2R9CA

Calpain 1 proteolytic core inactivated by zlak-3001, an alpha-ketoamide
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
322
structure length
322
Chain Sequence
NAIKYLGQDYENLRARCLQNGVLFQDDAFPPVSHSLGFKELGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNETILHRVVPYGQSFQEGYAGIFHFQLWQFGEWVDVVVDDLLPTKDGKLVFVHSAQGNEFWSALLEKAYAKVNGSYEALSGGCTSEAFEDFTGGVTEWYDLQKAPSDLYQIILKALERGSLLGCSINISDIRDLEAITFKNLVRGHAYSVTDAKQVTYQGQRVNLIRMRNPWGEVEWKGPWSDNSYEWNKVDPYEREQLRVKMEDGEFWMSFRDFIREFTKLEICNLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
pubmed doi rcsb
molecule tags Hydrolase
source organism Rattus norvegicus
molecule keywords Calpain-1 catalytic subunit
total genus 103
structure length 322
sequence length 322
ec nomenclature ec 3.4.22.52: Calpain-1.
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00648 Peptidase_C2 Calpain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2r9cA02
2XU3A 2BDLA 1ZIVA 2R9FA 5JH3A 3RVWA 4XUIA 1AYVA 1KFXL 1ITOA 2ATOA 2FO5A 3QJ3A 5F02A 1POPA 3H6SA 3RVXA 4BPVA 3WXGA 1PPPA 1PCIA 4N8WA 3CH3X 3BOWA 1YALA 3RVVA 1NB5A 2YJBA 1NLJA 3O1GA 3N4CA 1CTEA 2DC9A 4CDFB 2F7DA 4YYUA 2BDZA 2AUXA 1EWMA 3TNXA 3MHSA 3CBKA 3HWNA 3KWBX 4N79A 2FTDA 1AU0A 1IWDA 2AIMA 2E00A 2IPPB 2GHUA 1M6DA 4AXLA 1MEMA 2O6XA 4YYVA 4RY2A 1CVZA 1SP4B 4PADA 3ERVA 4XR7A 4YVAA 5FPWA 2G6DA 2YJ8A 1PADA 1YK7A 1XKGA 1EF7A 2G7YA 3ZUAA 1X9YA 4OELA 2AVWA 1QDQA 2JQFR 1GMYA 3KWZA 4QRXA 6PADA 4QRGA 1F29A 3HD3A 1U9QX 2DC7A 1U5IA 2FRAA 3KSEA 3KKUA 1GLOA 4HWYA 1THEA 1EWPA 1HUCB 5CVMA 5CHTA 3OF9A 1ZCMA 1DF0A 3BWKA 4DMYA 2R9CA 1STFE 2DZYA 3N3GA 3D6SA 3KFQA 1MHWA 1CV8A 1U9WA 3I3TA 2XU1A 3MHHA 3WXFA 2NQAA 2P0RA 2E03A 9PAPA 3PNRA 3S3QA 1MS6A 2R6NA 4MZSA 3P5XA 1QXPA 2G8EA 4FIPA 3KX1A 3IEJA 1Y08A 4CDEB 2NQGA 2OZ2A 2AS8A 3HHAA 3V6CA 3LXSA 3OVZA 4W5CA 4Q8GA 3KW9A 2C0YA 1GCBA 2AU1A 5EGWA 1U9VA 2CB5A 2PREA 1CJLA 2XU4A 3WXEA 1AYWA 4QH6A 2OP3A 1AU2A 5A24A 5CHVA 2FRQA 2CIOA 4I04A 2PADA 4DMXA 1GECE 3LFYA 1AIMA 2DCAA 2PBHA 1NPZA 3NHEA 3CH2X 3BPFA 3IMAA 3USVA 4N4ZA 1NB3A 3BCNA 1JQPA 1CPJA 3AI8A 2AYNA 1PXVA 4QRVA 1DEUA 2H7JA 1MEGA 1O0EA 3IUTA 2ARYA 7PCKA 1MIRA 5K16A 1A6RA 3E1ZB 3H89A 3P5UA 2E02A 2P86A 5JA7A 1ICFA 1CB5A 2DJFB 2DCDA 1PPNA 1AYUA 1VJVA 4P6GA 5J94A 4G54A 4P6EA 1BQIA 1PE6A 4YYSA 2R9NA 3U8EA 1BY8A 2YJ2A 2YJ9A 2DJGB 1Y4HA 3F75A 3O0UA 4PP2E 2P7UA 3V6EA 1ATKA 1F2AA 3GCBA 4BS6A 3PBHA 4YYRA 1F2BA 2DZZA 2FUDA 3N3KA 1CSBB 1S4VA 2G8JA 4BSQA 4FJCA 1CQDA 2FYEA 4MZOA 4FK5A 1CS8A 4CDCB 5CVNB 3P5VA 2HXZA 3S3RA 2R9OA 3H7DA 2VHFA 3K8UA 4YYQA 3QSDA 4BQVA 1EWOA 1KFUL 4K7CA 1NL6A 1TU6A 1PPOA 4I05A 3IHPA 4Q8HA 1ME3A 3OF8A 4YYWA 4X6HA 3IOQA 2GFOA 4PI3A 4MSXA 1KHQA 3F5VA 3IV2A 3OISA 2ACTA 5EF4A 4X6JA 4OEMA 4PP1A 3K24A 3QT4A 4QBBA 3MORA 4X6IA 1KHPA 3BPMA 2OULA 1VSNA 1EWLA 4W5BA 4ZUXU 2R9MA 2HH5A 2AUZA 2DC8A 3DF0A 4CDDB 1QOLA 1U9XA 1PBHA 3M99A 2FT2A 2HD5A 3C9EA 4KLBA 2B1MA 2IBIA 3B79A 3OVXA 1YT7A 1NQCA 1YVBA 1FH0A 2DC6A 3BC3A 1ME4A 1F2CA 1PPDA 2WBFX 1TLOA 2PNSA 2E01A 1K3BB 3PDFA 5PADA 4I07A 3P5WA 2B1NA 4BS5A 2XU5A 3H8CA 1QMYA 5CVOB 2VHSA 2F1GA 2HHNA 1AU3A 4AXMA 2DCCA 2AYOA 1BGOA 3I06A 3PW3A 1SNKA 3H8BA 1BP4A 1TL9A 2FQ9A 2Y6EA 4W4UA 1MDWA 1Q6KA 1AU4A 2NQIA 8PCHA 4CZWA 3K9MA 2JQGR 3MTNA 1KXRA 1AECA 2NQDB 2YJCA 2Y5BA 1YK8A 2DCBA 4YV8A 3CBJA 4WA6A 1PIPA 3HHIA
chains in the Genus database with same CATH superfamily
4GUAA 4HXDB 2XU3A 5E6JA 2BDLA 1ZIVA 2R9FA 5JH3A 2AGAA 3RVWA 4XUIA 1AYVA 1KFXL 1ITOA 2ATOA 2FO5A 3QJ3A 4BOUA 5F02A 1POPA 3H6SA 3RVXA 4BPVA 3WXGA 1PPPA 1PCIA 4N8WA 3CH3X 3BOWA 1YALA 3RVVA 1NB5A 2YJBA 4A5UA 1NLJA 3PHUA 2Z84A 3O1GA 5EZQA 3C0RA 3N4CA 1CTEA 2DC9A 4WURA 3W31A 4CDFB 2F7DA 4YYUA 2BDZA 2AUXA 4IP3A 1EWMA 3TNXA 3MHSA 3CBKA 4OVZA 3HWNA 3KWBX 4N79A 4PT5A 2FTDA 4BOZA 1AU0A 1IWDA 2BU3A 2AIMA 2E00A 2IPPB 2GHUA 1M6DA 3MTVA 5EZSA 4AXLA 4REZA 1MEMA 2O6XA 4IUMA 4YYVA 4RY2A 1CVZA 1SP4B 4PADA 3ERVA 4XR7A 4YVAA 5FPWA 2G6DA 2YJ8A 1PADA 1YK7A 1XKGA 1EF7A 2G7YA 3ZUAA 1X9YA 4MM3B 4OELA 2AVWA 1QDQA 2JQFR 1GMYA 3KWZA 4QRXA 6PADA 4QRGA 1F29A 3HD3A 1U9QX 4BOPA 2DC7A 3ZNHA 1U5IA 2FRAA 3KSEA 3KKUA 1GLOA 4P16A 4HWYA 1THEA 1EWPA 1HUCB 5CVMA 2BTWA 5CHTA 3OF9A 1ZCMA 1DF0A 3BWKA 4DMYA 2R9CA 1STFE 2DZYA 3N3GA 3D6SA 3KFQA 1MHWA 1CV8A 1U9WA 1UKFA 2XU1A 3I3TA 3MHHA 3WXFA 2NQAA 2P0RA 2E03A 9PAPA 2FE8A 3PNRA 3S3QA 1MS6A 2R6NA 4MZSA 3P5XA 4M0WA 1DKIA 1QXPA 2G8EA 4FIPA 3KX1A 3IEJA 1Y08A 4CDEB 2NQGA 2OZ2A 2AS8A 3HHAA 3V6CA 3LXSA 3OVZA 4W5CA 2J7QA 2JTCA 4Q8GA 3PHXA 1PVJA 3KW9A 2C0YA 1GCBA 2AU1A 5EGWA 1U9VA 2CB5A 2PREA 1CJLA 2XU4A 3WXEA 1AYWA 4QH6A 2OP3A 3IFUA 1AU2A 5A24A 5CHVA 2FRQA 3OQCA 2CIOA 3RNVA 4I04A 2PADA 5KO3A 4DMXA 1GECE 3LFYA 1AIMA 2DCAA 2PBHA 1NPZA 3NHEA 3CH2X 3BPFA 3IMAA 3USVA 4N4ZA 1NB3A 3BCNA 1JQPA 1CPJA 3AI8A 2AYNA 1PXVA 4QRVA 1DEUA 2H7JA 1MEGA 1O0EA 3IUTA 2ARYA 7PCKA 1MIRA 5K16A 1A6RA 3B21A 2DOSA 3E1ZB 3H89A 3P5UA 2E02A 2P86A 5JA7A 1ICFA 1CB5A 2DJFB 2DCDA 1PPNA 4OW0A 1AYUA 1VJVA 4P6GA 5J94A 4G54A 4P6EA 1BQIA 1PE6A 4D8BA 4YYSA 2R9NA 3U8EA 1BY8A 4R3DA 2YJ2A 4OVZB 2YJ9A 2DJGB 1Y4HA 5JZEA 3F75A 3O0UA 4PP2E 2P7UA 3V6EA 1ATKA 1F2AA 3GCBA 4BS6A 1YZBA 3PBHA 4YYRA 1F2BA 2DZZA 2FUDA 3N3KA 3MJ5A 1CSBB 1S4VA 2G8JA 4BSQA 3BY4A 4FJCA 1CQDA 2FYEA 2UZJA 4MZOA 3W30A 4FK5A 3O65A 1CS8A 4CDCB 5CVNB 3P5VA 2HXZA 4XZXA 3S3RA 2R9OA 3H7DA 2VHFA 3K8UA 3E9SA 3PRMA 4YYQA 3QSDA 4BQVA 1EWOA 1KFUL 4K7CA 1NL6A 1TU6A 2BTWB 1PPOA 4I05A 3IHPA 4Q8HA 1ME3A 3OF8A 4RNAA 4YYWA 2HWKA 4X6HA 3IOQA 2GFOA 4PI3A 4MSXA 1KHQA 4RF0A 3F5VA 3IV2A 3OISA 2ACTA 5EF4A 4X6JA 4OEMA 4PP1A 3K24A 3QT4A 4QBBA 3MORA 4X6IA 3TRKA 4RKXA 1KHPA 4BOSA 3BPMA 3PRPA 2OULA 3TMPA 1VSNA 1EWLA 3PHWA 4W5BA 4ZUXU 2R9MA 2HH5A 3MP2A 2AUZA 3PSEA 2DC8A 3DF0A 4CDDB 1QOLA 1U9XA 1PBHA 3M99A 2FT2A 2HD5A 3C9EA 4KLBA 2B1MA 2IBIA 4D8IA 3PT2A 3B79A 3OVXA 1YT7A 1NQCA 1YVBA 1FH0A 2DC6A 3BC3A 1ME4A 1F2CA 1PPDA 2WBFX 2JRIA 1TLOA 2PNSA 2E01A 1K3BB 3PDFA 5PADA 4I07A 4RF1A 3P5WA 2B1NA 4BS5A 3BB7A 2XU5A 3H8CA 1QMYA 5CVOB 2VHSA 2F1GA 2HHNA 1AU3A 4AXMA 2DCCA 3BBAA 2AYOA 1BGOA 3I06A 3PW3A 1SNKA 3H8BA 1BP4A 1TL9A 2FQ9A 2Y6EA 4W4UA 1MDWA 1Q6KA 1AU4A 2NQIA 8PCHA 4CZWA 4D8EA 3K9MA 2JQGR 3MTNA 4MI7A 1KXRA 1AECA 2NQDB 4ZTBA 2YJCA 2J7QC 2Y5BA 1YK8A 2DCBA 4BOQA 4YV8A 3CBJA 4WA6A 1PIPA 3HHIA
chains in the Genus database with same CATH topology
2XU3A 2BDLA 1ZIVA 2R9FA 5JH3A 3RVWA 4XUIA 1AYVA 1KFXL 1ITOA 2ATOA 2FO5A 3QJ3A 5F02A 1POPA 3H6SA 3RVXA 4NV8A 4BPVA 3WXGA 1PPPA 1PCIA 4N8WA 3CH3X 3BOWA 1YALA 3RVVA 1NB5A 2YJBA 1NLJA 3O1GA 3N4CA 1CTEA 2DC9A 4GUZA 4CDFB 2F7DA 4YYUA 2BDZA 2AUXA 1EWMA 3TNXA 3MHSA 3CBKA 3HWNA 3KWBX 4N79A 2FTDA 1GX3A 1AU0A 1IWDA 2AIMA 2E00A 2IPPB 2GHUA 1M6DA 4AXLA 1MEMA 2O6XA 4YYVA 4RY2A 1CVZA 1SP4B 4PADA 3ERVA 4XR7A 4YVAA 5FPWA 2G6DA 4B55A 2YJ8A 1PADA 2BSZA 1YK7A 1XKGA 1EF7A 2G7YA 3ZUAA 1X9YA 4OELA 2AVWA 1QDQA 2JQFR 1GMYA 3KWZA 4QRXA 6PADA 4QRGA 1F29A 3HD3A 1U9QX 2DC7A 1U5IA 2FRAA 3KSEA 3KKUA 1GLOA 4HWYA 1THEA 1EWPA 1HUCB 5CVMA 5CHTA 3OF9A 1ZCMA 1DF0A 3BWKA 4DMYA 2R9CA 1STFE 2DZYA 3N3GA 3D6SA 3KFQA 1MHWA 1CV8A 1U9WA 3I3TA 2XU1A 3MHHA 3WXFA 2NQAA 2P0RA 2E03A 9PAPA 3PNRA 3S3QA 1MS6A 2R6NA 4MZSA 3P5XA 1QXPA 2G8EA 4FIPA 3KX1A 3IEJA 1Y08A 4CDEB 2NQGA 2OZ2A 2AS8A 3HHAA 3V6CA 3LXSA 3OVZA 4W5CA 4Q8GA 3KW9A 2C0YA 1GCBA 2AU1A 5EGWA 1U9VA 2CB5A 2PREA 1CJLA 2XU4A 4C5PA 3WXEA 1AYWA 4QH6A 2OP3A 1AU2A 5A24A 5CHVA 2FRQA 2CIOA 4I04A 2PADA 4DMXA 1GECE 3LFYA 1AIMA 2DCAA 2PBHA 1NPZA 1W4TA 3CH2X 3NHEA 3BPFA 3IMAA 3USVA 4N4ZA 1NB3A 3BCNA 1JQPA 1CPJA 3AI8A 4NV7A 2AYNA 1PXVA 4QRVA 1DEUA 2H7JA 1MEGA 1O0EA 3IUTA 2ARYA 7PCKA 1MIRA 5K16A 1A6RA 3E1ZB 3H89A 3P5UA 2E02A 2P86A 5JA7A 1ICFA 1CB5A 2DJFB 2DCDA 1PPNA 1AYUA 1VJVA 4P6GA 5J94A 4G54A 4P6EA 1BQIA 1PE6A 4YYSA 2R9NA 3U8EA 1BY8A 2YJ2A 2YJ9A 2DJGB 1Y4HA 3F75A 3O0UA 4PP2E 2P7UA 3V6EA 1ATKA 1F2AA 3GCBA 4BS6A 3PBHA 4YYRA 1F2BA 2DZZA 2FUDA 3N3KA 1CSBB 1S4VA 2G8JA 4BSQA 4FJCA 1CQDA 2FYEA 4MZOA 4FK5A 1CS8A 4CDCB 5CVNB 3P5VA 2HXZA 3S3RA 2R9OA 3H7DA 2VHFA 3K8UA 4YYQA 3QSDA 4BQVA 1EWOA 1KFUL 4K7CA 1NL6A 3LTWA 1TU6A 1PPOA 4I05A 3IHPA 4Q8HA 1ME3A 3OF8A 4YYWA 4X6HA 3IOQA 2GFOA 4PI3A 2VFBA 4MSXA 1KHQA 3F5VA 3IV2A 3OISA 2ACTA 5EF4A 4X6JA 4OEMA 4PP1A 3K24A 3QT4A 4QBBA 3MORA 4X6IA 1KHPA 3BPMA 2OULA 1VSNA 1EWLA 4W5BA 4ZUXU 2R9MA 2HH5A 2AUZA 2DC8A 3DF0A 4CDDB 1QOLA 1U9XA 1PBHA 3M99A 2FT2A 2HD5A 3C9EA 4KLBA 2B1MA 2IBIA 3D9WA 3B79A 3OVXA 1YT7A 1NQCA 1W6FA 1FH0A 1YVBA 2DC6A 3BC3A 1ME4A 1F2CA 1PPDA 2WBFX 1TLOA 2PNSA 2VFCA 2E01A 1K3BB 3PDFA 5PADA 4I07A 3P5WA 2B1NA 4BS5A 2XU5A 3H8CA 1QMYA 5CVOB 2VHSA 2F1GA 2HHNA 1AU3A 4AXMA 2DCCA 1E2TA 2AYOA 1BGOA 3I06A 3PW3A 1SNKA 3H8BA 1BP4A 1TL9A 2FQ9A 2Y6EA 4W4UA 1MDWA 1Q6KA 1AU4A 2NQIA 8PCHA 4CZWA 3K9MA 2JQGR 3MTNA 1KXRA 1AECA 2NQDB 2YJCA 2Y5BA 1YK8A 2DCBA 4BGFA 4YV8A 3CBJA 4WA6A 1PIPA 3HHIA 1W5RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XU3 A;  2BDL A;  1ZIV A;  2R9F A;  5JH3 A;  3RVW A;  4XUI A;  1AYV A;  1KFX L;  1ITO A;  2ATO A;  2FO5 A;  3QJ3 A;  5F02 A;  1POP A;  3H6S A;  3RVX A;  4BPV A;  3WXG A;  1PPP A;  1PCI A;  4N8W A;  3CH3 X;  3BOW A;  1YAL A;  3RVV A;  1NB5 A;  2YJB A;  1NLJ A;  3O1G A;  3N4C A;  1CTE A;  2DC9 A;  4CDF B;  2F7D A;  4YYU A;  2BDZ A;  2AUX A;  1EWM A;  3TNX A;  3MHS A;  3CBK A;  3HWN A;  3KWB X;  4N79 A;  2FTD A;  1AU0 A;  1IWD A;  2AIM A;  2E00 A;  2IPP B;  2GHU A;  1M6D A;  4AXL A;  1MEM A;  2O6X A;  4YYV A;  4RY2 A;  1CVZ A;  1SP4 B;  4PAD A;  3ERV A;  4XR7 A;  4YVA A;  5FPW A;  2G6D A;  2YJ8 A;  1PAD A;  1YK7 A;  1XKG A;  1EF7 A;  2G7Y A;  3ZUA A;  1X9Y A;  4OEL A;  2AVW A;  1QDQ A;  2JQF R;  1GMY A;  3KWZ A;  4QRX A;  6PAD A;  4QRG A;  1F29 A;  3HD3 A;  1U9Q X;  2DC7 A;  1U5I A;  2FRA A;  3KSE A;  3KKU A;  1GLO A;  4HWY A;  1THE A;  1EWP A;  1HUC B;  5CVM A;  5CHT A;  3OF9 A;  1ZCM A;  1DF0 A;  3BWK A;  4DMY A;  2R9C A;  1STF E;  2DZY A;  3N3G A;  3D6S A;  3KFQ A;  1MHW A;  1CV8 A;  1U9W A;  3I3T A;  2XU1 A;  3MHH A;  3WXF A;  2NQA A;  2P0R A;  2E03 A;  9PAP A;  3PNR A;  3S3Q A;  1MS6 A;  2R6N A;  4MZS A;  3P5X A;  1QXP A;  2G8E A;  4FIP A;  3KX1 A;  3IEJ A;  1Y08 A;  4CDE B;  2NQG A;  2OZ2 A;  2AS8 A;  3HHA A;  3V6C A;  3LXS A;  3OVZ A;  4W5C A;  4Q8G A;  3KW9 A;  2C0Y A;  1GCB A;  2AU1 A;  5EGW A;  1U9V A;  2CB5 A;  2PRE A;  1CJL A;  2XU4 A;  3WXE A;  1AYW A;  4QH6 A;  2OP3 A;  1AU2 A;  5A24 A;  5CHV A;  2FRQ A;  2CIO A;  4I04 A;  2PAD A;  4DMX A;  1GEC E;  3LFY A;  1AIM A;  2DCA A;  2PBH A;  1NPZ A;  3NHE A;  3CH2 X;  3BPF A;  3IMA A;  3USV A;  4N4Z A;  1NB3 A;  3BCN A;  1JQP A;  1CPJ A;  3AI8 A;  2AYN A;  1PXV A;  4QRV A;  1DEU A;  2H7J A;  1MEG A;  1O0E A;  3IUT A;  2ARY A;  7PCK A;  1MIR A;  5K16 A;  1A6R A;  3E1Z B;  3H89 A;  3P5U A;  2E02 A;  2P86 A;  5JA7 A;  1ICF A;  1CB5 A;  2DJF B;  2DCD A;  1PPN A;  1AYU A;  1VJV A;  4P6G A;  5J94 A;  4G54 A;  4P6E A;  1BQI A;  1PE6 A;  4YYS A;  2R9N A;  3U8E A;  1BY8 A;  2YJ2 A;  2YJ9 A;  2DJG B;  1Y4H A;  3F75 A;  3O0U A;  4PP2 E;  2P7U A;  3V6E A;  1ATK A;  1F2A A;  3GCB A;  4BS6 A;  3PBH A;  4YYR A;  1F2B A;  2DZZ A;  2FUD A;  3N3K A;  1CSB B;  1S4V A;  2G8J A;  4BSQ A;  4FJC A;  1CQD A;  2FYE A;  4MZO A;  4FK5 A;  1CS8 A;  4CDC B;  5CVN B;  3P5V A;  2HXZ A;  3S3R A;  2R9O A;  3H7D A;  2VHF A;  3K8U A;  4YYQ A;  3QSD A;  4BQV A;  1EWO A;  1KFU L;  4K7C A;  1NL6 A;  1TU6 A;  1PPO A;  4I05 A;  3IHP A;  4Q8H A;  1ME3 A;  3OF8 A;  4YYW A;  4X6H A;  3IOQ A;  2GFO A;  4PI3 A;  4MSX A;  1KHQ A;  3F5V A;  3IV2 A;  3OIS A;  2ACT A;  5EF4 A;  4X6J A;  4OEM A;  4PP1 A;  3K24 A;  3QT4 A;  4QBB A;  3MOR A;  4X6I A;  1KHP A;  3BPM A;  2OUL A;  1VSN A;  1EWL A;  4W5B A;  4ZUX U;  2R9M A;  2HH5 A;  2AUZ A;  2DC8 A;  3DF0 A;  4CDD B;  1QOL A;  1U9X A;  1PBH A;  3M99 A;  2FT2 A;  2HD5 A;  3C9E A;  4KLB A;  2B1M A;  2IBI A;  3B79 A;  3OVX A;  1YT7 A;  1NQC A;  1YVB A;  1FH0 A;  2DC6 A;  3BC3 A;  1ME4 A;  1F2C A;  1PPD A;  2WBF X;  1TLO A;  2PNS A;  2E01 A;  1K3B B;  3PDF A;  5PAD A;  4I07 A;  3P5W A;  2B1N A;  4BS5 A;  2XU5 A;  3H8C A;  1QMY A;  5CVO B;  2VHS A;  2F1G A;  2HHN A;  1AU3 A;  4AXM A;  2DCC A;  2AYO A;  1BGO A;  3I06 A;  3PW3 A;  1SNK A;  3H8B A;  1BP4 A;  1TL9 A;  2FQ9 A;  2Y6E A;  4W4U A;  1MDW A;  1Q6K A;  1AU4 A;  2NQI A;  8PCH A;  4CZW A;  3K9M A;  2JQG R;  3MTN A;  1KXR A;  1AEC A;  2NQD B;  2YJC A;  2Y5B A;  1YK8 A;  2DCB A;  4YV8 A;  3CBJ A;  4WA6 A;  1PIP A;  3HHI A; 
#chains in the Genus database with same CATH topology
 4GUA A;  4HXD B;  2XU3 A;  5E6J A;  2BDL A;  1ZIV A;  2R9F A;  5JH3 A;  2AGA A;  3RVW A;  4XUI A;  1AYV A;  1KFX L;  1ITO A;  2ATO A;  2FO5 A;  3QJ3 A;  4BOU A;  5F02 A;  1POP A;  3H6S A;  3RVX A;  4BPV A;  3WXG A;  1PPP A;  1PCI A;  4N8W A;  3CH3 X;  3BOW A;  1YAL A;  3RVV A;  1NB5 A;  2YJB A;  4A5U A;  1NLJ A;  3PHU A;  2Z84 A;  3O1G A;  5EZQ A;  3C0R A;  3N4C A;  1CTE A;  2DC9 A;  4WUR A;  3W31 A;  4CDF B;  2F7D A;  4YYU A;  2BDZ A;  2AUX A;  4IP3 A;  1EWM A;  3TNX A;  3MHS A;  3CBK A;  4OVZ A;  3HWN A;  3KWB X;  4N79 A;  4PT5 A;  2FTD A;  4BOZ A;  1AU0 A;  1IWD A;  2BU3 A;  2AIM A;  2E00 A;  2IPP B;  2GHU A;  1M6D A;  3MTV A;  5EZS A;  4AXL A;  4REZ A;  1MEM A;  2O6X A;  4IUM A;  4YYV A;  4RY2 A;  1CVZ A;  1SP4 B;  4PAD A;  3ERV A;  4XR7 A;  4YVA A;  5FPW A;  2G6D A;  2YJ8 A;  1PAD A;  1YK7 A;  1XKG A;  1EF7 A;  2G7Y A;  3ZUA A;  1X9Y A;  4MM3 B;  4OEL A;  2AVW A;  1QDQ A;  2JQF R;  1GMY A;  3KWZ A;  4QRX A;  6PAD A;  4QRG A;  1F29 A;  3HD3 A;  1U9Q X;  4BOP A;  2DC7 A;  3ZNH A;  1U5I A;  2FRA A;  3KSE A;  3KKU A;  1GLO A;  4P16 A;  4HWY A;  1THE A;  1EWP A;  1HUC B;  5CVM A;  2BTW A;  5CHT A;  3OF9 A;  1ZCM A;  1DF0 A;  3BWK A;  4DMY A;  2R9C A;  1STF E;  2DZY A;  3N3G A;  3D6S A;  3KFQ A;  1MHW A;  1CV8 A;  1U9W A;  1UKF A;  2XU1 A;  3I3T A;  3MHH A;  3WXF A;  2NQA A;  2P0R A;  2E03 A;  9PAP A;  2FE8 A;  3PNR A;  3S3Q A;  1MS6 A;  2R6N A;  4MZS A;  3P5X A;  4M0W A;  1DKI A;  1QXP A;  2G8E A;  4FIP A;  3KX1 A;  3IEJ A;  1Y08 A;  4CDE B;  2NQG A;  2OZ2 A;  2AS8 A;  3HHA A;  3V6C A;  3LXS A;  3OVZ A;  4W5C A;  2J7Q A;  2JTC A;  4Q8G A;  3PHX A;  1PVJ A;  3KW9 A;  2C0Y A;  1GCB A;  2AU1 A;  5EGW A;  1U9V A;  2CB5 A;  2PRE A;  1CJL A;  2XU4 A;  3WXE A;  1AYW A;  4QH6 A;  2OP3 A;  3IFU A;  1AU2 A;  5A24 A;  5CHV A;  2FRQ A;  3OQC A;  2CIO A;  3RNV A;  4I04 A;  2PAD A;  5KO3 A;  4DMX A;  1GEC E;  3LFY A;  1AIM A;  2DCA A;  2PBH A;  1NPZ A;  3NHE A;  3CH2 X;  3BPF A;  3IMA A;  3USV A;  4N4Z A;  1NB3 A;  3BCN A;  1JQP A;  1CPJ A;  3AI8 A;  2AYN A;  1PXV A;  4QRV A;  1DEU A;  2H7J A;  1MEG A;  1O0E A;  3IUT A;  2ARY A;  7PCK A;  1MIR A;  5K16 A;  1A6R A;  3B21 A;  2DOS A;  3E1Z B;  3H89 A;  3P5U A;  2E02 A;  2P86 A;  5JA7 A;  1ICF A;  1CB5 A;  2DJF B;  2DCD A;  1PPN A;  4OW0 A;  1AYU A;  1VJV A;  4P6G A;  5J94 A;  4G54 A;  4P6E A;  1BQI A;  1PE6 A;  4D8B A;  4YYS A;  2R9N A;  3U8E A;  1BY8 A;  4R3D A;  2YJ2 A;  4OVZ B;  2YJ9 A;  2DJG B;  1Y4H A;  5JZE A;  3F75 A;  3O0U A;  4PP2 E;  2P7U A;  3V6E A;  1ATK A;  1F2A A;  3GCB A;  4BS6 A;  1YZB A;  3PBH A;  4YYR A;  1F2B A;  2DZZ A;  2FUD A;  3N3K A;  3MJ5 A;  1CSB B;  1S4V A;  2G8J A;  4BSQ A;  3BY4 A;  4FJC A;  1CQD A;  2FYE A;  2UZJ A;  4MZO A;  3W30 A;  4FK5 A;  3O65 A;  1CS8 A;  4CDC B;  5CVN B;  3P5V A;  2HXZ A;  4XZX A;  3S3R A;  2R9O A;  3H7D A;  2VHF A;  3K8U A;  3E9S A;  3PRM A;  4YYQ A;  3QSD A;  4BQV A;  1EWO A;  1KFU L;  4K7C A;  1NL6 A;  1TU6 A;  2BTW B;  1PPO A;  4I05 A;  3IHP A;  4Q8H A;  1ME3 A;  3OF8 A;  4RNA A;  4YYW A;  2HWK A;  4X6H A;  3IOQ A;  2GFO A;  4PI3 A;  4MSX A;  1KHQ A;  4RF0 A;  3F5V A;  3IV2 A;  3OIS A;  2ACT A;  5EF4 A;  4X6J A;  4OEM A;  4PP1 A;  3K24 A;  3QT4 A;  4QBB A;  3MOR A;  4X6I A;  3TRK A;  4RKX A;  1KHP A;  4BOS A;  3BPM A;  3PRP A;  2OUL A;  3TMP A;  1VSN A;  1EWL A;  3PHW A;  4W5B A;  4ZUX U;  2R9M A;  2HH5 A;  3MP2 A;  2AUZ A;  3PSE A;  2DC8 A;  3DF0 A;  4CDD B;  1QOL A;  1U9X A;  1PBH A;  3M99 A;  2FT2 A;  2HD5 A;  3C9E A;  4KLB A;  2B1M A;  2IBI A;  4D8I A;  3PT2 A;  3B79 A;  3OVX A;  1YT7 A;  1NQC A;  1YVB A;  1FH0 A;  2DC6 A;  3BC3 A;  1ME4 A;  1F2C A;  1PPD A;  2WBF X;  2JRI A;  1TLO A;  2PNS A;  2E01 A;  1K3B B;  3PDF A;  5PAD A;  4I07 A;  4RF1 A;  3P5W A;  2B1N A;  4BS5 A;  3BB7 A;  2XU5 A;  3H8C A;  1QMY A;  5CVO B;  2VHS A;  2F1G A;  2HHN A;  1AU3 A;  4AXM A;  2DCC A;  3BBA A;  2AYO A;  1BGO A;  3I06 A;  3PW3 A;  1SNK A;  3H8B A;  1BP4 A;  1TL9 A;  2FQ9 A;  2Y6E A;  4W4U A;  1MDW A;  1Q6K A;  1AU4 A;  2NQI A;  8PCH A;  4CZW A;  4D8E A;  3K9M A;  2JQG R;  3MTN A;  4MI7 A;  1KXR A;  1AEC A;  2NQD B;  4ZTB A;  2YJC A;  2J7Q C;  2Y5B A;  1YK8 A;  2DCB A;  4BOQ A;  4YV8 A;  3CBJ A;  4WA6 A;  1PIP A;  3HHI A; 
#chains in the Genus database with same CATH homology
 2XU3 A;  2BDL A;  1ZIV A;  2R9F A;  5JH3 A;  3RVW A;  4XUI A;  1AYV A;  1KFX L;  1ITO A;  2ATO A;  2FO5 A;  3QJ3 A;  5F02 A;  1POP A;  3H6S A;  3RVX A;  4NV8 A;  4BPV A;  3WXG A;  1PPP A;  1PCI A;  4N8W A;  3CH3 X;  3BOW A;  1YAL A;  3RVV A;  1NB5 A;  2YJB A;  1NLJ A;  3O1G A;  3N4C A;  1CTE A;  2DC9 A;  4GUZ A;  4CDF B;  2F7D A;  4YYU A;  2BDZ A;  2AUX A;  1EWM A;  3TNX A;  3MHS A;  3CBK A;  3HWN A;  3KWB X;  4N79 A;  2FTD A;  1GX3 A;  1AU0 A;  1IWD A;  2AIM A;  2E00 A;  2IPP B;  2GHU A;  1M6D A;  4AXL A;  1MEM A;  2O6X A;  4YYV A;  4RY2 A;  1CVZ A;  1SP4 B;  4PAD A;  3ERV A;  4XR7 A;  4YVA A;  5FPW A;  2G6D A;  4B55 A;  2YJ8 A;  1PAD A;  2BSZ A;  1YK7 A;  1XKG A;  1EF7 A;  2G7Y A;  3ZUA A;  1X9Y A;  4OEL A;  2AVW A;  1QDQ A;  2JQF R;  1GMY A;  3KWZ A;  4QRX A;  6PAD A;  4QRG A;  1F29 A;  3HD3 A;  1U9Q X;  2DC7 A;  1U5I A;  2FRA A;  3KSE A;  3KKU A;  1GLO A;  4HWY A;  1THE A;  1EWP A;  1HUC B;  5CVM A;  5CHT A;  3OF9 A;  1ZCM A;  1DF0 A;  3BWK A;  4DMY A;  2R9C A;  1STF E;  2DZY A;  3N3G A;  3D6S A;  3KFQ A;  1MHW A;  1CV8 A;  1U9W A;  3I3T A;  2XU1 A;  3MHH A;  3WXF A;  2NQA A;  2P0R A;  2E03 A;  9PAP A;  3PNR A;  3S3Q A;  1MS6 A;  2R6N A;  4MZS A;  3P5X A;  1QXP A;  2G8E A;  4FIP A;  3KX1 A;  3IEJ A;  1Y08 A;  4CDE B;  2NQG A;  2OZ2 A;  2AS8 A;  3HHA A;  3V6C A;  3LXS A;  3OVZ A;  4W5C A;  4Q8G A;  3KW9 A;  2C0Y A;  1GCB A;  2AU1 A;  5EGW A;  1U9V A;  2CB5 A;  2PRE A;  1CJL A;  2XU4 A;  4C5P A;  3WXE A;  1AYW A;  4QH6 A;  2OP3 A;  1AU2 A;  5A24 A;  5CHV A;  2FRQ A;  2CIO A;  4I04 A;  2PAD A;  4DMX A;  1GEC E;  3LFY A;  1AIM A;  2DCA A;  2PBH A;  1NPZ A;  1W4T A;  3CH2 X;  3NHE A;  3BPF A;  3IMA A;  3USV A;  4N4Z A;  1NB3 A;  3BCN A;  1JQP A;  1CPJ A;  3AI8 A;  4NV7 A;  2AYN A;  1PXV A;  4QRV A;  1DEU A;  2H7J A;  1MEG A;  1O0E A;  3IUT A;  2ARY A;  7PCK A;  1MIR A;  5K16 A;  1A6R A;  3E1Z B;  3H89 A;  3P5U A;  2E02 A;  2P86 A;  5JA7 A;  1ICF A;  1CB5 A;  2DJF B;  2DCD A;  1PPN A;  1AYU A;  1VJV A;  4P6G A;  5J94 A;  4G54 A;  4P6E A;  1BQI A;  1PE6 A;  4YYS A;  2R9N A;  3U8E A;  1BY8 A;  2YJ2 A;  2YJ9 A;  2DJG B;  1Y4H A;  3F75 A;  3O0U A;  4PP2 E;  2P7U A;  3V6E A;  1ATK A;  1F2A A;  3GCB A;  4BS6 A;  3PBH A;  4YYR A;  1F2B A;  2DZZ A;  2FUD A;  3N3K A;  1CSB B;  1S4V A;  2G8J A;  4BSQ A;  4FJC A;  1CQD A;  2FYE A;  4MZO A;  4FK5 A;  1CS8 A;  4CDC B;  5CVN B;  3P5V A;  2HXZ A;  3S3R A;  2R9O A;  3H7D A;  2VHF A;  3K8U A;  4YYQ A;  3QSD A;  4BQV A;  1EWO A;  1KFU L;  4K7C A;  1NL6 A;  3LTW A;  1TU6 A;  1PPO A;  4I05 A;  3IHP A;  4Q8H A;  1ME3 A;  3OF8 A;  4YYW A;  4X6H A;  3IOQ A;  2GFO A;  4PI3 A;  2VFB A;  4MSX A;  1KHQ A;  3F5V A;  3IV2 A;  3OIS A;  2ACT A;  5EF4 A;  4X6J A;  4OEM A;  4PP1 A;  3K24 A;  3QT4 A;  4QBB A;  3MOR A;  4X6I A;  1KHP A;  3BPM A;  2OUL A;  1VSN A;  1EWL A;  4W5B A;  4ZUX U;  2R9M A;  2HH5 A;  2AUZ A;  2DC8 A;  3DF0 A;  4CDD B;  1QOL A;  1U9X A;  1PBH A;  3M99 A;  2FT2 A;  2HD5 A;  3C9E A;  4KLB A;  2B1M A;  2IBI A;  3D9W A;  3B79 A;  3OVX A;  1YT7 A;  1NQC A;  1W6F A;  1FH0 A;  1YVB A;  2DC6 A;  3BC3 A;  1ME4 A;  1F2C A;  1PPD A;  2WBF X;  1TLO A;  2PNS A;  2VFC A;  2E01 A;  1K3B B;  3PDF A;  5PAD A;  4I07 A;  3P5W A;  2B1N A;  4BS5 A;  2XU5 A;  3H8C A;  1QMY A;  5CVO B;  2VHS A;  2F1G A;  2HHN A;  1AU3 A;  4AXM A;  2DCC A;  1E2T A;  2AYO A;  1BGO A;  3I06 A;  3PW3 A;  1SNK A;  3H8B A;  1BP4 A;  1TL9 A;  2FQ9 A;  2Y6E A;  4W4U A;  1MDW A;  1Q6K A;  1AU4 A;  2NQI A;  8PCH A;  4CZW A;  3K9M A;  2JQG R;  3MTN A;  1KXR A;  1AEC A;  2NQD B;  2YJC A;  2Y5B A;  1YK8 A;  2DCB A;  4BGF A;  4YV8 A;  3CBJ A;  4WA6 A;  1PIP A;  3HHI A;  1W5R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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