3H89A

A combined crystallographic and molecular dynamics study of cathepsin-l retro-binding inhibitors(compound 4)
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
220
structure length
215
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A combined crystallographic and molecular dynamics study of cathepsin L retrobinding inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin L1
total genus 69
structure length 215
sequence length 220
chains with identical sequence B, C, D, E, F
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2009-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3h89A00
4AXMA 1VSNA 4X6HA 2F7DA 2NQGA 4W5CA 1YK8A 4PP1A 4CDEB 1CTEA 3USVA 2G8JA 2YJ9A 1GLOA 1POPA 2JQFR 3H8CA 4X6IA 3P5UA 4I07A 2R6NA 1PADA 3LXSA 1U9XA 1MS6A 4FK5A 4P6GA 1EWPA 2PBHA 1AU0A 3E1ZB 4DMYA 1CV8A 1MEMA 3CBKA 1THEA 3IV2A 2DC9A 2FRQA 4BSQA 2CIOA 2XU4A 4WA6A 1O0EA 3TNXA 1KXRA 4YVAA 3P5VA 2AUZA 2AU1A 4QBBA 4X6JA 3RVVA 3KSEA 1MDWA 3HWNA 9PAPA 4CDDB 1VJVA 2R9FA 1ICFA 3BPFA 3H8BA 3MTNA 3N3KA 1CVZA 5FPWA 3OF9A 4G54A 4RY2A 2NQDB 3M99A 3MHSA 2C0YA 5PADA 2FUDA 2PNSA 3I3TA 2HXZA 1QMYA 1AYUA 1PPNA 4YV8A 2VHFA 2DC6A 1AU2A 5J94A 5K16A 1AYWA 1JQPA 3IMAA 3F5VA 3V6EA 4W5BA 2G6DA 1AU3A 1U9QX 1SNKA 1YT7A 2IBIA 3BPMA 3O1GA 4N8WA 2FQ9A 4QRVA 2PADA 4QRGA 3OISA 3QJ3A 1GECE 4YYQA 1BY8A 1AU4A 2P7UA 2FTDA 3KX1A 4PP2E 2P0RA 3K9MA 3GCBA 4OELA 4BQVA 1GMYA 2AUXA 1IWDA 3IOQA 1BP4A 1YALA 3HHIA 1KFXL 1ZIVA 1NQCA 2B1MA 2CB5A 2OZ2A 1EWOA 4YYSA 3N4CA 2YJ8A 1ATKA 1A6RA 1U9WA 5CVMA 1PE6A 2OULA 3MHHA 1AYVA 2AIMA 2Y6EA 1PXVA 3MORA 1QDQA 2FRAA 1F2CA 2R9CA 3IEJA 1YVBA 4N4ZA 3N3GA 3CH3X 1CJLA 6PADA 1TL9A 2DZYA 4YYRA 2BDLA 4MSXA 2DC7A 4N79A 1X9YA 4Q8HA 1F29A 3RVWA 3O0UA 4YYUA 5CVOB 3OVZA 3IHPA 1KFUL 4P6EA 3V6CA 1EWLA 3OF8A 3I06A 1NPZA 2AVWA 3IUTA 4PI3A 4CZWA 3H6SA 5A24A 1NB5A 1XKGA 4MZOA 2GFOA 3D6SA 2YJ2A 1K3BB 1ME4A 3WXGA 3HD3A 1KHPA 4YYVA 4BPVA 2GHUA 2Y5BA 4BS6A 3NHEA 3K24A 1PBHA 4BS5A 3KWBX 4CDCB 3F75A 2AS8A 3KW9A 2DJGB 2F1GA 3AI8A 5CHTA 1STFE 1AIMA 2E02A 4KLBA 1MHWA 4HWYA 1M6DA 3BWKA 3KWZA 2DCCA 5EF4A 2R9MA 3KFQA 2B1NA 3U8EA 2XU3A 2DCAA 4OEMA 1Q6KA 2WBFX 1ME3A 2FYEA 3P5XA 2DCDA 2H7JA 2G7YA 2JQGR 1QXPA 2PREA 4YYWA 1U9VA 3CBJA 5JH3A 1BGOA 1CSBB 3HHAA 2YJCA 1MEGA 4QH6A 1PCIA 4I04A 3BC3A 1NB3A 2DC8A 1HUCB 1CPJA 1CS8A 5JA7A 3KKUA 1PPPA 1PPDA 3S3RA 3ZUAA 4FIPA 5F02A 7PCKA 1TLOA 4K7CA 3H7DA 2E00A 1SP4B 2P86A 3H89A 2ACTA 3PBHA 2NQIA 2HH5A 2BDZA 1CQDA 1ZCMA 1PIPA 2HHNA 1TU6A 3QT4A 4I05A 1EWMA 2R9OA 2O6XA 4XR7A 3OVXA 2DJFB 1YK7A 2OP3A 2DCBA 1FH0A 5CHVA 1S4VA 1MIRA 3C9EA 1U5IA 2R9NA 2NQAA 4CDFB 1Y4HA 3ERVA 1DEUA 1GCBA 1F2BA 1NLJA 2DZZA 4ZUXU 1PPOA 3QSDA 2XU5A 2AYOA 3WXEA 1KHQA 5EGWA 1DF0A 4FJCA 3BOWA 4AXLA 3BCNA 4DMXA 2E03A 3WXFA 4W4UA 2E01A 5CVNB 4XUIA 4Q8GA 4MZSA 1BQIA 2FO5A 3PDFA 8PCHA 3CH2X 4QRXA 2YJBA 1CB5A 3PW3A 3DF0A 2VHSA 2ATOA 1F2AA 3LFYA 3P5WA 3RVXA 3S3QA 2FT2A 1EF7A 3PNRA 2G8EA 3B79A 2HD5A 2IPPB 2XU1A 1QOLA 3K8UA 1ITOA 4PADA 1NL6A 2AYNA 2ARYA 1AECA 1Y08A
chains in the Genus database with same CATH superfamily
4AXMA 1VSNA 4X6HA 2F7DA 2NQGA 4W5CA 3RNVA 1YK8A 4PP1A 4CDEB 1CTEA 3USVA 2G8JA 2YJ9A 1GLOA 1POPA 2BU3A 2JQFR 3H8CA 4IUMA 4X6IA 3P5UA 4I07A 2R6NA 1PADA 3LXSA 1YZBA 1U9XA 1MS6A 4FK5A 5EZQA 4P6GA 1EWPA 2PBHA 1AU0A 3E1ZB 4DMYA 1CV8A 1MEMA 3CBKA 1THEA 1PVJA 2BTWB 3BBAA 3IV2A 2DC9A 2FRQA 4BSQA 2CIOA 2XU4A 4WA6A 1O0EA 3TNXA 1KXRA 4YVAA 3P5VA 2FE8A 2AUZA 2AU1A 4QBBA 4X6JA 3RVVA 3KSEA 1MDWA 4R3DA 3HWNA 3PRPA 9PAPA 4CDDB 1VJVA 2R9FA 4REZA 1ICFA 3BPFA 3H8BA 3ZNHA 3MTNA 4GUAA 3N3KA 1CVZA 5FPWA 3OF9A 4G54A 4RY2A 2NQDB 3M99A 3MHSA 2C0YA 5PADA 2FUDA 2PNSA 3I3TA 2HXZA 1QMYA 1AYUA 1PPNA 2JTCA 4YV8A 4MM3B 3MTVA 5JZEA 2VHFA 2DC6A 4BOZA 1AU2A 5J94A 5K16A 1AYWA 1JQPA 3IMAA 4BOPA 3F5VA 3V6EA 4W5BA 2G6DA 1AU3A 1U9QX 1SNKA 1YT7A 2IBIA 4RNAA 3BPMA 3OQCA 3O1GA 4N8WA 2FQ9A 4QRVA 4A5UA 2PADA 4QRGA 4ZTBA 3OISA 3QJ3A 1GECE 4YYQA 1BY8A 1AU4A 2P7UA 2FTDA 3KX1A 4PP2E 2P0RA 3K9MA 3GCBA 3W30A 4OELA 4BQVA 1GMYA 2AUXA 1IWDA 3IOQA 1BP4A 1YALA 3C0RA 3HHIA 1KFXL 1ZIVA 1NQCA 2B1MA 2CB5A 2OZ2A 2DOSA 1EWOA 4YYSA 3N4CA 2YJ8A 1ATKA 1A6RA 1U9WA 5CVMA 1PE6A 2OULA 3MHHA 1AYVA 2AIMA 3TRKA 2Y6EA 1PXVA 3MORA 1QDQA 2FRAA 1F2CA 2R9CA 3IEJA 1YVBA 4N4ZA 3N3GA 2JRIA 3CH3X 5KO3A 1CJLA 6PADA 1TL9A 2DZYA 4YYRA 2BDLA 4MSXA 2DC7A 4N79A 4OVZA 1X9YA 4Q8HA 1F29A 3RVWA 3O0UA 4YYUA 5CVOB 3OVZA 3IHPA 1KFUL 4P6EA 3V6CA 1EWLA 3OF8A 3I06A 1NPZA 2UZJA 3IUTA 2AVWA 4PI3A 3IFUA 4CZWA 3H6SA 5A24A 1NB5A 1XKGA 4MZOA 2GFOA 3D6SA 2YJ2A 1K3BB 1ME4A 3WXGA 3HD3A 2J7QA 1KHPA 4YYVA 4BPVA 2GHUA 2Y5BA 4BS6A 4RKXA 3NHEA 3K24A 2J7QC 1PBHA 4BS5A 3KWBX 4PT5A 4CDCB 3PHWA 3F75A 2AS8A 3TMPA 3KW9A 2DJGB 2F1GA 3AI8A 5CHTA 4M0WA 1STFE 1AIMA 2E02A 3PRMA 4KLBA 1MHWA 4HWYA 1M6DA 3BWKA 3KWZA 2DCCA 5EF4A 2R9MA 3KFQA 2B1NA 3U8EA 2XU3A 4P16A 3MP2A 2DCAA 4WURA 4OEMA 1Q6KA 2WBFX 1ME3A 2FYEA 3P5XA 4D8IA 5EZSA 2DCDA 2H7JA 5E6JA 2G7YA 2JQGR 1QXPA 2PREA 4YYWA 1U9VA 3CBJA 5JH3A 1BGOA 1CSBB 3B21A 3HHAA 2YJCA 1MEGA 4QH6A 1PCIA 4I04A 3BC3A 1NB3A 4MI7A 2DC8A 1HUCB 1CPJA 1CS8A 2HWKA 5JA7A 3KKUA 1PPPA 1PPDA 3S3RA 3ZUAA 4FIPA 5F02A 7PCKA 1TLOA 3H7DA 4K7CA 2E00A 1SP4B 2P86A 3H89A 2ACTA 3PBHA 2NQIA 2HH5A 3PT2A 2BDZA 2BTWA 1CQDA 1ZCMA 3W31A 1PIPA 2HHNA 1TU6A 3QT4A 4I05A 1EWMA 2R9OA 2O6XA 4RF1A 4XR7A 2Z84A 3OVXA 4D8EA 2DJFB 4OVZB 1YK7A 2OP3A 2DCBA 1FH0A 5CHVA 1S4VA 1MIRA 3C9EA 1U5IA 2R9NA 2NQAA 4CDFB 1Y4HA 3BY4A 3ERVA 1DEUA 3PHUA 1GCBA 4XZXA 1F2BA 1NLJA 2DZZA 4ZUXU 4BOUA 4BOSA 1PPOA 3QSDA 4RF0A 2XU5A 2AYOA 3WXEA 1KHQA 5EGWA 1DF0A 4FJCA 2AGAA 3BOWA 4OW0A 4AXLA 3BCNA 4DMXA 3BB7A 2E03A 3WXFA 4W4UA 2E01A 4D8BA 5CVNB 4XUIA 4Q8GA 3O65A 4MZSA 1BQIA 2FO5A 3PDFA 8PCHA 3CH2X 1UKFA 4QRXA 2YJBA 1CB5A 3PW3A 3DF0A 2VHSA 2ATOA 3MJ5A 4IP3A 1F2AA 3LFYA 3P5WA 3RVXA 3S3QA 2FT2A 4BOQA 1EF7A 3PNRA 1DKIA 2G8EA 3B79A 3E9SA 2HD5A 2IPPB 2XU1A 3PHXA 1QOLA 3K8UA 1ITOA 4PADA 1NL6A 2AYNA 3PSEA 4HXDB 2ARYA 1AECA 1Y08A
chains in the Genus database with same CATH topology
4AXMA 1VSNA 4X6HA 2F7DA 2NQGA 4W5CA 1YK8A 4PP1A 4CDEB 1CTEA 3USVA 2G8JA 2YJ9A 1GLOA 1POPA 2JQFR 3H8CA 4X6IA 3P5UA 4I07A 2R6NA 1PADA 3LXSA 1U9XA 1MS6A 4FK5A 4P6GA 1EWPA 2PBHA 1AU0A 3E1ZB 4DMYA 1CV8A 1MEMA 3CBKA 1THEA 3IV2A 2DC9A 2FRQA 4BSQA 4C5PA 2CIOA 2XU4A 4WA6A 1O0EA 3TNXA 1KXRA 4YVAA 3P5VA 2AUZA 2AU1A 4QBBA 2VFBA 4X6JA 3RVVA 3KSEA 1MDWA 3HWNA 9PAPA 4CDDB 1VJVA 2R9FA 1ICFA 3BPFA 3H8BA 3MTNA 3N3KA 1CVZA 5FPWA 3OF9A 4G54A 4RY2A 2NQDB 3M99A 3MHSA 2C0YA 1W6FA 2FUDA 5PADA 2PNSA 3I3TA 2HXZA 1QMYA 1AYUA 1PPNA 4YV8A 2VHFA 2DC6A 1AU2A 5J94A 5K16A 1AYWA 3D9WA 1JQPA 3IMAA 3F5VA 3V6EA 4W5BA 2G6DA 1AU3A 1U9QX 1SNKA 1YT7A 2IBIA 3BPMA 3O1GA 4N8WA 2FQ9A 4QRVA 2PADA 4QRGA 3OISA 3QJ3A 1GECE 4YYQA 1BY8A 1AU4A 2P7UA 2FTDA 3KX1A 4PP2E 2P0RA 3K9MA 3GCBA 4OELA 4BQVA 1GMYA 2AUXA 1IWDA 3IOQA 1BP4A 1YALA 3HHIA 1KFXL 1ZIVA 1NQCA 2B1MA 2CB5A 2OZ2A 1EWOA 4YYSA 3N4CA 2YJ8A 1ATKA 1A6RA 1U9WA 5CVMA 1PE6A 2OULA 3MHHA 1AYVA 2AIMA 2Y6EA 1PXVA 3MORA 1QDQA 2FRAA 1F2CA 2R9CA 3LTWA 3IEJA 1YVBA 4N4ZA 3N3GA 3CH3X 1CJLA 6PADA 1TL9A 2DZYA 4YYRA 2BDLA 4MSXA 2DC7A 4N79A 1X9YA 4Q8HA 1F29A 3RVWA 3O0UA 4YYUA 4B55A 5CVOB 3OVZA 3IHPA 4NV7A 1KFUL 4P6EA 3V6CA 1EWLA 3OF8A 3I06A 1NPZA 3IUTA 2AVWA 4PI3A 4CZWA 3H6SA 5A24A 1NB5A 1XKGA 4MZOA 2GFOA 3D6SA 2YJ2A 1K3BB 1ME4A 3WXGA 3HD3A 1KHPA 4YYVA 4BPVA 2GHUA 2Y5BA 4BS6A 1GX3A 3NHEA 3K24A 1PBHA 4BS5A 3KWBX 4CDCB 3F75A 2AS8A 3KW9A 2DJGB 2F1GA 3AI8A 5CHTA 1STFE 1AIMA 2E02A 4KLBA 1MHWA 4HWYA 1M6DA 3BWKA 3KWZA 2DCCA 5EF4A 2R9MA 3KFQA 2B1NA 3U8EA 2XU3A 2DCAA 4OEMA 1Q6KA 2WBFX 1ME3A 2FYEA 3P5XA 2DCDA 2H7JA 2G7YA 2JQGR 1QXPA 2PREA 4YYWA 1U9VA 3CBJA 5JH3A 1BGOA 1CSBB 3HHAA 2YJCA 1MEGA 4QH6A 1PCIA 4I04A 3BC3A 1NB3A 2DC8A 1HUCB 1CPJA 1CS8A 5JA7A 3KKUA 1PPPA 1PPDA 3S3RA 3ZUAA 4FIPA 5F02A 2VFCA 7PCKA 1TLOA 4K7CA 3H7DA 2E00A 1SP4B 2P86A 3H89A 2ACTA 3PBHA 2NQIA 2HH5A 2BDZA 1CQDA 1ZCMA 1PIPA 2HHNA 1TU6A 3QT4A 4I05A 1EWMA 2R9OA 2O6XA 4XR7A 3OVXA 2DJFB 1YK7A 2OP3A 2DCBA 1FH0A 5CHVA 1S4VA 1MIRA 3C9EA 1U5IA 2R9NA 2NQAA 4CDFB 1Y4HA 2BSZA 3ERVA 1DEUA 1GCBA 1F2BA 1NLJA 2DZZA 4ZUXU 1PPOA 3QSDA 2XU5A 2AYOA 3WXEA 1KHQA 5EGWA 1DF0A 4FJCA 3BOWA 4AXLA 3BCNA 4GUZA 4DMXA 2E03A 3WXFA 1E2TA 4W4UA 2E01A 5CVNB 4XUIA 4Q8GA 4MZSA 1BQIA 2FO5A 3PDFA 8PCHA 3CH2X 4QRXA 2YJBA 1CB5A 3PW3A 4BGFA 3DF0A 2VHSA 2ATOA 1F2AA 3LFYA 3P5WA 3RVXA 3S3QA 2FT2A 1EF7A 3PNRA 1W5RA 2G8EA 3B79A 2HD5A 2IPPB 2XU1A 1QOLA 3K8UA 1W4TA 1ITOA 4PADA 1NL6A 4NV8A 2AYNA 2ARYA 1AECA 1Y08A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AXM A;  1VSN A;  4X6H A;  2F7D A;  2NQG A;  4W5C A;  1YK8 A;  4PP1 A;  4CDE B;  1CTE A;  3USV A;  2G8J A;  2YJ9 A;  1GLO A;  1POP A;  2JQF R;  3H8C A;  4X6I A;  3P5U A;  4I07 A;  2R6N A;  1PAD A;  3LXS A;  1U9X A;  1MS6 A;  4FK5 A;  4P6G A;  1EWP A;  2PBH A;  1AU0 A;  3E1Z B;  4DMY A;  1CV8 A;  1MEM A;  3CBK A;  1THE A;  3IV2 A;  2DC9 A;  2FRQ A;  4BSQ A;  2CIO A;  2XU4 A;  4WA6 A;  1O0E A;  3TNX A;  1KXR A;  4YVA A;  3P5V A;  2AUZ A;  2AU1 A;  4QBB A;  4X6J A;  3RVV A;  3KSE A;  1MDW A;  3HWN A;  9PAP A;  4CDD B;  1VJV A;  2R9F A;  1ICF A;  3BPF A;  3H8B A;  3MTN A;  3N3K A;  1CVZ A;  5FPW A;  3OF9 A;  4G54 A;  4RY2 A;  2NQD B;  3M99 A;  3MHS A;  2C0Y A;  5PAD A;  2FUD A;  2PNS A;  3I3T A;  2HXZ A;  1QMY A;  1AYU A;  1PPN A;  4YV8 A;  2VHF A;  2DC6 A;  1AU2 A;  5J94 A;  5K16 A;  1AYW A;  1JQP A;  3IMA A;  3F5V A;  3V6E A;  4W5B A;  2G6D A;  1AU3 A;  1U9Q X;  1SNK A;  1YT7 A;  2IBI A;  3BPM A;  3O1G A;  4N8W A;  2FQ9 A;  4QRV A;  2PAD A;  4QRG A;  3OIS A;  3QJ3 A;  1GEC E;  4YYQ A;  1BY8 A;  1AU4 A;  2P7U A;  2FTD A;  3KX1 A;  4PP2 E;  2P0R A;  3K9M A;  3GCB A;  4OEL A;  4BQV A;  1GMY A;  2AUX A;  1IWD A;  3IOQ A;  1BP4 A;  1YAL A;  3HHI A;  1KFX L;  1ZIV A;  1NQC A;  2B1M A;  2CB5 A;  2OZ2 A;  1EWO A;  4YYS A;  3N4C A;  2YJ8 A;  1ATK A;  1A6R A;  1U9W A;  5CVM A;  1PE6 A;  2OUL A;  3MHH A;  1AYV A;  2AIM A;  2Y6E A;  1PXV A;  3MOR A;  1QDQ A;  2FRA A;  1F2C A;  2R9C A;  3IEJ A;  1YVB A;  4N4Z A;  3N3G A;  3CH3 X;  1CJL A;  6PAD A;  1TL9 A;  2DZY A;  4YYR A;  2BDL A;  4MSX A;  2DC7 A;  4N79 A;  1X9Y A;  4Q8H A;  1F29 A;  3RVW A;  3O0U A;  4YYU A;  5CVO B;  3OVZ A;  3IHP A;  1KFU L;  4P6E A;  3V6C A;  1EWL A;  3OF8 A;  3I06 A;  1NPZ A;  2AVW A;  3IUT A;  4PI3 A;  4CZW A;  3H6S A;  5A24 A;  1NB5 A;  1XKG A;  4MZO A;  2GFO A;  3D6S A;  2YJ2 A;  1K3B B;  1ME4 A;  3WXG A;  3HD3 A;  1KHP A;  4YYV A;  4BPV A;  2GHU A;  2Y5B A;  4BS6 A;  3NHE A;  3K24 A;  1PBH A;  4BS5 A;  3KWB X;  4CDC B;  3F75 A;  2AS8 A;  3KW9 A;  2DJG B;  2F1G A;  3AI8 A;  5CHT A;  1STF E;  1AIM A;  2E02 A;  4KLB A;  1MHW A;  4HWY A;  1M6D A;  3BWK A;  3KWZ A;  2DCC A;  5EF4 A;  2R9M A;  3KFQ A;  2B1N A;  3U8E A;  2XU3 A;  2DCA A;  4OEM A;  1Q6K A;  2WBF X;  1ME3 A;  2FYE A;  3P5X A;  2DCD A;  2H7J A;  2G7Y A;  2JQG R;  1QXP A;  2PRE A;  4YYW A;  1U9V A;  3CBJ A;  5JH3 A;  1BGO A;  1CSB B;  3HHA A;  2YJC A;  1MEG A;  4QH6 A;  1PCI A;  4I04 A;  3BC3 A;  1NB3 A;  2DC8 A;  1HUC B;  1CPJ A;  1CS8 A;  5JA7 A;  3KKU A;  1PPP A;  1PPD A;  3S3R A;  3ZUA A;  4FIP A;  5F02 A;  7PCK A;  1TLO A;  4K7C A;  3H7D A;  2E00 A;  1SP4 B;  2P86 A;  3H89 A;  2ACT A;  3PBH A;  2NQI A;  2HH5 A;  2BDZ A;  1CQD A;  1ZCM A;  1PIP A;  2HHN A;  1TU6 A;  3QT4 A;  4I05 A;  1EWM A;  2R9O A;  2O6X A;  4XR7 A;  3OVX A;  2DJF B;  1YK7 A;  2OP3 A;  2DCB A;  1FH0 A;  5CHV A;  1S4V A;  1MIR A;  3C9E A;  1U5I A;  2R9N A;  2NQA A;  4CDF B;  1Y4H A;  3ERV A;  1DEU A;  1GCB A;  1F2B A;  1NLJ A;  2DZZ A;  4ZUX U;  1PPO A;  3QSD A;  2XU5 A;  2AYO A;  3WXE A;  1KHQ A;  5EGW A;  1DF0 A;  4FJC A;  3BOW A;  4AXL A;  3BCN A;  4DMX A;  2E03 A;  3WXF A;  4W4U A;  2E01 A;  5CVN B;  4XUI A;  4Q8G A;  4MZS A;  1BQI A;  2FO5 A;  3PDF A;  8PCH A;  3CH2 X;  4QRX A;  2YJB A;  1CB5 A;  3PW3 A;  3DF0 A;  2VHS A;  2ATO A;  1F2A A;  3LFY A;  3P5W A;  3RVX A;  3S3Q A;  2FT2 A;  1EF7 A;  3PNR A;  2G8E A;  3B79 A;  2HD5 A;  2IPP B;  2XU1 A;  1QOL A;  3K8U A;  1ITO A;  4PAD A;  1NL6 A;  2AYN A;  2ARY A;  1AEC A;  1Y08 A; 
#chains in the Genus database with same CATH topology
 4AXM A;  1VSN A;  4X6H A;  2F7D A;  2NQG A;  4W5C A;  3RNV A;  1YK8 A;  4PP1 A;  4CDE B;  1CTE A;  3USV A;  2G8J A;  2YJ9 A;  1GLO A;  1POP A;  2BU3 A;  2JQF R;  3H8C A;  4IUM A;  4X6I A;  3P5U A;  4I07 A;  2R6N A;  1PAD A;  3LXS A;  1YZB A;  1U9X A;  1MS6 A;  4FK5 A;  5EZQ A;  4P6G A;  1EWP A;  2PBH A;  1AU0 A;  3E1Z B;  4DMY A;  1CV8 A;  1MEM A;  3CBK A;  1THE A;  1PVJ A;  2BTW B;  3BBA A;  3IV2 A;  2DC9 A;  2FRQ A;  4BSQ A;  2CIO A;  2XU4 A;  4WA6 A;  1O0E A;  3TNX A;  1KXR A;  4YVA A;  3P5V A;  2FE8 A;  2AUZ A;  2AU1 A;  4QBB A;  4X6J A;  3RVV A;  3KSE A;  1MDW A;  4R3D A;  3HWN A;  3PRP A;  9PAP A;  4CDD B;  1VJV A;  2R9F A;  4REZ A;  1ICF A;  3BPF A;  3H8B A;  3ZNH A;  3MTN A;  4GUA A;  3N3K A;  1CVZ A;  5FPW A;  3OF9 A;  4G54 A;  4RY2 A;  2NQD B;  3M99 A;  3MHS A;  2C0Y A;  5PAD A;  2FUD A;  2PNS A;  3I3T A;  2HXZ A;  1QMY A;  1AYU A;  1PPN A;  2JTC A;  4YV8 A;  4MM3 B;  3MTV A;  5JZE A;  2VHF A;  2DC6 A;  4BOZ A;  1AU2 A;  5J94 A;  5K16 A;  1AYW A;  1JQP A;  3IMA A;  4BOP A;  3F5V A;  3V6E A;  4W5B A;  2G6D A;  1AU3 A;  1U9Q X;  1SNK A;  1YT7 A;  2IBI A;  4RNA A;  3BPM A;  3OQC A;  3O1G A;  4N8W A;  2FQ9 A;  4QRV A;  4A5U A;  2PAD A;  4QRG A;  4ZTB A;  3OIS A;  3QJ3 A;  1GEC E;  4YYQ A;  1BY8 A;  1AU4 A;  2P7U A;  2FTD A;  3KX1 A;  4PP2 E;  2P0R A;  3K9M A;  3GCB A;  3W30 A;  4OEL A;  4BQV A;  1GMY A;  2AUX A;  1IWD A;  3IOQ A;  1BP4 A;  1YAL A;  3C0R A;  3HHI A;  1KFX L;  1ZIV A;  1NQC A;  2B1M A;  2CB5 A;  2OZ2 A;  2DOS A;  1EWO A;  4YYS A;  3N4C A;  2YJ8 A;  1ATK A;  1A6R A;  1U9W A;  5CVM A;  1PE6 A;  2OUL A;  3MHH A;  1AYV A;  2AIM A;  3TRK A;  2Y6E A;  1PXV A;  3MOR A;  1QDQ A;  2FRA A;  1F2C A;  2R9C A;  3IEJ A;  1YVB A;  4N4Z A;  3N3G A;  2JRI A;  3CH3 X;  5KO3 A;  1CJL A;  6PAD A;  1TL9 A;  2DZY A;  4YYR A;  2BDL A;  4MSX A;  2DC7 A;  4N79 A;  4OVZ A;  1X9Y A;  4Q8H A;  1F29 A;  3RVW A;  3O0U A;  4YYU A;  5CVO B;  3OVZ A;  3IHP A;  1KFU L;  4P6E A;  3V6C A;  1EWL A;  3OF8 A;  3I06 A;  1NPZ A;  2UZJ A;  3IUT A;  2AVW A;  4PI3 A;  3IFU A;  4CZW A;  3H6S A;  5A24 A;  1NB5 A;  1XKG A;  4MZO A;  2GFO A;  3D6S A;  2YJ2 A;  1K3B B;  1ME4 A;  3WXG A;  3HD3 A;  2J7Q A;  1KHP A;  4YYV A;  4BPV A;  2GHU A;  2Y5B A;  4BS6 A;  4RKX A;  3NHE A;  3K24 A;  2J7Q C;  1PBH A;  4BS5 A;  3KWB X;  4PT5 A;  4CDC B;  3PHW A;  3F75 A;  2AS8 A;  3TMP A;  3KW9 A;  2DJG B;  2F1G A;  3AI8 A;  5CHT A;  4M0W A;  1STF E;  1AIM A;  2E02 A;  3PRM A;  4KLB A;  1MHW A;  4HWY A;  1M6D A;  3BWK A;  3KWZ A;  2DCC A;  5EF4 A;  2R9M A;  3KFQ A;  2B1N A;  3U8E A;  2XU3 A;  4P16 A;  3MP2 A;  2DCA A;  4WUR A;  4OEM A;  1Q6K A;  2WBF X;  1ME3 A;  2FYE A;  3P5X A;  4D8I A;  5EZS A;  2DCD A;  2H7J A;  5E6J A;  2G7Y A;  2JQG R;  1QXP A;  2PRE A;  4YYW A;  1U9V A;  3CBJ A;  5JH3 A;  1BGO A;  1CSB B;  3B21 A;  3HHA A;  2YJC A;  1MEG A;  4QH6 A;  1PCI A;  4I04 A;  3BC3 A;  1NB3 A;  4MI7 A;  2DC8 A;  1HUC B;  1CPJ A;  1CS8 A;  2HWK A;  5JA7 A;  3KKU A;  1PPP A;  1PPD A;  3S3R A;  3ZUA A;  4FIP A;  5F02 A;  7PCK A;  1TLO A;  3H7D A;  4K7C A;  2E00 A;  1SP4 B;  2P86 A;  3H89 A;  2ACT A;  3PBH A;  2NQI A;  2HH5 A;  3PT2 A;  2BDZ A;  2BTW A;  1CQD A;  1ZCM A;  3W31 A;  1PIP A;  2HHN A;  1TU6 A;  3QT4 A;  4I05 A;  1EWM A;  2R9O A;  2O6X A;  4RF1 A;  4XR7 A;  2Z84 A;  3OVX A;  4D8E A;  2DJF B;  4OVZ B;  1YK7 A;  2OP3 A;  2DCB A;  1FH0 A;  5CHV A;  1S4V A;  1MIR A;  3C9E A;  1U5I A;  2R9N A;  2NQA A;  4CDF B;  1Y4H A;  3BY4 A;  3ERV A;  1DEU A;  3PHU A;  1GCB A;  4XZX A;  1F2B A;  1NLJ A;  2DZZ A;  4ZUX U;  4BOU A;  4BOS A;  1PPO A;  3QSD A;  4RF0 A;  2XU5 A;  2AYO A;  3WXE A;  1KHQ A;  5EGW A;  1DF0 A;  4FJC A;  2AGA A;  3BOW A;  4OW0 A;  4AXL A;  3BCN A;  4DMX A;  3BB7 A;  2E03 A;  3WXF A;  4W4U A;  2E01 A;  4D8B A;  5CVN B;  4XUI A;  4Q8G A;  3O65 A;  4MZS A;  1BQI A;  2FO5 A;  3PDF A;  8PCH A;  3CH2 X;  1UKF A;  4QRX A;  2YJB A;  1CB5 A;  3PW3 A;  3DF0 A;  2VHS A;  2ATO A;  3MJ5 A;  4IP3 A;  1F2A A;  3LFY A;  3P5W A;  3RVX A;  3S3Q A;  2FT2 A;  4BOQ A;  1EF7 A;  3PNR A;  1DKI A;  2G8E A;  3B79 A;  3E9S A;  2HD5 A;  2IPP B;  2XU1 A;  3PHX A;  1QOL A;  3K8U A;  1ITO A;  4PAD A;  1NL6 A;  2AYN A;  3PSE A;  4HXD B;  2ARY A;  1AEC A;  1Y08 A; 
#chains in the Genus database with same CATH homology
 4AXM A;  1VSN A;  4X6H A;  2F7D A;  2NQG A;  4W5C A;  1YK8 A;  4PP1 A;  4CDE B;  1CTE A;  3USV A;  2G8J A;  2YJ9 A;  1GLO A;  1POP A;  2JQF R;  3H8C A;  4X6I A;  3P5U A;  4I07 A;  2R6N A;  1PAD A;  3LXS A;  1U9X A;  1MS6 A;  4FK5 A;  4P6G A;  1EWP A;  2PBH A;  1AU0 A;  3E1Z B;  4DMY A;  1CV8 A;  1MEM A;  3CBK A;  1THE A;  3IV2 A;  2DC9 A;  2FRQ A;  4BSQ A;  4C5P A;  2CIO A;  2XU4 A;  4WA6 A;  1O0E A;  3TNX A;  1KXR A;  4YVA A;  3P5V A;  2AUZ A;  2AU1 A;  4QBB A;  2VFB A;  4X6J A;  3RVV A;  3KSE A;  1MDW A;  3HWN A;  9PAP A;  4CDD B;  1VJV A;  2R9F A;  1ICF A;  3BPF A;  3H8B A;  3MTN A;  3N3K A;  1CVZ A;  5FPW A;  3OF9 A;  4G54 A;  4RY2 A;  2NQD B;  3M99 A;  3MHS A;  2C0Y A;  1W6F A;  2FUD A;  5PAD A;  2PNS A;  3I3T A;  2HXZ A;  1QMY A;  1AYU A;  1PPN A;  4YV8 A;  2VHF A;  2DC6 A;  1AU2 A;  5J94 A;  5K16 A;  1AYW A;  3D9W A;  1JQP A;  3IMA A;  3F5V A;  3V6E A;  4W5B A;  2G6D A;  1AU3 A;  1U9Q X;  1SNK A;  1YT7 A;  2IBI A;  3BPM A;  3O1G A;  4N8W A;  2FQ9 A;  4QRV A;  2PAD A;  4QRG A;  3OIS A;  3QJ3 A;  1GEC E;  4YYQ A;  1BY8 A;  1AU4 A;  2P7U A;  2FTD A;  3KX1 A;  4PP2 E;  2P0R A;  3K9M A;  3GCB A;  4OEL A;  4BQV A;  1GMY A;  2AUX A;  1IWD A;  3IOQ A;  1BP4 A;  1YAL A;  3HHI A;  1KFX L;  1ZIV A;  1NQC A;  2B1M A;  2CB5 A;  2OZ2 A;  1EWO A;  4YYS A;  3N4C A;  2YJ8 A;  1ATK A;  1A6R A;  1U9W A;  5CVM A;  1PE6 A;  2OUL A;  3MHH A;  1AYV A;  2AIM A;  2Y6E A;  1PXV A;  3MOR A;  1QDQ A;  2FRA A;  1F2C A;  2R9C A;  3LTW A;  3IEJ A;  1YVB A;  4N4Z A;  3N3G A;  3CH3 X;  1CJL A;  6PAD A;  1TL9 A;  2DZY A;  4YYR A;  2BDL A;  4MSX A;  2DC7 A;  4N79 A;  1X9Y A;  4Q8H A;  1F29 A;  3RVW A;  3O0U A;  4YYU A;  4B55 A;  5CVO B;  3OVZ A;  3IHP A;  4NV7 A;  1KFU L;  4P6E A;  3V6C A;  1EWL A;  3OF8 A;  3I06 A;  1NPZ A;  3IUT A;  2AVW A;  4PI3 A;  4CZW A;  3H6S A;  5A24 A;  1NB5 A;  1XKG A;  4MZO A;  2GFO A;  3D6S A;  2YJ2 A;  1K3B B;  1ME4 A;  3WXG A;  3HD3 A;  1KHP A;  4YYV A;  4BPV A;  2GHU A;  2Y5B A;  4BS6 A;  1GX3 A;  3NHE A;  3K24 A;  1PBH A;  4BS5 A;  3KWB X;  4CDC B;  3F75 A;  2AS8 A;  3KW9 A;  2DJG B;  2F1G A;  3AI8 A;  5CHT A;  1STF E;  1AIM A;  2E02 A;  4KLB A;  1MHW A;  4HWY A;  1M6D A;  3BWK A;  3KWZ A;  2DCC A;  5EF4 A;  2R9M A;  3KFQ A;  2B1N A;  3U8E A;  2XU3 A;  2DCA A;  4OEM A;  1Q6K A;  2WBF X;  1ME3 A;  2FYE A;  3P5X A;  2DCD A;  2H7J A;  2G7Y A;  2JQG R;  1QXP A;  2PRE A;  4YYW A;  1U9V A;  3CBJ A;  5JH3 A;  1BGO A;  1CSB B;  3HHA A;  2YJC A;  1MEG A;  4QH6 A;  1PCI A;  4I04 A;  3BC3 A;  1NB3 A;  2DC8 A;  1HUC B;  1CPJ A;  1CS8 A;  5JA7 A;  3KKU A;  1PPP A;  1PPD A;  3S3R A;  3ZUA A;  4FIP A;  5F02 A;  2VFC A;  7PCK A;  1TLO A;  4K7C A;  3H7D A;  2E00 A;  1SP4 B;  2P86 A;  3H89 A;  2ACT A;  3PBH A;  2NQI A;  2HH5 A;  2BDZ A;  1CQD A;  1ZCM A;  1PIP A;  2HHN A;  1TU6 A;  3QT4 A;  4I05 A;  1EWM A;  2R9O A;  2O6X A;  4XR7 A;  3OVX A;  2DJF B;  1YK7 A;  2OP3 A;  2DCB A;  1FH0 A;  5CHV A;  1S4V A;  1MIR A;  3C9E A;  1U5I A;  2R9N A;  2NQA A;  4CDF B;  1Y4H A;  2BSZ A;  3ERV A;  1DEU A;  1GCB A;  1F2B A;  1NLJ A;  2DZZ A;  4ZUX U;  1PPO A;  3QSD A;  2XU5 A;  2AYO A;  3WXE A;  1KHQ A;  5EGW A;  1DF0 A;  4FJC A;  3BOW A;  4AXL A;  3BCN A;  4GUZ A;  4DMX A;  2E03 A;  3WXF A;  1E2T A;  4W4U A;  2E01 A;  5CVN B;  4XUI A;  4Q8G A;  4MZS A;  1BQI A;  2FO5 A;  3PDF A;  8PCH A;  3CH2 X;  4QRX A;  2YJB A;  1CB5 A;  3PW3 A;  4BGF A;  3DF0 A;  2VHS A;  2ATO A;  1F2A A;  3LFY A;  3P5W A;  3RVX A;  3S3Q A;  2FT2 A;  1EF7 A;  3PNR A;  1W5R A;  2G8E A;  3B79 A;  2HD5 A;  2IPP B;  2XU1 A;  1QOL A;  3K8U A;  1W4T A;  1ITO A;  4PAD A;  1NL6 A;  4NV8 A;  2AYN A;  2ARY A;  1AEC A;  1Y08 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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