2XU1A

Cathepsin l with a nitrile inhibitor
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
220
structure length
215
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFENNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CATHEPSIN L1
total genus 70
structure length 215
sequence length 220
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2010-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2xu1A00
5CVMA 2BDLA 1PPPA 3AI8A 4P6EA 1AU3A 3BCNA 2JQGR 3MHHA 3P5WA 2OP3A 4W4UA 2B1MA 4YYUA 4XUIA 3TNXA 4YYVA 3N3KA 3DF0A 3ZUAA 2PREA 1ME3A 1STFE 5EF4A 1AIMA 3H8BA 4YYSA 3IMAA 3GCBA 3P5UA 3K9MA 3KSEA 3MHSA 1NB5A 1MHWA 3PBHA 1DEUA 2CIOA 1PPOA 1PPDA 2E02A 4YYRA 4X6IA 2NQDB 2E00A 4KLBA 3U8EA 4MZOA 2R9NA 1F2CA 1YK7A 2P0RA 1PPNA 2F1GA 2AVWA 2AU1A 3KW9A 1QOLA 1QMYA 1YT7A 2HD5A 2F7DA 1TU6A 1KHPA 1KFXL 2G8JA 4FJCA 1GMYA 1U9XA 3RVVA 1Y4HA 4AXMA 2R6NA 4CDEB 4CDCB 2R9FA 4BS5A 3PNRA 4WA6A 3F75A 4XR7A 3I06A 3H89A 3QSDA 1AYWA 1CVZA 1JQPA 2DC9A 1ZCMA 2FT2A 2Y5BA 2DCBA 1MIRA 3WXEA 2FRAA 2YJBA 3O0UA 2AYOA 1FH0A 1NLJA 2XU3A 4CZWA 1Y08A 2PNSA 4I04A 3E1ZB 4BSQA 1AYUA 3OVZA 2XU5A 4HWYA 7PCKA 3LFYA 1YVBA 2PBHA 3KWZA 5CVOB 4MZSA 3I3TA 4PADA 2DCAA 5J94A 2NQAA 1U9QX 3ERVA 2FYEA 1AYVA 5PADA 1PIPA 3V6CA 4BQVA 4I07A 3BC3A 3O1GA 4N79A 1M6DA 2IPPB 2B1NA 4G54A 3BOWA 4AXLA 1NB3A 3NHEA 3BPMA 3IV2A 4OELA 1VJVA 1QDQA 1SNKA 1AU4A 1EWPA 3HHIA 4PI3A 1MEMA 1SP4B 1PXVA 1THEA 3KWBX 2ACTA 1Q6KA 1NL6A 1AU0A 1F2BA 4YV8A 4MSXA 2P7UA 1EWMA 4X6HA 1EF7A 2Y6EA 2FTDA 4QRVA 2FRQA 3WXFA 2P86A 4BPVA 4Q8HA 1YALA 3OF8A 2XU1A 3KFQA 3BWKA 1ICFA 2WBFX 2R9MA 3KX1A 1CS8A 2GHUA 2DCCA 2HHNA 5CHVA 3CBKA 2XU4A 2VHSA 1DF0A 1MDWA 4QH6A 1CV8A 1GLOA 4PP1A 1PBHA 4CDFB 1U9WA 3D6SA 1BP4A 1KFUL 9PAPA 1EWLA 4I05A 1F2AA 5CHTA 1K3BB 1KXRA 2YJ8A 2AUXA 1ZIVA 1TL9A 3IHPA 1AU2A 8PCHA 2DZZA 2G7YA 1X9YA 4FK5A 2C0YA 3KKUA 3WXGA 1XKGA 2DJGB 2FUDA 2AIMA 1BQIA 2ARYA 2YJCA 5K16A 4P6GA 2R9OA 2DZYA 2BDZA 2FQ9A 3CH2X 2AUZA 3QT4A 1GECE 5CVNB 4BS6A 3HHAA 3IOQA 4FIPA 1IWDA 1POPA 3K8UA 4ZUXU 4W5BA 3F5VA 2DCDA 2HH5A 2E01A 2PADA 3OVXA 2DC6A 4N8WA 4RY2A 1PCIA 2HXZA 2OULA 2O6XA 1BGOA 4DMXA 1U9VA 1TLOA 1PE6A 4PP2E 4CDDB 3P5XA 3OF9A 3RVXA 2IBIA 5F02A 1ITOA 3V6EA 3K24A 1AECA 1CB5A 3PW3A 4X6JA 3USVA 2GFOA 1MS6A 1VSNA 3BPFA 3OISA 3H6SA 3H7DA 5EGWA 1HUCB 1F29A 2NQGA 1CSBB 2YJ9A 4DMYA 2R9CA 3C9EA 3HD3A 6PADA 4K7CA 1KHQA 3RVWA 2H7JA 1YK8A 3MORA 1MEGA 1ME4A 4N4ZA 2DC8A 3S3QA 1CJLA 4QBBA 1CTEA 5JH3A 2YJ2A 3LXSA 3PDFA 1NPZA 3CH3X 1CPJA 2VHFA 2OZ2A 1BY8A 4QRGA 3M99A 1A6RA 2FO5A 3IUTA 3B79A 1ATKA 2DJFB 4OEMA 1S4VA 4W5CA 5FPWA 3HWNA 1GCBA 2AYNA 4Q8GA 1QXPA 3MTNA 4YYWA 2CB5A 3H8CA 3CBJA 3IEJA 3N3GA 3S3RA 5A24A 1O0EA 2DC7A 1U5IA 2AS8A 2G8EA 3P5VA 2NQIA 1CQDA 1NQCA 4QRXA 4YYQA 3QJ3A 1PADA 1EWOA 3N4CA 4YVAA 2ATOA 2G6DA 2JQFR 5JA7A 2E03A
chains in the Genus database with same CATH superfamily
3OQCA 4D8BA 5CVMA 2BDLA 1PPPA 3AI8A 4P6EA 1AU3A 3BCNA 2JQGR 3MHHA 3P5WA 2OP3A 4W4UA 2B1MA 4YYUA 4IP3A 4XUIA 2DOSA 3ZNHA 4BOZA 3TNXA 4YYVA 3N3KA 3DF0A 3E9SA 3ZUAA 2PREA 1ME3A 1STFE 4REZA 5EF4A 1AIMA 1YZBA 3H8BA 4YYSA 3IMAA 3GCBA 3P5UA 3K9MA 3KSEA 3MHSA 1NB5A 3PHUA 1MHWA 3PBHA 1DEUA 3IFUA 2CIOA 1PPOA 4ZTBA 1PPDA 2E02A 4YYRA 4X6IA 2NQDB 2E00A 4BOUA 4KLBA 3U8EA 4MZOA 2R9NA 1F2CA 1YK7A 2P0RA 1PPNA 2F1GA 2AVWA 2AU1A 3KW9A 1QOLA 1QMYA 3TMPA 1YT7A 4BOQA 2HD5A 2F7DA 1TU6A 1KHPA 1KFXL 2G8JA 4WURA 4FJCA 2HWKA 1GMYA 4IUMA 1U9XA 3RVVA 1Y4HA 2BTWA 4AXMA 2R6NA 4CDEB 4CDCB 2R9FA 4BS5A 3PNRA 4WA6A 3F75A 4XR7A 1PVJA 3I06A 2AGAA 3H89A 3QSDA 1AYWA 1CVZA 1JQPA 2DC9A 1ZCMA 2FT2A 2Y5BA 2DCBA 3PSEA 4PT5A 1MIRA 3WXEA 2FRAA 2YJBA 3O0UA 1UKFA 2AYOA 1FH0A 1NLJA 2XU3A 4CZWA 1Y08A 2PNSA 4I04A 3E1ZB 4BSQA 4R3DA 1AYUA 3OVZA 4RF1A 2XU5A 4HWYA 7PCKA 3LFYA 3O65A 1YVBA 2PBHA 3KWZA 5CVOB 4MZSA 3I3TA 4PADA 2DCAA 4OVZB 5J94A 3C0RA 2NQAA 1U9QX 5EZQA 3W31A 3ERVA 2FYEA 1AYVA 5PADA 1PIPA 3V6CA 4BQVA 4I07A 3BC3A 3O1GA 4N79A 1M6DA 2IPPB 2B1NA 4G54A 3BOWA 4AXLA 1NB3A 3NHEA 3BPMA 3IV2A 4OELA 2FE8A 1VJVA 1QDQA 1SNKA 1AU4A 1EWPA 3HHIA 4PI3A 1MEMA 1SP4B 1PXVA 1THEA 3MTVA 2BU3A 4M0WA 3KWBX 2ACTA 1Q6KA 1NL6A 1AU0A 1F2BA 4YV8A 4MSXA 2P7UA 3PRMA 5E6JA 1EWMA 4X6HA 1EF7A 2Y6EA 2FTDA 4QRVA 2Z84A 2FRQA 4D8EA 2J7QC 3WXFA 2P86A 4BPVA 4Q8HA 1YALA 3OF8A 2BTWB 2XU1A 3MJ5A 3KFQA 3BBAA 3BWKA 4XZXA 1ICFA 2WBFX 3RNVA 2R9MA 3KX1A 1CS8A 2GHUA 2DCCA 3B21A 2HHNA 5CHVA 3CBKA 2XU4A 2VHSA 1DF0A 1MDWA 4QH6A 1CV8A 1GLOA 4PP1A 3BB7A 1PBHA 4CDFB 1U9WA 3D6SA 1BP4A 1KFUL 4HXDB 9PAPA 1EWLA 4I05A 1F2AA 4RF0A 5CHTA 1K3BB 1KXRA 2YJ8A 4P16A 2AUXA 1ZIVA 1TL9A 3IHPA 1AU2A 8PCHA 2DZZA 2G7YA 1X9YA 4GUAA 4FK5A 2C0YA 3KKUA 3WXGA 1XKGA 2DJGB 2FUDA 2AIMA 1BQIA 2ARYA 2YJCA 4MM3B 5K16A 4P6GA 2R9OA 2DZYA 2BDZA 2FQ9A 3CH2X 4MI7A 2AUZA 3QT4A 1GECE 5CVNB 4BS6A 3HHAA 3IOQA 4FIPA 1IWDA 3K8UA 1POPA 4ZUXU 4W5BA 3F5VA 2DCDA 2HH5A 2E01A 2PADA 3OVXA 2DC6A 4N8WA 4RY2A 4OW0A 1PCIA 2HXZA 2OULA 2O6XA 3TRKA 1BGOA 4DMXA 1U9VA 1TLOA 2UZJA 1PE6A 4PP2E 1DKIA 4CDDB 4D8IA 3P5XA 3OF9A 4OVZA 3RVXA 2IBIA 5F02A 1ITOA 3V6EA 3K24A 1AECA 1CB5A 3PW3A 4X6JA 3USVA 2GFOA 1MS6A 1VSNA 3BPFA 2JRIA 3OISA 3H6SA 3H7DA 5EGWA 1HUCB 1F29A 2NQGA 1CSBB 2YJ9A 4DMYA 3MP2A 2R9CA 3C9EA 3PT2A 3HD3A 6PADA 5EZSA 4K7CA 1KHQA 3RVWA 4RKXA 3PRPA 2H7JA 1YK8A 3MORA 1MEGA 1ME4A 4N4ZA 2DC8A 3S3QA 1CJLA 4QBBA 1CTEA 5JH3A 2YJ2A 3LXSA 3PDFA 1NPZA 3CH3X 1CPJA 2VHFA 2OZ2A 1BY8A 3PHWA 5KO3A 4QRGA 4BOSA 3M99A 1A6RA 2FO5A 3IUTA 3B79A 4A5UA 1ATKA 5JZEA 2DJFB 4OEMA 1S4VA 4W5CA 5FPWA 4BOPA 3HWNA 1GCBA 2AYNA 4Q8GA 1QXPA 3MTNA 4YYWA 2CB5A 3H8CA 3CBJA 3IEJA 3N3GA 3W30A 3S3RA 5A24A 1O0EA 2DC7A 1U5IA 3BY4A 2AS8A 2G8EA 3P5VA 2NQIA 1CQDA 1NQCA 4QRXA 2J7QA 3PHXA 4YYQA 3QJ3A 2JTCA 1PADA 1EWOA 3N4CA 4RNAA 4YVAA 2ATOA 2G6DA 2JQFR 5JA7A 2E03A
chains in the Genus database with same CATH topology
5CVMA 2BDLA 1PPPA 3AI8A 4P6EA 1AU3A 3BCNA 2JQGR 3MHHA 3P5WA 2OP3A 4W4UA 2B1MA 4YYUA 4XUIA 3TNXA 4YYVA 3N3KA 3DF0A 3ZUAA 2PREA 1ME3A 1STFE 5EF4A 1AIMA 3H8BA 4YYSA 3IMAA 3GCBA 1W6FA 3P5UA 3K9MA 3KSEA 3MHSA 1NB5A 1MHWA 3PBHA 1DEUA 2CIOA 1PPOA 1PPDA 2E02A 4YYRA 4X6IA 2NQDB 2E00A 4KLBA 3U8EA 4MZOA 2R9NA 1F2CA 1YK7A 2P0RA 1PPNA 2F1GA 2AVWA 2AU1A 3KW9A 1QOLA 1QMYA 1YT7A 2HD5A 2F7DA 1TU6A 1KHPA 1KFXL 2G8JA 4FJCA 1GMYA 1U9XA 3RVVA 1Y4HA 4AXMA 2R6NA 4CDEB 4CDCB 2R9FA 4BS5A 3PNRA 4WA6A 3F75A 4XR7A 3I06A 3H89A 3QSDA 1AYWA 1CVZA 1JQPA 2DC9A 1ZCMA 2FT2A 2Y5BA 2DCBA 1MIRA 3WXEA 2FRAA 2YJBA 3O0UA 4NV8A 2AYOA 1FH0A 1NLJA 2XU3A 4CZWA 1Y08A 2PNSA 4I04A 3E1ZB 4BSQA 1AYUA 3OVZA 2XU5A 4HWYA 7PCKA 3LFYA 1YVBA 2PBHA 3KWZA 5CVOB 4MZSA 3I3TA 4PADA 2DCAA 5J94A 2NQAA 1U9QX 3ERVA 2FYEA 1AYVA 5PADA 1PIPA 3V6CA 4BQVA 4I07A 3BC3A 3O1GA 4N79A 1M6DA 2IPPB 2B1NA 4G54A 3BOWA 4AXLA 1NB3A 3NHEA 3BPMA 3IV2A 4OELA 1VJVA 1QDQA 1SNKA 1AU4A 1EWPA 3HHIA 4PI3A 1MEMA 1SP4B 1PXVA 1THEA 3KWBX 2ACTA 1Q6KA 1NL6A 3LTWA 1AU0A 1F2BA 4YV8A 4MSXA 2P7UA 1EWMA 4X6HA 1EF7A 2Y6EA 2FTDA 4QRVA 2FRQA 3WXFA 2P86A 4BPVA 4Q8HA 1YALA 3OF8A 2XU1A 3KFQA 3BWKA 1ICFA 2WBFX 2R9MA 3KX1A 1CS8A 2GHUA 2DCCA 2HHNA 5CHVA 3CBKA 2XU4A 2BSZA 2VHSA 1DF0A 1MDWA 4QH6A 1CV8A 1GLOA 4PP1A 1PBHA 4CDFB 1U9WA 3D6SA 1BP4A 1KFUL 9PAPA 1EWLA 4I05A 1F2AA 5CHTA 4GUZA 1K3BB 1KXRA 2YJ8A 2AUXA 1ZIVA 1TL9A 3IHPA 1AU2A 8PCHA 2DZZA 2G7YA 1X9YA 4FK5A 2C0YA 3KKUA 3WXGA 1XKGA 2DJGB 2FUDA 2VFBA 2AIMA 1BQIA 2ARYA 2YJCA 5K16A 4P6GA 2R9OA 2DZYA 2BDZA 2FQ9A 3CH2X 2AUZA 3QT4A 1GECE 5CVNB 4BS6A 3HHAA 3IOQA 4FIPA 1IWDA 3K8UA 1POPA 4ZUXU 4W5BA 3F5VA 2DCDA 2HH5A 2E01A 2PADA 3OVXA 2DC6A 4N8WA 4RY2A 1PCIA 2HXZA 2OULA 2O6XA 1BGOA 4DMXA 1U9VA 1TLOA 1PE6A 4PP2E 4CDDB 3P5XA 3OF9A 3RVXA 2IBIA 5F02A 1ITOA 3V6EA 1GX3A 3K24A 1AECA 1CB5A 3PW3A 4X6JA 3USVA 2GFOA 1MS6A 1VSNA 3BPFA 3OISA 3H6SA 3H7DA 5EGWA 4B55A 1HUCB 1F29A 2NQGA 1CSBB 2YJ9A 4DMYA 1W5RA 2R9CA 3C9EA 3HD3A 6PADA 4K7CA 1KHQA 3RVWA 2H7JA 1YK8A 3MORA 1MEGA 1ME4A 4N4ZA 2DC8A 3S3QA 1CJLA 4QBBA 1CTEA 5JH3A 2YJ2A 3LXSA 3PDFA 1NPZA 3CH3X 1CPJA 2VHFA 2OZ2A 1BY8A 4QRGA 3M99A 1A6RA 2FO5A 3IUTA 3B79A 1ATKA 2DJFB 1E2TA 4OEMA 1S4VA 3D9WA 4BGFA 4W5CA 5FPWA 3HWNA 1GCBA 2VFCA 1W4TA 2AYNA 4Q8GA 1QXPA 3MTNA 4YYWA 2CB5A 3H8CA 3CBJA 4C5PA 3IEJA 3N3GA 3S3RA 5A24A 1O0EA 2DC7A 1U5IA 2AS8A 2G8EA 3P5VA 2NQIA 1CQDA 1NQCA 4QRXA 4YYQA 3QJ3A 1PADA 4NV7A 1EWOA 3N4CA 4YVAA 2ATOA 2G6DA 2JQFR 5JA7A 2E03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CVM A;  2BDL A;  1PPP A;  3AI8 A;  4P6E A;  1AU3 A;  3BCN A;  2JQG R;  3MHH A;  3P5W A;  2OP3 A;  4W4U A;  2B1M A;  4YYU A;  4XUI A;  3TNX A;  4YYV A;  3N3K A;  3DF0 A;  3ZUA A;  2PRE A;  1ME3 A;  1STF E;  5EF4 A;  1AIM A;  3H8B A;  4YYS A;  3IMA A;  3GCB A;  3P5U A;  3K9M A;  3KSE A;  3MHS A;  1NB5 A;  1MHW A;  3PBH A;  1DEU A;  2CIO A;  1PPO A;  1PPD A;  2E02 A;  4YYR A;  4X6I A;  2NQD B;  2E00 A;  4KLB A;  3U8E A;  4MZO A;  2R9N A;  1F2C A;  1YK7 A;  2P0R A;  1PPN A;  2F1G A;  2AVW A;  2AU1 A;  3KW9 A;  1QOL A;  1QMY A;  1YT7 A;  2HD5 A;  2F7D A;  1TU6 A;  1KHP A;  1KFX L;  2G8J A;  4FJC A;  1GMY A;  1U9X A;  3RVV A;  1Y4H A;  4AXM A;  2R6N A;  4CDE B;  4CDC B;  2R9F A;  4BS5 A;  3PNR A;  4WA6 A;  3F75 A;  4XR7 A;  3I06 A;  3H89 A;  3QSD A;  1AYW A;  1CVZ A;  1JQP A;  2DC9 A;  1ZCM A;  2FT2 A;  2Y5B A;  2DCB A;  1MIR A;  3WXE A;  2FRA A;  2YJB A;  3O0U A;  2AYO A;  1FH0 A;  1NLJ A;  2XU3 A;  4CZW A;  1Y08 A;  2PNS A;  4I04 A;  3E1Z B;  4BSQ A;  1AYU A;  3OVZ A;  2XU5 A;  4HWY A;  7PCK A;  3LFY A;  1YVB A;  2PBH A;  3KWZ A;  5CVO B;  4MZS A;  3I3T A;  4PAD A;  2DCA A;  5J94 A;  2NQA A;  1U9Q X;  3ERV A;  2FYE A;  1AYV A;  5PAD A;  1PIP A;  3V6C A;  4BQV A;  4I07 A;  3BC3 A;  3O1G A;  4N79 A;  1M6D A;  2IPP B;  2B1N A;  4G54 A;  3BOW A;  4AXL A;  1NB3 A;  3NHE A;  3BPM A;  3IV2 A;  4OEL A;  1VJV A;  1QDQ A;  1SNK A;  1AU4 A;  1EWP A;  3HHI A;  4PI3 A;  1MEM A;  1SP4 B;  1PXV A;  1THE A;  3KWB X;  2ACT A;  1Q6K A;  1NL6 A;  1AU0 A;  1F2B A;  4YV8 A;  4MSX A;  2P7U A;  1EWM A;  4X6H A;  1EF7 A;  2Y6E A;  2FTD A;  4QRV A;  2FRQ A;  3WXF A;  2P86 A;  4BPV A;  4Q8H A;  1YAL A;  3OF8 A;  2XU1 A;  3KFQ A;  3BWK A;  1ICF A;  2WBF X;  2R9M A;  3KX1 A;  1CS8 A;  2GHU A;  2DCC A;  2HHN A;  5CHV A;  3CBK A;  2XU4 A;  2VHS A;  1DF0 A;  1MDW A;  4QH6 A;  1CV8 A;  1GLO A;  4PP1 A;  1PBH A;  4CDF B;  1U9W A;  3D6S A;  1BP4 A;  1KFU L;  9PAP A;  1EWL A;  4I05 A;  1F2A A;  5CHT A;  1K3B B;  1KXR A;  2YJ8 A;  2AUX A;  1ZIV A;  1TL9 A;  3IHP A;  1AU2 A;  8PCH A;  2DZZ A;  2G7Y A;  1X9Y A;  4FK5 A;  2C0Y A;  3KKU A;  3WXG A;  1XKG A;  2DJG B;  2FUD A;  2AIM A;  1BQI A;  2ARY A;  2YJC A;  5K16 A;  4P6G A;  2R9O A;  2DZY A;  2BDZ A;  2FQ9 A;  3CH2 X;  2AUZ A;  3QT4 A;  1GEC E;  5CVN B;  4BS6 A;  3HHA A;  3IOQ A;  4FIP A;  1IWD A;  1POP A;  3K8U A;  4ZUX U;  4W5B A;  3F5V A;  2DCD A;  2HH5 A;  2E01 A;  2PAD A;  3OVX A;  2DC6 A;  4N8W A;  4RY2 A;  1PCI A;  2HXZ A;  2OUL A;  2O6X A;  1BGO A;  4DMX A;  1U9V A;  1TLO A;  1PE6 A;  4PP2 E;  4CDD B;  3P5X A;  3OF9 A;  3RVX A;  2IBI A;  5F02 A;  1ITO A;  3V6E A;  3K24 A;  1AEC A;  1CB5 A;  3PW3 A;  4X6J A;  3USV A;  2GFO A;  1MS6 A;  1VSN A;  3BPF A;  3OIS A;  3H6S A;  3H7D A;  5EGW A;  1HUC B;  1F29 A;  2NQG A;  1CSB B;  2YJ9 A;  4DMY A;  2R9C A;  3C9E A;  3HD3 A;  6PAD A;  4K7C A;  1KHQ A;  3RVW A;  2H7J A;  1YK8 A;  3MOR A;  1MEG A;  1ME4 A;  4N4Z A;  2DC8 A;  3S3Q A;  1CJL A;  4QBB A;  1CTE A;  5JH3 A;  2YJ2 A;  3LXS A;  3PDF A;  1NPZ A;  3CH3 X;  1CPJ A;  2VHF A;  2OZ2 A;  1BY8 A;  4QRG A;  3M99 A;  1A6R A;  2FO5 A;  3IUT A;  3B79 A;  1ATK A;  2DJF B;  4OEM A;  1S4V A;  4W5C A;  5FPW A;  3HWN A;  1GCB A;  2AYN A;  4Q8G A;  1QXP A;  3MTN A;  4YYW A;  2CB5 A;  3H8C A;  3CBJ A;  3IEJ A;  3N3G A;  3S3R A;  5A24 A;  1O0E A;  2DC7 A;  1U5I A;  2AS8 A;  2G8E A;  3P5V A;  2NQI A;  1CQD A;  1NQC A;  4QRX A;  4YYQ A;  3QJ3 A;  1PAD A;  1EWO A;  3N4C A;  4YVA A;  2ATO A;  2G6D A;  2JQF R;  5JA7 A;  2E03 A; 
#chains in the Genus database with same CATH topology
 3OQC A;  4D8B A;  5CVM A;  2BDL A;  1PPP A;  3AI8 A;  4P6E A;  1AU3 A;  3BCN A;  2JQG R;  3MHH A;  3P5W A;  2OP3 A;  4W4U A;  2B1M A;  4YYU A;  4IP3 A;  4XUI A;  2DOS A;  3ZNH A;  4BOZ A;  3TNX A;  4YYV A;  3N3K A;  3DF0 A;  3E9S A;  3ZUA A;  2PRE A;  1ME3 A;  1STF E;  4REZ A;  5EF4 A;  1AIM A;  1YZB A;  3H8B A;  4YYS A;  3IMA A;  3GCB A;  3P5U A;  3K9M A;  3KSE A;  3MHS A;  1NB5 A;  3PHU A;  1MHW A;  3PBH A;  1DEU A;  3IFU A;  2CIO A;  1PPO A;  4ZTB A;  1PPD A;  2E02 A;  4YYR A;  4X6I A;  2NQD B;  2E00 A;  4BOU A;  4KLB A;  3U8E A;  4MZO A;  2R9N A;  1F2C A;  1YK7 A;  2P0R A;  1PPN A;  2F1G A;  2AVW A;  2AU1 A;  3KW9 A;  1QOL A;  1QMY A;  3TMP A;  1YT7 A;  4BOQ A;  2HD5 A;  2F7D A;  1TU6 A;  1KHP A;  1KFX L;  2G8J A;  4WUR A;  4FJC A;  2HWK A;  1GMY A;  4IUM A;  1U9X A;  3RVV A;  1Y4H A;  2BTW A;  4AXM A;  2R6N A;  4CDE B;  4CDC B;  2R9F A;  4BS5 A;  3PNR A;  4WA6 A;  3F75 A;  4XR7 A;  1PVJ A;  3I06 A;  2AGA A;  3H89 A;  3QSD A;  1AYW A;  1CVZ A;  1JQP A;  2DC9 A;  1ZCM A;  2FT2 A;  2Y5B A;  2DCB A;  3PSE A;  4PT5 A;  1MIR A;  3WXE A;  2FRA A;  2YJB A;  3O0U A;  1UKF A;  2AYO A;  1FH0 A;  1NLJ A;  2XU3 A;  4CZW A;  1Y08 A;  2PNS A;  4I04 A;  3E1Z B;  4BSQ A;  4R3D A;  1AYU A;  3OVZ A;  4RF1 A;  2XU5 A;  4HWY A;  7PCK A;  3LFY A;  3O65 A;  1YVB A;  2PBH A;  3KWZ A;  5CVO B;  4MZS A;  3I3T A;  4PAD A;  2DCA A;  4OVZ B;  5J94 A;  3C0R A;  2NQA A;  1U9Q X;  5EZQ A;  3W31 A;  3ERV A;  2FYE A;  1AYV A;  5PAD A;  1PIP A;  3V6C A;  4BQV A;  4I07 A;  3BC3 A;  3O1G A;  4N79 A;  1M6D A;  2IPP B;  2B1N A;  4G54 A;  3BOW A;  4AXL A;  1NB3 A;  3NHE A;  3BPM A;  3IV2 A;  4OEL A;  2FE8 A;  1VJV A;  1QDQ A;  1SNK A;  1AU4 A;  1EWP A;  3HHI A;  4PI3 A;  1MEM A;  1SP4 B;  1PXV A;  1THE A;  3MTV A;  2BU3 A;  4M0W A;  3KWB X;  2ACT A;  1Q6K A;  1NL6 A;  1AU0 A;  1F2B A;  4YV8 A;  4MSX A;  2P7U A;  3PRM A;  5E6J A;  1EWM A;  4X6H A;  1EF7 A;  2Y6E A;  2FTD A;  4QRV A;  2Z84 A;  2FRQ A;  4D8E A;  2J7Q C;  3WXF A;  2P86 A;  4BPV A;  4Q8H A;  1YAL A;  3OF8 A;  2BTW B;  2XU1 A;  3MJ5 A;  3KFQ A;  3BBA A;  3BWK A;  4XZX A;  1ICF A;  2WBF X;  3RNV A;  2R9M A;  3KX1 A;  1CS8 A;  2GHU A;  2DCC A;  3B21 A;  2HHN A;  5CHV A;  3CBK A;  2XU4 A;  2VHS A;  1DF0 A;  1MDW A;  4QH6 A;  1CV8 A;  1GLO A;  4PP1 A;  3BB7 A;  1PBH A;  4CDF B;  1U9W A;  3D6S A;  1BP4 A;  1KFU L;  4HXD B;  9PAP A;  1EWL A;  4I05 A;  1F2A A;  4RF0 A;  5CHT A;  1K3B B;  1KXR A;  2YJ8 A;  4P16 A;  2AUX A;  1ZIV A;  1TL9 A;  3IHP A;  1AU2 A;  8PCH A;  2DZZ A;  2G7Y A;  1X9Y A;  4GUA A;  4FK5 A;  2C0Y A;  3KKU A;  3WXG A;  1XKG A;  2DJG B;  2FUD A;  2AIM A;  1BQI A;  2ARY A;  2YJC A;  4MM3 B;  5K16 A;  4P6G A;  2R9O A;  2DZY A;  2BDZ A;  2FQ9 A;  3CH2 X;  4MI7 A;  2AUZ A;  3QT4 A;  1GEC E;  5CVN B;  4BS6 A;  3HHA A;  3IOQ A;  4FIP A;  1IWD A;  3K8U A;  1POP A;  4ZUX U;  4W5B A;  3F5V A;  2DCD A;  2HH5 A;  2E01 A;  2PAD A;  3OVX A;  2DC6 A;  4N8W A;  4RY2 A;  4OW0 A;  1PCI A;  2HXZ A;  2OUL A;  2O6X A;  3TRK A;  1BGO A;  4DMX A;  1U9V A;  1TLO A;  2UZJ A;  1PE6 A;  4PP2 E;  1DKI A;  4CDD B;  4D8I A;  3P5X A;  3OF9 A;  4OVZ A;  3RVX A;  2IBI A;  5F02 A;  1ITO A;  3V6E A;  3K24 A;  1AEC A;  1CB5 A;  3PW3 A;  4X6J A;  3USV A;  2GFO A;  1MS6 A;  1VSN A;  3BPF A;  2JRI A;  3OIS A;  3H6S A;  3H7D A;  5EGW A;  1HUC B;  1F29 A;  2NQG A;  1CSB B;  2YJ9 A;  4DMY A;  3MP2 A;  2R9C A;  3C9E A;  3PT2 A;  3HD3 A;  6PAD A;  5EZS A;  4K7C A;  1KHQ A;  3RVW A;  4RKX A;  3PRP A;  2H7J A;  1YK8 A;  3MOR A;  1MEG A;  1ME4 A;  4N4Z A;  2DC8 A;  3S3Q A;  1CJL A;  4QBB A;  1CTE A;  5JH3 A;  2YJ2 A;  3LXS A;  3PDF A;  1NPZ A;  3CH3 X;  1CPJ A;  2VHF A;  2OZ2 A;  1BY8 A;  3PHW A;  5KO3 A;  4QRG A;  4BOS A;  3M99 A;  1A6R A;  2FO5 A;  3IUT A;  3B79 A;  4A5U A;  1ATK A;  5JZE A;  2DJF B;  4OEM A;  1S4V A;  4W5C A;  5FPW A;  4BOP A;  3HWN A;  1GCB A;  2AYN A;  4Q8G A;  1QXP A;  3MTN A;  4YYW A;  2CB5 A;  3H8C A;  3CBJ A;  3IEJ A;  3N3G A;  3W30 A;  3S3R A;  5A24 A;  1O0E A;  2DC7 A;  1U5I A;  3BY4 A;  2AS8 A;  2G8E A;  3P5V A;  2NQI A;  1CQD A;  1NQC A;  4QRX A;  2J7Q A;  3PHX A;  4YYQ A;  3QJ3 A;  2JTC A;  1PAD A;  1EWO A;  3N4C A;  4RNA A;  4YVA A;  2ATO A;  2G6D A;  2JQF R;  5JA7 A;  2E03 A; 
#chains in the Genus database with same CATH homology
 5CVM A;  2BDL A;  1PPP A;  3AI8 A;  4P6E A;  1AU3 A;  3BCN A;  2JQG R;  3MHH A;  3P5W A;  2OP3 A;  4W4U A;  2B1M A;  4YYU A;  4XUI A;  3TNX A;  4YYV A;  3N3K A;  3DF0 A;  3ZUA A;  2PRE A;  1ME3 A;  1STF E;  5EF4 A;  1AIM A;  3H8B A;  4YYS A;  3IMA A;  3GCB A;  1W6F A;  3P5U A;  3K9M A;  3KSE A;  3MHS A;  1NB5 A;  1MHW A;  3PBH A;  1DEU A;  2CIO A;  1PPO A;  1PPD A;  2E02 A;  4YYR A;  4X6I A;  2NQD B;  2E00 A;  4KLB A;  3U8E A;  4MZO A;  2R9N A;  1F2C A;  1YK7 A;  2P0R A;  1PPN A;  2F1G A;  2AVW A;  2AU1 A;  3KW9 A;  1QOL A;  1QMY A;  1YT7 A;  2HD5 A;  2F7D A;  1TU6 A;  1KHP A;  1KFX L;  2G8J A;  4FJC A;  1GMY A;  1U9X A;  3RVV A;  1Y4H A;  4AXM A;  2R6N A;  4CDE B;  4CDC B;  2R9F A;  4BS5 A;  3PNR A;  4WA6 A;  3F75 A;  4XR7 A;  3I06 A;  3H89 A;  3QSD A;  1AYW A;  1CVZ A;  1JQP A;  2DC9 A;  1ZCM A;  2FT2 A;  2Y5B A;  2DCB A;  1MIR A;  3WXE A;  2FRA A;  2YJB A;  3O0U A;  4NV8 A;  2AYO A;  1FH0 A;  1NLJ A;  2XU3 A;  4CZW A;  1Y08 A;  2PNS A;  4I04 A;  3E1Z B;  4BSQ A;  1AYU A;  3OVZ A;  2XU5 A;  4HWY A;  7PCK A;  3LFY A;  1YVB A;  2PBH A;  3KWZ A;  5CVO B;  4MZS A;  3I3T A;  4PAD A;  2DCA A;  5J94 A;  2NQA A;  1U9Q X;  3ERV A;  2FYE A;  1AYV A;  5PAD A;  1PIP A;  3V6C A;  4BQV A;  4I07 A;  3BC3 A;  3O1G A;  4N79 A;  1M6D A;  2IPP B;  2B1N A;  4G54 A;  3BOW A;  4AXL A;  1NB3 A;  3NHE A;  3BPM A;  3IV2 A;  4OEL A;  1VJV A;  1QDQ A;  1SNK A;  1AU4 A;  1EWP A;  3HHI A;  4PI3 A;  1MEM A;  1SP4 B;  1PXV A;  1THE A;  3KWB X;  2ACT A;  1Q6K A;  1NL6 A;  3LTW A;  1AU0 A;  1F2B A;  4YV8 A;  4MSX A;  2P7U A;  1EWM A;  4X6H A;  1EF7 A;  2Y6E A;  2FTD A;  4QRV A;  2FRQ A;  3WXF A;  2P86 A;  4BPV A;  4Q8H A;  1YAL A;  3OF8 A;  2XU1 A;  3KFQ A;  3BWK A;  1ICF A;  2WBF X;  2R9M A;  3KX1 A;  1CS8 A;  2GHU A;  2DCC A;  2HHN A;  5CHV A;  3CBK A;  2XU4 A;  2BSZ A;  2VHS A;  1DF0 A;  1MDW A;  4QH6 A;  1CV8 A;  1GLO A;  4PP1 A;  1PBH A;  4CDF B;  1U9W A;  3D6S A;  1BP4 A;  1KFU L;  9PAP A;  1EWL A;  4I05 A;  1F2A A;  5CHT A;  4GUZ A;  1K3B B;  1KXR A;  2YJ8 A;  2AUX A;  1ZIV A;  1TL9 A;  3IHP A;  1AU2 A;  8PCH A;  2DZZ A;  2G7Y A;  1X9Y A;  4FK5 A;  2C0Y A;  3KKU A;  3WXG A;  1XKG A;  2DJG B;  2FUD A;  2VFB A;  2AIM A;  1BQI A;  2ARY A;  2YJC A;  5K16 A;  4P6G A;  2R9O A;  2DZY A;  2BDZ A;  2FQ9 A;  3CH2 X;  2AUZ A;  3QT4 A;  1GEC E;  5CVN B;  4BS6 A;  3HHA A;  3IOQ A;  4FIP A;  1IWD A;  3K8U A;  1POP A;  4ZUX U;  4W5B A;  3F5V A;  2DCD A;  2HH5 A;  2E01 A;  2PAD A;  3OVX A;  2DC6 A;  4N8W A;  4RY2 A;  1PCI A;  2HXZ A;  2OUL A;  2O6X A;  1BGO A;  4DMX A;  1U9V A;  1TLO A;  1PE6 A;  4PP2 E;  4CDD B;  3P5X A;  3OF9 A;  3RVX A;  2IBI A;  5F02 A;  1ITO A;  3V6E A;  1GX3 A;  3K24 A;  1AEC A;  1CB5 A;  3PW3 A;  4X6J A;  3USV A;  2GFO A;  1MS6 A;  1VSN A;  3BPF A;  3OIS A;  3H6S A;  3H7D A;  5EGW A;  4B55 A;  1HUC B;  1F29 A;  2NQG A;  1CSB B;  2YJ9 A;  4DMY A;  1W5R A;  2R9C A;  3C9E A;  3HD3 A;  6PAD A;  4K7C A;  1KHQ A;  3RVW A;  2H7J A;  1YK8 A;  3MOR A;  1MEG A;  1ME4 A;  4N4Z A;  2DC8 A;  3S3Q A;  1CJL A;  4QBB A;  1CTE A;  5JH3 A;  2YJ2 A;  3LXS A;  3PDF A;  1NPZ A;  3CH3 X;  1CPJ A;  2VHF A;  2OZ2 A;  1BY8 A;  4QRG A;  3M99 A;  1A6R A;  2FO5 A;  3IUT A;  3B79 A;  1ATK A;  2DJF B;  1E2T A;  4OEM A;  1S4V A;  3D9W A;  4BGF A;  4W5C A;  5FPW A;  3HWN A;  1GCB A;  2VFC A;  1W4T A;  2AYN A;  4Q8G A;  1QXP A;  3MTN A;  4YYW A;  2CB5 A;  3H8C A;  3CBJ A;  4C5P A;  3IEJ A;  3N3G A;  3S3R A;  5A24 A;  1O0E A;  2DC7 A;  1U5I A;  2AS8 A;  2G8E A;  3P5V A;  2NQI A;  1CQD A;  1NQC A;  4QRX A;  4YYQ A;  3QJ3 A;  1PAD A;  4NV7 A;  1EWO A;  3N4C A;  4YVA A;  2ATO A;  2G6D A;  2JQF R;  5JA7 A;  2E03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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