3F75A

Activated toxoplasma gondii cathepsin l (tgcpl) in complex with its propeptide
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
223
structure length
223
Chain Sequence
VLPSELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDCSRAEGNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVPRRSEAAMKAALAKSPVSIAIEADQMPFQFYHEGVFDASCGTDLDHGVLLVGYGTDKESKKDFWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl.
pubmed doi rcsb
molecule tags Hydrolase
source organism Toxoplasma gondii
molecule keywords Cathepsin L Protease
total genus 67
structure length 223
sequence length 223
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2008-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3f75A00
1YVBA 3K9MA 1QMYA 2NQAA 1PE6A 4FJCA 2G6DA 1AIMA 1AECA 4DMYA 2R9FA 2XU5A 3F5VA 1EWPA 2PBHA 9PAPA 3DF0A 1S4VA 1THEA 4CDDB 3F75A 3IEJA 4PADA 2AVWA 1NL6A 4MZSA 1PBHA 3CBKA 1VJVA 2NQIA 1EWOA 2P7UA 4P6EA 4ZUXU 1QDQA 2DC8A 1K3BB 1U5IA 3PBHA 3E1ZB 1BP4A 2WBFX 1U9QX 4WA6A 1AU3A 3H8BA 1EF7A 2AUXA 1AU4A 4BS6A 3OISA 1MHWA 3B79A 2F7DA 2FRQA 1EWLA 1POPA 4BPVA 1CS8A 2AUZA 4YYSA 4BS5A 1O0EA 3H8CA 4I04A 3K24A 1PPOA 1U9VA 2H7JA 2DCBA 2P86A 3WXFA 3IMAA 2HD5A 2BDZA 4W5BA 5EGWA 1XKGA 1Y4HA 1GMYA 1DF0A 2VHSA 5JH3A 2R9MA 3BPFA 4DMXA 4Q8GA 2FO5A 3RVVA 2Y6EA 4P6GA 1KXRA 2HXZA 4YYVA 4OELA 2B1NA 3N4CA 1MDWA 3LFYA 2R9OA 4N79A 1PADA 1FH0A 2YJCA 3AI8A 2AS8A 2YJ9A 1X9YA 4PP1A 4PP2E 3KFQA 3O1GA 3P5XA 4MZOA 3OF9A 4YYRA 2FT2A 3D6SA 5F02A 3OVXA 1PPPA 1PCIA 2E00A 5FPWA 1CB5A 2DJFB 3KSEA 1GECE 3C9EA 4CDCB 5CVMA 3KKUA 3KW9A 4OEMA 4YYQA 3MHSA 3S3QA 3P5VA 2DJGB 3KX1A 3QT4A 2AU1A 1HUCB 1GLOA 4G54A 4YV8A 4YYWA 1Y08A 1NPZA 4CZWA 1ICFA 2DCDA 2AYNA 1AYVA 1CPJA 1NB3A 3WXGA 4QRXA 4N8WA 2FRAA 3RVWA 4QRGA 4RY2A 3GCBA 1AU0A 1TL9A 3USVA 2E03A 1IWDA 3N3KA 3BC3A 3MORA 3IHPA 1U9XA 3WXEA 1CSBB 2XU4A 1AYUA 2XU3A 2OULA 1TLOA 1KFXL 2IPPB 2F1GA 5CVNB 1TU6A 2R9CA 1NLJA 3PNRA 5PADA 1PXVA 3QJ3A 2G8JA 3H7DA 3U8EA 2JQGR 3TNXA 2NQDB 1A6RA 2DCCA 1NQCA 5J94A 5A24A 3H89A 4X6IA 2FQ9A 2BDLA 3MTNA 4AXMA 2PREA 1NB5A 2OZ2A 2YJ8A 1PIPA 3P5UA 2IBIA 5CVOB 3K8UA 3BWKA 2DC9A 1Q6KA 1F2AA 4QBBA 1PPDA 1MEGA 1CVZA 1M6DA 1KHPA 1SNKA 2YJ2A 3KWZA 4HWYA 2JQFR 4Q8HA 3PW3A 3CBJA 4I07A 2C0YA 2R6NA 2DCAA 6PADA 2NQGA 4W4UA 2DZYA 1KFUL 1ZCMA 2PNSA 2CIOA 4FIPA 1QXPA 4XR7A 1QOLA 1BGOA 3LXSA 1MIRA 3HWNA 3HHIA 3I06A 1VSNA 2DC7A 2YJBA 2OP3A 1YK7A 2O6XA 3OVZA 1SP4B 3NHEA 1ITOA 2HH5A 2G7YA 2GFOA 4MSXA 2DZZA 8PCHA 3BPMA 3QSDA 4FK5A 1CV8A 4CDFB 1ME3A 3CH3X 2ATOA 2CB5A 3S3RA 3ERVA 3M99A 4X6HA 4X6JA 5CHVA 1F2BA 3ZUAA 2AYOA 2FUDA 1YK8A 4PI3A 3CH2X 1CJLA 3P5WA 1STFE 3OF8A 2P0RA 1YALA 3IV2A 1U9WA 3KWBX 1BQIA 1CQDA 1ME4A 3RVXA 2VHFA 1JQPA 1KHQA 2DC6A 1ATKA 3BOWA 3I3TA 1EWMA 5CHTA 2ARYA 4KLBA 4W5CA 3H6SA 2B1MA 7PCKA 3BCNA 2E01A 4XUIA 4YYUA 4I05A 4K7CA 1F2CA 5EF4A 1PPNA 2R9NA 2XU1A 3HD3A 3V6EA 4QRVA 2PADA 2Y5BA 3O0UA 1CTEA 2FYEA 4BSQA 2GHUA 2HHNA 5K16A 1DEUA 4CDEB 1AU2A 1F29A 1AYWA 1MEMA 4QH6A 4AXLA 1GCBA 2FTDA 2G8EA 3IOQA 3MHHA 2E02A 3HHAA 3V6CA 4YVAA 4N4ZA 1ZIVA 5JA7A 1YT7A 3IUTA 3PDFA 2AIMA 3N3GA 1BY8A 2ACTA 1MS6A 4BQVA
chains in the Genus database with same CATH superfamily
1YVBA 3K9MA 1QMYA 2NQAA 1PE6A 4FJCA 2G6DA 1AIMA 1AECA 4DMYA 2R9FA 2XU5A 3F5VA 1EWPA 2PBHA 9PAPA 3DF0A 1S4VA 1THEA 4CDDB 3F75A 3IEJA 4PADA 2AVWA 1NL6A 4MZSA 4WURA 1PBHA 3CBKA 1VJVA 2NQIA 1EWOA 4OW0A 2P7UA 4P6EA 4ZUXU 1QDQA 2DC8A 1K3BB 1U5IA 4OVZB 3PBHA 3E1ZB 1BP4A 2WBFX 1U9QX 4WA6A 1AU3A 3H8BA 1EF7A 4IP3A 4D8BA 2AUXA 4OVZA 1AU4A 2Z84A 4BS6A 3OISA 1MHWA 3B79A 2HWKA 2F7DA 2FRQA 1EWLA 1POPA 4BPVA 1CS8A 2AUZA 3ZNHA 4BOSA 4YYSA 4BS5A 1O0EA 3H8CA 4I04A 3K24A 1PPOA 1U9VA 2H7JA 2DCBA 2P86A 3WXFA 3IMAA 3PHXA 2HD5A 3PRMA 2BDZA 4W5BA 5EGWA 1XKGA 3C0RA 1Y4HA 2BU3A 1GMYA 1DF0A 2VHSA 5JH3A 2R9MA 3BPFA 4DMXA 4Q8GA 2FO5A 3RVVA 2Y6EA 4P6GA 1KXRA 2HXZA 4YYVA 4OELA 2B1NA 3N4CA 1MDWA 3LFYA 2R9OA 4N79A 1UKFA 1PADA 1FH0A 2YJCA 3AI8A 2AS8A 2YJ9A 1X9YA 4PP1A 4PP2E 3KFQA 3O1GA 3P5XA 4MZOA 3OF9A 3PT2A 4YYRA 3BB7A 2FT2A 3D6SA 4RNAA 3PHWA 5F02A 4RF1A 4D8IA 3OVXA 3BBAA 5JZEA 1PPPA 1PCIA 2E00A 5FPWA 1CB5A 3RNVA 2DJFB 4BOQA 3KSEA 1GECE 3C9EA 3BY4A 4CDCB 5CVMA 3KKUA 3KW9A 4OEMA 4ZTBA 4YYQA 3MHSA 3S3QA 3P5VA 2DJGB 3KX1A 3QT4A 2AU1A 5KO3A 1HUCB 1GLOA 4G54A 4YV8A 4YYWA 1Y08A 1NPZA 4CZWA 1ICFA 2DCDA 2AYNA 1AYVA 1CPJA 1NB3A 3WXGA 4QRXA 4N8WA 2FRAA 3RVWA 3O65A 4QRGA 4RY2A 3W31A 3GCBA 1AU0A 1TL9A 3USVA 3TMPA 2E03A 1IWDA 3N3KA 4PT5A 3TRKA 3BC3A 3MORA 3IHPA 1U9XA 3WXEA 1CSBB 3MTVA 2XU4A 1AYUA 2XU3A 2OULA 1TLOA 1KFXL 2IPPB 2F1GA 5CVNB 1TU6A 4M0WA 2R9CA 1NLJA 3PNRA 5PADA 1PXVA 2UZJA 2AGAA 2BTWB 3QJ3A 2G8JA 3H7DA 3U8EA 2JQGR 3TNXA 2NQDB 1A6RA 2DCCA 1NQCA 5J94A 5A24A 3H89A 4X6IA 2FQ9A 4R3DA 2BDLA 3MTNA 2BTWA 4AXMA 4BOUA 5EZQA 2PREA 1NB5A 2OZ2A 2YJ8A 1PIPA 3PHUA 3P5UA 2IBIA 5CVOB 3K8UA 3BWKA 3IFUA 4P16A 2DC9A 1Q6KA 1F2AA 3OQCA 4QBBA 1DKIA 1PPDA 1MEGA 1CVZA 1M6DA 1KHPA 1SNKA 2YJ2A 3KWZA 4HWYA 4MM3B 2JQFR 4Q8HA 4XZXA 3PW3A 3CBJA 4I07A 3E9SA 3PRPA 2C0YA 2R6NA 2DCAA 6PADA 2NQGA 4W4UA 2DZYA 4REZA 1KFUL 1ZCMA 2PNSA 2CIOA 3B21A 4FIPA 1QXPA 4XR7A 1QOLA 1BGOA 3LXSA 1MIRA 1YZBA 3HWNA 3HHIA 3I06A 1VSNA 2YJBA 2DC7A 2DOSA 2OP3A 1YK7A 2O6XA 3OVZA 1SP4B 3NHEA 1ITOA 2HH5A 2G7YA 2GFOA 4MSXA 2DZZA 8PCHA 3MJ5A 3BPMA 3QSDA 4FK5A 1CV8A 4CDFB 1ME3A 3CH3X 2ATOA 1PVJA 2CB5A 3S3RA 3ERVA 3M99A 4RKXA 4X6HA 2JTCA 4X6JA 5CHVA 1F2BA 4GUAA 3ZUAA 2AYOA 2FUDA 2JRIA 5E6JA 1YK8A 4PI3A 3CH2X 1CJLA 2J7QC 3P5WA 1STFE 3OF8A 2P0RA 4HXDB 4BOZA 1YALA 3IV2A 1U9WA 3KWBX 1BQIA 1CQDA 1ME4A 4MI7A 3RVXA 2VHFA 1JQPA 1KHQA 2DC6A 4RF0A 1ATKA 3BOWA 3I3TA 1EWMA 5CHTA 2ARYA 3MP2A 4KLBA 3W30A 4W5CA 3H6SA 2B1MA 7PCKA 3BCNA 4D8EA 2E01A 4XUIA 4YYUA 4I05A 4K7CA 4A5UA 1F2CA 5EF4A 4BOPA 1PPNA 2R9NA 2FE8A 5EZSA 3HD3A 2J7QA 2XU1A 3V6EA 4QRVA 2PADA 2Y5BA 3O0UA 1CTEA 2FYEA 4BSQA 3PSEA 2GHUA 2HHNA 5K16A 1DEUA 4CDEB 1AU2A 1F29A 1AYWA 1MEMA 4QH6A 4AXLA 1GCBA 2FTDA 2G8EA 3IOQA 3MHHA 2E02A 3HHAA 3V6CA 4YVAA 4N4ZA 1ZIVA 5JA7A 1YT7A 3IUTA 3PDFA 2AIMA 3N3GA 1BY8A 4IUMA 2ACTA 1MS6A 4BQVA
chains in the Genus database with same CATH topology
1YVBA 3K9MA 1QMYA 2NQAA 1PE6A 4FJCA 2G6DA 1AIMA 1AECA 4DMYA 2R9FA 2XU5A 3F5VA 1EWPA 2PBHA 9PAPA 3DF0A 1S4VA 1THEA 4NV8A 4CDDB 3F75A 3IEJA 4PADA 2AVWA 1NL6A 4MZSA 1PBHA 3CBKA 1VJVA 2NQIA 1EWOA 2P7UA 4P6EA 4ZUXU 1QDQA 2DC8A 1K3BB 1U5IA 3PBHA 3E1ZB 1BP4A 2WBFX 1U9QX 4WA6A 1AU3A 3H8BA 1EF7A 2AUXA 1AU4A 4BS6A 3OISA 1MHWA 3B79A 2F7DA 2FRQA 1EWLA 1POPA 4BPVA 1CS8A 2AUZA 4YYSA 4BS5A 1O0EA 3H8CA 4I04A 3K24A 1E2TA 1PPOA 1U9VA 2H7JA 2DCBA 2P86A 3WXFA 3IMAA 2HD5A 2BDZA 4W5BA 5EGWA 1XKGA 1Y4HA 1GMYA 1DF0A 2VHSA 5JH3A 2R9MA 3BPFA 4DMXA 4Q8GA 2FO5A 3RVVA 2Y6EA 4P6GA 1KXRA 4BGFA 2HXZA 4YYVA 4OELA 2B1NA 3N4CA 1MDWA 3LFYA 2R9OA 4N79A 1PADA 1FH0A 2YJCA 3AI8A 2AS8A 2YJ9A 1X9YA 4PP1A 4PP2E 1W6FA 3KFQA 3O1GA 3P5XA 4MZOA 3OF9A 4YYRA 2FT2A 3D6SA 5F02A 3OVXA 1W4TA 1PPPA 1PCIA 4B55A 2E00A 5FPWA 1CB5A 2DJFB 3KSEA 1GECE 3C9EA 4CDCB 5CVMA 3KKUA 3KW9A 4OEMA 4NV7A 4YYQA 3MHSA 3S3QA 3P5VA 2DJGB 3D9WA 3KX1A 3QT4A 2AU1A 1HUCB 1GLOA 4G54A 4YV8A 4YYWA 1Y08A 1NPZA 4CZWA 1ICFA 2DCDA 2AYNA 1AYVA 1CPJA 1NB3A 3WXGA 4QRXA 4N8WA 2FRAA 3RVWA 1GX3A 4QRGA 4RY2A 3GCBA 1AU0A 1TL9A 3USVA 2E03A 1IWDA 3N3KA 3BC3A 3MORA 3IHPA 1U9XA 3WXEA 1CSBB 2XU4A 1AYUA 2XU3A 2OULA 1TLOA 1KFXL 2IPPB 2F1GA 5CVNB 1TU6A 2R9CA 1NLJA 3PNRA 5PADA 1PXVA 2VFBA 3QJ3A 2G8JA 3H7DA 3U8EA 2JQGR 3TNXA 2NQDB 1A6RA 2DCCA 1NQCA 5J94A 5A24A 3H89A 4X6IA 2FQ9A 2BDLA 3MTNA 4AXMA 2PREA 1NB5A 2OZ2A 3LTWA 2YJ8A 1PIPA 3P5UA 2IBIA 5CVOB 3K8UA 3BWKA 2DC9A 1Q6KA 1F2AA 4QBBA 1PPDA 1MEGA 1CVZA 1M6DA 1KHPA 1SNKA 2YJ2A 3KWZA 1W5RA 4HWYA 2JQFR 4Q8HA 4C5PA 3PW3A 3CBJA 4I07A 2C0YA 2R6NA 2DCAA 6PADA 2NQGA 4W4UA 2DZYA 1KFUL 1ZCMA 2PNSA 4GUZA 2CIOA 4FIPA 1QXPA 4XR7A 1QOLA 1BGOA 3LXSA 1MIRA 3HWNA 3HHIA 3I06A 1VSNA 2DC7A 2YJBA 2OP3A 1YK7A 2O6XA 3OVZA 1SP4B 3NHEA 1ITOA 2HH5A 2G7YA 2GFOA 4MSXA 2DZZA 8PCHA 3BPMA 3QSDA 4FK5A 1CV8A 4CDFB 1ME3A 3CH3X 2ATOA 2CB5A 3S3RA 3ERVA 3M99A 4X6HA 4X6JA 5CHVA 1F2BA 3ZUAA 2AYOA 2FUDA 1YK8A 4PI3A 3CH2X 1CJLA 3P5WA 1STFE 3OF8A 2P0RA 1YALA 3IV2A 1U9WA 3KWBX 1BQIA 1CQDA 1ME4A 3RVXA 2VHFA 1JQPA 1KHQA 2DC6A 1ATKA 3BOWA 3I3TA 1EWMA 5CHTA 2ARYA 4KLBA 4W5CA 3H6SA 2B1MA 7PCKA 3BCNA 2E01A 4XUIA 4YYUA 4I05A 4K7CA 1F2CA 5EF4A 1PPNA 2R9NA 2XU1A 3HD3A 3V6EA 4QRVA 2PADA 2Y5BA 3O0UA 1CTEA 2FYEA 4BSQA 2GHUA 2HHNA 5K16A 1DEUA 4CDEB 1AU2A 2BSZA 1F29A 1AYWA 1MEMA 4QH6A 4AXLA 1GCBA 2FTDA 2G8EA 3IOQA 3MHHA 2E02A 3HHAA 3V6CA 4YVAA 4N4ZA 2VFCA 1ZIVA 5JA7A 1YT7A 3IUTA 3PDFA 2AIMA 3N3GA 1BY8A 2ACTA 1MS6A 4BQVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YVB A;  3K9M A;  1QMY A;  2NQA A;  1PE6 A;  4FJC A;  2G6D A;  1AIM A;  1AEC A;  4DMY A;  2R9F A;  2XU5 A;  3F5V A;  1EWP A;  2PBH A;  9PAP A;  3DF0 A;  1S4V A;  1THE A;  4CDD B;  3F75 A;  3IEJ A;  4PAD A;  2AVW A;  1NL6 A;  4MZS A;  1PBH A;  3CBK A;  1VJV A;  2NQI A;  1EWO A;  2P7U A;  4P6E A;  4ZUX U;  1QDQ A;  2DC8 A;  1K3B B;  1U5I A;  3PBH A;  3E1Z B;  1BP4 A;  2WBF X;  1U9Q X;  4WA6 A;  1AU3 A;  3H8B A;  1EF7 A;  2AUX A;  1AU4 A;  4BS6 A;  3OIS A;  1MHW A;  3B79 A;  2F7D A;  2FRQ A;  1EWL A;  1POP A;  4BPV A;  1CS8 A;  2AUZ A;  4YYS A;  4BS5 A;  1O0E A;  3H8C A;  4I04 A;  3K24 A;  1PPO A;  1U9V A;  2H7J A;  2DCB A;  2P86 A;  3WXF A;  3IMA A;  2HD5 A;  2BDZ A;  4W5B A;  5EGW A;  1XKG A;  1Y4H A;  1GMY A;  1DF0 A;  2VHS A;  5JH3 A;  2R9M A;  3BPF A;  4DMX A;  4Q8G A;  2FO5 A;  3RVV A;  2Y6E A;  4P6G A;  1KXR A;  2HXZ A;  4YYV A;  4OEL A;  2B1N A;  3N4C A;  1MDW A;  3LFY A;  2R9O A;  4N79 A;  1PAD A;  1FH0 A;  2YJC A;  3AI8 A;  2AS8 A;  2YJ9 A;  1X9Y A;  4PP1 A;  4PP2 E;  3KFQ A;  3O1G A;  3P5X A;  4MZO A;  3OF9 A;  4YYR A;  2FT2 A;  3D6S A;  5F02 A;  3OVX A;  1PPP A;  1PCI A;  2E00 A;  5FPW A;  1CB5 A;  2DJF B;  3KSE A;  1GEC E;  3C9E A;  4CDC B;  5CVM A;  3KKU A;  3KW9 A;  4OEM A;  4YYQ A;  3MHS A;  3S3Q A;  3P5V A;  2DJG B;  3KX1 A;  3QT4 A;  2AU1 A;  1HUC B;  1GLO A;  4G54 A;  4YV8 A;  4YYW A;  1Y08 A;  1NPZ A;  4CZW A;  1ICF A;  2DCD A;  2AYN A;  1AYV A;  1CPJ A;  1NB3 A;  3WXG A;  4QRX A;  4N8W A;  2FRA A;  3RVW A;  4QRG A;  4RY2 A;  3GCB A;  1AU0 A;  1TL9 A;  3USV A;  2E03 A;  1IWD A;  3N3K A;  3BC3 A;  3MOR A;  3IHP A;  1U9X A;  3WXE A;  1CSB B;  2XU4 A;  1AYU A;  2XU3 A;  2OUL A;  1TLO A;  1KFX L;  2IPP B;  2F1G A;  5CVN B;  1TU6 A;  2R9C A;  1NLJ A;  3PNR A;  5PAD A;  1PXV A;  3QJ3 A;  2G8J A;  3H7D A;  3U8E A;  2JQG R;  3TNX A;  2NQD B;  1A6R A;  2DCC A;  1NQC A;  5J94 A;  5A24 A;  3H89 A;  4X6I A;  2FQ9 A;  2BDL A;  3MTN A;  4AXM A;  2PRE A;  1NB5 A;  2OZ2 A;  2YJ8 A;  1PIP A;  3P5U A;  2IBI A;  5CVO B;  3K8U A;  3BWK A;  2DC9 A;  1Q6K A;  1F2A A;  4QBB A;  1PPD A;  1MEG A;  1CVZ A;  1M6D A;  1KHP A;  1SNK A;  2YJ2 A;  3KWZ A;  4HWY A;  2JQF R;  4Q8H A;  3PW3 A;  3CBJ A;  4I07 A;  2C0Y A;  2R6N A;  2DCA A;  6PAD A;  2NQG A;  4W4U A;  2DZY A;  1KFU L;  1ZCM A;  2PNS A;  2CIO A;  4FIP A;  1QXP A;  4XR7 A;  1QOL A;  1BGO A;  3LXS A;  1MIR A;  3HWN A;  3HHI A;  3I06 A;  1VSN A;  2DC7 A;  2YJB A;  2OP3 A;  1YK7 A;  2O6X A;  3OVZ A;  1SP4 B;  3NHE A;  1ITO A;  2HH5 A;  2G7Y A;  2GFO A;  4MSX A;  2DZZ A;  8PCH A;  3BPM A;  3QSD A;  4FK5 A;  1CV8 A;  4CDF B;  1ME3 A;  3CH3 X;  2ATO A;  2CB5 A;  3S3R A;  3ERV A;  3M99 A;  4X6H A;  4X6J A;  5CHV A;  1F2B A;  3ZUA A;  2AYO A;  2FUD A;  1YK8 A;  4PI3 A;  3CH2 X;  1CJL A;  3P5W A;  1STF E;  3OF8 A;  2P0R A;  1YAL A;  3IV2 A;  1U9W A;  3KWB X;  1BQI A;  1CQD A;  1ME4 A;  3RVX A;  2VHF A;  1JQP A;  1KHQ A;  2DC6 A;  1ATK A;  3BOW A;  3I3T A;  1EWM A;  5CHT A;  2ARY A;  4KLB A;  4W5C A;  3H6S A;  2B1M A;  7PCK A;  3BCN A;  2E01 A;  4XUI A;  4YYU A;  4I05 A;  4K7C A;  1F2C A;  5EF4 A;  1PPN A;  2R9N A;  2XU1 A;  3HD3 A;  3V6E A;  4QRV A;  2PAD A;  2Y5B A;  3O0U A;  1CTE A;  2FYE A;  4BSQ A;  2GHU A;  2HHN A;  5K16 A;  1DEU A;  4CDE B;  1AU2 A;  1F29 A;  1AYW A;  1MEM A;  4QH6 A;  4AXL A;  1GCB A;  2FTD A;  2G8E A;  3IOQ A;  3MHH A;  2E02 A;  3HHA A;  3V6C A;  4YVA A;  4N4Z A;  1ZIV A;  5JA7 A;  1YT7 A;  3IUT A;  3PDF A;  2AIM A;  3N3G A;  1BY8 A;  2ACT A;  1MS6 A;  4BQV A; 
#chains in the Genus database with same CATH topology
 1YVB A;  3K9M A;  1QMY A;  2NQA A;  1PE6 A;  4FJC A;  2G6D A;  1AIM A;  1AEC A;  4DMY A;  2R9F A;  2XU5 A;  3F5V A;  1EWP A;  2PBH A;  9PAP A;  3DF0 A;  1S4V A;  1THE A;  4CDD B;  3F75 A;  3IEJ A;  4PAD A;  2AVW A;  1NL6 A;  4MZS A;  4WUR A;  1PBH A;  3CBK A;  1VJV A;  2NQI A;  1EWO A;  4OW0 A;  2P7U A;  4P6E A;  4ZUX U;  1QDQ A;  2DC8 A;  1K3B B;  1U5I A;  4OVZ B;  3PBH A;  3E1Z B;  1BP4 A;  2WBF X;  1U9Q X;  4WA6 A;  1AU3 A;  3H8B A;  1EF7 A;  4IP3 A;  4D8B A;  2AUX A;  4OVZ A;  1AU4 A;  2Z84 A;  4BS6 A;  3OIS A;  1MHW A;  3B79 A;  2HWK A;  2F7D A;  2FRQ A;  1EWL A;  1POP A;  4BPV A;  1CS8 A;  2AUZ A;  3ZNH A;  4BOS A;  4YYS A;  4BS5 A;  1O0E A;  3H8C A;  4I04 A;  3K24 A;  1PPO A;  1U9V A;  2H7J A;  2DCB A;  2P86 A;  3WXF A;  3IMA A;  3PHX A;  2HD5 A;  3PRM A;  2BDZ A;  4W5B A;  5EGW A;  1XKG A;  3C0R A;  1Y4H A;  2BU3 A;  1GMY A;  1DF0 A;  2VHS A;  5JH3 A;  2R9M A;  3BPF A;  4DMX A;  4Q8G A;  2FO5 A;  3RVV A;  2Y6E A;  4P6G A;  1KXR A;  2HXZ A;  4YYV A;  4OEL A;  2B1N A;  3N4C A;  1MDW A;  3LFY A;  2R9O A;  4N79 A;  1UKF A;  1PAD A;  1FH0 A;  2YJC A;  3AI8 A;  2AS8 A;  2YJ9 A;  1X9Y A;  4PP1 A;  4PP2 E;  3KFQ A;  3O1G A;  3P5X A;  4MZO A;  3OF9 A;  3PT2 A;  4YYR A;  3BB7 A;  2FT2 A;  3D6S A;  4RNA A;  3PHW A;  5F02 A;  4RF1 A;  4D8I A;  3OVX A;  3BBA A;  5JZE A;  1PPP A;  1PCI A;  2E00 A;  5FPW A;  1CB5 A;  3RNV A;  2DJF B;  4BOQ A;  3KSE A;  1GEC E;  3C9E A;  3BY4 A;  4CDC B;  5CVM A;  3KKU A;  3KW9 A;  4OEM A;  4ZTB A;  4YYQ A;  3MHS A;  3S3Q A;  3P5V A;  2DJG B;  3KX1 A;  3QT4 A;  2AU1 A;  5KO3 A;  1HUC B;  1GLO A;  4G54 A;  4YV8 A;  4YYW A;  1Y08 A;  1NPZ A;  4CZW A;  1ICF A;  2DCD A;  2AYN A;  1AYV A;  1CPJ A;  1NB3 A;  3WXG A;  4QRX A;  4N8W A;  2FRA A;  3RVW A;  3O65 A;  4QRG A;  4RY2 A;  3W31 A;  3GCB A;  1AU0 A;  1TL9 A;  3USV A;  3TMP A;  2E03 A;  1IWD A;  3N3K A;  4PT5 A;  3TRK A;  3BC3 A;  3MOR A;  3IHP A;  1U9X A;  3WXE A;  1CSB B;  3MTV A;  2XU4 A;  1AYU A;  2XU3 A;  2OUL A;  1TLO A;  1KFX L;  2IPP B;  2F1G A;  5CVN B;  1TU6 A;  4M0W A;  2R9C A;  1NLJ A;  3PNR A;  5PAD A;  1PXV A;  2UZJ A;  2AGA A;  2BTW B;  3QJ3 A;  2G8J A;  3H7D A;  3U8E A;  2JQG R;  3TNX A;  2NQD B;  1A6R A;  2DCC A;  1NQC A;  5J94 A;  5A24 A;  3H89 A;  4X6I A;  2FQ9 A;  4R3D A;  2BDL A;  3MTN A;  2BTW A;  4AXM A;  4BOU A;  5EZQ A;  2PRE A;  1NB5 A;  2OZ2 A;  2YJ8 A;  1PIP A;  3PHU A;  3P5U A;  2IBI A;  5CVO B;  3K8U A;  3BWK A;  3IFU A;  4P16 A;  2DC9 A;  1Q6K A;  1F2A A;  3OQC A;  4QBB A;  1DKI A;  1PPD A;  1MEG A;  1CVZ A;  1M6D A;  1KHP A;  1SNK A;  2YJ2 A;  3KWZ A;  4HWY A;  4MM3 B;  2JQF R;  4Q8H A;  4XZX A;  3PW3 A;  3CBJ A;  4I07 A;  3E9S A;  3PRP A;  2C0Y A;  2R6N A;  2DCA A;  6PAD A;  2NQG A;  4W4U A;  2DZY A;  4REZ A;  1KFU L;  1ZCM A;  2PNS A;  2CIO A;  3B21 A;  4FIP A;  1QXP A;  4XR7 A;  1QOL A;  1BGO A;  3LXS A;  1MIR A;  1YZB A;  3HWN A;  3HHI A;  3I06 A;  1VSN A;  2YJB A;  2DC7 A;  2DOS A;  2OP3 A;  1YK7 A;  2O6X A;  3OVZ A;  1SP4 B;  3NHE A;  1ITO A;  2HH5 A;  2G7Y A;  2GFO A;  4MSX A;  2DZZ A;  8PCH A;  3MJ5 A;  3BPM A;  3QSD A;  4FK5 A;  1CV8 A;  4CDF B;  1ME3 A;  3CH3 X;  2ATO A;  1PVJ A;  2CB5 A;  3S3R A;  3ERV A;  3M99 A;  4RKX A;  4X6H A;  2JTC A;  4X6J A;  5CHV A;  1F2B A;  4GUA A;  3ZUA A;  2AYO A;  2FUD A;  2JRI A;  5E6J A;  1YK8 A;  4PI3 A;  3CH2 X;  1CJL A;  2J7Q C;  3P5W A;  1STF E;  3OF8 A;  2P0R A;  4HXD B;  4BOZ A;  1YAL A;  3IV2 A;  1U9W A;  3KWB X;  1BQI A;  1CQD A;  1ME4 A;  4MI7 A;  3RVX A;  2VHF A;  1JQP A;  1KHQ A;  2DC6 A;  4RF0 A;  1ATK A;  3BOW A;  3I3T A;  1EWM A;  5CHT A;  2ARY A;  3MP2 A;  4KLB A;  3W30 A;  4W5C A;  3H6S A;  2B1M A;  7PCK A;  3BCN A;  4D8E A;  2E01 A;  4XUI A;  4YYU A;  4I05 A;  4K7C A;  4A5U A;  1F2C A;  5EF4 A;  4BOP A;  1PPN A;  2R9N A;  2FE8 A;  5EZS A;  3HD3 A;  2J7Q A;  2XU1 A;  3V6E A;  4QRV A;  2PAD A;  2Y5B A;  3O0U A;  1CTE A;  2FYE A;  4BSQ A;  3PSE A;  2GHU A;  2HHN A;  5K16 A;  1DEU A;  4CDE B;  1AU2 A;  1F29 A;  1AYW A;  1MEM A;  4QH6 A;  4AXL A;  1GCB A;  2FTD A;  2G8E A;  3IOQ A;  3MHH A;  2E02 A;  3HHA A;  3V6C A;  4YVA A;  4N4Z A;  1ZIV A;  5JA7 A;  1YT7 A;  3IUT A;  3PDF A;  2AIM A;  3N3G A;  1BY8 A;  4IUM A;  2ACT A;  1MS6 A;  4BQV A; 
#chains in the Genus database with same CATH homology
 1YVB A;  3K9M A;  1QMY A;  2NQA A;  1PE6 A;  4FJC A;  2G6D A;  1AIM A;  1AEC A;  4DMY A;  2R9F A;  2XU5 A;  3F5V A;  1EWP A;  2PBH A;  9PAP A;  3DF0 A;  1S4V A;  1THE A;  4NV8 A;  4CDD B;  3F75 A;  3IEJ A;  4PAD A;  2AVW A;  1NL6 A;  4MZS A;  1PBH A;  3CBK A;  1VJV A;  2NQI A;  1EWO A;  2P7U A;  4P6E A;  4ZUX U;  1QDQ A;  2DC8 A;  1K3B B;  1U5I A;  3PBH A;  3E1Z B;  1BP4 A;  2WBF X;  1U9Q X;  4WA6 A;  1AU3 A;  3H8B A;  1EF7 A;  2AUX A;  1AU4 A;  4BS6 A;  3OIS A;  1MHW A;  3B79 A;  2F7D A;  2FRQ A;  1EWL A;  1POP A;  4BPV A;  1CS8 A;  2AUZ A;  4YYS A;  4BS5 A;  1O0E A;  3H8C A;  4I04 A;  3K24 A;  1E2T A;  1PPO A;  1U9V A;  2H7J A;  2DCB A;  2P86 A;  3WXF A;  3IMA A;  2HD5 A;  2BDZ A;  4W5B A;  5EGW A;  1XKG A;  1Y4H A;  1GMY A;  1DF0 A;  2VHS A;  5JH3 A;  2R9M A;  3BPF A;  4DMX A;  4Q8G A;  2FO5 A;  3RVV A;  2Y6E A;  4P6G A;  1KXR A;  4BGF A;  2HXZ A;  4YYV A;  4OEL A;  2B1N A;  3N4C A;  1MDW A;  3LFY A;  2R9O A;  4N79 A;  1PAD A;  1FH0 A;  2YJC A;  3AI8 A;  2AS8 A;  2YJ9 A;  1X9Y A;  4PP1 A;  4PP2 E;  1W6F A;  3KFQ A;  3O1G A;  3P5X A;  4MZO A;  3OF9 A;  4YYR A;  2FT2 A;  3D6S A;  5F02 A;  3OVX A;  1W4T A;  1PPP A;  1PCI A;  4B55 A;  2E00 A;  5FPW A;  1CB5 A;  2DJF B;  3KSE A;  1GEC E;  3C9E A;  4CDC B;  5CVM A;  3KKU A;  3KW9 A;  4OEM A;  4NV7 A;  4YYQ A;  3MHS A;  3S3Q A;  3P5V A;  2DJG B;  3D9W A;  3KX1 A;  3QT4 A;  2AU1 A;  1HUC B;  1GLO A;  4G54 A;  4YV8 A;  4YYW A;  1Y08 A;  1NPZ A;  4CZW A;  1ICF A;  2DCD A;  2AYN A;  1AYV A;  1CPJ A;  1NB3 A;  3WXG A;  4QRX A;  4N8W A;  2FRA A;  3RVW A;  1GX3 A;  4QRG A;  4RY2 A;  3GCB A;  1AU0 A;  1TL9 A;  3USV A;  2E03 A;  1IWD A;  3N3K A;  3BC3 A;  3MOR A;  3IHP A;  1U9X A;  3WXE A;  1CSB B;  2XU4 A;  1AYU A;  2XU3 A;  2OUL A;  1TLO A;  1KFX L;  2IPP B;  2F1G A;  5CVN B;  1TU6 A;  2R9C A;  1NLJ A;  3PNR A;  5PAD A;  1PXV A;  2VFB A;  3QJ3 A;  2G8J A;  3H7D A;  3U8E A;  2JQG R;  3TNX A;  2NQD B;  1A6R A;  2DCC A;  1NQC A;  5J94 A;  5A24 A;  3H89 A;  4X6I A;  2FQ9 A;  2BDL A;  3MTN A;  4AXM A;  2PRE A;  1NB5 A;  2OZ2 A;  3LTW A;  2YJ8 A;  1PIP A;  3P5U A;  2IBI A;  5CVO B;  3K8U A;  3BWK A;  2DC9 A;  1Q6K A;  1F2A A;  4QBB A;  1PPD A;  1MEG A;  1CVZ A;  1M6D A;  1KHP A;  1SNK A;  2YJ2 A;  3KWZ A;  1W5R A;  4HWY A;  2JQF R;  4Q8H A;  4C5P A;  3PW3 A;  3CBJ A;  4I07 A;  2C0Y A;  2R6N A;  2DCA A;  6PAD A;  2NQG A;  4W4U A;  2DZY A;  1KFU L;  1ZCM A;  2PNS A;  4GUZ A;  2CIO A;  4FIP A;  1QXP A;  4XR7 A;  1QOL A;  1BGO A;  3LXS A;  1MIR A;  3HWN A;  3HHI A;  3I06 A;  1VSN A;  2DC7 A;  2YJB A;  2OP3 A;  1YK7 A;  2O6X A;  3OVZ A;  1SP4 B;  3NHE A;  1ITO A;  2HH5 A;  2G7Y A;  2GFO A;  4MSX A;  2DZZ A;  8PCH A;  3BPM A;  3QSD A;  4FK5 A;  1CV8 A;  4CDF B;  1ME3 A;  3CH3 X;  2ATO A;  2CB5 A;  3S3R A;  3ERV A;  3M99 A;  4X6H A;  4X6J A;  5CHV A;  1F2B A;  3ZUA A;  2AYO A;  2FUD A;  1YK8 A;  4PI3 A;  3CH2 X;  1CJL A;  3P5W A;  1STF E;  3OF8 A;  2P0R A;  1YAL A;  3IV2 A;  1U9W A;  3KWB X;  1BQI A;  1CQD A;  1ME4 A;  3RVX A;  2VHF A;  1JQP A;  1KHQ A;  2DC6 A;  1ATK A;  3BOW A;  3I3T A;  1EWM A;  5CHT A;  2ARY A;  4KLB A;  4W5C A;  3H6S A;  2B1M A;  7PCK A;  3BCN A;  2E01 A;  4XUI A;  4YYU A;  4I05 A;  4K7C A;  1F2C A;  5EF4 A;  1PPN A;  2R9N A;  2XU1 A;  3HD3 A;  3V6E A;  4QRV A;  2PAD A;  2Y5B A;  3O0U A;  1CTE A;  2FYE A;  4BSQ A;  2GHU A;  2HHN A;  5K16 A;  1DEU A;  4CDE B;  1AU2 A;  2BSZ A;  1F29 A;  1AYW A;  1MEM A;  4QH6 A;  4AXL A;  1GCB A;  2FTD A;  2G8E A;  3IOQ A;  3MHH A;  2E02 A;  3HHA A;  3V6C A;  4YVA A;  4N4Z A;  2VFC A;  1ZIV A;  5JA7 A;  1YT7 A;  3IUT A;  3PDF A;  2AIM A;  3N3G A;  1BY8 A;  2ACT A;  1MS6 A;  4BQV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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