3TNXA

Structure of the precursor of a thermostable variant of papain at 2.6 angstroem resolution
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
310
structure length
310
Chain Sequence
NDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIRNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of a thermostable mutant of pro-papain reveals its activation mechanism
pubmed doi rcsb
molecule tags Hydrolase
source organism Carica papaya
molecule keywords Papain
total genus 106
structure length 310
sequence length 310
chains with identical sequence C
ec nomenclature ec 3.4.22.2: Papain.
pdb deposition date 2011-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3tnxA00
2BDLA 4YYUA 1AU4A 5J94A 2BDZA 1K3BB 2FRAA 2DZYA 4QRVA 3I3TA 3V6EA 1GLOA 3OVZA 2PBHA 1BP4A 2AS8A 1CVZA 1CJLA 1KHPA 3K24A 3S3RA 1U9WA 1AECA 1Y08A 2YJ8A 2AU1A 3F75A 2AUXA 4MZOA 3PNRA 2JQFR 3F5VA 3CH2X 2JQGR 4HWYA 4YYRA 1AU3A 4X6IA 2IPPB 2CIOA 3IUTA 3KKUA 2OP3A 2AUZA 2XU3A 1AU0A 1BQIA 3N4CA 5CHTA 1PADA 4XUIA 1JQPA 1Q6KA 5K16A 4QRGA 1CV8A 4QH6A 1YK7A 3RVVA 1QMYA 1A6RA 3P5VA 2E02A 3OF8A 1ZIVA 2YJ2A 2G8EA 3HD3A 2Y5BA 4AXLA 3LFYA 5EGWA 4N8WA 1AU2A 2DC7A 2YJBA 4CDEB 4P6EA 4BQVA 3LXSA 2YJCA 3E1ZB 1ME3A 2XU1A 3HWNA 4CDFB 3PDFA 2P86A 2C0YA 2R9CA 1DF0A 3IOQA 2FUDA 4I07A 1QOLA 5EF4A 2HH5A 2FO5A 3PBHA 4P6GA 3IEJA 4PI3A 1TL9A 4X6JA 2P0RA 2DCBA 3S3QA 2R6NA 1F2BA 4MSXA 5JH3A 2DC6A 3B79A 1PE6A 1YVBA 2R9NA 1YT7A 4RY2A 2G8JA 3P5UA 3BC3A 2YJ9A 2O6XA 4K7CA 2ARYA 3WXFA 4DMYA 2FT2A 4MZSA 3OISA 3O0UA 2DCDA 3NHEA 2AYNA 2AIMA 2DCCA 4X6HA 1BGOA 4DMXA 1PXVA 1PBHA 1THEA 3H8BA 3QT4A 4FK5A 1KXRA 2PNSA 4YVAA 4I04A 2F1GA 4CDCB 3O1GA 4N4ZA 5FPWA 2IBIA 1MIRA 3RVXA 1X9YA 3KFQA 3C9EA 1KFXL 1KHQA 3KX1A 1MDWA 2HXZA 2E01A 1F29A 3BCNA 3ZUAA 4W5CA 2R9MA 3MHSA 3DF0A 3N3KA 4Q8HA 4CZWA 1NLJA 1CB5A 1NB3A 3QJ3A 1PPDA 4ZUXU 3P5XA 1GMYA 3KWBX 3H7DA 1AYWA 1VJVA 5CVOB 4BSQA 1NL6A 1AYVA 4Q8GA 2FYEA 3M99A 3BOWA 1O0EA 3KW9A 1POPA 1CTEA 3PW3A 3BPFA 4FIPA 1YK8A 1FH0A 2G7YA 3MTNA 2HHNA 1GCBA 2PREA 3HHAA 4BS5A 2XU4A 3K8UA 4WA6A 2FTDA 4YYSA 2F7DA 3OF9A 3QSDA 3MHHA 1M6DA 4W5BA 5PADA 1QXPA 4AXMA 1TU6A 1EWOA 1KFUL 2VHSA 2E00A 1ICFA 3BPMA 2PADA 3AI8A 5CHVA 3P5WA 4YYWA 1NPZA 1BY8A 1EWPA 1F2CA 3CBKA 5F02A 3H6SA 2OZ2A 4N79A 1NB5A 2GFOA 1MS6A 2G6DA 8PCHA 3TNXA 1U9VA 1SNKA 3HHIA 4I05A 2VHFA 1U9QX 3USVA 3OVXA 1AYUA 4QBBA 2B1MA 1AIMA 1MHWA 3WXEA 3WXGA 2NQDB 2AVWA 3IHPA 3K9MA 1STFE 4FJCA 1PPPA 2B1NA 2Y6EA 2DCAA 2HD5A 3IMAA 3V6CA 2DJFB 1ATKA 5CVMA 2E03A 5CVNB 3IV2A 1EF7A 1U5IA 1IWDA 1PPNA 2WBFX 3MORA 2R9FA 1QDQA 1CSBB 1GECE 5JA7A 1EWMA 2CB5A 2R9OA 1Y4HA 1F2AA 1MEGA 2OULA 1CQDA 1EWLA 1ME4A 1S4VA 4XR7A 1U9XA 2H7JA 4BPVA 4W4UA 3H8CA 3ERVA 3KWZA 3KSEA 4YYVA 3BWKA 1VSNA 1PCIA 1YALA 2NQAA 1PIPA 2XU5A 2P7UA 4OEMA 6PADA 1PPOA 1SP4B 4YV8A 5A24A 3CBJA 1NQCA 3RVWA 4BS6A 2DC8A 2NQGA 1HUCB 2NQIA 4KLBA 1XKGA 2DC9A 3N3GA 9PAPA 1CPJA 3GCBA 4QRXA 4PP1A 1TLOA 1ZCMA 2FRQA 2DJGB 3I06A 4G54A 4CDDB 2GHUA 3H89A 2ACTA 2DZZA 1CS8A 4YYQA 4PADA 4PP2E 1ITOA 7PCKA 2FQ9A 3U8EA 3D6SA 1DEUA 1MEMA 4OELA 2AYOA 2ATOA 3CH3X
chains in the Genus database with same CATH superfamily
2BDLA 4YYUA 1AU4A 5J94A 2BDZA 3PHWA 1K3BB 2FRAA 2DZYA 4QRVA 3I3TA 3V6EA 1GLOA 3OVZA 4RF1A 2PBHA 1BP4A 2AS8A 1CVZA 1CJLA 1KHPA 3K24A 3S3RA 3PHXA 1U9WA 3BY4A 1AECA 1Y08A 2YJ8A 2AU1A 3F75A 2AUXA 3B21A 4MZOA 3PNRA 2JQFR 3F5VA 3CH2X 2JQGR 4HWYA 3PRMA 4YYRA 1AU3A 2BTWA 4X6IA 2IPPB 2CIOA 3IUTA 3KKUA 2OP3A 2AUZA 2XU3A 1AU0A 1BQIA 3N4CA 5CHTA 1PADA 4XUIA 4D8EA 1JQPA 1Q6KA 5K16A 4BOPA 4QRGA 1CV8A 4OVZA 4QH6A 2Z84A 1YK7A 3RVVA 4BOUA 1PVJA 2JRIA 1QMYA 1A6RA 4PT5A 3P5VA 2E02A 3OF8A 4RKXA 3ZNHA 3MJ5A 2HWKA 1ZIVA 2YJ2A 2G8EA 3HD3A 2Y5BA 4AXLA 3LFYA 5EGWA 4N8WA 1AU2A 2DC7A 4BOSA 2YJBA 4CDEB 4D8BA 4P6EA 4BQVA 3LXSA 4GUAA 2YJCA 3E1ZB 1ME3A 2XU1A 3HWNA 4OVZB 4CDFB 3PDFA 3PT2A 2P86A 2C0YA 2R9CA 1DF0A 3IOQA 2FUDA 4I07A 1QOLA 5EF4A 2HH5A 2FO5A 3PBHA 4P6GA 3IEJA 4PI3A 2JTCA 1TL9A 1UKFA 2P0RA 4X6JA 3E9SA 3PRPA 2DCBA 3S3QA 2DOSA 2R6NA 1F2BA 4MSXA 5JH3A 2DC6A 3B79A 1PE6A 1YVBA 2R9NA 1YT7A 4RY2A 2G8JA 1YZBA 3P5UA 3BC3A 2YJ9A 2O6XA 4K7CA 2ARYA 3WXFA 4DMYA 2FT2A 4MZSA 3OISA 3O0UA 2DCDA 3NHEA 2AYNA 2AIMA 2DCCA 4X6HA 1BGOA 4DMXA 1PXVA 1PBHA 1THEA 3H8BA 3QT4A 4FK5A 1KXRA 2PNSA 4YVAA 4I04A 2F1GA 5JZEA 4CDCB 3O1GA 4N4ZA 5FPWA 2IBIA 1MIRA 2AGAA 3RVXA 1X9YA 3KFQA 3C9EA 1KFXL 1KHQA 3KX1A 1MDWA 2HXZA 5EZSA 1DKIA 2E01A 1F29A 3BCNA 3ZUAA 4W5CA 2R9MA 3MHSA 3DF0A 3N3KA 4Q8HA 4CZWA 1NLJA 4MM3B 1CB5A 1NB3A 3QJ3A 5EZQA 1PPDA 4ZUXU 3P5XA 1GMYA 3KWBX 3TRKA 3H7DA 1AYWA 4IUMA 2J7QC 1VJVA 5CVOB 4BSQA 1NL6A 1AYVA 2J7QA 2FYEA 4Q8GA 2BTWB 3M99A 3BOWA 1O0EA 3KW9A 1POPA 1CTEA 3PW3A 3BPFA 4FIPA 1YK8A 1FH0A 2G7YA 3MTNA 2HHNA 1GCBA 2PREA 3HHAA 4BS5A 2XU4A 3K8UA 3PSEA 4WA6A 2FTDA 4XZXA 4YYSA 4ZTBA 2F7DA 4A5UA 3OF9A 3QSDA 3MHHA 1M6DA 4W5BA 5PADA 3O65A 1QXPA 4AXMA 1TU6A 1EWOA 1KFUL 2VHSA 2E00A 4OW0A 1ICFA 3BPMA 2PADA 3AI8A 5CHVA 2FE8A 4WURA 3P5WA 4YYWA 1NPZA 1BY8A 1EWPA 1F2CA 3CBKA 5F02A 3H6SA 2OZ2A 4N79A 1NB5A 2GFOA 1MS6A 2G6DA 8PCHA 4M0WA 3TNXA 1U9VA 1SNKA 3HHIA 4I05A 2VHFA 1U9QX 3USVA 3OVXA 1AYUA 4QBBA 2B1MA 1AIMA 1MHWA 4RF0A 3WXEA 3WXGA 4RNAA 2NQDB 2AVWA 5E6JA 3IHPA 3K9MA 3TMPA 1STFE 4FJCA 1PPPA 2B1NA 2Y6EA 2DCAA 2HD5A 3IMAA 3V6CA 2DJFB 1ATKA 5CVMA 2E03A 5CVNB 3IV2A 1EF7A 3PHUA 3OQCA 1U5IA 1IWDA 1PPNA 2WBFX 3MORA 4HXDB 2R9FA 1QDQA 2UZJA 1CSBB 1GECE 5JA7A 5KO3A 1EWMA 4D8IA 2CB5A 2R9OA 1Y4HA 4R3DA 1F2AA 1MEGA 2OULA 3MP2A 1CQDA 1EWLA 1ME4A 1S4VA 3IFUA 4XR7A 1U9XA 2H7JA 4BPVA 4W4UA 3H8CA 3ERVA 3KWZA 3KSEA 4YYVA 3BWKA 1VSNA 1PCIA 3RNVA 1YALA 2NQAA 3BB7A 1PIPA 2XU5A 2P7UA 3BBAA 4IP3A 4OEMA 6PADA 1PPOA 1SP4B 4YV8A 5A24A 3CBJA 3W31A 1NQCA 3RVWA 4BS6A 2DC8A 2NQGA 4BOQA 1HUCB 2NQIA 4KLBA 1XKGA 4MI7A 2DC9A 3N3GA 9PAPA 1CPJA 3GCBA 3W30A 4QRXA 4PP1A 1TLOA 1ZCMA 2FRQA 2DJGB 3I06A 4G54A 4CDDB 2GHUA 3H89A 2ACTA 2DZZA 1CS8A 4YYQA 4REZA 2BU3A 3C0RA 4PADA 4PP2E 3MTVA 1ITOA 4BOZA 2FQ9A 7PCKA 4P16A 3U8EA 3D6SA 1DEUA 1MEMA 4OELA 2AYOA 2ATOA 3CH3X
chains in the Genus database with same CATH topology
2BDLA 4YYUA 1AU4A 5J94A 2BDZA 1K3BB 2FRAA 4C5PA 2DZYA 4QRVA 3I3TA 3V6EA 1GLOA 3OVZA 2PBHA 1BP4A 2AS8A 1CVZA 1CJLA 1KHPA 3K24A 3S3RA 1U9WA 1AECA 1Y08A 2YJ8A 2AU1A 3F75A 2AUXA 4MZOA 1GX3A 3PNRA 2JQFR 3F5VA 3CH2X 2JQGR 4HWYA 4YYRA 1AU3A 4X6IA 2IPPB 2CIOA 3IUTA 3KKUA 2OP3A 2AUZA 2XU3A 1AU0A 1BQIA 3N4CA 5CHTA 1PADA 4XUIA 1JQPA 1Q6KA 5K16A 4QRGA 1CV8A 4QH6A 1YK7A 3RVVA 1QMYA 1A6RA 3P5VA 4GUZA 2E02A 3OF8A 1ZIVA 2YJ2A 2G8EA 3HD3A 2Y5BA 4AXLA 3LFYA 5EGWA 4N8WA 1AU2A 2DC7A 2YJBA 4CDEB 4P6EA 4B55A 4BQVA 3LXSA 2YJCA 3E1ZB 1ME3A 2XU1A 3HWNA 4CDFB 3PDFA 2P86A 2C0YA 2R9CA 1DF0A 3IOQA 2FUDA 4I07A 1QOLA 5EF4A 2HH5A 2FO5A 3PBHA 4NV7A 4P6GA 3IEJA 4PI3A 1TL9A 4X6JA 2P0RA 2DCBA 3S3QA 2R6NA 1F2BA 4MSXA 5JH3A 2DC6A 3B79A 1PE6A 1YVBA 2R9NA 1YT7A 4RY2A 2G8JA 3P5UA 3BC3A 2YJ9A 2O6XA 4K7CA 2ARYA 3WXFA 4DMYA 2FT2A 4MZSA 3OISA 3O0UA 2DCDA 3NHEA 2AYNA 2AIMA 2DCCA 4X6HA 1BGOA 4DMXA 1PXVA 1PBHA 1THEA 3H8BA 3QT4A 4FK5A 1KXRA 2PNSA 4YVAA 4I04A 2F1GA 4CDCB 3O1GA 4N4ZA 5FPWA 2IBIA 1MIRA 3D9WA 3RVXA 1X9YA 3KFQA 3C9EA 1KFXL 1KHQA 3KX1A 1MDWA 1W4TA 2HXZA 2E01A 1F29A 3BCNA 3ZUAA 4NV8A 4W5CA 2R9MA 3MHSA 3DF0A 3N3KA 4Q8HA 4CZWA 1NLJA 1CB5A 1NB3A 3QJ3A 1PPDA 4ZUXU 3P5XA 1GMYA 2BSZA 3KWBX 3H7DA 1AYWA 4BGFA 1VJVA 5CVOB 4BSQA 1NL6A 1AYVA 4Q8GA 2FYEA 3M99A 3BOWA 1O0EA 3KW9A 1POPA 1CTEA 3PW3A 3BPFA 4FIPA 1YK8A 1FH0A 2G7YA 3MTNA 2HHNA 1GCBA 2PREA 3HHAA 4BS5A 2XU4A 3K8UA 4WA6A 2FTDA 4YYSA 2F7DA 3OF9A 3QSDA 3MHHA 1M6DA 4W5BA 5PADA 1QXPA 4AXMA 1TU6A 1EWOA 1KFUL 2VHSA 2E00A 1ICFA 3BPMA 2PADA 3AI8A 5CHVA 3P5WA 4YYWA 1NPZA 1BY8A 1EWPA 1F2CA 3CBKA 5F02A 3H6SA 2OZ2A 4N79A 1NB5A 2GFOA 1MS6A 2G6DA 8PCHA 3TNXA 1U9VA 1SNKA 3HHIA 4I05A 2VHFA 1U9QX 3USVA 3OVXA 1AYUA 1W6FA 2B1MA 4QBBA 1AIMA 1MHWA 3WXEA 3WXGA 2NQDB 2AVWA 3IHPA 3K9MA 1STFE 4FJCA 1PPPA 2B1NA 2Y6EA 2DCAA 2HD5A 3IMAA 3V6CA 2DJFB 1ATKA 5CVMA 2E03A 5CVNB 3IV2A 1EF7A 1U5IA 1IWDA 1PPNA 2WBFX 3MORA 2R9FA 1QDQA 1E2TA 3LTWA 1CSBB 1GECE 5JA7A 2VFBA 1EWMA 2CB5A 2R9OA 1W5RA 1Y4HA 1F2AA 1MEGA 2OULA 1CQDA 1EWLA 1ME4A 1S4VA 4XR7A 1U9XA 2H7JA 4BPVA 4W4UA 3H8CA 3ERVA 3KWZA 3KSEA 4YYVA 3BWKA 1VSNA 1PCIA 1YALA 2NQAA 1PIPA 2XU5A 2P7UA 4OEMA 6PADA 1PPOA 1SP4B 4YV8A 5A24A 3CBJA 1NQCA 3RVWA 4BS6A 2DC8A 2NQGA 1HUCB 2NQIA 4KLBA 1XKGA 2DC9A 3N3GA 9PAPA 1CPJA 3GCBA 4QRXA 4PP1A 1TLOA 1ZCMA 2FRQA 2DJGB 3I06A 4G54A 4CDDB 2GHUA 3H89A 2ACTA 2DZZA 1CS8A 4YYQA 4PADA 4PP2E 1ITOA 7PCKA 2FQ9A 2VFCA 3U8EA 3D6SA 1DEUA 1MEMA 4OELA 2AYOA 2ATOA 3CH3X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BDL A;  4YYU A;  1AU4 A;  5J94 A;  2BDZ A;  1K3B B;  2FRA A;  2DZY A;  4QRV A;  3I3T A;  3V6E A;  1GLO A;  3OVZ A;  2PBH A;  1BP4 A;  2AS8 A;  1CVZ A;  1CJL A;  1KHP A;  3K24 A;  3S3R A;  1U9W A;  1AEC A;  1Y08 A;  2YJ8 A;  2AU1 A;  3F75 A;  2AUX A;  4MZO A;  3PNR A;  2JQF R;  3F5V A;  3CH2 X;  2JQG R;  4HWY A;  4YYR A;  1AU3 A;  4X6I A;  2IPP B;  2CIO A;  3IUT A;  3KKU A;  2OP3 A;  2AUZ A;  2XU3 A;  1AU0 A;  1BQI A;  3N4C A;  5CHT A;  1PAD A;  4XUI A;  1JQP A;  1Q6K A;  5K16 A;  4QRG A;  1CV8 A;  4QH6 A;  1YK7 A;  3RVV A;  1QMY A;  1A6R A;  3P5V A;  2E02 A;  3OF8 A;  1ZIV A;  2YJ2 A;  2G8E A;  3HD3 A;  2Y5B A;  4AXL A;  3LFY A;  5EGW A;  4N8W A;  1AU2 A;  2DC7 A;  2YJB A;  4CDE B;  4P6E A;  4BQV A;  3LXS A;  2YJC A;  3E1Z B;  1ME3 A;  2XU1 A;  3HWN A;  4CDF B;  3PDF A;  2P86 A;  2C0Y A;  2R9C A;  1DF0 A;  3IOQ A;  2FUD A;  4I07 A;  1QOL A;  5EF4 A;  2HH5 A;  2FO5 A;  3PBH A;  4P6G A;  3IEJ A;  4PI3 A;  1TL9 A;  4X6J A;  2P0R A;  2DCB A;  3S3Q A;  2R6N A;  1F2B A;  4MSX A;  5JH3 A;  2DC6 A;  3B79 A;  1PE6 A;  1YVB A;  2R9N A;  1YT7 A;  4RY2 A;  2G8J A;  3P5U A;  3BC3 A;  2YJ9 A;  2O6X A;  4K7C A;  2ARY A;  3WXF A;  4DMY A;  2FT2 A;  4MZS A;  3OIS A;  3O0U A;  2DCD A;  3NHE A;  2AYN A;  2AIM A;  2DCC A;  4X6H A;  1BGO A;  4DMX A;  1PXV A;  1PBH A;  1THE A;  3H8B A;  3QT4 A;  4FK5 A;  1KXR A;  2PNS A;  4YVA A;  4I04 A;  2F1G A;  4CDC B;  3O1G A;  4N4Z A;  5FPW A;  2IBI A;  1MIR A;  3RVX A;  1X9Y A;  3KFQ A;  3C9E A;  1KFX L;  1KHQ A;  3KX1 A;  1MDW A;  2HXZ A;  2E01 A;  1F29 A;  3BCN A;  3ZUA A;  4W5C A;  2R9M A;  3MHS A;  3DF0 A;  3N3K A;  4Q8H A;  4CZW A;  1NLJ A;  1CB5 A;  1NB3 A;  3QJ3 A;  1PPD A;  4ZUX U;  3P5X A;  1GMY A;  3KWB X;  3H7D A;  1AYW A;  1VJV A;  5CVO B;  4BSQ A;  1NL6 A;  1AYV A;  4Q8G A;  2FYE A;  3M99 A;  3BOW A;  1O0E A;  3KW9 A;  1POP A;  1CTE A;  3PW3 A;  3BPF A;  4FIP A;  1YK8 A;  1FH0 A;  2G7Y A;  3MTN A;  2HHN A;  1GCB A;  2PRE A;  3HHA A;  4BS5 A;  2XU4 A;  3K8U A;  4WA6 A;  2FTD A;  4YYS A;  2F7D A;  3OF9 A;  3QSD A;  3MHH A;  1M6D A;  4W5B A;  5PAD A;  1QXP A;  4AXM A;  1TU6 A;  1EWO A;  1KFU L;  2VHS A;  2E00 A;  1ICF A;  3BPM A;  2PAD A;  3AI8 A;  5CHV A;  3P5W A;  4YYW A;  1NPZ A;  1BY8 A;  1EWP A;  1F2C A;  3CBK A;  5F02 A;  3H6S A;  2OZ2 A;  4N79 A;  1NB5 A;  2GFO A;  1MS6 A;  2G6D A;  8PCH A;  3TNX A;  1U9V A;  1SNK A;  3HHI A;  4I05 A;  2VHF A;  1U9Q X;  3USV A;  3OVX A;  1AYU A;  4QBB A;  2B1M A;  1AIM A;  1MHW A;  3WXE A;  3WXG A;  2NQD B;  2AVW A;  3IHP A;  3K9M A;  1STF E;  4FJC A;  1PPP A;  2B1N A;  2Y6E A;  2DCA A;  2HD5 A;  3IMA A;  3V6C A;  2DJF B;  1ATK A;  5CVM A;  2E03 A;  5CVN B;  3IV2 A;  1EF7 A;  1U5I A;  1IWD A;  1PPN A;  2WBF X;  3MOR A;  2R9F A;  1QDQ A;  1CSB B;  1GEC E;  5JA7 A;  1EWM A;  2CB5 A;  2R9O A;  1Y4H A;  1F2A A;  1MEG A;  2OUL A;  1CQD A;  1EWL A;  1ME4 A;  1S4V A;  4XR7 A;  1U9X A;  2H7J A;  4BPV A;  4W4U A;  3H8C A;  3ERV A;  3KWZ A;  3KSE A;  4YYV A;  3BWK A;  1VSN A;  1PCI A;  1YAL A;  2NQA A;  1PIP A;  2XU5 A;  2P7U A;  4OEM A;  6PAD A;  1PPO A;  1SP4 B;  4YV8 A;  5A24 A;  3CBJ A;  1NQC A;  3RVW A;  4BS6 A;  2DC8 A;  2NQG A;  1HUC B;  2NQI A;  4KLB A;  1XKG A;  2DC9 A;  3N3G A;  9PAP A;  1CPJ A;  3GCB A;  4QRX A;  4PP1 A;  1TLO A;  1ZCM A;  2FRQ A;  2DJG B;  3I06 A;  4G54 A;  4CDD B;  2GHU A;  3H89 A;  2ACT A;  2DZZ A;  1CS8 A;  4YYQ A;  4PAD A;  4PP2 E;  1ITO A;  7PCK A;  2FQ9 A;  3U8E A;  3D6S A;  1DEU A;  1MEM A;  4OEL A;  2AYO A;  2ATO A;  3CH3 X; 
#chains in the Genus database with same CATH topology
 2BDL A;  4YYU A;  1AU4 A;  5J94 A;  2BDZ A;  3PHW A;  1K3B B;  2FRA A;  2DZY A;  4QRV A;  3I3T A;  3V6E A;  1GLO A;  3OVZ A;  4RF1 A;  2PBH A;  1BP4 A;  2AS8 A;  1CVZ A;  1CJL A;  1KHP A;  3K24 A;  3S3R A;  3PHX A;  1U9W A;  3BY4 A;  1AEC A;  1Y08 A;  2YJ8 A;  2AU1 A;  3F75 A;  2AUX A;  3B21 A;  4MZO A;  3PNR A;  2JQF R;  3F5V A;  3CH2 X;  2JQG R;  4HWY A;  3PRM A;  4YYR A;  1AU3 A;  2BTW A;  4X6I A;  2IPP B;  2CIO A;  3IUT A;  3KKU A;  2OP3 A;  2AUZ A;  2XU3 A;  1AU0 A;  1BQI A;  3N4C A;  5CHT A;  1PAD A;  4XUI A;  4D8E A;  1JQP A;  1Q6K A;  5K16 A;  4BOP A;  4QRG A;  1CV8 A;  4OVZ A;  4QH6 A;  2Z84 A;  1YK7 A;  3RVV A;  4BOU A;  1PVJ A;  2JRI A;  1QMY A;  1A6R A;  4PT5 A;  3P5V A;  2E02 A;  3OF8 A;  4RKX A;  3ZNH A;  3MJ5 A;  2HWK A;  1ZIV A;  2YJ2 A;  2G8E A;  3HD3 A;  2Y5B A;  4AXL A;  3LFY A;  5EGW A;  4N8W A;  1AU2 A;  2DC7 A;  4BOS A;  2YJB A;  4CDE B;  4D8B A;  4P6E A;  4BQV A;  3LXS A;  4GUA A;  2YJC A;  3E1Z B;  1ME3 A;  2XU1 A;  3HWN A;  4OVZ B;  4CDF B;  3PDF A;  3PT2 A;  2P86 A;  2C0Y A;  2R9C A;  1DF0 A;  3IOQ A;  2FUD A;  4I07 A;  1QOL A;  5EF4 A;  2HH5 A;  2FO5 A;  3PBH A;  4P6G A;  3IEJ A;  4PI3 A;  2JTC A;  1TL9 A;  1UKF A;  2P0R A;  4X6J A;  3E9S A;  3PRP A;  2DCB A;  3S3Q A;  2DOS A;  2R6N A;  1F2B A;  4MSX A;  5JH3 A;  2DC6 A;  3B79 A;  1PE6 A;  1YVB A;  2R9N A;  1YT7 A;  4RY2 A;  2G8J A;  1YZB A;  3P5U A;  3BC3 A;  2YJ9 A;  2O6X A;  4K7C A;  2ARY A;  3WXF A;  4DMY A;  2FT2 A;  4MZS A;  3OIS A;  3O0U A;  2DCD A;  3NHE A;  2AYN A;  2AIM A;  2DCC A;  4X6H A;  1BGO A;  4DMX A;  1PXV A;  1PBH A;  1THE A;  3H8B A;  3QT4 A;  4FK5 A;  1KXR A;  2PNS A;  4YVA A;  4I04 A;  2F1G A;  5JZE A;  4CDC B;  3O1G A;  4N4Z A;  5FPW A;  2IBI A;  1MIR A;  2AGA A;  3RVX A;  1X9Y A;  3KFQ A;  3C9E A;  1KFX L;  1KHQ A;  3KX1 A;  1MDW A;  2HXZ A;  5EZS A;  1DKI A;  2E01 A;  1F29 A;  3BCN A;  3ZUA A;  4W5C A;  2R9M A;  3MHS A;  3DF0 A;  3N3K A;  4Q8H A;  4CZW A;  1NLJ A;  4MM3 B;  1CB5 A;  1NB3 A;  3QJ3 A;  5EZQ A;  1PPD A;  4ZUX U;  3P5X A;  1GMY A;  3KWB X;  3TRK A;  3H7D A;  1AYW A;  4IUM A;  2J7Q C;  1VJV A;  5CVO B;  4BSQ A;  1NL6 A;  1AYV A;  2J7Q A;  2FYE A;  4Q8G A;  2BTW B;  3M99 A;  3BOW A;  1O0E A;  3KW9 A;  1POP A;  1CTE A;  3PW3 A;  3BPF A;  4FIP A;  1YK8 A;  1FH0 A;  2G7Y A;  3MTN A;  2HHN A;  1GCB A;  2PRE A;  3HHA A;  4BS5 A;  2XU4 A;  3K8U A;  3PSE A;  4WA6 A;  2FTD A;  4XZX A;  4YYS A;  4ZTB A;  2F7D A;  4A5U A;  3OF9 A;  3QSD A;  3MHH A;  1M6D A;  4W5B A;  5PAD A;  3O65 A;  1QXP A;  4AXM A;  1TU6 A;  1EWO A;  1KFU L;  2VHS A;  2E00 A;  4OW0 A;  1ICF A;  3BPM A;  2PAD A;  3AI8 A;  5CHV A;  2FE8 A;  4WUR A;  3P5W A;  4YYW A;  1NPZ A;  1BY8 A;  1EWP A;  1F2C A;  3CBK A;  5F02 A;  3H6S A;  2OZ2 A;  4N79 A;  1NB5 A;  2GFO A;  1MS6 A;  2G6D A;  8PCH A;  4M0W A;  3TNX A;  1U9V A;  1SNK A;  3HHI A;  4I05 A;  2VHF A;  1U9Q X;  3USV A;  3OVX A;  1AYU A;  4QBB A;  2B1M A;  1AIM A;  1MHW A;  4RF0 A;  3WXE A;  3WXG A;  4RNA A;  2NQD B;  2AVW A;  5E6J A;  3IHP A;  3K9M A;  3TMP A;  1STF E;  4FJC A;  1PPP A;  2B1N A;  2Y6E A;  2DCA A;  2HD5 A;  3IMA A;  3V6C A;  2DJF B;  1ATK A;  5CVM A;  2E03 A;  5CVN B;  3IV2 A;  1EF7 A;  3PHU A;  3OQC A;  1U5I A;  1IWD A;  1PPN A;  2WBF X;  3MOR A;  4HXD B;  2R9F A;  1QDQ A;  2UZJ A;  1CSB B;  1GEC E;  5JA7 A;  5KO3 A;  1EWM A;  4D8I A;  2CB5 A;  2R9O A;  1Y4H A;  4R3D A;  1F2A A;  1MEG A;  2OUL A;  3MP2 A;  1CQD A;  1EWL A;  1ME4 A;  1S4V A;  3IFU A;  4XR7 A;  1U9X A;  2H7J A;  4BPV A;  4W4U A;  3H8C A;  3ERV A;  3KWZ A;  3KSE A;  4YYV A;  3BWK A;  1VSN A;  1PCI A;  3RNV A;  1YAL A;  2NQA A;  3BB7 A;  1PIP A;  2XU5 A;  2P7U A;  3BBA A;  4IP3 A;  4OEM A;  6PAD A;  1PPO A;  1SP4 B;  4YV8 A;  5A24 A;  3CBJ A;  3W31 A;  1NQC A;  3RVW A;  4BS6 A;  2DC8 A;  2NQG A;  4BOQ A;  1HUC B;  2NQI A;  4KLB A;  1XKG A;  4MI7 A;  2DC9 A;  3N3G A;  9PAP A;  1CPJ A;  3GCB A;  3W30 A;  4QRX A;  4PP1 A;  1TLO A;  1ZCM A;  2FRQ A;  2DJG B;  3I06 A;  4G54 A;  4CDD B;  2GHU A;  3H89 A;  2ACT A;  2DZZ A;  1CS8 A;  4YYQ A;  4REZ A;  2BU3 A;  3C0R A;  4PAD A;  4PP2 E;  3MTV A;  1ITO A;  4BOZ A;  2FQ9 A;  7PCK A;  4P16 A;  3U8E A;  3D6S A;  1DEU A;  1MEM A;  4OEL A;  2AYO A;  2ATO A;  3CH3 X; 
#chains in the Genus database with same CATH homology
 2BDL A;  4YYU A;  1AU4 A;  5J94 A;  2BDZ A;  1K3B B;  2FRA A;  4C5P A;  2DZY A;  4QRV A;  3I3T A;  3V6E A;  1GLO A;  3OVZ A;  2PBH A;  1BP4 A;  2AS8 A;  1CVZ A;  1CJL A;  1KHP A;  3K24 A;  3S3R A;  1U9W A;  1AEC A;  1Y08 A;  2YJ8 A;  2AU1 A;  3F75 A;  2AUX A;  4MZO A;  1GX3 A;  3PNR A;  2JQF R;  3F5V A;  3CH2 X;  2JQG R;  4HWY A;  4YYR A;  1AU3 A;  4X6I A;  2IPP B;  2CIO A;  3IUT A;  3KKU A;  2OP3 A;  2AUZ A;  2XU3 A;  1AU0 A;  1BQI A;  3N4C A;  5CHT A;  1PAD A;  4XUI A;  1JQP A;  1Q6K A;  5K16 A;  4QRG A;  1CV8 A;  4QH6 A;  1YK7 A;  3RVV A;  1QMY A;  1A6R A;  3P5V A;  4GUZ A;  2E02 A;  3OF8 A;  1ZIV A;  2YJ2 A;  2G8E A;  3HD3 A;  2Y5B A;  4AXL A;  3LFY A;  5EGW A;  4N8W A;  1AU2 A;  2DC7 A;  2YJB A;  4CDE B;  4P6E A;  4B55 A;  4BQV A;  3LXS A;  2YJC A;  3E1Z B;  1ME3 A;  2XU1 A;  3HWN A;  4CDF B;  3PDF A;  2P86 A;  2C0Y A;  2R9C A;  1DF0 A;  3IOQ A;  2FUD A;  4I07 A;  1QOL A;  5EF4 A;  2HH5 A;  2FO5 A;  3PBH A;  4NV7 A;  4P6G A;  3IEJ A;  4PI3 A;  1TL9 A;  4X6J A;  2P0R A;  2DCB A;  3S3Q A;  2R6N A;  1F2B A;  4MSX A;  5JH3 A;  2DC6 A;  3B79 A;  1PE6 A;  1YVB A;  2R9N A;  1YT7 A;  4RY2 A;  2G8J A;  3P5U A;  3BC3 A;  2YJ9 A;  2O6X A;  4K7C A;  2ARY A;  3WXF A;  4DMY A;  2FT2 A;  4MZS A;  3OIS A;  3O0U A;  2DCD A;  3NHE A;  2AYN A;  2AIM A;  2DCC A;  4X6H A;  1BGO A;  4DMX A;  1PXV A;  1PBH A;  1THE A;  3H8B A;  3QT4 A;  4FK5 A;  1KXR A;  2PNS A;  4YVA A;  4I04 A;  2F1G A;  4CDC B;  3O1G A;  4N4Z A;  5FPW A;  2IBI A;  1MIR A;  3D9W A;  3RVX A;  1X9Y A;  3KFQ A;  3C9E A;  1KFX L;  1KHQ A;  3KX1 A;  1MDW A;  1W4T A;  2HXZ A;  2E01 A;  1F29 A;  3BCN A;  3ZUA A;  4NV8 A;  4W5C A;  2R9M A;  3MHS A;  3DF0 A;  3N3K A;  4Q8H A;  4CZW A;  1NLJ A;  1CB5 A;  1NB3 A;  3QJ3 A;  1PPD A;  4ZUX U;  3P5X A;  1GMY A;  2BSZ A;  3KWB X;  3H7D A;  1AYW A;  4BGF A;  1VJV A;  5CVO B;  4BSQ A;  1NL6 A;  1AYV A;  4Q8G A;  2FYE A;  3M99 A;  3BOW A;  1O0E A;  3KW9 A;  1POP A;  1CTE A;  3PW3 A;  3BPF A;  4FIP A;  1YK8 A;  1FH0 A;  2G7Y A;  3MTN A;  2HHN A;  1GCB A;  2PRE A;  3HHA A;  4BS5 A;  2XU4 A;  3K8U A;  4WA6 A;  2FTD A;  4YYS A;  2F7D A;  3OF9 A;  3QSD A;  3MHH A;  1M6D A;  4W5B A;  5PAD A;  1QXP A;  4AXM A;  1TU6 A;  1EWO A;  1KFU L;  2VHS A;  2E00 A;  1ICF A;  3BPM A;  2PAD A;  3AI8 A;  5CHV A;  3P5W A;  4YYW A;  1NPZ A;  1BY8 A;  1EWP A;  1F2C A;  3CBK A;  5F02 A;  3H6S A;  2OZ2 A;  4N79 A;  1NB5 A;  2GFO A;  1MS6 A;  2G6D A;  8PCH A;  3TNX A;  1U9V A;  1SNK A;  3HHI A;  4I05 A;  2VHF A;  1U9Q X;  3USV A;  3OVX A;  1AYU A;  1W6F A;  2B1M A;  4QBB A;  1AIM A;  1MHW A;  3WXE A;  3WXG A;  2NQD B;  2AVW A;  3IHP A;  3K9M A;  1STF E;  4FJC A;  1PPP A;  2B1N A;  2Y6E A;  2DCA A;  2HD5 A;  3IMA A;  3V6C A;  2DJF B;  1ATK A;  5CVM A;  2E03 A;  5CVN B;  3IV2 A;  1EF7 A;  1U5I A;  1IWD A;  1PPN A;  2WBF X;  3MOR A;  2R9F A;  1QDQ A;  1E2T A;  3LTW A;  1CSB B;  1GEC E;  5JA7 A;  2VFB A;  1EWM A;  2CB5 A;  2R9O A;  1W5R A;  1Y4H A;  1F2A A;  1MEG A;  2OUL A;  1CQD A;  1EWL A;  1ME4 A;  1S4V A;  4XR7 A;  1U9X A;  2H7J A;  4BPV A;  4W4U A;  3H8C A;  3ERV A;  3KWZ A;  3KSE A;  4YYV A;  3BWK A;  1VSN A;  1PCI A;  1YAL A;  2NQA A;  1PIP A;  2XU5 A;  2P7U A;  4OEM A;  6PAD A;  1PPO A;  1SP4 B;  4YV8 A;  5A24 A;  3CBJ A;  1NQC A;  3RVW A;  4BS6 A;  2DC8 A;  2NQG A;  1HUC B;  2NQI A;  4KLB A;  1XKG A;  2DC9 A;  3N3G A;  9PAP A;  1CPJ A;  3GCB A;  4QRX A;  4PP1 A;  1TLO A;  1ZCM A;  2FRQ A;  2DJG B;  3I06 A;  4G54 A;  4CDD B;  2GHU A;  3H89 A;  2ACT A;  2DZZ A;  1CS8 A;  4YYQ A;  4PAD A;  4PP2 E;  1ITO A;  7PCK A;  2FQ9 A;  2VFC A;  3U8E A;  3D6S A;  1DEU A;  1MEM A;  4OEL A;  2AYO A;  2ATO A;  3CH3 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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