 3K24A 2O6XA 2DC9A 3MTNA 4YYRA 1PXVA 4YYQA 2AS8A 3N3GA 1CPJA 3PBHA 2AUXA 3HHIA 1TU6A 2OULA 1PPOA 1ME4A 4ZUXU 3KWZA 4MZSA 1AU2A 2NQIA 5FPWA 3QT4A 4CDDB 1NLJA 1F2CA 5JA7A 1IWDA 4P6EA 2CB5A 1KHPA 2PREA 1MIRA 4Q8HA 5CVOB 1CV8A 1YT7A 1BGOA 3H89A 3K9MA 3IMAA 4QBBA 3H6SA 4C5PA 1QOLA 1K3BB 4P6GA 2P7UA 3KWBX 3U8EA 1W5RA 3BWKA 3KSEA 2ARYA 3HHAA 2NQGA 2XU4A 4W4UA 1DF0A 1CTEA 1AU0A 1PPNA 2JQFR 1GECE 1ATKA 2R9NA 2G6DA 3K8UA 1W6FA 1SNKA 3B79A 2Y6EA 1VSNA 2FRAA 2F7DA 3OVZA 1BP4A 3MHSA 4QRGA 3CH3X 1BY8A 4PADA 4PP1A 3H7DA 2BSZA 1GX3A 2ATOA 8PCHA 2WBFX 2IBIA 3P5XA 1Y4HA 5PADA 1GMYA 3V6CA 5F02A 1GLOA 1MS6A 2DJFB 3NHEA 4MZOA 2BDZA 3HD3A 5K16A 4BGFA 1ZCMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XU3 A;  4QRX A;  3DF0 A;  1PCI A;  3P5V A;  2DJG B;  4WA6 A;  3MHH A;  2FRQ A;  4BQV A;  1YVB A;  2AYO A;  1KXR A;  1MDW A;  3S3R A;  3OIS A;  1EWP A;  1EF7 A;  2C0Y A;  4DMY A;  4YV8 A;  4YVA A;  4AXL A;  1S4V A;  2DCB A;  1F2A A;  2OP3 A;  2DZY A;  3H8C A;  2FO5 A;  2HD5 A;  1O0E A;  2B1M A;  3F5V A;  1STF E;  1QXP A;  4RY2 A;  2B1N A;  1CSB B;  1AIM A;  3OF9 A;  2CIO A;  1VJV A;  3IEJ A;  2G8E A;  3P5U A;  4AXM A;  1POP A;  4X6J A;  1CS8 A;  2OZ2 A;  4N8W A;  2G8J A;  3RVW A;  2R9M A;  4BS5 A;  1F2B A;  1U9V A;  3KFQ A;  4FJC A;  2R9O A;  3C9E A;  3WXE A;  2R9F A;  2FTD A;  1NB3 A;  4YYV A;  2AVW A;  5CVN B;  2YJB A;  2FUD A;  1PE6 A;  1AYU A;  2DCC A;  4OEM A;  3USV A;  3P5W A;  1PBH A;  1Q6K A;  3ERV A;  2FT2 A;  5J94 A;  1U9X A;  2NQA A;  5A24 A;  1ICF A;  2DCD A;  1YAL A;  3F75 A;  3PNR A;  3QSD A;  1M6D A;  1GCB A;  4CDE B;  4YYW A;  3WXG A;  2G7Y A;  4CDC B;  2FQ9 A;  2GFO A;  1KFX L;  1MEG A;  4KLB A;  1CQD A;  3D6S A;  2DCA A;  1A6R A;  1HUC B;  1AYW A;  2YJ9 A;  2DZZ A;  1KHQ A;  4W5B A;  2R9C A;  3OVX A;  1AU4 A;  3O0U A;  3BPM A;  1XKG A;  4MSX A;  2PAD A;  5CHV A;  2AU1 A;  2P86 A;  1CVZ A;  2NQD B;  4YYU A;  2R6N A;  3BPF A;  3AI8 A;  2DC7 A;  5CHT A;  3N3K A;  4XR7 A;  2HH5 A;  4I07 A;  3IHP A;  1AEC A;  2VHF A;  6PAD A;  2E03 A;  2VHS A;  2DC8 A;  1NB5 A;  2E02 A;  3IV2 A;  3KW9 A;  4QH6 A;  5EF4 A;  1YK7 A;  4FIP A;  3WXF A;  3ZUA A;  2E01 A;  2PBH A;  2AIM A;  3TNX A;  1SP4 B;  2E00 A;  4BPV A;  3LXS A;  3HWN A;  1U9Q X;  2HHN A;  3KX1 A;  3H8B A;  1NQC A;  3I3T A;  4W5C A;  1EWM A;  1JQP A;  3CH2 X;  4PI3 A;  2GHU A;  1EWL A;  4I04 A;  4X6I A;  4CDF B;  5CVM A;  1QDQ A;  4N4Z A;  3CBK A;  3QJ3 A;  3CBJ A;  2DC6 A;  4Q8G A;  3PW3 A;  3BOW A;  1ITO A;  4BS6 A;  4PP2 E;  1TLO A;  1F29 A;  3KKU A;  1TL9 A;  4YYS A;  2ACT A;  9PAP A;  3OF8 A;  4K7C A;  2P0R A;  1DEU A;  4FK5 A;  2Y5B A;  1YK8 A;  3O1G A;  1NPZ A;  3LFY A;  1PPP A;  2PNS A;  1MEM A;  1KFU L;  3E1Z B;  2YJ2 A;  3M99 A;  1Y08 A;  1NL6 A;  2H7J A;  5EGW A;  2JQG R;  3N4C A;  1CB5 A;  3PDF A;  4N79 A;  3RVX A;  2XU5 A;  1QMY A;  5JH3 A;  2YJ8 A;  3IUT A;  2AUZ A;  3MOR A;  4OEL A;  1ZIV A;  4XUI A;  4BSQ A;  2XU1 A;  1PPD A;  4I05 A;  1X9Y A;  3S3Q A;  1CJL A;  7PCK A;  3IOQ A;  3GCB A;  4CZW A;  4X6H A;  4QRV A;  1U9W A;  2IPP B;  1ME3 A;  2F1G A;  4DMX A;  4G54 A;  2FYE A;  3BCN A;  1PIP A;  1FH0 A;  1AYV A;  1PAD A;  3RVV A;  1AU3 A;  1MHW A;  3V6E A;  3BC3 A;  1THE A;  2YJC A;  2AYN A;  1U5I A;  1EWO A;  1BQI A;  2BDL A;  2HXZ A;  3I06 A;  4HWY A;  3K24 A;  2O6X A;  2DC9 A;  3MTN A;  4YYR A;  1PXV A;  4YYQ A;  2AS8 A;  3N3G A;  1CPJ A;  3PBH A;  2AUX A;  3HHI A;  1TU6 A;  2OUL A;  1PPO A;  1ME4 A;  4ZUX U;  3KWZ A;  4MZS A;  1AU2 A;  2NQI A;  5FPW A;  3QT4 A;  4CDD B;  1NLJ A;  1F2C A;  5JA7 A;  1IWD A;  4P6E A;  2CB5 A;  1KHP A;  2PRE A;  1MIR A;  4Q8H A;  5CVO B;  1CV8 A;  1YT7 A;  1BGO A;  3H89 A;  3K9M A;  3IMA A;  4QBB A;  3H6S A;  1QOL A;  1K3B B;  4P6G A;  2P7U A;  3KWB X;  3U8E A;  3BWK A;  3KSE A;  2ARY A;  3HHA A;  2NQG A;  2XU4 A;  4W4U A;  1DF0 A;  1CTE A;  1AU0 A;  1PPN A;  2JQF R;  1GEC E;  1ATK A;  2R9N A;  2G6D A;  3K8U A;  1SNK A;  3B79 A;  2Y6E A;  1VSN A;  2FRA A;  2F7D A;  3OVZ A;  1BP4 A;  3MHS A;  4QRG A;  3CH3 X;  1BY8 A;  4PAD A;  4PP1 A;  3H7D A;  2ATO A;  8PCH A;  2WBF X;  2IBI A;  3P5X A;  1Y4H A;  5PAD A;  1GMY A;  3V6C A;  5F02 A;  1GLO A;  1MS6 A;  2DJF B;  3NHE A;  4MZO A;  2BDZ A;  3HD3 A;  5K16 A;  1ZCM A; 
#chains in the Genus database with same CATH topology
 2XU3 A;  4QRX A;  3DF0 A;  1PCI A;  3P5V A;  4BOZ A;  2DJG B;  4WA6 A;  3MHH A;  4D8I A;  2FRQ A;  3PSE A;  4BQV A;  1YVB A;  2AYO A;  4D8E A;  1KXR A;  1MDW A;  3S3R A;  3OIS A;  5EZQ A;  1EWP A;  1EF7 A;  2C0Y A;  2BU3 A;  4DMY A;  4YV8 A;  4YVA A;  4AXL A;  1S4V A;  2DCB A;  1F2A A;  2OP3 A;  4OW0 A;  2DZY A;  3H8C A;  2FO5 A;  2HD5 A;  1O0E A;  2B1M A;  3F5V A;  1STF E;  1QXP A;  4RY2 A;  2B1N A;  1CSB B;  1AIM A;  3OF9 A;  3IFU A;  2CIO A;  1VJV A;  5EZS A;  3IEJ A;  2G8E A;  3P5U A;  4AXM A;  1POP A;  4X6J A;  4R3D A;  1CS8 A;  2OZ2 A;  4N8W A;  4GUA A;  2BTW A;  2G8J A;  3RVW A;  3PRP A;  2R9M A;  4BS5 A;  1F2B A;  1U9V A;  3KFQ A;  4BOS A;  2R9O A;  3C9E A;  4FJC A;  3WXE A;  2R9F A;  2FTD A;  1NB3 A;  4YYV A;  2DOS A;  2AVW A;  5CVN B;  2YJB A;  2FUD A;  1PE6 A;  1AYU A;  2DCC A;  4OEM A;  3USV A;  3P5W A;  1PBH A;  1Q6K A;  3ERV A;  2FT2 A;  5J94 A;  1U9X A;  2NQA A;  5A24 A;  1ICF A;  2DCD A;  1YAL A;  3F75 A;  3PNR A;  3QSD A;  1M6D A;  1GCB A;  4CDE B;  4YYW A;  5JZE A;  4REZ A;  3WXG A;  4PT5 A;  2G7Y A;  4CDC B;  2FQ9 A;  2GFO A;  1KFX L;  1MEG A;  4KLB A;  1CQD A;  3D6S A;  2DCA A;  3O65 A;  1A6R A;  1HUC B;  1AYW A;  2YJ9 A;  2DZZ A;  4BOP A;  3PHW A;  3BBA A;  1KHQ A;  4W5B A;  2R9C A;  3OVX A;  1AU4 A;  3O0U A;  3BPM A;  1XKG A;  4MSX A;  2PAD A;  5CHV A;  2AU1 A;  2P86 A;  1CVZ A;  2NQD B;  4YYU A;  2R6N A;  3BPF A;  3AI8 A;  2DC7 A;  5CHT A;  3N3K A;  4XR7 A;  5KO3 A;  4BOQ A;  2HH5 A;  4I07 A;  4IUM A;  3IHP A;  1AEC A;  2VHF A;  6PAD A;  2E03 A;  2VHS A;  2DC8 A;  4OVZ B;  1NB5 A;  2E02 A;  3IV2 A;  3KW9 A;  4QH6 A;  3E9S A;  4RF0 A;  5EF4 A;  1YK7 A;  4FIP A;  3WXF A;  3ZUA A;  4HXD B;  2E01 A;  2PBH A;  2AIM A;  3TNX A;  1SP4 B;  2E00 A;  4BPV A;  2JRI A;  3LXS A;  3HWN A;  4MM3 B;  1U9Q X;  2HHN A;  3KX1 A;  3H8B A;  1NQC A;  3I3T A;  1YZB A;  4W5C A;  1EWM A;  1JQP A;  3CH2 X;  4PI3 A;  2GHU A;  1EWL A;  4I04 A;  4X6I A;  4CDF B;  5CVM A;  1QDQ A;  4N4Z A;  3CBK A;  3QJ3 A;  3CBJ A;  1DKI A;  2AGA A;  2DC6 A;  4Q8G A;  3PW3 A;  3BOW A;  3RNV A;  1ITO A;  4BS6 A;  4PP2 E;  1TLO A;  1F29 A;  3KKU A;  1TL9 A;  4YYS A;  2ACT A;  9PAP A;  3B21 A;  3OF8 A;  4K7C A;  2P0R A;  1DEU A;  4FK5 A;  2Y5B A;  1YK8 A;  3O1G A;  1NPZ A;  3LFY A;  1PPP A;  2PNS A;  4D8B A;  1MEM A;  2BTW B;  1KFU L;  3E1Z B;  2YJ2 A;  3M99 A;  1Y08 A;  1NL6 A;  2H7J A;  5EGW A;  2JQG R;  3BY4 A;  3N4C A;  1CB5 A;  3PDF A;  3PRM A;  4N79 A;  3RVX A;  2XU5 A;  1QMY A;  5JH3 A;  2YJ8 A;  3IUT A;  2AUZ A;  3MOR A;  4OEL A;  1UKF A;  1ZIV A;  4XUI A;  4BSQ A;  2XU1 A;  4XZX A;  1PPD A;  4I05 A;  1X9Y A;  3S3Q A;  1CJL A;  7PCK A;  3IOQ A;  3GCB A;  4CZW A;  4X6H A;  4QRV A;  1U9W A;  2IPP B;  1ME3 A;  2F1G A;  4DMX A;  4G54 A;  2FYE A;  2J7Q C;  3BCN A;  4RF1 A;  1PIP A;  1FH0 A;  1AYV A;  1PAD A;  3RVV A;  1AU3 A;  1MHW A;  3V6E A;  3BC3 A;  4RKX A;  5E6J A;  1THE A;  2YJC A;  2AYN A;  1U5I A;  1EWO A;  1BQI A;  2BDL A;  2HXZ A;  3I06 A;  4HWY A;  3K24 A;  4RNA A;  2O6X A;  4A5U A;  2DC9 A;  3MTN A;  4YYR A;  3W31 A;  1PXV A;  4WUR A;  4YYQ A;  2JTC A;  2AS8 A;  3N3G A;  3C0R A;  1CPJ A;  3PBH A;  2AUX A;  3HHI A;  3ZNH A;  1TU6 A;  2OUL A;  2UZJ A;  1PPO A;  1ME4 A;  4ZUX U;  3KWZ A;  4MZS A;  1AU2 A;  2NQI A;  5FPW A;  3QT4 A;  4CDD B;  1NLJ A;  1F2C A;  5JA7 A;  1IWD A;  4P6E A;  2CB5 A;  1KHP A;  2PRE A;  1MIR A;  4Q8H A;  3MP2 A;  5CVO B;  1CV8 A;  1YT7 A;  4P16 A;  1BGO A;  3H89 A;  3PHU A;  2Z84 A;  3K9M A;  3IMA A;  4QBB A;  3H6S A;  1QOL A;  1K3B B;  4P6G A;  2P7U A;  3KWB X;  3U8E A;  2HWK A;  3BWK A;  3KSE A;  2ARY A;  3HHA A;  2NQG A;  2XU4 A;  4W4U A;  1PVJ A;  3TMP A;  1DF0 A;  1CTE A;  1AU0 A;  4BOU A;  1PPN A;  2JQF R;  4MI7 A;  4ZTB A;  3BB7 A;  1GEC E;  3MTV A;  1ATK A;  2R9N A;  2G6D A;  3K8U A;  1SNK A;  3B79 A;  2Y6E A;  1VSN A;  2FRA A;  2F7D A;  3OVZ A;  1BP4 A;  4M0W A;  3MHS A;  4QRG A;  3CH3 X;  1BY8 A;  4PAD A;  4PP1 A;  3H7D A;  3TRK A;  2ATO A;  4IP3 A;  3OQC A;  2FE8 A;  8PCH A;  2WBF X;  2IBI A;  3PHX A;  3P5X A;  1Y4H A;  3MJ5 A;  5PAD A;  1GMY A;  2J7Q A;  3V6C A;  5F02 A;  1GLO A;  1MS6 A;  2DJF B;  3NHE A;  4MZO A;  4OVZ A;  2BDZ A;  3W30 A;  3HD3 A;  3PT2 A;  5K16 A;  1ZCM A; 
#chains in the Genus database with same CATH homology
 2XU3 A;  4QRX A;  3DF0 A;  1PCI A;  3P5V A;  2DJG B;  4WA6 A;  3MHH A;  2FRQ A;  4BQV A;  1YVB A;  2AYO A;  1KXR A;  1MDW A;  3S3R A;  3OIS A;  1EWP A;  1EF7 A;  2C0Y A;  4DMY A;  4YV8 A;  4YVA A;  4AXL A;  1S4V A;  2DCB A;  1F2A A;  2OP3 A;  2DZY A;  3H8C A;  2FO5 A;  2HD5 A;  1O0E A;  2B1M A;  3F5V A;  1STF E;  1QXP A;  4RY2 A;  2B1N A;  1CSB B;  1AIM A;  3OF9 A;  2CIO A;  1VJV A;  3IEJ A;  2G8E A;  3P5U A;  4AXM A;  1POP A;  4X6J A;  1CS8 A;  2OZ2 A;  4N8W A;  2G8J A;  3RVW A;  2R9M A;  4BS5 A;  1F2B A;  1U9V A;  3KFQ A;  4FJC A;  2R9O A;  3C9E A;  3WXE A;  2R9F A;  2FTD A;  1NB3 A;  4YYV A;  2AVW A;  5CVN B;  2YJB A;  2FUD A;  1PE6 A;  1AYU A;  2DCC A;  4OEM A;  3USV A;  3P5W A;  1PBH A;  1Q6K A;  3ERV A;  2FT2 A;  5J94 A;  1U9X A;  2NQA A;  5A24 A;  1ICF A;  2DCD A;  1YAL A;  3F75 A;  3PNR A;  3QSD A;  1M6D A;  1GCB A;  4CDE B;  4YYW A;  3WXG A;  2G7Y A;  4CDC B;  2FQ9 A;  2GFO A;  1KFX L;  1MEG A;  4KLB A;  1CQD A;  3D6S A;  2DCA A;  1A6R A;  1HUC B;  1AYW A;  2YJ9 A;  2DZZ A;  2VFB A;  1KHQ A;  4W5B A;  2R9C A;  3OVX A;  1AU4 A;  3O0U A;  3D9W A;  3BPM A;  1XKG A;  4MSX A;  2PAD A;  5CHV A;  2AU1 A;  2P86 A;  1CVZ A;  2NQD B;  4YYU A;  2R6N A;  3BPF A;  3AI8 A;  2DC7 A;  5CHT A;  3N3K A;  4XR7 A;  4GUZ A;  2HH5 A;  4I07 A;  3IHP A;  1AEC A;  2VHF A;  6PAD A;  2E03 A;  2VHS A;  2DC8 A;  1NB5 A;  2E02 A;  3IV2 A;  3KW9 A;  4QH6 A;  5EF4 A;  1YK7 A;  4FIP A;  3WXF A;  3ZUA A;  4NV8 A;  2E01 A;  2PBH A;  2AIM A;  3TNX A;  1SP4 B;  2E00 A;  4BPV A;  1E2T A;  3LXS A;  3HWN A;  1U9Q X;  2HHN A;  3KX1 A;  3H8B A;  1NQC A;  3I3T A;  4W5C A;  1EWM A;  1JQP A;  3CH2 X;  4PI3 A;  2VFC A;  2GHU A;  1EWL A;  4I04 A;  4X6I A;  4CDF B;  5CVM A;  1QDQ A;  4N4Z A;  3CBK A;  3QJ3 A;  3CBJ A;  2DC6 A;  4Q8G A;  1W4T A;  3PW3 A;  3BOW A;  1ITO A;  4BS6 A;  4PP2 E;  1TLO A;  1F29 A;  3KKU A;  1TL9 A;  4YYS A;  2ACT A;  3LTW A;  9PAP A;  3OF8 A;  4K7C A;  2P0R A;  1DEU A;  4FK5 A;  2Y5B A;  1YK8 A;  3O1G A;  1NPZ A;  3LFY A;  1PPP A;  2PNS A;  1MEM A;  1KFU L;  3E1Z B;  2YJ2 A;  3M99 A;  4B55 A;  1Y08 A;  1NL6 A;  2H7J A;  5EGW A;  2JQG R;  3N4C A;  1CB5 A;  3PDF A;  4N79 A;  3RVX A;  2XU5 A;  1QMY A;  5JH3 A;  2YJ8 A;  3IUT A;  2AUZ A;  3MOR A;  4OEL A;  1ZIV A;  4XUI A;  4BSQ A;  2XU1 A;  1PPD A;  4I05 A;  1X9Y A;  3S3Q A;  1CJL A;  7PCK A;  3IOQ A;  3GCB A;  4CZW A;  4X6H A;  4QRV A;  1U9W A;  2IPP B;  1ME3 A;  2F1G A;  4DMX A;  4G54 A;  4NV7 A;  2FYE A;  3BCN A;  1PIP A;  1FH0 A;  1AYV A;  1PAD A;  3RVV A;  1AU3 A;  1MHW A;  3V6E A;  3BC3 A;  1THE A;  2YJC A;  2AYN A;  1U5I A;  1EWO A;  1BQI A;  2BDL A;  2HXZ A;  3I06 A;  4HWY A;  3K24 A;  2O6X A;  2DC9 A;  3MTN A;  4YYR A;  1PXV A;  4YYQ A;  2AS8 A;  3N3G A;  1CPJ A;  3PBH A;  2AUX A;  3HHI A;  1TU6 A;  2OUL A;  1PPO A;  1ME4 A;  4ZUX U;  3KWZ A;  4MZS A;  1AU2 A;  2NQI A;  5FPW A;  3QT4 A;  4CDD B;  1NLJ A;  1F2C A;  5JA7 A;  1IWD A;  4P6E A;  2CB5 A;  1KHP A;  2PRE A;  1MIR A;  4Q8H A;  5CVO B;  1CV8 A;  1YT7 A;  1BGO A;  3H89 A;  3K9M A;  3IMA A;  4QBB A;  3H6S A;  4C5P A;  1QOL A;  1K3B B;  4P6G A;  2P7U A;  3KWB X;  3U8E A;  1W5R A;  3BWK A;  3KSE A;  2ARY A;  3HHA A;  2NQG A;  2XU4 A;  4W4U A;  1DF0 A;  1CTE A;  1AU0 A;  1PPN A;  2JQF R;  1GEC E;  1ATK A;  2R9N A;  2G6D A;  3K8U A;  1W6F A;  1SNK A;  3B79 A;  2Y6E A;  1VSN A;  2FRA A;  2F7D A;  3OVZ A;  1BP4 A;  3MHS A;  4QRG A;  3CH3 X;  1BY8 A;  4PAD A;  4PP1 A;  3H7D A;  2BSZ A;  1GX3 A;  2ATO A;  8PCH A;  2WBF X;  2IBI A;  3P5X A;  1Y4H A;  5PAD A;  1GMY A;  3V6C A;  5F02 A;  1GLO A;  1MS6 A;  2DJF B;  3NHE A;  4MZO A;  2BDZ A;  3HD3 A;  5K16 A;  4BGF A;  1ZCM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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