2VHFA

Structure of the cyld usp domain
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
374
structure length
341
Chain Sequence
GLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMAGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The Structure of the Cyld Usp Domain Explains its Specificity for Lys63-Linked Polyubiquitin and Reveals a B-Box Module
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD
total genus 85
structure length 341
sequence length 374
chains with identical sequence B
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2007-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00443 UCH Ubiquitin carboxyl-terminal hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2vhfA00
3RVVA 2E02A 3KFQA 3IUTA 3BC3A 3HHIA 1EWMA 2R9CA 4I05A 4XR7A 1PIPA 4CDEB 4I07A 3IV2A 2C0YA 2OULA 3U8EA 4QRVA 1U9QX 4YYQA 2E00A 3LXSA 3USVA 3WXFA 4CZWA 1NL6A 1A6RA 2DC7A 4CDCB 1VSNA 3H89A 1YVBA 3DF0A 2DCDA 3E1ZB 5CHVA 2R9FA 2WBFX 1QMYA 4RY2A 3HHAA 5A24A 4BS6A 3OVZA 3NHEA 1PPDA 4FIPA 4I04A 3IEJA 3RVXA 2F1GA 8PCHA 1M6DA 1POPA 1MHWA 1MS6A 2YJ9A 5PADA 3H6SA 3KSEA 4N79A 3C9EA 1F29A 3O1GA 4Q8HA 3RVWA 1YALA 4PP1A 3LFYA 5F02A 4QH6A 5EF4A 3QSDA 3F5VA 1PPPA 2FT2A 2CB5A 1K3BB 3P5WA 1EWLA 4PADA 1MDWA 3V6EA 2ATOA 1GCBA 3K8UA 3AI8A 3K9MA 2JQFR 4BSQA 1QXPA 2B1NA 1NB3A 1PBHA 2YJBA 2FTDA 1F2AA 1STFE 2FYEA 2GFOA 1AYWA 3PNRA 3S3RA 1GMYA 4KLBA 3N3KA 2IBIA 1GECE 5CVNB 4N8WA 1QDQA 4YVAA 4BS5A 3GCBA 2P0RA 4DMYA 1AIMA 1VJVA 4YYSA 7PCKA 3KKUA 3TNXA 2OZ2A 2FQ9A 3MTNA 2P86A 2XU4A 1Y08A 3PW3A 1BGOA 1FH0A 1IWDA 3OF8A 1CB5A 3QJ3A 5CVMA 3PBHA 1YT7A 1BP4A 1KHQA 2HHNA 3BCNA 3KW9A 2G7YA 3WXEA 4FJCA 2DCBA 5K16A 4AXLA 1CS8A 1EWOA 4OELA 4FK5A 4QRXA 2NQIA 1SNKA 2VHSA 3WXGA 1ATKA 3O0UA 2Y5BA 3D6SA 2ACTA 1TU6A 1TL9A 3BWKA 3P5VA 2NQAA 2CIOA 2R6NA 2HH5A 5FPWA 1CPJA 4X6IA 3CBJA 1ME4A 3OVXA 2FRQA 4BQVA 1KXRA 1MEMA 4PI3A 2Y6EA 3ERVA 5EGWA 4XUIA 1CQDA 2P7UA 2DC6A 4YYUA 2HXZA 1ZIVA 2FUDA 4CDDB 2DC8A 1MEGA 3KWBX 3N4CA 4P6GA 1GLOA 2PNSA 4K7CA 1NPZA 4MZSA 1NLJA 1ITOA 4G54A 1YK7A 5CVOB 1SP4B 3H8CA 2VHFA 3IMAA 1F2CA 1PXVA 2O6XA 3M99A 4HWYA 2R9OA 1HUCB 2AS8A 1JQPA 1KFUL 3KX1A 2DJGB 2YJCA 2XU5A 2AYOA 3P5UA 1AU2A 3N3GA 3I3TA 4QBBA 3ZUAA 1S4VA 2B1MA 1PE6A 2G8JA 4YV8A 3IOQA 1KHPA 1CVZA 1PADA 2FO5A 3BOWA 3P5XA 4MSXA 1BQIA 2R9NA 4ZUXU 4BPVA 1XKGA 2DC9A 3IHPA 3H7DA 1AU4A 1AU0A 2XU3A 2H7JA 3K24A 1TLOA 3F75A 2BDZA 1DEUA 2PBHA 3MHHA 2FRAA 2AUZA 1ICFA 2PREA 4YYRA 1U5IA 2GHUA 3HD3A 3HWNA 2AUXA 2AVWA 1U9WA 5JH3A 1Q6KA 4YYVA 5J94A 2DJFB 1KFXL 3KWZA 4PP2E 1QOLA 2NQGA 1CJLA 2YJ2A 3S3QA 2AIMA 2BDLA 3V6CA 2JQGR 1YK8A 2DZZA 2ARYA 4YYWA 2E03A 2G6DA 1AECA 2AU1A 2G8EA 1U9XA 2XU1A 4CDFB 1DF0A 1PPOA 1AYVA 1X9YA 1NQCA 3MORA 4W5CA 4W5BA 4X6JA 3PDFA 3CH3X 2HD5A 1THEA 3CBKA 3OISA 2OP3A 3BPMA 3QT4A 4P6EA 1MIRA 3CH2X 2DZYA 4QRGA 4DMXA 2DCCA 4Q8GA 1EF7A 4N4ZA 1ME3A 1ZCMA 1AYUA 1F2BA 1PPNA 1NB5A 3I06A 2NQDB 2PADA 4W4UA 4MZOA 4WA6A 1PCIA 2R9MA 1CSBB 4X6HA 2AYNA 4OEMA 1AU3A 1EWPA 3H8BA 3BPFA 2E01A 2DCAA 9PAPA 1Y4HA 6PADA 1O0EA 3OF9A 2YJ8A 5JA7A 3MHSA 2F7DA 1BY8A 2IPPB 5CHTA 4AXMA 1CTEA 1U9VA 3B79A 1CV8A
chains in the Genus database with same CATH superfamily
4XZXA 3RVVA 2E02A 3BB7A 3KFQA 4ZTBA 3IUTA 4BOUA 3BC3A 4IP3A 3HHIA 4A5UA 1EWMA 2R9CA 3PHUA 4I05A 4XR7A 1PIPA 4CDEB 3IFUA 4I07A 2J7QA 3IV2A 2C0YA 2OULA 3U8EA 4QRVA 1U9QX 4YYQA 2E00A 3LXSA 3USVA 3WXFA 4CZWA 1NL6A 1A6RA 2DC7A 4CDCB 1VSNA 3H89A 1YVBA 3DF0A 2DCDA 3E1ZB 5CHVA 3W31A 2R9FA 2WBFX 1QMYA 4GUAA 4RY2A 3HHAA 4REZA 5A24A 4BS6A 3OVZA 3NHEA 1PPDA 4FIPA 4I04A 3IEJA 3RVXA 2F1GA 8PCHA 1M6DA 1POPA 4RF1A 1MHWA 1MS6A 2YJ9A 5PADA 3H6SA 3KSEA 4N79A 3C9EA 1F29A 3O1GA 3PT2A 4Q8HA 3RVWA 1YALA 4PP1A 3LFYA 2DOSA 4IUMA 5F02A 3BY4A 4QH6A 5EF4A 3QSDA 3F5VA 1PPPA 2FT2A 2CB5A 1K3BB 3P5WA 1EWLA 4PADA 1MDWA 3V6EA 3ZNHA 2ATOA 1GCBA 3K8UA 3AI8A 3K9MA 2JQFR 4BSQA 1QXPA 2B1NA 1NB3A 1PBHA 2YJBA 2FTDA 1F2AA 1STFE 2FYEA 2GFOA 1AYWA 3PNRA 3S3RA 1GMYA 2HWKA 4KLBA 3N3KA 2IBIA 1GECE 5CVNB 1PVJA 2JTCA 3OQCA 4N8WA 1QDQA 4YVAA 4BS5A 3GCBA 2P0RA 4DMYA 1AIMA 1VJVA 4YYSA 7PCKA 3KKUA 3TNXA 2OZ2A 4BOQA 2FQ9A 3MTNA 2P86A 2XU4A 1Y08A 3PW3A 1BGOA 1FH0A 1IWDA 3E9SA 3OF8A 1CB5A 3QJ3A 5CVMA 3PBHA 1YT7A 1BP4A 1KHQA 2HHNA 3BCNA 3KW9A 2G7YA 3WXEA 4FJCA 2DCBA 3W30A 5K16A 4AXLA 1CS8A 1EWOA 4OELA 4FK5A 4QRXA 2NQIA 1SNKA 2VHSA 3WXGA 1ATKA 3O0UA 2Y5BA 3D6SA 2ACTA 1TU6A 5EZQA 1TL9A 4RF0A 4BOPA 3BWKA 3P5VA 2NQAA 2CIOA 3O65A 2R6NA 2HH5A 3MJ5A 5FPWA 1CPJA 4X6IA 4M0WA 3CBJA 1ME4A 3OVXA 2FRQA 4BQVA 1KXRA 1MEMA 4PI3A 2Z84A 2FE8A 2Y6EA 3ERVA 5EGWA 4XUIA 1CQDA 2P7UA 2AGAA 2DC6A 4YYUA 2HXZA 1ZIVA 2FUDA 2UZJA 4CDDB 2DC8A 1MEGA 3KWBX 3N4CA 4P6GA 3C0RA 1GLOA 2PNSA 4K7CA 1NPZA 4MZSA 1NLJA 4MI7A 1ITOA 4G54A 1YK7A 1UKFA 5CVOB 4MM3B 1SP4B 3H8CA 3PHXA 2VHFA 3IMAA 1F2CA 1PXVA 2O6XA 3M99A 3MP2A 4HWYA 2R9OA 1HUCB 2AS8A 1JQPA 1KFUL 3KX1A 2DJGB 2YJCA 2XU5A 4WURA 2AYOA 3TMPA 3P5UA 2BTWB 1AU2A 3N3GA 3MTVA 3I3TA 4D8EA 4QBBA 3ZUAA 1S4VA 2B1MA 1PE6A 2G8JA 4YV8A 3IOQA 1KHPA 1CVZA 1PADA 2FO5A 3BOWA 3P5XA 3PHWA 4MSXA 1BQIA 2R9NA 4ZUXU 4BPVA 1XKGA 2DC9A 3IHPA 3H7DA 1AU4A 4PT5A 1AU0A 2XU3A 2H7JA 3K24A 1TLOA 3F75A 4OW0A 2BDZA 4D8BA 1DEUA 2PBHA 3MHHA 2FRAA 5EZSA 4BOSA 2AUZA 1ICFA 2PREA 4YYRA 1U5IA 2GHUA 3HD3A 3HWNA 4HXDB 2AUXA 3BBAA 2AVWA 1U9WA 4BOZA 5JH3A 1Q6KA 4YYVA 5J94A 2DJFB 1KFXL 3KWZA 4PP2E 1QOLA 4R3DA 2NQGA 1CJLA 2YJ2A 3S3QA 3TRKA 5JZEA 2AIMA 3B21A 2BDLA 3V6CA 2JQGR 1YK8A 2DZZA 3PRMA 2ARYA 4YYWA 2E03A 2G6DA 1AECA 2AU1A 2G8EA 1U9XA 1YZBA 2XU1A 4CDFB 1DF0A 1PPOA 1AYVA 1X9YA 1NQCA 2BU3A 2BTWA 3MORA 4W5CA 4W5BA 4X6JA 3PDFA 3CH3X 2HD5A 1THEA 3CBKA 3OISA 2OP3A 3BPMA 4D8IA 3QT4A 4RNAA 4P6EA 1MIRA 3CH2X 2DZYA 4QRGA 4DMXA 2DCCA 4Q8GA 1EF7A 4N4ZA 4OVZA 1ME3A 1ZCMA 1AYUA 2JRIA 1F2BA 1DKIA 1PPNA 2J7QC 1NB5A 3PSEA 3I06A 2NQDB 5E6JA 2PADA 4W4UA 4MZOA 4WA6A 1PCIA 2R9MA 1CSBB 4P16A 3RNVA 4X6HA 2AYNA 4OEMA 4RKXA 1AU3A 4OVZB 1EWPA 3H8BA 3BPFA 2E01A 2DCAA 9PAPA 1Y4HA 6PADA 1O0EA 3OF9A 2YJ8A 5KO3A 5JA7A 3MHSA 2F7DA 1BY8A 3PRPA 2IPPB 5CHTA 4AXMA 1CTEA 1U9VA 3B79A 1CV8A
chains in the Genus database with same CATH topology
3RVVA 2E02A 3KFQA 2BSZA 3IUTA 3BC3A 3HHIA 1EWMA 2R9CA 4I05A 4XR7A 1PIPA 4CDEB 4I07A 3IV2A 2C0YA 2OULA 3U8EA 4QRVA 1U9QX 4YYQA 2E00A 3LXSA 3USVA 3WXFA 4CZWA 1NL6A 1A6RA 2DC7A 4CDCB 1VSNA 3H89A 1YVBA 3DF0A 2DCDA 3E1ZB 5CHVA 2R9FA 2WBFX 1QMYA 4RY2A 3HHAA 5A24A 4BS6A 3OVZA 3NHEA 1PPDA 4FIPA 4I04A 3IEJA 3RVXA 2F1GA 8PCHA 1M6DA 1POPA 1MHWA 1MS6A 2YJ9A 5PADA 3H6SA 3KSEA 4N79A 3C9EA 1F29A 3O1GA 4Q8HA 4NV7A 1YALA 4PP1A 3RVWA 3LFYA 5F02A 4QH6A 5EF4A 3QSDA 3F5VA 1PPPA 2FT2A 2CB5A 1K3BB 3P5WA 1EWLA 2VFBA 4PADA 1MDWA 3V6EA 2ATOA 1GCBA 3K8UA 3AI8A 3K9MA 2JQFR 4BSQA 1QXPA 2B1NA 1NB3A 1PBHA 2YJBA 2FTDA 1F2AA 1STFE 2FYEA 2GFOA 1W5RA 1AYWA 3PNRA 3S3RA 1GMYA 4KLBA 3N3KA 2IBIA 1GECE 4BGFA 5CVNB 1W6FA 4N8WA 1QDQA 4YVAA 4BS5A 3GCBA 2P0RA 4DMYA 1AIMA 1VJVA 4YYSA 7PCKA 3KKUA 3TNXA 2OZ2A 2FQ9A 3MTNA 2P86A 2XU4A 1Y08A 3PW3A 1BGOA 1FH0A 1IWDA 3OF8A 1CB5A 3QJ3A 5CVMA 3PBHA 1YT7A 1BP4A 1KHQA 2HHNA 3BCNA 3KW9A 2G7YA 3WXEA 2VFCA 4FJCA 2DCBA 5K16A 4AXLA 1CS8A 1EWOA 3D9WA 4FK5A 4OELA 4QRXA 2NQIA 1SNKA 2VHSA 3WXGA 1ATKA 3O0UA 2Y5BA 3D6SA 2ACTA 1TU6A 1TL9A 4C5PA 3BWKA 3P5VA 2NQAA 2CIOA 2R6NA 2HH5A 5FPWA 1CPJA 4X6IA 1W4TA 3CBJA 1ME4A 3OVXA 2FRQA 4BQVA 1KXRA 1MEMA 4PI3A 3LTWA 2Y6EA 3ERVA 5EGWA 4XUIA 1CQDA 2P7UA 2DC6A 4YYUA 2HXZA 1ZIVA 2FUDA 4CDDB 2DC8A 1MEGA 3KWBX 3N4CA 4P6GA 1GLOA 2PNSA 4K7CA 1NPZA 4MZSA 1NLJA 1ITOA 4G54A 1YK7A 5CVOB 1SP4B 3H8CA 2VHFA 3IMAA 1F2CA 1PXVA 2O6XA 3M99A 4HWYA 2R9OA 1HUCB 2AS8A 1JQPA 1KFUL 3KX1A 2DJGB 2YJCA 2XU5A 2AYOA 3P5UA 1AU2A 3N3GA 3I3TA 4QBBA 3ZUAA 1S4VA 2B1MA 1PE6A 2G8JA 4YV8A 3IOQA 4NV8A 1KHPA 1CVZA 1PADA 2FO5A 3BOWA 3P5XA 4MSXA 1BQIA 2R9NA 4ZUXU 4BPVA 1XKGA 2DC9A 3IHPA 3H7DA 1AU4A 1AU0A 2XU3A 1GX3A 2H7JA 3K24A 1TLOA 3F75A 2BDZA 1DEUA 2PBHA 3MHHA 2FRAA 2AUZA 1ICFA 2PREA 4YYRA 1U5IA 2GHUA 3HD3A 3HWNA 2AUXA 2AVWA 1U9WA 5JH3A 1Q6KA 4YYVA 5J94A 2DJFB 1KFXL 4B55A 3KWZA 4PP2E 1QOLA 2NQGA 1CJLA 2YJ2A 3S3QA 4GUZA 2AIMA 2BDLA 3V6CA 2JQGR 1YK8A 2DZZA 2ARYA 4YYWA 2E03A 2G6DA 1AECA 2AU1A 2G8EA 1U9XA 2XU1A 4CDFB 1DF0A 1PPOA 1AYVA 1X9YA 1NQCA 3MORA 4W5CA 4W5BA 4X6JA 3PDFA 3CH3X 2HD5A 1THEA 3CBKA 1E2TA 3OISA 2OP3A 3BPMA 3QT4A 4P6EA 1MIRA 3CH2X 2DZYA 4QRGA 4DMXA 2DCCA 4Q8GA 1EF7A 4N4ZA 1ME3A 1ZCMA 1AYUA 1F2BA 1PPNA 1NB5A 3I06A 2NQDB 2PADA 4W4UA 4MZOA 4WA6A 1PCIA 2R9MA 1CSBB 4X6HA 2AYNA 4OEMA 1AU3A 1EWPA 3H8BA 3BPFA 2E01A 2DCAA 9PAPA 1Y4HA 6PADA 1O0EA 3OF9A 2YJ8A 5JA7A 3MHSA 2F7DA 1BY8A 2IPPB 5CHTA 4AXMA 1CTEA 1U9VA 3B79A 1CV8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RVV A;  2E02 A;  3KFQ A;  3IUT A;  3BC3 A;  3HHI A;  1EWM A;  2R9C A;  4I05 A;  4XR7 A;  1PIP A;  4CDE B;  4I07 A;  3IV2 A;  2C0Y A;  2OUL A;  3U8E A;  4QRV A;  1U9Q X;  4YYQ A;  2E00 A;  3LXS A;  3USV A;  3WXF A;  4CZW A;  1NL6 A;  1A6R A;  2DC7 A;  4CDC B;  1VSN A;  3H89 A;  1YVB A;  3DF0 A;  2DCD A;  3E1Z B;  5CHV A;  2R9F A;  2WBF X;  1QMY A;  4RY2 A;  3HHA A;  5A24 A;  4BS6 A;  3OVZ A;  3NHE A;  1PPD A;  4FIP A;  4I04 A;  3IEJ A;  3RVX A;  2F1G A;  8PCH A;  1M6D A;  1POP A;  1MHW A;  1MS6 A;  2YJ9 A;  5PAD A;  3H6S A;  3KSE A;  4N79 A;  3C9E A;  1F29 A;  3O1G A;  4Q8H A;  3RVW A;  1YAL A;  4PP1 A;  3LFY A;  5F02 A;  4QH6 A;  5EF4 A;  3QSD A;  3F5V A;  1PPP A;  2FT2 A;  2CB5 A;  1K3B B;  3P5W A;  1EWL A;  4PAD A;  1MDW A;  3V6E A;  2ATO A;  1GCB A;  3K8U A;  3AI8 A;  3K9M A;  2JQF R;  4BSQ A;  1QXP A;  2B1N A;  1NB3 A;  1PBH A;  2YJB A;  2FTD A;  1F2A A;  1STF E;  2FYE A;  2GFO A;  1AYW A;  3PNR A;  3S3R A;  1GMY A;  4KLB A;  3N3K A;  2IBI A;  1GEC E;  5CVN B;  4N8W A;  1QDQ A;  4YVA A;  4BS5 A;  3GCB A;  2P0R A;  4DMY A;  1AIM A;  1VJV A;  4YYS A;  7PCK A;  3KKU A;  3TNX A;  2OZ2 A;  2FQ9 A;  3MTN A;  2P86 A;  2XU4 A;  1Y08 A;  3PW3 A;  1BGO A;  1FH0 A;  1IWD A;  3OF8 A;  1CB5 A;  3QJ3 A;  5CVM A;  3PBH A;  1YT7 A;  1BP4 A;  1KHQ A;  2HHN A;  3BCN A;  3KW9 A;  2G7Y A;  3WXE A;  4FJC A;  2DCB A;  5K16 A;  4AXL A;  1CS8 A;  1EWO A;  4OEL A;  4FK5 A;  4QRX A;  2NQI A;  1SNK A;  2VHS A;  3WXG A;  1ATK A;  3O0U A;  2Y5B A;  3D6S A;  2ACT A;  1TU6 A;  1TL9 A;  3BWK A;  3P5V A;  2NQA A;  2CIO A;  2R6N A;  2HH5 A;  5FPW A;  1CPJ A;  4X6I A;  3CBJ A;  1ME4 A;  3OVX A;  2FRQ A;  4BQV A;  1KXR A;  1MEM A;  4PI3 A;  2Y6E A;  3ERV A;  5EGW A;  4XUI A;  1CQD A;  2P7U A;  2DC6 A;  4YYU A;  2HXZ A;  1ZIV A;  2FUD A;  4CDD B;  2DC8 A;  1MEG A;  3KWB X;  3N4C A;  4P6G A;  1GLO A;  2PNS A;  4K7C A;  1NPZ A;  4MZS A;  1NLJ A;  1ITO A;  4G54 A;  1YK7 A;  5CVO B;  1SP4 B;  3H8C A;  2VHF A;  3IMA A;  1F2C A;  1PXV A;  2O6X A;  3M99 A;  4HWY A;  2R9O A;  1HUC B;  2AS8 A;  1JQP A;  1KFU L;  3KX1 A;  2DJG B;  2YJC A;  2XU5 A;  2AYO A;  3P5U A;  1AU2 A;  3N3G A;  3I3T A;  4QBB A;  3ZUA A;  1S4V A;  2B1M A;  1PE6 A;  2G8J A;  4YV8 A;  3IOQ A;  1KHP A;  1CVZ A;  1PAD A;  2FO5 A;  3BOW A;  3P5X A;  4MSX A;  1BQI A;  2R9N A;  4ZUX U;  4BPV A;  1XKG A;  2DC9 A;  3IHP A;  3H7D A;  1AU4 A;  1AU0 A;  2XU3 A;  2H7J A;  3K24 A;  1TLO A;  3F75 A;  2BDZ A;  1DEU A;  2PBH A;  3MHH A;  2FRA A;  2AUZ A;  1ICF A;  2PRE A;  4YYR A;  1U5I A;  2GHU A;  3HD3 A;  3HWN A;  2AUX A;  2AVW A;  1U9W A;  5JH3 A;  1Q6K A;  4YYV A;  5J94 A;  2DJF B;  1KFX L;  3KWZ A;  4PP2 E;  1QOL A;  2NQG A;  1CJL A;  2YJ2 A;  3S3Q A;  2AIM A;  2BDL A;  3V6C A;  2JQG R;  1YK8 A;  2DZZ A;  2ARY A;  4YYW A;  2E03 A;  2G6D A;  1AEC A;  2AU1 A;  2G8E A;  1U9X A;  2XU1 A;  4CDF B;  1DF0 A;  1PPO A;  1AYV A;  1X9Y A;  1NQC A;  3MOR A;  4W5C A;  4W5B A;  4X6J A;  3PDF A;  3CH3 X;  2HD5 A;  1THE A;  3CBK A;  3OIS A;  2OP3 A;  3BPM A;  3QT4 A;  4P6E A;  1MIR A;  3CH2 X;  2DZY A;  4QRG A;  4DMX A;  2DCC A;  4Q8G A;  1EF7 A;  4N4Z A;  1ME3 A;  1ZCM A;  1AYU A;  1F2B A;  1PPN A;  1NB5 A;  3I06 A;  2NQD B;  2PAD A;  4W4U A;  4MZO A;  4WA6 A;  1PCI A;  2R9M A;  1CSB B;  4X6H A;  2AYN A;  4OEM A;  1AU3 A;  1EWP A;  3H8B A;  3BPF A;  2E01 A;  2DCA A;  9PAP A;  1Y4H A;  6PAD A;  1O0E A;  3OF9 A;  2YJ8 A;  5JA7 A;  3MHS A;  2F7D A;  1BY8 A;  2IPP B;  5CHT A;  4AXM A;  1CTE A;  1U9V A;  3B79 A;  1CV8 A; 
#chains in the Genus database with same CATH topology
 4XZX A;  3RVV A;  2E02 A;  3BB7 A;  3KFQ A;  4ZTB A;  3IUT A;  4BOU A;  3BC3 A;  4IP3 A;  3HHI A;  4A5U A;  1EWM A;  2R9C A;  3PHU A;  4I05 A;  4XR7 A;  1PIP A;  4CDE B;  3IFU A;  4I07 A;  2J7Q A;  3IV2 A;  2C0Y A;  2OUL A;  3U8E A;  4QRV A;  1U9Q X;  4YYQ A;  2E00 A;  3LXS A;  3USV A;  3WXF A;  4CZW A;  1NL6 A;  1A6R A;  2DC7 A;  4CDC B;  1VSN A;  3H89 A;  1YVB A;  3DF0 A;  2DCD A;  3E1Z B;  5CHV A;  3W31 A;  2R9F A;  2WBF X;  1QMY A;  4GUA A;  4RY2 A;  3HHA A;  4REZ A;  5A24 A;  4BS6 A;  3OVZ A;  3NHE A;  1PPD A;  4FIP A;  4I04 A;  3IEJ A;  3RVX A;  2F1G A;  8PCH A;  1M6D A;  1POP A;  4RF1 A;  1MHW A;  1MS6 A;  2YJ9 A;  5PAD A;  3H6S A;  3KSE A;  4N79 A;  3C9E A;  1F29 A;  3O1G A;  3PT2 A;  4Q8H A;  3RVW A;  1YAL A;  4PP1 A;  3LFY A;  2DOS A;  4IUM A;  5F02 A;  3BY4 A;  4QH6 A;  5EF4 A;  3QSD A;  3F5V A;  1PPP A;  2FT2 A;  2CB5 A;  1K3B B;  3P5W A;  1EWL A;  4PAD A;  1MDW A;  3V6E A;  3ZNH A;  2ATO A;  1GCB A;  3K8U A;  3AI8 A;  3K9M A;  2JQF R;  4BSQ A;  1QXP A;  2B1N A;  1NB3 A;  1PBH A;  2YJB A;  2FTD A;  1F2A A;  1STF E;  2FYE A;  2GFO A;  1AYW A;  3PNR A;  3S3R A;  1GMY A;  2HWK A;  4KLB A;  3N3K A;  2IBI A;  1GEC E;  5CVN B;  1PVJ A;  2JTC A;  3OQC A;  4N8W A;  1QDQ A;  4YVA A;  4BS5 A;  3GCB A;  2P0R A;  4DMY A;  1AIM A;  1VJV A;  4YYS A;  7PCK A;  3KKU A;  3TNX A;  2OZ2 A;  4BOQ A;  2FQ9 A;  3MTN A;  2P86 A;  2XU4 A;  1Y08 A;  3PW3 A;  1BGO A;  1FH0 A;  1IWD A;  3E9S A;  3OF8 A;  1CB5 A;  3QJ3 A;  5CVM A;  3PBH A;  1YT7 A;  1BP4 A;  1KHQ A;  2HHN A;  3BCN A;  3KW9 A;  2G7Y A;  3WXE A;  4FJC A;  2DCB A;  3W30 A;  5K16 A;  4AXL A;  1CS8 A;  1EWO A;  4OEL A;  4FK5 A;  4QRX A;  2NQI A;  1SNK A;  2VHS A;  3WXG A;  1ATK A;  3O0U A;  2Y5B A;  3D6S A;  2ACT A;  1TU6 A;  5EZQ A;  1TL9 A;  4RF0 A;  4BOP A;  3BWK A;  3P5V A;  2NQA A;  2CIO A;  3O65 A;  2R6N A;  2HH5 A;  3MJ5 A;  5FPW A;  1CPJ A;  4X6I A;  4M0W A;  3CBJ A;  1ME4 A;  3OVX A;  2FRQ A;  4BQV A;  1KXR A;  1MEM A;  4PI3 A;  2Z84 A;  2FE8 A;  2Y6E A;  3ERV A;  5EGW A;  4XUI A;  1CQD A;  2P7U A;  2AGA A;  2DC6 A;  4YYU A;  2HXZ A;  1ZIV A;  2FUD A;  2UZJ A;  4CDD B;  2DC8 A;  1MEG A;  3KWB X;  3N4C A;  4P6G A;  3C0R A;  1GLO A;  2PNS A;  4K7C A;  1NPZ A;  4MZS A;  1NLJ A;  4MI7 A;  1ITO A;  4G54 A;  1YK7 A;  1UKF A;  5CVO B;  4MM3 B;  1SP4 B;  3H8C A;  3PHX A;  2VHF A;  3IMA A;  1F2C A;  1PXV A;  2O6X A;  3M99 A;  3MP2 A;  4HWY A;  2R9O A;  1HUC B;  2AS8 A;  1JQP A;  1KFU L;  3KX1 A;  2DJG B;  2YJC A;  2XU5 A;  4WUR A;  2AYO A;  3TMP A;  3P5U A;  2BTW B;  1AU2 A;  3N3G A;  3MTV A;  3I3T A;  4D8E A;  4QBB A;  3ZUA A;  1S4V A;  2B1M A;  1PE6 A;  2G8J A;  4YV8 A;  3IOQ A;  1KHP A;  1CVZ A;  1PAD A;  2FO5 A;  3BOW A;  3P5X A;  3PHW A;  4MSX A;  1BQI A;  2R9N A;  4ZUX U;  4BPV A;  1XKG A;  2DC9 A;  3IHP A;  3H7D A;  1AU4 A;  4PT5 A;  1AU0 A;  2XU3 A;  2H7J A;  3K24 A;  1TLO A;  3F75 A;  4OW0 A;  2BDZ A;  4D8B A;  1DEU A;  2PBH A;  3MHH A;  2FRA A;  5EZS A;  4BOS A;  2AUZ A;  1ICF A;  2PRE A;  4YYR A;  1U5I A;  2GHU A;  3HD3 A;  3HWN A;  4HXD B;  2AUX A;  3BBA A;  2AVW A;  1U9W A;  4BOZ A;  5JH3 A;  1Q6K A;  4YYV A;  5J94 A;  2DJF B;  1KFX L;  3KWZ A;  4PP2 E;  1QOL A;  4R3D A;  2NQG A;  1CJL A;  2YJ2 A;  3S3Q A;  3TRK A;  5JZE A;  2AIM A;  3B21 A;  2BDL A;  3V6C A;  2JQG R;  1YK8 A;  2DZZ A;  3PRM A;  2ARY A;  4YYW A;  2E03 A;  2G6D A;  1AEC A;  2AU1 A;  2G8E A;  1U9X A;  1YZB A;  2XU1 A;  4CDF B;  1DF0 A;  1PPO A;  1AYV A;  1X9Y A;  1NQC A;  2BU3 A;  2BTW A;  3MOR A;  4W5C A;  4W5B A;  4X6J A;  3PDF A;  3CH3 X;  2HD5 A;  1THE A;  3CBK A;  3OIS A;  2OP3 A;  3BPM A;  4D8I A;  3QT4 A;  4RNA A;  4P6E A;  1MIR A;  3CH2 X;  2DZY A;  4QRG A;  4DMX A;  2DCC A;  4Q8G A;  1EF7 A;  4N4Z A;  4OVZ A;  1ME3 A;  1ZCM A;  1AYU A;  2JRI A;  1F2B A;  1DKI A;  1PPN A;  2J7Q C;  1NB5 A;  3PSE A;  3I06 A;  2NQD B;  5E6J A;  2PAD A;  4W4U A;  4MZO A;  4WA6 A;  1PCI A;  2R9M A;  1CSB B;  4P16 A;  3RNV A;  4X6H A;  2AYN A;  4OEM A;  4RKX A;  1AU3 A;  4OVZ B;  1EWP A;  3H8B A;  3BPF A;  2E01 A;  2DCA A;  9PAP A;  1Y4H A;  6PAD A;  1O0E A;  3OF9 A;  2YJ8 A;  5KO3 A;  5JA7 A;  3MHS A;  2F7D A;  1BY8 A;  3PRP A;  2IPP B;  5CHT A;  4AXM A;  1CTE A;  1U9V A;  3B79 A;  1CV8 A; 
#chains in the Genus database with same CATH homology
 3RVV A;  2E02 A;  3KFQ A;  2BSZ A;  3IUT A;  3BC3 A;  3HHI A;  1EWM A;  2R9C A;  4I05 A;  4XR7 A;  1PIP A;  4CDE B;  4I07 A;  3IV2 A;  2C0Y A;  2OUL A;  3U8E A;  4QRV A;  1U9Q X;  4YYQ A;  2E00 A;  3LXS A;  3USV A;  3WXF A;  4CZW A;  1NL6 A;  1A6R A;  2DC7 A;  4CDC B;  1VSN A;  3H89 A;  1YVB A;  3DF0 A;  2DCD A;  3E1Z B;  5CHV A;  2R9F A;  2WBF X;  1QMY A;  4RY2 A;  3HHA A;  5A24 A;  4BS6 A;  3OVZ A;  3NHE A;  1PPD A;  4FIP A;  4I04 A;  3IEJ A;  3RVX A;  2F1G A;  8PCH A;  1M6D A;  1POP A;  1MHW A;  1MS6 A;  2YJ9 A;  5PAD A;  3H6S A;  3KSE A;  4N79 A;  3C9E A;  1F29 A;  3O1G A;  4Q8H A;  4NV7 A;  1YAL A;  4PP1 A;  3RVW A;  3LFY A;  5F02 A;  4QH6 A;  5EF4 A;  3QSD A;  3F5V A;  1PPP A;  2FT2 A;  2CB5 A;  1K3B B;  3P5W A;  1EWL A;  2VFB A;  4PAD A;  1MDW A;  3V6E A;  2ATO A;  1GCB A;  3K8U A;  3AI8 A;  3K9M A;  2JQF R;  4BSQ A;  1QXP A;  2B1N A;  1NB3 A;  1PBH A;  2YJB A;  2FTD A;  1F2A A;  1STF E;  2FYE A;  2GFO A;  1W5R A;  1AYW A;  3PNR A;  3S3R A;  1GMY A;  4KLB A;  3N3K A;  2IBI A;  1GEC E;  4BGF A;  5CVN B;  1W6F A;  4N8W A;  1QDQ A;  4YVA A;  4BS5 A;  3GCB A;  2P0R A;  4DMY A;  1AIM A;  1VJV A;  4YYS A;  7PCK A;  3KKU A;  3TNX A;  2OZ2 A;  2FQ9 A;  3MTN A;  2P86 A;  2XU4 A;  1Y08 A;  3PW3 A;  1BGO A;  1FH0 A;  1IWD A;  3OF8 A;  1CB5 A;  3QJ3 A;  5CVM A;  3PBH A;  1YT7 A;  1BP4 A;  1KHQ A;  2HHN A;  3BCN A;  3KW9 A;  2G7Y A;  3WXE A;  2VFC A;  4FJC A;  2DCB A;  5K16 A;  4AXL A;  1CS8 A;  1EWO A;  3D9W A;  4FK5 A;  4OEL A;  4QRX A;  2NQI A;  1SNK A;  2VHS A;  3WXG A;  1ATK A;  3O0U A;  2Y5B A;  3D6S A;  2ACT A;  1TU6 A;  1TL9 A;  4C5P A;  3BWK A;  3P5V A;  2NQA A;  2CIO A;  2R6N A;  2HH5 A;  5FPW A;  1CPJ A;  4X6I A;  1W4T A;  3CBJ A;  1ME4 A;  3OVX A;  2FRQ A;  4BQV A;  1KXR A;  1MEM A;  4PI3 A;  3LTW A;  2Y6E A;  3ERV A;  5EGW A;  4XUI A;  1CQD A;  2P7U A;  2DC6 A;  4YYU A;  2HXZ A;  1ZIV A;  2FUD A;  4CDD B;  2DC8 A;  1MEG A;  3KWB X;  3N4C A;  4P6G A;  1GLO A;  2PNS A;  4K7C A;  1NPZ A;  4MZS A;  1NLJ A;  1ITO A;  4G54 A;  1YK7 A;  5CVO B;  1SP4 B;  3H8C A;  2VHF A;  3IMA A;  1F2C A;  1PXV A;  2O6X A;  3M99 A;  4HWY A;  2R9O A;  1HUC B;  2AS8 A;  1JQP A;  1KFU L;  3KX1 A;  2DJG B;  2YJC A;  2XU5 A;  2AYO A;  3P5U A;  1AU2 A;  3N3G A;  3I3T A;  4QBB A;  3ZUA A;  1S4V A;  2B1M A;  1PE6 A;  2G8J A;  4YV8 A;  3IOQ A;  4NV8 A;  1KHP A;  1CVZ A;  1PAD A;  2FO5 A;  3BOW A;  3P5X A;  4MSX A;  1BQI A;  2R9N A;  4ZUX U;  4BPV A;  1XKG A;  2DC9 A;  3IHP A;  3H7D A;  1AU4 A;  1AU0 A;  2XU3 A;  1GX3 A;  2H7J A;  3K24 A;  1TLO A;  3F75 A;  2BDZ A;  1DEU A;  2PBH A;  3MHH A;  2FRA A;  2AUZ A;  1ICF A;  2PRE A;  4YYR A;  1U5I A;  2GHU A;  3HD3 A;  3HWN A;  2AUX A;  2AVW A;  1U9W A;  5JH3 A;  1Q6K A;  4YYV A;  5J94 A;  2DJF B;  1KFX L;  4B55 A;  3KWZ A;  4PP2 E;  1QOL A;  2NQG A;  1CJL A;  2YJ2 A;  3S3Q A;  4GUZ A;  2AIM A;  2BDL A;  3V6C A;  2JQG R;  1YK8 A;  2DZZ A;  2ARY A;  4YYW A;  2E03 A;  2G6D A;  1AEC A;  2AU1 A;  2G8E A;  1U9X A;  2XU1 A;  4CDF B;  1DF0 A;  1PPO A;  1AYV A;  1X9Y A;  1NQC A;  3MOR A;  4W5C A;  4W5B A;  4X6J A;  3PDF A;  3CH3 X;  2HD5 A;  1THE A;  3CBK A;  1E2T A;  3OIS A;  2OP3 A;  3BPM A;  3QT4 A;  4P6E A;  1MIR A;  3CH2 X;  2DZY A;  4QRG A;  4DMX A;  2DCC A;  4Q8G A;  1EF7 A;  4N4Z A;  1ME3 A;  1ZCM A;  1AYU A;  1F2B A;  1PPN A;  1NB5 A;  3I06 A;  2NQD B;  2PAD A;  4W4U A;  4MZO A;  4WA6 A;  1PCI A;  2R9M A;  1CSB B;  4X6H A;  2AYN A;  4OEM A;  1AU3 A;  1EWP A;  3H8B A;  3BPF A;  2E01 A;  2DCA A;  9PAP A;  1Y4H A;  6PAD A;  1O0E A;  3OF9 A;  2YJ8 A;  5JA7 A;  3MHS A;  2F7D A;  1BY8 A;  2IPP B;  5CHT A;  4AXM A;  1CTE A;  1U9V A;  3B79 A;  1CV8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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