3H7DA

The crystal structure of the cathepsin k variant m5 in complex with chondroitin-4-sulfate
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
215
structure length
215
Chain Sequence
APDSVDYREKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGESKGNKHWIIKNSWGENWGMGGYIKMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-activity analysis of cathepsin K/chondroitin 4-sulfate interactions.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 69
structure length 215
sequence length 215
chains with identical sequence E
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2009-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3h7dA00
1EF7A 1EWMA 3GCBA 1DF0A 2DC8A 2DCDA 3OF9A 1ME3A 1ICFA 1NLJA 5EF4A 2IPPB 4YYWA 2ATOA 4MSXA 1AECA 1YVBA 3BOWA 2DC9A 2G6DA 1PPOA 2AYNA 1DEUA 3BWKA 2DZZA 2R9NA 3H6SA 4XR7A 4CDEB 4PI3A 3N4CA 3MHSA 4AXMA 2HXZA 4MZSA 1F2CA 4BS6A 2AVWA 3I06A 4I07A 1S4VA 1XKGA 1PE6A 4WA6A 2H7JA 2PNSA 2R9OA 1Y08A 1ITOA 2OZ2A 3MTNA 2FRAA 3E1ZB 3D6SA 1FH0A 1CJLA 2DC6A 2XU4A 3KWZA 3OVXA 3PNRA 1STFE 3H89A 1TL9A 4DMXA 4W4UA 1EWPA 1KHPA 2NQIA 3QSDA 2E01A 4I05A 4PADA 3P5VA 2YJ9A 1BQIA 2HHNA 5FPWA 3O1GA 4FIPA 3IOQA 3K24A 2R9MA 3K8UA 1QXPA 2HH5A 2YJBA 4X6HA 3O0UA 4QH6A 3TNXA 1SNKA 4W5BA 2YJ8A 4PP1A 2DZYA 3CH3X 3PDFA 3V6CA 2R9CA 2DCCA 4BSQA 1NB5A 3F5VA 2AIMA 1U9QX 1NL6A 3IV2A 3RVVA 3DF0A 3V6EA 3QJ3A 1ME4A 1GLOA 2G8EA 1QOLA 3M99A 2NQAA 2PADA 3MHHA 2OP3A 3HWNA 1M6DA 3P5XA 4QRXA 4XUIA 3P5WA 2B1NA 2FO5A 2F7DA 4PP2E 4Q8GA 3C9EA 1TLOA 4QRGA 1EWOA 4YYRA 2OULA 4RY2A 3S3RA 4OEMA 4BPVA 1CQDA 1EWLA 2E00A 1POPA 2F1GA 1PXVA 2ACTA 4KLBA 1K3BB 2DCBA 1MEMA 1GMYA 2B1MA 3OF8A 8PCHA 1F2BA 1AIMA 2NQGA 3USVA 1VSNA 4CZWA 1PCIA 4Q8HA 1O0EA 1PPDA 3IEJA 2FTDA 1ZCMA 2AYOA 1THEA 2WBFX 3N3GA 1TU6A 1F29A 5CHVA 1AU2A 2R6NA 3HHIA 2FUDA 2YJCA 3IMAA 1YT7A 2JQGR 3IUTA 3I3TA 4YYUA 1AU3A 4CDFB 1NPZA 4G54A 4QRVA 3KWBX 4OELA 1BGOA 3RVXA 5CVMA 4CDCB 1U9VA 2E02A 3NHEA 4YV8A 1YK7A 6PADA 1VJVA 1CTEA 4YYSA 2DC7A 3HHAA 5JA7A 2CB5A 1X9YA 3PW3A 3F75A 3PBHA 1CVZA 5EGWA 1PBHA 4YYVA 1SP4B 2GFOA 4FK5A 2E03A 2AS8A 3ERVA 1KFXL 3KX1A 2XU5A 5CHTA 3BC3A 1MDWA 1ZIVA 4DMYA 4HWYA 1AYUA 4I04A 2JQFR 1PADA 4X6JA 5CVNB 3KKUA 5JH3A 9PAPA 4N8WA 3WXFA 2DJGB 1AYVA 1CV8A 1AU4A 2AUZA 1F2AA 1U9XA 3ZUAA 4BS5A 2FRQA 1PPNA 1GCBA 3B79A 3CBJA 1AU0A 3MORA 2AU1A 4N79A 3KFQA 1U9WA 2DJFB 2BDZA 2VHSA 3H8BA 3CH2X 1MS6A 3WXGA 1BP4A 1KFUL 1NQCA 1YK8A 1MIRA 2NQDB 4YVAA 2R9FA 3QT4A 3S3QA 3K9MA 4W5CA 2G7YA 1PPPA 4P6GA 2P86A 3LFYA 1PIPA 1CS8A 5F02A 2FQ9A 1A6RA 2ARYA 5CVOB 1YALA 3IHPA 1QMYA 1Q6KA 2XU3A 3OVZA 4N4ZA 4YYQA 3CBKA 5A24A 1JQPA 1MEGA 3HD3A 2AUXA 2YJ2A 4MZOA 2C0YA 2P0RA 1U5IA 1QDQA 1CB5A 1IWDA 1AYWA 3U8EA 1CSBB 2G8JA 1HUCB 4K7CA 2VHFA 3RVWA 5K16A 4FJCA 4P6EA 2PBHA 4AXLA 3P5UA 5J94A 1Y4HA 2BDLA 2Y6EA 3BCNA 4QBBA 2P7UA 2HD5A 3WXEA 1BY8A 2O6XA 3N3KA 2DCAA 3H7DA 4X6IA 3BPMA 3BPFA 7PCKA 1CPJA 2FT2A 3AI8A 2GHUA 1GECE 4CDDB 2FYEA 3LXSA 3KW9A 2CIOA 3KSEA 1ATKA 4ZUXU 2XU1A 1KXRA 5PADA 2IBIA 2Y5BA 1MHWA 1NB3A 3OISA 4BQVA 1KHQA 2PREA 3H8CA
chains in the Genus database with same CATH superfamily
2HWKA 1EF7A 1EWMA 3GCBA 1DF0A 4OW0A 2DC8A 2DCDA 3PT2A 3OF9A 4A5UA 4BOUA 1ME3A 3OQCA 1ICFA 1NLJA 5EF4A 2IPPB 4YYWA 2ATOA 4MSXA 1AECA 1YVBA 3BOWA 2DC9A 2G6DA 5E6JA 1PPOA 2AYNA 2FE8A 1UKFA 1DEUA 3BWKA 2DZZA 2R9NA 3H6SA 4XR7A 4CDEB 4PI3A 3N4CA 3MHSA 4AXMA 2HXZA 4MZSA 1F2CA 4BS6A 4RKXA 2AVWA 3I06A 4I07A 1S4VA 1XKGA 1PE6A 4WA6A 2H7JA 2PNSA 2DOSA 5EZSA 2R9OA 1Y08A 1ITOA 2OZ2A 3MTNA 2FRAA 5KO3A 3E1ZB 3D6SA 1FH0A 1CJLA 2DC6A 2XU4A 3KWZA 3TMPA 3OVXA 3PNRA 1STFE 3H89A 1TL9A 4DMXA 4W4UA 1EWPA 1KHPA 2NQIA 3QSDA 2E01A 4I05A 4PADA 3P5VA 2YJ9A 1BQIA 2HHNA 5FPWA 3O1GA 4FIPA 4D8IA 3IOQA 4D8BA 3K24A 2R9MA 4RNAA 3K8UA 1QXPA 2HH5A 2YJBA 4X6HA 3O0UA 4QH6A 3TNXA 3W30A 3RNVA 1SNKA 4W5BA 2YJ8A 4PP1A 2DZYA 3CH3X 3PDFA 3V6CA 2R9CA 3BB7A 4PT5A 2DCCA 4BSQA 1NB5A 3PRPA 4BOSA 3F5VA 2AIMA 1U9QX 1NL6A 3IV2A 3RVVA 3DF0A 3V6EA 3QJ3A 1ME4A 1GLOA 2G8EA 1QOLA 2Z84A 3M99A 2NQAA 2PADA 4M0WA 3MHHA 2OP3A 4GUAA 3HWNA 1M6DA 3P5XA 3PHWA 4QRXA 4XUIA 2JTCA 3P5WA 2B1NA 2FO5A 2F7DA 4PP2E 4Q8GA 3C9EA 1TLOA 4QRGA 1EWOA 4YYRA 2OULA 4RY2A 3S3RA 4OEMA 4BPVA 1CQDA 1EWLA 2E00A 1POPA 2F1GA 1PXVA 2ACTA 4KLBA 1K3BB 2DCBA 2J7QA 1MEMA 1GMYA 2B1MA 3OF8A 8PCHA 1F2BA 1AIMA 2NQGA 3PRMA 3USVA 1VSNA 5EZQA 4CZWA 1PCIA 4Q8HA 1O0EA 1PPDA 3IEJA 4BOPA 2FTDA 1ZCMA 2AYOA 1THEA 2WBFX 3N3GA 1TU6A 1F29A 5CHVA 1AU2A 2R6NA 3HHIA 4REZA 2FUDA 2YJCA 3IMAA 1YT7A 2JQGR 3IUTA 3I3TA 4YYUA 1AU3A 4CDFB 1NPZA 4G54A 4QRVA 4ZTBA 3KWBX 4MM3B 4OELA 1BGOA 3RVXA 5CVMA 4CDCB 1U9VA 2E02A 3BBAA 3NHEA 4YV8A 5JZEA 1YK7A 6PADA 1VJVA 1CTEA 4YYSA 2DC7A 3HHAA 5JA7A 2CB5A 1DKIA 1X9YA 3PW3A 3F75A 3PBHA 1CVZA 5EGWA 1PBHA 4YYVA 1SP4B 2J7QC 2GFOA 4FK5A 4OVZA 3W31A 2E03A 2AS8A 4HXDB 3ERVA 3PHXA 3MJ5A 1KFXL 3KX1A 2JRIA 2XU5A 5CHTA 3BC3A 1MDWA 1ZIVA 4DMYA 4HWYA 1AYUA 4RF1A 4I04A 2JQFR 1PADA 4X6JA 5CVNB 3KKUA 5JH3A 9PAPA 4N8WA 3E9SA 4OVZB 3WXFA 2DJGB 3BY4A 3TRKA 1AYVA 1CV8A 1AU4A 1PVJA 2AUZA 1F2AA 1U9XA 3ZNHA 3ZUAA 4BS5A 2FRQA 4IUMA 1PPNA 1GCBA 3B79A 3CBJA 3PHUA 1AU0A 3MORA 2AU1A 4N79A 3KFQA 1U9WA 2DJFB 2BDZA 2VHSA 3H8BA 3CH2X 1MS6A 3WXGA 1BP4A 1KFUL 1NQCA 1YK8A 1MIRA 2NQDB 4YVAA 2R9FA 3QT4A 3S3QA 4BOZA 3K9MA 3IFUA 4W5CA 2G7YA 1PPPA 4P6GA 2P86A 2BTWA 3LFYA 1YZBA 1PIPA 1CS8A 5F02A 2FQ9A 1A6RA 2ARYA 4BOQA 5CVOB 1YALA 3IHPA 4D8EA 1QMYA 1Q6KA 2XU3A 2BTWB 3MP2A 3OVZA 4N4ZA 4YYQA 3CBKA 5A24A 1JQPA 3O65A 2BU3A 1MEGA 3HD3A 2AUXA 2YJ2A 4MZOA 2C0YA 2P0RA 1U5IA 1QDQA 1CB5A 1IWDA 2AGAA 1AYWA 3U8EA 1CSBB 2G8JA 1HUCB 4MI7A 4K7CA 2VHFA 3RVWA 5K16A 4IP3A 3B21A 2UZJA 4FJCA 4P6EA 2PBHA 4AXLA 3P5UA 5J94A 1Y4HA 3PSEA 2BDLA 2Y6EA 3BCNA 4QBBA 2P7UA 3MTVA 2HD5A 4R3DA 4XZXA 3WXEA 4P16A 1BY8A 2O6XA 3N3KA 2DCAA 3H7DA 4X6IA 3BPMA 3BPFA 7PCKA 3C0RA 1CPJA 2FT2A 3AI8A 2GHUA 1GECE 4CDDB 2FYEA 3LXSA 3KW9A 2CIOA 3KSEA 1ATKA 4ZUXU 2XU1A 1KXRA 5PADA 2IBIA 2Y5BA 1MHWA 4RF0A 1NB3A 3OISA 4BQVA 1KHQA 2PREA 4WURA 3H8CA
chains in the Genus database with same CATH topology
1EF7A 1EWMA 3GCBA 1DF0A 2DC8A 2DCDA 3OF9A 1ME3A 1ICFA 1NLJA 4BGFA 5EF4A 2IPPB 4YYWA 2ATOA 4MSXA 1AECA 3LTWA 1YVBA 3BOWA 2DC9A 2G6DA 1PPOA 2AYNA 1DEUA 3BWKA 2DZZA 2R9NA 3H6SA 4XR7A 4CDEB 4PI3A 3N4CA 3MHSA 4AXMA 2HXZA 4MZSA 1F2CA 4BS6A 2AVWA 3I06A 4I07A 1S4VA 1XKGA 1PE6A 4WA6A 2H7JA 2PNSA 2R9OA 1Y08A 1ITOA 2OZ2A 2VFCA 3MTNA 2FRAA 3E1ZB 3D6SA 1FH0A 1CJLA 2DC6A 2XU4A 3KWZA 3OVXA 3PNRA 1STFE 3H89A 1TL9A 4DMXA 4W4UA 1EWPA 1KHPA 2NQIA 3QSDA 2E01A 4I05A 4PADA 3P5VA 2YJ9A 1BQIA 2HHNA 5FPWA 3O1GA 4FIPA 3IOQA 3K24A 2R9MA 3K8UA 1W4TA 1QXPA 2HH5A 2YJBA 4X6HA 3O0UA 4QH6A 3TNXA 1SNKA 4W5BA 2YJ8A 4PP1A 2DZYA 3CH3X 3PDFA 3V6CA 2R9CA 2DCCA 4BSQA 1NB5A 3F5VA 2AIMA 1U9QX 1NL6A 3IV2A 3RVVA 3DF0A 3V6EA 3QJ3A 1ME4A 1GLOA 2G8EA 1QOLA 3M99A 2NQAA 2PADA 3MHHA 2OP3A 3HWNA 1M6DA 2BSZA 3P5XA 4QRXA 4XUIA 3P5WA 2B1NA 2FO5A 2F7DA 4PP2E 4Q8GA 3C9EA 1TLOA 4QRGA 1EWOA 4YYRA 2OULA 4RY2A 3S3RA 4OEMA 4BPVA 1CQDA 1EWLA 2E00A 1POPA 2F1GA 1PXVA 2ACTA 4KLBA 1K3BB 2DCBA 1MEMA 1GMYA 2B1MA 4GUZA 3OF8A 8PCHA 1F2BA 1AIMA 2NQGA 3USVA 1VSNA 4CZWA 1PCIA 4Q8HA 1O0EA 1PPDA 3IEJA 2FTDA 1ZCMA 2AYOA 1THEA 2WBFX 1E2TA 3N3GA 1TU6A 1F29A 5CHVA 1AU2A 2R6NA 3HHIA 2FUDA 2YJCA 3IMAA 1YT7A 2JQGR 3IUTA 3I3TA 4YYUA 1AU3A 4CDFB 1NPZA 4G54A 4QRVA 3KWBX 1W5RA 4OELA 1BGOA 3RVXA 5CVMA 4CDCB 1U9VA 4B55A 2E02A 3NHEA 4YV8A 1YK7A 6PADA 1VJVA 1CTEA 4YYSA 2DC7A 3HHAA 5JA7A 2CB5A 1X9YA 3PW3A 3F75A 3PBHA 1CVZA 5EGWA 1PBHA 4YYVA 1SP4B 2GFOA 4FK5A 2E03A 2AS8A 3ERVA 1KFXL 3KX1A 2XU5A 5CHTA 3BC3A 1MDWA 1ZIVA 4DMYA 4HWYA 1AYUA 4I04A 2JQFR 1PADA 4X6JA 5CVNB 3KKUA 5JH3A 9PAPA 4N8WA 3WXFA 2DJGB 1AYVA 1GX3A 1CV8A 1AU4A 2AUZA 1F2AA 1U9XA 3ZUAA 4BS5A 2FRQA 1PPNA 1GCBA 3B79A 3CBJA 1AU0A 3MORA 2AU1A 4N79A 3KFQA 1U9WA 2DJFB 2BDZA 2VHSA 3H8BA 3CH2X 1MS6A 4NV7A 3WXGA 1BP4A 1KFUL 1NQCA 1YK8A 1MIRA 2NQDB 4YVAA 3D9WA 2R9FA 3QT4A 3S3QA 3K9MA 4W5CA 2G7YA 1PPPA 1W6FA 4P6GA 2P86A 3LFYA 1PIPA 1CS8A 5F02A 2FQ9A 1A6RA 2VFBA 2ARYA 5CVOB 1YALA 3IHPA 1QMYA 1Q6KA 2XU3A 3OVZA 4N4ZA 4YYQA 3CBKA 5A24A 1JQPA 1MEGA 3HD3A 2AUXA 2YJ2A 4MZOA 2C0YA 2P0RA 1U5IA 1QDQA 1CB5A 1IWDA 1AYWA 3U8EA 1CSBB 2G8JA 1HUCB 4K7CA 2VHFA 3RVWA 5K16A 4FJCA 4P6EA 2PBHA 4AXLA 3P5UA 5J94A 1Y4HA 2BDLA 2Y6EA 3BCNA 4QBBA 2P7UA 2HD5A 3WXEA 1BY8A 2O6XA 3N3KA 2DCAA 3H7DA 4X6IA 3BPMA 3BPFA 7PCKA 1CPJA 2FT2A 3AI8A 2GHUA 4NV8A 1GECE 4CDDB 4C5PA 2FYEA 3LXSA 3KW9A 2CIOA 3KSEA 1ATKA 4ZUXU 2XU1A 1KXRA 5PADA 2IBIA 2Y5BA 1MHWA 1NB3A 3OISA 4BQVA 1KHQA 2PREA 3H8CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EF7 A;  1EWM A;  3GCB A;  1DF0 A;  2DC8 A;  2DCD A;  3OF9 A;  1ME3 A;  1ICF A;  1NLJ A;  5EF4 A;  2IPP B;  4YYW A;  2ATO A;  4MSX A;  1AEC A;  1YVB A;  3BOW A;  2DC9 A;  2G6D A;  1PPO A;  2AYN A;  1DEU A;  3BWK A;  2DZZ A;  2R9N A;  3H6S A;  4XR7 A;  4CDE B;  4PI3 A;  3N4C A;  3MHS A;  4AXM A;  2HXZ A;  4MZS A;  1F2C A;  4BS6 A;  2AVW A;  3I06 A;  4I07 A;  1S4V A;  1XKG A;  1PE6 A;  4WA6 A;  2H7J A;  2PNS A;  2R9O A;  1Y08 A;  1ITO A;  2OZ2 A;  3MTN A;  2FRA A;  3E1Z B;  3D6S A;  1FH0 A;  1CJL A;  2DC6 A;  2XU4 A;  3KWZ A;  3OVX A;  3PNR A;  1STF E;  3H89 A;  1TL9 A;  4DMX A;  4W4U A;  1EWP A;  1KHP A;  2NQI A;  3QSD A;  2E01 A;  4I05 A;  4PAD A;  3P5V A;  2YJ9 A;  1BQI A;  2HHN A;  5FPW A;  3O1G A;  4FIP A;  3IOQ A;  3K24 A;  2R9M A;  3K8U A;  1QXP A;  2HH5 A;  2YJB A;  4X6H A;  3O0U A;  4QH6 A;  3TNX A;  1SNK A;  4W5B A;  2YJ8 A;  4PP1 A;  2DZY A;  3CH3 X;  3PDF A;  3V6C A;  2R9C A;  2DCC A;  4BSQ A;  1NB5 A;  3F5V A;  2AIM A;  1U9Q X;  1NL6 A;  3IV2 A;  3RVV A;  3DF0 A;  3V6E A;  3QJ3 A;  1ME4 A;  1GLO A;  2G8E A;  1QOL A;  3M99 A;  2NQA A;  2PAD A;  3MHH A;  2OP3 A;  3HWN A;  1M6D A;  3P5X A;  4QRX A;  4XUI A;  3P5W A;  2B1N A;  2FO5 A;  2F7D A;  4PP2 E;  4Q8G A;  3C9E A;  1TLO A;  4QRG A;  1EWO A;  4YYR A;  2OUL A;  4RY2 A;  3S3R A;  4OEM A;  4BPV A;  1CQD A;  1EWL A;  2E00 A;  1POP A;  2F1G A;  1PXV A;  2ACT A;  4KLB A;  1K3B B;  2DCB A;  1MEM A;  1GMY A;  2B1M A;  3OF8 A;  8PCH A;  1F2B A;  1AIM A;  2NQG A;  3USV A;  1VSN A;  4CZW A;  1PCI A;  4Q8H A;  1O0E A;  1PPD A;  3IEJ A;  2FTD A;  1ZCM A;  2AYO A;  1THE A;  2WBF X;  3N3G A;  1TU6 A;  1F29 A;  5CHV A;  1AU2 A;  2R6N A;  3HHI A;  2FUD A;  2YJC A;  3IMA A;  1YT7 A;  2JQG R;  3IUT A;  3I3T A;  4YYU A;  1AU3 A;  4CDF B;  1NPZ A;  4G54 A;  4QRV A;  3KWB X;  4OEL A;  1BGO A;  3RVX A;  5CVM A;  4CDC B;  1U9V A;  2E02 A;  3NHE A;  4YV8 A;  1YK7 A;  6PAD A;  1VJV A;  1CTE A;  4YYS A;  2DC7 A;  3HHA A;  5JA7 A;  2CB5 A;  1X9Y A;  3PW3 A;  3F75 A;  3PBH A;  1CVZ A;  5EGW A;  1PBH A;  4YYV A;  1SP4 B;  2GFO A;  4FK5 A;  2E03 A;  2AS8 A;  3ERV A;  1KFX L;  3KX1 A;  2XU5 A;  5CHT A;  3BC3 A;  1MDW A;  1ZIV A;  4DMY A;  4HWY A;  1AYU A;  4I04 A;  2JQF R;  1PAD A;  4X6J A;  5CVN B;  3KKU A;  5JH3 A;  9PAP A;  4N8W A;  3WXF A;  2DJG B;  1AYV A;  1CV8 A;  1AU4 A;  2AUZ A;  1F2A A;  1U9X A;  3ZUA A;  4BS5 A;  2FRQ A;  1PPN A;  1GCB A;  3B79 A;  3CBJ A;  1AU0 A;  3MOR A;  2AU1 A;  4N79 A;  3KFQ A;  1U9W A;  2DJF B;  2BDZ A;  2VHS A;  3H8B A;  3CH2 X;  1MS6 A;  3WXG A;  1BP4 A;  1KFU L;  1NQC A;  1YK8 A;  1MIR A;  2NQD B;  4YVA A;  2R9F A;  3QT4 A;  3S3Q A;  3K9M A;  4W5C A;  2G7Y A;  1PPP A;  4P6G A;  2P86 A;  3LFY A;  1PIP A;  1CS8 A;  5F02 A;  2FQ9 A;  1A6R A;  2ARY A;  5CVO B;  1YAL A;  3IHP A;  1QMY A;  1Q6K A;  2XU3 A;  3OVZ A;  4N4Z A;  4YYQ A;  3CBK A;  5A24 A;  1JQP A;  1MEG A;  3HD3 A;  2AUX A;  2YJ2 A;  4MZO A;  2C0Y A;  2P0R A;  1U5I A;  1QDQ A;  1CB5 A;  1IWD A;  1AYW A;  3U8E A;  1CSB B;  2G8J A;  1HUC B;  4K7C A;  2VHF A;  3RVW A;  5K16 A;  4FJC A;  4P6E A;  2PBH A;  4AXL A;  3P5U A;  5J94 A;  1Y4H A;  2BDL A;  2Y6E A;  3BCN A;  4QBB A;  2P7U A;  2HD5 A;  3WXE A;  1BY8 A;  2O6X A;  3N3K A;  2DCA A;  3H7D A;  4X6I A;  3BPM A;  3BPF A;  7PCK A;  1CPJ A;  2FT2 A;  3AI8 A;  2GHU A;  1GEC E;  4CDD B;  2FYE A;  3LXS A;  3KW9 A;  2CIO A;  3KSE A;  1ATK A;  4ZUX U;  2XU1 A;  1KXR A;  5PAD A;  2IBI A;  2Y5B A;  1MHW A;  1NB3 A;  3OIS A;  4BQV A;  1KHQ A;  2PRE A;  3H8C A; 
#chains in the Genus database with same CATH topology
 2HWK A;  1EF7 A;  1EWM A;  3GCB A;  1DF0 A;  4OW0 A;  2DC8 A;  2DCD A;  3PT2 A;  3OF9 A;  4A5U A;  4BOU A;  1ME3 A;  3OQC A;  1ICF A;  1NLJ A;  5EF4 A;  2IPP B;  4YYW A;  2ATO A;  4MSX A;  1AEC A;  1YVB A;  3BOW A;  2DC9 A;  2G6D A;  5E6J A;  1PPO A;  2AYN A;  2FE8 A;  1UKF A;  1DEU A;  3BWK A;  2DZZ A;  2R9N A;  3H6S A;  4XR7 A;  4CDE B;  4PI3 A;  3N4C A;  3MHS A;  4AXM A;  2HXZ A;  4MZS A;  1F2C A;  4BS6 A;  4RKX A;  2AVW A;  3I06 A;  4I07 A;  1S4V A;  1XKG A;  1PE6 A;  4WA6 A;  2H7J A;  2PNS A;  2DOS A;  5EZS A;  2R9O A;  1Y08 A;  1ITO A;  2OZ2 A;  3MTN A;  2FRA A;  5KO3 A;  3E1Z B;  3D6S A;  1FH0 A;  1CJL A;  2DC6 A;  2XU4 A;  3KWZ A;  3TMP A;  3OVX A;  3PNR A;  1STF E;  3H89 A;  1TL9 A;  4DMX A;  4W4U A;  1EWP A;  1KHP A;  2NQI A;  3QSD A;  2E01 A;  4I05 A;  4PAD A;  3P5V A;  2YJ9 A;  1BQI A;  2HHN A;  5FPW A;  3O1G A;  4FIP A;  4D8I A;  3IOQ A;  4D8B A;  3K24 A;  2R9M A;  4RNA A;  3K8U A;  1QXP A;  2HH5 A;  2YJB A;  4X6H A;  3O0U A;  4QH6 A;  3TNX A;  3W30 A;  3RNV A;  1SNK A;  4W5B A;  2YJ8 A;  4PP1 A;  2DZY A;  3CH3 X;  3PDF A;  3V6C A;  2R9C A;  3BB7 A;  4PT5 A;  2DCC A;  4BSQ A;  1NB5 A;  3PRP A;  4BOS A;  3F5V A;  2AIM A;  1U9Q X;  1NL6 A;  3IV2 A;  3RVV A;  3DF0 A;  3V6E A;  3QJ3 A;  1ME4 A;  1GLO A;  2G8E A;  1QOL A;  2Z84 A;  3M99 A;  2NQA A;  2PAD A;  4M0W A;  3MHH A;  2OP3 A;  4GUA A;  3HWN A;  1M6D A;  3P5X A;  3PHW A;  4QRX A;  4XUI A;  2JTC A;  3P5W A;  2B1N A;  2FO5 A;  2F7D A;  4PP2 E;  4Q8G A;  3C9E A;  1TLO A;  4QRG A;  1EWO A;  4YYR A;  2OUL A;  4RY2 A;  3S3R A;  4OEM A;  4BPV A;  1CQD A;  1EWL A;  2E00 A;  1POP A;  2F1G A;  1PXV A;  2ACT A;  4KLB A;  1K3B B;  2DCB A;  2J7Q A;  1MEM A;  1GMY A;  2B1M A;  3OF8 A;  8PCH A;  1F2B A;  1AIM A;  2NQG A;  3PRM A;  3USV A;  1VSN A;  5EZQ A;  4CZW A;  1PCI A;  4Q8H A;  1O0E A;  1PPD A;  3IEJ A;  4BOP A;  2FTD A;  1ZCM A;  2AYO A;  1THE A;  2WBF X;  3N3G A;  1TU6 A;  1F29 A;  5CHV A;  1AU2 A;  2R6N A;  3HHI A;  4REZ A;  2FUD A;  2YJC A;  3IMA A;  1YT7 A;  2JQG R;  3IUT A;  3I3T A;  4YYU A;  1AU3 A;  4CDF B;  1NPZ A;  4G54 A;  4QRV A;  4ZTB A;  3KWB X;  4MM3 B;  4OEL A;  1BGO A;  3RVX A;  5CVM A;  4CDC B;  1U9V A;  2E02 A;  3BBA A;  3NHE A;  4YV8 A;  5JZE A;  1YK7 A;  6PAD A;  1VJV A;  1CTE A;  4YYS A;  2DC7 A;  3HHA A;  5JA7 A;  2CB5 A;  1DKI A;  1X9Y A;  3PW3 A;  3F75 A;  3PBH A;  1CVZ A;  5EGW A;  1PBH A;  4YYV A;  1SP4 B;  2J7Q C;  2GFO A;  4FK5 A;  4OVZ A;  3W31 A;  2E03 A;  2AS8 A;  4HXD B;  3ERV A;  3PHX A;  3MJ5 A;  1KFX L;  3KX1 A;  2JRI A;  2XU5 A;  5CHT A;  3BC3 A;  1MDW A;  1ZIV A;  4DMY A;  4HWY A;  1AYU A;  4RF1 A;  4I04 A;  2JQF R;  1PAD A;  4X6J A;  5CVN B;  3KKU A;  5JH3 A;  9PAP A;  4N8W A;  3E9S A;  4OVZ B;  3WXF A;  2DJG B;  3BY4 A;  3TRK A;  1AYV A;  1CV8 A;  1AU4 A;  1PVJ A;  2AUZ A;  1F2A A;  1U9X A;  3ZNH A;  3ZUA A;  4BS5 A;  2FRQ A;  4IUM A;  1PPN A;  1GCB A;  3B79 A;  3CBJ A;  3PHU A;  1AU0 A;  3MOR A;  2AU1 A;  4N79 A;  3KFQ A;  1U9W A;  2DJF B;  2BDZ A;  2VHS A;  3H8B A;  3CH2 X;  1MS6 A;  3WXG A;  1BP4 A;  1KFU L;  1NQC A;  1YK8 A;  1MIR A;  2NQD B;  4YVA A;  2R9F A;  3QT4 A;  3S3Q A;  4BOZ A;  3K9M A;  3IFU A;  4W5C A;  2G7Y A;  1PPP A;  4P6G A;  2P86 A;  2BTW A;  3LFY A;  1YZB A;  1PIP A;  1CS8 A;  5F02 A;  2FQ9 A;  1A6R A;  2ARY A;  4BOQ A;  5CVO B;  1YAL A;  3IHP A;  4D8E A;  1QMY A;  1Q6K A;  2XU3 A;  2BTW B;  3MP2 A;  3OVZ A;  4N4Z A;  4YYQ A;  3CBK A;  5A24 A;  1JQP A;  3O65 A;  2BU3 A;  1MEG A;  3HD3 A;  2AUX A;  2YJ2 A;  4MZO A;  2C0Y A;  2P0R A;  1U5I A;  1QDQ A;  1CB5 A;  1IWD A;  2AGA A;  1AYW A;  3U8E A;  1CSB B;  2G8J A;  1HUC B;  4MI7 A;  4K7C A;  2VHF A;  3RVW A;  5K16 A;  4IP3 A;  3B21 A;  2UZJ A;  4FJC A;  4P6E A;  2PBH A;  4AXL A;  3P5U A;  5J94 A;  1Y4H A;  3PSE A;  2BDL A;  2Y6E A;  3BCN A;  4QBB A;  2P7U A;  3MTV A;  2HD5 A;  4R3D A;  4XZX A;  3WXE A;  4P16 A;  1BY8 A;  2O6X A;  3N3K A;  2DCA A;  3H7D A;  4X6I A;  3BPM A;  3BPF A;  7PCK A;  3C0R A;  1CPJ A;  2FT2 A;  3AI8 A;  2GHU A;  1GEC E;  4CDD B;  2FYE A;  3LXS A;  3KW9 A;  2CIO A;  3KSE A;  1ATK A;  4ZUX U;  2XU1 A;  1KXR A;  5PAD A;  2IBI A;  2Y5B A;  1MHW A;  4RF0 A;  1NB3 A;  3OIS A;  4BQV A;  1KHQ A;  2PRE A;  4WUR A;  3H8C A; 
#chains in the Genus database with same CATH homology
 1EF7 A;  1EWM A;  3GCB A;  1DF0 A;  2DC8 A;  2DCD A;  3OF9 A;  1ME3 A;  1ICF A;  1NLJ A;  4BGF A;  5EF4 A;  2IPP B;  4YYW A;  2ATO A;  4MSX A;  1AEC A;  3LTW A;  1YVB A;  3BOW A;  2DC9 A;  2G6D A;  1PPO A;  2AYN A;  1DEU A;  3BWK A;  2DZZ A;  2R9N A;  3H6S A;  4XR7 A;  4CDE B;  4PI3 A;  3N4C A;  3MHS A;  4AXM A;  2HXZ A;  4MZS A;  1F2C A;  4BS6 A;  2AVW A;  3I06 A;  4I07 A;  1S4V A;  1XKG A;  1PE6 A;  4WA6 A;  2H7J A;  2PNS A;  2R9O A;  1Y08 A;  1ITO A;  2OZ2 A;  2VFC A;  3MTN A;  2FRA A;  3E1Z B;  3D6S A;  1FH0 A;  1CJL A;  2DC6 A;  2XU4 A;  3KWZ A;  3OVX A;  3PNR A;  1STF E;  3H89 A;  1TL9 A;  4DMX A;  4W4U A;  1EWP A;  1KHP A;  2NQI A;  3QSD A;  2E01 A;  4I05 A;  4PAD A;  3P5V A;  2YJ9 A;  1BQI A;  2HHN A;  5FPW A;  3O1G A;  4FIP A;  3IOQ A;  3K24 A;  2R9M A;  3K8U A;  1W4T A;  1QXP A;  2HH5 A;  2YJB A;  4X6H A;  3O0U A;  4QH6 A;  3TNX A;  1SNK A;  4W5B A;  2YJ8 A;  4PP1 A;  2DZY A;  3CH3 X;  3PDF A;  3V6C A;  2R9C A;  2DCC A;  4BSQ A;  1NB5 A;  3F5V A;  2AIM A;  1U9Q X;  1NL6 A;  3IV2 A;  3RVV A;  3DF0 A;  3V6E A;  3QJ3 A;  1ME4 A;  1GLO A;  2G8E A;  1QOL A;  3M99 A;  2NQA A;  2PAD A;  3MHH A;  2OP3 A;  3HWN A;  1M6D A;  2BSZ A;  3P5X A;  4QRX A;  4XUI A;  3P5W A;  2B1N A;  2FO5 A;  2F7D A;  4PP2 E;  4Q8G A;  3C9E A;  1TLO A;  4QRG A;  1EWO A;  4YYR A;  2OUL A;  4RY2 A;  3S3R A;  4OEM A;  4BPV A;  1CQD A;  1EWL A;  2E00 A;  1POP A;  2F1G A;  1PXV A;  2ACT A;  4KLB A;  1K3B B;  2DCB A;  1MEM A;  1GMY A;  2B1M A;  4GUZ A;  3OF8 A;  8PCH A;  1F2B A;  1AIM A;  2NQG A;  3USV A;  1VSN A;  4CZW A;  1PCI A;  4Q8H A;  1O0E A;  1PPD A;  3IEJ A;  2FTD A;  1ZCM A;  2AYO A;  1THE A;  2WBF X;  1E2T A;  3N3G A;  1TU6 A;  1F29 A;  5CHV A;  1AU2 A;  2R6N A;  3HHI A;  2FUD A;  2YJC A;  3IMA A;  1YT7 A;  2JQG R;  3IUT A;  3I3T A;  4YYU A;  1AU3 A;  4CDF B;  1NPZ A;  4G54 A;  4QRV A;  3KWB X;  1W5R A;  4OEL A;  1BGO A;  3RVX A;  5CVM A;  4CDC B;  1U9V A;  4B55 A;  2E02 A;  3NHE A;  4YV8 A;  1YK7 A;  6PAD A;  1VJV A;  1CTE A;  4YYS A;  2DC7 A;  3HHA A;  5JA7 A;  2CB5 A;  1X9Y A;  3PW3 A;  3F75 A;  3PBH A;  1CVZ A;  5EGW A;  1PBH A;  4YYV A;  1SP4 B;  2GFO A;  4FK5 A;  2E03 A;  2AS8 A;  3ERV A;  1KFX L;  3KX1 A;  2XU5 A;  5CHT A;  3BC3 A;  1MDW A;  1ZIV A;  4DMY A;  4HWY A;  1AYU A;  4I04 A;  2JQF R;  1PAD A;  4X6J A;  5CVN B;  3KKU A;  5JH3 A;  9PAP A;  4N8W A;  3WXF A;  2DJG B;  1AYV A;  1GX3 A;  1CV8 A;  1AU4 A;  2AUZ A;  1F2A A;  1U9X A;  3ZUA A;  4BS5 A;  2FRQ A;  1PPN A;  1GCB A;  3B79 A;  3CBJ A;  1AU0 A;  3MOR A;  2AU1 A;  4N79 A;  3KFQ A;  1U9W A;  2DJF B;  2BDZ A;  2VHS A;  3H8B A;  3CH2 X;  1MS6 A;  4NV7 A;  3WXG A;  1BP4 A;  1KFU L;  1NQC A;  1YK8 A;  1MIR A;  2NQD B;  4YVA A;  3D9W A;  2R9F A;  3QT4 A;  3S3Q A;  3K9M A;  4W5C A;  2G7Y A;  1PPP A;  1W6F A;  4P6G A;  2P86 A;  3LFY A;  1PIP A;  1CS8 A;  5F02 A;  2FQ9 A;  1A6R A;  2VFB A;  2ARY A;  5CVO B;  1YAL A;  3IHP A;  1QMY A;  1Q6K A;  2XU3 A;  3OVZ A;  4N4Z A;  4YYQ A;  3CBK A;  5A24 A;  1JQP A;  1MEG A;  3HD3 A;  2AUX A;  2YJ2 A;  4MZO A;  2C0Y A;  2P0R A;  1U5I A;  1QDQ A;  1CB5 A;  1IWD A;  1AYW A;  3U8E A;  1CSB B;  2G8J A;  1HUC B;  4K7C A;  2VHF A;  3RVW A;  5K16 A;  4FJC A;  4P6E A;  2PBH A;  4AXL A;  3P5U A;  5J94 A;  1Y4H A;  2BDL A;  2Y6E A;  3BCN A;  4QBB A;  2P7U A;  2HD5 A;  3WXE A;  1BY8 A;  2O6X A;  3N3K A;  2DCA A;  3H7D A;  4X6I A;  3BPM A;  3BPF A;  7PCK A;  1CPJ A;  2FT2 A;  3AI8 A;  2GHU A;  4NV8 A;  1GEC E;  4CDD B;  4C5P A;  2FYE A;  3LXS A;  3KW9 A;  2CIO A;  3KSE A;  1ATK A;  4ZUX U;  2XU1 A;  1KXR A;  5PAD A;  2IBI A;  2Y5B A;  1MHW A;  1NB3 A;  3OIS A;  4BQV A;  1KHQ A;  2PRE A;  3H8C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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