3BPMA

Crystal structure of falcipain-3 with its inhibitor, leupeptin
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
243
structure length
243
Chain Sequence
YEANYEDVIKKYKPADAKLDRIAYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVKNNGCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIPDDKFKEALRYLGPISISIAASDDFAFYRGGFYDGECGAAPNHAVILVGYGMKDIYNEDTGRMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of falcipain-2 and falcipain-3 bound to small molecule inhibitors: implications for substrate specificity.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Cysteine protease falcipain-3
total genus 75
structure length 243
sequence length 243
chains with identical sequence B
ec nomenclature ec 3.4.22.-:
pdb deposition date 2007-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3bpmA00
1ZIVA 2OP3A 2XU4A 1QDQA 1YK7A 3BPFA 1KFUL 1MHWA 3PNRA 2B1NA 3CH2X 3V6CA 4FK5A 1U5IA 7PCKA 1CQDA 3P5XA 4CDEB 2E00A 1STFE 4QH6A 2G6DA 3K24A 2GHUA 4CDCB 1CJLA 4P6GA 1JQPA 3RVXA 1Q6KA 1AYWA 4X6IA 4PP1A 2E02A 4YYSA 1F2CA 2YJCA 1NB3A 2WBFX 3BPMA 1PIPA 2IBIA 1PPNA 1O0EA 2E03A 3PW3A 2R9OA 2AYNA 5EF4A 1HUCB 3K8UA 1NLJA 3P5WA 2BDLA 4PADA 1EWOA 1TU6A 2YJBA 1CB5A 1M6DA 2HH5A 4OEMA 2P0RA 5F02A 4I05A 2CB5A 1DF0A 4FIPA 1ME3A 3NHEA 1F2AA 4XUIA 4YYQA 2DCBA 4DMXA 4YYVA 4W4UA 4HWYA 4CDFB 3HD3A 2H7JA 4QBBA 3LXSA 4Q8GA 3QSDA 1NL6A 2DCDA 4K7CA 1VSNA 3RVVA 4OELA 2G8JA 1EWPA 2JQFR 4WA6A 2AIMA 3IHPA 4X6HA 3AI8A 2DZZA 1POPA 4BQVA 3MHHA 1AECA 4BPVA 3V6EA 4BSQA 2PNSA 3N4CA 4AXMA 4BS5A 3HWNA 3KWZA 1F29A 1PPOA 1GCBA 2PADA 4ZUXU 1U9QX 3CH3X 1KHPA 1AU2A 1PCIA 5FPWA 3KW9A 3IUTA 4MZSA 2CIOA 3O0UA 1NQCA 3IOQA 5CVOB 2G7YA 3BCNA 2DCAA 1AU0A 3K9MA 1S4VA 1ATKA 1NB5A 3IMAA 1CPJA 3U8EA 2AS8A 1KHQA 2OZ2A 2PREA 3LFYA 1NPZA 2AUZA 2VHSA 4XR7A 1F2BA 4N79A 5PADA 1MIRA 2NQGA 4N8WA 3MTNA 2DCCA 2DC9A 2XU1A 3BC3A 4W5CA 2P86A 2IPPB 9PAPA 2AU1A 4CDDB 5CHTA 1THEA 1ZCMA 2R9CA 1TL9A 1PPPA 3HHAA 3HHIA 1AYVA 1FH0A 3H89A 4DMYA 2Y6EA 1ME4A 2HD5A 1AYUA 2AVWA 1PE6A 3WXFA 1CTEA 2FTDA 2FRAA 3I3TA 3P5UA 1YALA 1CSBB 4I07A 1GMYA 3KFQA 3KWBX 4RY2A 3QJ3A 3H6SA 2VHFA 1QOLA 2FYEA 3RVWA 1U9XA 1AU4A 4FJCA 1QXPA 4MSXA 3KSEA 3KKUA 3S3RA 1ICFA 4AXLA 5JA7A 4PP2E 1PXVA 2NQAA 4BS6A 2AUXA 2F7DA 1K3BB 2OULA 4YVAA 3F75A 3N3GA 2PBHA 2Y5BA 2ACTA 2R6NA 1GLOA 4G54A 4Q8HA 1ITOA 1MEGA 4I04A 2FT2A 1SNKA 1YK8A 1CVZA 1CS8A 1SP4B 1BY8A 1PPDA 2FQ9A 3ERVA 3GCBA 2BDZA 4YYRA 4QRXA 2DJGB 2FUDA 2GFOA 3WXEA 1MS6A 5CHVA 3F5VA 1BGOA 1A6RA 2XU5A 3MHSA 2DJFB 1MEMA 3H8BA 1EWLA 1DEUA 2YJ9A 3CBKA 1QMYA 1PADA 1GECE 4X6JA 2NQDB 6PADA 5J94A 3M99A 2HHNA 1BP4A 2NQIA 3WXGA 3C9EA 2R9NA 3QT4A 1PBHA 1Y08A 2R9MA 4PI3A 3BOWA 2B1MA 3DF0A 3S3QA 5CVMA 3E1ZB 1CV8A 3I06A 2G8EA 2C0YA 3OVXA 1XKGA 1VJVA 4MZOA 4YYWA 3BWKA 4YV8A 1KXRA 3H8CA 4CZWA 1YVBA 1U9WA 4P6EA 3N3KA 3OF9A 3P5VA 2HXZA 3PBHA 4N4ZA 1AIMA 2R9FA 1U9VA 3MORA 1YT7A 2O6XA 3USVA 3ZUAA 2DC8A 2FO5A 1EF7A 1IWDA 2JQGR 3O1GA 4YYUA 2ATOA 3PDFA 2F1GA 1X9YA 2YJ2A 4W5BA 3TNXA 1AU3A 3B79A 5EGWA 3IEJA 3OF8A 2FRQA 5JH3A 1EWMA 2DC7A 2ARYA 2DZYA 3D6SA 2XU3A 2DC6A 1KFXL 4KLBA 2E01A 5CVNB 4QRVA 1Y4HA 3OVZA 5K16A 2AYOA 3IV2A 2P7UA 1TLOA 4QRGA 8PCHA 5A24A 3CBJA 3OISA 2YJ8A 1MDWA 3H7DA 1BQIA 3KX1A
chains in the Genus database with same CATH superfamily
1ZIVA 2OP3A 2XU4A 5EZSA 1QDQA 1YK7A 3BPFA 1KFUL 1MHWA 3PNRA 2B1NA 3CH2X 3V6CA 4FK5A 1U5IA 7PCKA 1CQDA 3P5XA 4CDEB 2E00A 1STFE 2G6DA 3K24A 4QH6A 2GHUA 4IP3A 4CDCB 1CJLA 4P6GA 1JQPA 3RVXA 1Q6KA 1AYWA 4X6IA 2FE8A 4PP1A 2E02A 4YYSA 1F2CA 2YJCA 1NB3A 2WBFX 3BPMA 1PIPA 2IBIA 4BOSA 1PPNA 1O0EA 2E03A 3PW3A 2R9OA 2AYNA 5EF4A 1HUCB 3PT2A 3K8UA 1NLJA 3P5WA 2BDLA 4HXDB 4PADA 4A5UA 3PSEA 1EWOA 1TU6A 2YJBA 1CB5A 1M6DA 2HH5A 4OEMA 2P0RA 5F02A 4I05A 2CB5A 1DF0A 4FIPA 4OW0A 1ME3A 3NHEA 1F2AA 4XUIA 4YYQA 2DCBA 4DMXA 4YYVA 4W4UA 2J7QC 4HWYA 4CDFB 3HD3A 2H7JA 4QBBA 3LXSA 4Q8GA 3QSDA 1NL6A 2DCDA 3MTVA 4K7CA 2AGAA 1VSNA 3RVVA 4OELA 2G8JA 1EWPA 2JQFR 4REZA 4WA6A 2AIMA 3IHPA 4X6HA 3AI8A 2DZZA 1POPA 4BQVA 3MHHA 1AECA 4BPVA 3V6EA 4BSQA 2PNSA 3N4CA 4AXMA 4BS5A 3HWNA 3KWZA 1UKFA 4GUAA 1F29A 1PPOA 1GCBA 2PADA 4ZUXU 3PHWA 1U9QX 3CH3X 1KHPA 1AU2A 1PCIA 2DOSA 5FPWA 1DKIA 3IUTA 3KW9A 4MZSA 5JZEA 2CIOA 3O0UA 3RNVA 1NQCA 3IOQA 5CVOB 4OVZB 4RKXA 2G7YA 3BCNA 2DCAA 3C0RA 1AU0A 3K9MA 1S4VA 1ATKA 3TMPA 4D8IA 1NB5A 4BOQA 3IMAA 1CPJA 3W30A 3U8EA 2AS8A 1KHQA 2OZ2A 2PREA 3LFYA 1NPZA 2JTCA 2AUZA 2VHSA 4XR7A 1F2BA 4N79A 2BTWB 3OQCA 5PADA 1MIRA 2NQGA 4N8WA 4M0WA 3MTNA 2DCCA 2DC9A 2XU1A 3BC3A 3PHXA 4W5CA 2P86A 4RF0A 2IPPB 9PAPA 2AU1A 4CDDB 5CHTA 1THEA 1ZCMA 2R9CA 1TL9A 1PPPA 3HHAA 3HHIA 1AYVA 1FH0A 3H89A 4DMYA 2Y6EA 1ME4A 2HD5A 1AYUA 4D8EA 2AVWA 1PE6A 4BOZA 4MI7A 3WXFA 1CTEA 2FTDA 3IFUA 2FRAA 3I3TA 3P5UA 1YALA 1CSBB 3MJ5A 4I07A 1GMYA 3KFQA 3KWBX 4RY2A 3QJ3A 3H6SA 2VHFA 1QOLA 2FYEA 3RVWA 4MM3B 1U9XA 1AU4A 4FJCA 1QXPA 3B21A 3KSEA 4MSXA 2JRIA 3KKUA 3BBAA 3S3RA 1ICFA 4AXLA 5JA7A 4PP2E 1PXVA 2NQAA 4BS6A 2AUXA 2J7QA 1PVJA 2F7DA 3TRKA 1K3BB 2OULA 4YVAA 3F75A 3N3GA 2PBHA 2Y5BA 2ACTA 2R6NA 1GLOA 4G54A 4Q8HA 1ITOA 1MEGA 4I04A 2FT2A 1SNKA 1YK8A 1CVZA 2Z84A 1CS8A 1SP4B 1BY8A 1PPDA 4D8BA 3MP2A 2FQ9A 3ERVA 3GCBA 2BDZA 4YYRA 4QRXA 2DJGB 2FUDA 3PHUA 2GFOA 3WXEA 1MS6A 2BU3A 3O65A 5CHVA 5KO3A 3F5VA 1BGOA 1A6RA 2XU5A 3MHSA 4WURA 2DJFB 1MEMA 3H8BA 1EWLA 1DEUA 2YJ9A 3CBKA 1QMYA 1PADA 1GECE 4X6JA 2NQDB 6PADA 5J94A 3M99A 2HHNA 1BP4A 2NQIA 3PRPA 3WXGA 3C9EA 3W31A 2R9NA 3QT4A 1PBHA 1Y08A 2R9MA 4PI3A 3BOWA 2B1MA 3DF0A 3S3QA 5CVMA 3E1ZB 1CV8A 3I06A 2G8EA 2C0YA 3OVXA 1XKGA 4OVZA 1VJVA 4MZOA 3ZNHA 4IUMA 4BOUA 4YYWA 3BWKA 4YV8A 1KXRA 3H8CA 4CZWA 1YVBA 1U9WA 4P6EA 3N3KA 3OF9A 3P5VA 2HXZA 3E9SA 3PBHA 4BOPA 4RF1A 4N4ZA 1AIMA 2R9FA 3BY4A 1U9VA 3MORA 1YT7A 2O6XA 3USVA 2BTWA 2UZJA 4XZXA 4ZTBA 3ZUAA 2DC8A 2FO5A 1EF7A 1IWDA 3PRMA 5EZQA 2JQGR 3O1GA 5E6JA 4YYUA 2ATOA 3PDFA 4PT5A 2F1GA 1X9YA 2HWKA 2YJ2A 4W5BA 3TNXA 4P16A 1AU3A 1YZBA 3B79A 5EGWA 3IEJA 3OF8A 2FRQA 5JH3A 1EWMA 2DC7A 4R3DA 2ARYA 2DZYA 3D6SA 2XU3A 2DC6A 1KFXL 4KLBA 2E01A 5CVNB 3BB7A 4QRVA 1Y4HA 3OVZA 5K16A 2AYOA 4RNAA 3IV2A 2P7UA 1TLOA 4QRGA 8PCHA 5A24A 3CBJA 3OISA 2YJ8A 1MDWA 3H7DA 1BQIA 3KX1A
chains in the Genus database with same CATH topology
1ZIVA 2OP3A 2XU4A 1QDQA 1YK7A 3BPFA 1KFUL 1MHWA 3PNRA 2B1NA 3CH2X 3V6CA 4FK5A 1U5IA 7PCKA 1CQDA 3P5XA 4CDEB 2E00A 1STFE 2G6DA 3K24A 4QH6A 2GHUA 4CDCB 1CJLA 4P6GA 1JQPA 3RVXA 1Q6KA 1AYWA 4X6IA 4PP1A 2E02A 4YYSA 1F2CA 2YJCA 1NB3A 2WBFX 3BPMA 1PIPA 2IBIA 4B55A 1PPNA 1O0EA 2E03A 3PW3A 2R9OA 2AYNA 5EF4A 1HUCB 3K8UA 1NLJA 3P5WA 2BDLA 4PADA 1EWOA 1TU6A 2YJBA 1CB5A 1M6DA 2HH5A 4OEMA 2P0RA 4C5PA 5F02A 4I05A 2CB5A 1DF0A 4FIPA 1ME3A 3NHEA 1F2AA 4XUIA 4YYQA 2DCBA 4DMXA 4YYVA 4W4UA 4HWYA 4CDFB 3HD3A 2H7JA 4QBBA 3LXSA 4Q8GA 3QSDA 1NL6A 2DCDA 4K7CA 1VSNA 3RVVA 4OELA 2G8JA 1EWPA 2JQFR 1W4TA 4WA6A 2AIMA 3IHPA 4X6HA 3AI8A 2DZZA 1POPA 4BQVA 3MHHA 1AECA 4BPVA 3V6EA 4BSQA 2PNSA 3N4CA 4AXMA 4BS5A 3HWNA 3KWZA 1F29A 1PPOA 1GCBA 2PADA 4ZUXU 1U9QX 3CH3X 1KHPA 1AU2A 1PCIA 5FPWA 3KW9A 3IUTA 4MZSA 2CIOA 3O0UA 1NQCA 3IOQA 5CVOB 2VFCA 2G7YA 3BCNA 2DCAA 1AU0A 3LTWA 3K9MA 1S4VA 1ATKA 1NB5A 3IMAA 1CPJA 3U8EA 2AS8A 1KHQA 2OZ2A 2PREA 3LFYA 1NPZA 2AUZA 2VHSA 1W5RA 4XR7A 1F2BA 4N79A 5PADA 1MIRA 2NQGA 4N8WA 3MTNA 2DCCA 2DC9A 1GX3A 2XU1A 3BC3A 4W5CA 2P86A 2IPPB 9PAPA 2AU1A 4CDDB 5CHTA 1THEA 1ZCMA 2R9CA 1TL9A 1PPPA 4NV8A 3HHAA 3HHIA 1AYVA 1FH0A 3H89A 4DMYA 2Y6EA 1ME4A 2HD5A 1AYUA 2AVWA 1PE6A 1W6FA 3WXFA 1CTEA 2FTDA 2FRAA 3I3TA 3P5UA 1YALA 1CSBB 4I07A 1GMYA 2BSZA 3KFQA 3KWBX 4RY2A 3QJ3A 3H6SA 2VHFA 1QOLA 2FYEA 3RVWA 1U9XA 1AU4A 4FJCA 1QXPA 4MSXA 3KSEA 3KKUA 3S3RA 1E2TA 1ICFA 4AXLA 5JA7A 4PP2E 1PXVA 2NQAA 4BS6A 2AUXA 2F7DA 1K3BB 2OULA 2VFBA 4YVAA 3F75A 3N3GA 2PBHA 2Y5BA 2ACTA 2R6NA 1GLOA 4G54A 4Q8HA 1ITOA 1MEGA 4I04A 2FT2A 1SNKA 1YK8A 1CVZA 1CS8A 1SP4B 1BY8A 4GUZA 1PPDA 4BGFA 2FQ9A 3ERVA 3GCBA 2BDZA 4YYRA 4QRXA 2DJGB 2FUDA 2GFOA 3WXEA 1MS6A 4NV7A 5CHVA 3F5VA 1BGOA 1A6RA 2XU5A 3MHSA 2DJFB 1MEMA 3H8BA 1EWLA 1DEUA 2YJ9A 3CBKA 1QMYA 1PADA 1GECE 4X6JA 2NQDB 6PADA 5J94A 3M99A 2HHNA 1BP4A 2NQIA 3WXGA 3C9EA 2R9NA 3QT4A 1PBHA 1Y08A 2R9MA 4PI3A 3BOWA 2B1MA 3DF0A 3S3QA 5CVMA 3E1ZB 1CV8A 3I06A 3D9WA 2G8EA 2C0YA 3OVXA 1XKGA 1VJVA 4MZOA 4YYWA 3BWKA 4YV8A 1KXRA 3H8CA 4CZWA 1YVBA 1U9WA 4P6EA 3N3KA 3OF9A 3P5VA 2HXZA 3PBHA 4N4ZA 1AIMA 2R9FA 1U9VA 3MORA 1YT7A 2O6XA 3USVA 3ZUAA 2DC8A 2FO5A 1EF7A 1IWDA 2JQGR 3O1GA 4YYUA 2ATOA 3PDFA 2F1GA 1X9YA 2YJ2A 4W5BA 3TNXA 1AU3A 3B79A 5EGWA 3IEJA 3OF8A 2FRQA 5JH3A 1EWMA 2DC7A 2ARYA 2DZYA 3D6SA 2XU3A 2DC6A 1KFXL 4KLBA 2E01A 5CVNB 4QRVA 1Y4HA 3OVZA 5K16A 2AYOA 3IV2A 2P7UA 1TLOA 4QRGA 8PCHA 5A24A 3CBJA 3OISA 2YJ8A 1MDWA 3H7DA 1BQIA 3KX1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZIV A;  2OP3 A;  2XU4 A;  1QDQ A;  1YK7 A;  3BPF A;  1KFU L;  1MHW A;  3PNR A;  2B1N A;  3CH2 X;  3V6C A;  4FK5 A;  1U5I A;  7PCK A;  1CQD A;  3P5X A;  4CDE B;  2E00 A;  1STF E;  4QH6 A;  2G6D A;  3K24 A;  2GHU A;  4CDC B;  1CJL A;  4P6G A;  1JQP A;  3RVX A;  1Q6K A;  1AYW A;  4X6I A;  4PP1 A;  2E02 A;  4YYS A;  1F2C A;  2YJC A;  1NB3 A;  2WBF X;  3BPM A;  1PIP A;  2IBI A;  1PPN A;  1O0E A;  2E03 A;  3PW3 A;  2R9O A;  2AYN A;  5EF4 A;  1HUC B;  3K8U A;  1NLJ A;  3P5W A;  2BDL A;  4PAD A;  1EWO A;  1TU6 A;  2YJB A;  1CB5 A;  1M6D A;  2HH5 A;  4OEM A;  2P0R A;  5F02 A;  4I05 A;  2CB5 A;  1DF0 A;  4FIP A;  1ME3 A;  3NHE A;  1F2A A;  4XUI A;  4YYQ A;  2DCB A;  4DMX A;  4YYV A;  4W4U A;  4HWY A;  4CDF B;  3HD3 A;  2H7J A;  4QBB A;  3LXS A;  4Q8G A;  3QSD A;  1NL6 A;  2DCD A;  4K7C A;  1VSN A;  3RVV A;  4OEL A;  2G8J A;  1EWP A;  2JQF R;  4WA6 A;  2AIM A;  3IHP A;  4X6H A;  3AI8 A;  2DZZ A;  1POP A;  4BQV A;  3MHH A;  1AEC A;  4BPV A;  3V6E A;  4BSQ A;  2PNS A;  3N4C A;  4AXM A;  4BS5 A;  3HWN A;  3KWZ A;  1F29 A;  1PPO A;  1GCB A;  2PAD A;  4ZUX U;  1U9Q X;  3CH3 X;  1KHP A;  1AU2 A;  1PCI A;  5FPW A;  3KW9 A;  3IUT A;  4MZS A;  2CIO A;  3O0U A;  1NQC A;  3IOQ A;  5CVO B;  2G7Y A;  3BCN A;  2DCA A;  1AU0 A;  3K9M A;  1S4V A;  1ATK A;  1NB5 A;  3IMA A;  1CPJ A;  3U8E A;  2AS8 A;  1KHQ A;  2OZ2 A;  2PRE A;  3LFY A;  1NPZ A;  2AUZ A;  2VHS A;  4XR7 A;  1F2B A;  4N79 A;  5PAD A;  1MIR A;  2NQG A;  4N8W A;  3MTN A;  2DCC A;  2DC9 A;  2XU1 A;  3BC3 A;  4W5C A;  2P86 A;  2IPP B;  9PAP A;  2AU1 A;  4CDD B;  5CHT A;  1THE A;  1ZCM A;  2R9C A;  1TL9 A;  1PPP A;  3HHA A;  3HHI A;  1AYV A;  1FH0 A;  3H89 A;  4DMY A;  2Y6E A;  1ME4 A;  2HD5 A;  1AYU A;  2AVW A;  1PE6 A;  3WXF A;  1CTE A;  2FTD A;  2FRA A;  3I3T A;  3P5U A;  1YAL A;  1CSB B;  4I07 A;  1GMY A;  3KFQ A;  3KWB X;  4RY2 A;  3QJ3 A;  3H6S A;  2VHF A;  1QOL A;  2FYE A;  3RVW A;  1U9X A;  1AU4 A;  4FJC A;  1QXP A;  4MSX A;  3KSE A;  3KKU A;  3S3R A;  1ICF A;  4AXL A;  5JA7 A;  4PP2 E;  1PXV A;  2NQA A;  4BS6 A;  2AUX A;  2F7D A;  1K3B B;  2OUL A;  4YVA A;  3F75 A;  3N3G A;  2PBH A;  2Y5B A;  2ACT A;  2R6N A;  1GLO A;  4G54 A;  4Q8H A;  1ITO A;  1MEG A;  4I04 A;  2FT2 A;  1SNK A;  1YK8 A;  1CVZ A;  1CS8 A;  1SP4 B;  1BY8 A;  1PPD A;  2FQ9 A;  3ERV A;  3GCB A;  2BDZ A;  4YYR A;  4QRX A;  2DJG B;  2FUD A;  2GFO A;  3WXE A;  1MS6 A;  5CHV A;  3F5V A;  1BGO A;  1A6R A;  2XU5 A;  3MHS A;  2DJF B;  1MEM A;  3H8B A;  1EWL A;  1DEU A;  2YJ9 A;  3CBK A;  1QMY A;  1PAD A;  1GEC E;  4X6J A;  2NQD B;  6PAD A;  5J94 A;  3M99 A;  2HHN A;  1BP4 A;  2NQI A;  3WXG A;  3C9E A;  2R9N A;  3QT4 A;  1PBH A;  1Y08 A;  2R9M A;  4PI3 A;  3BOW A;  2B1M A;  3DF0 A;  3S3Q A;  5CVM A;  3E1Z B;  1CV8 A;  3I06 A;  2G8E A;  2C0Y A;  3OVX A;  1XKG A;  1VJV A;  4MZO A;  4YYW A;  3BWK A;  4YV8 A;  1KXR A;  3H8C A;  4CZW A;  1YVB A;  1U9W A;  4P6E A;  3N3K A;  3OF9 A;  3P5V A;  2HXZ A;  3PBH A;  4N4Z A;  1AIM A;  2R9F A;  1U9V A;  3MOR A;  1YT7 A;  2O6X A;  3USV A;  3ZUA A;  2DC8 A;  2FO5 A;  1EF7 A;  1IWD A;  2JQG R;  3O1G A;  4YYU A;  2ATO A;  3PDF A;  2F1G A;  1X9Y A;  2YJ2 A;  4W5B A;  3TNX A;  1AU3 A;  3B79 A;  5EGW A;  3IEJ A;  3OF8 A;  2FRQ A;  5JH3 A;  1EWM A;  2DC7 A;  2ARY A;  2DZY A;  3D6S A;  2XU3 A;  2DC6 A;  1KFX L;  4KLB A;  2E01 A;  5CVN B;  4QRV A;  1Y4H A;  3OVZ A;  5K16 A;  2AYO A;  3IV2 A;  2P7U A;  1TLO A;  4QRG A;  8PCH A;  5A24 A;  3CBJ A;  3OIS A;  2YJ8 A;  1MDW A;  3H7D A;  1BQI A;  3KX1 A; 
#chains in the Genus database with same CATH topology
 1ZIV A;  2OP3 A;  2XU4 A;  5EZS A;  1QDQ A;  1YK7 A;  3BPF A;  1KFU L;  1MHW A;  3PNR A;  2B1N A;  3CH2 X;  3V6C A;  4FK5 A;  1U5I A;  7PCK A;  1CQD A;  3P5X A;  4CDE B;  2E00 A;  1STF E;  2G6D A;  3K24 A;  4QH6 A;  2GHU A;  4IP3 A;  4CDC B;  1CJL A;  4P6G A;  1JQP A;  3RVX A;  1Q6K A;  1AYW A;  4X6I A;  2FE8 A;  4PP1 A;  2E02 A;  4YYS A;  1F2C A;  2YJC A;  1NB3 A;  2WBF X;  3BPM A;  1PIP A;  2IBI A;  4BOS A;  1PPN A;  1O0E A;  2E03 A;  3PW3 A;  2R9O A;  2AYN A;  5EF4 A;  1HUC B;  3PT2 A;  3K8U A;  1NLJ A;  3P5W A;  2BDL A;  4HXD B;  4PAD A;  4A5U A;  3PSE A;  1EWO A;  1TU6 A;  2YJB A;  1CB5 A;  1M6D A;  2HH5 A;  4OEM A;  2P0R A;  5F02 A;  4I05 A;  2CB5 A;  1DF0 A;  4FIP A;  4OW0 A;  1ME3 A;  3NHE A;  1F2A A;  4XUI A;  4YYQ A;  2DCB A;  4DMX A;  4YYV A;  4W4U A;  2J7Q C;  4HWY A;  4CDF B;  3HD3 A;  2H7J A;  4QBB A;  3LXS A;  4Q8G A;  3QSD A;  1NL6 A;  2DCD A;  3MTV A;  4K7C A;  2AGA A;  1VSN A;  3RVV A;  4OEL A;  2G8J A;  1EWP A;  2JQF R;  4REZ A;  4WA6 A;  2AIM A;  3IHP A;  4X6H A;  3AI8 A;  2DZZ A;  1POP A;  4BQV A;  3MHH A;  1AEC A;  4BPV A;  3V6E A;  4BSQ A;  2PNS A;  3N4C A;  4AXM A;  4BS5 A;  3HWN A;  3KWZ A;  1UKF A;  4GUA A;  1F29 A;  1PPO A;  1GCB A;  2PAD A;  4ZUX U;  3PHW A;  1U9Q X;  3CH3 X;  1KHP A;  1AU2 A;  1PCI A;  2DOS A;  5FPW A;  1DKI A;  3IUT A;  3KW9 A;  4MZS A;  5JZE A;  2CIO A;  3O0U A;  3RNV A;  1NQC A;  3IOQ A;  5CVO B;  4OVZ B;  4RKX A;  2G7Y A;  3BCN A;  2DCA A;  3C0R A;  1AU0 A;  3K9M A;  1S4V A;  1ATK A;  3TMP A;  4D8I A;  1NB5 A;  4BOQ A;  3IMA A;  1CPJ A;  3W30 A;  3U8E A;  2AS8 A;  1KHQ A;  2OZ2 A;  2PRE A;  3LFY A;  1NPZ A;  2JTC A;  2AUZ A;  2VHS A;  4XR7 A;  1F2B A;  4N79 A;  2BTW B;  3OQC A;  5PAD A;  1MIR A;  2NQG A;  4N8W A;  4M0W A;  3MTN A;  2DCC A;  2DC9 A;  2XU1 A;  3BC3 A;  3PHX A;  4W5C A;  2P86 A;  4RF0 A;  2IPP B;  9PAP A;  2AU1 A;  4CDD B;  5CHT A;  1THE A;  1ZCM A;  2R9C A;  1TL9 A;  1PPP A;  3HHA A;  3HHI A;  1AYV A;  1FH0 A;  3H89 A;  4DMY A;  2Y6E A;  1ME4 A;  2HD5 A;  1AYU A;  4D8E A;  2AVW A;  1PE6 A;  4BOZ A;  4MI7 A;  3WXF A;  1CTE A;  2FTD A;  3IFU A;  2FRA A;  3I3T A;  3P5U A;  1YAL A;  1CSB B;  3MJ5 A;  4I07 A;  1GMY A;  3KFQ A;  3KWB X;  4RY2 A;  3QJ3 A;  3H6S A;  2VHF A;  1QOL A;  2FYE A;  3RVW A;  4MM3 B;  1U9X A;  1AU4 A;  4FJC A;  1QXP A;  3B21 A;  3KSE A;  4MSX A;  2JRI A;  3KKU A;  3BBA A;  3S3R A;  1ICF A;  4AXL A;  5JA7 A;  4PP2 E;  1PXV A;  2NQA A;  4BS6 A;  2AUX A;  2J7Q A;  1PVJ A;  2F7D A;  3TRK A;  1K3B B;  2OUL A;  4YVA A;  3F75 A;  3N3G A;  2PBH A;  2Y5B A;  2ACT A;  2R6N A;  1GLO A;  4G54 A;  4Q8H A;  1ITO A;  1MEG A;  4I04 A;  2FT2 A;  1SNK A;  1YK8 A;  1CVZ A;  2Z84 A;  1CS8 A;  1SP4 B;  1BY8 A;  1PPD A;  4D8B A;  3MP2 A;  2FQ9 A;  3ERV A;  3GCB A;  2BDZ A;  4YYR A;  4QRX A;  2DJG B;  2FUD A;  3PHU A;  2GFO A;  3WXE A;  1MS6 A;  2BU3 A;  3O65 A;  5CHV A;  5KO3 A;  3F5V A;  1BGO A;  1A6R A;  2XU5 A;  3MHS A;  4WUR A;  2DJF B;  1MEM A;  3H8B A;  1EWL A;  1DEU A;  2YJ9 A;  3CBK A;  1QMY A;  1PAD A;  1GEC E;  4X6J A;  2NQD B;  6PAD A;  5J94 A;  3M99 A;  2HHN A;  1BP4 A;  2NQI A;  3PRP A;  3WXG A;  3C9E A;  3W31 A;  2R9N A;  3QT4 A;  1PBH A;  1Y08 A;  2R9M A;  4PI3 A;  3BOW A;  2B1M A;  3DF0 A;  3S3Q A;  5CVM A;  3E1Z B;  1CV8 A;  3I06 A;  2G8E A;  2C0Y A;  3OVX A;  1XKG A;  4OVZ A;  1VJV A;  4MZO A;  3ZNH A;  4IUM A;  4BOU A;  4YYW A;  3BWK A;  4YV8 A;  1KXR A;  3H8C A;  4CZW A;  1YVB A;  1U9W A;  4P6E A;  3N3K A;  3OF9 A;  3P5V A;  2HXZ A;  3E9S A;  3PBH A;  4BOP A;  4RF1 A;  4N4Z A;  1AIM A;  2R9F A;  3BY4 A;  1U9V A;  3MOR A;  1YT7 A;  2O6X A;  3USV A;  2BTW A;  2UZJ A;  4XZX A;  4ZTB A;  3ZUA A;  2DC8 A;  2FO5 A;  1EF7 A;  1IWD A;  3PRM A;  5EZQ A;  2JQG R;  3O1G A;  5E6J A;  4YYU A;  2ATO A;  3PDF A;  4PT5 A;  2F1G A;  1X9Y A;  2HWK A;  2YJ2 A;  4W5B A;  3TNX A;  4P16 A;  1AU3 A;  1YZB A;  3B79 A;  5EGW A;  3IEJ A;  3OF8 A;  2FRQ A;  5JH3 A;  1EWM A;  2DC7 A;  4R3D A;  2ARY A;  2DZY A;  3D6S A;  2XU3 A;  2DC6 A;  1KFX L;  4KLB A;  2E01 A;  5CVN B;  3BB7 A;  4QRV A;  1Y4H A;  3OVZ A;  5K16 A;  2AYO A;  4RNA A;  3IV2 A;  2P7U A;  1TLO A;  4QRG A;  8PCH A;  5A24 A;  3CBJ A;  3OIS A;  2YJ8 A;  1MDW A;  3H7D A;  1BQI A;  3KX1 A; 
#chains in the Genus database with same CATH homology
 1ZIV A;  2OP3 A;  2XU4 A;  1QDQ A;  1YK7 A;  3BPF A;  1KFU L;  1MHW A;  3PNR A;  2B1N A;  3CH2 X;  3V6C A;  4FK5 A;  1U5I A;  7PCK A;  1CQD A;  3P5X A;  4CDE B;  2E00 A;  1STF E;  2G6D A;  3K24 A;  4QH6 A;  2GHU A;  4CDC B;  1CJL A;  4P6G A;  1JQP A;  3RVX A;  1Q6K A;  1AYW A;  4X6I A;  4PP1 A;  2E02 A;  4YYS A;  1F2C A;  2YJC A;  1NB3 A;  2WBF X;  3BPM A;  1PIP A;  2IBI A;  4B55 A;  1PPN A;  1O0E A;  2E03 A;  3PW3 A;  2R9O A;  2AYN A;  5EF4 A;  1HUC B;  3K8U A;  1NLJ A;  3P5W A;  2BDL A;  4PAD A;  1EWO A;  1TU6 A;  2YJB A;  1CB5 A;  1M6D A;  2HH5 A;  4OEM A;  2P0R A;  4C5P A;  5F02 A;  4I05 A;  2CB5 A;  1DF0 A;  4FIP A;  1ME3 A;  3NHE A;  1F2A A;  4XUI A;  4YYQ A;  2DCB A;  4DMX A;  4YYV A;  4W4U A;  4HWY A;  4CDF B;  3HD3 A;  2H7J A;  4QBB A;  3LXS A;  4Q8G A;  3QSD A;  1NL6 A;  2DCD A;  4K7C A;  1VSN A;  3RVV A;  4OEL A;  2G8J A;  1EWP A;  2JQF R;  1W4T A;  4WA6 A;  2AIM A;  3IHP A;  4X6H A;  3AI8 A;  2DZZ A;  1POP A;  4BQV A;  3MHH A;  1AEC A;  4BPV A;  3V6E A;  4BSQ A;  2PNS A;  3N4C A;  4AXM A;  4BS5 A;  3HWN A;  3KWZ A;  1F29 A;  1PPO A;  1GCB A;  2PAD A;  4ZUX U;  1U9Q X;  3CH3 X;  1KHP A;  1AU2 A;  1PCI A;  5FPW A;  3KW9 A;  3IUT A;  4MZS A;  2CIO A;  3O0U A;  1NQC A;  3IOQ A;  5CVO B;  2VFC A;  2G7Y A;  3BCN A;  2DCA A;  1AU0 A;  3LTW A;  3K9M A;  1S4V A;  1ATK A;  1NB5 A;  3IMA A;  1CPJ A;  3U8E A;  2AS8 A;  1KHQ A;  2OZ2 A;  2PRE A;  3LFY A;  1NPZ A;  2AUZ A;  2VHS A;  1W5R A;  4XR7 A;  1F2B A;  4N79 A;  5PAD A;  1MIR A;  2NQG A;  4N8W A;  3MTN A;  2DCC A;  2DC9 A;  1GX3 A;  2XU1 A;  3BC3 A;  4W5C A;  2P86 A;  2IPP B;  9PAP A;  2AU1 A;  4CDD B;  5CHT A;  1THE A;  1ZCM A;  2R9C A;  1TL9 A;  1PPP A;  4NV8 A;  3HHA A;  3HHI A;  1AYV A;  1FH0 A;  3H89 A;  4DMY A;  2Y6E A;  1ME4 A;  2HD5 A;  1AYU A;  2AVW A;  1PE6 A;  1W6F A;  3WXF A;  1CTE A;  2FTD A;  2FRA A;  3I3T A;  3P5U A;  1YAL A;  1CSB B;  4I07 A;  1GMY A;  2BSZ A;  3KFQ A;  3KWB X;  4RY2 A;  3QJ3 A;  3H6S A;  2VHF A;  1QOL A;  2FYE A;  3RVW A;  1U9X A;  1AU4 A;  4FJC A;  1QXP A;  4MSX A;  3KSE A;  3KKU A;  3S3R A;  1E2T A;  1ICF A;  4AXL A;  5JA7 A;  4PP2 E;  1PXV A;  2NQA A;  4BS6 A;  2AUX A;  2F7D A;  1K3B B;  2OUL A;  2VFB A;  4YVA A;  3F75 A;  3N3G A;  2PBH A;  2Y5B A;  2ACT A;  2R6N A;  1GLO A;  4G54 A;  4Q8H A;  1ITO A;  1MEG A;  4I04 A;  2FT2 A;  1SNK A;  1YK8 A;  1CVZ A;  1CS8 A;  1SP4 B;  1BY8 A;  4GUZ A;  1PPD A;  4BGF A;  2FQ9 A;  3ERV A;  3GCB A;  2BDZ A;  4YYR A;  4QRX A;  2DJG B;  2FUD A;  2GFO A;  3WXE A;  1MS6 A;  4NV7 A;  5CHV A;  3F5V A;  1BGO A;  1A6R A;  2XU5 A;  3MHS A;  2DJF B;  1MEM A;  3H8B A;  1EWL A;  1DEU A;  2YJ9 A;  3CBK A;  1QMY A;  1PAD A;  1GEC E;  4X6J A;  2NQD B;  6PAD A;  5J94 A;  3M99 A;  2HHN A;  1BP4 A;  2NQI A;  3WXG A;  3C9E A;  2R9N A;  3QT4 A;  1PBH A;  1Y08 A;  2R9M A;  4PI3 A;  3BOW A;  2B1M A;  3DF0 A;  3S3Q A;  5CVM A;  3E1Z B;  1CV8 A;  3I06 A;  3D9W A;  2G8E A;  2C0Y A;  3OVX A;  1XKG A;  1VJV A;  4MZO A;  4YYW A;  3BWK A;  4YV8 A;  1KXR A;  3H8C A;  4CZW A;  1YVB A;  1U9W A;  4P6E A;  3N3K A;  3OF9 A;  3P5V A;  2HXZ A;  3PBH A;  4N4Z A;  1AIM A;  2R9F A;  1U9V A;  3MOR A;  1YT7 A;  2O6X A;  3USV A;  3ZUA A;  2DC8 A;  2FO5 A;  1EF7 A;  1IWD A;  2JQG R;  3O1G A;  4YYU A;  2ATO A;  3PDF A;  2F1G A;  1X9Y A;  2YJ2 A;  4W5B A;  3TNX A;  1AU3 A;  3B79 A;  5EGW A;  3IEJ A;  3OF8 A;  2FRQ A;  5JH3 A;  1EWM A;  2DC7 A;  2ARY A;  2DZY A;  3D6S A;  2XU3 A;  2DC6 A;  1KFX L;  4KLB A;  2E01 A;  5CVN B;  4QRV A;  1Y4H A;  3OVZ A;  5K16 A;  2AYO A;  3IV2 A;  2P7U A;  1TLO A;  4QRG A;  8PCH A;  5A24 A;  3CBJ A;  3OIS A;  2YJ8 A;  1MDW A;  3H7D A;  1BQI A;  3KX1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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