3CBKA

Chagasin-cathepsin b
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
257
structure length
257
Chain Sequence
LKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNGARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Cathepsin B
total genus 60
structure length 257
sequence length 257
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2008-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3cbkA00
4G54A 2Y5BA 1Y4HA 1ICFA 4CZWA 2AYOA 4QRVA 3I06A 2E03A 3KSEA 2VHFA 2O6XA 2PADA 1U5IA 2B1MA 4ZUXU 3S3QA 1QMYA 5CVMA 1PBHA 3P5VA 4CDCB 2AU1A 1MEMA 3GCBA 2DZZA 4PI3A 1TU6A 3IMAA 1CQDA 1QOLA 1PADA 1BY8A 2ARYA 2DCCA 2DC8A 3P5WA 4OEMA 1POPA 1F2BA 1PE6A 1MHWA 3N3KA 4W5BA 3NHEA 2ATOA 2FYEA 4BQVA 2DJFB 3BPMA 2B1NA 2E00A 2YJCA 1CPJA 2AYNA 4CDFB 1CB5A 3ERVA 1NQCA 2GHUA 2G8JA 2P7UA 4CDDB 6PADA 1NB3A 5CHTA 2OULA 4BS6A 2CIOA 3KWZA 1BP4A 3OF9A 3IUTA 3MHSA 2HD5A 4AXLA 1ZCMA 3MHHA 1DF0A 3ZUAA 4YYVA 5F02A 4YYUA 4YV8A 3F75A 3PNRA 1ZIVA 1S4VA 3RVVA 4QRGA 4N8WA 5JA7A 3B79A 1CJLA 3OVZA 2IPPB 1CVZA 3RVWA 2G6DA 2OP3A 1TL9A 2ACTA 2JQGR 2AUZA 4WA6A 1NLJA 1QDQA 1K3BB 4I07A 3KW9A 1U9XA 1TLOA 1CS8A 4W5CA 1PIPA 4N79A 2R9NA 1PCIA 5JH3A 1EWLA 5CVOB 2CB5A 2XU5A 1F2CA 3IHPA 2FO5A 1HUCB 1BGOA 4PADA 2DC6A 3BC3A 2R9CA 1GLOA 1YALA 1PPOA 4FK5A 4MSXA 3TNXA 3BWKA 2XU3A 4BPVA 1U9VA 2P86A 3HHAA 1KHPA 3DF0A 1AIMA 2DC9A 2AVWA 1F2AA 2BDZA 1AECA 3C9EA 1AYWA 2YJ2A 1PPDA 2PBHA 4CDEB 4Q8HA 2DCDA 2YJBA 3PW3A 3BCNA 2HHNA 5EF4A 1EF7A 3M99A 4AXMA 1PPPA 4P6EA 3CH2X 1AU3A 1M6DA 2R9FA 1GECE 1KHQA 4YVAA 4FJCA 3F5VA 2E02A 1AYUA 4Q8GA 4DMYA 3H89A 5EGWA 1SP4B 2F7DA 1EWMA 9PAPA 4QRXA 1X9YA 1XKGA 1ITOA 3OF8A 2H7JA 1CTEA 3QJ3A 4HWYA 1DEUA 5A24A 4N4ZA 2NQAA 5FPWA 2GFOA 4YYQA 4BS5A 2DCAA 2JQFR 1CV8A 2XU1A 2VHSA 3KWBX 1AU4A 3LXSA 3N4CA 4KLBA 2DC7A 3CBJA 3HWNA 2FUDA 2FTDA 2DJGB 2E01A 2NQGA 2FRAA 2NQIA 1AYVA 1BQIA 3H8CA 1ATKA 3AI8A 4PP2E 2G7YA 3HHIA 1YT7A 1PPNA 1MIRA 3IV2A 3U8EA 2R6NA 3WXFA 2AUXA 1EWPA 1U9WA 2HH5A 1IWDA 2DZYA 2P0RA 2C0YA 3IOQA 4X6IA 3OISA 4DMXA 1SNKA 3BPFA 4P6GA 3QSDA 3D6SA 1MDWA 3O1GA 3V6EA 1ME4A 3HD3A 2R9OA 2HXZA 3MTNA 1PXVA 1Y08A 1KFXL 4MZOA 2BDLA 1ME3A 3KX1A 4PP1A 1NB5A 2Y6EA 3N3GA 1F29A 1AU0A 4QBBA 3LFYA 5CHVA 1MEGA 3CBKA 4YYWA 3RVXA 4W4UA 4X6JA 4XR7A 5CVNB 1THEA 4XUIA 3S3RA 1Q6KA 1STFE 8PCHA 1VSNA 1KXRA 3OVXA 3K8UA 3IEJA 2FQ9A 3PDFA 3I3TA 1EWOA 4X6HA 2G8EA 1U9QX 3P5XA 3O0UA 1QXPA 2IBIA 1YK7A 7PCKA 4QH6A 4BSQA 3BOWA 4MZSA 1AU2A 5J94A 4FIPA 1A6RA 1GMYA 2WBFX 3K9MA 4K7CA 4YYRA 1FH0A 1NPZA 3P5UA 3V6CA 3WXEA 3MORA 2FT2A 3KFQA 2FRQA 2YJ8A 1YVBA 1O0EA 4RY2A 2R9MA 2AS8A 4I04A 2NQDB 5K16A 3E1ZB 1NL6A 4OELA 3H7DA 2DCBA 1JQPA 2F1GA 1CSBB 2PNSA 2YJ9A 1KFUL 2PREA 3QT4A 3PBHA 2XU4A 5PADA 1MS6A 3CH3X 3K24A 3USVA 3WXGA 4I05A 1GCBA 2AIMA 1YK8A 2OZ2A 3KKUA 3H6SA 1VJVA 3H8BA 4YYSA
chains in the Genus database with same CATH superfamily
4G54A 2Y5BA 1Y4HA 1ICFA 4CZWA 2UZJA 2AYOA 4QRVA 3I06A 4RKXA 2E03A 3KSEA 2VHFA 2O6XA 2PADA 1U5IA 2B1MA 4ZUXU 3S3QA 1QMYA 5CVMA 1PBHA 3P5VA 4CDCB 2AU1A 3W30A 1MEMA 3GCBA 2DZZA 3RNVA 4PI3A 1TU6A 3IMAA 1CQDA 1QOLA 4OVZB 1PADA 1BY8A 2ARYA 3W31A 2DCCA 2DC8A 3P5WA 3MP2A 4OEMA 1POPA 1F2BA 1PE6A 1MHWA 3N3KA 4W5BA 3NHEA 2ATOA 2FYEA 4BQVA 2DJFB 3BPMA 4D8BA 2B1NA 2E00A 2YJCA 1CPJA 2AYNA 4CDFB 1CB5A 3ERVA 4WURA 1NQCA 4RF1A 2GHUA 2G8JA 2P7UA 4CDDB 4MM3B 6PADA 1NB3A 5CHTA 2OULA 4BS6A 2CIOA 3KWZA 1BP4A 3OF9A 3IUTA 4RNAA 3MHSA 2HD5A 4AXLA 1ZCMA 3MHHA 1DF0A 3ZUAA 4YYVA 5F02A 4YYUA 4YV8A 3F75A 3PNRA 1ZIVA 1S4VA 3RVVA 3PHUA 4QRGA 4N8WA 1UKFA 5JA7A 3B79A 1CJLA 3OVZA 2IPPB 1CVZA 3RVWA 2G6DA 2OP3A 1TL9A 2ACTA 2JQGR 2AUZA 4GUAA 4WA6A 1NLJA 1QDQA 1K3BB 2BTWB 4I07A 3KW9A 1U9XA 1TLOA 1CS8A 4W5CA 1PIPA 4N79A 2R9NA 1PCIA 5JH3A 1EWLA 5CVOB 2CB5A 2XU5A 1F2CA 3IHPA 2FO5A 1HUCB 1BGOA 1YZBA 4PADA 2DC6A 3BC3A 2R9CA 1GLOA 1YALA 1PPOA 4FK5A 4MSXA 3TNXA 3BWKA 2XU3A 2JTCA 1U9VA 4BPVA 2P86A 3HHAA 1KHPA 3DF0A 1AIMA 2DC9A 2AVWA 1F2AA 2BDZA 1AECA 3C9EA 5EZSA 2J7QA 3O65A 1AYWA 2YJ2A 2HWKA 1PPDA 2PBHA 4CDEB 4Q8HA 2DCDA 2YJBA 3PW3A 4OW0A 3BCNA 2HHNA 5EF4A 5KO3A 1EF7A 3M99A 4AXMA 1PPPA 4P6EA 3PT2A 3CH2X 3BB7A 1AU3A 1M6DA 2R9FA 3PRMA 1GECE 1KHQA 4YVAA 4FJCA 3F5VA 2E02A 1AYUA 4Q8GA 4DMYA 2J7QC 3H89A 5EGWA 4BOPA 1SP4B 2F7DA 1EWMA 9PAPA 4QRXA 1X9YA 1XKGA 1ITOA 4ZTBA 3OF8A 2H7JA 1CTEA 3QJ3A 4HWYA 1DEUA 5A24A 4N4ZA 2NQAA 2Z84A 5FPWA 2GFOA 4YYQA 3MJ5A 3MTVA 3BY4A 3PHXA 4BS5A 2DCAA 2JQFR 1CV8A 4R3DA 2XU1A 4A5UA 2VHSA 4RF0A 3KWBX 1AU4A 3LXSA 3N4CA 2AGAA 4KLBA 2DC7A 3CBJA 3HWNA 2FUDA 2FTDA 2DJGB 2E01A 2NQGA 2FRAA 2NQIA 2DOSA 1AYVA 1BQIA 3H8CA 1ATKA 3AI8A 4PP2E 2G7YA 3HHIA 1YT7A 1PPNA 1MIRA 3IV2A 3U8EA 2R6NA 5EZQA 3WXFA 4BOSA 2AUXA 1DKIA 1EWPA 1U9WA 2HH5A 1IWDA 2DZYA 2P0RA 4BOUA 2C0YA 3IOQA 4X6IA 3OISA 4DMXA 1SNKA 3BPFA 4P6GA 3QSDA 3D6SA 1MDWA 3O1GA 3V6EA 1ME4A 3HD3A 2R9OA 2HXZA 3MTNA 1PXVA 1Y08A 1KFXL 4MZOA 2BDLA 1ME3A 3KX1A 4IP3A 4BOZA 4PP1A 1NB5A 2Y6EA 5E6JA 3N3GA 1F29A 1AU0A 3TMPA 3IFUA 4HXDB 4QBBA 3LFYA 4M0WA 5CHVA 1MEGA 3PHWA 3CBKA 4YYWA 4D8IA 3RVXA 4W4UA 4X6JA 4XR7A 5CVNB 1THEA 4XUIA 3S3RA 4IUMA 2BU3A 1Q6KA 1STFE 4REZA 3ZNHA 8PCHA 3TRKA 1VSNA 1KXRA 3OVXA 3K8UA 3IEJA 2FQ9A 3PDFA 3I3TA 1EWOA 3C0RA 4X6HA 2G8EA 1U9QX 3P5XA 3O0UA 1QXPA 2IBIA 1YK7A 7PCKA 4QH6A 2BTWA 4BSQA 3BOWA 4MZSA 1AU2A 4BOQA 5J94A 4FIPA 1A6RA 1GMYA 2WBFX 3K9MA 4K7CA 4P16A 4YYRA 1FH0A 1NPZA 3P5UA 3V6CA 3WXEA 3MORA 2FT2A 3KFQA 4D8EA 3BBAA 2FRQA 2YJ8A 1YVBA 1O0EA 4RY2A 1PVJA 2R9MA 2AS8A 4I04A 3OQCA 2NQDB 3PRPA 2JRIA 5K16A 3PSEA 4XZXA 2FE8A 3E1ZB 4MI7A 1NL6A 4OELA 3H7DA 2DCBA 1JQPA 2F1GA 1CSBB 2PNSA 2YJ9A 4OVZA 1KFUL 2PREA 5JZEA 3E9SA 3QT4A 3PBHA 2XU4A 5PADA 1MS6A 3CH3X 3K24A 3USVA 3WXGA 4I05A 1GCBA 2AIMA 1YK8A 4PT5A 2OZ2A 3KKUA 3H6SA 3B21A 1VJVA 3H8BA 4YYSA
chains in the Genus database with same CATH topology
4G54A 2Y5BA 1Y4HA 1ICFA 4CZWA 2AYOA 4QRVA 3I06A 2E03A 3KSEA 2VHFA 2O6XA 2PADA 1U5IA 2B1MA 4ZUXU 3S3QA 1QMYA 5CVMA 1PBHA 3P5VA 4CDCB 2AU1A 1MEMA 3GCBA 2DZZA 4PI3A 1TU6A 3IMAA 1CQDA 1QOLA 1PADA 1BY8A 2ARYA 2DCCA 2DC8A 3P5WA 4OEMA 1POPA 1F2BA 1PE6A 1MHWA 3N3KA 4W5BA 3NHEA 2ATOA 2FYEA 4BQVA 2DJFB 3BPMA 2B1NA 2E00A 2YJCA 1CPJA 2AYNA 4CDFB 1CB5A 3ERVA 1NQCA 2GHUA 2G8JA 2P7UA 4CDDB 6PADA 1NB3A 5CHTA 1GX3A 2OULA 4BS6A 2CIOA 3KWZA 1BP4A 3OF9A 3IUTA 3MHSA 2HD5A 1W4TA 4AXLA 1ZCMA 3MHHA 1DF0A 3ZUAA 4YYVA 5F02A 4YYUA 4YV8A 3F75A 3PNRA 1ZIVA 1S4VA 3RVVA 4QRGA 4N8WA 5JA7A 3B79A 1CJLA 3OVZA 2IPPB 1CVZA 3RVWA 2G6DA 2OP3A 1TL9A 2ACTA 2JQGR 2AUZA 4WA6A 1NLJA 1QDQA 1K3BB 4I07A 3KW9A 1U9XA 1TLOA 1CS8A 4W5CA 1PIPA 4N79A 2R9NA 1PCIA 5JH3A 1EWLA 5CVOB 2CB5A 2XU5A 1F2CA 3IHPA 2FO5A 1E2TA 1HUCB 1BGOA 4PADA 2DC6A 3BC3A 2R9CA 1GLOA 1YALA 1PPOA 4FK5A 4MSXA 3TNXA 3BWKA 2XU3A 4BPVA 1U9VA 1W5RA 2P86A 3HHAA 1KHPA 3DF0A 1AIMA 2DC9A 2AVWA 1F2AA 2BDZA 1AECA 3C9EA 1AYWA 2YJ2A 1PPDA 2PBHA 4CDEB 4Q8HA 2DCDA 2YJBA 3PW3A 3BCNA 2HHNA 3D9WA 2VFCA 5EF4A 1EF7A 3M99A 4AXMA 1PPPA 4P6EA 3CH2X 1AU3A 1M6DA 2R9FA 1GECE 1KHQA 4YVAA 4FJCA 3F5VA 2E02A 1AYUA 4Q8GA 4DMYA 3H89A 5EGWA 1SP4B 2F7DA 1EWMA 9PAPA 4QRXA 1X9YA 1XKGA 1ITOA 3OF8A 2H7JA 1CTEA 3QJ3A 4HWYA 1DEUA 5A24A 4N4ZA 2NQAA 5FPWA 2GFOA 4YYQA 4BS5A 2DCAA 2JQFR 1CV8A 2XU1A 2VHSA 3KWBX 1AU4A 3LXSA 3N4CA 4KLBA 2DC7A 3CBJA 3HWNA 2FUDA 2FTDA 4BGFA 2DJGB 2E01A 2NQGA 2FRAA 2NQIA 1AYVA 1BQIA 3H8CA 1ATKA 3AI8A 4PP2E 2G7YA 3HHIA 1YT7A 1PPNA 1MIRA 3IV2A 3U8EA 2R6NA 3WXFA 2AUXA 1EWPA 1U9WA 2HH5A 1IWDA 2DZYA 2P0RA 4B55A 2C0YA 3IOQA 4X6IA 3OISA 4DMXA 1SNKA 3BPFA 4P6GA 3QSDA 3D6SA 1MDWA 3O1GA 3V6EA 1ME4A 3HD3A 2R9OA 2HXZA 3MTNA 1PXVA 1Y08A 1KFXL 4MZOA 2BDLA 1ME3A 3KX1A 4PP1A 1NB5A 2Y6EA 3N3GA 1F29A 1AU0A 4QBBA 3LFYA 4C5PA 5CHVA 1MEGA 3CBKA 4YYWA 3RVXA 4W4UA 4X6JA 4NV8A 4XR7A 1THEA 5CVNB 4XUIA 3S3RA 1Q6KA 1STFE 8PCHA 1VSNA 1KXRA 3OVXA 3K8UA 3IEJA 2FQ9A 3PDFA 3I3TA 1EWOA 4X6HA 2G8EA 1U9QX 3P5XA 3O0UA 1QXPA 2IBIA 1YK7A 7PCKA 4QH6A 2VFBA 4BSQA 3BOWA 4MZSA 1AU2A 5J94A 4FIPA 1A6RA 1GMYA 2WBFX 3K9MA 4K7CA 4YYRA 1FH0A 1NPZA 3P5UA 3V6CA 3WXEA 3MORA 2FT2A 3KFQA 2FRQA 2YJ8A 1YVBA 1O0EA 4RY2A 2R9MA 2AS8A 4I04A 2NQDB 5K16A 1W6FA 3E1ZB 1NL6A 4OELA 3H7DA 2DCBA 1JQPA 2F1GA 1CSBB 2PNSA 2YJ9A 1KFUL 2PREA 3QT4A 3PBHA 2XU4A 5PADA 4GUZA 1MS6A 3CH3X 3K24A 3USVA 3WXGA 2BSZA 4I05A 1GCBA 2AIMA 3LTWA 1YK8A 4NV7A 2OZ2A 3KKUA 3H6SA 1VJVA 3H8BA 4YYSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G54 A;  2Y5B A;  1Y4H A;  1ICF A;  4CZW A;  2AYO A;  4QRV A;  3I06 A;  2E03 A;  3KSE A;  2VHF A;  2O6X A;  2PAD A;  1U5I A;  2B1M A;  4ZUX U;  3S3Q A;  1QMY A;  5CVM A;  1PBH A;  3P5V A;  4CDC B;  2AU1 A;  1MEM A;  3GCB A;  2DZZ A;  4PI3 A;  1TU6 A;  3IMA A;  1CQD A;  1QOL A;  1PAD A;  1BY8 A;  2ARY A;  2DCC A;  2DC8 A;  3P5W A;  4OEM A;  1POP A;  1F2B A;  1PE6 A;  1MHW A;  3N3K A;  4W5B A;  3NHE A;  2ATO A;  2FYE A;  4BQV A;  2DJF B;  3BPM A;  2B1N A;  2E00 A;  2YJC A;  1CPJ A;  2AYN A;  4CDF B;  1CB5 A;  3ERV A;  1NQC A;  2GHU A;  2G8J A;  2P7U A;  4CDD B;  6PAD A;  1NB3 A;  5CHT A;  2OUL A;  4BS6 A;  2CIO A;  3KWZ A;  1BP4 A;  3OF9 A;  3IUT A;  3MHS A;  2HD5 A;  4AXL A;  1ZCM A;  3MHH A;  1DF0 A;  3ZUA A;  4YYV A;  5F02 A;  4YYU A;  4YV8 A;  3F75 A;  3PNR A;  1ZIV A;  1S4V A;  3RVV A;  4QRG A;  4N8W A;  5JA7 A;  3B79 A;  1CJL A;  3OVZ A;  2IPP B;  1CVZ A;  3RVW A;  2G6D A;  2OP3 A;  1TL9 A;  2ACT A;  2JQG R;  2AUZ A;  4WA6 A;  1NLJ A;  1QDQ A;  1K3B B;  4I07 A;  3KW9 A;  1U9X A;  1TLO A;  1CS8 A;  4W5C A;  1PIP A;  4N79 A;  2R9N A;  1PCI A;  5JH3 A;  1EWL A;  5CVO B;  2CB5 A;  2XU5 A;  1F2C A;  3IHP A;  2FO5 A;  1HUC B;  1BGO A;  4PAD A;  2DC6 A;  3BC3 A;  2R9C A;  1GLO A;  1YAL A;  1PPO A;  4FK5 A;  4MSX A;  3TNX A;  3BWK A;  2XU3 A;  4BPV A;  1U9V A;  2P86 A;  3HHA A;  1KHP A;  3DF0 A;  1AIM A;  2DC9 A;  2AVW A;  1F2A A;  2BDZ A;  1AEC A;  3C9E A;  1AYW A;  2YJ2 A;  1PPD A;  2PBH A;  4CDE B;  4Q8H A;  2DCD A;  2YJB A;  3PW3 A;  3BCN A;  2HHN A;  5EF4 A;  1EF7 A;  3M99 A;  4AXM A;  1PPP A;  4P6E A;  3CH2 X;  1AU3 A;  1M6D A;  2R9F A;  1GEC E;  1KHQ A;  4YVA A;  4FJC A;  3F5V A;  2E02 A;  1AYU A;  4Q8G A;  4DMY A;  3H89 A;  5EGW A;  1SP4 B;  2F7D A;  1EWM A;  9PAP A;  4QRX A;  1X9Y A;  1XKG A;  1ITO A;  3OF8 A;  2H7J A;  1CTE A;  3QJ3 A;  4HWY A;  1DEU A;  5A24 A;  4N4Z A;  2NQA A;  5FPW A;  2GFO A;  4YYQ A;  4BS5 A;  2DCA A;  2JQF R;  1CV8 A;  2XU1 A;  2VHS A;  3KWB X;  1AU4 A;  3LXS A;  3N4C A;  4KLB A;  2DC7 A;  3CBJ A;  3HWN A;  2FUD A;  2FTD A;  2DJG B;  2E01 A;  2NQG A;  2FRA A;  2NQI A;  1AYV A;  1BQI A;  3H8C A;  1ATK A;  3AI8 A;  4PP2 E;  2G7Y A;  3HHI A;  1YT7 A;  1PPN A;  1MIR A;  3IV2 A;  3U8E A;  2R6N A;  3WXF A;  2AUX A;  1EWP A;  1U9W A;  2HH5 A;  1IWD A;  2DZY A;  2P0R A;  2C0Y A;  3IOQ A;  4X6I A;  3OIS A;  4DMX A;  1SNK A;  3BPF A;  4P6G A;  3QSD A;  3D6S A;  1MDW A;  3O1G A;  3V6E A;  1ME4 A;  3HD3 A;  2R9O A;  2HXZ A;  3MTN A;  1PXV A;  1Y08 A;  1KFX L;  4MZO A;  2BDL A;  1ME3 A;  3KX1 A;  4PP1 A;  1NB5 A;  2Y6E A;  3N3G A;  1F29 A;  1AU0 A;  4QBB A;  3LFY A;  5CHV A;  1MEG A;  3CBK A;  4YYW A;  3RVX A;  4W4U A;  4X6J A;  4XR7 A;  5CVN B;  1THE A;  4XUI A;  3S3R A;  1Q6K A;  1STF E;  8PCH A;  1VSN A;  1KXR A;  3OVX A;  3K8U A;  3IEJ A;  2FQ9 A;  3PDF A;  3I3T A;  1EWO A;  4X6H A;  2G8E A;  1U9Q X;  3P5X A;  3O0U A;  1QXP A;  2IBI A;  1YK7 A;  7PCK A;  4QH6 A;  4BSQ A;  3BOW A;  4MZS A;  1AU2 A;  5J94 A;  4FIP A;  1A6R A;  1GMY A;  2WBF X;  3K9M A;  4K7C A;  4YYR A;  1FH0 A;  1NPZ A;  3P5U A;  3V6C A;  3WXE A;  3MOR A;  2FT2 A;  3KFQ A;  2FRQ A;  2YJ8 A;  1YVB A;  1O0E A;  4RY2 A;  2R9M A;  2AS8 A;  4I04 A;  2NQD B;  5K16 A;  3E1Z B;  1NL6 A;  4OEL A;  3H7D A;  2DCB A;  1JQP A;  2F1G A;  1CSB B;  2PNS A;  2YJ9 A;  1KFU L;  2PRE A;  3QT4 A;  3PBH A;  2XU4 A;  5PAD A;  1MS6 A;  3CH3 X;  3K24 A;  3USV A;  3WXG A;  4I05 A;  1GCB A;  2AIM A;  1YK8 A;  2OZ2 A;  3KKU A;  3H6S A;  1VJV A;  3H8B A;  4YYS A; 
#chains in the Genus database with same CATH topology
 4G54 A;  2Y5B A;  1Y4H A;  1ICF A;  4CZW A;  2UZJ A;  2AYO A;  4QRV A;  3I06 A;  4RKX A;  2E03 A;  3KSE A;  2VHF A;  2O6X A;  2PAD A;  1U5I A;  2B1M A;  4ZUX U;  3S3Q A;  1QMY A;  5CVM A;  1PBH A;  3P5V A;  4CDC B;  2AU1 A;  3W30 A;  1MEM A;  3GCB A;  2DZZ A;  3RNV A;  4PI3 A;  1TU6 A;  3IMA A;  1CQD A;  1QOL A;  4OVZ B;  1PAD A;  1BY8 A;  2ARY A;  3W31 A;  2DCC A;  2DC8 A;  3P5W A;  3MP2 A;  4OEM A;  1POP A;  1F2B A;  1PE6 A;  1MHW A;  3N3K A;  4W5B A;  3NHE A;  2ATO A;  2FYE A;  4BQV A;  2DJF B;  3BPM A;  4D8B A;  2B1N A;  2E00 A;  2YJC A;  1CPJ A;  2AYN A;  4CDF B;  1CB5 A;  3ERV A;  4WUR A;  1NQC A;  4RF1 A;  2GHU A;  2G8J A;  2P7U A;  4CDD B;  4MM3 B;  6PAD A;  1NB3 A;  5CHT A;  2OUL A;  4BS6 A;  2CIO A;  3KWZ A;  1BP4 A;  3OF9 A;  3IUT A;  4RNA A;  3MHS A;  2HD5 A;  4AXL A;  1ZCM A;  3MHH A;  1DF0 A;  3ZUA A;  4YYV A;  5F02 A;  4YYU A;  4YV8 A;  3F75 A;  3PNR A;  1ZIV A;  1S4V A;  3RVV A;  3PHU A;  4QRG A;  4N8W A;  1UKF A;  5JA7 A;  3B79 A;  1CJL A;  3OVZ A;  2IPP B;  1CVZ A;  3RVW A;  2G6D A;  2OP3 A;  1TL9 A;  2ACT A;  2JQG R;  2AUZ A;  4GUA A;  4WA6 A;  1NLJ A;  1QDQ A;  1K3B B;  2BTW B;  4I07 A;  3KW9 A;  1U9X A;  1TLO A;  1CS8 A;  4W5C A;  1PIP A;  4N79 A;  2R9N A;  1PCI A;  5JH3 A;  1EWL A;  5CVO B;  2CB5 A;  2XU5 A;  1F2C A;  3IHP A;  2FO5 A;  1HUC B;  1BGO A;  1YZB A;  4PAD A;  2DC6 A;  3BC3 A;  2R9C A;  1GLO A;  1YAL A;  1PPO A;  4FK5 A;  4MSX A;  3TNX A;  3BWK A;  2XU3 A;  2JTC A;  1U9V A;  4BPV A;  2P86 A;  3HHA A;  1KHP A;  3DF0 A;  1AIM A;  2DC9 A;  2AVW A;  1F2A A;  2BDZ A;  1AEC A;  3C9E A;  5EZS A;  2J7Q A;  3O65 A;  1AYW A;  2YJ2 A;  2HWK A;  1PPD A;  2PBH A;  4CDE B;  4Q8H A;  2DCD A;  2YJB A;  3PW3 A;  4OW0 A;  3BCN A;  2HHN A;  5EF4 A;  5KO3 A;  1EF7 A;  3M99 A;  4AXM A;  1PPP A;  4P6E A;  3PT2 A;  3CH2 X;  3BB7 A;  1AU3 A;  1M6D A;  2R9F A;  3PRM A;  1GEC E;  1KHQ A;  4YVA A;  4FJC A;  3F5V A;  2E02 A;  1AYU A;  4Q8G A;  4DMY A;  2J7Q C;  3H89 A;  5EGW A;  4BOP A;  1SP4 B;  2F7D A;  1EWM A;  9PAP A;  4QRX A;  1X9Y A;  1XKG A;  1ITO A;  4ZTB A;  3OF8 A;  2H7J A;  1CTE A;  3QJ3 A;  4HWY A;  1DEU A;  5A24 A;  4N4Z A;  2NQA A;  2Z84 A;  5FPW A;  2GFO A;  4YYQ A;  3MJ5 A;  3MTV A;  3BY4 A;  3PHX A;  4BS5 A;  2DCA A;  2JQF R;  1CV8 A;  4R3D A;  2XU1 A;  4A5U A;  2VHS A;  4RF0 A;  3KWB X;  1AU4 A;  3LXS A;  3N4C A;  2AGA A;  4KLB A;  2DC7 A;  3CBJ A;  3HWN A;  2FUD A;  2FTD A;  2DJG B;  2E01 A;  2NQG A;  2FRA A;  2NQI A;  2DOS A;  1AYV A;  1BQI A;  3H8C A;  1ATK A;  3AI8 A;  4PP2 E;  2G7Y A;  3HHI A;  1YT7 A;  1PPN A;  1MIR A;  3IV2 A;  3U8E A;  2R6N A;  5EZQ A;  3WXF A;  4BOS A;  2AUX A;  1DKI A;  1EWP A;  1U9W A;  2HH5 A;  1IWD A;  2DZY A;  2P0R A;  4BOU A;  2C0Y A;  3IOQ A;  4X6I A;  3OIS A;  4DMX A;  1SNK A;  3BPF A;  4P6G A;  3QSD A;  3D6S A;  1MDW A;  3O1G A;  3V6E A;  1ME4 A;  3HD3 A;  2R9O A;  2HXZ A;  3MTN A;  1PXV A;  1Y08 A;  1KFX L;  4MZO A;  2BDL A;  1ME3 A;  3KX1 A;  4IP3 A;  4BOZ A;  4PP1 A;  1NB5 A;  2Y6E A;  5E6J A;  3N3G A;  1F29 A;  1AU0 A;  3TMP A;  3IFU A;  4HXD B;  4QBB A;  3LFY A;  4M0W A;  5CHV A;  1MEG A;  3PHW A;  3CBK A;  4YYW A;  4D8I A;  3RVX A;  4W4U A;  4X6J A;  4XR7 A;  5CVN B;  1THE A;  4XUI A;  3S3R A;  4IUM A;  2BU3 A;  1Q6K A;  1STF E;  4REZ A;  3ZNH A;  8PCH A;  3TRK A;  1VSN A;  1KXR A;  3OVX A;  3K8U A;  3IEJ A;  2FQ9 A;  3PDF A;  3I3T A;  1EWO A;  3C0R A;  4X6H A;  2G8E A;  1U9Q X;  3P5X A;  3O0U A;  1QXP A;  2IBI A;  1YK7 A;  7PCK A;  4QH6 A;  2BTW A;  4BSQ A;  3BOW A;  4MZS A;  1AU2 A;  4BOQ A;  5J94 A;  4FIP A;  1A6R A;  1GMY A;  2WBF X;  3K9M A;  4K7C A;  4P16 A;  4YYR A;  1FH0 A;  1NPZ A;  3P5U A;  3V6C A;  3WXE A;  3MOR A;  2FT2 A;  3KFQ A;  4D8E A;  3BBA A;  2FRQ A;  2YJ8 A;  1YVB A;  1O0E A;  4RY2 A;  1PVJ A;  2R9M A;  2AS8 A;  4I04 A;  3OQC A;  2NQD B;  3PRP A;  2JRI A;  5K16 A;  3PSE A;  4XZX A;  2FE8 A;  3E1Z B;  4MI7 A;  1NL6 A;  4OEL A;  3H7D A;  2DCB A;  1JQP A;  2F1G A;  1CSB B;  2PNS A;  2YJ9 A;  4OVZ A;  1KFU L;  2PRE A;  5JZE A;  3E9S A;  3QT4 A;  3PBH A;  2XU4 A;  5PAD A;  1MS6 A;  3CH3 X;  3K24 A;  3USV A;  3WXG A;  4I05 A;  1GCB A;  2AIM A;  1YK8 A;  4PT5 A;  2OZ2 A;  3KKU A;  3H6S A;  3B21 A;  1VJV A;  3H8B A;  4YYS A; 
#chains in the Genus database with same CATH homology
 4G54 A;  2Y5B A;  1Y4H A;  1ICF A;  4CZW A;  2AYO A;  4QRV A;  3I06 A;  2E03 A;  3KSE A;  2VHF A;  2O6X A;  2PAD A;  1U5I A;  2B1M A;  4ZUX U;  3S3Q A;  1QMY A;  5CVM A;  1PBH A;  3P5V A;  4CDC B;  2AU1 A;  1MEM A;  3GCB A;  2DZZ A;  4PI3 A;  1TU6 A;  3IMA A;  1CQD A;  1QOL A;  1PAD A;  1BY8 A;  2ARY A;  2DCC A;  2DC8 A;  3P5W A;  4OEM A;  1POP A;  1F2B A;  1PE6 A;  1MHW A;  3N3K A;  4W5B A;  3NHE A;  2ATO A;  2FYE A;  4BQV A;  2DJF B;  3BPM A;  2B1N A;  2E00 A;  2YJC A;  1CPJ A;  2AYN A;  4CDF B;  1CB5 A;  3ERV A;  1NQC A;  2GHU A;  2G8J A;  2P7U A;  4CDD B;  6PAD A;  1NB3 A;  5CHT A;  1GX3 A;  2OUL A;  4BS6 A;  2CIO A;  3KWZ A;  1BP4 A;  3OF9 A;  3IUT A;  3MHS A;  2HD5 A;  1W4T A;  4AXL A;  1ZCM A;  3MHH A;  1DF0 A;  3ZUA A;  4YYV A;  5F02 A;  4YYU A;  4YV8 A;  3F75 A;  3PNR A;  1ZIV A;  1S4V A;  3RVV A;  4QRG A;  4N8W A;  5JA7 A;  3B79 A;  1CJL A;  3OVZ A;  2IPP B;  1CVZ A;  3RVW A;  2G6D A;  2OP3 A;  1TL9 A;  2ACT A;  2JQG R;  2AUZ A;  4WA6 A;  1NLJ A;  1QDQ A;  1K3B B;  4I07 A;  3KW9 A;  1U9X A;  1TLO A;  1CS8 A;  4W5C A;  1PIP A;  4N79 A;  2R9N A;  1PCI A;  5JH3 A;  1EWL A;  5CVO B;  2CB5 A;  2XU5 A;  1F2C A;  3IHP A;  2FO5 A;  1E2T A;  1HUC B;  1BGO A;  4PAD A;  2DC6 A;  3BC3 A;  2R9C A;  1GLO A;  1YAL A;  1PPO A;  4FK5 A;  4MSX A;  3TNX A;  3BWK A;  2XU3 A;  4BPV A;  1U9V A;  1W5R A;  2P86 A;  3HHA A;  1KHP A;  3DF0 A;  1AIM A;  2DC9 A;  2AVW A;  1F2A A;  2BDZ A;  1AEC A;  3C9E A;  1AYW A;  2YJ2 A;  1PPD A;  2PBH A;  4CDE B;  4Q8H A;  2DCD A;  2YJB A;  3PW3 A;  3BCN A;  2HHN A;  3D9W A;  2VFC A;  5EF4 A;  1EF7 A;  3M99 A;  4AXM A;  1PPP A;  4P6E A;  3CH2 X;  1AU3 A;  1M6D A;  2R9F A;  1GEC E;  1KHQ A;  4YVA A;  4FJC A;  3F5V A;  2E02 A;  1AYU A;  4Q8G A;  4DMY A;  3H89 A;  5EGW A;  1SP4 B;  2F7D A;  1EWM A;  9PAP A;  4QRX A;  1X9Y A;  1XKG A;  1ITO A;  3OF8 A;  2H7J A;  1CTE A;  3QJ3 A;  4HWY A;  1DEU A;  5A24 A;  4N4Z A;  2NQA A;  5FPW A;  2GFO A;  4YYQ A;  4BS5 A;  2DCA A;  2JQF R;  1CV8 A;  2XU1 A;  2VHS A;  3KWB X;  1AU4 A;  3LXS A;  3N4C A;  4KLB A;  2DC7 A;  3CBJ A;  3HWN A;  2FUD A;  2FTD A;  4BGF A;  2DJG B;  2E01 A;  2NQG A;  2FRA A;  2NQI A;  1AYV A;  1BQI A;  3H8C A;  1ATK A;  3AI8 A;  4PP2 E;  2G7Y A;  3HHI A;  1YT7 A;  1PPN A;  1MIR A;  3IV2 A;  3U8E A;  2R6N A;  3WXF A;  2AUX A;  1EWP A;  1U9W A;  2HH5 A;  1IWD A;  2DZY A;  2P0R A;  4B55 A;  2C0Y A;  3IOQ A;  4X6I A;  3OIS A;  4DMX A;  1SNK A;  3BPF A;  4P6G A;  3QSD A;  3D6S A;  1MDW A;  3O1G A;  3V6E A;  1ME4 A;  3HD3 A;  2R9O A;  2HXZ A;  3MTN A;  1PXV A;  1Y08 A;  1KFX L;  4MZO A;  2BDL A;  1ME3 A;  3KX1 A;  4PP1 A;  1NB5 A;  2Y6E A;  3N3G A;  1F29 A;  1AU0 A;  4QBB A;  3LFY A;  4C5P A;  5CHV A;  1MEG A;  3CBK A;  4YYW A;  3RVX A;  4W4U A;  4X6J A;  4NV8 A;  4XR7 A;  1THE A;  5CVN B;  4XUI A;  3S3R A;  1Q6K A;  1STF E;  8PCH A;  1VSN A;  1KXR A;  3OVX A;  3K8U A;  3IEJ A;  2FQ9 A;  3PDF A;  3I3T A;  1EWO A;  4X6H A;  2G8E A;  1U9Q X;  3P5X A;  3O0U A;  1QXP A;  2IBI A;  1YK7 A;  7PCK A;  4QH6 A;  2VFB A;  4BSQ A;  3BOW A;  4MZS A;  1AU2 A;  5J94 A;  4FIP A;  1A6R A;  1GMY A;  2WBF X;  3K9M A;  4K7C A;  4YYR A;  1FH0 A;  1NPZ A;  3P5U A;  3V6C A;  3WXE A;  3MOR A;  2FT2 A;  3KFQ A;  2FRQ A;  2YJ8 A;  1YVB A;  1O0E A;  4RY2 A;  2R9M A;  2AS8 A;  4I04 A;  2NQD B;  5K16 A;  1W6F A;  3E1Z B;  1NL6 A;  4OEL A;  3H7D A;  2DCB A;  1JQP A;  2F1G A;  1CSB B;  2PNS A;  2YJ9 A;  1KFU L;  2PRE A;  3QT4 A;  3PBH A;  2XU4 A;  5PAD A;  4GUZ A;  1MS6 A;  3CH3 X;  3K24 A;  3USV A;  3WXG A;  2BSZ A;  4I05 A;  1GCB A;  2AIM A;  3LTW A;  1YK8 A;  4NV7 A;  2OZ2 A;  3KKU A;  3H6S A;  1VJV A;  3H8B A;  4YYS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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