3TNXA

Structure of the precursor of a thermostable variant of papain at 2.6 angstroem resolution
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
310
structure length
310
Chain Sequence
NDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIRNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of a thermostable mutant of pro-papain reveals its activation mechanism
pubmed doi rcsb
molecule tags Hydrolase
source organism Carica papaya
molecule keywords Papain
total genus 106
structure length 310
sequence length 310
chains with identical sequence C
ec nomenclature ec 3.4.22.2: Papain.
pdb deposition date 2011-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
A PF08246 Inhibitor_I29 Cathepsin propeptide inhibitor domain (I29)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3tnxA00
1X9YA 3OF8A 3OVXA 9PAPA 1CPJA 1AIMA 4KLBA 3C9EA 3KWZA 2R9NA 2DCBA 2AUZA 2DC9A 2NQDB 3P5XA 4PP1A 4BSQA 2NQIA 2H7JA 3IEJA 1F2BA 3QJ3A 1Q6KA 3CH3X 4G54A 3KW9A 1CB5A 1CQDA 3IOQA 2NQAA 1ME4A 1CJLA 2P0RA 3QT4A 4YYUA 3IV2A 2DZZA 2CB5A 1TL9A 3ZUAA 2ATOA 4I07A 3KKUA 3P5WA 2DJFB 4CZWA 1AECA 1QOLA 2YJ2A 3F75A 3N4CA 4Q8HA 1U9XA 2XU4A 2GFOA 5JA7A 1NQCA 1PPNA 2YJ9A 3I3TA 1ICFA 2AYNA 5CVNB 3D6SA 4P6EA 2FT2A 2FUDA 2HHNA 2G7YA 4FIPA 2R9CA 1EWOA 2FO5A 2YJCA 1PBHA 2JQGR 5CHTA 3HHIA 1MIRA 3F5VA 4PP2E 3B79A 2E03A 1DEUA 2PNSA 3CBKA 1STFE 2DCCA 1KHQA 2HH5A 2AU1A 3KWBX 1GCBA 4I04A 3MHHA 2R9OA 4X6JA 4XUIA 2DC8A 3WXFA 3P5UA 3PNRA 3BPMA 1QMYA 3HD3A 1ATKA 3OISA 2BDLA 3NHEA 1YK7A 3ERVA 2IPPB 1M6DA 4W5CA 2Y5BA 1PPDA 3HWNA 4X6HA 1MS6A 6PADA 1AYUA 3O0UA 3I06A 4W5BA 2CIOA 2FYEA 3MORA 3RVXA 2ARYA 1Y4HA 2P86A 4YV8A 1YK8A 4BQVA 1BGOA 1NB3A 2BDZA 1NLJA 1PXVA 4XR7A 3WXEA 1VJVA 1KFUL 4FJCA 4BS5A 2JQFR 2FQ9A 4QBBA 1K3BB 2R6NA 4X6IA 3N3KA 2AUXA 2FRAA 4QRVA 3LXSA 4WA6A 4N4ZA 1EWPA 3K9MA 2DCDA 1EWMA 4OEMA 1POPA 3RVWA 2HXZA 1O0EA 4FK5A 1QDQA 2XU3A 1TU6A 1SNKA 4DMXA 3IMAA 2E02A 1GECE 2VHFA 5CVMA 3AI8A 4CDCB 1PPPA 1XKGA 3E1ZB 3N3GA 3MHSA 5A24A 1GLOA 2XU1A 5CVOB 1F2CA 1CV8A 4BPVA 2AIMA 1PCIA 3HHAA 3P5VA 2DZYA 1MDWA 3PDFA 3BPFA 2OZ2A 5CHVA 3O1GA 1ZCMA 4OELA 3H6SA 3M99A 1YT7A 3OVZA 1F2AA 2OP3A 4CDDB 1ME3A 1YVBA 4MSXA 4CDEB 4MZSA 2DCAA 2G8JA 4W4UA 1AU3A 4HWYA 1BQIA 1AU4A 2OULA 4QRXA 3USVA 2G8EA 3V6CA 2F1GA 1KXRA 3BCNA 2E00A 3IHPA 2XU5A 3CH2X 4I05A 2FTDA 1NL6A 2GHUA 2YJBA 3LFYA 2VHSA 4Q8GA 4RY2A 1CTEA 1NPZA 1PE6A 1FH0A 5EGWA 3RVVA 5JH3A 2DC6A 2G6DA 3H89A 2FRQA 2PBHA 1VSNA 4YYVA 4YYQA 1THEA 2WBFX 3BWKA 4N8WA 1NB5A 1KFXL 2HD5A 3S3RA 2B1NA 3H8CA 1DF0A 5K16A 1HUCB 2AYOA 1ZIVA 2ACTA 1JQPA 2E01A 2YJ8A 3PW3A 2PREA 4YYWA 5EF4A 2R9MA 3KFQA 1MEMA 4DMYA 8PCHA 5J94A 1S4VA 4PI3A 1A6RA 1QXPA 3BOWA 3QSDA 2Y6EA 2R9FA 3PBHA 4YYSA 1U9VA 3TNXA 3BC3A 4YVAA 2IBIA 1PIPA 3WXGA 1AU0A 2O6XA 1PPOA 3S3QA 1IWDA 1BY8A 3V6EA 1PADA 1AYVA 1MHWA 3GCBA 1GMYA 4QRGA 1CS8A 3U8EA 1CVZA 2P7UA 2B1MA 2C0YA 3H8BA 4ZUXU 1ITOA 2F7DA 4N79A 3OF9A 1U5IA 3IUTA 4PADA 1TLOA 1MEGA 1BP4A 4YYRA 3MTNA 1Y08A 3KX1A 2AS8A 2DJGB 3H7DA 1U9WA 2AVWA 1CSBB 1SP4B 5F02A 1F29A 2DC7A 3K24A 4AXMA 2PADA 1AU2A 1EWLA 5PADA 3CBJA 3DF0A 1AYWA 4MZOA 1KHPA 1YALA 3K8UA 7PCKA 1U9QX 3KSEA 4AXLA 4CDFB 5FPWA 1EF7A 4K7CA 2NQGA 4BS6A 4QH6A 4P6GA
chains in the Genus database with same CATH superfamily
1X9YA 3OF8A 3OVXA 4MM3B 9PAPA 3PHUA 1CPJA 1AIMA 4KLBA 4IUMA 4D8EA 3C9EA 3KWZA 2R9NA 2DCBA 2AUZA 2DC9A 2NQDB 3P5XA 4PP1A 4BSQA 2NQIA 2H7JA 4A5UA 3IEJA 1F2BA 3QJ3A 1Q6KA 3CH3X 5KO3A 4G54A 3KW9A 1CB5A 1CQDA 3IOQA 2NQAA 1ME4A 1CJLA 2P0RA 3QT4A 4YYUA 3IV2A 2DZZA 2CB5A 1TL9A 3ZUAA 2ATOA 4I07A 3KKUA 3P5WA 2DJFB 4CZWA 1AECA 1QOLA 2YJ2A 3F75A 2BU3A 3N4CA 4Q8HA 1U9XA 4HXDB 3TRKA 2XU4A 3PHWA 2GFOA 5JA7A 1NQCA 1PPNA 2YJ9A 3I3TA 1ICFA 2AYNA 5CVNB 3D6SA 2J7QA 4P6EA 3MTVA 4BOZA 2FT2A 2FUDA 2HHNA 2G7YA 4FIPA 2R9CA 1EWOA 2FO5A 2YJCA 1PBHA 3PHXA 2JQGR 5CHTA 3HHIA 1MIRA 3F5VA 3O65A 4PP2E 3B79A 2E03A 1DEUA 1UKFA 2PNSA 3CBKA 1STFE 4BOQA 2DCCA 1KHQA 2HH5A 2AU1A 3KWBX 1GCBA 4I04A 3MHHA 2R9OA 4X6JA 2FE8A 4XUIA 2DC8A 3WXFA 3P5UA 3C0RA 3PNRA 4BOPA 3BPMA 1QMYA 3HD3A 1ATKA 3OISA 2BDLA 3NHEA 1YK7A 3PRMA 3ERVA 2IPPB 1M6DA 4W5CA 2Y5BA 3MJ5A 1PPDA 3HWNA 3MP2A 4X6HA 1MS6A 6PADA 1AYUA 3O0UA 3I06A 4W5BA 2CIOA 4BOUA 5E6JA 2FYEA 3MORA 2J7QC 3RVXA 2ARYA 1Y4HA 2P86A 4YV8A 4D8IA 3IFUA 1YK8A 4BQVA 1BGOA 1NB3A 2BDZA 1NLJA 1PXVA 3PT2A 4XR7A 3B21A 2JRIA 3WXEA 1VJVA 1KFUL 4FJCA 4BS5A 2JQFR 2FQ9A 4QBBA 1K3BB 2R6NA 4X6IA 3N3KA 2AUXA 2FRAA 4QRVA 3LXSA 4WA6A 4N4ZA 1EWPA 3K9MA 2DCDA 1EWMA 4OW0A 4OEMA 1POPA 3RVWA 2HXZA 1O0EA 4FK5A 1QDQA 2XU3A 1TU6A 1SNKA 4DMXA 3IMAA 2E02A 4RF1A 1GECE 2VHFA 5CVMA 3AI8A 4CDCB 1PPPA 1XKGA 3E1ZB 3N3GA 3MHSA 5A24A 1GLOA 2XU1A 5CVOB 1F2CA 2BTWA 1CV8A 4BPVA 2AIMA 1PCIA 3HHAA 3P5VA 2DZYA 1MDWA 3PDFA 3BPFA 3ZNHA 2OZ2A 5CHVA 3O1GA 4MI7A 1ZCMA 4OELA 3H6SA 3M99A 1YT7A 3PRPA 3OVZA 1YZBA 2DOSA 1F2AA 2OP3A 4CDDB 1ME3A 1YVBA 4MSXA 4CDEB 4MZSA 2DCAA 2G8JA 5JZEA 4W4UA 1AU3A 4OVZA 4HWYA 1BQIA 1AU4A 2OULA 4QRXA 3USVA 5EZSA 2G8EA 3V6CA 4OVZB 2F1GA 1KXRA 4IP3A 3BCNA 2E00A 3IHPA 2XU5A 3CH2X 5EZQA 4I05A 2FTDA 1NL6A 2GHUA 2YJBA 4M0WA 3LFYA 2VHSA 4Q8GA 4RY2A 1CTEA 1NPZA 4ZTBA 1PE6A 1FH0A 5EGWA 3RVVA 5JH3A 2DC6A 2G6DA 3H89A 3OQCA 2UZJA 2FRQA 2PBHA 1VSNA 2AGAA 4YYVA 4YYQA 1THEA 2WBFX 3BWKA 4N8WA 3TMPA 1NB5A 1KFXL 2HD5A 3E9SA 3S3RA 2B1NA 3H8CA 1DF0A 5K16A 1HUCB 2AYOA 1ZIVA 4D8BA 2ACTA 1JQPA 2E01A 2YJ8A 3PW3A 2PREA 4YYWA 5EF4A 2R9MA 3KFQA 1MEMA 4DMYA 2Z84A 8PCHA 5J94A 1S4VA 4PI3A 1A6RA 1QXPA 3BOWA 4P16A 3QSDA 4XZXA 2Y6EA 2R9FA 3PBHA 4YYSA 1U9VA 2BTWB 3TNXA 4RNAA 3BC3A 4R3DA 4YVAA 2IBIA 1PIPA 3WXGA 1AU0A 2O6XA 4GUAA 1PPOA 3S3QA 1IWDA 1BY8A 3V6EA 1PADA 1AYVA 4BOSA 1MHWA 3GCBA 1GMYA 3BBAA 4QRGA 2HWKA 1CS8A 3U8EA 1CVZA 2P7UA 2B1MA 2C0YA 2JTCA 4REZA 3H8BA 4ZUXU 1ITOA 2F7DA 4N79A 4RKXA 3OF9A 3BY4A 1U5IA 3IUTA 4PADA 1TLOA 1MEGA 1BP4A 4YYRA 3MTNA 1Y08A 4PT5A 3KX1A 2AS8A 2DJGB 3H7DA 4RF0A 1U9WA 2AVWA 1DKIA 1CSBB 1SP4B 5F02A 1F29A 2DC7A 4WURA 3K24A 4AXMA 3W30A 2PADA 3PSEA 1AU2A 1EWLA 5PADA 3CBJA 3DF0A 3BB7A 1AYWA 4MZOA 1KHPA 1YALA 3K8UA 3W31A 7PCKA 1U9QX 3KSEA 4AXLA 4CDFB 5FPWA 1EF7A 4K7CA 2NQGA 4BS6A 4QH6A 1PVJA 3RNVA 4P6GA
chains in the Genus database with same CATH topology
1X9YA 3OF8A 3OVXA 9PAPA 1CPJA 1AIMA 4KLBA 3C9EA 3KWZA 2R9NA 2DCBA 2AUZA 2DC9A 2NQDB 3P5XA 4PP1A 4BSQA 2NQIA 2H7JA 3IEJA 1F2BA 3QJ3A 1Q6KA 3CH3X 4G54A 3KW9A 1CB5A 1CQDA 3IOQA 2NQAA 1ME4A 1CJLA 2P0RA 3QT4A 4YYUA 3IV2A 2DZZA 2CB5A 1TL9A 3ZUAA 2ATOA 4I07A 3KKUA 3P5WA 2DJFB 4CZWA 1AECA 1QOLA 2YJ2A 3F75A 3N4CA 4Q8HA 1U9XA 2XU4A 2GFOA 5JA7A 1NQCA 1PPNA 2YJ9A 3I3TA 1ICFA 2AYNA 5CVNB 3D6SA 4P6EA 2FT2A 2FUDA 2HHNA 2G7YA 4FIPA 2R9CA 1EWOA 2FO5A 2YJCA 1PBHA 1GX3A 2JQGR 5CHTA 3HHIA 1MIRA 3F5VA 4PP2E 3B79A 2E03A 1DEUA 2PNSA 3CBKA 1STFE 2DCCA 1KHQA 2HH5A 2AU1A 3KWBX 1GCBA 4I04A 3MHHA 2R9OA 4X6JA 4XUIA 2DC8A 3WXFA 3P5UA 3PNRA 3BPMA 1QMYA 3HD3A 1ATKA 3OISA 2BDLA 3NHEA 1YK7A 3ERVA 2IPPB 1M6DA 4W5CA 2Y5BA 1PPDA 3HWNA 4X6HA 1MS6A 6PADA 1AYUA 4B55A 3O0UA 3I06A 4W5BA 2CIOA 2BSZA 2FYEA 3MORA 4C5PA 3RVXA 2ARYA 1Y4HA 2P86A 4YV8A 1YK8A 4BQVA 1BGOA 1NB3A 2BDZA 1NLJA 1PXVA 4XR7A 3WXEA 1VJVA 1KFUL 4FJCA 4BS5A 2JQFR 2FQ9A 4QBBA 1K3BB 2R6NA 4X6IA 3N3KA 2AUXA 2FRAA 4QRVA 3LXSA 4WA6A 4N4ZA 1EWPA 3K9MA 2DCDA 1EWMA 4OEMA 1POPA 3RVWA 2HXZA 1O0EA 4FK5A 1QDQA 2XU3A 1TU6A 1SNKA 4DMXA 3IMAA 2E02A 1GECE 2VHFA 5CVMA 3AI8A 4CDCB 1PPPA 1XKGA 3E1ZB 3N3GA 3MHSA 5A24A 1GLOA 2XU1A 5CVOB 1F2CA 1CV8A 4BPVA 2AIMA 1PCIA 3HHAA 3P5VA 2DZYA 1MDWA 3PDFA 3BPFA 2OZ2A 5CHVA 3O1GA 1ZCMA 4OELA 3H6SA 3M99A 1YT7A 3OVZA 1F2AA 2OP3A 4CDDB 1ME3A 1YVBA 4MSXA 4CDEB 4MZSA 1E2TA 2DCAA 2G8JA 4W4UA 1AU3A 4HWYA 1BQIA 1AU4A 2OULA 4QRXA 3USVA 2G8EA 3V6CA 2F1GA 1KXRA 3BCNA 2E00A 3D9WA 3IHPA 2XU5A 3CH2X 4I05A 2FTDA 1NL6A 2GHUA 2YJBA 3LFYA 2VHSA 4Q8GA 4RY2A 1CTEA 1NPZA 1PE6A 1FH0A 5EGWA 3RVVA 5JH3A 1W4TA 2DC6A 2G6DA 3H89A 2FRQA 2PBHA 1VSNA 4YYVA 4YYQA 1THEA 2WBFX 3BWKA 4N8WA 1NB5A 1KFXL 2HD5A 3LTWA 3S3RA 4NV8A 2B1NA 3H8CA 1DF0A 5K16A 1HUCB 2AYOA 1ZIVA 2ACTA 1JQPA 2E01A 2YJ8A 3PW3A 2PREA 4YYWA 5EF4A 2R9MA 3KFQA 1MEMA 4DMYA 8PCHA 5J94A 1S4VA 4PI3A 1A6RA 1QXPA 3BOWA 3QSDA 2Y6EA 2R9FA 3PBHA 4YYSA 1U9VA 3TNXA 2VFBA 3BC3A 4NV7A 4YVAA 2IBIA 1PIPA 3WXGA 1AU0A 2VFCA 2O6XA 4GUZA 1PPOA 3S3QA 1IWDA 1BY8A 3V6EA 1PADA 1AYVA 1W5RA 1W6FA 1MHWA 3GCBA 1GMYA 4BGFA 4QRGA 1CS8A 3U8EA 1CVZA 2P7UA 2B1MA 2C0YA 3H8BA 4ZUXU 1ITOA 2F7DA 4N79A 3OF9A 1U5IA 3IUTA 4PADA 1TLOA 1MEGA 1BP4A 4YYRA 3MTNA 1Y08A 3KX1A 2AS8A 2DJGB 3H7DA 1U9WA 2AVWA 1CSBB 1SP4B 5F02A 1F29A 2DC7A 3K24A 4AXMA 2PADA 1AU2A 1EWLA 5PADA 3CBJA 3DF0A 1AYWA 4MZOA 1KHPA 1YALA 3K8UA 7PCKA 1U9QX 3KSEA 4AXLA 4CDFB 5FPWA 1EF7A 4K7CA 2NQGA 4BS6A 4QH6A 4P6GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X9Y A;  3OF8 A;  3OVX A;  9PAP A;  1CPJ A;  1AIM A;  4KLB A;  3C9E A;  3KWZ A;  2R9N A;  2DCB A;  2AUZ A;  2DC9 A;  2NQD B;  3P5X A;  4PP1 A;  4BSQ A;  2NQI A;  2H7J A;  3IEJ A;  1F2B A;  3QJ3 A;  1Q6K A;  3CH3 X;  4G54 A;  3KW9 A;  1CB5 A;  1CQD A;  3IOQ A;  2NQA A;  1ME4 A;  1CJL A;  2P0R A;  3QT4 A;  4YYU A;  3IV2 A;  2DZZ A;  2CB5 A;  1TL9 A;  3ZUA A;  2ATO A;  4I07 A;  3KKU A;  3P5W A;  2DJF B;  4CZW A;  1AEC A;  1QOL A;  2YJ2 A;  3F75 A;  3N4C A;  4Q8H A;  1U9X A;  2XU4 A;  2GFO A;  5JA7 A;  1NQC A;  1PPN A;  2YJ9 A;  3I3T A;  1ICF A;  2AYN A;  5CVN B;  3D6S A;  4P6E A;  2FT2 A;  2FUD A;  2HHN A;  2G7Y A;  4FIP A;  2R9C A;  1EWO A;  2FO5 A;  2YJC A;  1PBH A;  2JQG R;  5CHT A;  3HHI A;  1MIR A;  3F5V A;  4PP2 E;  3B79 A;  2E03 A;  1DEU A;  2PNS A;  3CBK A;  1STF E;  2DCC A;  1KHQ A;  2HH5 A;  2AU1 A;  3KWB X;  1GCB A;  4I04 A;  3MHH A;  2R9O A;  4X6J A;  4XUI A;  2DC8 A;  3WXF A;  3P5U A;  3PNR A;  3BPM A;  1QMY A;  3HD3 A;  1ATK A;  3OIS A;  2BDL A;  3NHE A;  1YK7 A;  3ERV A;  2IPP B;  1M6D A;  4W5C A;  2Y5B A;  1PPD A;  3HWN A;  4X6H A;  1MS6 A;  6PAD A;  1AYU A;  3O0U A;  3I06 A;  4W5B A;  2CIO A;  2FYE A;  3MOR A;  3RVX A;  2ARY A;  1Y4H A;  2P86 A;  4YV8 A;  1YK8 A;  4BQV A;  1BGO A;  1NB3 A;  2BDZ A;  1NLJ A;  1PXV A;  4XR7 A;  3WXE A;  1VJV A;  1KFU L;  4FJC A;  4BS5 A;  2JQF R;  2FQ9 A;  4QBB A;  1K3B B;  2R6N A;  4X6I A;  3N3K A;  2AUX A;  2FRA A;  4QRV A;  3LXS A;  4WA6 A;  4N4Z A;  1EWP A;  3K9M A;  2DCD A;  1EWM A;  4OEM A;  1POP A;  3RVW A;  2HXZ A;  1O0E A;  4FK5 A;  1QDQ A;  2XU3 A;  1TU6 A;  1SNK A;  4DMX A;  3IMA A;  2E02 A;  1GEC E;  2VHF A;  5CVM A;  3AI8 A;  4CDC B;  1PPP A;  1XKG A;  3E1Z B;  3N3G A;  3MHS A;  5A24 A;  1GLO A;  2XU1 A;  5CVO B;  1F2C A;  1CV8 A;  4BPV A;  2AIM A;  1PCI A;  3HHA A;  3P5V A;  2DZY A;  1MDW A;  3PDF A;  3BPF A;  2OZ2 A;  5CHV A;  3O1G A;  1ZCM A;  4OEL A;  3H6S A;  3M99 A;  1YT7 A;  3OVZ A;  1F2A A;  2OP3 A;  4CDD B;  1ME3 A;  1YVB A;  4MSX A;  4CDE B;  4MZS A;  2DCA A;  2G8J A;  4W4U A;  1AU3 A;  4HWY A;  1BQI A;  1AU4 A;  2OUL A;  4QRX A;  3USV A;  2G8E A;  3V6C A;  2F1G A;  1KXR A;  3BCN A;  2E00 A;  3IHP A;  2XU5 A;  3CH2 X;  4I05 A;  2FTD A;  1NL6 A;  2GHU A;  2YJB A;  3LFY A;  2VHS A;  4Q8G A;  4RY2 A;  1CTE A;  1NPZ A;  1PE6 A;  1FH0 A;  5EGW A;  3RVV A;  5JH3 A;  2DC6 A;  2G6D A;  3H89 A;  2FRQ A;  2PBH A;  1VSN A;  4YYV A;  4YYQ A;  1THE A;  2WBF X;  3BWK A;  4N8W A;  1NB5 A;  1KFX L;  2HD5 A;  3S3R A;  2B1N A;  3H8C A;  1DF0 A;  5K16 A;  1HUC B;  2AYO A;  1ZIV A;  2ACT A;  1JQP A;  2E01 A;  2YJ8 A;  3PW3 A;  2PRE A;  4YYW A;  5EF4 A;  2R9M A;  3KFQ A;  1MEM A;  4DMY A;  8PCH A;  5J94 A;  1S4V A;  4PI3 A;  1A6R A;  1QXP A;  3BOW A;  3QSD A;  2Y6E A;  2R9F A;  3PBH A;  4YYS A;  1U9V A;  3TNX A;  3BC3 A;  4YVA A;  2IBI A;  1PIP A;  3WXG A;  1AU0 A;  2O6X A;  1PPO A;  3S3Q A;  1IWD A;  1BY8 A;  3V6E A;  1PAD A;  1AYV A;  1MHW A;  3GCB A;  1GMY A;  4QRG A;  1CS8 A;  3U8E A;  1CVZ A;  2P7U A;  2B1M A;  2C0Y A;  3H8B A;  4ZUX U;  1ITO A;  2F7D A;  4N79 A;  3OF9 A;  1U5I A;  3IUT A;  4PAD A;  1TLO A;  1MEG A;  1BP4 A;  4YYR A;  3MTN A;  1Y08 A;  3KX1 A;  2AS8 A;  2DJG B;  3H7D A;  1U9W A;  2AVW A;  1CSB B;  1SP4 B;  5F02 A;  1F29 A;  2DC7 A;  3K24 A;  4AXM A;  2PAD A;  1AU2 A;  1EWL A;  5PAD A;  3CBJ A;  3DF0 A;  1AYW A;  4MZO A;  1KHP A;  1YAL A;  3K8U A;  7PCK A;  1U9Q X;  3KSE A;  4AXL A;  4CDF B;  5FPW A;  1EF7 A;  4K7C A;  2NQG A;  4BS6 A;  4QH6 A;  4P6G A; 
#chains in the Genus database with same CATH topology
 1X9Y A;  3OF8 A;  3OVX A;  4MM3 B;  9PAP A;  3PHU A;  1CPJ A;  1AIM A;  4KLB A;  4IUM A;  4D8E A;  3C9E A;  3KWZ A;  2R9N A;  2DCB A;  2AUZ A;  2DC9 A;  2NQD B;  3P5X A;  4PP1 A;  4BSQ A;  2NQI A;  2H7J A;  4A5U A;  3IEJ A;  1F2B A;  3QJ3 A;  1Q6K A;  3CH3 X;  5KO3 A;  4G54 A;  3KW9 A;  1CB5 A;  1CQD A;  3IOQ A;  2NQA A;  1ME4 A;  1CJL A;  2P0R A;  3QT4 A;  4YYU A;  3IV2 A;  2DZZ A;  2CB5 A;  1TL9 A;  3ZUA A;  2ATO A;  4I07 A;  3KKU A;  3P5W A;  2DJF B;  4CZW A;  1AEC A;  1QOL A;  2YJ2 A;  3F75 A;  2BU3 A;  3N4C A;  4Q8H A;  1U9X A;  4HXD B;  3TRK A;  2XU4 A;  3PHW A;  2GFO A;  5JA7 A;  1NQC A;  1PPN A;  2YJ9 A;  3I3T A;  1ICF A;  2AYN A;  5CVN B;  3D6S A;  2J7Q A;  4P6E A;  3MTV A;  4BOZ A;  2FT2 A;  2FUD A;  2HHN A;  2G7Y A;  4FIP A;  2R9C A;  1EWO A;  2FO5 A;  2YJC A;  1PBH A;  3PHX A;  2JQG R;  5CHT A;  3HHI A;  1MIR A;  3F5V A;  3O65 A;  4PP2 E;  3B79 A;  2E03 A;  1DEU A;  1UKF A;  2PNS A;  3CBK A;  1STF E;  4BOQ A;  2DCC A;  1KHQ A;  2HH5 A;  2AU1 A;  3KWB X;  1GCB A;  4I04 A;  3MHH A;  2R9O A;  4X6J A;  2FE8 A;  4XUI A;  2DC8 A;  3WXF A;  3P5U A;  3C0R A;  3PNR A;  4BOP A;  3BPM A;  1QMY A;  3HD3 A;  1ATK A;  3OIS A;  2BDL A;  3NHE A;  1YK7 A;  3PRM A;  3ERV A;  2IPP B;  1M6D A;  4W5C A;  2Y5B A;  3MJ5 A;  1PPD A;  3HWN A;  3MP2 A;  4X6H A;  1MS6 A;  6PAD A;  1AYU A;  3O0U A;  3I06 A;  4W5B A;  2CIO A;  4BOU A;  5E6J A;  2FYE A;  3MOR A;  2J7Q C;  3RVX A;  2ARY A;  1Y4H A;  2P86 A;  4YV8 A;  4D8I A;  3IFU A;  1YK8 A;  4BQV A;  1BGO A;  1NB3 A;  2BDZ A;  1NLJ A;  1PXV A;  3PT2 A;  4XR7 A;  3B21 A;  2JRI A;  3WXE A;  1VJV A;  1KFU L;  4FJC A;  4BS5 A;  2JQF R;  2FQ9 A;  4QBB A;  1K3B B;  2R6N A;  4X6I A;  3N3K A;  2AUX A;  2FRA A;  4QRV A;  3LXS A;  4WA6 A;  4N4Z A;  1EWP A;  3K9M A;  2DCD A;  1EWM A;  4OW0 A;  4OEM A;  1POP A;  3RVW A;  2HXZ A;  1O0E A;  4FK5 A;  1QDQ A;  2XU3 A;  1TU6 A;  1SNK A;  4DMX A;  3IMA A;  2E02 A;  4RF1 A;  1GEC E;  2VHF A;  5CVM A;  3AI8 A;  4CDC B;  1PPP A;  1XKG A;  3E1Z B;  3N3G A;  3MHS A;  5A24 A;  1GLO A;  2XU1 A;  5CVO B;  1F2C A;  2BTW A;  1CV8 A;  4BPV A;  2AIM A;  1PCI A;  3HHA A;  3P5V A;  2DZY A;  1MDW A;  3PDF A;  3BPF A;  3ZNH A;  2OZ2 A;  5CHV A;  3O1G A;  4MI7 A;  1ZCM A;  4OEL A;  3H6S A;  3M99 A;  1YT7 A;  3PRP A;  3OVZ A;  1YZB A;  2DOS A;  1F2A A;  2OP3 A;  4CDD B;  1ME3 A;  1YVB A;  4MSX A;  4CDE B;  4MZS A;  2DCA A;  2G8J A;  5JZE A;  4W4U A;  1AU3 A;  4OVZ A;  4HWY A;  1BQI A;  1AU4 A;  2OUL A;  4QRX A;  3USV A;  5EZS A;  2G8E A;  3V6C A;  4OVZ B;  2F1G A;  1KXR A;  4IP3 A;  3BCN A;  2E00 A;  3IHP A;  2XU5 A;  3CH2 X;  5EZQ A;  4I05 A;  2FTD A;  1NL6 A;  2GHU A;  2YJB A;  4M0W A;  3LFY A;  2VHS A;  4Q8G A;  4RY2 A;  1CTE A;  1NPZ A;  4ZTB A;  1PE6 A;  1FH0 A;  5EGW A;  3RVV A;  5JH3 A;  2DC6 A;  2G6D A;  3H89 A;  3OQC A;  2UZJ A;  2FRQ A;  2PBH A;  1VSN A;  2AGA A;  4YYV A;  4YYQ A;  1THE A;  2WBF X;  3BWK A;  4N8W A;  3TMP A;  1NB5 A;  1KFX L;  2HD5 A;  3E9S A;  3S3R A;  2B1N A;  3H8C A;  1DF0 A;  5K16 A;  1HUC B;  2AYO A;  1ZIV A;  4D8B A;  2ACT A;  1JQP A;  2E01 A;  2YJ8 A;  3PW3 A;  2PRE A;  4YYW A;  5EF4 A;  2R9M A;  3KFQ A;  1MEM A;  4DMY A;  2Z84 A;  8PCH A;  5J94 A;  1S4V A;  4PI3 A;  1A6R A;  1QXP A;  3BOW A;  4P16 A;  3QSD A;  4XZX A;  2Y6E A;  2R9F A;  3PBH A;  4YYS A;  1U9V A;  2BTW B;  3TNX A;  4RNA A;  3BC3 A;  4R3D A;  4YVA A;  2IBI A;  1PIP A;  3WXG A;  1AU0 A;  2O6X A;  4GUA A;  1PPO A;  3S3Q A;  1IWD A;  1BY8 A;  3V6E A;  1PAD A;  1AYV A;  4BOS A;  1MHW A;  3GCB A;  1GMY A;  3BBA A;  4QRG A;  2HWK A;  1CS8 A;  3U8E A;  1CVZ A;  2P7U A;  2B1M A;  2C0Y A;  2JTC A;  4REZ A;  3H8B A;  4ZUX U;  1ITO A;  2F7D A;  4N79 A;  4RKX A;  3OF9 A;  3BY4 A;  1U5I A;  3IUT A;  4PAD A;  1TLO A;  1MEG A;  1BP4 A;  4YYR A;  3MTN A;  1Y08 A;  4PT5 A;  3KX1 A;  2AS8 A;  2DJG B;  3H7D A;  4RF0 A;  1U9W A;  2AVW A;  1DKI A;  1CSB B;  1SP4 B;  5F02 A;  1F29 A;  2DC7 A;  4WUR A;  3K24 A;  4AXM A;  3W30 A;  2PAD A;  3PSE A;  1AU2 A;  1EWL A;  5PAD A;  3CBJ A;  3DF0 A;  3BB7 A;  1AYW A;  4MZO A;  1KHP A;  1YAL A;  3K8U A;  3W31 A;  7PCK A;  1U9Q X;  3KSE A;  4AXL A;  4CDF B;  5FPW A;  1EF7 A;  4K7C A;  2NQG A;  4BS6 A;  4QH6 A;  1PVJ A;  3RNV A;  4P6G A; 
#chains in the Genus database with same CATH homology
 1X9Y A;  3OF8 A;  3OVX A;  9PAP A;  1CPJ A;  1AIM A;  4KLB A;  3C9E A;  3KWZ A;  2R9N A;  2DCB A;  2AUZ A;  2DC9 A;  2NQD B;  3P5X A;  4PP1 A;  4BSQ A;  2NQI A;  2H7J A;  3IEJ A;  1F2B A;  3QJ3 A;  1Q6K A;  3CH3 X;  4G54 A;  3KW9 A;  1CB5 A;  1CQD A;  3IOQ A;  2NQA A;  1ME4 A;  1CJL A;  2P0R A;  3QT4 A;  4YYU A;  3IV2 A;  2DZZ A;  2CB5 A;  1TL9 A;  3ZUA A;  2ATO A;  4I07 A;  3KKU A;  3P5W A;  2DJF B;  4CZW A;  1AEC A;  1QOL A;  2YJ2 A;  3F75 A;  3N4C A;  4Q8H A;  1U9X A;  2XU4 A;  2GFO A;  5JA7 A;  1NQC A;  1PPN A;  2YJ9 A;  3I3T A;  1ICF A;  2AYN A;  5CVN B;  3D6S A;  4P6E A;  2FT2 A;  2FUD A;  2HHN A;  2G7Y A;  4FIP A;  2R9C A;  1EWO A;  2FO5 A;  2YJC A;  1PBH A;  1GX3 A;  2JQG R;  5CHT A;  3HHI A;  1MIR A;  3F5V A;  4PP2 E;  3B79 A;  2E03 A;  1DEU A;  2PNS A;  3CBK A;  1STF E;  2DCC A;  1KHQ A;  2HH5 A;  2AU1 A;  3KWB X;  1GCB A;  4I04 A;  3MHH A;  2R9O A;  4X6J A;  4XUI A;  2DC8 A;  3WXF A;  3P5U A;  3PNR A;  3BPM A;  1QMY A;  3HD3 A;  1ATK A;  3OIS A;  2BDL A;  3NHE A;  1YK7 A;  3ERV A;  2IPP B;  1M6D A;  4W5C A;  2Y5B A;  1PPD A;  3HWN A;  4X6H A;  1MS6 A;  6PAD A;  1AYU A;  4B55 A;  3O0U A;  3I06 A;  4W5B A;  2CIO A;  2BSZ A;  2FYE A;  3MOR A;  4C5P A;  3RVX A;  2ARY A;  1Y4H A;  2P86 A;  4YV8 A;  1YK8 A;  4BQV A;  1BGO A;  1NB3 A;  2BDZ A;  1NLJ A;  1PXV A;  4XR7 A;  3WXE A;  1VJV A;  1KFU L;  4FJC A;  4BS5 A;  2JQF R;  2FQ9 A;  4QBB A;  1K3B B;  2R6N A;  4X6I A;  3N3K A;  2AUX A;  2FRA A;  4QRV A;  3LXS A;  4WA6 A;  4N4Z A;  1EWP A;  3K9M A;  2DCD A;  1EWM A;  4OEM A;  1POP A;  3RVW A;  2HXZ A;  1O0E A;  4FK5 A;  1QDQ A;  2XU3 A;  1TU6 A;  1SNK A;  4DMX A;  3IMA A;  2E02 A;  1GEC E;  2VHF A;  5CVM A;  3AI8 A;  4CDC B;  1PPP A;  1XKG A;  3E1Z B;  3N3G A;  3MHS A;  5A24 A;  1GLO A;  2XU1 A;  5CVO B;  1F2C A;  1CV8 A;  4BPV A;  2AIM A;  1PCI A;  3HHA A;  3P5V A;  2DZY A;  1MDW A;  3PDF A;  3BPF A;  2OZ2 A;  5CHV A;  3O1G A;  1ZCM A;  4OEL A;  3H6S A;  3M99 A;  1YT7 A;  3OVZ A;  1F2A A;  2OP3 A;  4CDD B;  1ME3 A;  1YVB A;  4MSX A;  4CDE B;  4MZS A;  1E2T A;  2DCA A;  2G8J A;  4W4U A;  1AU3 A;  4HWY A;  1BQI A;  1AU4 A;  2OUL A;  4QRX A;  3USV A;  2G8E A;  3V6C A;  2F1G A;  1KXR A;  3BCN A;  2E00 A;  3D9W A;  3IHP A;  2XU5 A;  3CH2 X;  4I05 A;  2FTD A;  1NL6 A;  2GHU A;  2YJB A;  3LFY A;  2VHS A;  4Q8G A;  4RY2 A;  1CTE A;  1NPZ A;  1PE6 A;  1FH0 A;  5EGW A;  3RVV A;  5JH3 A;  1W4T A;  2DC6 A;  2G6D A;  3H89 A;  2FRQ A;  2PBH A;  1VSN A;  4YYV A;  4YYQ A;  1THE A;  2WBF X;  3BWK A;  4N8W A;  1NB5 A;  1KFX L;  2HD5 A;  3LTW A;  3S3R A;  4NV8 A;  2B1N A;  3H8C A;  1DF0 A;  5K16 A;  1HUC B;  2AYO A;  1ZIV A;  2ACT A;  1JQP A;  2E01 A;  2YJ8 A;  3PW3 A;  2PRE A;  4YYW A;  5EF4 A;  2R9M A;  3KFQ A;  1MEM A;  4DMY A;  8PCH A;  5J94 A;  1S4V A;  4PI3 A;  1A6R A;  1QXP A;  3BOW A;  3QSD A;  2Y6E A;  2R9F A;  3PBH A;  4YYS A;  1U9V A;  3TNX A;  2VFB A;  3BC3 A;  4NV7 A;  4YVA A;  2IBI A;  1PIP A;  3WXG A;  1AU0 A;  2VFC A;  2O6X A;  4GUZ A;  1PPO A;  3S3Q A;  1IWD A;  1BY8 A;  3V6E A;  1PAD A;  1AYV A;  1W5R A;  1W6F A;  1MHW A;  3GCB A;  1GMY A;  4BGF A;  4QRG A;  1CS8 A;  3U8E A;  1CVZ A;  2P7U A;  2B1M A;  2C0Y A;  3H8B A;  4ZUX U;  1ITO A;  2F7D A;  4N79 A;  3OF9 A;  1U5I A;  3IUT A;  4PAD A;  1TLO A;  1MEG A;  1BP4 A;  4YYR A;  3MTN A;  1Y08 A;  3KX1 A;  2AS8 A;  2DJG B;  3H7D A;  1U9W A;  2AVW A;  1CSB B;  1SP4 B;  5F02 A;  1F29 A;  2DC7 A;  3K24 A;  4AXM A;  2PAD A;  1AU2 A;  1EWL A;  5PAD A;  3CBJ A;  3DF0 A;  1AYW A;  4MZO A;  1KHP A;  1YAL A;  3K8U A;  7PCK A;  1U9Q X;  3KSE A;  4AXL A;  4CDF B;  5FPW A;  1EF7 A;  4K7C A;  2NQG A;  4BS6 A;  4QH6 A;  4P6G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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