3HHAA

Crystal structure of cathepsin l in complex with az12878478
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
220
structure length
220
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dipeptidyl nitrile inhibitors of Cathepsin L.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Cathepsin L1
total genus 70
structure length 220
sequence length 220
chains with identical sequence B, C, D
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2009-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3hhaA00
3BWKA 3CBKA 2PADA 4YVAA 5CHVA 9PAPA 2PBHA 2HH5A 1AIMA 1TU6A 3WXGA 2R9FA 2XU1A 4MSXA 4CZWA 3IMAA 3QSDA 1NPZA 1CQDA 1ME3A 1GLOA 3TNXA 3PNRA 1EF7A 1MHWA 2FT2A 1HUCB 2E02A 2E01A 1IWDA 4WA6A 1KHPA 2G7YA 3QT4A 2AYNA 1ITOA 3MHSA 4X6JA 1BGOA 1THEA 1EWPA 4XUIA 4AXLA 3WXFA 2ARYA 3KW9A 4I05A 2DC8A 1ATKA 2JQFR 5FPWA 1AYUA 1CTEA 2AUXA 3O1GA 3P5WA 4YV8A 3O0UA 2GFOA 3H8CA 2FTDA 3OISA 4OEMA 3F75A 1A6RA 1TL9A 1VSNA 4CDDB 2FYEA 2AVWA 4P6GA 2DCCA 4RY2A 1YVBA 3BOWA 3MORA 5K16A 1PIPA 3OVZA 3PDFA 3K8UA 3V6CA 4I04A 4PADA 3KX1A 2WBFX 4KLBA 2E03A 1K3BB 4P6EA 2R9MA 1MDWA 4X6IA 4N4ZA 3BPMA 1BY8A 2O6XA 1EWOA 4PP2E 1F2BA 3H8BA 3M99A 1YALA 1F2CA 3IV2A 3ERVA 2YJ8A 5CVMA 3BC3A 1SNKA 2P86A 4XR7A 2XU5A 1NB5A 5J94A 5A24A 2P0RA 3OF8A 2B1MA 4CDFB 1ZIVA 1U9QX 1S4VA 1M6DA 2AU1A 1JQPA 2R9OA 2IBIA 1AU3A 2DC6A 3BPFA 1PPPA 4BQVA 2JQGR 1AU2A 1X9YA 2OP3A 4FK5A 3AI8A 3OVXA 3LFYA 2AIMA 1KHQA 2H7JA 2R6NA 1Y08A 4QBBA 2PNSA 5CHTA 2YJ9A 1AU0A 1AU4A 4QRGA 1PPOA 4AXMA 1QXPA 2DCAA 3S3RA 4CDEB 2B1NA 3DF0A 2VHSA 2DCBA 2P7UA 3E1ZB 1SP4B 1NLJA 2NQGA 2HXZA 2DCDA 3V6EA 4BSQA 1DEUA 2AUZA 4Q8GA 1EWLA 2OZ2A 3HHIA 2NQDB 3USVA 3I3TA 2DJFB 2Y5BA 4K7CA 3ZUAA 5CVOB 2BDLA 3RVWA 1U9XA 3H7DA 2YJCA 3P5VA 2G8JA 2XU3A 1ZCMA 2YJ2A 3MHHA 1PBHA 2BDZA 4Q8HA 3KKUA 3RVXA 2DZYA 1ICFA 1U5IA 4OELA 2GHUA 1CB5A 7PCKA 2FQ9A 1FH0A 2G8EA 1KFXL 1MEGA 1BQIA 4MZOA 5F02A 1PE6A 2AYOA 3BCNA 1PXVA 1PADA 1BP4A 1GECE 1MIRA 2HHNA 4W4UA 4W5BA 3IHPA 4FIPA 1STFE 4PP1A 4DMYA 2G6DA 4YYRA 2DC7A 4DMXA 1AYWA 1PPDA 1NB3A 1KFUL 2DC9A 3OF9A 4YYUA 1F2AA 3D6SA 1XKGA 1CV8A 1Y4HA 3QJ3A 3H89A 4QH6A 3MTNA 5PADA 4BS5A 6PADA 4BPVA 4N8WA 4YYWA 4G54A 4FJCA 1GMYA 1AECA 2XU4A 8PCHA 1MEMA 1GCBA 5EF4A 1YK7A 2C0YA 4CDCB 2NQIA 2YJBA 3LXSA 3P5UA 4QRXA 3NHEA 3N3KA 1O0EA 1AYVA 2DZZA 2HD5A 3N4CA 1PPNA 1NQCA 3KWBX 1QDQA 3K9MA 1YT7A 3KWZA 1VJVA 3IOQA 1TLOA 2FO5A 2E00A 4YYQA 1CPJA 1CS8A 2ACTA 4X6HA 3WXEA 4YYSA 2DJGB 3KSEA 2F1GA 2NQAA 2FRAA 2FUDA 4HWYA 5CVNB 3S3QA 1CJLA 4MZSA 3PBHA 3CH3X 4PI3A 2F7DA 3C9EA 3K24A 5JA7A 2IPPB 2VHFA 1DF0A 4BS6A 3HD3A 3I06A 3N3GA 2OULA 1YK8A 2Y6EA 2R9CA 2R9NA 1KXRA 3GCBA 2FRQA 1U9WA 3IEJA 4W5CA 3RVVA 1ME4A 3F5VA 1CSBB 1MS6A 3KFQA 4YYVA 3P5XA 5JH3A 2AS8A 5EGWA 3HHAA 4ZUXU 1U9VA 1NL6A 2CB5A 3B79A 1QMYA 4I07A 1QOLA 3U8EA 1EWMA 1Q6KA 1F29A 4N79A 2ATOA 2PREA 1PCIA 1POPA 1CVZA 3CH2X 3H6SA 3HWNA 4QRVA 3CBJA 3PW3A 2CIOA 3IUTA
chains in the Genus database with same CATH superfamily
3BWKA 3CBKA 2PADA 4YVAA 2JTCA 5CHVA 9PAPA 2PBHA 1PVJA 2HH5A 4D8EA 1AIMA 1TU6A 3WXGA 4GUAA 2R9FA 2XU1A 4MSXA 4CZWA 3IMAA 3QSDA 1NPZA 2J7QC 1CQDA 1ME3A 1GLOA 3TNXA 3PNRA 1EF7A 1MHWA 5EZQA 2FT2A 1HUCB 2E02A 2E01A 1IWDA 3MTVA 4BOUA 4WA6A 1KHPA 2G7YA 3QT4A 2AYNA 1ITOA 3MHSA 4X6JA 1BGOA 1THEA 1EWPA 4XUIA 4AXLA 3WXFA 2ARYA 2BTWB 3KW9A 4I05A 2DC8A 4RNAA 1ATKA 2JQFR 5FPWA 1AYUA 1CTEA 2AUXA 4BOSA 2BU3A 3ZNHA 3O1GA 3BY4A 3P5WA 4YV8A 3O0UA 2GFOA 2JRIA 3H8CA 2FTDA 3OISA 4OEMA 3F75A 1A6RA 1TL9A 1VSNA 4CDDB 2FYEA 2AVWA 4P6GA 2DCCA 4RY2A 1YVBA 3BOWA 3MORA 5K16A 1DKIA 1PIPA 3OVZA 3PDFA 3K8UA 4IP3A 3V6CA 4I04A 4PADA 3KX1A 4RKXA 2WBFX 4KLBA 2E03A 1K3BB 4P6EA 2R9MA 1MDWA 4X6IA 4N4ZA 3BPMA 1BY8A 2O6XA 1EWOA 4PP2E 1F2BA 3H8BA 3RNVA 3M99A 1YALA 1F2CA 3IV2A 3ERVA 2YJ8A 5CVMA 3BC3A 1SNKA 2P86A 4OVZA 4XR7A 2XU5A 1NB5A 5J94A 5A24A 3W31A 2P0RA 3OF8A 2B1MA 4RF0A 4CDFB 1ZIVA 5E6JA 1U9QX 1S4VA 1M6DA 2AU1A 1JQPA 2R9OA 2IBIA 1AU3A 2DC6A 3BPFA 1PPPA 4BQVA 2JQGR 1AU2A 1X9YA 2OP3A 4FK5A 5JZEA 3AI8A 3OVXA 3LFYA 2AIMA 1KHQA 2H7JA 3W30A 2R6NA 1Y08A 4QBBA 2PNSA 5CHTA 2YJ9A 1AU0A 1AU4A 4IUMA 4QRGA 1PPOA 4AXMA 1QXPA 2DCAA 3S3RA 4CDEB 3PRMA 2B1NA 2VHSA 1UKFA 3DF0A 2DCBA 2P7UA 4WURA 3E1ZB 1SP4B 4BOQA 1NLJA 2NQGA 2HXZA 3PHWA 2DCDA 3MP2A 3V6EA 4BSQA 1DEUA 2AUZA 3PRPA 4P16A 4Q8GA 1EWLA 2DOSA 2OZ2A 3HHIA 2NQDB 3USVA 3I3TA 3E9SA 2DJFB 4BOZA 2HWKA 2Y5BA 3OQCA 4K7CA 3ZUAA 5CVOB 2BDLA 3RVWA 3IFUA 1U9XA 3BB7A 3H7DA 2YJCA 3P5VA 2G8JA 4ZTBA 2XU3A 1ZCMA 2FE8A 2YJ2A 4BOPA 3MHHA 1PBHA 2BDZA 4Q8HA 3KKUA 4MI7A 3RVXA 2DZYA 3PHXA 1ICFA 4XZXA 1U5IA 4OELA 2GHUA 1CB5A 7PCKA 2FQ9A 1FH0A 2G8EA 1KFXL 2J7QA 1MEGA 1BQIA 4MZOA 5F02A 1PE6A 2AGAA 2AYOA 3BCNA 3TRKA 1PXVA 1PADA 1BP4A 1GECE 1MIRA 2HHNA 4W4UA 4W5BA 3IHPA 4FIPA 1STFE 4PP1A 4DMYA 2G6DA 4YYRA 2DC7A 4MM3B 4DMXA 1AYWA 1PPDA 1NB3A 1KFUL 2DC9A 3OF9A 4YYUA 2BTWA 1F2AA 3D6SA 1XKGA 1CV8A 1Y4HA 3QJ3A 3H89A 4QH6A 3MTNA 5PADA 4BS5A 6PADA 4BPVA 4N8WA 4YYWA 4G54A 4FJCA 1GMYA 1AECA 2XU4A 8PCHA 1MEMA 1GCBA 4D8BA 5EF4A 1YK7A 2C0YA 4CDCB 5KO3A 2NQIA 2YJBA 4RF1A 3LXSA 3P5UA 5EZSA 4QRXA 3NHEA 3N3KA 1O0EA 1AYVA 2DZZA 2HD5A 3N4CA 1PPNA 1NQCA 3KWBX 1QDQA 3K9MA 1YT7A 3KWZA 3PSEA 4M0WA 3TMPA 1VJVA 3IOQA 3C0RA 1TLOA 2FO5A 2E00A 4YYQA 2UZJA 1CPJA 1CS8A 2ACTA 4X6HA 3WXEA 4YYSA 2DJGB 3KSEA 3PHUA 2F1GA 2NQAA 2FRAA 2FUDA 4HWYA 5CVNB 4HXDB 3S3QA 1CJLA 4MZSA 4OVZB 4PT5A 3PBHA 3CH3X 4R3DA 3MJ5A 4PI3A 2F7DA 3C9EA 3K24A 5JA7A 4REZA 2IPPB 2VHFA 1DF0A 4BS6A 3HD3A 3I06A 2Z84A 3N3GA 2OULA 3PT2A 1YK8A 2Y6EA 2R9CA 2R9NA 1KXRA 3GCBA 2FRQA 4OW0A 1U9WA 3IEJA 4W5CA 3RVVA 4A5UA 1ME4A 3F5VA 1CSBB 3B21A 1MS6A 3KFQA 4D8IA 4YYVA 3P5XA 5JH3A 2AS8A 5EGWA 3HHAA 4ZUXU 1U9VA 1NL6A 2CB5A 3B79A 1QMYA 3O65A 1QOLA 4I07A 3U8EA 1EWMA 1Q6KA 3BBAA 1F29A 4N79A 2ATOA 2PREA 1PCIA 1POPA 1CVZA 3CH2X 3H6SA 1YZBA 3HWNA 4QRVA 3CBJA 3PW3A 2CIOA 3IUTA
chains in the Genus database with same CATH topology
3BWKA 3CBKA 2PADA 2BSZA 4YVAA 5CHVA 9PAPA 2PBHA 2HH5A 1AIMA 1TU6A 3WXGA 2R9FA 2XU1A 4MSXA 4CZWA 3IMAA 3QSDA 1NPZA 1CQDA 1ME3A 1GLOA 3TNXA 3PNRA 1EF7A 1MHWA 4C5PA 2FT2A 1HUCB 2E02A 2E01A 1IWDA 4WA6A 1KHPA 2G7YA 3QT4A 2AYNA 1ITOA 3MHSA 4X6JA 1BGOA 1THEA 1EWPA 4XUIA 4AXLA 3WXFA 2ARYA 3KW9A 4I05A 2DC8A 4B55A 1ATKA 2JQFR 5FPWA 1AYUA 1CTEA 2AUXA 2VFBA 3LTWA 3O1GA 3P5WA 4YV8A 3O0UA 2GFOA 4BGFA 3H8CA 2FTDA 2VFCA 3OISA 4OEMA 3F75A 1A6RA 1TL9A 1VSNA 4CDDB 2FYEA 2AVWA 4P6GA 2DCCA 4RY2A 1YVBA 3BOWA 3MORA 5K16A 1PIPA 3OVZA 3PDFA 3K8UA 3V6CA 4I04A 4PADA 3KX1A 1GX3A 2WBFX 4KLBA 2E03A 1K3BB 4P6EA 2R9MA 1MDWA 4X6IA 4N4ZA 3BPMA 1BY8A 2O6XA 1EWOA 4PP2E 1F2BA 3H8BA 3M99A 1YALA 1F2CA 3IV2A 3ERVA 2YJ8A 4NV7A 5CVMA 3BC3A 1SNKA 2P86A 4XR7A 2XU5A 1NB5A 5J94A 5A24A 2P0RA 3OF8A 2B1MA 4CDFB 1ZIVA 1U9QX 1S4VA 1M6DA 2AU1A 1JQPA 2R9OA 2IBIA 1AU3A 2DC6A 3BPFA 1PPPA 4BQVA 2JQGR 1AU2A 1X9YA 2OP3A 4FK5A 3AI8A 3OVXA 3LFYA 2AIMA 1KHQA 2H7JA 2R6NA 1Y08A 4QBBA 2PNSA 5CHTA 2YJ9A 3D9WA 1AU0A 1AU4A 4QRGA 1PPOA 4AXMA 1QXPA 2DCAA 3S3RA 4CDEB 2B1NA 3DF0A 2VHSA 2DCBA 2P7UA 3E1ZB 1SP4B 1NLJA 2NQGA 2HXZA 2DCDA 3V6EA 4BSQA 3IUTA 1DEUA 2AUZA 4NV8A 4Q8GA 1EWLA 2OZ2A 3HHIA 2NQDB 3USVA 3I3TA 2DJFB 2Y5BA 4K7CA 3ZUAA 5CVOB 2BDLA 3RVWA 1U9XA 3H7DA 2YJCA 3P5VA 2G8JA 2XU3A 1ZCMA 2YJ2A 3MHHA 1PBHA 2BDZA 4Q8HA 3KKUA 3RVXA 2DZYA 1ICFA 1U5IA 4OELA 2GHUA 1CB5A 7PCKA 2FQ9A 1FH0A 2G8EA 1KFXL 1MEGA 1BQIA 4MZOA 5F02A 1PE6A 2AYOA 3BCNA 1PXVA 1PADA 1BP4A 1GECE 1MIRA 2HHNA 4W4UA 4W5BA 3IHPA 4FIPA 1E2TA 1STFE 4PP1A 4DMYA 2G6DA 4YYRA 2DC7A 4DMXA 1AYWA 1PPDA 1NB3A 1KFUL 1W6FA 2DC9A 3OF9A 4YYUA 1F2AA 3D6SA 1XKGA 1CV8A 1Y4HA 3QJ3A 3H89A 4QH6A 3MTNA 5PADA 4BS5A 6PADA 4BPVA 4N8WA 4YYWA 4G54A 4FJCA 1GMYA 1AECA 2XU4A 8PCHA 1MEMA 1GCBA 5EF4A 1YK7A 2C0YA 4CDCB 2NQIA 2YJBA 3LXSA 3P5UA 4QRXA 3NHEA 3N3KA 1O0EA 1AYVA 2DZZA 2HD5A 1W4TA 3N4CA 1PPNA 1NQCA 3KWBX 1QDQA 3K9MA 1YT7A 3KWZA 1VJVA 3IOQA 1TLOA 2FO5A 2E00A 4YYQA 1CPJA 1CS8A 2ACTA 4X6HA 3WXEA 4YYSA 1W5RA 2DJGB 3KSEA 2F1GA 2NQAA 2FRAA 2FUDA 4HWYA 5CVNB 3S3QA 1CJLA 4MZSA 3PBHA 3CH3X 4PI3A 2F7DA 3C9EA 3K24A 5JA7A 2IPPB 2VHFA 1DF0A 4BS6A 3HD3A 3I06A 3N3GA 2OULA 1YK8A 2Y6EA 2R9CA 2R9NA 1KXRA 3GCBA 2FRQA 1U9WA 3IEJA 4W5CA 3RVVA 1ME4A 3F5VA 1CSBB 1MS6A 3KFQA 4YYVA 3P5XA 5JH3A 2AS8A 5EGWA 3HHAA 4ZUXU 1U9VA 1NL6A 2CB5A 3B79A 1QMYA 4I07A 1QOLA 3U8EA 1EWMA 1Q6KA 1F29A 4N79A 2ATOA 2PREA 1PCIA 1POPA 1CVZA 3CH2X 3H6SA 3HWNA 4QRVA 3CBJA 3PW3A 2CIOA 4GUZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BWK A;  3CBK A;  2PAD A;  4YVA A;  5CHV A;  9PAP A;  2PBH A;  2HH5 A;  1AIM A;  1TU6 A;  3WXG A;  2R9F A;  2XU1 A;  4MSX A;  4CZW A;  3IMA A;  3QSD A;  1NPZ A;  1CQD A;  1ME3 A;  1GLO A;  3TNX A;  3PNR A;  1EF7 A;  1MHW A;  2FT2 A;  1HUC B;  2E02 A;  2E01 A;  1IWD A;  4WA6 A;  1KHP A;  2G7Y A;  3QT4 A;  2AYN A;  1ITO A;  3MHS A;  4X6J A;  1BGO A;  1THE A;  1EWP A;  4XUI A;  4AXL A;  3WXF A;  2ARY A;  3KW9 A;  4I05 A;  2DC8 A;  1ATK A;  2JQF R;  5FPW A;  1AYU A;  1CTE A;  2AUX A;  3O1G A;  3P5W A;  4YV8 A;  3O0U A;  2GFO A;  3H8C A;  2FTD A;  3OIS A;  4OEM A;  3F75 A;  1A6R A;  1TL9 A;  1VSN A;  4CDD B;  2FYE A;  2AVW A;  4P6G A;  2DCC A;  4RY2 A;  1YVB A;  3BOW A;  3MOR A;  5K16 A;  1PIP A;  3OVZ A;  3PDF A;  3K8U A;  3V6C A;  4I04 A;  4PAD A;  3KX1 A;  2WBF X;  4KLB A;  2E03 A;  1K3B B;  4P6E A;  2R9M A;  1MDW A;  4X6I A;  4N4Z A;  3BPM A;  1BY8 A;  2O6X A;  1EWO A;  4PP2 E;  1F2B A;  3H8B A;  3M99 A;  1YAL A;  1F2C A;  3IV2 A;  3ERV A;  2YJ8 A;  5CVM A;  3BC3 A;  1SNK A;  2P86 A;  4XR7 A;  2XU5 A;  1NB5 A;  5J94 A;  5A24 A;  2P0R A;  3OF8 A;  2B1M A;  4CDF B;  1ZIV A;  1U9Q X;  1S4V A;  1M6D A;  2AU1 A;  1JQP A;  2R9O A;  2IBI A;  1AU3 A;  2DC6 A;  3BPF A;  1PPP A;  4BQV A;  2JQG R;  1AU2 A;  1X9Y A;  2OP3 A;  4FK5 A;  3AI8 A;  3OVX A;  3LFY A;  2AIM A;  1KHQ A;  2H7J A;  2R6N A;  1Y08 A;  4QBB A;  2PNS A;  5CHT A;  2YJ9 A;  1AU0 A;  1AU4 A;  4QRG A;  1PPO A;  4AXM A;  1QXP A;  2DCA A;  3S3R A;  4CDE B;  2B1N A;  3DF0 A;  2VHS A;  2DCB A;  2P7U A;  3E1Z B;  1SP4 B;  1NLJ A;  2NQG A;  2HXZ A;  2DCD A;  3V6E A;  4BSQ A;  1DEU A;  2AUZ A;  4Q8G A;  1EWL A;  2OZ2 A;  3HHI A;  2NQD B;  3USV A;  3I3T A;  2DJF B;  2Y5B A;  4K7C A;  3ZUA A;  5CVO B;  2BDL A;  3RVW A;  1U9X A;  3H7D A;  2YJC A;  3P5V A;  2G8J A;  2XU3 A;  1ZCM A;  2YJ2 A;  3MHH A;  1PBH A;  2BDZ A;  4Q8H A;  3KKU A;  3RVX A;  2DZY A;  1ICF A;  1U5I A;  4OEL A;  2GHU A;  1CB5 A;  7PCK A;  2FQ9 A;  1FH0 A;  2G8E A;  1KFX L;  1MEG A;  1BQI A;  4MZO A;  5F02 A;  1PE6 A;  2AYO A;  3BCN A;  1PXV A;  1PAD A;  1BP4 A;  1GEC E;  1MIR A;  2HHN A;  4W4U A;  4W5B A;  3IHP A;  4FIP A;  1STF E;  4PP1 A;  4DMY A;  2G6D A;  4YYR A;  2DC7 A;  4DMX A;  1AYW A;  1PPD A;  1NB3 A;  1KFU L;  2DC9 A;  3OF9 A;  4YYU A;  1F2A A;  3D6S A;  1XKG A;  1CV8 A;  1Y4H A;  3QJ3 A;  3H89 A;  4QH6 A;  3MTN A;  5PAD A;  4BS5 A;  6PAD A;  4BPV A;  4N8W A;  4YYW A;  4G54 A;  4FJC A;  1GMY A;  1AEC A;  2XU4 A;  8PCH A;  1MEM A;  1GCB A;  5EF4 A;  1YK7 A;  2C0Y A;  4CDC B;  2NQI A;  2YJB A;  3LXS A;  3P5U A;  4QRX A;  3NHE A;  3N3K A;  1O0E A;  1AYV A;  2DZZ A;  2HD5 A;  3N4C A;  1PPN A;  1NQC A;  3KWB X;  1QDQ A;  3K9M A;  1YT7 A;  3KWZ A;  1VJV A;  3IOQ A;  1TLO A;  2FO5 A;  2E00 A;  4YYQ A;  1CPJ A;  1CS8 A;  2ACT A;  4X6H A;  3WXE A;  4YYS A;  2DJG B;  3KSE A;  2F1G A;  2NQA A;  2FRA A;  2FUD A;  4HWY A;  5CVN B;  3S3Q A;  1CJL A;  4MZS A;  3PBH A;  3CH3 X;  4PI3 A;  2F7D A;  3C9E A;  3K24 A;  5JA7 A;  2IPP B;  2VHF A;  1DF0 A;  4BS6 A;  3HD3 A;  3I06 A;  3N3G A;  2OUL A;  1YK8 A;  2Y6E A;  2R9C A;  2R9N A;  1KXR A;  3GCB A;  2FRQ A;  1U9W A;  3IEJ A;  4W5C A;  3RVV A;  1ME4 A;  3F5V A;  1CSB B;  1MS6 A;  3KFQ A;  4YYV A;  3P5X A;  5JH3 A;  2AS8 A;  5EGW A;  3HHA A;  4ZUX U;  1U9V A;  1NL6 A;  2CB5 A;  3B79 A;  1QMY A;  4I07 A;  1QOL A;  3U8E A;  1EWM A;  1Q6K A;  1F29 A;  4N79 A;  2ATO A;  2PRE A;  1PCI A;  1POP A;  1CVZ A;  3CH2 X;  3H6S A;  3HWN A;  4QRV A;  3CBJ A;  3PW3 A;  2CIO A;  3IUT A; 
#chains in the Genus database with same CATH topology
 3BWK A;  3CBK A;  2PAD A;  4YVA A;  2JTC A;  5CHV A;  9PAP A;  2PBH A;  1PVJ A;  2HH5 A;  4D8E A;  1AIM A;  1TU6 A;  3WXG A;  4GUA A;  2R9F A;  2XU1 A;  4MSX A;  4CZW A;  3IMA A;  3QSD A;  1NPZ A;  2J7Q C;  1CQD A;  1ME3 A;  1GLO A;  3TNX A;  3PNR A;  1EF7 A;  1MHW A;  5EZQ A;  2FT2 A;  1HUC B;  2E02 A;  2E01 A;  1IWD A;  3MTV A;  4BOU A;  4WA6 A;  1KHP A;  2G7Y A;  3QT4 A;  2AYN A;  1ITO A;  3MHS A;  4X6J A;  1BGO A;  1THE A;  1EWP A;  4XUI A;  4AXL A;  3WXF A;  2ARY A;  2BTW B;  3KW9 A;  4I05 A;  2DC8 A;  4RNA A;  1ATK A;  2JQF R;  5FPW A;  1AYU A;  1CTE A;  2AUX A;  4BOS A;  2BU3 A;  3ZNH A;  3O1G A;  3BY4 A;  3P5W A;  4YV8 A;  3O0U A;  2GFO A;  2JRI A;  3H8C A;  2FTD A;  3OIS A;  4OEM A;  3F75 A;  1A6R A;  1TL9 A;  1VSN A;  4CDD B;  2FYE A;  2AVW A;  4P6G A;  2DCC A;  4RY2 A;  1YVB A;  3BOW A;  3MOR A;  5K16 A;  1DKI A;  1PIP A;  3OVZ A;  3PDF A;  3K8U A;  4IP3 A;  3V6C A;  4I04 A;  4PAD A;  3KX1 A;  4RKX A;  2WBF X;  4KLB A;  2E03 A;  1K3B B;  4P6E A;  2R9M A;  1MDW A;  4X6I A;  4N4Z A;  3BPM A;  1BY8 A;  2O6X A;  1EWO A;  4PP2 E;  1F2B A;  3H8B A;  3RNV A;  3M99 A;  1YAL A;  1F2C A;  3IV2 A;  3ERV A;  2YJ8 A;  5CVM A;  3BC3 A;  1SNK A;  2P86 A;  4OVZ A;  4XR7 A;  2XU5 A;  1NB5 A;  5J94 A;  5A24 A;  3W31 A;  2P0R A;  3OF8 A;  2B1M A;  4RF0 A;  4CDF B;  1ZIV A;  5E6J A;  1U9Q X;  1S4V A;  1M6D A;  2AU1 A;  1JQP A;  2R9O A;  2IBI A;  1AU3 A;  2DC6 A;  3BPF A;  1PPP A;  4BQV A;  2JQG R;  1AU2 A;  1X9Y A;  2OP3 A;  4FK5 A;  5JZE A;  3AI8 A;  3OVX A;  3LFY A;  2AIM A;  1KHQ A;  2H7J A;  3W30 A;  2R6N A;  1Y08 A;  4QBB A;  2PNS A;  5CHT A;  2YJ9 A;  1AU0 A;  1AU4 A;  4IUM A;  4QRG A;  1PPO A;  4AXM A;  1QXP A;  2DCA A;  3S3R A;  4CDE B;  3PRM A;  2B1N A;  2VHS A;  1UKF A;  3DF0 A;  2DCB A;  2P7U A;  4WUR A;  3E1Z B;  1SP4 B;  4BOQ A;  1NLJ A;  2NQG A;  2HXZ A;  3PHW A;  2DCD A;  3MP2 A;  3V6E A;  4BSQ A;  1DEU A;  2AUZ A;  3PRP A;  4P16 A;  4Q8G A;  1EWL A;  2DOS A;  2OZ2 A;  3HHI A;  2NQD B;  3USV A;  3I3T A;  3E9S A;  2DJF B;  4BOZ A;  2HWK A;  2Y5B A;  3OQC A;  4K7C A;  3ZUA A;  5CVO B;  2BDL A;  3RVW A;  3IFU A;  1U9X A;  3BB7 A;  3H7D A;  2YJC A;  3P5V A;  2G8J A;  4ZTB A;  2XU3 A;  1ZCM A;  2FE8 A;  2YJ2 A;  4BOP A;  3MHH A;  1PBH A;  2BDZ A;  4Q8H A;  3KKU A;  4MI7 A;  3RVX A;  2DZY A;  3PHX A;  1ICF A;  4XZX A;  1U5I A;  4OEL A;  2GHU A;  1CB5 A;  7PCK A;  2FQ9 A;  1FH0 A;  2G8E A;  1KFX L;  2J7Q A;  1MEG A;  1BQI A;  4MZO A;  5F02 A;  1PE6 A;  2AGA A;  2AYO A;  3BCN A;  3TRK A;  1PXV A;  1PAD A;  1BP4 A;  1GEC E;  1MIR A;  2HHN A;  4W4U A;  4W5B A;  3IHP A;  4FIP A;  1STF E;  4PP1 A;  4DMY A;  2G6D A;  4YYR A;  2DC7 A;  4MM3 B;  4DMX A;  1AYW A;  1PPD A;  1NB3 A;  1KFU L;  2DC9 A;  3OF9 A;  4YYU A;  2BTW A;  1F2A A;  3D6S A;  1XKG A;  1CV8 A;  1Y4H A;  3QJ3 A;  3H89 A;  4QH6 A;  3MTN A;  5PAD A;  4BS5 A;  6PAD A;  4BPV A;  4N8W A;  4YYW A;  4G54 A;  4FJC A;  1GMY A;  1AEC A;  2XU4 A;  8PCH A;  1MEM A;  1GCB A;  4D8B A;  5EF4 A;  1YK7 A;  2C0Y A;  4CDC B;  5KO3 A;  2NQI A;  2YJB A;  4RF1 A;  3LXS A;  3P5U A;  5EZS A;  4QRX A;  3NHE A;  3N3K A;  1O0E A;  1AYV A;  2DZZ A;  2HD5 A;  3N4C A;  1PPN A;  1NQC A;  3KWB X;  1QDQ A;  3K9M A;  1YT7 A;  3KWZ A;  3PSE A;  4M0W A;  3TMP A;  1VJV A;  3IOQ A;  3C0R A;  1TLO A;  2FO5 A;  2E00 A;  4YYQ A;  2UZJ A;  1CPJ A;  1CS8 A;  2ACT A;  4X6H A;  3WXE A;  4YYS A;  2DJG B;  3KSE A;  3PHU A;  2F1G A;  2NQA A;  2FRA A;  2FUD A;  4HWY A;  5CVN B;  4HXD B;  3S3Q A;  1CJL A;  4MZS A;  4OVZ B;  4PT5 A;  3PBH A;  3CH3 X;  4R3D A;  3MJ5 A;  4PI3 A;  2F7D A;  3C9E A;  3K24 A;  5JA7 A;  4REZ A;  2IPP B;  2VHF A;  1DF0 A;  4BS6 A;  3HD3 A;  3I06 A;  2Z84 A;  3N3G A;  2OUL A;  3PT2 A;  1YK8 A;  2Y6E A;  2R9C A;  2R9N A;  1KXR A;  3GCB A;  2FRQ A;  4OW0 A;  1U9W A;  3IEJ A;  4W5C A;  3RVV A;  4A5U A;  1ME4 A;  3F5V A;  1CSB B;  3B21 A;  1MS6 A;  3KFQ A;  4D8I A;  4YYV A;  3P5X A;  5JH3 A;  2AS8 A;  5EGW A;  3HHA A;  4ZUX U;  1U9V A;  1NL6 A;  2CB5 A;  3B79 A;  1QMY A;  3O65 A;  1QOL A;  4I07 A;  3U8E A;  1EWM A;  1Q6K A;  3BBA A;  1F29 A;  4N79 A;  2ATO A;  2PRE A;  1PCI A;  1POP A;  1CVZ A;  3CH2 X;  3H6S A;  1YZB A;  3HWN A;  4QRV A;  3CBJ A;  3PW3 A;  2CIO A;  3IUT A; 
#chains in the Genus database with same CATH homology
 3BWK A;  3CBK A;  2PAD A;  2BSZ A;  4YVA A;  5CHV A;  9PAP A;  2PBH A;  2HH5 A;  1AIM A;  1TU6 A;  3WXG A;  2R9F A;  2XU1 A;  4MSX A;  4CZW A;  3IMA A;  3QSD A;  1NPZ A;  1CQD A;  1ME3 A;  1GLO A;  3TNX A;  3PNR A;  1EF7 A;  1MHW A;  4C5P A;  2FT2 A;  1HUC B;  2E02 A;  2E01 A;  1IWD A;  4WA6 A;  1KHP A;  2G7Y A;  3QT4 A;  2AYN A;  1ITO A;  3MHS A;  4X6J A;  1BGO A;  1THE A;  1EWP A;  4XUI A;  4AXL A;  3WXF A;  2ARY A;  3KW9 A;  4I05 A;  2DC8 A;  4B55 A;  1ATK A;  2JQF R;  5FPW A;  1AYU A;  1CTE A;  2AUX A;  2VFB A;  3LTW A;  3O1G A;  3P5W A;  4YV8 A;  3O0U A;  2GFO A;  4BGF A;  3H8C A;  2FTD A;  2VFC A;  3OIS A;  4OEM A;  3F75 A;  1A6R A;  1TL9 A;  1VSN A;  4CDD B;  2FYE A;  2AVW A;  4P6G A;  2DCC A;  4RY2 A;  1YVB A;  3BOW A;  3MOR A;  5K16 A;  1PIP A;  3OVZ A;  3PDF A;  3K8U A;  3V6C A;  4I04 A;  4PAD A;  3KX1 A;  1GX3 A;  2WBF X;  4KLB A;  2E03 A;  1K3B B;  4P6E A;  2R9M A;  1MDW A;  4X6I A;  4N4Z A;  3BPM A;  1BY8 A;  2O6X A;  1EWO A;  4PP2 E;  1F2B A;  3H8B A;  3M99 A;  1YAL A;  1F2C A;  3IV2 A;  3ERV A;  2YJ8 A;  4NV7 A;  5CVM A;  3BC3 A;  1SNK A;  2P86 A;  4XR7 A;  2XU5 A;  1NB5 A;  5J94 A;  5A24 A;  2P0R A;  3OF8 A;  2B1M A;  4CDF B;  1ZIV A;  1U9Q X;  1S4V A;  1M6D A;  2AU1 A;  1JQP A;  2R9O A;  2IBI A;  1AU3 A;  2DC6 A;  3BPF A;  1PPP A;  4BQV A;  2JQG R;  1AU2 A;  1X9Y A;  2OP3 A;  4FK5 A;  3AI8 A;  3OVX A;  3LFY A;  2AIM A;  1KHQ A;  2H7J A;  2R6N A;  1Y08 A;  4QBB A;  2PNS A;  5CHT A;  2YJ9 A;  3D9W A;  1AU0 A;  1AU4 A;  4QRG A;  1PPO A;  4AXM A;  1QXP A;  2DCA A;  3S3R A;  4CDE B;  2B1N A;  3DF0 A;  2VHS A;  2DCB A;  2P7U A;  3E1Z B;  1SP4 B;  1NLJ A;  2NQG A;  2HXZ A;  2DCD A;  3V6E A;  4BSQ A;  3IUT A;  1DEU A;  2AUZ A;  4NV8 A;  4Q8G A;  1EWL A;  2OZ2 A;  3HHI A;  2NQD B;  3USV A;  3I3T A;  2DJF B;  2Y5B A;  4K7C A;  3ZUA A;  5CVO B;  2BDL A;  3RVW A;  1U9X A;  3H7D A;  2YJC A;  3P5V A;  2G8J A;  2XU3 A;  1ZCM A;  2YJ2 A;  3MHH A;  1PBH A;  2BDZ A;  4Q8H A;  3KKU A;  3RVX A;  2DZY A;  1ICF A;  1U5I A;  4OEL A;  2GHU A;  1CB5 A;  7PCK A;  2FQ9 A;  1FH0 A;  2G8E A;  1KFX L;  1MEG A;  1BQI A;  4MZO A;  5F02 A;  1PE6 A;  2AYO A;  3BCN A;  1PXV A;  1PAD A;  1BP4 A;  1GEC E;  1MIR A;  2HHN A;  4W4U A;  4W5B A;  3IHP A;  4FIP A;  1E2T A;  1STF E;  4PP1 A;  4DMY A;  2G6D A;  4YYR A;  2DC7 A;  4DMX A;  1AYW A;  1PPD A;  1NB3 A;  1KFU L;  1W6F A;  2DC9 A;  3OF9 A;  4YYU A;  1F2A A;  3D6S A;  1XKG A;  1CV8 A;  1Y4H A;  3QJ3 A;  3H89 A;  4QH6 A;  3MTN A;  5PAD A;  4BS5 A;  6PAD A;  4BPV A;  4N8W A;  4YYW A;  4G54 A;  4FJC A;  1GMY A;  1AEC A;  2XU4 A;  8PCH A;  1MEM A;  1GCB A;  5EF4 A;  1YK7 A;  2C0Y A;  4CDC B;  2NQI A;  2YJB A;  3LXS A;  3P5U A;  4QRX A;  3NHE A;  3N3K A;  1O0E A;  1AYV A;  2DZZ A;  2HD5 A;  1W4T A;  3N4C A;  1PPN A;  1NQC A;  3KWB X;  1QDQ A;  3K9M A;  1YT7 A;  3KWZ A;  1VJV A;  3IOQ A;  1TLO A;  2FO5 A;  2E00 A;  4YYQ A;  1CPJ A;  1CS8 A;  2ACT A;  4X6H A;  3WXE A;  4YYS A;  1W5R A;  2DJG B;  3KSE A;  2F1G A;  2NQA A;  2FRA A;  2FUD A;  4HWY A;  5CVN B;  3S3Q A;  1CJL A;  4MZS A;  3PBH A;  3CH3 X;  4PI3 A;  2F7D A;  3C9E A;  3K24 A;  5JA7 A;  2IPP B;  2VHF A;  1DF0 A;  4BS6 A;  3HD3 A;  3I06 A;  3N3G A;  2OUL A;  1YK8 A;  2Y6E A;  2R9C A;  2R9N A;  1KXR A;  3GCB A;  2FRQ A;  1U9W A;  3IEJ A;  4W5C A;  3RVV A;  1ME4 A;  3F5V A;  1CSB B;  1MS6 A;  3KFQ A;  4YYV A;  3P5X A;  5JH3 A;  2AS8 A;  5EGW A;  3HHA A;  4ZUX U;  1U9V A;  1NL6 A;  2CB5 A;  3B79 A;  1QMY A;  4I07 A;  1QOL A;  3U8E A;  1EWM A;  1Q6K A;  1F29 A;  4N79 A;  2ATO A;  2PRE A;  1PCI A;  1POP A;  1CVZ A;  3CH2 X;  3H6S A;  3HWN A;  4QRV A;  3CBJ A;  3PW3 A;  2CIO A;  4GUZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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