3BPFA

Crystal structure of falcipain-2 with its inhibitor, e64
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
241
structure length
236
Chain Sequence
QMNYEEVIKKYRGEENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGECGDQLNHAVMLVGFGMKEIVNGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of falcipain-2 and falcipain-3 bound to small molecule inhibitors: implications for substrate specificity.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Cysteine protease falcipain-2
total genus 62
structure length 236
sequence length 241
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.-:
pdb deposition date 2007-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3bpfA00
1ZIVA 5J94A 1BY8A 3H8CA 3KX1A 2AUXA 1CJLA 4N8WA 1EWPA 3NHEA 1AIMA 3IMAA 4FJCA 4MZSA 2AIMA 3CBJA 1FH0A 3KKUA 1Y4HA 1MS6A 3O1GA 4Q8HA 1F2AA 1YVBA 3HWNA 4MZOA 4ZUXU 1O0EA 2JQGR 1ICFA 3MHSA 4OELA 5A24A 1PE6A 2O6XA 3RVWA 1X9YA 3CH2X 2FT2A 1PADA 2HH5A 1PBHA 1QXPA 3BCNA 3PNRA 2DJFB 4HWYA 1SP4B 2OZ2A 4YYWA 2AYOA 3P5UA 1CPJA 2ATOA 2DC6A 2NQGA 2YJBA 3WXFA 3F75A 4CDFB 3P5WA 2BDLA 2HD5A 2PBHA 1CQDA 4YYUA 2E00A 1AU2A 2YJ2A 2R9CA 2CIOA 5JA7A 1CTEA 3KSEA 2FQ9A 3PDFA 9PAPA 1A6RA 4QBBA 4YYRA 2G7YA 3WXEA 3D6SA 4X6HA 1YALA 1BGOA 4G54A 4BQVA 2JQFR 3B79A 2DC9A 1YT7A 1VJVA 4RY2A 4QRXA 5EGWA 2AU1A 3OVXA 1KXRA 4N79A 8PCHA 5CVOB 3CBKA 1TU6A 3K9MA 1PPPA 3RVVA 3E1ZB 4YYSA 5K16A 2DZZA 3KFQA 2FTDA 1NPZA 2G8JA 1BP4A 2FO5A 4Q8GA 3HHIA 3S3RA 2B1NA 2P0RA 3BPMA 1SNKA 3USVA 1MEGA 3S3QA 1POPA 4FIPA 1CB5A 3H8BA 3N3GA 2NQDB 1CVZA 2HHNA 1K3BB 4PP2E 4OEMA 2GHUA 1STFE 2DCCA 3IHPA 4PADA 2ARYA 1NB5A 1EWLA 1QOLA 5JH3A 2IPPB 2F7DA 3M99A 2HXZA 1ATKA 2DC8A 1AU0A 3RVXA 4PI3A 3LFYA 2GFOA 2Y6EA 1MIRA 2PADA 2XU4A 4WA6A 6PADA 3N3KA 1M6DA 2YJCA 3ZUAA 3WXGA 4KLBA 1U9XA 2E02A 5CHTA 2P86A 4QRVA 3TNXA 4W4UA 3H6SA 7PCKA 1EWMA 2FUDA 4MSXA 1GMYA 2NQIA 5CHVA 4AXMA 1NLJA 3V6CA 5CVMA 1Y08A 1CV8A 1KHPA 4XUIA 2XU1A 3ERVA 2AS8A 2P7UA 1KFXL 1NQCA 1CS8A 4AXLA 4I07A 1S4VA 5EF4A 3MHHA 2DCAA 3DF0A 2YJ8A 1NB3A 3MTNA 1AU4A 2OULA 2OP3A 1TLOA 2WBFX 3PW3A 1AYVA 1ITOA 1EF7A 3PBHA 2ACTA 3P5XA 1XKGA 1PCIA 4W5CA 4CDCB 2G6DA 4YYVA 2DJGB 1NL6A 1BQIA 2Y5BA 1AYUA 1U9QX 2NQAA 1CSBB 4W5BA 1DF0A 4I04A 4P6EA 2R9NA 4X6JA 1KFUL 2YJ9A 3BC3A 3H7DA 4YYQA 3V6EA 5F02A 2PNSA 2F1GA 4FK5A 2PREA 3BOWA 3IV2A 1YK7A 2C0YA 5CVNB 2B1MA 4X6IA 1JQPA 3O0UA 4CDEB 4P6GA 1F2BA 2VHSA 5PADA 3HD3A 1THEA 3H89A 1QDQA 3KWBX 3P5VA 3I06A 2FRAA 3I3TA 3U8EA 4CZWA 2VHFA 1DEUA 2FYEA 3OF8A 1U5IA 3CH3X 1IWDA 4BSQA 2AVWA 1ME3A 4QRGA 1AECA 4BS6A 2R9FA 2DCBA 1PXVA 3BPFA 3IUTA 3QSDA 1AU3A 3K8UA 1GCBA 3GCBA 2R6NA 3MORA 3QT4A 1F2CA 3C9EA 1EWOA 2XU3A 1YK8A 4DMYA 1HUCB 4QH6A 3BWKA 1ZCMA 2E03A 1Q6KA 4N4ZA 2DCDA 2BDZA 2FRQA 1TL9A 3AI8A 3IEJA 3F5VA 1PIPA 2H7JA 1GECE 1PPOA 2DC7A 3KWZA 1KHQA 1MDWA 5FPWA 2IBIA 4YVAA 1F29A 1GLOA 1VSNA 3QJ3A 2E01A 3K24A 3HHAA 2AUZA 1AYWA 1PPNA 1PPDA 2CB5A 4XR7A 4I05A 2G8EA 3KW9A 1MEMA 2R9MA 4BPVA 3N4CA 1QMYA 2AYNA 2XU5A 3OVZA 3OF9A 4PP1A 2R9OA 3LXSA 4K7CA 4DMXA 2DZYA 1U9WA 4CDDB 3IOQA 1U9VA 1MHWA 4YV8A 1ME4A 4BS5A 3OISA
chains in the Genus database with same CATH superfamily
1ZIVA 5J94A 1BY8A 3H8CA 3KX1A 2J7QA 5KO3A 4P16A 2AUXA 1CJLA 4N8WA 4IUMA 1EWPA 3W30A 3NHEA 1AIMA 3IMAA 4FJCA 4MZSA 2AIMA 3CBJA 1FH0A 3KKUA 1Y4HA 1MS6A 4REZA 3O1GA 4Q8HA 1F2AA 1YVBA 3HWNA 4MZOA 4ZUXU 1O0EA 2JQGR 1ICFA 3MHSA 4OELA 5A24A 1PE6A 2O6XA 3RVWA 1X9YA 3CH2X 4BOUA 2FT2A 1PADA 2HH5A 1PBHA 1QXPA 3BCNA 3PNRA 2DJFB 4HWYA 1SP4B 2OZ2A 4YYWA 2AYOA 3MTVA 3P5UA 3PHWA 4OVZB 1CPJA 2ATOA 2DC6A 2NQGA 2YJBA 3WXFA 3F75A 4CDFB 3P5WA 2BDLA 2HD5A 3C0RA 2PBHA 1CQDA 4YYUA 2E00A 1AU2A 2DOSA 4D8EA 2YJ2A 2R9CA 2CIOA 5JA7A 1CTEA 3KSEA 2FQ9A 3PDFA 2BTWA 9PAPA 1A6RA 4QBBA 4YYRA 4R3DA 2G7YA 3WXEA 3D6SA 4X6HA 1YALA 4M0WA 1BGOA 3PRMA 4G54A 4BQVA 2JQFR 3B79A 2DC9A 1YT7A 1VJVA 4RY2A 4QRXA 5EGWA 2AU1A 3OVXA 1KXRA 3OQCA 4N79A 8PCHA 5CVOB 1DKIA 3CBKA 1TU6A 3K9MA 1PPPA 3RVVA 1UKFA 3E1ZB 4YYSA 5K16A 2DZZA 3KFQA 2FTDA 1NPZA 1YZBA 2G8JA 1BP4A 2FO5A 2UZJA 4PT5A 4Q8GA 3HHIA 3S3RA 2B1NA 2P0RA 3BPMA 1SNKA 2BTWB 4MM3B 3USVA 1MEGA 3S3QA 1POPA 4FIPA 1CB5A 3H8BA 3N3GA 3PT2A 2NQDB 1CVZA 2HHNA 1K3BB 4PP2E 4OEMA 2GHUA 1STFE 2DCCA 3IHPA 4PADA 2ARYA 1NB5A 1EWLA 1QOLA 4D8BA 5JH3A 2IPPB 2F7DA 4MI7A 3M99A 2HXZA 3W31A 1ATKA 2DC8A 1AU0A 3RVXA 4PI3A 3BY4A 3LFYA 2GFOA 5EZSA 2Y6EA 4BOPA 1MIRA 2PADA 2XU4A 4WA6A 6PADA 1PVJA 2HWKA 2AGAA 3N3KA 1M6DA 2YJCA 3ZUAA 3WXGA 4KLBA 1U9XA 2E02A 5CHTA 2P86A 2JRIA 4QRVA 3TNXA 4HXDB 4W4UA 3H6SA 4BOZA 7PCKA 1EWMA 2FUDA 4MSXA 1GMYA 4RF0A 2NQIA 5CHVA 3PHXA 4AXMA 1NLJA 3V6CA 5CVMA 1Y08A 1CV8A 1KHPA 4XUIA 2XU1A 3ERVA 2AS8A 2P7UA 1KFXL 1NQCA 1CS8A 4AXLA 4I07A 1S4VA 5EF4A 3MHHA 2DCAA 3DF0A 2YJ8A 1NB3A 3MTNA 1AU4A 3E9SA 2OULA 2OP3A 1TLOA 2WBFX 5EZQA 3PW3A 2BU3A 4ZTBA 1AYVA 1ITOA 1EF7A 3PBHA 2ACTA 3P5XA 1XKGA 1PCIA 2JTCA 4GUAA 3PSEA 4W5CA 4CDCB 2G6DA 4YYVA 2DJGB 1NL6A 1BQIA 2Y5BA 1AYUA 1U9QX 2NQAA 5E6JA 4IP3A 1CSBB 4W5BA 1DF0A 3TMPA 4I04A 4P6EA 2R9NA 4X6JA 1KFUL 4BOSA 2YJ9A 3BC3A 3H7DA 4YYQA 3V6EA 2J7QC 5F02A 2PNSA 2F1GA 4FK5A 2PREA 3BOWA 3IV2A 3IFUA 1YK7A 2C0YA 5CVNB 3PHUA 2B1MA 4X6IA 3RNVA 1JQPA 3O0UA 4CDEB 4P6GA 1F2BA 2VHSA 4D8IA 5PADA 3HD3A 1THEA 3H89A 1QDQA 4RKXA 3KWBX 3P5VA 3I06A 2FRAA 3I3TA 3U8EA 4CZWA 4OW0A 2VHFA 1DEUA 2FYEA 3OF8A 1U5IA 3CH3X 1IWDA 4XZXA 4BSQA 2AVWA 1ME3A 4QRGA 1AECA 4BS6A 5JZEA 2R9FA 2DCBA 1PXVA 3BPFA 3IUTA 3QSDA 2Z84A 1AU3A 3K8UA 1GCBA 3GCBA 2R6NA 3MORA 3QT4A 1F2CA 3C9EA 4RF1A 1EWOA 2XU3A 4RNAA 1YK8A 3BB7A 4DMYA 4BOQA 1HUCB 4QH6A 3BWKA 3PRPA 1ZCMA 2E03A 1Q6KA 4N4ZA 2DCDA 2BDZA 3ZNHA 2FRQA 1TL9A 3MP2A 3AI8A 3IEJA 3F5VA 1PIPA 2H7JA 1GECE 1PPOA 2DC7A 3KWZA 1KHQA 1MDWA 5FPWA 4A5UA 2IBIA 4YVAA 1F29A 1GLOA 1VSNA 3O65A 3QJ3A 2E01A 3K24A 3HHAA 4WURA 2AUZA 1AYWA 1PPNA 1PPDA 2CB5A 4XR7A 4I05A 2G8EA 3KW9A 3BBAA 1MEMA 2R9MA 4BPVA 3N4CA 3TRKA 1QMYA 2AYNA 2XU5A 3OVZA 3MJ5A 3B21A 3OF9A 4PP1A 2R9OA 3LXSA 4K7CA 4DMXA 2DZYA 1U9WA 4CDDB 3IOQA 2FE8A 1U9VA 1MHWA 4YV8A 1ME4A 4BS5A 4OVZA 3OISA
chains in the Genus database with same CATH topology
1ZIVA 5J94A 1BY8A 3H8CA 3KX1A 2AUXA 1CJLA 4N8WA 1EWPA 3NHEA 1AIMA 3IMAA 4FJCA 4MZSA 2AIMA 3CBJA 1FH0A 3KKUA 1Y4HA 1MS6A 3O1GA 4Q8HA 1F2AA 1YVBA 3HWNA 3D9WA 4MZOA 4ZUXU 1O0EA 2JQGR 1ICFA 3MHSA 4OELA 5A24A 1PE6A 2O6XA 3RVWA 4NV8A 1X9YA 3CH2X 2FT2A 1PADA 2HH5A 1PBHA 1QXPA 3BCNA 3PNRA 2DJFB 4HWYA 1SP4B 2OZ2A 4YYWA 2AYOA 3P5UA 1CPJA 2ATOA 2DC6A 2NQGA 2YJBA 3WXFA 3F75A 4CDFB 3P5WA 2BDLA 2HD5A 4B55A 2PBHA 1CQDA 4YYUA 2E00A 1AU2A 2YJ2A 2R9CA 2CIOA 5JA7A 1CTEA 3KSEA 2FQ9A 3PDFA 9PAPA 1A6RA 4QBBA 4YYRA 2G7YA 3WXEA 3D6SA 4X6HA 1YALA 1BGOA 1W5RA 4G54A 4BQVA 2JQFR 3B79A 2DC9A 1YT7A 1VJVA 4RY2A 4C5PA 4QRXA 5EGWA 2AU1A 3OVXA 1KXRA 2VFBA 4N79A 8PCHA 5CVOB 3CBKA 1TU6A 3K9MA 1PPPA 3RVVA 3E1ZB 4YYSA 5K16A 2DZZA 3KFQA 2FTDA 1NPZA 2G8JA 1BP4A 2FO5A 4Q8GA 3HHIA 3S3RA 2B1NA 2P0RA 3BPMA 1SNKA 3USVA 1MEGA 3S3QA 1POPA 4FIPA 1CB5A 3H8BA 3N3GA 2NQDB 1CVZA 2HHNA 1K3BB 4PP2E 4OEMA 2GHUA 1STFE 2DCCA 3IHPA 4PADA 2ARYA 1NB5A 1EWLA 1QOLA 5JH3A 2IPPB 2F7DA 3M99A 1W6FA 2HXZA 1ATKA 2DC8A 1AU0A 3RVXA 4PI3A 3LFYA 2GFOA 2Y6EA 1MIRA 2PADA 2XU4A 4WA6A 6PADA 3N3KA 1M6DA 2YJCA 3ZUAA 3WXGA 4KLBA 1U9XA 2E02A 5CHTA 2P86A 4QRVA 3TNXA 4W4UA 3H6SA 7PCKA 2VFCA 1EWMA 2FUDA 4MSXA 1GMYA 2NQIA 5CHVA 4AXMA 1NLJA 3V6CA 5CVMA 1Y08A 1CV8A 1KHPA 4XUIA 2XU1A 3ERVA 2AS8A 2P7UA 1KFXL 1NQCA 1CS8A 4AXLA 4I07A 1S4VA 5EF4A 3MHHA 2DCAA 3DF0A 2YJ8A 1NB3A 3MTNA 1AU4A 2OULA 2OP3A 1TLOA 3LTWA 2WBFX 3PW3A 1AYVA 1ITOA 1EF7A 3PBHA 2ACTA 3P5XA 1XKGA 1PCIA 4W5CA 4CDCB 2G6DA 4YYVA 2DJGB 1NL6A 1BQIA 2Y5BA 1AYUA 1U9QX 2NQAA 1CSBB 4W5BA 1DF0A 4I04A 4P6EA 2R9NA 4X6JA 1KFUL 2YJ9A 3BC3A 3H7DA 4YYQA 3V6EA 5F02A 2PNSA 2F1GA 4FK5A 2PREA 3BOWA 3IV2A 1YK7A 2C0YA 5CVNB 2B1MA 4X6IA 1JQPA 3O0UA 4CDEB 4P6GA 1F2BA 2VHSA 5PADA 3HD3A 4BGFA 1THEA 3H89A 1QDQA 3KWBX 3P5VA 3I06A 2FRAA 3I3TA 3U8EA 4CZWA 2VHFA 1DEUA 2FYEA 3OF8A 1U5IA 3CH3X 1IWDA 4BSQA 2AVWA 1ME3A 4QRGA 1AECA 4BS6A 2R9FA 2DCBA 1PXVA 3BPFA 3IUTA 3QSDA 1AU3A 3K8UA 1GCBA 3GCBA 2R6NA 3MORA 3QT4A 1F2CA 3C9EA 1EWOA 1E2TA 2XU3A 1YK8A 4DMYA 1HUCB 4QH6A 3BWKA 1W4TA 1ZCMA 2E03A 1Q6KA 4N4ZA 2DCDA 2BDZA 2FRQA 1TL9A 3AI8A 3IEJA 3F5VA 1PIPA 2H7JA 1GECE 1PPOA 2DC7A 3KWZA 1KHQA 1MDWA 5FPWA 2IBIA 2BSZA 4YVAA 1F29A 1GLOA 1VSNA 3QJ3A 2E01A 3K24A 3HHAA 2AUZA 1AYWA 1PPNA 1PPDA 2CB5A 4XR7A 4I05A 2G8EA 3KW9A 1MEMA 2R9MA 4BPVA 3N4CA 1GX3A 1QMYA 2AYNA 2XU5A 3OVZA 3OF9A 4PP1A 2R9OA 3LXSA 4K7CA 4DMXA 2DZYA 1U9WA 4CDDB 3IOQA 1U9VA 1MHWA 4YV8A 1ME4A 4BS5A 4NV7A 4GUZA 3OISA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZIV A;  5J94 A;  1BY8 A;  3H8C A;  3KX1 A;  2AUX A;  1CJL A;  4N8W A;  1EWP A;  3NHE A;  1AIM A;  3IMA A;  4FJC A;  4MZS A;  2AIM A;  3CBJ A;  1FH0 A;  3KKU A;  1Y4H A;  1MS6 A;  3O1G A;  4Q8H A;  1F2A A;  1YVB A;  3HWN A;  4MZO A;  4ZUX U;  1O0E A;  2JQG R;  1ICF A;  3MHS A;  4OEL A;  5A24 A;  1PE6 A;  2O6X A;  3RVW A;  1X9Y A;  3CH2 X;  2FT2 A;  1PAD A;  2HH5 A;  1PBH A;  1QXP A;  3BCN A;  3PNR A;  2DJF B;  4HWY A;  1SP4 B;  2OZ2 A;  4YYW A;  2AYO A;  3P5U A;  1CPJ A;  2ATO A;  2DC6 A;  2NQG A;  2YJB A;  3WXF A;  3F75 A;  4CDF B;  3P5W A;  2BDL A;  2HD5 A;  2PBH A;  1CQD A;  4YYU A;  2E00 A;  1AU2 A;  2YJ2 A;  2R9C A;  2CIO A;  5JA7 A;  1CTE A;  3KSE A;  2FQ9 A;  3PDF A;  9PAP A;  1A6R A;  4QBB A;  4YYR A;  2G7Y A;  3WXE A;  3D6S A;  4X6H A;  1YAL A;  1BGO A;  4G54 A;  4BQV A;  2JQF R;  3B79 A;  2DC9 A;  1YT7 A;  1VJV A;  4RY2 A;  4QRX A;  5EGW A;  2AU1 A;  3OVX A;  1KXR A;  4N79 A;  8PCH A;  5CVO B;  3CBK A;  1TU6 A;  3K9M A;  1PPP A;  3RVV A;  3E1Z B;  4YYS A;  5K16 A;  2DZZ A;  3KFQ A;  2FTD A;  1NPZ A;  2G8J A;  1BP4 A;  2FO5 A;  4Q8G A;  3HHI A;  3S3R A;  2B1N A;  2P0R A;  3BPM A;  1SNK A;  3USV A;  1MEG A;  3S3Q A;  1POP A;  4FIP A;  1CB5 A;  3H8B A;  3N3G A;  2NQD B;  1CVZ A;  2HHN A;  1K3B B;  4PP2 E;  4OEM A;  2GHU A;  1STF E;  2DCC A;  3IHP A;  4PAD A;  2ARY A;  1NB5 A;  1EWL A;  1QOL A;  5JH3 A;  2IPP B;  2F7D A;  3M99 A;  2HXZ A;  1ATK A;  2DC8 A;  1AU0 A;  3RVX A;  4PI3 A;  3LFY A;  2GFO A;  2Y6E A;  1MIR A;  2PAD A;  2XU4 A;  4WA6 A;  6PAD A;  3N3K A;  1M6D A;  2YJC A;  3ZUA A;  3WXG A;  4KLB A;  1U9X A;  2E02 A;  5CHT A;  2P86 A;  4QRV A;  3TNX A;  4W4U A;  3H6S A;  7PCK A;  1EWM A;  2FUD A;  4MSX A;  1GMY A;  2NQI A;  5CHV A;  4AXM A;  1NLJ A;  3V6C A;  5CVM A;  1Y08 A;  1CV8 A;  1KHP A;  4XUI A;  2XU1 A;  3ERV A;  2AS8 A;  2P7U A;  1KFX L;  1NQC A;  1CS8 A;  4AXL A;  4I07 A;  1S4V A;  5EF4 A;  3MHH A;  2DCA A;  3DF0 A;  2YJ8 A;  1NB3 A;  3MTN A;  1AU4 A;  2OUL A;  2OP3 A;  1TLO A;  2WBF X;  3PW3 A;  1AYV A;  1ITO A;  1EF7 A;  3PBH A;  2ACT A;  3P5X A;  1XKG A;  1PCI A;  4W5C A;  4CDC B;  2G6D A;  4YYV A;  2DJG B;  1NL6 A;  1BQI A;  2Y5B A;  1AYU A;  1U9Q X;  2NQA A;  1CSB B;  4W5B A;  1DF0 A;  4I04 A;  4P6E A;  2R9N A;  4X6J A;  1KFU L;  2YJ9 A;  3BC3 A;  3H7D A;  4YYQ A;  3V6E A;  5F02 A;  2PNS A;  2F1G A;  4FK5 A;  2PRE A;  3BOW A;  3IV2 A;  1YK7 A;  2C0Y A;  5CVN B;  2B1M A;  4X6I A;  1JQP A;  3O0U A;  4CDE B;  4P6G A;  1F2B A;  2VHS A;  5PAD A;  3HD3 A;  1THE A;  3H89 A;  1QDQ A;  3KWB X;  3P5V A;  3I06 A;  2FRA A;  3I3T A;  3U8E A;  4CZW A;  2VHF A;  1DEU A;  2FYE A;  3OF8 A;  1U5I A;  3CH3 X;  1IWD A;  4BSQ A;  2AVW A;  1ME3 A;  4QRG A;  1AEC A;  4BS6 A;  2R9F A;  2DCB A;  1PXV A;  3BPF A;  3IUT A;  3QSD A;  1AU3 A;  3K8U A;  1GCB A;  3GCB A;  2R6N A;  3MOR A;  3QT4 A;  1F2C A;  3C9E A;  1EWO A;  2XU3 A;  1YK8 A;  4DMY A;  1HUC B;  4QH6 A;  3BWK A;  1ZCM A;  2E03 A;  1Q6K A;  4N4Z A;  2DCD A;  2BDZ A;  2FRQ A;  1TL9 A;  3AI8 A;  3IEJ A;  3F5V A;  1PIP A;  2H7J A;  1GEC E;  1PPO A;  2DC7 A;  3KWZ A;  1KHQ A;  1MDW A;  5FPW A;  2IBI A;  4YVA A;  1F29 A;  1GLO A;  1VSN A;  3QJ3 A;  2E01 A;  3K24 A;  3HHA A;  2AUZ A;  1AYW A;  1PPN A;  1PPD A;  2CB5 A;  4XR7 A;  4I05 A;  2G8E A;  3KW9 A;  1MEM A;  2R9M A;  4BPV A;  3N4C A;  1QMY A;  2AYN A;  2XU5 A;  3OVZ A;  3OF9 A;  4PP1 A;  2R9O A;  3LXS A;  4K7C A;  4DMX A;  2DZY A;  1U9W A;  4CDD B;  3IOQ A;  1U9V A;  1MHW A;  4YV8 A;  1ME4 A;  4BS5 A;  3OIS A; 
#chains in the Genus database with same CATH topology
 1ZIV A;  5J94 A;  1BY8 A;  3H8C A;  3KX1 A;  2J7Q A;  5KO3 A;  4P16 A;  2AUX A;  1CJL A;  4N8W A;  4IUM A;  1EWP A;  3W30 A;  3NHE A;  1AIM A;  3IMA A;  4FJC A;  4MZS A;  2AIM A;  3CBJ A;  1FH0 A;  3KKU A;  1Y4H A;  1MS6 A;  4REZ A;  3O1G A;  4Q8H A;  1F2A A;  1YVB A;  3HWN A;  4MZO A;  4ZUX U;  1O0E A;  2JQG R;  1ICF A;  3MHS A;  4OEL A;  5A24 A;  1PE6 A;  2O6X A;  3RVW A;  1X9Y A;  3CH2 X;  4BOU A;  2FT2 A;  1PAD A;  2HH5 A;  1PBH A;  1QXP A;  3BCN A;  3PNR A;  2DJF B;  4HWY A;  1SP4 B;  2OZ2 A;  4YYW A;  2AYO A;  3MTV A;  3P5U A;  3PHW A;  4OVZ B;  1CPJ A;  2ATO A;  2DC6 A;  2NQG A;  2YJB A;  3WXF A;  3F75 A;  4CDF B;  3P5W A;  2BDL A;  2HD5 A;  3C0R A;  2PBH A;  1CQD A;  4YYU A;  2E00 A;  1AU2 A;  2DOS A;  4D8E A;  2YJ2 A;  2R9C A;  2CIO A;  5JA7 A;  1CTE A;  3KSE A;  2FQ9 A;  3PDF A;  2BTW A;  9PAP A;  1A6R A;  4QBB A;  4YYR A;  4R3D A;  2G7Y A;  3WXE A;  3D6S A;  4X6H A;  1YAL A;  4M0W A;  1BGO A;  3PRM A;  4G54 A;  4BQV A;  2JQF R;  3B79 A;  2DC9 A;  1YT7 A;  1VJV A;  4RY2 A;  4QRX A;  5EGW A;  2AU1 A;  3OVX A;  1KXR A;  3OQC A;  4N79 A;  8PCH A;  5CVO B;  1DKI A;  3CBK A;  1TU6 A;  3K9M A;  1PPP A;  3RVV A;  1UKF A;  3E1Z B;  4YYS A;  5K16 A;  2DZZ A;  3KFQ A;  2FTD A;  1NPZ A;  1YZB A;  2G8J A;  1BP4 A;  2FO5 A;  2UZJ A;  4PT5 A;  4Q8G A;  3HHI A;  3S3R A;  2B1N A;  2P0R A;  3BPM A;  1SNK A;  2BTW B;  4MM3 B;  3USV A;  1MEG A;  3S3Q A;  1POP A;  4FIP A;  1CB5 A;  3H8B A;  3N3G A;  3PT2 A;  2NQD B;  1CVZ A;  2HHN A;  1K3B B;  4PP2 E;  4OEM A;  2GHU A;  1STF E;  2DCC A;  3IHP A;  4PAD A;  2ARY A;  1NB5 A;  1EWL A;  1QOL A;  4D8B A;  5JH3 A;  2IPP B;  2F7D A;  4MI7 A;  3M99 A;  2HXZ A;  3W31 A;  1ATK A;  2DC8 A;  1AU0 A;  3RVX A;  4PI3 A;  3BY4 A;  3LFY A;  2GFO A;  5EZS A;  2Y6E A;  4BOP A;  1MIR A;  2PAD A;  2XU4 A;  4WA6 A;  6PAD A;  1PVJ A;  2HWK A;  2AGA A;  3N3K A;  1M6D A;  2YJC A;  3ZUA A;  3WXG A;  4KLB A;  1U9X A;  2E02 A;  5CHT A;  2P86 A;  2JRI A;  4QRV A;  3TNX A;  4HXD B;  4W4U A;  3H6S A;  4BOZ A;  7PCK A;  1EWM A;  2FUD A;  4MSX A;  1GMY A;  4RF0 A;  2NQI A;  5CHV A;  3PHX A;  4AXM A;  1NLJ A;  3V6C A;  5CVM A;  1Y08 A;  1CV8 A;  1KHP A;  4XUI A;  2XU1 A;  3ERV A;  2AS8 A;  2P7U A;  1KFX L;  1NQC A;  1CS8 A;  4AXL A;  4I07 A;  1S4V A;  5EF4 A;  3MHH A;  2DCA A;  3DF0 A;  2YJ8 A;  1NB3 A;  3MTN A;  1AU4 A;  3E9S A;  2OUL A;  2OP3 A;  1TLO A;  2WBF X;  5EZQ A;  3PW3 A;  2BU3 A;  4ZTB A;  1AYV A;  1ITO A;  1EF7 A;  3PBH A;  2ACT A;  3P5X A;  1XKG A;  1PCI A;  2JTC A;  4GUA A;  3PSE A;  4W5C A;  4CDC B;  2G6D A;  4YYV A;  2DJG B;  1NL6 A;  1BQI A;  2Y5B A;  1AYU A;  1U9Q X;  2NQA A;  5E6J A;  4IP3 A;  1CSB B;  4W5B A;  1DF0 A;  3TMP A;  4I04 A;  4P6E A;  2R9N A;  4X6J A;  1KFU L;  4BOS A;  2YJ9 A;  3BC3 A;  3H7D A;  4YYQ A;  3V6E A;  2J7Q C;  5F02 A;  2PNS A;  2F1G A;  4FK5 A;  2PRE A;  3BOW A;  3IV2 A;  3IFU A;  1YK7 A;  2C0Y A;  5CVN B;  3PHU A;  2B1M A;  4X6I A;  3RNV A;  1JQP A;  3O0U A;  4CDE B;  4P6G A;  1F2B A;  2VHS A;  4D8I A;  5PAD A;  3HD3 A;  1THE A;  3H89 A;  1QDQ A;  4RKX A;  3KWB X;  3P5V A;  3I06 A;  2FRA A;  3I3T A;  3U8E A;  4CZW A;  4OW0 A;  2VHF A;  1DEU A;  2FYE A;  3OF8 A;  1U5I A;  3CH3 X;  1IWD A;  4XZX A;  4BSQ A;  2AVW A;  1ME3 A;  4QRG A;  1AEC A;  4BS6 A;  5JZE A;  2R9F A;  2DCB A;  1PXV A;  3BPF A;  3IUT A;  3QSD A;  2Z84 A;  1AU3 A;  3K8U A;  1GCB A;  3GCB A;  2R6N A;  3MOR A;  3QT4 A;  1F2C A;  3C9E A;  4RF1 A;  1EWO A;  2XU3 A;  4RNA A;  1YK8 A;  3BB7 A;  4DMY A;  4BOQ A;  1HUC B;  4QH6 A;  3BWK A;  3PRP A;  1ZCM A;  2E03 A;  1Q6K A;  4N4Z A;  2DCD A;  2BDZ A;  3ZNH A;  2FRQ A;  1TL9 A;  3MP2 A;  3AI8 A;  3IEJ A;  3F5V A;  1PIP A;  2H7J A;  1GEC E;  1PPO A;  2DC7 A;  3KWZ A;  1KHQ A;  1MDW A;  5FPW A;  4A5U A;  2IBI A;  4YVA A;  1F29 A;  1GLO A;  1VSN A;  3O65 A;  3QJ3 A;  2E01 A;  3K24 A;  3HHA A;  4WUR A;  2AUZ A;  1AYW A;  1PPN A;  1PPD A;  2CB5 A;  4XR7 A;  4I05 A;  2G8E A;  3KW9 A;  3BBA A;  1MEM A;  2R9M A;  4BPV A;  3N4C A;  3TRK A;  1QMY A;  2AYN A;  2XU5 A;  3OVZ A;  3MJ5 A;  3B21 A;  3OF9 A;  4PP1 A;  2R9O A;  3LXS A;  4K7C A;  4DMX A;  2DZY A;  1U9W A;  4CDD B;  3IOQ A;  2FE8 A;  1U9V A;  1MHW A;  4YV8 A;  1ME4 A;  4BS5 A;  4OVZ A;  3OIS A; 
#chains in the Genus database with same CATH homology
 1ZIV A;  5J94 A;  1BY8 A;  3H8C A;  3KX1 A;  2AUX A;  1CJL A;  4N8W A;  1EWP A;  3NHE A;  1AIM A;  3IMA A;  4FJC A;  4MZS A;  2AIM A;  3CBJ A;  1FH0 A;  3KKU A;  1Y4H A;  1MS6 A;  3O1G A;  4Q8H A;  1F2A A;  1YVB A;  3HWN A;  3D9W A;  4MZO A;  4ZUX U;  1O0E A;  2JQG R;  1ICF A;  3MHS A;  4OEL A;  5A24 A;  1PE6 A;  2O6X A;  3RVW A;  4NV8 A;  1X9Y A;  3CH2 X;  2FT2 A;  1PAD A;  2HH5 A;  1PBH A;  1QXP A;  3BCN A;  3PNR A;  2DJF B;  4HWY A;  1SP4 B;  2OZ2 A;  4YYW A;  2AYO A;  3P5U A;  1CPJ A;  2ATO A;  2DC6 A;  2NQG A;  2YJB A;  3WXF A;  3F75 A;  4CDF B;  3P5W A;  2BDL A;  2HD5 A;  4B55 A;  2PBH A;  1CQD A;  4YYU A;  2E00 A;  1AU2 A;  2YJ2 A;  2R9C A;  2CIO A;  5JA7 A;  1CTE A;  3KSE A;  2FQ9 A;  3PDF A;  9PAP A;  1A6R A;  4QBB A;  4YYR A;  2G7Y A;  3WXE A;  3D6S A;  4X6H A;  1YAL A;  1BGO A;  1W5R A;  4G54 A;  4BQV A;  2JQF R;  3B79 A;  2DC9 A;  1YT7 A;  1VJV A;  4RY2 A;  4C5P A;  4QRX A;  5EGW A;  2AU1 A;  3OVX A;  1KXR A;  2VFB A;  4N79 A;  8PCH A;  5CVO B;  3CBK A;  1TU6 A;  3K9M A;  1PPP A;  3RVV A;  3E1Z B;  4YYS A;  5K16 A;  2DZZ A;  3KFQ A;  2FTD A;  1NPZ A;  2G8J A;  1BP4 A;  2FO5 A;  4Q8G A;  3HHI A;  3S3R A;  2B1N A;  2P0R A;  3BPM A;  1SNK A;  3USV A;  1MEG A;  3S3Q A;  1POP A;  4FIP A;  1CB5 A;  3H8B A;  3N3G A;  2NQD B;  1CVZ A;  2HHN A;  1K3B B;  4PP2 E;  4OEM A;  2GHU A;  1STF E;  2DCC A;  3IHP A;  4PAD A;  2ARY A;  1NB5 A;  1EWL A;  1QOL A;  5JH3 A;  2IPP B;  2F7D A;  3M99 A;  1W6F A;  2HXZ A;  1ATK A;  2DC8 A;  1AU0 A;  3RVX A;  4PI3 A;  3LFY A;  2GFO A;  2Y6E A;  1MIR A;  2PAD A;  2XU4 A;  4WA6 A;  6PAD A;  3N3K A;  1M6D A;  2YJC A;  3ZUA A;  3WXG A;  4KLB A;  1U9X A;  2E02 A;  5CHT A;  2P86 A;  4QRV A;  3TNX A;  4W4U A;  3H6S A;  7PCK A;  2VFC A;  1EWM A;  2FUD A;  4MSX A;  1GMY A;  2NQI A;  5CHV A;  4AXM A;  1NLJ A;  3V6C A;  5CVM A;  1Y08 A;  1CV8 A;  1KHP A;  4XUI A;  2XU1 A;  3ERV A;  2AS8 A;  2P7U A;  1KFX L;  1NQC A;  1CS8 A;  4AXL A;  4I07 A;  1S4V A;  5EF4 A;  3MHH A;  2DCA A;  3DF0 A;  2YJ8 A;  1NB3 A;  3MTN A;  1AU4 A;  2OUL A;  2OP3 A;  1TLO A;  3LTW A;  2WBF X;  3PW3 A;  1AYV A;  1ITO A;  1EF7 A;  3PBH A;  2ACT A;  3P5X A;  1XKG A;  1PCI A;  4W5C A;  4CDC B;  2G6D A;  4YYV A;  2DJG B;  1NL6 A;  1BQI A;  2Y5B A;  1AYU A;  1U9Q X;  2NQA A;  1CSB B;  4W5B A;  1DF0 A;  4I04 A;  4P6E A;  2R9N A;  4X6J A;  1KFU L;  2YJ9 A;  3BC3 A;  3H7D A;  4YYQ A;  3V6E A;  5F02 A;  2PNS A;  2F1G A;  4FK5 A;  2PRE A;  3BOW A;  3IV2 A;  1YK7 A;  2C0Y A;  5CVN B;  2B1M A;  4X6I A;  1JQP A;  3O0U A;  4CDE B;  4P6G A;  1F2B A;  2VHS A;  5PAD A;  3HD3 A;  4BGF A;  1THE A;  3H89 A;  1QDQ A;  3KWB X;  3P5V A;  3I06 A;  2FRA A;  3I3T A;  3U8E A;  4CZW A;  2VHF A;  1DEU A;  2FYE A;  3OF8 A;  1U5I A;  3CH3 X;  1IWD A;  4BSQ A;  2AVW A;  1ME3 A;  4QRG A;  1AEC A;  4BS6 A;  2R9F A;  2DCB A;  1PXV A;  3BPF A;  3IUT A;  3QSD A;  1AU3 A;  3K8U A;  1GCB A;  3GCB A;  2R6N A;  3MOR A;  3QT4 A;  1F2C A;  3C9E A;  1EWO A;  1E2T A;  2XU3 A;  1YK8 A;  4DMY A;  1HUC B;  4QH6 A;  3BWK A;  1W4T A;  1ZCM A;  2E03 A;  1Q6K A;  4N4Z A;  2DCD A;  2BDZ A;  2FRQ A;  1TL9 A;  3AI8 A;  3IEJ A;  3F5V A;  1PIP A;  2H7J A;  1GEC E;  1PPO A;  2DC7 A;  3KWZ A;  1KHQ A;  1MDW A;  5FPW A;  2IBI A;  2BSZ A;  4YVA A;  1F29 A;  1GLO A;  1VSN A;  3QJ3 A;  2E01 A;  3K24 A;  3HHA A;  2AUZ A;  1AYW A;  1PPN A;  1PPD A;  2CB5 A;  4XR7 A;  4I05 A;  2G8E A;  3KW9 A;  1MEM A;  2R9M A;  4BPV A;  3N4C A;  1GX3 A;  1QMY A;  2AYN A;  2XU5 A;  3OVZ A;  3OF9 A;  4PP1 A;  2R9O A;  3LXS A;  4K7C A;  4DMX A;  2DZY A;  1U9W A;  4CDD B;  3IOQ A;  1U9V A;  1MHW A;  4YV8 A;  1ME4 A;  4BS5 A;  4NV7 A;  4GUZ A;  3OIS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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