3H89A

A combined crystallographic and molecular dynamics study of cathepsin-l retro-binding inhibitors(compound 4)
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
220
structure length
215
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A combined crystallographic and molecular dynamics study of cathepsin L retrobinding inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin L1
total genus 69
structure length 215
sequence length 220
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2009-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3h89A00
3AI8A 1NB3A 1EWLA 1CV8A 1GMYA 3CH2X 1GLOA 1Y08A 1CTEA 2NQIA 1ME3A 3PDFA 4YVAA 4AXMA 2VHFA 1NQCA 3U8EA 2XU3A 1YK8A 1MHWA 4G54A 5PADA 5K16A 4BS5A 5EF4A 6PADA 3H8BA 1CVZA 2E00A 3MHSA 4YYSA 3MHHA 2BDLA 3H8CA 5CVNB 2Y5BA 2OP3A 2YJBA 2R9OA 1EWMA 5JA7A 2R9NA 1NL6A 1MS6A 2JQFR 1F2AA 2HD5A 2YJ8A 4Q8HA 4BS6A 4W5BA 1HUCB 1AIMA 2R9CA 2FQ9A 3BC3A 2B1NA 2PADA 4I07A 1TL9A 3H89A 2JQGR 3BCNA 2DC8A 5CVOB 1M6DA 1VJVA 3IV2A 1AU0A 1YK7A 1MEMA 2DCAA 3RVVA 2NQGA 1F2CA 3KW9A 3IHPA 3MTNA 2ACTA 2P0RA 4RY2A 1CPJA 1AYWA 1CSBB 3ZUAA 3OVZA 3KSEA 2AIMA 2CIOA 4FJCA 1AU3A 1K3BB 1GECE 1SP4B 2DCBA 1THEA 1EWOA 3F5VA 4N79A 1NPZA 4YYQA 4XR7A 3HD3A 4ZUXU 3IMAA 2VHSA 4YV8A 3DF0A 4BQVA 3V6EA 1ZCMA 2NQDB 3K8UA 4P6GA 1PADA 1ITOA 3C9EA 1S4VA 4DMXA 3QJ3A 3N4CA 2E02A 3OF8A 7PCKA 4N8WA 1XKGA 2BDZA 3O0UA 1GCBA 3P5WA 2E03A 4CDCB 2GFOA 3PW3A 1DF0A 4YYRA 2P7UA 4WA6A 3HHIA 1TU6A 1CS8A 2XU5A 3K9MA 1PBHA 1BY8A 1PPPA 1MDWA 4X6JA 2DJGB 2R6NA 1PE6A 1KFXL 3MORA 4PI3A 5A24A 2DC7A 2GHUA 1U9WA 1AU4A 1U9VA 1CQDA 3RVWA 2C0YA 1ICFA 1TLOA 3I3TA 1VSNA 1U9QX 4AXLA 3PBHA 4PADA 5CHVA 1PXVA 4MZOA 3BPFA 4X6IA 4QH6A 2CB5A 2XU4A 4YYWA 1X9YA 2FYEA 1FH0A 4BPVA 2DC9A 2OZ2A 4Q8GA 3P5UA 3PNRA 2AU1A 2OULA 4QRVA 4MSXA 2F7DA 1ATKA 2R9FA 3P5VA 1KXRA 1QDQA 4I04A 4QRGA 1DEUA 3P5XA 1U5IA 4P6EA 5FPWA 4YYVA 2AUXA 3ERVA 1POPA 2DZYA 1YALA 4CDDB 3KKUA 4W5CA 2G6DA 1ZIVA 2YJCA 4CDEB 3BWKA 3RVXA 2NQAA 1PIPA 4N4ZA 1Q6KA 2DCCA 2E01A 5CHTA 3WXGA 2ATOA 1JQPA 3QSDA 4OEMA 8PCHA 5J94A 2XU1A 3M99A 3K24A 2DJFB 2PREA 1BQIA 4PP2E 3KWZA 3QT4A 2FRAA 1BP4A 5EGWA 3S3QA 1PPNA 2H7JA 1MEGA 4OELA 1QOLA 2DZZA 2DCDA 1KFUL 4K7CA 2AYNA 1KHPA 4MZSA 2IBIA 4YYUA 3OISA 3N3KA 2G8JA 4QRXA 3D6SA 2HH5A 2R9MA 3USVA 1PPDA 3TNXA 2G8EA 1AU2A 3KX1A 4FK5A 2FO5A 1YVBA 2AYOA 1AYUA 3H7DA 3IUTA 1Y4HA 1PPOA 1QXPA 4QBBA 2O6XA 3HWNA 3N3GA 1MIRA 2B1MA 3F75A 2F1GA 3OF9A 3HHAA 3S3RA 5CVMA 3I06A 2FRQA 2DC6A 3CH3X 3IEJA 2G7YA 5JH3A 1YT7A 2YJ2A 3WXFA 9PAPA 3CBKA 1ME4A 3E1ZB 2FUDA 1CJLA 3GCBA 1EWPA 3IOQA 3NHEA 2AS8A 4DMYA 2P86A 1AECA 4BSQA 3KWBX 2IPPB 2WBFX 3B79A 5F02A 3V6CA 2PNSA 2FTDA 3WXEA 2HXZA 4XUIA 1U9XA 1EF7A 4CZWA 1KHQA 3BOWA 2ARYA 3KFQA 3OVXA 4W4UA 1F2BA 1AYVA 2Y6EA 2PBHA 1CB5A 3H6SA 3LXSA 1NB5A 3LFYA 2AUZA 2HHNA 1QMYA 4I05A 3BPMA 4CDFB 4HWYA 1NLJA 1F29A 1STFE 1O0EA 1A6RA 1BGOA 2YJ9A 1PCIA 4KLBA 2AVWA 1IWDA 3O1GA 3CBJA 4X6HA 4PP1A 1SNKA 4FIPA 2FT2A
chains in the Genus database with same CATH superfamily
1YZBA 3AI8A 1NB3A 1EWLA 1CV8A 1GMYA 3O65A 3CH2X 1GLOA 1Y08A 4PT5A 1CTEA 2NQIA 1ME3A 3W31A 3PDFA 4YVAA 4AXMA 2VHFA 4RKXA 1NQCA 3U8EA 2XU3A 1YK8A 1MHWA 4G54A 5PADA 5K16A 4BS5A 5EF4A 6PADA 3C0RA 3H8BA 1CVZA 2E00A 3MJ5A 3MHSA 4YYSA 3MHHA 2BDLA 5EZQA 3H8CA 5CVNB 2Y5BA 2OP3A 2YJBA 2R9OA 1EWMA 5JA7A 2R9NA 1NL6A 1MS6A 2JQFR 1F2AA 2HD5A 4R3DA 2YJ8A 3BB7A 4GUAA 3E9SA 4Q8HA 4BS6A 4W5BA 1HUCB 1AIMA 3OQCA 2R9CA 2FQ9A 3BC3A 2B1NA 2PADA 4I07A 1TL9A 3H89A 2JQGR 3BCNA 3MTVA 2DC8A 5CVOB 1M6DA 1VJVA 3IV2A 1AU0A 1UKFA 1MEMA 1YK7A 2DCAA 3RVVA 2NQGA 1F2CA 3KW9A 4WURA 3IHPA 4P16A 3MTNA 2ACTA 2P0RA 4RY2A 1CPJA 1AYWA 1CSBB 3ZUAA 3OVZA 3KSEA 2AIMA 2CIOA 4FJCA 1AU3A 1K3BB 1GECE 4M0WA 1SP4B 2DCBA 4BOUA 3B21A 1THEA 1EWOA 2JRIA 3F5VA 4N79A 1NPZA 4YYQA 4XR7A 3HD3A 5E6JA 4REZA 4ZUXU 3IMAA 2VHSA 4YV8A 3DF0A 4BQVA 3V6EA 1ZCMA 2NQDB 3K8UA 2FE8A 3PRMA 4P6GA 1PADA 1ITOA 3C9EA 1S4VA 4DMXA 3QJ3A 3N4CA 2E02A 3OF8A 7PCKA 4N8WA 1XKGA 2BDZA 3O0UA 3ZNHA 1GCBA 3P5WA 2E03A 5JZEA 3BBAA 4CDCB 2GFOA 3PW3A 1DF0A 4YYRA 2P7UA 4WA6A 3HHIA 3PSEA 1TU6A 1CS8A 2XU5A 3K9MA 1PBHA 1BY8A 3RNVA 1PPPA 4BOPA 1MDWA 4X6JA 3PHXA 2DJGB 2R6NA 1PE6A 1KFXL 3MORA 4PI3A 5A24A 2DC7A 2UZJA 2GHUA 1U9WA 1AU4A 3MP2A 1U9VA 1CQDA 3RVWA 2C0YA 4D8IA 1ICFA 3I3TA 1TLOA 1VSNA 1U9QX 4AXLA 3PBHA 4PADA 5CHVA 1PXVA 4MZOA 3BPFA 3W30A 4X6IA 4QH6A 2CB5A 2XU4A 4YYWA 4MM3B 1X9YA 2FYEA 1FH0A 4BPVA 4OW0A 2DC9A 2OZ2A 4Q8GA 3P5UA 4BOSA 3PNRA 2AU1A 2OULA 4QRVA 4MSXA 2F7DA 1ATKA 3IFUA 2R9FA 3P5VA 1KXRA 3TRKA 4RNAA 1QDQA 4I04A 4RF1A 4QRGA 1DEUA 3P5XA 1U5IA 4P6EA 5FPWA 4YYVA 2AUXA 3ERVA 1POPA 2DZYA 1YALA 4CDDB 3KKUA 4W5CA 2G6DA 1ZIVA 2YJCA 4CDEB 3BWKA 3RVXA 4XZXA 4HXDB 2NQAA 1PIPA 4N4ZA 1Q6KA 2DCCA 2E01A 2DOSA 2BTWB 5CHTA 3WXGA 2ATOA 1JQPA 3QSDA 4OEMA 4OVZB 8PCHA 5J94A 2XU1A 4BOQA 3M99A 3K24A 4RF0A 2DJFB 2PREA 4IUMA 1BQIA 4PP2E 3PHUA 3KWZA 3QT4A 2FRAA 1BP4A 5EGWA 3S3QA 1PPNA 2H7JA 1MEGA 4OELA 1QOLA 2DZZA 2DCDA 1KFUL 4K7CA 2AYNA 4BOZA 5EZSA 2J7QA 3PHWA 1KHPA 4MZSA 2IBIA 3TMPA 3OISA 3N3KA 4YYUA 2G8JA 4QRXA 3D6SA 2HH5A 2R9MA 3USVA 1PPDA 3TNXA 2G8EA 1AU2A 3KX1A 4FK5A 2FO5A 1YVBA 2AYOA 1AYUA 3H7DA 3IUTA 1Y4HA 1PPOA 1QXPA 4QBBA 2O6XA 3HWNA 5KO3A 3N3GA 1MIRA 2B1MA 3F75A 2F1GA 4IP3A 2Z84A 3OF9A 3HHAA 3S3RA 5CVMA 3I06A 2FRQA 2DC6A 2BU3A 2JTCA 3CH3X 2J7QC 3IEJA 4A5UA 2G7YA 3PT2A 1YT7A 5JH3A 2YJ2A 3WXFA 9PAPA 3CBKA 1ME4A 3E1ZB 2FUDA 1CJLA 3GCBA 1EWPA 3IOQA 3NHEA 2AS8A 4DMYA 2P86A 1AECA 4BSQA 3KWBX 2IPPB 2WBFX 3B79A 5F02A 3V6CA 4ZTBA 2PNSA 2FTDA 3WXEA 1PVJA 4D8EA 2HXZA 4MI7A 4XUIA 1U9XA 1EF7A 4CZWA 3BY4A 1KHQA 4D8BA 3BOWA 2BTWA 2ARYA 3KFQA 3OVXA 4W4UA 3PRPA 1F2BA 4OVZA 1AYVA 2Y6EA 2PBHA 1CB5A 3H6SA 3LXSA 1NB5A 3LFYA 2AUZA 2HHNA 1QMYA 4I05A 3BPMA 4CDFB 4HWYA 1DKIA 1NLJA 1F29A 1STFE 2HWKA 1O0EA 1A6RA 1BGOA 2YJ9A 1PCIA 4KLBA 2AVWA 1IWDA 3O1GA 3CBJA 4X6HA 2AGAA 4PP1A 1SNKA 4FIPA 2FT2A
chains in the Genus database with same CATH topology
3AI8A 1NB3A 1EWLA 1CV8A 1GMYA 3CH2X 1GLOA 1Y08A 1CTEA 2NQIA 1ME3A 3PDFA 4YVAA 4AXMA 2VHFA 1NQCA 3U8EA 2XU3A 1YK8A 1MHWA 4G54A 5PADA 5K16A 4BS5A 5EF4A 6PADA 4GUZA 3H8BA 1CVZA 2E00A 3MHSA 4YYSA 3MHHA 2BDLA 3H8CA 5CVNB 2Y5BA 2OP3A 2YJBA 2R9OA 1EWMA 5JA7A 2R9NA 1NL6A 1MS6A 2JQFR 1F2AA 2HD5A 2YJ8A 4NV7A 4Q8HA 4BS6A 4W5BA 1HUCB 1AIMA 2R9CA 2FQ9A 4B55A 3BC3A 2B1NA 2PADA 4I07A 1TL9A 3H89A 2JQGR 3BCNA 2DC8A 5CVOB 1M6DA 1VJVA 3IV2A 1AU0A 1YK7A 1MEMA 2DCAA 3RVVA 2NQGA 1F2CA 3KW9A 3IHPA 3MTNA 2ACTA 2P0RA 4RY2A 1CPJA 1AYWA 1CSBB 3ZUAA 3OVZA 3KSEA 2AIMA 2CIOA 4FJCA 1AU3A 1K3BB 1GECE 1SP4B 2DCBA 1THEA 1EWOA 3F5VA 4N79A 1NPZA 4YYQA 4XR7A 3HD3A 1E2TA 4ZUXU 3IMAA 2VHSA 4YV8A 3DF0A 4BQVA 3V6EA 1ZCMA 2NQDB 3K8UA 4P6GA 1PADA 1ITOA 3C9EA 1S4VA 4DMXA 3QJ3A 4NV8A 3N4CA 2E02A 4BGFA 3OF8A 7PCKA 4N8WA 1XKGA 2BDZA 3O0UA 1GCBA 3P5WA 2E03A 4CDCB 2GFOA 3PW3A 1DF0A 4YYRA 2P7UA 4WA6A 3HHIA 1TU6A 1CS8A 2XU5A 3K9MA 1PBHA 1BY8A 1PPPA 1MDWA 4X6JA 2DJGB 2R6NA 3D9WA 1PE6A 1KFXL 3MORA 4C5PA 4PI3A 5A24A 2DC7A 2GHUA 1U9WA 1AU4A 1U9VA 1CQDA 3RVWA 1W4TA 2C0YA 1ICFA 1TLOA 3I3TA 1VSNA 1U9QX 4AXLA 3PBHA 4PADA 5CHVA 1PXVA 4MZOA 3BPFA 4X6IA 4QH6A 2CB5A 2XU4A 4YYWA 1X9YA 2FYEA 1FH0A 4BPVA 2DC9A 2OZ2A 4Q8GA 3P5UA 3PNRA 2AU1A 2OULA 4QRVA 4MSXA 1W5RA 2F7DA 2VFCA 1ATKA 2R9FA 3P5VA 1KXRA 1QDQA 4I04A 4QRGA 1DEUA 3P5XA 1U5IA 4P6EA 5FPWA 3LTWA 4YYVA 2AUXA 3ERVA 1POPA 2DZYA 1YALA 4CDDB 3KKUA 4W5CA 2G6DA 1ZIVA 2YJCA 2VFBA 4CDEB 3BWKA 3RVXA 2NQAA 1PIPA 4N4ZA 1Q6KA 2DCCA 2E01A 5CHTA 3WXGA 2ATOA 1JQPA 3QSDA 4OEMA 8PCHA 5J94A 2XU1A 3M99A 3K24A 2DJFB 2PREA 1BQIA 4PP2E 3KWZA 3QT4A 2FRAA 1BP4A 5EGWA 3S3QA 1PPNA 2H7JA 1MEGA 4OELA 1QOLA 2DZZA 2DCDA 1KFUL 4K7CA 2AYNA 1KHPA 4MZSA 2IBIA 4YYUA 3OISA 3N3KA 2G8JA 4QRXA 3D6SA 2HH5A 2R9MA 1GX3A 3USVA 1PPDA 3TNXA 2G8EA 1AU2A 3KX1A 4FK5A 2FO5A 1YVBA 2AYOA 1AYUA 3H7DA 3IUTA 1Y4HA 1PPOA 1QXPA 4QBBA 2O6XA 3HWNA 3N3GA 1MIRA 2B1MA 3F75A 2F1GA 2BSZA 3OF9A 3HHAA 3S3RA 5CVMA 3I06A 2FRQA 2DC6A 3CH3X 3IEJA 2G7YA 5JH3A 1YT7A 2YJ2A 3WXFA 9PAPA 3CBKA 1ME4A 3E1ZB 2FUDA 1CJLA 3GCBA 1EWPA 3IOQA 3NHEA 2AS8A 4DMYA 2P86A 1AECA 4BSQA 3KWBX 2IPPB 2WBFX 3B79A 5F02A 3V6CA 2PNSA 2FTDA 3WXEA 2HXZA 1W6FA 4XUIA 1U9XA 1EF7A 4CZWA 1KHQA 3BOWA 2ARYA 3KFQA 3OVXA 4W4UA 1F2BA 1AYVA 2Y6EA 2PBHA 1CB5A 3H6SA 3LXSA 1NB5A 3LFYA 2AUZA 2HHNA 1QMYA 4I05A 3BPMA 4CDFB 4HWYA 1NLJA 1F29A 1STFE 1O0EA 1A6RA 1BGOA 2YJ9A 1PCIA 4KLBA 2AVWA 1IWDA 3O1GA 3CBJA 4X6HA 4PP1A 1SNKA 4FIPA 2FT2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AI8 A;  1NB3 A;  1EWL A;  1CV8 A;  1GMY A;  3CH2 X;  1GLO A;  1Y08 A;  1CTE A;  2NQI A;  1ME3 A;  3PDF A;  4YVA A;  4AXM A;  2VHF A;  1NQC A;  3U8E A;  2XU3 A;  1YK8 A;  1MHW A;  4G54 A;  5PAD A;  5K16 A;  4BS5 A;  5EF4 A;  6PAD A;  3H8B A;  1CVZ A;  2E00 A;  3MHS A;  4YYS A;  3MHH A;  2BDL A;  3H8C A;  5CVN B;  2Y5B A;  2OP3 A;  2YJB A;  2R9O A;  1EWM A;  5JA7 A;  2R9N A;  1NL6 A;  1MS6 A;  2JQF R;  1F2A A;  2HD5 A;  2YJ8 A;  4Q8H A;  4BS6 A;  4W5B A;  1HUC B;  1AIM A;  2R9C A;  2FQ9 A;  3BC3 A;  2B1N A;  2PAD A;  4I07 A;  1TL9 A;  3H89 A;  2JQG R;  3BCN A;  2DC8 A;  5CVO B;  1M6D A;  1VJV A;  3IV2 A;  1AU0 A;  1YK7 A;  1MEM A;  2DCA A;  3RVV A;  2NQG A;  1F2C A;  3KW9 A;  3IHP A;  3MTN A;  2ACT A;  2P0R A;  4RY2 A;  1CPJ A;  1AYW A;  1CSB B;  3ZUA A;  3OVZ A;  3KSE A;  2AIM A;  2CIO A;  4FJC A;  1AU3 A;  1K3B B;  1GEC E;  1SP4 B;  2DCB A;  1THE A;  1EWO A;  3F5V A;  4N79 A;  1NPZ A;  4YYQ A;  4XR7 A;  3HD3 A;  4ZUX U;  3IMA A;  2VHS A;  4YV8 A;  3DF0 A;  4BQV A;  3V6E A;  1ZCM A;  2NQD B;  3K8U A;  4P6G A;  1PAD A;  1ITO A;  3C9E A;  1S4V A;  4DMX A;  3QJ3 A;  3N4C A;  2E02 A;  3OF8 A;  7PCK A;  4N8W A;  1XKG A;  2BDZ A;  3O0U A;  1GCB A;  3P5W A;  2E03 A;  4CDC B;  2GFO A;  3PW3 A;  1DF0 A;  4YYR A;  2P7U A;  4WA6 A;  3HHI A;  1TU6 A;  1CS8 A;  2XU5 A;  3K9M A;  1PBH A;  1BY8 A;  1PPP A;  1MDW A;  4X6J A;  2DJG B;  2R6N A;  1PE6 A;  1KFX L;  3MOR A;  4PI3 A;  5A24 A;  2DC7 A;  2GHU A;  1U9W A;  1AU4 A;  1U9V A;  1CQD A;  3RVW A;  2C0Y A;  1ICF A;  1TLO A;  3I3T A;  1VSN A;  1U9Q X;  4AXL A;  3PBH A;  4PAD A;  5CHV A;  1PXV A;  4MZO A;  3BPF A;  4X6I A;  4QH6 A;  2CB5 A;  2XU4 A;  4YYW A;  1X9Y A;  2FYE A;  1FH0 A;  4BPV A;  2DC9 A;  2OZ2 A;  4Q8G A;  3P5U A;  3PNR A;  2AU1 A;  2OUL A;  4QRV A;  4MSX A;  2F7D A;  1ATK A;  2R9F A;  3P5V A;  1KXR A;  1QDQ A;  4I04 A;  4QRG A;  1DEU A;  3P5X A;  1U5I A;  4P6E A;  5FPW A;  4YYV A;  2AUX A;  3ERV A;  1POP A;  2DZY A;  1YAL A;  4CDD B;  3KKU A;  4W5C A;  2G6D A;  1ZIV A;  2YJC A;  4CDE B;  3BWK A;  3RVX A;  2NQA A;  1PIP A;  4N4Z A;  1Q6K A;  2DCC A;  2E01 A;  5CHT A;  3WXG A;  2ATO A;  1JQP A;  3QSD A;  4OEM A;  8PCH A;  5J94 A;  2XU1 A;  3M99 A;  3K24 A;  2DJF B;  2PRE A;  1BQI A;  4PP2 E;  3KWZ A;  3QT4 A;  2FRA A;  1BP4 A;  5EGW A;  3S3Q A;  1PPN A;  2H7J A;  1MEG A;  4OEL A;  1QOL A;  2DZZ A;  2DCD A;  1KFU L;  4K7C A;  2AYN A;  1KHP A;  4MZS A;  2IBI A;  4YYU A;  3OIS A;  3N3K A;  2G8J A;  4QRX A;  3D6S A;  2HH5 A;  2R9M A;  3USV A;  1PPD A;  3TNX A;  2G8E A;  1AU2 A;  3KX1 A;  4FK5 A;  2FO5 A;  1YVB A;  2AYO A;  1AYU A;  3H7D A;  3IUT A;  1Y4H A;  1PPO A;  1QXP A;  4QBB A;  2O6X A;  3HWN A;  3N3G A;  1MIR A;  2B1M A;  3F75 A;  2F1G A;  3OF9 A;  3HHA A;  3S3R A;  5CVM A;  3I06 A;  2FRQ A;  2DC6 A;  3CH3 X;  3IEJ A;  2G7Y A;  5JH3 A;  1YT7 A;  2YJ2 A;  3WXF A;  9PAP A;  3CBK A;  1ME4 A;  3E1Z B;  2FUD A;  1CJL A;  3GCB A;  1EWP A;  3IOQ A;  3NHE A;  2AS8 A;  4DMY A;  2P86 A;  1AEC A;  4BSQ A;  3KWB X;  2IPP B;  2WBF X;  3B79 A;  5F02 A;  3V6C A;  2PNS A;  2FTD A;  3WXE A;  2HXZ A;  4XUI A;  1U9X A;  1EF7 A;  4CZW A;  1KHQ A;  3BOW A;  2ARY A;  3KFQ A;  3OVX A;  4W4U A;  1F2B A;  1AYV A;  2Y6E A;  2PBH A;  1CB5 A;  3H6S A;  3LXS A;  1NB5 A;  3LFY A;  2AUZ A;  2HHN A;  1QMY A;  4I05 A;  3BPM A;  4CDF B;  4HWY A;  1NLJ A;  1F29 A;  1STF E;  1O0E A;  1A6R A;  1BGO A;  2YJ9 A;  1PCI A;  4KLB A;  2AVW A;  1IWD A;  3O1G A;  3CBJ A;  4X6H A;  4PP1 A;  1SNK A;  4FIP A;  2FT2 A; 
#chains in the Genus database with same CATH topology
 1YZB A;  3AI8 A;  1NB3 A;  1EWL A;  1CV8 A;  1GMY A;  3O65 A;  3CH2 X;  1GLO A;  1Y08 A;  4PT5 A;  1CTE A;  2NQI A;  1ME3 A;  3W31 A;  3PDF A;  4YVA A;  4AXM A;  2VHF A;  4RKX A;  1NQC A;  3U8E A;  2XU3 A;  1YK8 A;  1MHW A;  4G54 A;  5PAD A;  5K16 A;  4BS5 A;  5EF4 A;  6PAD A;  3C0R A;  3H8B A;  1CVZ A;  2E00 A;  3MJ5 A;  3MHS A;  4YYS A;  3MHH A;  2BDL A;  5EZQ A;  3H8C A;  5CVN B;  2Y5B A;  2OP3 A;  2YJB A;  2R9O A;  1EWM A;  5JA7 A;  2R9N A;  1NL6 A;  1MS6 A;  2JQF R;  1F2A A;  2HD5 A;  4R3D A;  2YJ8 A;  3BB7 A;  4GUA A;  3E9S A;  4Q8H A;  4BS6 A;  4W5B A;  1HUC B;  1AIM A;  3OQC A;  2R9C A;  2FQ9 A;  3BC3 A;  2B1N A;  2PAD A;  4I07 A;  1TL9 A;  3H89 A;  2JQG R;  3BCN A;  3MTV A;  2DC8 A;  5CVO B;  1M6D A;  1VJV A;  3IV2 A;  1AU0 A;  1UKF A;  1MEM A;  1YK7 A;  2DCA A;  3RVV A;  2NQG A;  1F2C A;  3KW9 A;  4WUR A;  3IHP A;  4P16 A;  3MTN A;  2ACT A;  2P0R A;  4RY2 A;  1CPJ A;  1AYW A;  1CSB B;  3ZUA A;  3OVZ A;  3KSE A;  2AIM A;  2CIO A;  4FJC A;  1AU3 A;  1K3B B;  1GEC E;  4M0W A;  1SP4 B;  2DCB A;  4BOU A;  3B21 A;  1THE A;  1EWO A;  2JRI A;  3F5V A;  4N79 A;  1NPZ A;  4YYQ A;  4XR7 A;  3HD3 A;  5E6J A;  4REZ A;  4ZUX U;  3IMA A;  2VHS A;  4YV8 A;  3DF0 A;  4BQV A;  3V6E A;  1ZCM A;  2NQD B;  3K8U A;  2FE8 A;  3PRM A;  4P6G A;  1PAD A;  1ITO A;  3C9E A;  1S4V A;  4DMX A;  3QJ3 A;  3N4C A;  2E02 A;  3OF8 A;  7PCK A;  4N8W A;  1XKG A;  2BDZ A;  3O0U A;  3ZNH A;  1GCB A;  3P5W A;  2E03 A;  5JZE A;  3BBA A;  4CDC B;  2GFO A;  3PW3 A;  1DF0 A;  4YYR A;  2P7U A;  4WA6 A;  3HHI A;  3PSE A;  1TU6 A;  1CS8 A;  2XU5 A;  3K9M A;  1PBH A;  1BY8 A;  3RNV A;  1PPP A;  4BOP A;  1MDW A;  4X6J A;  3PHX A;  2DJG B;  2R6N A;  1PE6 A;  1KFX L;  3MOR A;  4PI3 A;  5A24 A;  2DC7 A;  2UZJ A;  2GHU A;  1U9W A;  1AU4 A;  3MP2 A;  1U9V A;  1CQD A;  3RVW A;  2C0Y A;  4D8I A;  1ICF A;  3I3T A;  1TLO A;  1VSN A;  1U9Q X;  4AXL A;  3PBH A;  4PAD A;  5CHV A;  1PXV A;  4MZO A;  3BPF A;  3W30 A;  4X6I A;  4QH6 A;  2CB5 A;  2XU4 A;  4YYW A;  4MM3 B;  1X9Y A;  2FYE A;  1FH0 A;  4BPV A;  4OW0 A;  2DC9 A;  2OZ2 A;  4Q8G A;  3P5U A;  4BOS A;  3PNR A;  2AU1 A;  2OUL A;  4QRV A;  4MSX A;  2F7D A;  1ATK A;  3IFU A;  2R9F A;  3P5V A;  1KXR A;  3TRK A;  4RNA A;  1QDQ A;  4I04 A;  4RF1 A;  4QRG A;  1DEU A;  3P5X A;  1U5I A;  4P6E A;  5FPW A;  4YYV A;  2AUX A;  3ERV A;  1POP A;  2DZY A;  1YAL A;  4CDD B;  3KKU A;  4W5C A;  2G6D A;  1ZIV A;  2YJC A;  4CDE B;  3BWK A;  3RVX A;  4XZX A;  4HXD B;  2NQA A;  1PIP A;  4N4Z A;  1Q6K A;  2DCC A;  2E01 A;  2DOS A;  2BTW B;  5CHT A;  3WXG A;  2ATO A;  1JQP A;  3QSD A;  4OEM A;  4OVZ B;  8PCH A;  5J94 A;  2XU1 A;  4BOQ A;  3M99 A;  3K24 A;  4RF0 A;  2DJF B;  2PRE A;  4IUM A;  1BQI A;  4PP2 E;  3PHU A;  3KWZ A;  3QT4 A;  2FRA A;  1BP4 A;  5EGW A;  3S3Q A;  1PPN A;  2H7J A;  1MEG A;  4OEL A;  1QOL A;  2DZZ A;  2DCD A;  1KFU L;  4K7C A;  2AYN A;  4BOZ A;  5EZS A;  2J7Q A;  3PHW A;  1KHP A;  4MZS A;  2IBI A;  3TMP A;  3OIS A;  3N3K A;  4YYU A;  2G8J A;  4QRX A;  3D6S A;  2HH5 A;  2R9M A;  3USV A;  1PPD A;  3TNX A;  2G8E A;  1AU2 A;  3KX1 A;  4FK5 A;  2FO5 A;  1YVB A;  2AYO A;  1AYU A;  3H7D A;  3IUT A;  1Y4H A;  1PPO A;  1QXP A;  4QBB A;  2O6X A;  3HWN A;  5KO3 A;  3N3G A;  1MIR A;  2B1M A;  3F75 A;  2F1G A;  4IP3 A;  2Z84 A;  3OF9 A;  3HHA A;  3S3R A;  5CVM A;  3I06 A;  2FRQ A;  2DC6 A;  2BU3 A;  2JTC A;  3CH3 X;  2J7Q C;  3IEJ A;  4A5U A;  2G7Y A;  3PT2 A;  1YT7 A;  5JH3 A;  2YJ2 A;  3WXF A;  9PAP A;  3CBK A;  1ME4 A;  3E1Z B;  2FUD A;  1CJL A;  3GCB A;  1EWP A;  3IOQ A;  3NHE A;  2AS8 A;  4DMY A;  2P86 A;  1AEC A;  4BSQ A;  3KWB X;  2IPP B;  2WBF X;  3B79 A;  5F02 A;  3V6C A;  4ZTB A;  2PNS A;  2FTD A;  3WXE A;  1PVJ A;  4D8E A;  2HXZ A;  4MI7 A;  4XUI A;  1U9X A;  1EF7 A;  4CZW A;  3BY4 A;  1KHQ A;  4D8B A;  3BOW A;  2BTW A;  2ARY A;  3KFQ A;  3OVX A;  4W4U A;  3PRP A;  1F2B A;  4OVZ A;  1AYV A;  2Y6E A;  2PBH A;  1CB5 A;  3H6S A;  3LXS A;  1NB5 A;  3LFY A;  2AUZ A;  2HHN A;  1QMY A;  4I05 A;  3BPM A;  4CDF B;  4HWY A;  1DKI A;  1NLJ A;  1F29 A;  1STF E;  2HWK A;  1O0E A;  1A6R A;  1BGO A;  2YJ9 A;  1PCI A;  4KLB A;  2AVW A;  1IWD A;  3O1G A;  3CBJ A;  4X6H A;  2AGA A;  4PP1 A;  1SNK A;  4FIP A;  2FT2 A; 
#chains in the Genus database with same CATH homology
 3AI8 A;  1NB3 A;  1EWL A;  1CV8 A;  1GMY A;  3CH2 X;  1GLO A;  1Y08 A;  1CTE A;  2NQI A;  1ME3 A;  3PDF A;  4YVA A;  4AXM A;  2VHF A;  1NQC A;  3U8E A;  2XU3 A;  1YK8 A;  1MHW A;  4G54 A;  5PAD A;  5K16 A;  4BS5 A;  5EF4 A;  6PAD A;  4GUZ A;  3H8B A;  1CVZ A;  2E00 A;  3MHS A;  4YYS A;  3MHH A;  2BDL A;  3H8C A;  5CVN B;  2Y5B A;  2OP3 A;  2YJB A;  2R9O A;  1EWM A;  5JA7 A;  2R9N A;  1NL6 A;  1MS6 A;  2JQF R;  1F2A A;  2HD5 A;  2YJ8 A;  4NV7 A;  4Q8H A;  4BS6 A;  4W5B A;  1HUC B;  1AIM A;  2R9C A;  2FQ9 A;  4B55 A;  3BC3 A;  2B1N A;  2PAD A;  4I07 A;  1TL9 A;  3H89 A;  2JQG R;  3BCN A;  2DC8 A;  5CVO B;  1M6D A;  1VJV A;  3IV2 A;  1AU0 A;  1YK7 A;  1MEM A;  2DCA A;  3RVV A;  2NQG A;  1F2C A;  3KW9 A;  3IHP A;  3MTN A;  2ACT A;  2P0R A;  4RY2 A;  1CPJ A;  1AYW A;  1CSB B;  3ZUA A;  3OVZ A;  3KSE A;  2AIM A;  2CIO A;  4FJC A;  1AU3 A;  1K3B B;  1GEC E;  1SP4 B;  2DCB A;  1THE A;  1EWO A;  3F5V A;  4N79 A;  1NPZ A;  4YYQ A;  4XR7 A;  3HD3 A;  1E2T A;  4ZUX U;  3IMA A;  2VHS A;  4YV8 A;  3DF0 A;  4BQV A;  3V6E A;  1ZCM A;  2NQD B;  3K8U A;  4P6G A;  1PAD A;  1ITO A;  3C9E A;  1S4V A;  4DMX A;  3QJ3 A;  4NV8 A;  3N4C A;  2E02 A;  4BGF A;  3OF8 A;  7PCK A;  4N8W A;  1XKG A;  2BDZ A;  3O0U A;  1GCB A;  3P5W A;  2E03 A;  4CDC B;  2GFO A;  3PW3 A;  1DF0 A;  4YYR A;  2P7U A;  4WA6 A;  3HHI A;  1TU6 A;  1CS8 A;  2XU5 A;  3K9M A;  1PBH A;  1BY8 A;  1PPP A;  1MDW A;  4X6J A;  2DJG B;  2R6N A;  3D9W A;  1PE6 A;  1KFX L;  3MOR A;  4C5P A;  4PI3 A;  5A24 A;  2DC7 A;  2GHU A;  1U9W A;  1AU4 A;  1U9V A;  1CQD A;  3RVW A;  1W4T A;  2C0Y A;  1ICF A;  1TLO A;  3I3T A;  1VSN A;  1U9Q X;  4AXL A;  3PBH A;  4PAD A;  5CHV A;  1PXV A;  4MZO A;  3BPF A;  4X6I A;  4QH6 A;  2CB5 A;  2XU4 A;  4YYW A;  1X9Y A;  2FYE A;  1FH0 A;  4BPV A;  2DC9 A;  2OZ2 A;  4Q8G A;  3P5U A;  3PNR A;  2AU1 A;  2OUL A;  4QRV A;  4MSX A;  1W5R A;  2F7D A;  2VFC A;  1ATK A;  2R9F A;  3P5V A;  1KXR A;  1QDQ A;  4I04 A;  4QRG A;  1DEU A;  3P5X A;  1U5I A;  4P6E A;  5FPW A;  3LTW A;  4YYV A;  2AUX A;  3ERV A;  1POP A;  2DZY A;  1YAL A;  4CDD B;  3KKU A;  4W5C A;  2G6D A;  1ZIV A;  2YJC A;  2VFB A;  4CDE B;  3BWK A;  3RVX A;  2NQA A;  1PIP A;  4N4Z A;  1Q6K A;  2DCC A;  2E01 A;  5CHT A;  3WXG A;  2ATO A;  1JQP A;  3QSD A;  4OEM A;  8PCH A;  5J94 A;  2XU1 A;  3M99 A;  3K24 A;  2DJF B;  2PRE A;  1BQI A;  4PP2 E;  3KWZ A;  3QT4 A;  2FRA A;  1BP4 A;  5EGW A;  3S3Q A;  1PPN A;  2H7J A;  1MEG A;  4OEL A;  1QOL A;  2DZZ A;  2DCD A;  1KFU L;  4K7C A;  2AYN A;  1KHP A;  4MZS A;  2IBI A;  4YYU A;  3OIS A;  3N3K A;  2G8J A;  4QRX A;  3D6S A;  2HH5 A;  2R9M A;  1GX3 A;  3USV A;  1PPD A;  3TNX A;  2G8E A;  1AU2 A;  3KX1 A;  4FK5 A;  2FO5 A;  1YVB A;  2AYO A;  1AYU A;  3H7D A;  3IUT A;  1Y4H A;  1PPO A;  1QXP A;  4QBB A;  2O6X A;  3HWN A;  3N3G A;  1MIR A;  2B1M A;  3F75 A;  2F1G A;  2BSZ A;  3OF9 A;  3HHA A;  3S3R A;  5CVM A;  3I06 A;  2FRQ A;  2DC6 A;  3CH3 X;  3IEJ A;  2G7Y A;  5JH3 A;  1YT7 A;  2YJ2 A;  3WXF A;  9PAP A;  3CBK A;  1ME4 A;  3E1Z B;  2FUD A;  1CJL A;  3GCB A;  1EWP A;  3IOQ A;  3NHE A;  2AS8 A;  4DMY A;  2P86 A;  1AEC A;  4BSQ A;  3KWB X;  2IPP B;  2WBF X;  3B79 A;  5F02 A;  3V6C A;  2PNS A;  2FTD A;  3WXE A;  2HXZ A;  1W6F A;  4XUI A;  1U9X A;  1EF7 A;  4CZW A;  1KHQ A;  3BOW A;  2ARY A;  3KFQ A;  3OVX A;  4W4U A;  1F2B A;  1AYV A;  2Y6E A;  2PBH A;  1CB5 A;  3H6S A;  3LXS A;  1NB5 A;  3LFY A;  2AUZ A;  2HHN A;  1QMY A;  4I05 A;  3BPM A;  4CDF B;  4HWY A;  1NLJ A;  1F29 A;  1STF E;  1O0E A;  1A6R A;  1BGO A;  2YJ9 A;  1PCI A;  4KLB A;  2AVW A;  1IWD A;  3O1G A;  3CBJ A;  4X6H A;  4PP1 A;  1SNK A;  4FIP A;  2FT2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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