3KWBX

Structure of catk covalently bound to a dioxo-triazine inhibitor
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
215
structure length
215
Chain Sequence
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Dioxo-triazines as a novel series of cathepsin K inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 62
structure length 215
sequence length 215
chains with identical sequence Y
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2009-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3kwbX00
3I06A 3E1ZB 1QOLA 3KKUA 2XU5A 3F5VA 3O1GA 3RVXA 4I07A 3F75A 1EWMA 2YJ9A 1PIPA 3OVZA 1PPNA 4QBBA 1Y08A 2YJ2A 1PBHA 2BDZA 2DCAA 3KW9A 5F02A 3RVVA 1AU0A 3K24A 1BGOA 3U8EA 2HHNA 1F29A 4OELA 2GHUA 1AYWA 1U9QX 2JQGR 2E00A 1AECA 2AUZA 5K16A 4CDFB 2R9CA 3BCNA 1U9WA 2Y6EA 1S4VA 4W5CA 4MZSA 3N3KA 4X6IA 1AYVA 2P0RA 3CH3X 2C0YA 3K8UA 3QSDA 2ACTA 1QDQA 2OZ2A 2R9NA 4BPVA 1DF0A 2AUXA 1YVBA 8PCHA 5J94A 2O6XA 4KLBA 2DZYA 2HH5A 4I05A 2IPPB 5CHTA 2YJ8A 1GECE 3OVXA 1PPPA 1BY8A 2DC8A 3P5UA 2R9OA 1PADA 1YT7A 4WA6A 2ARYA 1PXVA 4DMYA 3CBKA 3D6SA 2XU4A 2FRQA 3BPFA 4I04A 1F2AA 1EWLA 4MZOA 1U9VA 1EF7A 3HHAA 4AXMA 4QRXA 5JH3A 3S3QA 2E02A 1VJVA 1BQIA 3QJ3A 1JQPA 2CB5A 3MHHA 4BS6A 1ATKA 1AIMA 1GLOA 1QXPA 3WXEA 7PCKA 1TL9A 2FT2A 3V6EA 2DJGB 1AU2A 4P6EA 4PI3A 4FJCA 1CB5A 1CQDA 2NQAA 5CVNB 3BOWA 4BS5A 3AI8A 3LFYA 2DC7A 3ZUAA 4QRGA 4BSQA 4XUIA 3HHIA 1GCBA 5PADA 4X6JA 3IUTA 1AYUA 3DF0A 3PW3A 1YK7A 1MHWA 3MTNA 2B1NA 3CBJA 3OISA 3QT4A 1X9YA 1NL6A 2AIMA 1M6DA 1PE6A 3H8BA 1THEA 1NPZA 2FQ9A 3H89A 1MEMA 4YYUA 1DEUA 3CH2X 4DMXA 4YYRA 2E01A 2AU1A 2NQDB 2FUDA 1HUCB 2AYNA 4AXLA 2FYEA 1CSBB 1CVZA 1GMYA 5CVMA 1CJLA 2F7DA 3H7DA 3HWNA 4HWYA 2ATOA 1SNKA 4XR7A 1A6RA 1MIRA 2G8EA 4X6HA 1F2BA 2GFOA 2R9FA 2YJCA 5FPWA 2BDLA 3GCBA 4K7CA 1ME3A 1EWOA 4CDEB 1YK8A 1NQCA 1CV8A 1KHQA 1ITOA 1STFE 3C9EA 4YYVA 2IBIA 3H8CA 2G6DA 4OEMA 3V6CA 2AVWA 2PNSA 2FO5A 4BQVA 3IHPA 3PBHA 3H6SA 3HD3A 2F1GA 3KWZA 2DCCA 2CIOA 3PNRA 1CS8A 4W5BA 3RVWA 5JA7A 4QH6A 2JQFR 4YV8A 3P5XA 1F2CA 1KHPA 2B1MA 2E03A 3IOQA 1TLOA 1POPA 2H7JA 4PADA 3M99A 3IEJA 3OF8A 2XU3A 4YYWA 3OF9A 3S3RA 4Q8HA 1NLJA 3IV2A 1BP4A 4CDDB 3BC3A 1TU6A 2HXZA 2PADA 2DZZA 1SP4B 1K3BB 3LXSA 2NQGA 2VHSA 3O0UA 3MHSA 1IWDA 2G7YA 1NB5A 2DCBA 3KWBX 1KFXL 2OP3A 1O0EA 1ZCMA 3PDFA 1ZIVA 4P6GA 3P5VA 4G54A 3N3GA 2FTDA 4N4ZA 6PADA 2R6NA 4RY2A 2DC6A 5CVOB 3WXGA 4YVAA 4FK5A 1YALA 1VSNA 2AYOA 3I3TA 1PCIA 3WXFA 1MS6A 4PP1A 2NQIA 1CTEA 4Q8GA 1PPDA 1MEGA 1QMYA 4W4UA 1PPOA 2G8JA 2XU1A 3USVA 3KSEA 5A24A 1Y4HA 3BWKA 4N8WA 3IMAA 4CZWA 3NHEA 2AS8A 2DJFB 2P86A 2FRAA 4YYQA 2R9MA 1KFUL 3K9MA 1AU4A 2DCDA 2HD5A 4YYSA 1U9XA 2PREA 1CPJA 1FH0A 1XKGA 4N79A 1AU3A 5EGWA 2Y5BA 1KXRA 1U5IA 9PAPA 3MORA 2DC9A 4MSXA 2VHFA 5EF4A 3TNXA 1MDWA 2PBHA 3ERVA 4ZUXU 4PP2E 4CDCB 1EWPA 3N4CA 1Q6KA 2OULA 3KX1A 3KFQA 1NB3A 3B79A 2WBFX 2YJBA 3P5WA 4FIPA 4QRVA 3BPMA 5CHVA 2P7UA 1ME4A 1ICFA
chains in the Genus database with same CATH superfamily
3I06A 3E1ZB 1QOLA 3KKUA 2XU5A 3F5VA 4XZXA 3O1GA 3RVXA 4I07A 3F75A 4BOSA 1EWMA 2YJ9A 1PIPA 3OVZA 2AGAA 1PPNA 4QBBA 1Y08A 2YJ2A 1PBHA 2BDZA 2DCAA 3KW9A 3O65A 5F02A 3RVVA 1AU0A 3K24A 1BGOA 3U8EA 2HHNA 1F29A 3PRPA 4OELA 2GHUA 1AYWA 1U9QX 2JQGR 2E00A 1AECA 2AUZA 5K16A 4CDFB 2R9CA 3BCNA 1U9WA 2Y6EA 1S4VA 4W5CA 4MZSA 3N3KA 4X6IA 1AYVA 2P0RA 5KO3A 3CH3X 2C0YA 3TMPA 3K8UA 3QSDA 2ACTA 4P16A 1QDQA 2OZ2A 2R9NA 4BPVA 1DF0A 2AUXA 1YVBA 3MTVA 3W30A 8PCHA 4D8BA 5J94A 2O6XA 4KLBA 2DZYA 2HH5A 4I05A 2IPPB 5CHTA 2YJ8A 1GECE 3OVXA 1PPPA 1BY8A 2DC8A 3P5UA 2R9OA 3PHXA 1PADA 1YT7A 4WA6A 2ARYA 4WURA 1PXVA 4DMYA 4MI7A 3CBKA 3D6SA 2XU4A 2FRQA 3BPFA 4I04A 2HWKA 3IFUA 4D8EA 1F2AA 1EWLA 4MZOA 1U9VA 1EF7A 3HHAA 4AXMA 4QRXA 5JH3A 3S3QA 2E02A 1VJVA 1BQIA 3QJ3A 1JQPA 2CB5A 3MHHA 4BS6A 1ATKA 1AIMA 1GLOA 1QXPA 3WXEA 7PCKA 1TL9A 2FT2A 3V6EA 2DJGB 1AU2A 4P6EA 4PI3A 4RF1A 4FJCA 1CB5A 1CQDA 2NQAA 5CVNB 3BOWA 4BS5A 3AI8A 3LFYA 5EZQA 2DC7A 3ZUAA 4QRGA 4BSQA 2JRIA 3PT2A 4XUIA 3HHIA 1GCBA 3B21A 5PADA 4X6JA 3IUTA 2BTWA 1AYUA 3DF0A 3PW3A 1YK7A 1MHWA 3MTNA 4HXDB 2B1NA 3CBJA 3OISA 3QT4A 3ZNHA 1X9YA 1NL6A 2AIMA 3OQCA 1M6DA 1PE6A 3H8BA 1THEA 2FE8A 1NPZA 2FQ9A 3H89A 4D8IA 1MEMA 4YYUA 4PT5A 1DEUA 3BB7A 3CH2X 4DMXA 2E01A 4YYRA 2AU1A 4R3DA 2NQDB 4ZTBA 2FUDA 1HUCB 2AYNA 4A5UA 4AXLA 2FYEA 1CSBB 1CVZA 1GMYA 5CVMA 1CJLA 2F7DA 3H7DA 3PRMA 3HWNA 4HWYA 3BY4A 4RKXA 2ATOA 1SNKA 4OVZA 4XR7A 1A6RA 1MIRA 2G8EA 4X6HA 1F2BA 2GFOA 3BBAA 1UKFA 2R9FA 2YJCA 5FPWA 2BU3A 2BDLA 3GCBA 4K7CA 1ME3A 4IP3A 1EWOA 4CDEB 3PHUA 1YK8A 1NQCA 1CV8A 1KHQA 1ITOA 1STFE 3C9EA 3W31A 4YYVA 2IBIA 3PSEA 3H8CA 2G6DA 4OEMA 3V6CA 2AVWA 2PNSA 2FO5A 4BQVA 3IHPA 3PBHA 3H6SA 3MJ5A 4OW0A 3HD3A 4MM3B 2F1GA 3KWZA 2DCCA 2CIOA 3PNRA 1CS8A 4W5BA 3RVWA 5JA7A 4QH6A 2JQFR 4YV8A 3P5XA 1F2CA 1KHPA 2B1MA 2E03A 3IOQA 1TLOA 2J7QC 1POPA 2H7JA 3TRKA 4PADA 3M99A 3IEJA 3OF8A 2XU3A 4YYWA 3OF9A 3S3RA 4Q8HA 1NLJA 3IV2A 1BP4A 4CDDB 3BC3A 1TU6A 2HXZA 2PADA 2DZZA 1SP4B 1K3BB 3LXSA 2NQGA 4IUMA 5JZEA 2VHSA 3O0UA 1PVJA 3MHSA 1IWDA 2G7YA 1NB5A 5EZSA 2DCBA 4RNAA 3KWBX 1KFXL 2DOSA 2OP3A 1O0EA 1ZCMA 3PDFA 1ZIVA 4P6GA 3P5VA 4RF0A 4GUAA 4G54A 3RNVA 2BTWB 3N3GA 2FTDA 4N4ZA 6PADA 2R6NA 4RY2A 2DC6A 5CVOB 3WXGA 4YVAA 4FK5A 1YALA 3PHWA 4BOUA 1VSNA 2AYOA 3I3TA 1PCIA 3WXFA 1MS6A 4PP1A 4REZA 2NQIA 1CTEA 4Q8GA 1PPDA 1MEGA 1QMYA 4W4UA 1PPOA 4BOPA 3MP2A 2G8JA 2XU1A 3USVA 3KSEA 5A24A 5E6JA 4OVZB 1Y4HA 2UZJA 3BWKA 4N8WA 1YZBA 3IMAA 4CZWA 3NHEA 1DKIA 2AS8A 2DJFB 2P86A 3C0RA 2FRAA 4YYQA 2R9MA 1KFUL 3K9MA 1AU4A 2DCDA 2HD5A 4YYSA 1U9XA 4M0WA 2PREA 2Z84A 1CPJA 4BOZA 1FH0A 1XKGA 4N79A 1AU3A 5EGWA 2Y5BA 1KXRA 1U5IA 9PAPA 2J7QA 3MORA 3E9SA 2DC9A 4MSXA 2VHFA 5EF4A 3TNXA 1MDWA 2PBHA 3ERVA 4BOQA 4ZUXU 4PP2E 4CDCB 1EWPA 2JTCA 3N4CA 1Q6KA 2OULA 3KX1A 3KFQA 1NB3A 3B79A 2WBFX 2YJBA 3P5WA 4FIPA 4QRVA 3BPMA 5CHVA 2P7UA 1ME4A 1ICFA
chains in the Genus database with same CATH topology
3I06A 3E1ZB 1QOLA 3KKUA 2XU5A 3F5VA 3O1GA 3RVXA 4I07A 3F75A 1EWMA 2YJ9A 1PIPA 3OVZA 1PPNA 4QBBA 1Y08A 2YJ2A 1PBHA 2BDZA 2DCAA 3KW9A 5F02A 3RVVA 1AU0A 3K24A 1BGOA 3U8EA 2HHNA 1F29A 4OELA 2GHUA 1AYWA 1U9QX 4GUZA 2JQGR 2E00A 1AECA 2AUZA 3LTWA 5K16A 4CDFB 2R9CA 3BCNA 1U9WA 3D9WA 2Y6EA 1S4VA 2VFCA 4MZSA 3N3KA 4W5CA 4X6IA 1AYVA 2P0RA 3CH3X 2C0YA 3K8UA 3QSDA 2ACTA 1QDQA 2OZ2A 2R9NA 4BPVA 1DF0A 2AUXA 1YVBA 8PCHA 5J94A 2O6XA 4KLBA 2DZYA 2HH5A 4I05A 2IPPB 5CHTA 2YJ8A 1GECE 3OVXA 1PPPA 1BY8A 2DC8A 3P5UA 2R9OA 1PADA 1GX3A 1YT7A 4WA6A 2ARYA 1PXVA 4DMYA 3CBKA 3D6SA 4NV8A 2XU4A 2FRQA 3BPFA 4I04A 1F2AA 1EWLA 4MZOA 1U9VA 1EF7A 3HHAA 4AXMA 4QRXA 5JH3A 3S3QA 2E02A 1VJVA 1BQIA 3QJ3A 1JQPA 2CB5A 3MHHA 2VFBA 4BS6A 1ATKA 1AIMA 1GLOA 1QXPA 3WXEA 7PCKA 1E2TA 1TL9A 2FT2A 3V6EA 2DJGB 1AU2A 4P6EA 4PI3A 4FJCA 1CB5A 1CQDA 2NQAA 5CVNB 3BOWA 4BS5A 3AI8A 3LFYA 2DC7A 3ZUAA 4QRGA 4BSQA 4XUIA 3HHIA 1W6FA 1GCBA 5PADA 4X6JA 3IUTA 1AYUA 3DF0A 3PW3A 1YK7A 4BGFA 1MHWA 3MTNA 2B1NA 3CBJA 3OISA 3QT4A 1X9YA 1NL6A 2AIMA 4B55A 1M6DA 1PE6A 3H8BA 1THEA 1NPZA 2FQ9A 3H89A 1MEMA 4YYUA 1DEUA 3CH2X 4DMXA 4YYRA 2E01A 2AU1A 2NQDB 2FUDA 1HUCB 2AYNA 4AXLA 2FYEA 1CSBB 1CVZA 1GMYA 5CVMA 1CJLA 2F7DA 3H7DA 3HWNA 4HWYA 2ATOA 1SNKA 4XR7A 1A6RA 1MIRA 2G8EA 4X6HA 1F2BA 2GFOA 2R9FA 2YJCA 5FPWA 2BDLA 3GCBA 4K7CA 1ME3A 1EWOA 4CDEB 1YK8A 1NQCA 1CV8A 1KHQA 1ITOA 1STFE 3C9EA 4YYVA 2IBIA 3H8CA 2G6DA 4OEMA 3V6CA 2AVWA 2PNSA 2FO5A 4BQVA 3IHPA 3PBHA 3H6SA 3HD3A 2F1GA 3KWZA 2DCCA 2CIOA 3PNRA 1CS8A 4W5BA 3RVWA 5JA7A 4QH6A 2JQFR 4YV8A 3P5XA 1F2CA 1KHPA 2B1MA 2E03A 3IOQA 1TLOA 1POPA 2H7JA 4PADA 3M99A 3IEJA 3OF8A 2XU3A 4YYWA 3OF9A 3S3RA 4Q8HA 1NLJA 3IV2A 1BP4A 4CDDB 3BC3A 1TU6A 2HXZA 2PADA 2DZZA 1SP4B 1K3BB 3LXSA 2NQGA 2VHSA 3O0UA 3MHSA 1IWDA 2G7YA 1NB5A 2DCBA 3KWBX 1KFXL 2OP3A 1O0EA 1ZCMA 3PDFA 1ZIVA 4P6GA 3P5VA 1W4TA 4G54A 3N3GA 2FTDA 4NV7A 4N4ZA 6PADA 2R6NA 4RY2A 2DC6A 5CVOB 3WXGA 4YVAA 4FK5A 1YALA 1VSNA 2AYOA 3I3TA 1PCIA 3WXFA 1MS6A 4PP1A 2NQIA 1CTEA 4Q8GA 1PPDA 1MEGA 1QMYA 4W4UA 1PPOA 2G8JA 2BSZA 2XU1A 3USVA 3KSEA 5A24A 1Y4HA 3BWKA 4N8WA 3IMAA 4CZWA 3NHEA 2AS8A 2DJFB 2P86A 2FRAA 4YYQA 2R9MA 1KFUL 3K9MA 1AU4A 2DCDA 2HD5A 4YYSA 1U9XA 1W5RA 2PREA 1CPJA 1FH0A 1XKGA 4N79A 1AU3A 5EGWA 2Y5BA 1KXRA 1U5IA 9PAPA 3MORA 2DC9A 4MSXA 2VHFA 5EF4A 3TNXA 1MDWA 4C5PA 2PBHA 3ERVA 4ZUXU 4PP2E 4CDCB 1EWPA 3N4CA 1Q6KA 2OULA 3KX1A 3KFQA 1NB3A 3B79A 2WBFX 2YJBA 3P5WA 4FIPA 4QRVA 3BPMA 5CHVA 2P7UA 1ME4A 1ICFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I06 A;  3E1Z B;  1QOL A;  3KKU A;  2XU5 A;  3F5V A;  3O1G A;  3RVX A;  4I07 A;  3F75 A;  1EWM A;  2YJ9 A;  1PIP A;  3OVZ A;  1PPN A;  4QBB A;  1Y08 A;  2YJ2 A;  1PBH A;  2BDZ A;  2DCA A;  3KW9 A;  5F02 A;  3RVV A;  1AU0 A;  3K24 A;  1BGO A;  3U8E A;  2HHN A;  1F29 A;  4OEL A;  2GHU A;  1AYW A;  1U9Q X;  2JQG R;  2E00 A;  1AEC A;  2AUZ A;  5K16 A;  4CDF B;  2R9C A;  3BCN A;  1U9W A;  2Y6E A;  1S4V A;  4W5C A;  4MZS A;  3N3K A;  4X6I A;  1AYV A;  2P0R A;  3CH3 X;  2C0Y A;  3K8U A;  3QSD A;  2ACT A;  1QDQ A;  2OZ2 A;  2R9N A;  4BPV A;  1DF0 A;  2AUX A;  1YVB A;  8PCH A;  5J94 A;  2O6X A;  4KLB A;  2DZY A;  2HH5 A;  4I05 A;  2IPP B;  5CHT A;  2YJ8 A;  1GEC E;  3OVX A;  1PPP A;  1BY8 A;  2DC8 A;  3P5U A;  2R9O A;  1PAD A;  1YT7 A;  4WA6 A;  2ARY A;  1PXV A;  4DMY A;  3CBK A;  3D6S A;  2XU4 A;  2FRQ A;  3BPF A;  4I04 A;  1F2A A;  1EWL A;  4MZO A;  1U9V A;  1EF7 A;  3HHA A;  4AXM A;  4QRX A;  5JH3 A;  3S3Q A;  2E02 A;  1VJV A;  1BQI A;  3QJ3 A;  1JQP A;  2CB5 A;  3MHH A;  4BS6 A;  1ATK A;  1AIM A;  1GLO A;  1QXP A;  3WXE A;  7PCK A;  1TL9 A;  2FT2 A;  3V6E A;  2DJG B;  1AU2 A;  4P6E A;  4PI3 A;  4FJC A;  1CB5 A;  1CQD A;  2NQA A;  5CVN B;  3BOW A;  4BS5 A;  3AI8 A;  3LFY A;  2DC7 A;  3ZUA A;  4QRG A;  4BSQ A;  4XUI A;  3HHI A;  1GCB A;  5PAD A;  4X6J A;  3IUT A;  1AYU A;  3DF0 A;  3PW3 A;  1YK7 A;  1MHW A;  3MTN A;  2B1N A;  3CBJ A;  3OIS A;  3QT4 A;  1X9Y A;  1NL6 A;  2AIM A;  1M6D A;  1PE6 A;  3H8B A;  1THE A;  1NPZ A;  2FQ9 A;  3H89 A;  1MEM A;  4YYU A;  1DEU A;  3CH2 X;  4DMX A;  4YYR A;  2E01 A;  2AU1 A;  2NQD B;  2FUD A;  1HUC B;  2AYN A;  4AXL A;  2FYE A;  1CSB B;  1CVZ A;  1GMY A;  5CVM A;  1CJL A;  2F7D A;  3H7D A;  3HWN A;  4HWY A;  2ATO A;  1SNK A;  4XR7 A;  1A6R A;  1MIR A;  2G8E A;  4X6H A;  1F2B A;  2GFO A;  2R9F A;  2YJC A;  5FPW A;  2BDL A;  3GCB A;  4K7C A;  1ME3 A;  1EWO A;  4CDE B;  1YK8 A;  1NQC A;  1CV8 A;  1KHQ A;  1ITO A;  1STF E;  3C9E A;  4YYV A;  2IBI A;  3H8C A;  2G6D A;  4OEM A;  3V6C A;  2AVW A;  2PNS A;  2FO5 A;  4BQV A;  3IHP A;  3PBH A;  3H6S A;  3HD3 A;  2F1G A;  3KWZ A;  2DCC A;  2CIO A;  3PNR A;  1CS8 A;  4W5B A;  3RVW A;  5JA7 A;  4QH6 A;  2JQF R;  4YV8 A;  3P5X A;  1F2C A;  1KHP A;  2B1M A;  2E03 A;  3IOQ A;  1TLO A;  1POP A;  2H7J A;  4PAD A;  3M99 A;  3IEJ A;  3OF8 A;  2XU3 A;  4YYW A;  3OF9 A;  3S3R A;  4Q8H A;  1NLJ A;  3IV2 A;  1BP4 A;  4CDD B;  3BC3 A;  1TU6 A;  2HXZ A;  2PAD A;  2DZZ A;  1SP4 B;  1K3B B;  3LXS A;  2NQG A;  2VHS A;  3O0U A;  3MHS A;  1IWD A;  2G7Y A;  1NB5 A;  2DCB A;  3KWB X;  1KFX L;  2OP3 A;  1O0E A;  1ZCM A;  3PDF A;  1ZIV A;  4P6G A;  3P5V A;  4G54 A;  3N3G A;  2FTD A;  4N4Z A;  6PAD A;  2R6N A;  4RY2 A;  2DC6 A;  5CVO B;  3WXG A;  4YVA A;  4FK5 A;  1YAL A;  1VSN A;  2AYO A;  3I3T A;  1PCI A;  3WXF A;  1MS6 A;  4PP1 A;  2NQI A;  1CTE A;  4Q8G A;  1PPD A;  1MEG A;  1QMY A;  4W4U A;  1PPO A;  2G8J A;  2XU1 A;  3USV A;  3KSE A;  5A24 A;  1Y4H A;  3BWK A;  4N8W A;  3IMA A;  4CZW A;  3NHE A;  2AS8 A;  2DJF B;  2P86 A;  2FRA A;  4YYQ A;  2R9M A;  1KFU L;  3K9M A;  1AU4 A;  2DCD A;  2HD5 A;  4YYS A;  1U9X A;  2PRE A;  1CPJ A;  1FH0 A;  1XKG A;  4N79 A;  1AU3 A;  5EGW A;  2Y5B A;  1KXR A;  1U5I A;  9PAP A;  3MOR A;  2DC9 A;  4MSX A;  2VHF A;  5EF4 A;  3TNX A;  1MDW A;  2PBH A;  3ERV A;  4ZUX U;  4PP2 E;  4CDC B;  1EWP A;  3N4C A;  1Q6K A;  2OUL A;  3KX1 A;  3KFQ A;  1NB3 A;  3B79 A;  2WBF X;  2YJB A;  3P5W A;  4FIP A;  4QRV A;  3BPM A;  5CHV A;  2P7U A;  1ME4 A;  1ICF A; 
#chains in the Genus database with same CATH topology
 3I06 A;  3E1Z B;  1QOL A;  3KKU A;  2XU5 A;  3F5V A;  4XZX A;  3O1G A;  3RVX A;  4I07 A;  3F75 A;  4BOS A;  1EWM A;  2YJ9 A;  1PIP A;  3OVZ A;  2AGA A;  1PPN A;  4QBB A;  1Y08 A;  2YJ2 A;  1PBH A;  2BDZ A;  2DCA A;  3KW9 A;  3O65 A;  5F02 A;  3RVV A;  1AU0 A;  3K24 A;  1BGO A;  3U8E A;  2HHN A;  1F29 A;  3PRP A;  4OEL A;  2GHU A;  1AYW A;  1U9Q X;  2JQG R;  2E00 A;  1AEC A;  2AUZ A;  5K16 A;  4CDF B;  2R9C A;  3BCN A;  1U9W A;  2Y6E A;  1S4V A;  4W5C A;  4MZS A;  3N3K A;  4X6I A;  1AYV A;  2P0R A;  5KO3 A;  3CH3 X;  2C0Y A;  3TMP A;  3K8U A;  3QSD A;  2ACT A;  4P16 A;  1QDQ A;  2OZ2 A;  2R9N A;  4BPV A;  1DF0 A;  2AUX A;  1YVB A;  3MTV A;  3W30 A;  8PCH A;  4D8B A;  5J94 A;  2O6X A;  4KLB A;  2DZY A;  2HH5 A;  4I05 A;  2IPP B;  5CHT A;  2YJ8 A;  1GEC E;  3OVX A;  1PPP A;  1BY8 A;  2DC8 A;  3P5U A;  2R9O A;  3PHX A;  1PAD A;  1YT7 A;  4WA6 A;  2ARY A;  4WUR A;  1PXV A;  4DMY A;  4MI7 A;  3CBK A;  3D6S A;  2XU4 A;  2FRQ A;  3BPF A;  4I04 A;  2HWK A;  3IFU A;  4D8E A;  1F2A A;  1EWL A;  4MZO A;  1U9V A;  1EF7 A;  3HHA A;  4AXM A;  4QRX A;  5JH3 A;  3S3Q A;  2E02 A;  1VJV A;  1BQI A;  3QJ3 A;  1JQP A;  2CB5 A;  3MHH A;  4BS6 A;  1ATK A;  1AIM A;  1GLO A;  1QXP A;  3WXE A;  7PCK A;  1TL9 A;  2FT2 A;  3V6E A;  2DJG B;  1AU2 A;  4P6E A;  4PI3 A;  4RF1 A;  4FJC A;  1CB5 A;  1CQD A;  2NQA A;  5CVN B;  3BOW A;  4BS5 A;  3AI8 A;  3LFY A;  5EZQ A;  2DC7 A;  3ZUA A;  4QRG A;  4BSQ A;  2JRI A;  3PT2 A;  4XUI A;  3HHI A;  1GCB A;  3B21 A;  5PAD A;  4X6J A;  3IUT A;  2BTW A;  1AYU A;  3DF0 A;  3PW3 A;  1YK7 A;  1MHW A;  3MTN A;  4HXD B;  2B1N A;  3CBJ A;  3OIS A;  3QT4 A;  3ZNH A;  1X9Y A;  1NL6 A;  2AIM A;  3OQC A;  1M6D A;  1PE6 A;  3H8B A;  1THE A;  2FE8 A;  1NPZ A;  2FQ9 A;  3H89 A;  4D8I A;  1MEM A;  4YYU A;  4PT5 A;  1DEU A;  3BB7 A;  3CH2 X;  4DMX A;  2E01 A;  4YYR A;  2AU1 A;  4R3D A;  2NQD B;  4ZTB A;  2FUD A;  1HUC B;  2AYN A;  4A5U A;  4AXL A;  2FYE A;  1CSB B;  1CVZ A;  1GMY A;  5CVM A;  1CJL A;  2F7D A;  3H7D A;  3PRM A;  3HWN A;  4HWY A;  3BY4 A;  4RKX A;  2ATO A;  1SNK A;  4OVZ A;  4XR7 A;  1A6R A;  1MIR A;  2G8E A;  4X6H A;  1F2B A;  2GFO A;  3BBA A;  1UKF A;  2R9F A;  2YJC A;  5FPW A;  2BU3 A;  2BDL A;  3GCB A;  4K7C A;  1ME3 A;  4IP3 A;  1EWO A;  4CDE B;  3PHU A;  1YK8 A;  1NQC A;  1CV8 A;  1KHQ A;  1ITO A;  1STF E;  3C9E A;  3W31 A;  4YYV A;  2IBI A;  3PSE A;  3H8C A;  2G6D A;  4OEM A;  3V6C A;  2AVW A;  2PNS A;  2FO5 A;  4BQV A;  3IHP A;  3PBH A;  3H6S A;  3MJ5 A;  4OW0 A;  3HD3 A;  4MM3 B;  2F1G A;  3KWZ A;  2DCC A;  2CIO A;  3PNR A;  1CS8 A;  4W5B A;  3RVW A;  5JA7 A;  4QH6 A;  2JQF R;  4YV8 A;  3P5X A;  1F2C A;  1KHP A;  2B1M A;  2E03 A;  3IOQ A;  1TLO A;  2J7Q C;  1POP A;  2H7J A;  3TRK A;  4PAD A;  3M99 A;  3IEJ A;  3OF8 A;  2XU3 A;  4YYW A;  3OF9 A;  3S3R A;  4Q8H A;  1NLJ A;  3IV2 A;  1BP4 A;  4CDD B;  3BC3 A;  1TU6 A;  2HXZ A;  2PAD A;  2DZZ A;  1SP4 B;  1K3B B;  3LXS A;  2NQG A;  4IUM A;  5JZE A;  2VHS A;  3O0U A;  1PVJ A;  3MHS A;  1IWD A;  2G7Y A;  1NB5 A;  5EZS A;  2DCB A;  4RNA A;  3KWB X;  1KFX L;  2DOS A;  2OP3 A;  1O0E A;  1ZCM A;  3PDF A;  1ZIV A;  4P6G A;  3P5V A;  4RF0 A;  4GUA A;  4G54 A;  3RNV A;  2BTW B;  3N3G A;  2FTD A;  4N4Z A;  6PAD A;  2R6N A;  4RY2 A;  2DC6 A;  5CVO B;  3WXG A;  4YVA A;  4FK5 A;  1YAL A;  3PHW A;  4BOU A;  1VSN A;  2AYO A;  3I3T A;  1PCI A;  3WXF A;  1MS6 A;  4PP1 A;  4REZ A;  2NQI A;  1CTE A;  4Q8G A;  1PPD A;  1MEG A;  1QMY A;  4W4U A;  1PPO A;  4BOP A;  3MP2 A;  2G8J A;  2XU1 A;  3USV A;  3KSE A;  5A24 A;  5E6J A;  4OVZ B;  1Y4H A;  2UZJ A;  3BWK A;  4N8W A;  1YZB A;  3IMA A;  4CZW A;  3NHE A;  1DKI A;  2AS8 A;  2DJF B;  2P86 A;  3C0R A;  2FRA A;  4YYQ A;  2R9M A;  1KFU L;  3K9M A;  1AU4 A;  2DCD A;  2HD5 A;  4YYS A;  1U9X A;  4M0W A;  2PRE A;  2Z84 A;  1CPJ A;  4BOZ A;  1FH0 A;  1XKG A;  4N79 A;  1AU3 A;  5EGW A;  2Y5B A;  1KXR A;  1U5I A;  9PAP A;  2J7Q A;  3MOR A;  3E9S A;  2DC9 A;  4MSX A;  2VHF A;  5EF4 A;  3TNX A;  1MDW A;  2PBH A;  3ERV A;  4BOQ A;  4ZUX U;  4PP2 E;  4CDC B;  1EWP A;  2JTC A;  3N4C A;  1Q6K A;  2OUL A;  3KX1 A;  3KFQ A;  1NB3 A;  3B79 A;  2WBF X;  2YJB A;  3P5W A;  4FIP A;  4QRV A;  3BPM A;  5CHV A;  2P7U A;  1ME4 A;  1ICF A; 
#chains in the Genus database with same CATH homology
 3I06 A;  3E1Z B;  1QOL A;  3KKU A;  2XU5 A;  3F5V A;  3O1G A;  3RVX A;  4I07 A;  3F75 A;  1EWM A;  2YJ9 A;  1PIP A;  3OVZ A;  1PPN A;  4QBB A;  1Y08 A;  2YJ2 A;  1PBH A;  2BDZ A;  2DCA A;  3KW9 A;  5F02 A;  3RVV A;  1AU0 A;  3K24 A;  1BGO A;  3U8E A;  2HHN A;  1F29 A;  4OEL A;  2GHU A;  1AYW A;  1U9Q X;  4GUZ A;  2JQG R;  2E00 A;  1AEC A;  2AUZ A;  3LTW A;  5K16 A;  4CDF B;  2R9C A;  3BCN A;  1U9W A;  3D9W A;  2Y6E A;  1S4V A;  2VFC A;  4MZS A;  3N3K A;  4W5C A;  4X6I A;  1AYV A;  2P0R A;  3CH3 X;  2C0Y A;  3K8U A;  3QSD A;  2ACT A;  1QDQ A;  2OZ2 A;  2R9N A;  4BPV A;  1DF0 A;  2AUX A;  1YVB A;  8PCH A;  5J94 A;  2O6X A;  4KLB A;  2DZY A;  2HH5 A;  4I05 A;  2IPP B;  5CHT A;  2YJ8 A;  1GEC E;  3OVX A;  1PPP A;  1BY8 A;  2DC8 A;  3P5U A;  2R9O A;  1PAD A;  1GX3 A;  1YT7 A;  4WA6 A;  2ARY A;  1PXV A;  4DMY A;  3CBK A;  3D6S A;  4NV8 A;  2XU4 A;  2FRQ A;  3BPF A;  4I04 A;  1F2A A;  1EWL A;  4MZO A;  1U9V A;  1EF7 A;  3HHA A;  4AXM A;  4QRX A;  5JH3 A;  3S3Q A;  2E02 A;  1VJV A;  1BQI A;  3QJ3 A;  1JQP A;  2CB5 A;  3MHH A;  2VFB A;  4BS6 A;  1ATK A;  1AIM A;  1GLO A;  1QXP A;  3WXE A;  7PCK A;  1E2T A;  1TL9 A;  2FT2 A;  3V6E A;  2DJG B;  1AU2 A;  4P6E A;  4PI3 A;  4FJC A;  1CB5 A;  1CQD A;  2NQA A;  5CVN B;  3BOW A;  4BS5 A;  3AI8 A;  3LFY A;  2DC7 A;  3ZUA A;  4QRG A;  4BSQ A;  4XUI A;  3HHI A;  1W6F A;  1GCB A;  5PAD A;  4X6J A;  3IUT A;  1AYU A;  3DF0 A;  3PW3 A;  1YK7 A;  4BGF A;  1MHW A;  3MTN A;  2B1N A;  3CBJ A;  3OIS A;  3QT4 A;  1X9Y A;  1NL6 A;  2AIM A;  4B55 A;  1M6D A;  1PE6 A;  3H8B A;  1THE A;  1NPZ A;  2FQ9 A;  3H89 A;  1MEM A;  4YYU A;  1DEU A;  3CH2 X;  4DMX A;  4YYR A;  2E01 A;  2AU1 A;  2NQD B;  2FUD A;  1HUC B;  2AYN A;  4AXL A;  2FYE A;  1CSB B;  1CVZ A;  1GMY A;  5CVM A;  1CJL A;  2F7D A;  3H7D A;  3HWN A;  4HWY A;  2ATO A;  1SNK A;  4XR7 A;  1A6R A;  1MIR A;  2G8E A;  4X6H A;  1F2B A;  2GFO A;  2R9F A;  2YJC A;  5FPW A;  2BDL A;  3GCB A;  4K7C A;  1ME3 A;  1EWO A;  4CDE B;  1YK8 A;  1NQC A;  1CV8 A;  1KHQ A;  1ITO A;  1STF E;  3C9E A;  4YYV A;  2IBI A;  3H8C A;  2G6D A;  4OEM A;  3V6C A;  2AVW A;  2PNS A;  2FO5 A;  4BQV A;  3IHP A;  3PBH A;  3H6S A;  3HD3 A;  2F1G A;  3KWZ A;  2DCC A;  2CIO A;  3PNR A;  1CS8 A;  4W5B A;  3RVW A;  5JA7 A;  4QH6 A;  2JQF R;  4YV8 A;  3P5X A;  1F2C A;  1KHP A;  2B1M A;  2E03 A;  3IOQ A;  1TLO A;  1POP A;  2H7J A;  4PAD A;  3M99 A;  3IEJ A;  3OF8 A;  2XU3 A;  4YYW A;  3OF9 A;  3S3R A;  4Q8H A;  1NLJ A;  3IV2 A;  1BP4 A;  4CDD B;  3BC3 A;  1TU6 A;  2HXZ A;  2PAD A;  2DZZ A;  1SP4 B;  1K3B B;  3LXS A;  2NQG A;  2VHS A;  3O0U A;  3MHS A;  1IWD A;  2G7Y A;  1NB5 A;  2DCB A;  3KWB X;  1KFX L;  2OP3 A;  1O0E A;  1ZCM A;  3PDF A;  1ZIV A;  4P6G A;  3P5V A;  1W4T A;  4G54 A;  3N3G A;  2FTD A;  4NV7 A;  4N4Z A;  6PAD A;  2R6N A;  4RY2 A;  2DC6 A;  5CVO B;  3WXG A;  4YVA A;  4FK5 A;  1YAL A;  1VSN A;  2AYO A;  3I3T A;  1PCI A;  3WXF A;  1MS6 A;  4PP1 A;  2NQI A;  1CTE A;  4Q8G A;  1PPD A;  1MEG A;  1QMY A;  4W4U A;  1PPO A;  2G8J A;  2BSZ A;  2XU1 A;  3USV A;  3KSE A;  5A24 A;  1Y4H A;  3BWK A;  4N8W A;  3IMA A;  4CZW A;  3NHE A;  2AS8 A;  2DJF B;  2P86 A;  2FRA A;  4YYQ A;  2R9M A;  1KFU L;  3K9M A;  1AU4 A;  2DCD A;  2HD5 A;  4YYS A;  1U9X A;  1W5R A;  2PRE A;  1CPJ A;  1FH0 A;  1XKG A;  4N79 A;  1AU3 A;  5EGW A;  2Y5B A;  1KXR A;  1U5I A;  9PAP A;  3MOR A;  2DC9 A;  4MSX A;  2VHF A;  5EF4 A;  3TNX A;  1MDW A;  4C5P A;  2PBH A;  3ERV A;  4ZUX U;  4PP2 E;  4CDC B;  1EWP A;  3N4C A;  1Q6K A;  2OUL A;  3KX1 A;  3KFQ A;  1NB3 A;  3B79 A;  2WBF X;  2YJB A;  3P5W A;  4FIP A;  4QRV A;  3BPM A;  5CHV A;  2P7U A;  1ME4 A;  1ICF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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